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Search of human proteins with 55956890
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956890 kelch/ankyrin repeat containing cyclin A1
interacting protein isoform b [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956890 kelch/ankyrin repeat containing cyclin A1 interactin... 623 e-179
gi|55956888 kelch/ankyrin repeat containing cyclin A1 interactin... 489 e-139
gi|55925604 kelch-like 18 [Homo sapiens] 43 4e-04
gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens] 40 0.003
gi|24475847 influenza virus NS1A binding protein [Homo sapiens] 39 0.005
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 37 0.020
gi|61743978 stabilin 1 precursor [Homo sapiens] 37 0.026
gi|17017980 kelch-like 4 isoform 2 [Homo sapiens] 36 0.034
gi|17017982 kelch-like 4 isoform 1 [Homo sapiens] 36 0.034
gi|38194229 kelch-like 17 [Homo sapiens] 36 0.034
gi|148664209 kelch-like 10 [Homo sapiens] 36 0.045
gi|88196794 kelch-like 35 [Homo sapiens] 36 0.045
gi|34101268 kelch-like 8 [Homo sapiens] 35 0.076
gi|41393547 neuroblastoma-amplified protein [Homo sapiens] 35 0.100
gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 33 0.22
gi|18152779 scavenger receptor cysteine rich domain containing, ... 33 0.29
gi|31881798 muskelin 1, intracellular mediator containing kelch ... 33 0.38
gi|223890246 muskelin 1, intracellular mediator containing kelch... 33 0.38
gi|40018614 DRE1 protein [Homo sapiens] 32 0.65
gi|23397572 kelch-like 34 [Homo sapiens] 31 1.1
gi|5174473 intracisternal A particle-promoted polypeptide isofor... 31 1.4
gi|223890235 intracisternal A particle-promoted polypeptide isof... 31 1.4
gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens] 30 1.9
gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens] 30 1.9
gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens] 30 1.9
gi|40807500 kelch-like 20 [Homo sapiens] 30 2.5
gi|134244285 Notch homolog 3 [Homo sapiens] 30 3.2
gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo... 29 4.2
gi|11056006 kelch-like 12 [Homo sapiens] 29 4.2
gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens] 29 5.5
>gi|55956890 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform b [Homo sapiens]
Length = 288
Score = 623 bits (1606), Expect = e-179
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV
Sbjct: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
Query: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW
Sbjct: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
Query: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE
Sbjct: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
Query: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKSFLSPQGGTTC 240
GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKSFLSPQGGTTC
Sbjct: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKSFLSPQGGTTC 240
Query: 241 CSSFDGTACKACEQWAGVPEGAPWTTASLMFCGRALCCAVWWRNSDQS 288
CSSFDGTACKACEQWAGVPEGAPWTTASLMFCGRALCCAVWWRNSDQS
Sbjct: 241 CSSFDGTACKACEQWAGVPEGAPWTTASLMFCGRALCCAVWWRNSDQS 288
>gi|55956888 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform a [Homo sapiens]
Length = 349
Score = 489 bits (1260), Expect = e-139
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV
Sbjct: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
Query: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW
Sbjct: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
Query: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE
Sbjct: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
Query: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK 229
GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK
Sbjct: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK 229
>gi|55925604 kelch-like 18 [Homo sapiens]
Length = 574
Score = 42.7 bits (99), Expect = 4e-04
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 33 CTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWL 92
CT + G Y VGGL + G + + VFDP R + RS A V+G L
Sbjct: 283 CTSIAGLIYAVGGLNSAG--DSLNVVEVFDPIANCWERCRPM-TTARSRVGVAVVNGL-L 338
Query: 93 CVVGGWDGSRRLATVTALDTERGVW 117
+GG+DG RL+TV A + E W
Sbjct: 339 YAIGGYDGQLRLSTVEAYNPETDTW 363
Score = 32.7 bits (73), Expect = 0.38
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 11/133 (8%)
Query: 22 RDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSH 81
R AR+ + G Y +GG + S ++P R+G+ S RS
Sbjct: 320 RPMTTARSRVGVAVVNGLLYAIGGY---DGQLRLSTVEAYNPETDTWTRVGSMNSK-RSA 375
Query: 82 HDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCTRIS 141
+DG+ + V GG+DG+ L++V E W T + AG++ +
Sbjct: 376 MGTVVLDGQ-IYVCGGYDGNSSLSSVETYSPETDKWTVVTSMSSNRSAAGVT------VF 428
Query: 142 DRELQVAGREGGI 154
+ + V+G G+
Sbjct: 429 EGRIYVSGGHDGL 441
>gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]
Length = 686
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 15 WAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGAR 74
W PV + AR HS +G + GGL G + EP + + P +
Sbjct: 521 WVRIPVEGEVPEARHSHSACTWQGGALIAGGL--GASEEPLNSVLFLRPISCGFLWESVD 578
Query: 75 GSPP---RSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCP-PA 130
PP R H A ++G+ L V G W S VT ++ G+ + P P
Sbjct: 579 IQPPITPRYSHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPL 638
Query: 131 GLSSHTCTRI-SDRELQVAGREGGIHTQRRYGSIYTLRLDPSA 172
L +HT + +++L + G G + Y + +T+ LD S+
Sbjct: 639 MLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSS 681
>gi|24475847 influenza virus NS1A binding protein [Homo sapiens]
Length = 642
Score = 38.9 bits (89), Expect = 0.005
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 26 LARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAA 85
+AR L G+ ++ GG A S ++DP R + +G SP RS+ A
Sbjct: 547 VARRGAGVAVLNGKLFVCGGFDGSHA---ISCVEMYDPTRNEWKMMGNMTSP-RSNAGIA 602
Query: 86 PVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT 121
V G + VGG+DG+ L TV + E W +T
Sbjct: 603 TV-GNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYT 637
Score = 30.0 bits (66), Expect = 2.5
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPP--RSHHDAAPVDGRWLC 93
L G+ Y+VGG G ++ + VFDP +L +P R H A G +L
Sbjct: 461 LNGKLYIVGGSDPYG-QKGLKNCDVFDPV----TKLWTSCAPLNIRRHQSAVCELGGYLY 515
Query: 94 VVGGWDGSRRLATVTALDTERGVW 117
++GG + L TV + E W
Sbjct: 516 IIGGAESWNCLNTVERYNPENNTW 539
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 37.0 bits (84), Expect = 0.020
Identities = 55/198 (27%), Positives = 72/198 (36%), Gaps = 23/198 (11%)
Query: 27 ARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDP-ARGQAVRLG-----ARGSPPRS 80
AR H G L+GG LA G+ ++D F P RG L + G P +
Sbjct: 278 ARHSHVAVAWAGSLVLMGGELADGSL--TNDVWAFSPLGRGHWELLAPPASSSSGPPGLA 335
Query: 81 HHDAAPVDGRWLCVVGGWDG----SRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHT 136
H AA VD WL V GG S L T G WE G PPA
Sbjct: 336 GHAAALVDDVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQ-VIPAGGRPPAATGHSM 394
Query: 137 CTRISDRELQVAG--REGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCH-TASRSGHCAA 193
R L V G R R S +D T ++G R+ H A+
Sbjct: 395 VFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGRDGLQGPRERAFHTAS 454
Query: 194 LLQTPGPHPGHQLLLFGG 211
+L G+ ++++GG
Sbjct: 455 VL-------GNYMVVYGG 465
Score = 31.2 bits (69), Expect = 1.1
Identities = 44/190 (23%), Positives = 65/190 (34%), Gaps = 21/190 (11%)
Query: 28 RAFHSCTEL---RGRFYLVGGLLAGGAREP----SSDTVVFDPARG-QAVRLGARGSPPR 79
R+FH+ + RG YL+GGL AGG + T+ + + Q V L P
Sbjct: 1499 RSFHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVEL-----PAV 1553
Query: 80 SHHDAAPVDGRWLCVVGGWDGSRRL-ATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCT 138
+ H G L +VGG+ + G W +G PP GL H+
Sbjct: 1554 AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTWV--SGAQSGTPPTGLYGHSAV 1611
Query: 139 --RISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGC---HTASRSGHCAA 193
+D G + +Y+L + +G + G
Sbjct: 1612 YHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRG 1671
Query: 194 LLQTPGPHPG 203
L Q PG PG
Sbjct: 1672 LGQVPGEQPG 1681
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 36.6 bits (83), Expect = 0.026
Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 11/109 (10%)
Query: 150 REGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCHTASRSGH-CAALLQTPGPHPGHQLLL 208
RE ++ RR+ +L + R C + G + + CA +Q P PG
Sbjct: 1269 REKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPG----F 1324
Query: 209 FGGCNLAEPEVAGHWS----HGKIKSFLSPQGGTTCCSSFDGTACKACE 253
FG L EP G HG+ + G C F GTAC+ CE
Sbjct: 1325 FG--TLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCE 1371
>gi|17017980 kelch-like 4 isoform 2 [Homo sapiens]
Length = 720
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 38 GRFYLVGGLLAGGAREPS--SDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
G Y+VGG A + S SD V +G + A S PR P+ G L VV
Sbjct: 617 GFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPL-GDKLYVV 675
Query: 96 GGWDGSRRLATVTALDTERGVWE 118
GG+DG L TV + D +R W+
Sbjct: 676 GGYDGHTYLNTVESYDAQRNEWK 698
>gi|17017982 kelch-like 4 isoform 1 [Homo sapiens]
Length = 718
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 38 GRFYLVGGLLAGGAREPS--SDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
G Y+VGG A + S SD V +G + A S PR P+ G L VV
Sbjct: 617 GFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPL-GDKLYVV 675
Query: 96 GGWDGSRRLATVTALDTERGVWE 118
GG+DG L TV + D +R W+
Sbjct: 676 GGYDGHTYLNTVESYDAQRNEWK 698
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W PVA L R+ L G Y+ GG + T + + + GA S
Sbjct: 510 WSPVA-SMLSRRSSAGVAVLEGALYVAGG---------NDGTSCLNSVERYSPKAGAWES 559
Query: 77 PP-----RSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEA 119
RS HD +DG WL VGG DGS L ++ + W A
Sbjct: 560 VAPMNIRRSTHDLVAMDG-WLYAVGGNDGSSSLNSIEKYNPRTNKWVA 606
Score = 32.7 bits (73), Expect = 0.38
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
L G Y GG + +DP G + A S R + A +DG L V
Sbjct: 434 LHGLLYSAGGYDGASCLNSAER---YDPLTGTWTSVAAM-STRRRYVRVATLDGN-LYAV 488
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+D S LATV + + VW
Sbjct: 489 GGYDSSSHLATVEKYEPQVNVW 510
Score = 32.3 bits (72), Expect = 0.50
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 16/94 (17%)
Query: 89 GRWLCVVGGWDGSRRLATVTALDTERGVW--EAWTGTPGDC-----------PPAGLSSH 135
G L VGG+DG+ LATV + D W E GT C G
Sbjct: 388 GNRLYAVGGYDGTSDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYSAGGYDGA 447
Query: 136 TCTRISDRELQVAG---REGGIHTQRRYGSIYTL 166
+C ++R + G + T+RRY + TL
Sbjct: 448 SCLNSAERYDPLTGTWTSVAAMSTRRRYVRVATL 481
>gi|148664209 kelch-like 10 [Homo sapiens]
Length = 608
Score = 35.8 bits (81), Expect = 0.045
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V + RA+H L+G Y++GG + + + FDP + ++ S
Sbjct: 318 WVNVTCEEESPRAYHGAAYLKGYVYIIGGF---DSVDYFNSVKRFDPVKKTWHQVAPMHS 374
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVW 117
R + + V G ++ +GG+DG RL T + E W
Sbjct: 375 --RRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQW 413
Score = 28.1 bits (61), Expect = 9.3
Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 28 RAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPV 87
R+ S T L G+ Y+ GG E V++ Q + +P RS V
Sbjct: 423 RSDASATTLYGKVYICGGF---NGNECLFTAEVYNTESNQWTVI----APMRSRRSGIGV 475
Query: 88 D--GRWLCVVGGWDGSRRLATVTALDTERGVW 117
G + VGG+DG+ RL + A W
Sbjct: 476 IAYGEHVYAVGGFDGANRLRSAEAYSPVANTW 507
>gi|88196794 kelch-like 35 [Homo sapiens]
Length = 363
Score = 35.8 bits (81), Expect = 0.045
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 14/143 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W P+ R+ + LR Y+ GG + S D +F +++ +
Sbjct: 109 WTPLPSLPGYTRSEFAACALRNDVYVSGGHIN------SHDVWMFSSHLHTWIKVASLHK 162
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHT 136
R H A V G+ L VGG+DG RRL +V D W A P +SS
Sbjct: 163 G-RWRHKMAVVQGQ-LFAVGGFDGLRRLHSVERYDPFSNTWAAAAPL-----PEAVSSAA 215
Query: 137 CTRISDRELQVAG-REGGIHTQR 158
+ + + G R+GG++T +
Sbjct: 216 VASCAGKLFVIGGARQGGVNTDK 238
>gi|34101268 kelch-like 8 [Homo sapiens]
Length = 620
Score = 35.0 bits (79), Expect = 0.076
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 7/119 (5%)
Query: 28 RAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPV 87
RA + ++L G Y+VGG P S +DP + + A + PR A V
Sbjct: 497 RAGNGVSKLHGCLYVVGGF---DDNSPLSSVERYDPRSNKWDYVAAL-TTPRGGVGIATV 552
Query: 88 DGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDC-PPAGLSSHTCTRISDREL 145
G+ + VGG +G+ L TV A D WE G+ C AG++ +C R++
Sbjct: 553 MGK-IFAVGGHNGNAYLNTVEAFDPVLNRWEL-VGSVSHCRAGAGVAVCSCLTSQIRDV 609
>gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
Length = 2371
Score = 34.7 bits (78), Expect = 0.100
Identities = 17/34 (50%), Positives = 19/34 (55%)
Query: 183 HTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAE 216
H S S H + T HPGH+LLL GGC AE
Sbjct: 227 HCFSFSSHYPHGINTAIYHPGHRLLLVGGCETAE 260
>gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens]
Length = 589
Score = 33.5 bits (75), Expect = 0.22
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 46 LLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLA 105
++ G ++ FD Q R+G + S H A G L VVGG+ G++R
Sbjct: 496 IMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALA--SGNKLYVVGGYFGTQRCK 553
Query: 106 TVTALDTERGVWEAWTGTPGDCPPAGLSS 134
T+ D W T P P S
Sbjct: 554 TLDCYDPTSDTWNCITTVPYSLIPTAFVS 582
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 33.1 bits (74), Expect = 0.29
Identities = 65/278 (23%), Positives = 83/278 (29%), Gaps = 79/278 (28%)
Query: 7 PGRAAGSGWAWR-----------PVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPS 55
P A WAW+ P ALL A + + GR LVGG
Sbjct: 300 PSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGP--------- 350
Query: 56 SDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERG 115
P RG+ L A G D D R C G + + RG
Sbjct: 351 ------GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRG 404
Query: 116 -VWEAWTGTPG------DCPPAGLSSHTCTRISDRELQVAGREG-GIHTQRRYGSIYTLR 167
V G G DC G H C D AG E G+ Q
Sbjct: 405 PVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQ---------- 454
Query: 168 LDPSARTYCYKQEGCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGK 227
Q+G T + TP P GH L+ G H G+
Sbjct: 455 -----------QDGSETTR--------VPTPRPRDGHLRLVNGA----------HRCEGR 485
Query: 228 IKSFLSPQGGTTCCSSFD----GTACK--ACEQWAGVP 259
++ +L + GT C ++D G C+ C Q P
Sbjct: 486 VELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAP 523
>gi|31881798 muskelin 1, intracellular mediator containing kelch
motifs isoform 2 [Homo sapiens]
Length = 735
Score = 32.7 bits (73), Expect = 0.38
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 66 GQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT-GTP 124
G+ R G RG H V + + GGWDG++ LA A + W + T
Sbjct: 263 GEDNRPGMRGG----HQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTE 318
Query: 125 GDCPPAGLSSH-TCTRISDRELQVAGR 150
+ P+ S H C I R++ GR
Sbjct: 319 KENGPSARSCHKMCIDIQRRQIYTLGR 345
>gi|223890246 muskelin 1, intracellular mediator containing kelch
motifs isoform 1 [Homo sapiens]
Length = 712
Score = 32.7 bits (73), Expect = 0.38
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 66 GQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT-GTP 124
G+ R G RG H V + + GGWDG++ LA A + W + T
Sbjct: 240 GEDNRPGMRGG----HQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTE 295
Query: 125 GDCPPAGLSSH-TCTRISDRELQVAGR 150
+ P+ S H C I R++ GR
Sbjct: 296 KENGPSARSCHKMCIDIQRRQIYTLGR 322
>gi|40018614 DRE1 protein [Homo sapiens]
Length = 600
Score = 32.0 bits (71), Expect = 0.65
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W+ +A+ ++ ++ LR +L G R S D +++ +R+ +
Sbjct: 342 WKSLAKLPEFTKSEYAVCALRN------DILVSGGRINSRDVWIYNSQLNIWIRVASLNK 395
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVW 117
R H A + G+ + VVGG+DG RL++V D+ W
Sbjct: 396 G-RWRHKMAVLLGK-VYVVGGYDGQNRLSSVECYDSFSNRW 434
>gi|23397572 kelch-like 34 [Homo sapiens]
Length = 644
Score = 31.2 bits (69), Expect = 1.1
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 15/110 (13%)
Query: 15 WAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGAR 74
W P R+A RA C + R VGGL AGG E + ++D R R A
Sbjct: 405 WTEVPAMREA---RAHFWCGAVGERLLAVGGLGAGG--EVLASVEMYDLRRD---RWTAA 456
Query: 75 GSPPRS-HHDAAPVDGRWLCVVGGW------DGSRRLATVTALDTERGVW 117
G+ PR+ H A V R + + G G+ L + L E VW
Sbjct: 457 GALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVW 506
>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
[Homo sapiens]
Length = 584
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V A+ +R + C E++G Y++GG+ G S + V+DP + L G+
Sbjct: 417 WEVVGNMAV-SRYYFGCCEMQGLIYVIGGISNEGIELRSFE--VYDPLSKRWSPLPPMGT 473
Query: 77 PPRSHHDAAPVDGRWLCV--VGGWDGSR-RLATVTALDTERGVW 117
R++ A ++ C+ VGGW+ ++ L TV E W
Sbjct: 474 -RRAYLGVAALND---CIYSVGGWNETQDALHTVEKYSFEEEKW 513
>gi|223890235 intracisternal A particle-promoted polypeptide isoform
2 [Homo sapiens]
Length = 582
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V A+ +R + C E++G Y++GG+ G S + V+DP + L G+
Sbjct: 417 WEVVGNMAV-SRYYFGCCEMQGLIYVIGGISNEGIELRSFE--VYDPLSKRWSPLPPMGT 473
Query: 77 PPRSHHDAAPVDGRWLCV--VGGWDGSR-RLATVTALDTERGVW 117
R++ A ++ C+ VGGW+ ++ L TV E W
Sbjct: 474 -RRAYLGVAALND---CIYSVGGWNETQDALHTVEKYSFEEEKW 513
>gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens]
Length = 505
Score = 30.4 bits (67), Expect = 1.9
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
+ G + VGG G R + D+ +DP + Q + A RS AA ++G L V
Sbjct: 263 MAGLVFAVGGF-NGSLRVRTVDS--YDPVKDQWTSV-ANMRDRRSTLGAAVLNGL-LYAV 317
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+DGS L++V A + + W
Sbjct: 318 GGFDGSTGLSSVEAYNIKSNEW 339
>gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens]
Length = 597
Score = 30.4 bits (67), Expect = 1.9
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
+ G + VGG G R + D+ +DP + Q + A RS AA ++G L V
Sbjct: 355 MAGLVFAVGGF-NGSLRVRTVDS--YDPVKDQWTSV-ANMRDRRSTLGAAVLNGL-LYAV 409
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+DGS L++V A + + W
Sbjct: 410 GGFDGSTGLSSVEAYNIKSNEW 431
>gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens]
Length = 593
Score = 30.4 bits (67), Expect = 1.9
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
+ G + VGG G R + D+ +DP + Q + A RS AA ++G L V
Sbjct: 351 MAGLVFAVGGF-NGSLRVRTVDS--YDPVKDQWTSV-ANMRDRRSTLGAAVLNGL-LYAV 405
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+DGS L++V A + + W
Sbjct: 406 GGFDGSTGLSSVEAYNIKSNEW 427
>gi|40807500 kelch-like 20 [Homo sapiens]
Length = 609
Score = 30.0 bits (66), Expect = 2.5
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 79 RSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTG 122
RS A V+G+ L VGG+DG+ L T+ D + W + G
Sbjct: 544 RSGVGLAVVNGQ-LMAVGGFDGTTYLKTIEVFDPDANTWRLYGG 586
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 29.6 bits (65), Expect = 3.2
Identities = 31/132 (23%), Positives = 44/132 (33%), Gaps = 26/132 (19%)
Query: 124 PGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCH 183
PG C ++S TCT GG H ++ L + + C+ C
Sbjct: 898 PGTCTDH-VASFTCT--------CPPGYGGFHCEQD--------LPDCSPSSCFNGGTCV 940
Query: 184 TASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKSFLSPQGGTTCCSS 243
S C G H H+ A+P ++ HG + S P TC S
Sbjct: 941 DGVNSFSCLCRPGYTGAHCQHE---------ADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
Query: 244 FDGTACKACEQW 255
F G C+ W
Sbjct: 992 FTGPQCQTLVDW 1003
>gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo
sapiens]
Length = 589
Score = 29.3 bits (64), Expect = 4.2
Identities = 17/50 (34%), Positives = 21/50 (42%)
Query: 85 APVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSS 134
A G L VVGG+ G +R T+ D VW + T P P S
Sbjct: 533 AVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVS 582
>gi|11056006 kelch-like 12 [Homo sapiens]
Length = 568
Score = 29.3 bits (64), Expect = 4.2
Identities = 14/27 (51%), Positives = 18/27 (66%), Gaps = 3/27 (11%)
Query: 94 VVGGWDGSRRLATVTALD---TERGVW 117
V+GG+DG RL++V LD E GVW
Sbjct: 333 VIGGYDGRSRLSSVECLDYTADEDGVW 359
>gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
Length = 875
Score = 28.9 bits (63), Expect = 5.5
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 5/108 (4%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W P+A R F S YL GG+ +G +D + L +R +
Sbjct: 615 WYPLASLPFYDREFFSVVSAGDNIYLSGGMESG---VTLADVWCYMSLLDN-WNLVSRMT 670
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTP 124
PR H++ DG+ + +GG + + V DT WEA P
Sbjct: 671 VPRCRHNSLVYDGK-IYTLGGLGVAGNVDHVERYDTITNQWEAVAPLP 717
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,211,593
Number of Sequences: 37866
Number of extensions: 738449
Number of successful extensions: 1798
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1727
Number of HSP's gapped (non-prelim): 88
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.