Guide to the Human Genome
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Search of human proteins with 134288871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|134288871 aminoglycoside phosphotransferase domain
containing 1 isoform 1 [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|134288871 aminoglycoside phosphotransferase domain containing...   746   0.0  
gi|134288902 aminoglycoside phosphotransferase domain containing...   438   e-123
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan...    36   0.064
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     36   0.064
gi|30039692 NIMA-related kinase 8 [Homo sapiens]                       32   1.2  
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]      32   1.2  
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]      32   1.2  
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]      32   1.2  
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]      32   1.2  
gi|14249180 wingless-type MMTV integration site family, member 5...    30   4.6  
gi|17402919 wingless-type MMTV integration site family, member 5...    30   4.6  
gi|4758012 clathrin heavy chain 1 [Homo sapiens]                       30   4.6  
gi|50539414 cellular modulator of immune recognition isoform 7 [...    30   4.6  
gi|50539412 cellular modulator of immune recognition isoform 6 [...    30   4.6  
gi|50539410 cellular modulator of immune recognition isoform 8 [...    30   4.6  
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       29   7.8  

>gi|134288871 aminoglycoside phosphotransferase domain containing 1
           isoform 1 [Homo sapiens]
          Length = 373

 Score =  746 bits (1927), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT 60
           MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT
Sbjct: 1   MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT 60

Query: 61  EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS 120
           EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS
Sbjct: 61  EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS 120

Query: 121 YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN 180
           YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN
Sbjct: 121 YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN 180

Query: 181 VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSA 240
           VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSA
Sbjct: 181 VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSA 240

Query: 241 SGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAV 300
           SGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAV
Sbjct: 241 SGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAV 300

Query: 301 EKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIW 360
           EKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIW
Sbjct: 301 EKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIW 360

Query: 361 FETAKSYESGISM 373
           FETAKSYESGISM
Sbjct: 361 FETAKSYESGISM 373


>gi|134288902 aminoglycoside phosphotransferase domain containing 1
           isoform 2 [Homo sapiens]
          Length = 220

 Score =  438 bits (1127), Expect = e-123
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT 60
           MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT
Sbjct: 1   MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPT 60

Query: 61  EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS 120
           EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS
Sbjct: 61  EYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKS 120

Query: 121 YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN 180
           YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN
Sbjct: 121 YLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKN 180

Query: 181 VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRE 220
           VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRE
Sbjct: 181 VPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRE 220


>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
           factor 2, partial [Homo sapiens]
          Length = 803

 Score = 35.8 bits (81), Expect = 0.064
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 50  VYVSKTKDGPTEYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASL 109
           V + +TK  PT   L +S T +S NPDL++  + I+ F      P   +   K D  +  
Sbjct: 564 VGLRQTKHIPT--ALPVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRY 621

Query: 110 VSVDSGSEIKSYLVRLL-----TYLPGR-PIAELPVSPQLLYEIGKLAAKLDKTLQR 160
           + +   +  K  +++ +     T  P +  + E+ V+P+ + +  +L  +L K   R
Sbjct: 622 IMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADR 678


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 35.8 bits (81), Expect = 0.064
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 50  VYVSKTKDGPTEYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASL 109
           V + +TK  PT   L +S T +S NPDL++  + I+ F      P   +   K D  +  
Sbjct: 564 VGLRQTKHIPT--ALPVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRY 621

Query: 110 VSVDSGSEIKSYLVRLL-----TYLPGR-PIAELPVSPQLLYEIGKLAAKLDKTLQR 160
           + +   +  K  +++ +     T  P +  + E+ V+P+ + +  +L  +L K   R
Sbjct: 622 IMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADR 678


>gi|30039692 NIMA-related kinase 8 [Homo sapiens]
          Length = 692

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 134 IAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKNVPLLEKYLYALG- 192
           I ++PV  Q+  E  + A    + L+  +HP +   + ENF   L++  L+    YA G 
Sbjct: 32  IKQIPVE-QMTKEERQAAQNECQVLKLLNHPNVIEYY-ENF---LEDKALMIAMEYAPGG 86

Query: 193 ------QNRNREIVEH--VIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSASGNA 244
                 Q R   ++E   ++H F + ++         I H DL   NIL++  +      
Sbjct: 87  TLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIG 146

Query: 245 EYQVSGILDFGDMSY 259
           ++ +S IL     +Y
Sbjct: 147 DFGISKILSSKSKAY 161


>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
          Length = 3095

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 41  PSYDDQNFH-VYVSKTKDGPTEYVLKISNTKASKN-PDLIEVQNHIIMFLK 89
           P Y D+N   VY+  T D   E +L +   KA KN PDL    N+++  +K
Sbjct: 938 PEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIK 988


>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
          Length = 3069

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 41  PSYDDQNFH-VYVSKTKDGPTEYVLKISNTKASKN-PDLIEVQNHIIMFLK 89
           P Y D+N   VY+  T D   E +L +   KA KN PDL    N+++  +K
Sbjct: 938 PEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIK 988


>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
          Length = 3174

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 41  PSYDDQNFH-VYVSKTKDGPTEYVLKISNTKASKN-PDLIEVQNHIIMFLK 89
           P Y D+N   VY+  T D   E +L +   KA KN PDL    N+++  +K
Sbjct: 938 PEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIK 988


>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
          Length = 3135

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 41  PSYDDQNFH-VYVSKTKDGPTEYVLKISNTKASKN-PDLIEVQNHIIMFLK 89
           P Y D+N   VY+  T D   E +L +   KA KN PDL    N+++  +K
Sbjct: 938 PEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIK 988


>gi|14249180 wingless-type MMTV integration site family, member 5B
           precursor [Homo sapiens]
          Length = 359

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 4/57 (7%)

Query: 297 LTAVEKGALFLLVCSRFCQSLVMAAYS----CQLYPENKDYLMVTAKTGWKHLQQMF 349
           L  V++  +F++     C  L   +      CQLY E+  Y+   AKTG K  Q  F
Sbjct: 31  LNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQF 87


>gi|17402919 wingless-type MMTV integration site family, member 5B
           precursor [Homo sapiens]
          Length = 359

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 4/57 (7%)

Query: 297 LTAVEKGALFLLVCSRFCQSLVMAAYS----CQLYPENKDYLMVTAKTGWKHLQQMF 349
           L  V++  +F++     C  L   +      CQLY E+  Y+   AKTG K  Q  F
Sbjct: 31  LNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQF 87


>gi|4758012 clathrin heavy chain 1 [Homo sapiens]
          Length = 1675

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 13/47 (27%), Positives = 26/47 (55%)

Query: 164  PKLSSLHRENFIWNLKNVPLLEKYLYALGQNRNREIVEHVIHLFKEE 210
            P+L      N+   +K +PL++ YL ++  + N+ + E + +LF  E
Sbjct: 1428 PRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITE 1474


>gi|50539414 cellular modulator of immune recognition isoform 7
           [Homo sapiens]
          Length = 291

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 13/93 (13%)

Query: 32  LKVSKVRPLPSYDDQNFHVYVSKTKDGPTE---------YVLKISNTKASKNPDLIEVQN 82
           + + ++  +PS D  +  VY SKTK+   E         ++   SN   + +P       
Sbjct: 3   MPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPA 62

Query: 83  HIIMFLKAAGFPTAS----VCHTKGDNTASLVS 111
            +  F + +  P++     +CH +GD+ + L++
Sbjct: 63  PVSSFSRTSITPSSQDICRICHCEGDDESPLIT 95


>gi|50539412 cellular modulator of immune recognition isoform 6
           [Homo sapiens]
          Length = 291

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 13/93 (13%)

Query: 32  LKVSKVRPLPSYDDQNFHVYVSKTKDGPTE---------YVLKISNTKASKNPDLIEVQN 82
           + + ++  +PS D  +  VY SKTK+   E         ++   SN   + +P       
Sbjct: 3   MPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPA 62

Query: 83  HIIMFLKAAGFPTAS----VCHTKGDNTASLVS 111
            +  F + +  P++     +CH +GD+ + L++
Sbjct: 63  PVSSFSRTSITPSSQDICRICHCEGDDESPLIT 95


>gi|50539410 cellular modulator of immune recognition isoform 8
           [Homo sapiens]
          Length = 291

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 13/93 (13%)

Query: 32  LKVSKVRPLPSYDDQNFHVYVSKTKDGPTE---------YVLKISNTKASKNPDLIEVQN 82
           + + ++  +PS D  +  VY SKTK+   E         ++   SN   + +P       
Sbjct: 3   MPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPA 62

Query: 83  HIIMFLKAAGFPTAS----VCHTKGDNTASLVS 111
            +  F + +  P++     +CH +GD+ + L++
Sbjct: 63  PVSSFSRTSITPSSQDICRICHCEGDDESPLIT 95


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 21/107 (19%)

Query: 156 KTLQRFHHPKLSSLHRENFIWNLKNVPLLEKYLYALGQNRNREIVEHV--IHLFKEEVMT 213
           +  + F+H +   L  E    NL+ V  L+KY         +++  H+  +  + +++  
Sbjct: 752 RLFRHFYHKQHLCLVFEPLSMNLREV--LKKY--------GKDVGLHIKAVRSYSQQLFL 801

Query: 214 KLSHFREC-INHGDLNDHNILIESSKSASGNAEYQVSGILDFGDMSY 259
            L   + C I H D+   NIL+  SK+        +  + DFG  S+
Sbjct: 802 ALKLLKRCNILHADIKPDNILVNESKT--------ILKLCDFGSASH 840


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,983,205
Number of Sequences: 37866
Number of extensions: 541663
Number of successful extensions: 1365
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1360
Number of HSP's gapped (non-prelim): 16
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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