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Search of human proteins with 56117818
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56117818 muscle-restricted dual specificity phosphatase
isoform 1 [Homo sapiens]
(188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 385 e-108
gi|56117820 testis and skeletal muscle-specific dual specificity... 197 4e-51
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 196 8e-51
gi|51491914 dual specificity phosphatase and pro isomerase domai... 169 1e-42
gi|56237018 testis and skeletal muscle-specific dual specificity... 151 4e-37
gi|56117822 testis and skeletal muscle-specific dual specificity... 151 4e-37
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 144 4e-35
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 137 5e-33
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 88 5e-18
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 87 6e-18
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 85 4e-17
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 85 4e-17
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 84 9e-17
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 79 2e-15
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 78 5e-15
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 75 4e-14
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 74 6e-14
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 74 6e-14
gi|239582767 slingshot homolog 3 [Homo sapiens] 74 1e-13
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 74 1e-13
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 73 1e-13
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 71 6e-13
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 69 2e-12
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 68 5e-12
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 67 7e-12
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 67 1e-11
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 67 1e-11
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 67 1e-11
gi|37674210 slingshot 2 [Homo sapiens] 66 2e-11
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 66 2e-11
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 385 bits (990), Expect = e-108
Identities = 188/188 (100%), Positives = 188/188 (100%)
Query: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELW 60
MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELW
Sbjct: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELW 60
Query: 61 KLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNT 120
KLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNT
Sbjct: 61 KLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNT 120
Query: 121 PGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQ 180
PGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQ
Sbjct: 121 PGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQ 180
Query: 181 QLRGAGQS 188
QLRGAGQS
Sbjct: 181 QLRGAGQS 188
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 197 bits (501), Expect = 4e-51
Identities = 118/241 (48%), Positives = 139/241 (57%), Gaps = 59/241 (24%)
Query: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDA---------- 50
MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDA
Sbjct: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLR 60
Query: 51 ------------------------------ATANNRFELW------------------KL 62
AT N+ E+W +L
Sbjct: 61 RPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQL 120
Query: 63 GITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTP 121
GITHV+NAA G FY G S+ Y G+ A D P FD+S YF A +I AL+ P
Sbjct: 121 GITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVP 180
Query: 122 GAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQ 181
+VLVHC +GVSRSATLVLA+LM+ + ++L +A+ TV+ HR + PN GFL QL LD +
Sbjct: 181 QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNR 240
Query: 182 L 182
L
Sbjct: 241 L 241
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 196 bits (499), Expect = 8e-51
Identities = 99/168 (58%), Positives = 124/168 (73%), Gaps = 3/168 (1%)
Query: 17 PCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLY 76
P ++ ELE LL GK++C+ DEVWP L++GD ANNR EL +LGITHVLNA+H
Sbjct: 41 PFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRW- 99
Query: 77 CQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSR 135
+G P+ Y G + YLGV AHD P FD+S +F +AADFIHRAL+ PG K+LVHC VGVSR
Sbjct: 100 -RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSR 158
Query: 136 SATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQLR 183
SATLVLAYLML+ L+L +A+ V+ HR + PNRGFL QL LD++LR
Sbjct: 159 SATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLR 206
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 169 bits (429), Expect = 1e-42
Identities = 91/173 (52%), Positives = 114/173 (65%), Gaps = 1/173 (0%)
Query: 11 GEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNA 70
GE++ P ELE L G + V+EVWP L+IGD ATA +R+ L K G THVLNA
Sbjct: 28 GEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNA 87
Query: 71 AHKGLYCQGGPDFYGS-SVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHC 129
AH GPD+Y + Y GV A DLP FD+S +F AA FI RAL+ +K+LVHC
Sbjct: 88 AHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHC 147
Query: 130 VVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182
V+G SRSATLVLAYLM+H+ ++L A+ V ++R V PNRGFL QL LD+QL
Sbjct: 148 VMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 151 bits (381), Expect = 4e-37
Identities = 83/180 (46%), Positives = 119/180 (66%), Gaps = 4/180 (2%)
Query: 7 PELGGEDKATPC--PSILELEELLRAGKSSC-SRVDEVWPNLFIGDAATANNRFELWKLG 63
P++ G +A+P P++ L+ LL +++ + +DEVWP+LF+GDA A ++ +L +LG
Sbjct: 12 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71
Query: 64 ITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPG 122
ITHV+NAA G FY G S+ Y G+ A D P FD+S YF A +I AL+ P
Sbjct: 72 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 131
Query: 123 AKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182
+VLVHC +GVSRSATLVLA+LM+ + ++L +A+ TV+ HR + PN GFL QL LD +L
Sbjct: 132 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 151 bits (381), Expect = 4e-37
Identities = 83/180 (46%), Positives = 119/180 (66%), Gaps = 4/180 (2%)
Query: 7 PELGGEDKATPC--PSILELEELLRAGKSSC-SRVDEVWPNLFIGDAATANNRFELWKLG 63
P++ G +A+P P++ L+ LL +++ + +DEVWP+LF+GDA A ++ +L +LG
Sbjct: 105 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 164
Query: 64 ITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPG 122
ITHV+NAA G FY G S+ Y G+ A D P FD+S YF A +I AL+ P
Sbjct: 165 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 224
Query: 123 AKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182
+VLVHC +GVSRSATLVLA+LM+ + ++L +A+ TV+ HR + PN GFL QL LD +L
Sbjct: 225 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 284
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 144 bits (363), Expect = 4e-35
Identities = 79/171 (46%), Positives = 114/171 (66%), Gaps = 8/171 (4%)
Query: 16 TPCPSILELEELLRAGKSSC--SRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAH- 72
TPC +L+L+ L + + VDEVWPN+FI + + A N+ L +LGITH+LNAAH
Sbjct: 112 TPC--VLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHG 169
Query: 73 KGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVV 131
G+Y GP+FY G + YLGV D P+ DIS +F A++F+ AL T KVLV +
Sbjct: 170 TGVYT--GPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEM 227
Query: 132 GVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQL 182
G+SRSA LV+AYLM+ +++ +A++TVR+ R ++PN GFL QL L+++L
Sbjct: 228 GISRSAVLVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKL 278
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 137 bits (345), Expect = 5e-33
Identities = 77/175 (44%), Positives = 113/175 (64%), Gaps = 7/175 (4%)
Query: 20 SILELEELLRAGKSSCSR----VDEVWPNLFIGDAATANNRFELWKLGITHVLNAAH--K 73
S+ +L +LL G S +EV P +++G+A+ A + +L KLGITHVLNAA
Sbjct: 8 SVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRS 67
Query: 74 GLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVG 132
++ +FY S ++YLG+ A+D +F++SAYF AADFI +AL +VLVHC G
Sbjct: 68 FMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREG 127
Query: 133 VSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQLRGAGQ 187
SRS TLV+AYLM+ Q++ ++ A+ VRQ+R + PN GFL QLC+L+ +L G+
Sbjct: 128 YSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGK 182
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 87.8 bits (216), Expect = 5e-18
Identities = 66/190 (34%), Positives = 97/190 (51%), Gaps = 20/190 (10%)
Query: 5 SLPELGGEDKATPC----PSILELEELLRAGKSSCSRV-------DEVWPNLFIGDAATA 53
S PEL + ++TP P + + +G SSCS E+ P L++G A A
Sbjct: 131 SCPELCSK-QSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHA 189
Query: 54 NNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADF 113
+ + L LGIT ++N + C P+ + Y +P D DIS++F+ A DF
Sbjct: 190 SRKDMLDALGITALINVSAN---C---PNHFEGHYQYKSIPVEDNHKADISSWFNEAIDF 243
Query: 114 IHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFL 172
I N G +V VHC G+SRSAT+ LAYLM R+ L +A V+Q R + PN F+
Sbjct: 244 IDSIKNA-GGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFM 302
Query: 173 HQLCRLDQQL 182
QL + + Q+
Sbjct: 303 GQLLQFESQV 312
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 87.4 bits (215), Expect = 6e-18
Identities = 58/148 (39%), Positives = 78/148 (52%), Gaps = 8/148 (5%)
Query: 38 VDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHD 97
+ ++ +LF+G + A+NR L GIT ++NA + P+F Y+ VP D
Sbjct: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEI------PNFNWPQFEYVKVPLAD 80
Query: 98 LPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVI 157
+P I YF + AD IH GA LVHC GVSRSATL +AYLM + L +A
Sbjct: 81 MPHAPIGLYFDTVADKIHSVSRKHGA-TLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYN 139
Query: 158 TVRQHRWVF-PNRGFLHQLCRLDQQLRG 184
V+ R V PN GF QL ++QL G
Sbjct: 140 WVKARRPVIRPNVGFWRQLIDYERQLFG 167
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 84.7 bits (208), Expect = 4e-17
Identities = 63/176 (35%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 15 ATPCPSILELEELLRAGKSSCSRV-------DEVWPNLFIGDAATANNRFELWKLGITHV 67
A P P E L G SSC E+ P L++G A A R L LGIT +
Sbjct: 166 AIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITAL 225
Query: 68 LNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLV 127
LN + C P+ + Y +P D DIS++F A ++I + G +VLV
Sbjct: 226 LNVSSD---C---PNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRG-RVLV 278
Query: 128 HCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFLHQLCRLDQQL 182
HC G+SRSAT+ LAYLM+ +R+ L +A V+Q R + PN F+ QL + + Q+
Sbjct: 279 HCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 334
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 84.7 bits (208), Expect = 4e-17
Identities = 63/176 (35%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 15 ATPCPSILELEELLRAGKSSCSRV-------DEVWPNLFIGDAATANNRFELWKLGITHV 67
A P P E L G SSC E+ P L++G A A R L LGIT +
Sbjct: 75 AIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITAL 134
Query: 68 LNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLV 127
LN + C P+ + Y +P D DIS++F A ++I + G +VLV
Sbjct: 135 LNVSSD---C---PNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRG-RVLV 187
Query: 128 HCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFLHQLCRLDQQL 182
HC G+SRSAT+ LAYLM+ +R+ L +A V+Q R + PN F+ QL + + Q+
Sbjct: 188 HCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 243
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 83.6 bits (205), Expect = 9e-17
Identities = 55/144 (38%), Positives = 79/144 (54%), Gaps = 8/144 (5%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
E+ P LF+G + +++ L GIT VLN + C P+ + Y +P D
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSAS---C---PNHFEGLFRYKSIPVEDNQ 228
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
+ISA+F A FI N+ G +VLVHC G+SRSAT+ LAYLM +R+ L +A V
Sbjct: 229 MVEISAWFQEAIGFIDWVKNS-GGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFV 287
Query: 160 RQHRWVF-PNRGFLHQLCRLDQQL 182
+Q R V PN F+ QL + + Q+
Sbjct: 288 KQRRGVISPNFSFMGQLLQFETQV 311
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 79.0 bits (193), Expect = 2e-15
Identities = 50/144 (34%), Positives = 78/144 (54%), Gaps = 8/144 (5%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
E+ P L++G A A+ L L IT +LN + + + + + Y +P D
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRT------SEACATHLHYKWIPVEDSH 234
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
DIS++F A DFI + G KVLVHC G+SRS T+ +AYLM ++ L++A +
Sbjct: 235 TADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYI 293
Query: 160 RQHR-WVFPNRGFLHQLCRLDQQL 182
+Q R V PN GF+ QL + + ++
Sbjct: 294 KQRRSMVSPNFGFMGQLLQYESEI 317
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 77.8 bits (190), Expect = 5e-15
Identities = 52/147 (35%), Positives = 77/147 (52%), Gaps = 10/147 (6%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFY--GSSVSYLGVPAHD 97
++ PNL++G A + N L KLGI ++LN P+F+ Y +P D
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVT------PNLPNFFEKNGDFHYKQIPISD 259
Query: 98 LPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVI 157
++S +F A +FI AL+ VLVHC+ GVSRS T+ +AYLM LSL A
Sbjct: 260 HWSQNLSRFFPEAIEFIDEALSQ-NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYD 318
Query: 158 TVRQHRW-VFPNRGFLHQLCRLDQQLR 183
V++ + + PN F+ QL ++ LR
Sbjct: 319 LVKRKKSNISPNFNFMGQLLDFERSLR 345
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 74.7 bits (182), Expect = 4e-14
Identities = 50/139 (35%), Positives = 73/139 (52%), Gaps = 9/139 (6%)
Query: 38 VDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHD 97
++++ P L+IG+ A + +L K +TH+L+ ++ P G V YL +PA D
Sbjct: 5 MNKILPGLYIGNFKDARDAEQLSKNKVTHILS-----VHDSARPMLEG--VKYLCIPAAD 57
Query: 98 LPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVI 157
P +++ +F + FIH G LVHC+ GVSRS TLV+AY+M A+
Sbjct: 58 SPSQNLTRHFKESIKFIHEC-RLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALH 116
Query: 158 TVRQHR-WVFPNRGFLHQL 175
TVR R PN GF QL
Sbjct: 117 TVRAGRSCANPNVGFQRQL 135
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 74.3 bits (181), Expect = 6e-14
Identities = 50/144 (34%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 33 SSCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLG 92
SS +V + P L +G A++ L K +TH+LN A+ G + + S +Y
Sbjct: 61 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAY------GVENAFLSDFTYKS 114
Query: 93 VPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSL 152
+ DLP+ +I +YF +FI A G VLVHC GVSR+A +V+ +LM ++ S
Sbjct: 115 ISILDLPETNILSYFPECFEFIEEAKRKDGV-VLVHCNAGVSRAAAIVIGFLMNSEQTSF 173
Query: 153 RQAVITVRQHR-WVFPNRGFLHQL 175
A V+ R + PN GF+ QL
Sbjct: 174 TSAFSLVKNARPSICPNSGFMEQL 197
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 74.3 bits (181), Expect = 6e-14
Identities = 51/152 (33%), Positives = 75/152 (49%), Gaps = 8/152 (5%)
Query: 34 SCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGV 93
S S + ++ +L+I + ANN+ L IT V+N + + + + + Y+ V
Sbjct: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVV------NTLYEDIQYMQV 69
Query: 94 PAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLR 153
P D P+ + +F AD IH G + L+HC GVSRSA L LAYLM + +SL
Sbjct: 70 PVADSPNSRLCDFFDPIADHIHSVEMKQG-RTLLHCAAGVSRSAALCLAYLMKYHAMSLL 128
Query: 154 QAVITVRQHRWVF-PNRGFLHQLCRLDQQLRG 184
A + R + PN GF QL + QL G
Sbjct: 129 DAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFG 160
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 73.6 bits (179), Expect = 1e-13
Identities = 51/140 (36%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 37 RVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAH 96
R ++P+L++G A N EL + +TH+LN A + +FY +Y V
Sbjct: 328 RASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREI------DNFYPERFTYHNVRLW 381
Query: 97 DLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAV 156
D + ++ FI A G VLVHC +GVSRSA VLAY M SL QA+
Sbjct: 382 DEESAQLLPHWKETHRFIEAA-RAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQAL 440
Query: 157 ITVRQHRWVF-PNRGFLHQL 175
V++ R + PN GFL QL
Sbjct: 441 RHVQELRPIARPNPGFLRQL 460
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 73.6 bits (179), Expect = 1e-13
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 8/144 (5%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAA-HKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
+ P LF+G+ A + + +L I +V+N H LY + +Y +PA D
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLY-----HYEKGLFNYKRLPATDSN 379
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
++ YF A +FI A + G +L+HC GVSRSAT+V+AYLM H R+++ A V
Sbjct: 380 KQNLRQYFEEAFEFIEEA-HQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFV 438
Query: 160 RQHRWVF-PNRGFLHQLCRLDQQL 182
+ R + PN F+ QL ++ L
Sbjct: 439 KGKRPIISPNLNFMGQLLEFEEDL 462
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 73.2 bits (178), Expect = 1e-13
Identities = 51/144 (35%), Positives = 81/144 (56%), Gaps = 7/144 (4%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100
+ PNL++G N+ + + GI +VLNA++ C PDF S +L VP +D
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNT---CPK-PDFIPES-HFLRVPVNDSFC 216
Query: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160
I + + DFI +A + G VLVHC+ G+SRSAT+ +AY+M +SL +A V+
Sbjct: 217 EKILPWLDKSVDFIEKAKASNGC-VLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
Query: 161 QHR-WVFPNRGFLHQLCRLDQQLR 183
+ R + PN FL QL +++++
Sbjct: 276 EKRPTISPNFNFLGQLLDYEKKIK 299
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 70.9 bits (172), Expect = 6e-13
Identities = 45/144 (31%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
++ +LF+ + AN++ L IT ++NA+ + + + + + Y+ VP D
Sbjct: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVV------NVFFEGIQYIKVPVTDAR 77
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
D + +F AD IH ++ + L+HC+ GVSRSA+L LAYLM + +SL A
Sbjct: 78 DSRLYDFFDPIADLIH-TIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWT 136
Query: 160 RQHRWVF-PNRGFLHQLCRLDQQL 182
+ R + PN GF QL + +L
Sbjct: 137 KSRRPIIRPNNGFWEQLINYEFKL 160
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 68.9 bits (167), Expect = 2e-12
Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
+V P L++G+ A + +L + ITH+++ P ++YL +P D P
Sbjct: 7 KVLPGLYLGNFIDAKDLDQLGRNKITHIISIHES-------PQPLLQDITYLRIPVADTP 59
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
+ I +F +FIH G LVHC G+SRS T+V AY+M L R + +
Sbjct: 60 EVPIKKHFKECINFIH-CCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAI 118
Query: 160 RQHRWVF-PNRGFLHQL 175
+ R + PN GF QL
Sbjct: 119 KATRPIANPNPGFRQQL 135
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 67.8 bits (164), Expect = 5e-12
Identities = 53/144 (36%), Positives = 75/144 (52%), Gaps = 8/144 (5%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100
V P+LF+G A A +L + G+T +N + + Q GP G V+ L VP D P
Sbjct: 22 VAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQ----QPGPRAPG--VAELRVPVFDDPA 75
Query: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160
D+ A+ + A+ GA LV+C G SRSA + AYLM H+ LSL +A V+
Sbjct: 76 EDLLAHLEPTCAAMEAAVRAGGA-CLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVK 134
Query: 161 QHRWVF-PNRGFLHQLCRLDQQLR 183
R V PN GF QL + ++ L+
Sbjct: 135 SARPVAEPNPGFWSQLQKYEEALQ 158
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 67.4 bits (163), Expect = 7e-12
Identities = 53/182 (29%), Positives = 82/182 (45%), Gaps = 18/182 (9%)
Query: 2 AETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELWK 61
++ LP E +P PS S + ++ P L++G A + N L K
Sbjct: 221 SDRELPSSATESDGSPVPS------------SQPAFPVQILPYLYLGCAKDSTNLDVLGK 268
Query: 62 LGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTP 121
GI ++LN +G +Y +P D ++S +F A FI A +
Sbjct: 269 YGIKYILNVTPN----LPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEA-RSK 323
Query: 122 GAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRW-VFPNRGFLHQLCRLDQ 180
VLVHC+ G+SRS T+ +AYLM LSL A V++ + + PN F+ QL ++
Sbjct: 324 KCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFER 383
Query: 181 QL 182
L
Sbjct: 384 TL 385
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 66.6 bits (161), Expect = 1e-11
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100
++ +L++G A+N EL G+ ++LN + +F+ +Y + +D
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREI------DNFFPGLFAYHNIRVYDEET 365
Query: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160
D+ A+++ A FI++A +K LVHC +GVSRSA+ V+AY M L +A V+
Sbjct: 366 TDLLAHWNEAYHFINKAKRNH-SKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424
Query: 161 QHRWVF-PNRGFLHQLCRLDQQLRGAGQ 187
Q R + PN GF+ QL + L + Q
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGILDASKQ 452
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 66.6 bits (161), Expect = 1e-11
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100
++ +L++G A+N EL G+ ++LN + +F+ +Y + +D
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREI------DNFFPGLFAYHNIRVYDEET 376
Query: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160
D+ A+++ A FI++A +K LVHC +GVSRSA+ V+AY M L +A V+
Sbjct: 377 TDLLAHWNEAYHFINKAKRNH-SKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435
Query: 161 QHRWVF-PNRGFLHQLCRLDQQLRGAGQ 187
Q R + PN GF+ QL + L + Q
Sbjct: 436 QKRSITRPNAGFMRQLSEYEGILDASKQ 463
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 66.6 bits (161), Expect = 1e-11
Identities = 46/148 (31%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Query: 41 VWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPD 100
++ +L++G A+N EL G+ ++LN + +F+ +Y + +D
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREI------DNFFPGLFAYHNIRVYDEET 365
Query: 101 FDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVR 160
D+ A+++ A FI++A +K LVHC +GVSRSA+ V+AY M L +A V+
Sbjct: 366 TDLLAHWNEAYHFINKAKRNH-SKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424
Query: 161 QHRWVF-PNRGFLHQLCRLDQQLRGAGQ 187
Q R + PN GF+ QL + L + Q
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGILDASKQ 452
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 8/137 (5%)
Query: 40 EVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLP 99
+++ ++F+G A+N +L G+ ++LN + +F+ Y + +D
Sbjct: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREI------DNFFPGVFEYHNIRVYDEE 363
Query: 100 DFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITV 159
D+ AY++ FI +A G+K LVHC +GVSRSA+ V+AY M +L +A V
Sbjct: 364 ATDLLAYWNDTYKFISKA-KKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
Query: 160 RQHRWVF-PNRGFLHQL 175
++ R V PN F+ QL
Sbjct: 423 KERRTVTKPNPSFMRQL 439
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 65.9 bits (159), Expect = 2e-11
Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 8/124 (6%)
Query: 61 KLGITHVLNAA-HKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALN 119
+L I +V+N H LY + +Y +PA D ++ YF A +FI A +
Sbjct: 3 RLNIGYVINVTTHLPLY-----HYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEA-H 56
Query: 120 TPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFLHQLCRL 178
G +L+HC GVSRSAT+V+AYLM H R+++ A V+ R + PN F+ QL
Sbjct: 57 QCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEF 116
Query: 179 DQQL 182
++ L
Sbjct: 117 EEDL 120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,604,620
Number of Sequences: 37866
Number of extensions: 312019
Number of successful extensions: 644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 537
Number of HSP's gapped (non-prelim): 91
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.