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Search of human proteins with 55953106
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor
[Homo sapiens]
(1324 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom... 2858 0.0
gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom... 2856 0.0
gi|110624774 mannose receptor, C type 2 [Homo sapiens] 858 0.0
gi|144446030 lymphocyte antigen 75 [Homo sapiens] 792 0.0
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens] 605 e-173
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens] 604 e-172
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 77 8e-14
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 77 8e-14
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 76 2e-13
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 76 2e-13
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 75 4e-13
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 75 4e-13
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 75 4e-13
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 75 4e-13
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 75 4e-13
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 75 4e-13
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens] 75 4e-13
gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens] 75 5e-13
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 74 7e-13
gi|145275213 coagulation factor XII precursor [Homo sapiens] 73 2e-12
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 70 1e-11
gi|187607300 versican isoform 2 [Homo sapiens] 70 1e-11
gi|21361116 versican isoform 1 [Homo sapiens] 70 1e-11
gi|10835248 regenerating islet-derived 1 beta precursor [Homo sa... 69 4e-11
gi|45580692 C-type lectin domain family 4, member C isoform 2 [H... 69 4e-11
gi|18466806 C-type lectin domain family 4, member C isoform 1 [H... 69 4e-11
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C... 68 5e-11
gi|38372935 brevican isoform 1 [Homo sapiens] 68 7e-11
gi|29725633 regenerating islet-derived 1 alpha precursor [Homo s... 65 4e-10
gi|223029517 CD209 molecule isoform 8 [Homo sapiens] 64 1e-09
>gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo
sapiens]
Length = 1324
Score = 2858 bits (7410), Expect = 0.0
Identities = 1324/1324 (100%), Positives = 1324/1324 (100%)
Query: 1 MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT 60
MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT
Sbjct: 1 MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT 60
Query: 61 LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK 120
LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK
Sbjct: 61 LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK 120
Query: 121 MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF 180
MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF
Sbjct: 121 MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF 180
Query: 181 PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH 240
PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH
Sbjct: 181 PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH 240
Query: 241 ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH 300
ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH
Sbjct: 241 ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH 300
Query: 301 AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH 360
AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH
Sbjct: 301 AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH 360
Query: 361 IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA 420
IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA
Sbjct: 361 IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA 420
Query: 421 EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS 480
EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS
Sbjct: 421 EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS 480
Query: 481 AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS 540
AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS
Sbjct: 481 AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS 540
Query: 541 SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP 600
SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP
Sbjct: 541 SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP 600
Query: 601 VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP 660
VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP
Sbjct: 601 VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP 660
Query: 661 FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE 720
FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE
Sbjct: 661 FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE 720
Query: 721 LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN 780
LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN
Sbjct: 721 LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN 780
Query: 781 KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC 840
KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC
Sbjct: 781 KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC 840
Query: 841 SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD 900
SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD
Sbjct: 841 SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD 900
Query: 901 TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK
Sbjct: 901 TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
Query: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS
Sbjct: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
Query: 1021 VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG 1080
VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG
Sbjct: 1021 VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG 1080
Query: 1081 KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK 1140
KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK
Sbjct: 1081 KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK 1140
Query: 1141 TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD 1200
TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD
Sbjct: 1141 TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD 1200
Query: 1201 EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN 1260
EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN
Sbjct: 1201 EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN 1260
Query: 1261 CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD
Sbjct: 1261 CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
Query: 1321 GNSK 1324
GNSK
Sbjct: 1321 GNSK 1324
>gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo
sapiens]
Length = 1463
Score = 2856 bits (7403), Expect = 0.0
Identities = 1322/1324 (99%), Positives = 1324/1324 (100%)
Query: 1 MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT 60
MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT
Sbjct: 1 MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT 60
Query: 61 LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK 120
LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK
Sbjct: 61 LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK 120
Query: 121 MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF 180
MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF
Sbjct: 121 MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF 180
Query: 181 PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH 240
PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH
Sbjct: 181 PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH 240
Query: 241 ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH 300
ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH
Sbjct: 241 ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH 300
Query: 301 AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH 360
AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH
Sbjct: 301 AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH 360
Query: 361 IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA 420
IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA
Sbjct: 361 IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA 420
Query: 421 EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS 480
EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS
Sbjct: 421 EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS 480
Query: 481 AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS 540
AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS
Sbjct: 481 AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS 540
Query: 541 SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP 600
SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP
Sbjct: 541 SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP 600
Query: 601 VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP 660
VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP
Sbjct: 601 VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP 660
Query: 661 FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE 720
FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE
Sbjct: 661 FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE 720
Query: 721 LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN 780
LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN
Sbjct: 721 LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN 780
Query: 781 KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC 840
KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC
Sbjct: 781 KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC 840
Query: 841 SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD 900
SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD
Sbjct: 841 SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD 900
Query: 901 TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK
Sbjct: 901 TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
Query: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS
Sbjct: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
Query: 1021 VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG 1080
VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG
Sbjct: 1021 VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG 1080
Query: 1081 KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK 1140
KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK
Sbjct: 1081 KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK 1140
Query: 1141 TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD 1200
TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD
Sbjct: 1141 TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD 1200
Query: 1201 EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN 1260
EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN
Sbjct: 1201 EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN 1260
Query: 1261 CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD
Sbjct: 1261 CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
Query: 1321 GNSK 1324
GN++
Sbjct: 1321 GNNE 1324
Score = 146 bits (368), Expect = 1e-34
Identities = 193/787 (24%), Positives = 304/787 (38%), Gaps = 121/787 (15%)
Query: 211 ERDEKWGFCPDPTSAEVGCDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQGGT 266
E +E+W F P C WE + C++ +L +W EA + C+ G
Sbjct: 654 EYEERWPFHP--------CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAH 705
Query: 267 LLSITDETEENFIREHMSSK-----TVEVWMGLNQLDE-HAG-WQWSDGTPLNYLNWSPE 319
L S EENF+ E + SK + W+G N+ + +AG W+WSD TP+ S
Sbjct: 706 LASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVV----SSF 761
Query: 320 VNFEPFVED--HCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATH 377
++ F ED +C + + C S +ICK I ++ K + Y
Sbjct: 762 LDNTYFGEDARNCAVYKA--NKTLLPLHCGSKREWICK-----IPRDVKPKIPFWY---Q 811
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFL---VTLLGDENA 434
+ W Y Y W C +S L+ I S E EF+ + L A
Sbjct: 812 YDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGA 871
Query: 435 SETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCE 494
S WIGL + F W + + VI+ NW T N+SQ C G W + C
Sbjct: 872 S-WWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECS 930
Query: 495 ERLFYICKKAGHVLSDAESG-------CQEGWERHGGFCYKIDTVLRSFDQAS------S 541
+ ICK+ L + + C +GW F YK + D +S +
Sbjct: 931 VSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLY---FNYKCLLLNIPKDPSSWKNWTHA 987
Query: 542 GYYCPP---ALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKP 598
++C LV I + EQAFIT + + + WI LQ ND E TW
Sbjct: 988 QHFCAEEGGTLVAIESEVEQAFITMNLFG----QTTSVWIGLQ--NDDYE-TWL----NG 1036
Query: 599 EPVQYTHWN------------THQPRYSGGCVAMRGR---HPLGRWEVKHCRHFKAMSLC 643
+PV Y++W+ T ++ C + H G+W + C +C
Sbjct: 1037 KPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVC 1096
Query: 644 KQPVENQ-EKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEF 702
++ + + +P P L++ + +K+ ++ TW A C
Sbjct: 1097 EKMQDTSGHGVNTSDMYPM-PNTLEYGNRT-----YKIINANM-----TWYAAIKTCLMH 1145
Query: 703 GAHLASFAHIEEENFVNELLHSKFNWTEERQFWIG-FNKRNPLNAGSWEWSDRTPVVSSF 761
A L S ++F+ +L+ + + WIG F N LN ++WSD T SSF
Sbjct: 1146 KAQLVSITDQYHQSFLTVVLN-RLGYAH----WIGLFTTDNGLN---FDWSDGTK--SSF 1195
Query: 762 LDNTYFGEDARN----CAVYKANKTLLPLHCGSKREW-ICKIPRDVKPKI--PFWYQYDV 814
T++ ++ + C +N C S + IC +P + + + +
Sbjct: 1196 ---TFWKDEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSI 1252
Query: 815 PWLFYQDAEYLFHTFASEWLNFEFV---CSWLHSDLLTIHSAHEQEFIHSKIKALSKYGA 871
PW+ ++ Y F T ++FE C S+LLTI E F+ ++ A
Sbjct: 1253 PWIKFKSNCYSFSTVLDS-MSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQ 1311
Query: 872 SWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSV 931
W+ Q + N+ +W DGTP NW + T + C + GLW C
Sbjct: 1312 MVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQLSPCQE 1371
Query: 932 SMPSICK 938
ICK
Sbjct: 1372 KKGFICK 1378
Score = 129 bits (323), Expect = 2e-29
Identities = 208/951 (21%), Positives = 356/951 (37%), Gaps = 128/951 (13%)
Query: 223 TSAEVGCDTIWEKDLNSHICYQFN-LLSSLSWSEAHSSCQMQGGTLLSITDETEENFIRE 281
+ AE GC WE+ + CY+ + +L S + + C L++IT+ E+ FI
Sbjct: 509 SDAESGCQEGWER--HGGFCYKIDTVLRSFDQASSGYYCPP---ALVTITNRFEQAFITS 563
Query: 282 HMSS----KTVEVWMGLNQLDEHAGWQWSD----GTPLNYLNWSPEVNFEPFVEDHCGTF 333
+SS K W+ L ++ + W P+ Y +W+ +P C
Sbjct: 564 LISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTH---QPRYSGGCVAM 620
Query: 334 SSFMP-SAWRSRDCESTLPY-ICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYK 391
P W + C +CK+ + + + E + W ++ + + P +C+K
Sbjct: 621 RGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYE-ERWPFHPCYLDWESEPGLASCFK 679
Query: 392 LQKEEK-----TWHEALRSCQADNSALIDITSLAEVEFLVTLLGDE----NASETWIGLS 442
+ EK TW EA C+ + L + E F+ LL + + WIG +
Sbjct: 680 VFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFN 739
Query: 443 SNKIPV---SFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFY 499
P+ S+EWS+ + V+ + L+ F ++ C + ++ + +C + +
Sbjct: 740 KRN-PLNAGSWEWSDRTPVVSS---FLDNTYFGEDARNCAVYKANKTLLPL-HCGSKREW 794
Query: 500 ICKKAGHVLSDAESGCQEG--WERHGGFCYKIDTVLR---SFDQASSGYYCPPALVTITN 554
ICK V Q W + Y T +F+ S + L+TI +
Sbjct: 795 ICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSD--LLTIHS 852
Query: 555 RFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYS 614
EQ FI S I ++ K S+ WI LQ++ E+ W+ PV Y +W+T + R
Sbjct: 853 AHEQEFIHSKIKALSKYGASW-WIGLQEERANDEFRWRD----GTPVIYQNWDTGRERTV 907
Query: 615 GGCVAMRG--RHPLGRWEVKHCRHFKAMSLCKQPV-----ENQEKAEYEERWPFHPCYLD 667
G G W + C S+CK+ + ++ + P Y +
Sbjct: 908 NNQSQRCGFISSITGLWGSEECS-VSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLYFN 966
Query: 668 WESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFN 727
++ C + + + W A+ FC E G L + E+ F+ L
Sbjct: 967 YK-------CLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFG--- 1016
Query: 728 WTEERQFWIGFNKRN--------PLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKA 779
+ WIG + P+ +W D + S + T + CA+ +
Sbjct: 1017 --QTTSVWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSH--NTTEVQKHIPLCALLSS 1072
Query: 780 NKTLLPL------HCGSKRE-WICKIPRDVKPK-IPFWYQYDVP-WLFYQDAEYLFHTFA 830
N CG + ++C+ +D + Y +P L Y + Y
Sbjct: 1073 NPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINAN 1132
Query: 831 SEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRD 890
W C + L++I + Q F+ L++ G + WIGL F W D
Sbjct: 1133 MTWYAAIKTCLMHKAQLVSITDQYHQSFL---TVVLNRLGYAHWIGLFTTDNGLNFDWSD 1189
Query: 891 GTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC-SVSMPSICKRKKVWLIEKKK 949
GT + W + + C F S G W S C S +IC V ++
Sbjct: 1190 GTKSSFTFWKDEESSLLGD----CVFADS-NGRWHSTACESFLQGAICH---VPPETRQS 1241
Query: 950 DTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAF 1009
+ P+ W+ F C + D S++ A FC +EG L+ I+ E E AF
Sbjct: 1242 EHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEA---AHEFCKKEGSNLLTIKDEAENAF 1298
Query: 1010 ITMNLFGQTTSV---WIGLQ---NDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKH 1063
+ LF +SV W+ Q N++ W +G P SNW I +T + H
Sbjct: 1299 LLEELFAFGSSVQMVWLNAQFDGNNETIKWFDGTPTDQSNW------GIRKPDTDYFKPH 1352
Query: 1064 IPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYP 1114
+ + G W C +E GF+C+ D ++T++ P
Sbjct: 1353 HCVALRIPE-------GLWQLSPC-QEKKGFICKMEAD-----IHTAEALP 1390
>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
Length = 1479
Score = 858 bits (2218), Expect = 0.0
Identities = 483/1358 (35%), Positives = 715/1358 (52%), Gaps = 85/1358 (6%)
Query: 7 LLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQA-GKSVLTLENCK 65
+LLL L R A G AA P +F+I S L+ C++A G V C
Sbjct: 19 VLLLGCLHLGRPGAPGDAALPEPN---------VFLIFSHGLQGCLEAQGGQVRVTPACN 69
Query: 66 QANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSL--YECDSTLVSLRWRCNRKMIT 123
+ WKWVS + LFN+G CLG + SL YECD ++LRW C T
Sbjct: 70 TSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCR----T 125
Query: 124 GPLQYSVQVAHDNTVVASRKYIHK--------WISYGSGGGDICEYLHKDLHTIKGNTHG 175
Q S+ + + ++ + + W YGS D+C + +++TI+GN+HG
Sbjct: 126 LGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEE-DLCALPYHEVYTIQGNSHG 184
Query: 176 MPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEK 235
PC PF+Y++QW H CT GRED LWCATT Y +DE+WGFCP ++ C+T W+K
Sbjct: 185 KPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSN---DCETFWDK 241
Query: 236 DLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLN 295
D + CYQFN S+LSW EA +SC+ QG LLSIT+ E+ +I ++ + +W+GLN
Sbjct: 242 DQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLN 301
Query: 296 QLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICK 355
LD GWQWSD +PL YLNW + P E++CG + W++RDC LPY+CK
Sbjct: 302 DLDTSGGWQWSDNSPLKYLNWESDQPDNP-SEENCGVIRTESSGGWQNRDCSIALPYVCK 360
Query: 356 KYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALID 415
K N E D W CEP W P+ +CY+LQ E+++W E+ ++C L+
Sbjct: 361 KKPN-ATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVS 419
Query: 416 ITSLAEVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRS 475
I S+AE+EF+ + E E WIGL+ K+ ++FEWS+ S V FT+WH EP+ F +
Sbjct: 420 IHSMAELEFITKQIKQE-VEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSL 478
Query: 476 QLCVSAEQSEGHWKVKNCEERLFYICKKAGHV---LSDAESGCQEGWERHGGFCYKIDTV 532
+ CV+ EG W C + L ICKKAG + ++ + GC++GW H CY +
Sbjct: 479 EDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGED 538
Query: 533 LRSFDQASSGYYCP---PALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEY 589
++ +A C LVTITNRFEQAF++SLI + YFW ALQD N TG +
Sbjct: 539 QVTYSEARR--LCTDHGSQLVTITNRFEQAFVSSLI---YNWEGEYFWTALQDLNSTGSF 593
Query: 590 TWKPVGQKPEPVQYTHWNTHQPRYS-GGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVE 648
W + V YTHWN QP YS GGCVA+ +G WEVK+C F+A +C+Q +
Sbjct: 594 FW----LSGDEVMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLG 649
Query: 649 NQEKAEYEERWP----FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGA 704
E P C W S+ L C+KVF SE++ K++W +A+ C+E GA
Sbjct: 650 TPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGA 709
Query: 705 HLASFAHIEEENFVNELLHSKFNWT-----EERQFWIGFNKRNPLNAGSWEWSDRTPV-V 758
L S A EEE+FV +L+ F + E+ FWIG N+R+P SW WSD
Sbjct: 710 QLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSY 769
Query: 759 SSFLDNTYFGEDARNCAVYK-ANKTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVP-- 815
+F + + +D R CAV A+ + + C ++ +WICKIPR + P D P
Sbjct: 770 HNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREP----DDSPQG 825
Query: 816 ---WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSK-YGA 871
WL +Q+AEY F S W + +C+W ++L ++HS E +F+ ++ S+
Sbjct: 826 RREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQ 885
Query: 872 SWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSV 931
WWIGL ++ FRW DG+ + + +W G+ R V + ++C ++++ WG + C
Sbjct: 886 HWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV-GKDKKCVYMTASREDWGDQRCLT 944
Query: 932 SMPSICKRKKVWLIEKKKDTPKQH-GTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHF 990
++P ICKR V + D P G CP W+ F KC + ++P S W+ AQ
Sbjct: 945 ALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQ-GQEPQSRVKWSEAQFS 1003
Query: 991 CAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYE-TWLNGKPVVYSNWSPFDI 1049
C ++ LV I + +EQAFIT +L T +WIGL + W+ +P++Y+NW+P +
Sbjct: 1004 CEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGE- 1062
Query: 1050 INIPSHNTTEVQKHIPL-CALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVN 1108
PS + + P CA++ +P+ HFTG+W C +E +GF+C+K D S +
Sbjct: 1063 ---PSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS-LSPS 1118
Query: 1109 TSDMYPMPNT-LEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNR 1167
+ + P P T L Y N T++++ + W+ A+ C A L + D Y Q+FLT
Sbjct: 1119 PAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQAARG 1178
Query: 1168 LGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLGDCVFADSNGRWHSTACESFL 1227
L WIGL + + W ++ W+D E G C + D +G W +T+C++ L
Sbjct: 1179 LRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKL 1238
Query: 1228 QGAICHV---PPETRQSEHPELCSE--TSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKK 1282
QGA+C V PP R+ + C + WI F+ +CYSF L + + A + C++
Sbjct: 1239 QGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCYSFHMEL-LLGHKEARQRCQR 1297
Query: 1283 EGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
G +L+I DE EN F+ E L ++ + WL F+
Sbjct: 1298 AGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFN 1335
Score = 218 bits (554), Expect = 4e-56
Identities = 258/1140 (22%), Positives = 436/1140 (38%), Gaps = 174/1140 (15%)
Query: 204 CATTSRYERDEKWGFCPDPT------SAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAH 257
C+ Y +K +PT + +V C+ W+ H CY+ SW E+
Sbjct: 351 CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQP-FQGH-CYRLQA-EKRSWQESK 407
Query: 258 SSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWS 317
+C GG L+SI E FI + + + E+W+GLN L ++WSDG+ +++ +W
Sbjct: 408 KACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWH 467
Query: 318 P--EVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYA 375
P NF +ED C T W C +LP ICKK + E+D
Sbjct: 468 PFEPNNFRDSLED-CVTIWG-PEGRWNDSPCNQSLPSICKK-AGQLSQGAAEEDHG---- 520
Query: 376 THCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENAS 435
C GW ++ +CY L +++ T+ EA R C S L+ IT+ E F+ +L+ +
Sbjct: 521 --CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGE 578
Query: 436 ETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
W L SF W + V++T+W+ +P + + ++ + G W+VKNC
Sbjct: 579 YFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG-YSRGGCVALATGSAMGLWEVKNCTS 637
Query: 496 -RLFYICKKA-GHVLSDAESG----------CQEGW--ERHGGFCYKIDTVLRSFDQAS- 540
R YIC+++ G ++ G C +GW + +CYK+ + R D+ S
Sbjct: 638 FRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSW 697
Query: 541 -----SGYYCPPALVTITNRFEQAFITSLISSVVKMKDS------YFWIALQDQNDTGEY 589
+ L+++ + E+ F+ ++++ + + +FWI L ++ G
Sbjct: 698 VQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQ 757
Query: 590 TWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLG----RWEVKHCRHFKAMSLCKQ 645
+W+ + V +++ N + R+ + RG L +W C + +CK
Sbjct: 758 SWR----WSDGVGFSYHNFDRSRHDDDDI--RGCAVLDLASLQWVAMQC-DTQLDWICKI 810
Query: 646 PVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAH 705
P + + E+E +K F TW +A+ C F A
Sbjct: 811 PRGTDVREPDDSPQGRREWLRFQEAE------YKFFEHHS-----TWAQAQRICTWFQAE 859
Query: 706 LASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLD-- 763
L S E +F++ L KF+ +E+ +WIG + + G + W+D + + +F+
Sbjct: 860 LTSVHSQAELDFLSHNLQ-KFSRAQEQHWWIGLHTSE--SDGRFRWTDGS--IINFISWA 914
Query: 764 ---NTYFGEDARNCAVYKANKTLLPLHCGSKREWICKIPRDVK----PKIPFWYQYDVPW 816
G+D + + + + C + +ICK K P +P P
Sbjct: 915 PGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPS 974
Query: 817 LFYQDAEYLFHTFASE------WLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYG 870
+ Q F E W +F C + L+TI + EQ FI + + ++
Sbjct: 975 DWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT--- 1031
Query: 871 ASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN-----NQSQRCGFI-----SSI 920
WIGL + +F+W + P++Y NW G + N+ C + +
Sbjct: 1032 FDLWIGLHASQR--DFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
Query: 921 TGLWGSEECSVSMPS-ICKR-KKVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDP 978
TG W C+ IC++ L P GT Y N LL P
Sbjct: 1090 TGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGT---ELSYLNGTFRLLQKPL-- 1144
Query: 979 SSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYE---TWLN 1035
W A C +L + QAF+T G T +WIGL ++ +W++
Sbjct: 1145 ----RWHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
Query: 1036 GKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFV 1095
+P+ Y W + +V G W C + G V
Sbjct: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVD------------------GAWRTTSCDTKLQGAV 1242
Query: 1096 CEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTC--------LMHK- 1146
C GV++ P P + Y + + A+ W + C L HK
Sbjct: 1243 C---------GVSSGP--PPPRRISYHGSCPQGL-ADSAWIPFREHCYSFHMELLLGHKE 1290
Query: 1147 ---------AQLVSITDQYHQSFLTVVLNRL---GYAHWIGLFTTDNGLNFDWSDGTKSS 1194
++SI D+ F+ L W+G+ G W D T +
Sbjct: 1291 ARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVN 1350
Query: 1195 FTFWKDEE--SSLLG--DCVFADSN-GRWHSTACESFLQGAICHVPPETRQSEHPELCSE 1249
++ W S+L C + SN G W AC + G +C +P + S P E
Sbjct: 1351 YSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPE 1410
>gi|144446030 lymphocyte antigen 75 [Homo sapiens]
Length = 1722
Score = 792 bits (2045), Expect = 0.0
Identities = 473/1335 (35%), Positives = 684/1335 (51%), Gaps = 100/1335 (7%)
Query: 41 FVIQSESLKKCIQAGKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQP 100
F I + KCI+ + ++C + + LWKWVS H LF++ CLGL+ +
Sbjct: 36 FTIVHGNTGKCIKPVYGWIVADDCDET-EDKLWKWVSQHRLFHLHSQKCLGLDITKSVNE 94
Query: 101 LSLYECDSTLVSLRWRCNRKMITGPLQYSVQVAHDN-TVVASRKYIHKWISYGSGGGDIC 159
L ++ CDS+ + L W+C + G +Y + + + T +++ + K G +C
Sbjct: 95 LRMFSCDSSAM-LWWKCEHHSLYGAARYRLALKDGHGTAISNASDVWK---KGGSEESLC 150
Query: 160 EYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFC 219
+ + +++T GN++G PC FPF + WHH+C + + WCATT YE D KWG C
Sbjct: 151 DQPYHEIYTRDGNSYGRPCEFPFLIDGTWHHDCILD-EDHSGPWCATTLNYEYDRKWGIC 209
Query: 220 PDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFI 279
P E GC+ WEK+ CYQFN ++LSW EA+ SCQ QG LLSI E ++
Sbjct: 210 LKP---ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYL 266
Query: 280 REHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPS 339
+E + W+GLNQL GW+WSD PLN+LNW P+ P +
Sbjct: 267 KEKEGIAKI-FWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESG 325
Query: 340 AWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTW 399
W+S CE+ LPY+C+K LN+ + D W Y T C+ GW P N CY L E +W
Sbjct: 326 LWQSFSCEAQLPYVCRKPLNNT---VELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSW 382
Query: 400 HEALRSCQADNSALIDITSLAEVEFLVTLLGDENASE-TWIGLSSNKIPVSFEWSNDSSV 458
+A C+A +S LI I SLA+VE +VT L +E+ E WIGL + IP F+WS+ + V
Sbjct: 383 DKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEV 442
Query: 459 IFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLSDAESG--C- 515
T W EP++ N++ CVS G WKV++CEE+L Y+CK+ G L+DA S C
Sbjct: 443 TLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMCP 502
Query: 516 -QEGWERHGGFCYKIDTVLRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDS 574
EGW+RHG CYKI D+ G C +TIT+RFEQ ++ L+ K
Sbjct: 503 PDEGWKRHGETCYKIYE-----DEVPFGTNCN---LTITSRFEQEYLNDLMKKYDKSLRK 554
Query: 575 YFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHC 634
YFW L+D + GEY W VG + V +++WN +P GGCVAM +G+WEVK C
Sbjct: 555 YFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVKDC 614
Query: 635 RHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWRE 694
R FKA+S+CK+ + E P PC W+S P SC+KVFH+E+++ KR W E
Sbjct: 615 RSFKALSICKK-MSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEE 673
Query: 695 AEAFCEEFGAHLASFAHIEEENFVNELLHSKFN-WTEERQFWIGFNKRNPLNAGSWEWSD 753
AE FC+ GAHL+SF+H++E + E LH + ++ + WIG NKR+P GSW+WSD
Sbjct: 674 AERFCQALGAHLSSFSHVDE---IKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
Query: 754 RTPVVSSFLDNTYFGE-DARNCAVYKANKT----------------LLPLHCGSKREWIC 796
RTPV + + N + + D R+CA K L P C +K EW+C
Sbjct: 731 RTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC 790
Query: 797 KIPRDVKPKIPFWYQYD-----VPWLFYQDAEYLFHTFASEWLNFE---FVCSWLHSDLL 848
+IP+ PK P WY D P L + +EY F A LN+E C+ HS L
Sbjct: 791 QIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWF--VADLHLNYEEAVLYCASNHSFLA 848
Query: 849 TIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN 908
TI S + I +KI +S G WWI + E +D F + W R
Sbjct: 849 TITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYS------RYPW----HRFPV 898
Query: 909 NQSQRCGFISSIT---GLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLYF 965
+ C ++S+ T L +CS +P IC++ V +EK C + W+ F
Sbjct: 899 TFGEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPF 958
Query: 966 NYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGL 1025
KC L P ++ A C GGTL ++ S++EQ FIT L ++WIGL
Sbjct: 959 QNKCFLKIKPVS----LTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGL 1014
Query: 1026 QNDDYE---TWLNGKPVVYSNWSPFDI---INIPSHNTTEVQKHIPLCALLSSNPNFHFT 1079
+ YE W + + + YSN+ P + + IP + E ++ CAL+ + FT
Sbjct: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRY--HCALILNLQKSPFT 1072
Query: 1080 GKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAI 1139
G W F C + + +C+K + + + T++Y N YKII +TW++A
Sbjct: 1073 GTWNFTSCSERHFVSLCQKYSEVK----SRQTLQNASETVKYLNNLYKIIPKTLTWHSAK 1128
Query: 1140 KTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWK 1199
+ CL QLVSITD Y Q+FL+V + WIGLF+ D+ LNF WSDG + F+ W
Sbjct: 1129 RECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA 1188
Query: 1200 DEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCS------ETSIP 1253
E + L DCV D++G W + C GAIC+ + E + S + P
Sbjct: 1189 -ETNGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
Query: 1254 WIKFKSNCYSFSTVLD---SMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGS 1308
WI F++ CY+F + + + + H C+K S++L+I+DE EN F+LE+L F
Sbjct: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
Query: 1309 SVQMVWLNAQFDGNS 1323
V L + S
Sbjct: 1308 MASWVMLGITYRNKS 1322
Score = 150 bits (379), Expect = 8e-36
Identities = 255/1104 (23%), Positives = 426/1104 (38%), Gaps = 181/1104 (16%)
Query: 229 CDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQGGTLLSIT--DETEE--NFIR 280
C W+ S CY+ ++ +W EA CQ G L S + DE +E +F+
Sbjct: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
Query: 281 EHMSSKTVEVWMGLNQL--DEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP 338
+ S + +W+GLN+ D WQWSD TP++ + E + + D C F
Sbjct: 703 DQFSGQHW-LWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD-CAAVKVFH- 759
Query: 339 SAWR-------SRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW-NPYNRNCY 390
WR R+ P+ C L + + K T P W NP +
Sbjct: 760 RPWRRGWHFYDDREFIYLRPFACDTKLEWVCQ--IPKGR-----TPKTPDWYNPDRAGIH 812
Query: 391 K---LQKEEKTW---------HEALRSCQADNSALIDITSLAEVEFLVTLLGD--ENASE 436
+ + + W EA+ C +++S L ITS ++ + + + + +
Sbjct: 813 GPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQK 872
Query: 437 TWIGLSSNKIPVSFEWSNDSSVIFTN--WHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCE 494
WI +S EW D ++ WH P F + K +C
Sbjct: 873 WWIRIS--------EWPIDDHFTYSRYPWHRF-PVTFGEECLYMSAKTWLIDLGKPTDCS 923
Query: 495 ERLFYICKKAGHVL-------SDAESGCQEGWERHGGFCY-KIDTVLRSFDQASSGYYC- 545
+L +IC+K S A+ C E W C+ KI V +F QAS +
Sbjct: 924 TKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSY 983
Query: 546 PPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTH 605
L ++ ++ EQ FITSL+ + ++ WI L+ ++ + + + + T+
Sbjct: 984 GGTLPSVLSQIEQDFITSLLPDM----EATLWIGLRWT------AYEKINKWTDNRELTY 1033
Query: 606 WNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPC- 664
N H SG R R P +E + R+ A+ L N +K+ + W F C
Sbjct: 1034 SNFHPLLVSG-----RLRIPENFFE-EESRYHCALIL------NLQKSPFTGTWNFTSCS 1081
Query: 665 ----------YLDWESEPGLASCFKVF----HSEKVLMKR-TWREAEAFCEEFGAHLASF 709
Y + +S L + + + K++ K TW A+ C + L S
Sbjct: 1082 ERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSI 1141
Query: 710 AHIEEENF--VNELLHSKFNWTEERQFWIG-FNKRNPLNAGSWEWSDRTPVVSSFLDNTY 766
++ F V LLH+ WIG F++ + LN G WSD + S T
Sbjct: 1142 TDPYQQAFLSVQALLHNS-------SLWIGLFSQDDELNFG---WSDGKRLHFSRWAET- 1190
Query: 767 FGEDARNCAVYKANKTLLPLHCGSKREW-IC-----KIPRDVKP----KIPFWYQYDVPW 816
+C V + + C + IC + ++VKP K P + PW
Sbjct: 1191 -NGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPV-LNTPW 1248
Query: 817 LFYQDAEYLF-----HTFASEWLNFEFVCSWLH--SDLLTIHSAHEQEFIHSKIKALSKY 869
+ +Q+ Y F A+ C L+ S +L+I E F+ ++ + Y
Sbjct: 1249 IPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFN-Y 1307
Query: 870 GASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC 929
ASW + L N W D TP+ Y +W GR T+ N+ G S G W +
Sbjct: 1308 MASW-VMLGITYRNKSLMWFDKTPLSYTHWRAGRP-TIKNEKFLAGL--STDGFWDIQTF 1363
Query: 930 SVSMPSICKRK------KVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKN 983
V ++ + K+ +++ K++ + T P+ + Y+ + ++ + +W
Sbjct: 1364 KVIEEAVYFHQHSILACKIEMVDYKEE---YNTTLPQ---FMPYEDGIYSVIQKKVTWYE 1417
Query: 984 WTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYETWLNGKPVVYSN 1043
A + C++ GG L ++ ++ Q F+ + +W+GL + D +S+
Sbjct: 1418 ---ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSE----SSFEWSD 1470
Query: 1044 WSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTS 1103
S FD I P T C LL G W E C G +C K +
Sbjct: 1471 GSTFDYI--PWKGQTSPGN----CVLLDPK------GTWKHEKCNSVKDGAICYKPTKSK 1518
Query: 1104 GHGVNT-SDMYPMPNT-----LEYGNRTYKIINANMTWYAAIKTCLMH--KAQLVSITDQ 1155
T S P ++Y YK A ++ A K C H A +VSI D+
Sbjct: 1519 KLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDE 1578
Query: 1156 YHQSFLTVVL---NRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLGDC-VF 1211
F++ ++ N + W+GL ++ W DG++ +F W+++ S +G C +
Sbjct: 1579 DENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSML 1638
Query: 1212 ADSNGRWHSTACESFLQGAICHVP 1235
SN W CE +C VP
Sbjct: 1639 IASNETWKKVECEHGFGRVVCKVP 1662
Score = 143 bits (360), Expect = 1e-33
Identities = 165/726 (22%), Positives = 282/726 (38%), Gaps = 99/726 (13%)
Query: 634 CRHFKAMSLCKQPVENQEKAEYEERW-PF-HPCYLDWESEPGLASCFKVFHSEKVLMKRT 691
C + SL K ++ K + E+W PF + C+L + + T
Sbjct: 930 CEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKP-----------------VSLT 972
Query: 692 WREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEW 751
+ +A C +G L S E++F+ LL E WIG W
Sbjct: 973 FSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDM-----EATLWIGLRWTAYEKINKWT- 1026
Query: 752 SDRTPVVSSF----------LDNTYFGEDARNCAVYKANKTLLPL-------HCGSKREW 794
+R S+F + +F E++R N P C S+R +
Sbjct: 1027 DNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC-SERHF 1085
Query: 795 ICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAH 854
+ + + K Q + Y + Y W + + C + L++I +
Sbjct: 1086 VSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPY 1145
Query: 855 EQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC 914
+Q F+ ++AL + +S WIGL + F W DG + + W N Q + C
Sbjct: 1146 QQAFL--SVQALL-HNSSLWIGLFSQDDELNFGWSDGKRLHFSRW-----AETNGQLEDC 1197
Query: 915 GFISSITGLWGSEECSVSMP-SICKRKKVWLIEKKKDTPKQHGTCPKG-----WLYFNYK 968
+ + G W + +C+ + P +IC +K+ P CP W+ F
Sbjct: 1198 VVLDT-DGFWKTVDCNDNQPGAICYYSGNET--EKEVKPVDSVKCPSPVLNTPWIPFQNC 1254
Query: 969 CLLLNIPKDP--SSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNL-FGQTTSVWIGL 1025
C I K+ ++ ++ H + +++I E E F+ L + + W+ L
Sbjct: 1255 CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVML 1314
Query: 1026 ---QNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKW 1082
+ W + P+ Y++W T + +K + A LS++ G W
Sbjct: 1315 GITYRNKSLMWFDKTPLSYTHWRA-------GRPTIKNEKFL---AGLSTD------GFW 1358
Query: 1083 YFEDCG--KEGYGFVCEKMQDTSGHGVNTSDMY--PMPNTLEYGNRTYKIINANMTWYAA 1138
+ +E F + V+ + Y +P + Y + Y +I +TWY A
Sbjct: 1359 DIQTFKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEA 1418
Query: 1139 IKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNG-LNFDWSDGTKSSFTF 1197
+ C L S+ +Q Q FL ++ R G+ W+GL + D +F+WSDG+ +
Sbjct: 1419 LNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIP 1478
Query: 1198 WKDEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQ------SEHPELCSETS 1251
WK + S G+CV D G W C S GAIC+ P ++++ S E
Sbjct: 1479 WKGQTSP--GNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENG 1536
Query: 1252 IPWIKFKSNCYSFSTVLDSMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGSS 1309
WI++K +CY L SF A + C K + +++IKDE EN F+ + +
Sbjct: 1537 SRWIQYKGHCYKSDQALH--SFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNI 1594
Query: 1310 VQMVWL 1315
VWL
Sbjct: 1595 TMRVWL 1600
Score = 89.7 bits (221), Expect = 2e-17
Identities = 108/458 (23%), Positives = 180/458 (39%), Gaps = 62/458 (13%)
Query: 219 CPDPTSAEVGCDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQG--GTLLSITD 272
CP P +T W N CY F N + + E H+ CQ +LSI D
Sbjct: 1239 CPSPV-----LNTPWIPFQNC--CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRD 1291
Query: 273 ETEENFIREHMSS-KTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWS---PEVNFEPFVED 328
E E NF+ E + + W+ L + W D TPL+Y +W P + E F+
Sbjct: 1292 EKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFL-- 1349
Query: 329 HCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRN 388
G + + E + Y + + E+V+ +K P + PY
Sbjct: 1350 -AGLSTDGFWDIQTFKVIEEAV-YFHQHSILACKIEMVD---YKEEYNTTLPQFMPYEDG 1404
Query: 389 CYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNK-IP 447
Y + +++ TW+EAL C L + + FL ++ + W+GLSS+
Sbjct: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIV-KRDGFPLWVGLSSHDGSE 1463
Query: 448 VSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE-RLFYICKK--- 503
SFEWS+ S+ + W + P CV + +G WK + C + IC K
Sbjct: 1464 SSFEWSDGSTFDYIPW---KGQTSPGN---CVLLD-PKGTWKHEKCNSVKDGAICYKPTK 1516
Query: 504 ---------AGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS---SGYYCPPALVT 551
+ + E+G + W ++ G CYK D L SF +A S + +V+
Sbjct: 1517 SKKLSRLTYSSRCPAAKENGSR--WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVS 1574
Query: 552 ITNRFEQAFITSLI--SSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTH 609
I + E F++ L+ ++ + M+ W+ L + ++W + V + W
Sbjct: 1575 IKDEDENKFVSRLMRENNNITMR---VWLGLSQHSVDQSWSWLDGSE----VTFVKWENK 1627
Query: 610 QPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPV 647
G C + + W+ C H +CK P+
Sbjct: 1628 SKSGVGRCSMLIASNE--TWKKVECEHGFGRVVCKVPL 1663
>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
Length = 1456
Score = 605 bits (1560), Expect = e-173
Identities = 389/1297 (29%), Positives = 615/1297 (47%), Gaps = 77/1297 (5%)
Query: 41 FVIQSESLKKCIQA-GKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQ 99
F+I +E K+C+ A S + C Q + ++WVS + ++ CLG+
Sbjct: 25 FLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWV 84
Query: 100 PLSLYECDSTLVSLRWRCNRKMITGP------LQYSVQVAHDNTVVASRKYIHKWISYGS 153
++LY CDS +W C + G Y + + + +W YG+
Sbjct: 85 AITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGT 144
Query: 154 GGGDICEYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERD 213
++C ++ ++T+ GN +G C FPF++ ++W+ +CT GR D LWC TT+ Y+ D
Sbjct: 145 -TDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTD 203
Query: 214 EKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDE 273
+ +G+CP G +++W KD + + YQ N S+L+W +A SCQ Q LLSIT+
Sbjct: 204 KLFGYCPLKFE---GSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEI 260
Query: 274 TEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSP-EVNFEPFVEDHCGT 332
E+ ++ SS T +W+GLN L ++GWQWSD +P YLNW P + EP C +
Sbjct: 261 HEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEP--GKSCVS 318
Query: 333 FSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKL 392
+ + W + +C L YICKK ++ ++ ++ THC W PY +CYK+
Sbjct: 319 LNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSES--DVPTHCPSQWWPYAGHCYKI 376
Query: 393 QKEE-KTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNKIPVSFE 451
++E K +AL +C+ + S L I ++ E +F+++ LG E E WIGL+ KI + FE
Sbjct: 377 HRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDELWIGLNDIKIQMYFE 436
Query: 452 WSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK----KAGHV 507
WS+ + V FT W EP NR + CV + +G+W + CE L YICK G
Sbjct: 437 WSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPE 496
Query: 508 LSDAESGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLIS 566
+ + E GC++GW++H +CY I L +F +A+ A L TI +R+EQAF+TS +
Sbjct: 497 IVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVG 556
Query: 567 SVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPL 626
+ YFW L D G + W E V++THWN+ P GCVAMR
Sbjct: 557 ---LRPEKYFWTGLSDIQTKGTFQW----TIEEEVRFTHWNSDMPGRKPGCVAMRTGIAG 609
Query: 627 GRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKV 686
G W+V C KA +CK E P C DW + + CFK++ K
Sbjct: 610 GLWDVLKCDE-KAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGK- 667
Query: 687 LMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNA 746
K+TW E+ FC G LAS + EE+ + L+ + ++ + FW+G +P +
Sbjct: 668 HEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSY--HKLFWLGLTYGSP--S 723
Query: 747 GSWEWSDRTPVVSSFLDNTYFGE-----DARNCAVYKANKTLL--PLHCGSKREWICKIP 799
+ WSD +PV +N +GE + C K + T+ ++C WIC+I
Sbjct: 724 EGFTWSDGSPV---SYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQ 780
Query: 800 RDVKPK-IPFWYQYDVP------WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHS 852
+ PK P D P W+ Y+D +Y F N C DL++I S
Sbjct: 781 KGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQS 840
Query: 853 AHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQ 912
E++F+ + A ++IGL + +F W DG+ V Y +W TG E N+ +
Sbjct: 841 ESEKKFLWKYVNRNDAQSA-YFIGLLIS-LDKKFAWMDGSKVDYVSWATG-EPNFANEDE 897
Query: 913 RCGFISSITGLWGSEECSVSMPSICKR--KKVWLIEKKKDTPKQHGTCPKGWLYFNYKCL 970
C + S +G W C IC+R + P C +GW +++ KC
Sbjct: 898 NCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCF 957
Query: 971 LLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDY 1030
+ KNW A+ C GG LV+I++E EQAF+T ++ T S W GL + +
Sbjct: 958 KI-FGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNS 1016
Query: 1031 E---TWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDC 1087
E W +G+ V Y+NW P + + C ++ + + GKW + C
Sbjct: 1017 EHTFLWTDGRGVHYTNWGK----GYPGGRRSSLSYEDADCVVIIGGAS-NEAGKWMDDTC 1071
Query: 1088 GKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKA 1147
+ G++C+ D S N ++YG +Y ++ W+ A C +H +
Sbjct: 1072 DSK-RGYICQTRSDPS--LTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNS 1128
Query: 1148 QLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLG 1207
+ SI D Y +F + + WI L + + W+D + +T W +E L
Sbjct: 1129 LIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKS 1188
Query: 1208 DCVFADSNGRWHSTAC-ESFLQGAICHVPPETRQSEHPEL---CSETS-IPWIKFKSNCY 1262
CV+ D +G W + C ESF +C E +E P+L C E+ WI F +CY
Sbjct: 1189 ACVYLDLDGYWKTAHCNESFY--FLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCY 1246
Query: 1263 SFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFL 1299
+ +A+ E C + GS+L++I+ AE++FL
Sbjct: 1247 YIESSYTRNWGQASLE-CLRMGSSLVSIESAAESSFL 1282
Score = 212 bits (539), Expect = 2e-54
Identities = 252/1072 (23%), Positives = 402/1072 (37%), Gaps = 164/1072 (15%)
Query: 242 CYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSK-TVEVWMGLNQLDEH 300
CY+ + +A ++C+ +G L SI E +FI + + E+W+GLN +
Sbjct: 373 CYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDELWIGLNDIKIQ 432
Query: 301 AGWQWSDGTPLNYLNW-SPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLN 359
++WSDGTP+ + W E + E ++ C W R CE L YICK
Sbjct: 433 MYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKG-KDGYWADRGCEWPLGYICKMKSR 491
Query: 360 HIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSL 419
EIVE + C GW ++ CY + T+ EA ++C +N+ L I
Sbjct: 492 SQGPEIVEVEKG------CRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDR 545
Query: 420 AEVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCV 479
E FL + +G W GLS + +F+W+ + V FT+W++ P R CV
Sbjct: 546 YEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNS----DMPGRKPGCV 601
Query: 480 SAEQ--SEGHWKVKNCEERLFYICKKAGHVLSDA-------ESGCQEGW--ERHGGFCYK 528
+ + G W V C+E+ ++CK ++ E C E W C+K
Sbjct: 602 AMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFK 661
Query: 529 IDTV----------LRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDSY--- 575
+ R F +A G L +I N+ EQ I LI++ SY
Sbjct: 662 LYAKGKHEKKTWFESRDFCRALGG-----DLASINNKEEQQTIWRLITA----SGSYHKL 712
Query: 576 FWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGG---CVAMRGRHPLGRWEVK 632
FW+ L + + +TW PV Y +W +P C ++G P W
Sbjct: 713 FWLGLTYGSPSEGFTWSD----GSPVSYENWAYGEPNNYQNVEYCGELKG-DPTMSWNDI 767
Query: 633 HCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLM---K 689
+C H +C+ K E P ++ P + ++ + K
Sbjct: 768 NCEHLNNW-ICQIQKGQTPKPE--------PTPAPQDNPPVTEDGWVIYKDYQYYFSKEK 818
Query: 690 RTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGF----NKRNPLN 745
T A AFC+ L S E+ F+ + ++ + ++IG +K+
Sbjct: 819 ETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRN---DAQSAYFIGLLISLDKKF--- 872
Query: 746 AGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKANKTLL-PLHCGSKREWICKIPRD--- 801
+W + VS F + NC +N ++CG +IC+
Sbjct: 873 --AWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSIN 930
Query: 802 ---VKPKIPFWYQYDVP------WLFYQDAEYLFHTFASE----WLNFEFVCSWLHSDLL 848
V P +P VP W FY + + F E W C +L+
Sbjct: 931 ATTVMPTMP-----SVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLV 985
Query: 849 TIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTG----RE 904
+I + EQ F+ +K S + A W GL + + F W DG V Y NW G R
Sbjct: 986 SIQNEKEQAFLTYHMKD-STFSA--WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRR 1042
Query: 905 RTVNNQSQRC----GFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
+++ + C G S+ G W + C IC+ + + T + G
Sbjct: 1043 SSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKY 1102
Query: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
G +Y + W A+ +C + +I AF + +
Sbjct: 1103 G--KSSYSLMRQKF--------QWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNER 1152
Query: 1021 VWIGLQN---DDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFH 1077
VWI L + D+ TW + V Y+NW+ + K C L +
Sbjct: 1153 VWIALNSNLTDNQYTWTDKWRVRYTNWA------------ADEPKLKSACVYLDLD---- 1196
Query: 1078 FTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKI--------I 1129
G W C + Y F+C++ + + ++ +P + T I I
Sbjct: 1197 --GYWKTAHCNESFY-FLCKRSDE-----IPATEPPQLPGRCPESDHTAWIPFHGHCYYI 1248
Query: 1130 NANMT--WYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYA--HWIGLFTTDNGLNF 1185
++ T W A CL + LVSI SFL+ + L WIGLF G +
Sbjct: 1249 ESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEG-TW 1307
Query: 1186 DWSDGTKSSFTFWK-DEESSLLGDCV-FADSNGRWHSTACESFLQGAICHVP 1235
W + + SF W + S DCV S+G W + C S+ +G IC P
Sbjct: 1308 LWINNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCSSY-KGYICKRP 1358
Score = 184 bits (468), Expect = 4e-46
Identities = 197/793 (24%), Positives = 312/793 (39%), Gaps = 97/793 (12%)
Query: 220 PDPTSA-EVGCDTIWEKDLNSHICYQFNLLSS---LSWSEAHSSCQMQGGTLLSITDETE 275
P PT+ E C W + +C++ +W E+ C+ GG L SI ++ E
Sbjct: 636 PKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEE 695
Query: 276 ENFIREHMSSKTVE---VWMGLNQLDEHAGWQWSDGTPLNYLNWS-PEVNFEPFVEDHCG 331
+ I +++ W+GL G+ WSDG+P++Y NW+ E N VE +CG
Sbjct: 696 QQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVE-YCG 754
Query: 332 TFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYK 391
+W +CE +IC+ A + E GW Y Y
Sbjct: 755 ELKGDPTMSWNDINCEHLNNWICQIQKGQTPKP-EPTPAPQDNPPVTEDGWVIYKDYQYY 813
Query: 392 LQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETW-IGLSSNKIPVSF 450
KE++T A C+ + L+ I S +E +FL + +A + IGL + + F
Sbjct: 814 FSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLIS-LDKKF 872
Query: 451 EWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLS- 509
W + S V + +W T EP+ F N + CV+ + G W NC +IC++ ++
Sbjct: 873 AWMDGSKVDYVSWATGEPN-FANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINA 931
Query: 510 --------DAESGCQEGWERHGGFCYKI----DTVLRSFDQASSGYY-CPPALVTITNRF 556
SGC+EGW + C+KI + +++ +A LV+I N
Sbjct: 932 TTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEK 991
Query: 557 EQAFITSLISSVVKMKDSYF--WIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR-- 612
EQAF+T MKDS F W L D N + W V YT+W P
Sbjct: 992 EQAFLT------YHMKDSTFSAWTGLNDVNSEHTFLWTD----GRGVHYTNWGKGYPGGR 1041
Query: 613 ------YSGGCVAMRG--RHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPC 664
CV + G + G+W C K +C Q +++ P
Sbjct: 1042 RSSLSYEDADCVVIIGGASNEAGKWMDDTCDS-KRGYIC------QTRSDPSLTNPPATI 1094
Query: 665 YLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHS 724
D + G +S + K W EAE +C+ + +AS + + N
Sbjct: 1095 QTDGFVKYGKSSY------SLMRQKFQWHEAETYCKLHNSLIASIL----DPYSNAFAWL 1144
Query: 725 KFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARN----CAVYKAN 780
+ + ER WI N L + W+D+ V T + D C +
Sbjct: 1145 QMETSNER-VWIALNSN--LTDNQYTWTDKWRV-----RYTNWAADEPKLKSACVYLDLD 1196
Query: 781 KTLLPLHCGSKREWICK----IPRDVKPKIPFWYQYD--VPWL-FYQDAEYLFHTFASEW 833
HC ++CK IP P++P W+ F+ Y+ ++ W
Sbjct: 1197 GYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNW 1256
Query: 834 LNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTP 893
C + S L++I SA E F+ +++ L K ++WIGL + W + +P
Sbjct: 1257 GQASLECLRMGSSLVSIESAAESSFLSYRVEPL-KSKTNFWIGLFRN-VEGTWLWINNSP 1314
Query: 894 VIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKV-------WLIE 946
V + NW+TG N C + + +G W + CS ICKR K+ L+
Sbjct: 1315 VSFVNWNTGDPSGERND---CVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLT 1371
Query: 947 KKKDTPKQHGTCP 959
K DT K + P
Sbjct: 1372 TKADTRKMDPSKP 1384
Score = 179 bits (455), Expect = 1e-44
Identities = 201/879 (22%), Positives = 345/879 (39%), Gaps = 99/879 (11%)
Query: 220 PDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFI 279
P+ E GC W+K + CY S +++EA+ +C + L +I D E+ F+
Sbjct: 495 PEIVEVEKGCRKGWKK--HHFYCYMIGHTLS-TFAEANQTCNNENAYLTTIEDRYEQAFL 551
Query: 280 REHMSSKTVEV-WMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP 338
+ + + W GL+ + +QW+ + + +W+ ++ P + C + +
Sbjct: 552 TSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDM---PGRKPGCVAMRTGIA 608
Query: 339 SA-WRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRN--CYKL--- 392
W C+ ++CK + + H + C W +R C+KL
Sbjct: 609 GGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPE---PKCPEDWGASSRTSLCFKLYAK 665
Query: 393 -QKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET--WIGLSSNKIPVS 449
+ E+KTW E+ C+A L I + E + + L+ + W+GL+
Sbjct: 666 GKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEG 725
Query: 450 FEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK------- 502
F WS+ S V + NW EP+ + N W NCE +IC+
Sbjct: 726 FTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTP 785
Query: 503 --KAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA---LVTITNRFE 557
+ D ++GW + + Y + D A + +C LV+I + E
Sbjct: 786 KPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARA--FCKRNFGDLVSIQSESE 843
Query: 558 QAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSG-- 615
+ F+ ++ S ++I L D ++ W G K V Y W T +P ++
Sbjct: 844 KKFLWKYVNR--NDAQSAYFIGLLISLDK-KFAWMD-GSK---VDYVSWATGEPNFANED 896
Query: 616 -GCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHP--CYLDWESEP 672
CV M G W +C + A +C++ + P P C W
Sbjct: 897 ENCVTMYSNS--GFWNDINCGYPNAF-ICQRHNSSINATTVMPTMPSVPSGCKEGWNFYS 953
Query: 673 GLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVN-ELLHSKFNWTEE 731
CFK+F + ++ W+EA C FG +L S + +E+ F+ + S F+
Sbjct: 954 N--KCFKIFGFMEE-ERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFS---- 1006
Query: 732 RQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFG--------EDARNCAVY------ 777
W G N N + ++ W+D V + Y G EDA +C V
Sbjct: 1007 --AWTGLNDVN--SEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDA-DCVVIIGGASN 1061
Query: 778 KANKTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFE 837
+A K + C SKR +IC+ D P ++ Y + Y +W E
Sbjct: 1062 EAGKWMDDT-CDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAE 1120
Query: 838 FVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQ 897
C +S + +I + F +++ ++ WI L ++++ W D V Y
Sbjct: 1121 TYCKLHNSLIASILDPYSNAFAWLQMETSNE---RVWIALNSNLTDNQYTWTDKWRVRYT 1177
Query: 898 NWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGT 957
NW + C ++ + G W + C+ S +CKR + P+ G
Sbjct: 1178 NWAADEPKL----KSACVYLD-LDGYWKTAHCNESFYFLCKRSDEI---PATEPPQLPGR 1229
Query: 958 CPKG----WLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMN 1013
CP+ W+ F+ C + + S +NW A C G +LV+IES E +F++
Sbjct: 1230 CPESDHTAWIPFHGHCYYI----ESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYR 1285
Query: 1014 L--FGQTTSVWIGLQNDDYETWL--NGKPVVYSNWSPFD 1048
+ T+ WIGL + TWL N PV + NW+ D
Sbjct: 1286 VEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGD 1324
Score = 113 bits (283), Expect = 1e-24
Identities = 123/521 (23%), Positives = 198/521 (38%), Gaps = 59/521 (11%)
Query: 830 ASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWR 889
A W C +++LL+I HEQ ++ +L+ + WIGL N ++W
Sbjct: 237 ALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLT---SGLWIGLNSLSFNSGWQWS 293
Query: 890 DGTPVIYQNWDTGRERTVNNQSQRCGFIS-SITGLWGSEECSVSMPSICKRKKVWL---- 944
D +P Y NW G +S C ++ W + EC + ICK+ L
Sbjct: 294 DRSPFRYLNWLPGSPSAEPGKS--CVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFV 351
Query: 945 IEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESE 1004
I + D P CP W + C I +D K A C +EG L +I +
Sbjct: 352 IPSESDVPTH---CPSQWWPYAGHCY--KIHRDEK--KIQRDALTTCRKEGSDLASIHTI 404
Query: 1005 VEQAFITMNL-FGQTTSVWIGLQN---DDYETWLNGKPVVYSNWSPFDIINIPSHNTTEV 1060
E FI L + +WIGL + Y W +G PV ++ W + PSH
Sbjct: 405 EEFDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKW----LRGEPSHENNRQ 460
Query: 1061 QKHIPLCALLSSNPNFHFTGKWYFEDCGKEG-YGFVCEKMQDTSGHGVNTSDMYPMPNTL 1119
+ C ++ Y+ D G E G++C+ + G + +
Sbjct: 461 ED----CVVMKGKDG-------YWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWK 509
Query: 1120 EYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLN-RLGYAHWIGLFT 1178
++ Y I + T+ A +TC A L +I D+Y Q+FLT + R W GL
Sbjct: 510 KHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSD 569
Query: 1179 TDNGLNFDWSDGTKSSFTFWKDEESSLLGDCVFADSN---GRWHSTACESFLQ------- 1228
F W+ + FT W + CV + G W C+ +
Sbjct: 570 IQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWA 629
Query: 1229 GAICHVP-----PETRQSEHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKE 1283
+ H P PE + E S TS+ + + + T +S +FC+
Sbjct: 630 EGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFES------RDFCRAL 683
Query: 1284 GSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFDGNSK 1324
G +L +I ++ E + + A GS ++ WL + S+
Sbjct: 684 GGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSE 724
>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
Length = 1456
Score = 604 bits (1558), Expect = e-172
Identities = 388/1297 (29%), Positives = 615/1297 (47%), Gaps = 77/1297 (5%)
Query: 41 FVIQSESLKKCIQA-GKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQ 99
F+I +E K+C+ A S + C Q + ++WVS + ++ CLG+
Sbjct: 25 FLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWV 84
Query: 100 PLSLYECDSTLVSLRWRCNRKMITGP------LQYSVQVAHDNTVVASRKYIHKWISYGS 153
++LY CDS +W C + G Y + + + +W YG+
Sbjct: 85 AITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGT 144
Query: 154 GGGDICEYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERD 213
++C ++ ++T+ GN +G C FPF++ ++W+ +CT GR D LWC TT+ Y+ D
Sbjct: 145 -TDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTD 203
Query: 214 EKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDE 273
+ +G+CP G +++W KD + + YQ N S+L+W +A SCQ Q LLSIT+
Sbjct: 204 KLFGYCPLKFE---GSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEI 260
Query: 274 TEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSP-EVNFEPFVEDHCGT 332
E+ ++ SS T +W+GLN L ++GWQWSD +P YLNW P + EP C +
Sbjct: 261 HEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEP--GKSCVS 318
Query: 333 FSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKL 392
+ + W + +C L YICKK ++ ++ ++ THC W PY +CYK+
Sbjct: 319 LNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSES--DVPTHCPSQWWPYAGHCYKI 376
Query: 393 QKEE-KTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNKIPVSFE 451
++E K +AL +C+ + L I ++ E++F+++ LG E E WIGL+ KI + FE
Sbjct: 377 HRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFE 436
Query: 452 WSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK----KAGHV 507
WS+ + V FT W EP NR + CV + +G+W + CE L YICK G
Sbjct: 437 WSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPE 496
Query: 508 LSDAESGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLIS 566
+ + E GC++GW++H +CY I L +F +A+ A L TI +R+EQAF+TS +
Sbjct: 497 IVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVG 556
Query: 567 SVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPL 626
+ YFW L D G + W E V++THWN+ P GCVAMR
Sbjct: 557 ---LRPEKYFWTGLSDIQTKGTFQW----TIEEEVRFTHWNSDMPGRKPGCVAMRTGIAG 609
Query: 627 GRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKV 686
G W+V C KA +CK E P C DW + + CFK++ K
Sbjct: 610 GLWDVLKCDE-KAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGK- 667
Query: 687 LMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNA 746
K+TW E+ FC G LAS + EE+ + L+ + ++ + FW+G +P +
Sbjct: 668 HEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSY--HKLFWLGLTYGSP--S 723
Query: 747 GSWEWSDRTPVVSSFLDNTYFGE-----DARNCAVYKANKTLL--PLHCGSKREWICKIP 799
+ WSD +PV +N +GE + C K + T+ ++C WIC+I
Sbjct: 724 EGFTWSDGSPV---SYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQ 780
Query: 800 RDVKPK-IPFWYQYDVP------WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHS 852
+ PK P D P W+ Y+D +Y F N C DL++I S
Sbjct: 781 KGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQS 840
Query: 853 AHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQ 912
E++F+ + A ++IGL + +F W DG+ V Y +W TG E N+ +
Sbjct: 841 ESEKKFLWKYVNRNDAQSA-YFIGLLIS-LDKKFAWMDGSKVDYVSWATG-EPNFANEDE 897
Query: 913 RCGFISSITGLWGSEECSVSMPSICKR--KKVWLIEKKKDTPKQHGTCPKGWLYFNYKCL 970
C + S +G W C IC+R + P C +GW +++ KC
Sbjct: 898 NCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCF 957
Query: 971 LLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDY 1030
+ KNW A+ C GG LV+I++E EQAF+T ++ T S W GL + +
Sbjct: 958 KI-FGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNS 1016
Query: 1031 E---TWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDC 1087
E W +G+ V Y+NW P + + C ++ + + GKW + C
Sbjct: 1017 EHTFLWTDGRGVHYTNWGK----GYPGGRRSSLSYEDADCVVIIGGAS-NEAGKWMDDTC 1071
Query: 1088 GKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKA 1147
+ G++C+ D S N ++YG +Y ++ W+ A C +H +
Sbjct: 1072 DSK-RGYICQTRSDPS--LTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNS 1128
Query: 1148 QLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLG 1207
+ SI D Y +F + + WI L + + W+D + +T W +E L
Sbjct: 1129 LIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKS 1188
Query: 1208 DCVFADSNGRWHSTAC-ESFLQGAICHVPPETRQSEHPEL---CSETS-IPWIKFKSNCY 1262
CV+ D +G W + C ESF +C E +E P+L C E+ WI F +CY
Sbjct: 1189 ACVYLDLDGYWKTAHCNESFY--FLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCY 1246
Query: 1263 SFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFL 1299
+ +A+ E C + GS+L++I+ AE++FL
Sbjct: 1247 YIESSYTRNWGQASLE-CLRMGSSLVSIESAAESSFL 1282
Score = 214 bits (545), Expect = 4e-55
Identities = 253/1072 (23%), Positives = 403/1072 (37%), Gaps = 164/1072 (15%)
Query: 242 CYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSK-TVEVWMGLNQLDEH 300
CY+ + +A ++C+ +GG L SI E +FI + + E+W+GLN +
Sbjct: 373 CYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQ 432
Query: 301 AGWQWSDGTPLNYLNW-SPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLN 359
++WSDGTP+ + W E + E ++ C W R CE L YICK
Sbjct: 433 MYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKG-KDGYWADRGCEWPLGYICKMKSR 491
Query: 360 HIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSL 419
EIVE + C GW ++ CY + T+ EA ++C +N+ L I
Sbjct: 492 SQGPEIVEVEKG------CRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDR 545
Query: 420 AEVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCV 479
E FL + +G W GLS + +F+W+ + V FT+W++ P R CV
Sbjct: 546 YEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNS----DMPGRKPGCV 601
Query: 480 SAEQ--SEGHWKVKNCEERLFYICKKAGHVLSDA-------ESGCQEGW--ERHGGFCYK 528
+ + G W V C+E+ ++CK ++ E C E W C+K
Sbjct: 602 AMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFK 661
Query: 529 IDTV----------LRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDSY--- 575
+ R F +A G L +I N+ EQ I LI++ SY
Sbjct: 662 LYAKGKHEKKTWFESRDFCRALGG-----DLASINNKEEQQTIWRLITA----SGSYHKL 712
Query: 576 FWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGG---CVAMRGRHPLGRWEVK 632
FW+ L + + +TW PV Y +W +P C ++G P W
Sbjct: 713 FWLGLTYGSPSEGFTWSD----GSPVSYENWAYGEPNNYQNVEYCGELKG-DPTMSWNDI 767
Query: 633 HCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLM---K 689
+C H +C+ K E P ++ P + ++ + K
Sbjct: 768 NCEHLNNW-ICQIQKGQTPKPE--------PTPAPQDNPPVTEDGWVIYKDYQYYFSKEK 818
Query: 690 RTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGF----NKRNPLN 745
T A AFC+ L S E+ F+ + ++ + ++IG +K+
Sbjct: 819 ETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRN---DAQSAYFIGLLISLDKKF--- 872
Query: 746 AGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKANKTLL-PLHCGSKREWICKIPRD--- 801
+W + VS F + NC +N ++CG +IC+
Sbjct: 873 --AWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSIN 930
Query: 802 ---VKPKIPFWYQYDVP------WLFYQDAEYLFHTFASE----WLNFEFVCSWLHSDLL 848
V P +P VP W FY + + F E W C +L+
Sbjct: 931 ATTVMPTMP-----SVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLV 985
Query: 849 TIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTG----RE 904
+I + EQ F+ +K S + A W GL + + F W DG V Y NW G R
Sbjct: 986 SIQNEKEQAFLTYHMKD-STFSA--WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRR 1042
Query: 905 RTVNNQSQRC----GFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK 960
+++ + C G S+ G W + C IC+ + + T + G
Sbjct: 1043 SSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKY 1102
Query: 961 GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS 1020
G +Y + W A+ +C + +I AF + +
Sbjct: 1103 G--KSSYSLMRQKF--------QWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNER 1152
Query: 1021 VWIGLQN---DDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFH 1077
VWI L + D+ TW + V Y+NW+ + K C L +
Sbjct: 1153 VWIALNSNLTDNQYTWTDKWRVRYTNWA------------ADEPKLKSACVYLDLD---- 1196
Query: 1078 FTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKI--------I 1129
G W C + Y F+C++ + + ++ +P + T I I
Sbjct: 1197 --GYWKTAHCNESFY-FLCKRSDE-----IPATEPPQLPGRCPESDHTAWIPFHGHCYYI 1248
Query: 1130 NANMT--WYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYA--HWIGLFTTDNGLNF 1185
++ T W A CL + LVSI SFL+ + L WIGLF G +
Sbjct: 1249 ESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEG-TW 1307
Query: 1186 DWSDGTKSSFTFWK-DEESSLLGDCV-FADSNGRWHSTACESFLQGAICHVP 1235
W + + SF W + S DCV S+G W + C S+ +G IC P
Sbjct: 1308 LWINNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCSSY-KGYICKRP 1358
Score = 184 bits (468), Expect = 4e-46
Identities = 197/793 (24%), Positives = 312/793 (39%), Gaps = 97/793 (12%)
Query: 220 PDPTSA-EVGCDTIWEKDLNSHICYQFNLLSS---LSWSEAHSSCQMQGGTLLSITDETE 275
P PT+ E C W + +C++ +W E+ C+ GG L SI ++ E
Sbjct: 636 PKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEE 695
Query: 276 ENFIREHMSSKTVE---VWMGLNQLDEHAGWQWSDGTPLNYLNWS-PEVNFEPFVEDHCG 331
+ I +++ W+GL G+ WSDG+P++Y NW+ E N VE +CG
Sbjct: 696 QQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVE-YCG 754
Query: 332 TFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYK 391
+W +CE +IC+ A + E GW Y Y
Sbjct: 755 ELKGDPTMSWNDINCEHLNNWICQIQKGQTPKP-EPTPAPQDNPPVTEDGWVIYKDYQYY 813
Query: 392 LQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETW-IGLSSNKIPVSF 450
KE++T A C+ + L+ I S +E +FL + +A + IGL + + F
Sbjct: 814 FSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLIS-LDKKF 872
Query: 451 EWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLS- 509
W + S V + +W T EP+ F N + CV+ + G W NC +IC++ ++
Sbjct: 873 AWMDGSKVDYVSWATGEPN-FANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINA 931
Query: 510 --------DAESGCQEGWERHGGFCYKI----DTVLRSFDQASSGYY-CPPALVTITNRF 556
SGC+EGW + C+KI + +++ +A LV+I N
Sbjct: 932 TTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEK 991
Query: 557 EQAFITSLISSVVKMKDSYF--WIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR-- 612
EQAF+T MKDS F W L D N + W V YT+W P
Sbjct: 992 EQAFLT------YHMKDSTFSAWTGLNDVNSEHTFLWTD----GRGVHYTNWGKGYPGGR 1041
Query: 613 ------YSGGCVAMRG--RHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPC 664
CV + G + G+W C K +C Q +++ P
Sbjct: 1042 RSSLSYEDADCVVIIGGASNEAGKWMDDTCDS-KRGYIC------QTRSDPSLTNPPATI 1094
Query: 665 YLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHS 724
D + G +S + K W EAE +C+ + +AS + + N
Sbjct: 1095 QTDGFVKYGKSSY------SLMRQKFQWHEAETYCKLHNSLIASIL----DPYSNAFAWL 1144
Query: 725 KFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARN----CAVYKAN 780
+ + ER WI N L + W+D+ V T + D C +
Sbjct: 1145 QMETSNER-VWIALNSN--LTDNQYTWTDKWRV-----RYTNWAADEPKLKSACVYLDLD 1196
Query: 781 KTLLPLHCGSKREWICK----IPRDVKPKIPFWYQYD--VPWL-FYQDAEYLFHTFASEW 833
HC ++CK IP P++P W+ F+ Y+ ++ W
Sbjct: 1197 GYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNW 1256
Query: 834 LNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTP 893
C + S L++I SA E F+ +++ L K ++WIGL + W + +P
Sbjct: 1257 GQASLECLRMGSSLVSIESAAESSFLSYRVEPL-KSKTNFWIGLFRN-VEGTWLWINNSP 1314
Query: 894 VIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKV-------WLIE 946
V + NW+TG N C + + +G W + CS ICKR K+ L+
Sbjct: 1315 VSFVNWNTGDPSGERND---CVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLT 1371
Query: 947 KKKDTPKQHGTCP 959
K DT K + P
Sbjct: 1372 TKADTRKMDPSKP 1384
Score = 179 bits (455), Expect = 1e-44
Identities = 201/879 (22%), Positives = 345/879 (39%), Gaps = 99/879 (11%)
Query: 220 PDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFI 279
P+ E GC W+K + CY S +++EA+ +C + L +I D E+ F+
Sbjct: 495 PEIVEVEKGCRKGWKK--HHFYCYMIGHTLS-TFAEANQTCNNENAYLTTIEDRYEQAFL 551
Query: 280 REHMSSKTVEV-WMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP 338
+ + + W GL+ + +QW+ + + +W+ ++ P + C + +
Sbjct: 552 TSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDM---PGRKPGCVAMRTGIA 608
Query: 339 SA-WRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRN--CYKL--- 392
W C+ ++CK + + H + C W +R C+KL
Sbjct: 609 GGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPE---PKCPEDWGASSRTSLCFKLYAK 665
Query: 393 -QKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET--WIGLSSNKIPVS 449
+ E+KTW E+ C+A L I + E + + L+ + W+GL+
Sbjct: 666 GKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEG 725
Query: 450 FEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK------- 502
F WS+ S V + NW EP+ + N W NCE +IC+
Sbjct: 726 FTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTP 785
Query: 503 --KAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA---LVTITNRFE 557
+ D ++GW + + Y + D A + +C LV+I + E
Sbjct: 786 KPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARA--FCKRNFGDLVSIQSESE 843
Query: 558 QAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSG-- 615
+ F+ ++ S ++I L D ++ W G K V Y W T +P ++
Sbjct: 844 KKFLWKYVNR--NDAQSAYFIGLLISLDK-KFAWMD-GSK---VDYVSWATGEPNFANED 896
Query: 616 -GCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHP--CYLDWESEP 672
CV M G W +C + A +C++ + P P C W
Sbjct: 897 ENCVTMYSNS--GFWNDINCGYPNAF-ICQRHNSSINATTVMPTMPSVPSGCKEGWNFYS 953
Query: 673 GLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVN-ELLHSKFNWTEE 731
CFK+F + ++ W+EA C FG +L S + +E+ F+ + S F+
Sbjct: 954 N--KCFKIFGFMEE-ERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFS---- 1006
Query: 732 RQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFG--------EDARNCAVY------ 777
W G N N + ++ W+D V + Y G EDA +C V
Sbjct: 1007 --AWTGLNDVN--SEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDA-DCVVIIGGASN 1061
Query: 778 KANKTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFE 837
+A K + C SKR +IC+ D P ++ Y + Y +W E
Sbjct: 1062 EAGKWMDDT-CDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAE 1120
Query: 838 FVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQ 897
C +S + +I + F +++ ++ WI L ++++ W D V Y
Sbjct: 1121 TYCKLHNSLIASILDPYSNAFAWLQMETSNE---RVWIALNSNLTDNQYTWTDKWRVRYT 1177
Query: 898 NWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGT 957
NW + C ++ + G W + C+ S +CKR + P+ G
Sbjct: 1178 NWAADEPKL----KSACVYLD-LDGYWKTAHCNESFYFLCKRSDEI---PATEPPQLPGR 1229
Query: 958 CPKG----WLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMN 1013
CP+ W+ F+ C + + S +NW A C G +LV+IES E +F++
Sbjct: 1230 CPESDHTAWIPFHGHCYYI----ESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYR 1285
Query: 1014 L--FGQTTSVWIGLQNDDYETWL--NGKPVVYSNWSPFD 1048
+ T+ WIGL + TWL N PV + NW+ D
Sbjct: 1286 VEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGD 1324
Score = 116 bits (290), Expect = 2e-25
Identities = 124/521 (23%), Positives = 199/521 (38%), Gaps = 59/521 (11%)
Query: 830 ASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWR 889
A W C +++LL+I HEQ ++ +L+ + WIGL N ++W
Sbjct: 237 ALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLT---SGLWIGLNSLSFNSGWQWS 293
Query: 890 DGTPVIYQNWDTGRERTVNNQSQRCGFIS-SITGLWGSEECSVSMPSICKRKKVWL---- 944
D +P Y NW G +S C ++ W + EC + ICK+ L
Sbjct: 294 DRSPFRYLNWLPGSPSAEPGKS--CVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFV 351
Query: 945 IEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESE 1004
I + D P CP W + C I +D K A C +EGG L +I +
Sbjct: 352 IPSESDVPTH---CPSQWWPYAGHCY--KIHRDEK--KIQRDALTTCRKEGGDLTSIHTI 404
Query: 1005 VEQAFITMNL-FGQTTSVWIGLQN---DDYETWLNGKPVVYSNWSPFDIINIPSHNTTEV 1060
E FI L + +WIGL + Y W +G PV ++ W + PSH
Sbjct: 405 EELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKW----LRGEPSHENNRQ 460
Query: 1061 QKHIPLCALLSSNPNFHFTGKWYFEDCGKEG-YGFVCEKMQDTSGHGVNTSDMYPMPNTL 1119
+ C ++ Y+ D G E G++C+ + G + +
Sbjct: 461 ED----CVVMKGKDG-------YWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWK 509
Query: 1120 EYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLN-RLGYAHWIGLFT 1178
++ Y I + T+ A +TC A L +I D+Y Q+FLT + R W GL
Sbjct: 510 KHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSD 569
Query: 1179 TDNGLNFDWSDGTKSSFTFWKDEESSLLGDCVFADSN---GRWHSTACESFLQ------- 1228
F W+ + FT W + CV + G W C+ +
Sbjct: 570 IQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWA 629
Query: 1229 GAICHVP-----PETRQSEHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKE 1283
+ H P PE + E S TS+ + + + T +S +FC+
Sbjct: 630 EGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFES------RDFCRAL 683
Query: 1284 GSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFDGNSK 1324
G +L +I ++ E + + A GS ++ WL + S+
Sbjct: 684 GGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSE 724
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 77.4 bits (189), Expect = 8e-14
Identities = 31/66 (46%), Positives = 41/66 (62%)
Query: 163 HKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDP 222
H+ L T+ GN G PC FPF++ + CT EGR D WC TT Y+RD+K+GFCP+
Sbjct: 226 HEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPET 285
Query: 223 TSAEVG 228
+ VG
Sbjct: 286 AMSTVG 291
Score = 75.1 bits (183), Expect = 4e-13
Identities = 28/56 (50%), Positives = 37/56 (66%)
Query: 166 LHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPD 221
+ T+ GN+ G PC+FPF + + CT GR D +WCATT+ Y+ D KWGFCPD
Sbjct: 287 MSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPD 342
Score = 63.9 bits (154), Expect = 1e-09
Identities = 25/50 (50%), Positives = 33/50 (66%)
Query: 171 GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCP 220
GN G C FPF +N + ++ CT GR D LWC+TT +E+D K+GFCP
Sbjct: 176 GNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCP 225
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 77.4 bits (189), Expect = 8e-14
Identities = 31/66 (46%), Positives = 41/66 (62%)
Query: 163 HKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDP 222
H+ L T+ GN G PC FPF++ + CT EGR D WC TT Y+RD+K+GFCP+
Sbjct: 276 HEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPET 335
Query: 223 TSAEVG 228
+ VG
Sbjct: 336 AMSTVG 341
Score = 75.1 bits (183), Expect = 4e-13
Identities = 28/56 (50%), Positives = 37/56 (66%)
Query: 166 LHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPD 221
+ T+ GN+ G PC+FPF + + CT GR D +WCATT+ Y+ D KWGFCPD
Sbjct: 337 MSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPD 392
Score = 63.9 bits (154), Expect = 1e-09
Identities = 25/50 (50%), Positives = 33/50 (66%)
Query: 171 GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCP 220
GN G C FPF +N + ++ CT GR D LWC+TT +E+D K+GFCP
Sbjct: 226 GNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCP 275
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 75.9 bits (185), Expect = 2e-13
Identities = 43/128 (33%), Positives = 60/128 (46%), Gaps = 7/128 (5%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASE- 436
CE GWN Y +CY+ + +TW +A R C+ S L I + E EF+ + NA +
Sbjct: 2206 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFV-----NNNAQDY 2260
Query: 437 TWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLC-VSAEQSEGHWKVKNCEE 495
WIGL+ I F WS+ + F NW +P F + C V +G W C
Sbjct: 2261 QWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2320
Query: 496 RLFYICKK 503
L + CKK
Sbjct: 2321 HLPFTCKK 2328
Score = 58.5 bits (140), Expect = 4e-08
Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 9/130 (6%)
Query: 229 CDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTV 288
C+ W K H CY+ + +W +A C+ Q L SI E+ F+ +
Sbjct: 2206 CEEGWNK-YQGH-CYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2261
Query: 289 EVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEV--NFEPFVEDHCGTFSSFMPSAWRSRDC 346
W+GLN ++WSDG P+ + NW P NF ED C W C
Sbjct: 2262 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGED-CVVMIWHEKGEWNDVPC 2318
Query: 347 ESTLPYICKK 356
LP+ CKK
Sbjct: 2319 NYHLPFTCKK 2328
Score = 57.4 bits (137), Expect = 9e-08
Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 7/128 (5%)
Query: 816 WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWI 875
W YQ Y W++ E C S L +I + EQEF+++ + WI
Sbjct: 2210 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ------WI 2263
Query: 876 GLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECSVSMP 934
GL + +FRW DG P+ ++NW + + C I G W C+ +P
Sbjct: 2264 GLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLP 2323
Query: 935 SICKRKKV 942
CK+ V
Sbjct: 2324 FTCKKGTV 2331
Score = 53.1 bits (126), Expect = 2e-06
Identities = 63/248 (25%), Positives = 92/248 (37%), Gaps = 59/248 (23%)
Query: 436 ETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
ET + IP S EW +S P RS AE+ G K E
Sbjct: 2138 ETATSPTDASIPASPEWKRESE---------STAAAPARS----CAEEPCGAGTCKETEG 2184
Query: 496 RLFYICKKA--GHVLSDAESGCQEGWERHGGFCYK--------IDTVLRSFDQASSGYYC 545
+ +C G + + C+EGW ++ G CY+ +D R +Q S
Sbjct: 2185 HVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH---- 2240
Query: 546 PPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTH 605
L +I EQ F+ + Y WI L D+ G++ W P+Q+ +
Sbjct: 2241 ---LSSIVTPEEQEFVNN-------NAQDYQWIGLNDRTIEGDFRW----SDGHPMQFEN 2286
Query: 606 WNTHQPR--YSGG--CVAMRGRHPLGRWEVKHCRHF------KAMSLCKQP--VEN---- 649
W +QP ++ G CV M H G W C + K C +P VE+
Sbjct: 2287 WRPNQPDNFFAAGEDCVVMIW-HEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTF 2345
Query: 650 -QEKAEYE 656
Q+K YE
Sbjct: 2346 GQKKDRYE 2353
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 17/94 (18%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W G C++ F + TW +AE C E +HL+S EE+ FVN
Sbjct: 2206 CEEGWNKYQG--HCYRHFPD-----RETWVDAERRCREQQSHLSSIVTPEEQEFVN---- 2254
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPV 757
N ++ Q WIG N R G + WSD P+
Sbjct: 2255 ---NNAQDYQ-WIGLNDRT--IEGDFRWSDGHPM 2282
Score = 40.4 bits (93), Expect = 0.011
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 11/92 (11%)
Query: 958 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1017
C +GW + C + + W A+ C E+ L +I + EQ F+ N
Sbjct: 2206 CEEGWNKYQGHCY-----RHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNN---A 2257
Query: 1018 TTSVWIGLQNDDYE---TWLNGKPVVYSNWSP 1046
WIGL + E W +G P+ + NW P
Sbjct: 2258 QDYQWIGLNDRTIEGDFRWSDGHPMQFENWRP 2289
Score = 40.4 bits (93), Expect = 0.011
Identities = 35/129 (27%), Positives = 47/129 (36%), Gaps = 15/129 (11%)
Query: 1120 EYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTT 1179
+Y Y+ TW A + C ++ L SI Q F+ N WIGL
Sbjct: 2212 KYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN---NNAQDYQWIGLNDR 2268
Query: 1180 DNGLNFDWSDGTKSSFTFWK----DEESSLLGDCVFA--DSNGRWHSTACESFL-----Q 1228
+F WSDG F W+ D + DCV G W+ C L +
Sbjct: 2269 TIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKK 2328
Query: 1229 GAI-CHVPP 1236
G + C PP
Sbjct: 2329 GTVACGEPP 2337
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 75.9 bits (185), Expect = 2e-13
Identities = 43/128 (33%), Positives = 60/128 (46%), Gaps = 7/128 (5%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASE- 436
CE GWN Y +CY+ + +TW +A R C+ S L I + E EF+ + NA +
Sbjct: 2168 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFV-----NNNAQDY 2222
Query: 437 TWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLC-VSAEQSEGHWKVKNCEE 495
WIGL+ I F WS+ + F NW +P F + C V +G W C
Sbjct: 2223 QWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2282
Query: 496 RLFYICKK 503
L + CKK
Sbjct: 2283 HLPFTCKK 2290
Score = 58.5 bits (140), Expect = 4e-08
Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 9/130 (6%)
Query: 229 CDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTV 288
C+ W K H CY+ + +W +A C+ Q L SI E+ F+ +
Sbjct: 2168 CEEGWNK-YQGH-CYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2223
Query: 289 EVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEV--NFEPFVEDHCGTFSSFMPSAWRSRDC 346
W+GLN ++WSDG P+ + NW P NF ED C W C
Sbjct: 2224 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGED-CVVMIWHEKGEWNDVPC 2280
Query: 347 ESTLPYICKK 356
LP+ CKK
Sbjct: 2281 NYHLPFTCKK 2290
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 7/125 (5%)
Query: 816 WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWI 875
W YQ Y W++ E C S L +I + EQEF+++ + WI
Sbjct: 2172 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ------WI 2225
Query: 876 GLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECSVSMP 934
GL + +FRW DG P+ ++NW + + C I G W C+ +P
Sbjct: 2226 GLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLP 2285
Query: 935 SICKR 939
CK+
Sbjct: 2286 FTCKK 2290
Score = 53.1 bits (126), Expect = 2e-06
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 32/161 (19%)
Query: 515 CQEGWERHGGFCYK--------IDTVLRSFDQASSGYYCPPALVTITNRFEQAFITSLIS 566
C+EGW ++ G CY+ +D R +Q S L +I EQ F+ +
Sbjct: 2168 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH-------LSSIVTPEEQEFVNN--- 2217
Query: 567 SVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR--YSGG--CVAMRG 622
Y WI L D+ G++ W P+Q+ +W +QP ++ G CV M
Sbjct: 2218 ----NAQDYQWIGLNDRTIEGDFRW----SDGHPMQFENWRPNQPDNFFAAGEDCVVMIW 2269
Query: 623 RHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHP 663
H G W C + + CK+ K ++R HP
Sbjct: 2270 -HEKGEWNDVPCNYHLPFT-CKKGTATTYKRRLQKRSSRHP 2308
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 17/94 (18%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W G C++ F + TW +AE C E +HL+S EE+ FVN
Sbjct: 2168 CEEGWNKYQG--HCYRHFPD-----RETWVDAERRCREQQSHLSSIVTPEEQEFVN---- 2216
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPV 757
N ++ Q WIG N R G + WSD P+
Sbjct: 2217 ---NNAQDYQ-WIGLNDRT--IEGDFRWSDGHPM 2244
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 11/103 (10%)
Query: 947 KKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVE 1006
+ + T C +GW + C + + W A+ C E+ L +I + E
Sbjct: 2157 ESESTAADQEVCEEGWNKYQGHCY-----RHFPDRETWVDAERRCREQQSHLSSIVTPEE 2211
Query: 1007 QAFITMNLFGQTTSVWIGLQNDDYE---TWLNGKPVVYSNWSP 1046
Q F+ N WIGL + E W +G P+ + NW P
Sbjct: 2212 QEFVNNN---AQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRP 2251
Score = 40.0 bits (92), Expect = 0.015
Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 9/114 (7%)
Query: 1120 EYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTT 1179
+Y Y+ TW A + C ++ L SI Q F+ N WIGL
Sbjct: 2174 KYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN---NNAQDYQWIGLNDR 2230
Query: 1180 DNGLNFDWSDGTKSSFTFWK----DEESSLLGDCVFA--DSNGRWHSTACESFL 1227
+F WSDG F W+ D + DCV G W+ C L
Sbjct: 2231 TIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHL 2284
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
Length = 657
Score = 75.1 bits (183), Expect = 4e-13
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 168 TIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPT 223
T GN++G PC+ PF YN + + CT EGR+D LWC+TTS YE+D+K+ FC D T
Sbjct: 350 TYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHT 405
Score = 72.4 bits (176), Expect = 3e-12
Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 106 CDSTLVSLRW--RCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLH 163
C T V+ + N + P Y+ + + T R+ H W S S +Y
Sbjct: 342 CQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT-EGRQDGHLWCSTTSNYEQDQKYSF 400
Query: 164 KDLHTIK-----GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGF 218
HT+ GN++G C FPF YN+ + +CT EGR D++ WC TT Y+ D+K+GF
Sbjct: 401 CTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGF 460
Query: 219 CPDPTSAEVGCDT 231
CP E+ C T
Sbjct: 461 CPMAAHEEI-CTT 472
>gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]
Length = 794
Score = 74.7 bits (182), Expect = 5e-13
Identities = 31/54 (57%), Positives = 37/54 (68%)
Query: 166 LHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFC 219
L I+G HG PC FPF + + + ECT +GRED LWCATT Y+ DEKWGFC
Sbjct: 115 LTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFC 168
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 74.3 bits (181), Expect = 7e-13
Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C+ GW+ + +CY+ + W +A + C+ + L + S E F + G EN T
Sbjct: 1088 CDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSF-INSFGHEN---T 1143
Query: 438 WIGLSSNKIPVSFEWSNDSSVIFTNWHTLEP-HIFPNRSQLCVSAEQSEGHWKVKNCEER 496
WIGL+ + F+W++++ + F NW +P + F V G W C
Sbjct: 1144 WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYN 1203
Query: 497 LFYICKK 503
L Y+CKK
Sbjct: 1204 LPYVCKK 1210
Score = 68.9 bits (167), Expect = 3e-11
Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 12/141 (8%)
Query: 218 FCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEEN 277
FC T GCD W K H CY++ +W +A C+ + G L S+ E +
Sbjct: 1080 FCEKDTE---GCDRGWHK-FQGH-CYRY-FAHRRAWEDAEKDCRRRSGHLTSVHSPEEHS 1133
Query: 278 FIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNW--SPEVNFEPFVEDHCGTFSS 335
FI T W+GLN +QW+D T L + NW + NF ED C +
Sbjct: 1134 FINSFGHENT---WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGED-CVVMVA 1189
Query: 336 FMPSAWRSRDCESTLPYICKK 356
W C LPY+CKK
Sbjct: 1190 HESGRWNDVPCNYNLPYVCKK 1210
Score = 55.8 bits (133), Expect = 3e-07
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 813 DVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYG-A 871
D W +Q Y + W + E C L ++HS E FI+S +G
Sbjct: 1089 DRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINS-------FGHE 1141
Query: 872 SWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECS 930
+ WIGL + +F+W D T + ++NW + + C ++ +G W C+
Sbjct: 1142 NTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCN 1201
Query: 931 VSMPSICKRKKV 942
++P +CK+ V
Sbjct: 1202 YNLPYVCKKGTV 1213
Score = 44.3 bits (103), Expect = 8e-04
Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 11/144 (7%)
Query: 1087 CGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHK 1146
C E GFVC + G ++ Y+ W A K C
Sbjct: 1061 CIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRS 1120
Query: 1147 AQLVSITDQYHQSFLTVVLNRLGYAH-WIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSL 1205
L S+ SF+ N G+ + WIGL +F W+D T F W++ +
Sbjct: 1121 GHLTSVHSPEEHSFI----NSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDN 1176
Query: 1206 L----GDCV--FADSNGRWHSTAC 1223
DCV A +GRW+ C
Sbjct: 1177 FFAGGEDCVVMVAHESGRWNDVPC 1200
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 28/142 (19%)
Query: 514 GCQEGWERHGGFCYKIDTVLRSFDQAS------SGYYCPPALVTITNRFEQAFITSLISS 567
GC GW + G CY+ R+++ A SG+ L ++ + E +FI S
Sbjct: 1087 GCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGH-----LTSVHSPEEHSFINS---- 1137
Query: 568 VVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR--YSGG--CVAMRGR 623
WI L D+ ++ W +Q+ +W +QP ++GG CV M
Sbjct: 1138 ---FGHENTWIGLNDRIVERDFQW----TDNTGLQFENWRENQPDNFFAGGEDCVVMVA- 1189
Query: 624 HPLGRWEVKHCRHFKAMSLCKQ 645
H GRW C ++ +CK+
Sbjct: 1190 HESGRWNDVPC-NYNLPYVCKK 1210
Score = 40.0 bits (92), Expect = 0.015
Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 26/141 (18%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W G C++ F +R W +AE C HL S EE +F+N H
Sbjct: 1088 CDRGWHKFQG--HCYRYFAH-----RRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGH 1140
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVV-----SSFLDNTYFGEDARNCAVYK 778
WIG N R + ++W+D T + + DN + G +C V
Sbjct: 1141 --------ENTWIGLNDR--IVERDFQWTDNTGLQFENWRENQPDNFFAG--GEDCVVMV 1188
Query: 779 ANKT--LLPLHCGSKREWICK 797
A+++ + C ++CK
Sbjct: 1189 AHESGRWNDVPCNYNLPYVCK 1209
Score = 37.4 bits (85), Expect = 0.096
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Query: 958 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1017
C +GW F C + + W A+ C G L ++ S E +FI N FG
Sbjct: 1088 CDRGWHKFQGHCYRYFAHR-----RAWEDAEKDCRRRSGHLTSVHSPEEHSFI--NSFGH 1140
Query: 1018 TTSVWIGLQNDDYE---TWLNGKPVVYSNW 1044
+ WIGL + E W + + + NW
Sbjct: 1141 -ENTWIGLNDRIVERDFQWTDNTGLQFENW 1169
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 73.2 bits (178), Expect = 2e-12
Identities = 27/63 (42%), Positives = 40/63 (63%)
Query: 167 HTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAE 226
HT+ G PC FPFQY+ Q +H+CT +GR WCATT +++D++WG+C +P +
Sbjct: 36 HTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVK 95
Query: 227 VGC 229
C
Sbjct: 96 DHC 98
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 70.1 bits (170), Expect = 1e-11
Identities = 29/62 (46%), Positives = 38/62 (61%)
Query: 166 LHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSA 225
L+T GN G PC FPF + Q + CT +GR D WCATT+ Y+RD+ +GFCP +
Sbjct: 276 LYTQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADS 335
Query: 226 EV 227
V
Sbjct: 336 TV 337
Score = 70.1 bits (170), Expect = 1e-11
Identities = 29/57 (50%), Positives = 38/57 (66%)
Query: 165 DLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPD 221
D + GN+ G C+FPF + + + CT EGR D LWCATTS ++ D+KWGFCPD
Sbjct: 334 DSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPD 390
Score = 61.6 bits (148), Expect = 5e-09
Identities = 23/50 (46%), Positives = 33/50 (66%)
Query: 171 GNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCP 220
GN G C FPF + + + CT +GR D L WC+TT+ Y+ D+++GFCP
Sbjct: 223 GNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCP 272
>gi|187607300 versican isoform 2 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 1e-11
Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 5/127 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C+ GW+ + CYK +TW A R C+ + L I S E + V +G +
Sbjct: 428 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILS-HEEQMFVNRVGHD---YQ 483
Query: 438 WIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSE-GHWKVKNCEER 496
WIGL+ F W++ S++ + NW +P F + + CV E G W C
Sbjct: 484 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYH 543
Query: 497 LFYICKK 503
L Y CKK
Sbjct: 544 LTYTCKK 550
Score = 56.6 bits (135), Expect = 2e-07
Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 229 CDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTV 288
CD W K CY++ +W A C++QG L SI E+ F+
Sbjct: 428 CDYGWHKFQGQ--CYKY-FAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ- 483
Query: 289 EVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPF-VEDHCGTFSSFMPSAWRSRDCE 347
W+GLN ++W+DG+ L Y NW P F + C W C
Sbjct: 484 --WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 541
Query: 348 STLPYICKK 356
L Y CKK
Sbjct: 542 YHLTYTCKK 550
Score = 52.8 bits (125), Expect = 2e-06
Identities = 44/157 (28%), Positives = 67/157 (42%), Gaps = 28/157 (17%)
Query: 1093 GFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSI 1152
G +CE+ +T +G + ++ + YK TW AA + C + A L SI
Sbjct: 418 GALCEQDTETCDYGWH-----------KFQGQCYKYFAHRRTWDAAERECRLQGAHLTSI 466
Query: 1153 TDQYHQSFLTVVLNRLGYAH-WIGLFTTDNGLNFDWSDGTKSSFTFWK----DEESSLLG 1207
Q F +NR+G+ + WIGL +F W+DG+ + W+ D S
Sbjct: 467 LSHEEQMF----VNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGE 522
Query: 1208 DCVFA--DSNGRWHSTACESFL-----QGAI-CHVPP 1236
DCV NG+W+ C L +G + C PP
Sbjct: 523 DCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPP 559
Score = 51.2 bits (121), Expect = 6e-06
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 9/132 (6%)
Query: 813 DVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGAS 872
D W +Q Y + W E C + L +I S EQ F++ + G
Sbjct: 429 DYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN-------RVGHD 481
Query: 873 W-WIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECS 930
+ WIGL ++ +FRW DG+ + Y+NW + + + + C I G W C+
Sbjct: 482 YQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 541
Query: 931 VSMPSICKRKKV 942
+ CK+ V
Sbjct: 542 YHLTYTCKKGTV 553
Score = 45.4 bits (106), Expect = 4e-04
Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 515 CQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLISSVVKMKD 573
C GW + G CYK R++D A A L +I + EQ F+ ++
Sbjct: 428 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN-------RVGH 480
Query: 574 SYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR--YSGG--CVAMRGRHPLGRW 629
Y WI L D+ ++ W +QY +W +QP +S G CV + H G+W
Sbjct: 481 DYQWIGLNDKMFEHDFRW----TDGSTLQYENWRPNQPDSFFSAGEDCVVIIW-HENGQW 535
Query: 630 EVKHCRHF------KAMSLCKQP--VEN 649
C + K C QP VEN
Sbjct: 536 NDVPCNYHLTYTCKKGTVACGQPPVVEN 563
Score = 45.1 bits (105), Expect = 5e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
Query: 957 TCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFG 1016
TC GW F +C K + + W A+ C +G L +I S EQ F+ N G
Sbjct: 427 TCDYGWHKFQGQCY-----KYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFV--NRVG 479
Query: 1017 QTTSVWIGLQNDDYE---TWLNGKPVVYSNWSP 1046
WIGL + +E W +G + Y NW P
Sbjct: 480 HDYQ-WIGLNDKMFEHDFRWTDGSTLQYENWRP 511
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 17/90 (18%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W G C+K F +RTW AE C GAHL S EE+ FVN + H
Sbjct: 428 CDYGWHKFQG--QCYKYFAH-----RRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGH 480
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSD 753
WIG N + + + W+D
Sbjct: 481 D--------YQWIGLNDK--MFEHDFRWTD 500
>gi|21361116 versican isoform 1 [Homo sapiens]
Length = 3396
Score = 70.1 bits (170), Expect = 1e-11
Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 5/127 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C+ GW+ + CYK +TW A R C+ + L I S E + V +G +
Sbjct: 3169 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILS-HEEQMFVNRVGHD---YQ 3224
Query: 438 WIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSE-GHWKVKNCEER 496
WIGL+ F W++ S++ + NW +P F + + CV E G W C
Sbjct: 3225 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYH 3284
Query: 497 LFYICKK 503
L Y CKK
Sbjct: 3285 LTYTCKK 3291
Score = 56.6 bits (135), Expect = 2e-07
Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 229 CDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTV 288
CD W K CY++ +W A C++QG L SI E+ F+
Sbjct: 3169 CDYGWHKFQGQ--CYKY-FAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ- 3224
Query: 289 EVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPF-VEDHCGTFSSFMPSAWRSRDCE 347
W+GLN ++W+DG+ L Y NW P F + C W C
Sbjct: 3225 --WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 3282
Query: 348 STLPYICKK 356
L Y CKK
Sbjct: 3283 YHLTYTCKK 3291
Score = 52.8 bits (125), Expect = 2e-06
Identities = 44/157 (28%), Positives = 67/157 (42%), Gaps = 28/157 (17%)
Query: 1093 GFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSI 1152
G +CE+ +T +G + ++ + YK TW AA + C + A L SI
Sbjct: 3159 GALCEQDTETCDYGWH-----------KFQGQCYKYFAHRRTWDAAERECRLQGAHLTSI 3207
Query: 1153 TDQYHQSFLTVVLNRLGYAH-WIGLFTTDNGLNFDWSDGTKSSFTFWK----DEESSLLG 1207
Q F +NR+G+ + WIGL +F W+DG+ + W+ D S
Sbjct: 3208 LSHEEQMF----VNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGE 3263
Query: 1208 DCVFA--DSNGRWHSTACESFL-----QGAI-CHVPP 1236
DCV NG+W+ C L +G + C PP
Sbjct: 3264 DCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPP 3300
Score = 51.2 bits (121), Expect = 6e-06
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 9/132 (6%)
Query: 813 DVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGAS 872
D W +Q Y + W E C + L +I S EQ F++ + G
Sbjct: 3170 DYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN-------RVGHD 3222
Query: 873 W-WIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECS 930
+ WIGL ++ +FRW DG+ + Y+NW + + + + C I G W C+
Sbjct: 3223 YQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 3282
Query: 931 VSMPSICKRKKV 942
+ CK+ V
Sbjct: 3283 YHLTYTCKKGTV 3294
Score = 45.4 bits (106), Expect = 4e-04
Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 515 CQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLISSVVKMKD 573
C GW + G CYK R++D A A L +I + EQ F+ ++
Sbjct: 3169 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN-------RVGH 3221
Query: 574 SYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR--YSGG--CVAMRGRHPLGRW 629
Y WI L D+ ++ W +QY +W +QP +S G CV + H G+W
Sbjct: 3222 DYQWIGLNDKMFEHDFRW----TDGSTLQYENWRPNQPDSFFSAGEDCVVIIW-HENGQW 3276
Query: 630 EVKHCRHF------KAMSLCKQP--VEN 649
C + K C QP VEN
Sbjct: 3277 NDVPCNYHLTYTCKKGTVACGQPPVVEN 3304
Score = 45.1 bits (105), Expect = 5e-04
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
Query: 957 TCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFG 1016
TC GW F +C K + + W A+ C +G L +I S EQ F+ N G
Sbjct: 3168 TCDYGWHKFQGQCY-----KYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFV--NRVG 3220
Query: 1017 QTTSVWIGLQNDDYE---TWLNGKPVVYSNWSP 1046
WIGL + +E W +G + Y NW P
Sbjct: 3221 HDYQ-WIGLNDKMFEHDFRWTDGSTLQYENWRP 3252
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 17/90 (18%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W G C+K F +RTW AE C GAHL S EE+ FVN + H
Sbjct: 3169 CDYGWHKFQG--QCYKYFAH-----RRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGH 3221
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSD 753
WIG N + + + W+D
Sbjct: 3222 D--------YQWIGLNDK--MFEHDFRWTD 3241
>gi|10835248 regenerating islet-derived 1 beta precursor [Homo
sapiens]
Length = 166
Score = 68.6 bits (166), Expect = 4e-11
Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSA-LIDITSLAEVEFLVTLLGDENA-- 434
C G N Y CY ++ +TW +A CQ NS L+ + + AE F+ +L+ + +
Sbjct: 36 CPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDD 95
Query: 435 SETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEG--HWKVKN 492
S WIGL K + WS+ S V + +W T P + C S G WK ++
Sbjct: 96 SNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPS--SANAGYCASLTSCSGFKKWKDES 153
Query: 493 CEERLFYICK 502
CE++ ++CK
Sbjct: 154 CEKKFSFVCK 163
Score = 65.5 bits (158), Expect = 3e-10
Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 819 YQDAEYLFHTFASEWLNFEFVCSWLHS-DLLTIHSAHEQEFIHSKIKALSKYGASWWIGL 877
Y+ Y F+ W++ + C ++S +L+++ + E F+ S IK S ++ WIGL
Sbjct: 43 YRSYCYYFNEDPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGL 102
Query: 878 QEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGL--WGSEECSVSMPS 935
+ + N + W G+ V Y++WDTG + N + C ++S +G W E C
Sbjct: 103 HDPKKNRRWHWSSGSLVSYKSWDTGSPSSAN--AGYCASLTSCSGFKKWKDESCEKKFSF 160
Query: 936 ICKRK 940
+CK K
Sbjct: 161 VCKFK 165
Score = 54.3 bits (129), Expect = 8e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
Query: 242 CYQFNLLSSLSWSEAHSSCQ-MQGGTLLSITDETEENFIREHMSSKTVE---VWMGLNQL 297
CY FN +W +A CQ M G L+S+ + E F+ + + + VW+GL+
Sbjct: 47 CYYFNE-DPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDP 105
Query: 298 DEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP-SAWRSRDCESTLPYICK 355
++ W WS G+ ++Y +W + +C + +S W+ CE ++CK
Sbjct: 106 KKNRRWHWSSGSLVSYKSWDTG-SPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCK 163
Score = 32.3 bits (72), Expect = 3.1
Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 9/100 (9%)
Query: 1134 TWYAAIKTCL-MHKAQLVSITDQYHQSFLTVVLNRLGYAH---WIGLFTTDNGLNFDWSD 1189
TW A C M+ LVS+ Q +F+ ++ WIGL + WS
Sbjct: 56 TWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSS 115
Query: 1190 GTKSSFTFWK--DEESSLLGDCVFADSNG---RWHSTACE 1224
G+ S+ W S+ G C S +W +CE
Sbjct: 116 GSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCE 155
>gi|45580692 C-type lectin domain family 4, member C isoform 2 [Homo
sapiens]
Length = 182
Score = 68.6 bits (166), Expect = 4e-11
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 16/143 (11%)
Query: 809 WYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSK 868
W PW +Q + Y T W + CS + +DL+ I++ EQ+FI +K S
Sbjct: 49 WSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSS 108
Query: 869 YGASWWIGLQEERANDEFRWRDGTPVIYQN----WDTGRERTVNNQSQRCGFI---SSIT 921
Y ++GL + ++W D TP Y W +G NN +RC I SS
Sbjct: 109 Y----FLGLSDPGGRRHWQWVDQTP--YNENVTFWHSGEP---NNLDERCAIINFRSSEE 159
Query: 922 GLWGSEECSVSMPSICKRKKVWL 944
W C V SICK KK+++
Sbjct: 160 WGWNDIHCHVPQKSICKMKKIYI 182
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 22/147 (14%)
Query: 214 EKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDE 273
E W CP P W +S CY F SW+++ +C + G L+ I
Sbjct: 47 EDWSCCPTP----------WTSFQSS--CY-FISTGMQSWTKSQKNCSVMGADLVVINTR 93
Query: 274 TEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPL--NYLNW-SPEVNFEPFVEDHC 330
E++FI +++ + ++GL+ WQW D TP N W S E N +++ C
Sbjct: 94 EEQDFIIQNL-KRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPN---NLDERC 149
Query: 331 G--TFSSFMPSAWRSRDCESTLPYICK 355
F S W C ICK
Sbjct: 150 AIINFRSSEEWGWNDIHCHVPQKSICK 176
Score = 44.7 bits (104), Expect = 6e-04
Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 4/127 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C W + +CY + ++W ++ ++C + L+ I + E +F++ L + S
Sbjct: 52 CPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNL--KRNSSY 109
Query: 438 WIGLSSNKIPVSFEWSNDS--SVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
++GLS ++W + + + T WH+ EP+ R + E W +C
Sbjct: 110 FLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHV 169
Query: 496 RLFYICK 502
ICK
Sbjct: 170 PQKSICK 176
Score = 40.8 bits (94), Expect = 0.009
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 13/136 (9%)
Query: 513 SGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLISSVVKM 571
S C W CY I T ++S+ ++ A LV I R EQ FI + K
Sbjct: 50 SCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNL----KR 105
Query: 572 KDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSG---GCVAMRGRHPLGR 628
SYF + L D G W+ V Q P T W++ +P + R G
Sbjct: 106 NSSYF-LGLSDPG--GRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWG- 161
Query: 629 WEVKHCRHFKAMSLCK 644
W HC H S+CK
Sbjct: 162 WNDIHC-HVPQKSICK 176
Score = 35.0 bits (79), Expect = 0.48
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 1253 PWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEEL 1303
PW F+S+CY ST + S+ + + C G++L+ I E F+++ L
Sbjct: 55 PWTSFQSSCYFISTGM--QSWTKSQKNCSVMGADLVVINTREEQDFIIQNL 103
Score = 34.3 bits (77), Expect = 0.81
Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 28/163 (17%)
Query: 654 EYEERWPFHPCYLDWESEPGLASC---FKVFHSEKVLMK---RTWREAEAFCEEFGAHLA 707
EY++ P C ++ + + C + F S + ++W +++ C GA L
Sbjct: 29 EYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLV 88
Query: 708 SFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYF 767
EE++F+ + N +++G + +P W+W D+TP + +N F
Sbjct: 89 VINTREEQDFIIQ------NLKRNSSYFLGLS--DPGGRRHWQWVDQTP----YNENVTF 136
Query: 768 GEDA------RNCAVYKANKT----LLPLHCGSKREWICKIPR 800
CA+ + +HC ++ ICK+ +
Sbjct: 137 WHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKK 179
Score = 34.3 bits (77), Expect = 0.81
Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 14/130 (10%)
Query: 1114 PMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHW 1173
P P T + + Y I +W + K C + A LV I + Q F+ L R +++
Sbjct: 53 PTPWT-SFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKR-NSSYF 110
Query: 1174 IGLFTTDNGLNFDWSDGT--KSSFTFWKDEESSLLGD-CVFAD--SNGRWHSTACESFLQ 1228
+GL ++ W D T + TFW E + L + C + S+ W
Sbjct: 111 LGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIH---- 166
Query: 1229 GAICHVPPET 1238
CHVP ++
Sbjct: 167 ---CHVPQKS 173
>gi|18466806 C-type lectin domain family 4, member C isoform 1 [Homo
sapiens]
Length = 213
Score = 68.6 bits (166), Expect = 4e-11
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 16/143 (11%)
Query: 809 WYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSK 868
W PW +Q + Y T W + CS + +DL+ I++ EQ+FI +K S
Sbjct: 80 WSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSS 139
Query: 869 YGASWWIGLQEERANDEFRWRDGTPVIYQN----WDTGRERTVNNQSQRCGFI---SSIT 921
Y ++GL + ++W D TP Y W +G NN +RC I SS
Sbjct: 140 Y----FLGLSDPGGRRHWQWVDQTP--YNENVTFWHSGEP---NNLDERCAIINFRSSEE 190
Query: 922 GLWGSEECSVSMPSICKRKKVWL 944
W C V SICK KK+++
Sbjct: 191 WGWNDIHCHVPQKSICKMKKIYI 213
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 22/147 (14%)
Query: 214 EKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDE 273
E W CP P W +S CY F SW+++ +C + G L+ I
Sbjct: 78 EDWSCCPTP----------WTSFQSS--CY-FISTGMQSWTKSQKNCSVMGADLVVINTR 124
Query: 274 TEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPL--NYLNW-SPEVNFEPFVEDHC 330
E++FI +++ + ++GL+ WQW D TP N W S E N +++ C
Sbjct: 125 EEQDFIIQNL-KRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPN---NLDERC 180
Query: 331 G--TFSSFMPSAWRSRDCESTLPYICK 355
F S W C ICK
Sbjct: 181 AIINFRSSEEWGWNDIHCHVPQKSICK 207
Score = 44.7 bits (104), Expect = 6e-04
Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 4/127 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C W + +CY + ++W ++ ++C + L+ I + E +F++ L + S
Sbjct: 83 CPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNL--KRNSSY 140
Query: 438 WIGLSSNKIPVSFEWSNDS--SVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
++GLS ++W + + + T WH+ EP+ R + E W +C
Sbjct: 141 FLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHV 200
Query: 496 RLFYICK 502
ICK
Sbjct: 201 PQKSICK 207
Score = 40.8 bits (94), Expect = 0.009
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 13/136 (9%)
Query: 513 SGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLISSVVKM 571
S C W CY I T ++S+ ++ A LV I R EQ FI + K
Sbjct: 81 SCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNL----KR 136
Query: 572 KDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSG---GCVAMRGRHPLGR 628
SYF + L D G W+ V Q P T W++ +P + R G
Sbjct: 137 NSSYF-LGLSDPG--GRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWG- 192
Query: 629 WEVKHCRHFKAMSLCK 644
W HC H S+CK
Sbjct: 193 WNDIHC-HVPQKSICK 207
Score = 35.0 bits (79), Expect = 0.48
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 1253 PWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEEL 1303
PW F+S+CY ST + S+ + + C G++L+ I E F+++ L
Sbjct: 86 PWTSFQSSCYFISTGM--QSWTKSQKNCSVMGADLVVINTREEQDFIIQNL 134
Score = 34.3 bits (77), Expect = 0.81
Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 28/163 (17%)
Query: 654 EYEERWPFHPCYLDWESEPGLASC---FKVFHSEKVLMK---RTWREAEAFCEEFGAHLA 707
EY++ P C ++ + + C + F S + ++W +++ C GA L
Sbjct: 60 EYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLV 119
Query: 708 SFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYF 767
EE++F+ + N +++G + +P W+W D+TP + +N F
Sbjct: 120 VINTREEQDFIIQ------NLKRNSSYFLGLS--DPGGRRHWQWVDQTP----YNENVTF 167
Query: 768 GEDA------RNCAVYKANKT----LLPLHCGSKREWICKIPR 800
CA+ + +HC ++ ICK+ +
Sbjct: 168 WHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKK 210
Score = 34.3 bits (77), Expect = 0.81
Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 14/130 (10%)
Query: 1114 PMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHW 1173
P P T + + Y I +W + K C + A LV I + Q F+ L R +++
Sbjct: 84 PTPWT-SFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKR-NSSYF 141
Query: 1174 IGLFTTDNGLNFDWSDGT--KSSFTFWKDEESSLLGD-CVFAD--SNGRWHSTACESFLQ 1228
+GL ++ W D T + TFW E + L + C + S+ W
Sbjct: 142 LGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIH---- 197
Query: 1229 GAICHVPPET 1238
CHVP ++
Sbjct: 198 ---CHVPQKS 204
>gi|20149533 Fc fragment of IgE, low affinity II, receptor for (CD23A)
[Homo sapiens]
Length = 321
Score = 68.2 bits (165), Expect = 5e-11
Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 25/146 (17%)
Query: 957 TCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFG 1016
TCP+ W+ F KC K W HA++ C + G LV+I S EQ F+T +
Sbjct: 162 TCPEKWINFQRKCYYFG-----KGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKH--A 214
Query: 1017 QTTSVWIGLQNDDYE---TWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSN 1073
T WIGL+N D + W++G V YSNW+P + P+ + C ++
Sbjct: 215 SHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGE----PTSRSQGED-----CVMMRG- 264
Query: 1074 PNFHFTGKWYFEDCGKEGYGFVCEKM 1099
+G+W C ++ +VC+++
Sbjct: 265 -----SGRWNDAFCDRKLGAWVCDRL 285
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 816 WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWI 875
W+ +Q Y F +W++ + C + L++IHS EQ+F+ K S G+ WI
Sbjct: 167 WINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFL---TKHASHTGS--WI 221
Query: 876 GLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPS 935
GL+ EF W DG+ V Y NW G E T +Q + C + +G W C + +
Sbjct: 222 GLRNLDLKGEFIWVDGSHVDYSNWAPG-EPTSRSQGEDCVMMRG-SGRWNDAFCDRKLGA 279
Query: 936 -ICKR 939
+C R
Sbjct: 280 WVCDR 284
Score = 57.8 bits (138), Expect = 7e-08
Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 10/143 (6%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C W + R CY K K W A +C L+ I S E +FL ++AS T
Sbjct: 163 CPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLT-----KHASHT 217
Query: 438 --WIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
WIGL + + F W + S V ++NW EP ++ + CV S G W C+
Sbjct: 218 GSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEP-TSRSQGEDCVMMRGS-GRWNDAFCDR 275
Query: 496 RL-FYICKKAGHVLSDAESGCQE 517
+L ++C + A G E
Sbjct: 276 KLGAWVCDRLATCTPPASEGSAE 298
Score = 54.7 bits (130), Expect = 6e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
Query: 229 CDTIWEKDLN-SHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKT 287
C+T EK +N CY F + W A +C G L+SI E++F+ +H S
Sbjct: 160 CNTCPEKWINFQRKCYYFGK-GTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASH-- 216
Query: 288 VEVWMGLNQLDEHAGWQWSDGTPLNYLNWSP 318
W+GL LD + W DG+ ++Y NW+P
Sbjct: 217 TGSWIGLRNLDLKGEFIWVDGSHVDYSNWAP 247
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 9/138 (6%)
Query: 1098 KMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYH 1157
++Q +SG NT + + + Y W A C + QLVSI
Sbjct: 151 ELQVSSGFVCNTCP----EKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEE 206
Query: 1158 QSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLG---DCVFADS 1214
Q FLT + G WIGL D F W DG+ ++ W E + DCV
Sbjct: 207 QDFLTKHASHTG--SWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRG 264
Query: 1215 NGRWHSTACESFLQGAIC 1232
+GRW+ C+ L +C
Sbjct: 265 SGRWNDAFCDRKLGAWVC 282
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 67.8 bits (164), Expect = 7e-11
Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 5/126 (3%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C PGW+ + CYK ++W EA C+ + L I++ E +F + +
Sbjct: 688 CNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDF----INNRYREYQ 743
Query: 438 WIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLC-VSAEQSEGHWKVKNCEER 496
WIGL+ I F WS+ +++ NW+ +P + + C V +G W C
Sbjct: 744 WIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYH 803
Query: 497 LFYICK 502
L Y CK
Sbjct: 804 LSYTCK 809
Score = 63.9 bits (154), Expect = 1e-09
Identities = 40/128 (31%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 229 CDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTV 288
C+ W D CY+ + + SW EA + C+M G L SI+ E++FI
Sbjct: 688 CNPGW--DAFQGACYK-HFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQ- 743
Query: 289 EVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVE-DHCGTFSSFMPSAWRSRDCE 347
W+GLN + WSDG PL Y NW+P F+ ++C W C
Sbjct: 744 --WIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCN 801
Query: 348 STLPYICK 355
L Y CK
Sbjct: 802 YHLSYTCK 809
Score = 61.6 bits (148), Expect = 5e-09
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 7/124 (5%)
Query: 816 WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWI 875
W +Q A Y + W E C + L +I + EQ+FI+++ Y WI
Sbjct: 692 WDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNR------YREYQWI 745
Query: 876 GLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRC-GFISSITGLWGSEECSVSMP 934
GL + +F W DG P++Y+NW+ G+ + + C + G W C+ +
Sbjct: 746 GLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLS 805
Query: 935 SICK 938
CK
Sbjct: 806 YTCK 809
Score = 54.7 bits (130), Expect = 6e-07
Identities = 35/95 (36%), Positives = 50/95 (52%), Gaps = 17/95 (17%)
Query: 664 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 723
C W++ G +C+K F + +R+W EAE C +GAHLAS + EE++F+N
Sbjct: 688 CNPGWDAFQG--ACYKHFST-----RRSWEEAETQCRMYGAHLASISTPEEQDFIN---- 736
Query: 724 SKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVV 758
N E Q WIG N R G + WSD P++
Sbjct: 737 ---NRYREYQ-WIGLNDRT--IEGDFLWSDGVPLL 765
Score = 49.7 bits (117), Expect = 2e-05
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 17/127 (13%)
Query: 515 CQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPA-LVTITNRFEQAFITSLISSVVKMKD 573
C GW+ G CYK + RS+++A + A L +I+ EQ FI +
Sbjct: 688 CNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYR------- 740
Query: 574 SYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPR---YSG-GCVAMRGRHPLGRW 629
Y WI L D+ G++ W P+ Y +WN QP SG CV M H G+W
Sbjct: 741 EYQWIGLNDRTIEGDFLW----SDGVPLLYENWNPGQPDSYFLSGENCVVMVW-HDQGQW 795
Query: 630 EVKHCRH 636
C +
Sbjct: 796 SDVPCNY 802
Score = 45.4 bits (106), Expect = 4e-04
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 958 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1017
C GW F C K S+ ++W A+ C G L +I + EQ FI N + +
Sbjct: 688 CNPGWDAFQGACY-----KHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFIN-NRYRE 741
Query: 1018 TTSVWIGLQNDDYE---TWLNGKPVVYSNWSP 1046
WIGL + E W +G P++Y NW+P
Sbjct: 742 YQ--WIGLNDRTIEGDFLWSDGVPLLYENWNP 771
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/163 (26%), Positives = 59/163 (36%), Gaps = 15/163 (9%)
Query: 1087 CGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHK 1146
C +E G C + G + + P + YK + +W A C M+
Sbjct: 661 CLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYG 720
Query: 1147 AQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWK--DEESS 1204
A L SI+ Q F+ NR WIGL +F WSDG + W +S
Sbjct: 721 AHLASISTPEEQDFIN---NRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSY 777
Query: 1205 LLG--DCVFA--DSNGRWHSTACESFL-----QGAI-CHVPPE 1237
L +CV G+W C L G + C PPE
Sbjct: 778 FLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPE 820
>gi|29725633 regenerating islet-derived 1 alpha precursor [Homo
sapiens]
Length = 166
Score = 65.1 bits (157), Expect = 4e-10
Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSA-LIDITSLAEVEFLVTLLGDENASE 436
C G N Y CY ++ +TW +A CQ NS L+ + + AE F+ +L+ + +
Sbjct: 36 CPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDD 95
Query: 437 --TWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEG--HWKVKN 492
WIGL K + WS+ S V + +W P CVS S G WK
Sbjct: 96 FNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSV--NPGYCVSLTSSTGFQKWKDVP 153
Query: 493 CEERLFYICK 502
CE++ ++CK
Sbjct: 154 CEDKFSFVCK 163
Score = 55.1 bits (131), Expect = 4e-07
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
Query: 819 YQDAEYLFHTFASEWLNFEFVCSWLHS-DLLTIHSAHEQEFIHSKIKALSKYGASWWIGL 877
Y+ Y F+ W++ + C ++S +L+++ + E F+ S IK + WIGL
Sbjct: 43 YRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGL 102
Query: 878 QEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGL--WGSEECSVSMPS 935
+ + N + W G+ V Y++W G +VN C ++S TG W C
Sbjct: 103 HDPKKNRRWHWSSGSLVSYKSWGIGAPSSVN--PGYCVSLTSSTGFQKWKDVPCEDKFSF 160
Query: 936 ICKRK 940
+CK K
Sbjct: 161 VCKFK 165
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 242 CYQFNLLSSLSWSEAHSSCQ-MQGGTLLSITDETEENFIREHMSSKTVE---VWMGLNQL 297
CY FN +W +A CQ M G L+S+ + E F+ + + VW+GL+
Sbjct: 47 CYYFNE-DRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDP 105
Query: 298 DEHAGWQWSDGTPLNYLNWS----PEVNFEPFVEDHCGTFSSFMP-SAWRSRDCESTLPY 352
++ W WS G+ ++Y +W VN +C + +S W+ CE +
Sbjct: 106 KKNRRWHWSSGSLVSYKSWGIGAPSSVN-----PGYCVSLTSSTGFQKWKDVPCEDKFSF 160
Query: 353 ICK 355
+CK
Sbjct: 161 VCK 163
Score = 36.6 bits (83), Expect = 0.16
Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 1118 TLEYGNRTYKIINANMTWYAAIKTCL-MHKAQLVSITDQYHQSFLTVVLNRLG---YAHW 1173
T Y + Y TW A C M+ LVS+ Q +F+ ++ G + W
Sbjct: 40 TNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVW 99
Query: 1174 IGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLL--GDCVFADSN---GRWHSTACE 1224
IGL + WS G+ S+ W S + G CV S+ +W CE
Sbjct: 100 IGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCE 155
>gi|223029517 CD209 molecule isoform 8 [Homo sapiens]
Length = 243
Score = 63.9 bits (154), Expect = 1e-09
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
Query: 233 WEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWM 292
WE CY F S +W ++ ++C+ G L+ I E+NF++ S WM
Sbjct: 97 WEWTFFQGNCY-FMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 155
Query: 293 GLNQLDEHAGWQWSDGTPL-----NYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCE 347
GL+ L++ WQW DG+PL Y N N E+ C FS + W C
Sbjct: 156 GLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVG---EEDCAEFSG---NGWNDDKCN 209
Query: 348 STLPYICKK 356
+ICKK
Sbjct: 210 LAKFWICKK 218
Score = 58.2 bits (139), Expect = 5e-08
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 19/140 (13%)
Query: 662 HPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNEL 721
HPC +W G +C+ + +S+ R W ++ C+E GA L EE+NF+ +L
Sbjct: 93 HPCPWEWTFFQG--NCYFMSNSQ-----RNWHDSITACKEVGAQLVVIKSAEEQNFL-QL 144
Query: 722 LHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGE----DARNCAVY 777
S+ N R W+G + N G+W+W D +P++ SF GE +CA +
Sbjct: 145 QSSRSN----RFTWMGLSDLN--QEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEF 198
Query: 778 KANKTLLPLHCGSKREWICK 797
N C + WICK
Sbjct: 199 SGN-GWNDDKCNLAKFWICK 217
Score = 57.8 bits (138), Expect = 7e-08
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 378 CEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET 437
C W + NCY + ++ WH+++ +C+ + L+ I S E FL L + T
Sbjct: 95 CPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFL-QLQSSRSNRFT 153
Query: 438 WIGLSSNKIPVSFEWSNDSSVIFT---NWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCE 494
W+GLS +++W + S ++ + W+ EP+ AE S W C
Sbjct: 154 WMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEED----CAEFSGNGWNDDKCN 209
Query: 495 ERLFYICKKA 504
F+ICKK+
Sbjct: 210 LAKFWICKKS 219
Score = 52.0 bits (123), Expect = 4e-06
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 10/127 (7%)
Query: 816 WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWI 875
W F+Q Y W + C + + L+ I SA EQ F+ + +++ W+
Sbjct: 99 WTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFT---WM 155
Query: 876 GLQEERANDEFRWRDGTPVI---YQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVS 932
GL + ++W DG+P++ Q W+ G V + C S W ++C+++
Sbjct: 156 GLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEED--CAEFSG--NGWNDDKCNLA 211
Query: 933 MPSICKR 939
ICK+
Sbjct: 212 KFWICKK 218
Score = 47.4 bits (111), Expect = 9e-05
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 958 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1017
CP W +F C ++ +S +NW + C E G LV I+S EQ F+ +
Sbjct: 95 CPWEWTFFQGNCYFMS-----NSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRS 149
Query: 1018 TTSVWIGLQNDDYE---TWLNGKPVVYS 1042
W+GL + + E W++G P++ S
Sbjct: 150 NRFTWMGLSDLNQEGTWQWVDGSPLLPS 177
Score = 44.7 bits (104), Expect = 6e-04
Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 7/115 (6%)
Query: 1114 PMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHW 1173
P T GN Y + N+ W+ +I C AQLV I Q+FL + +R W
Sbjct: 96 PWEWTFFQGN-CYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTW 154
Query: 1174 IGLFTTDNGLNFDWSDGT---KSSFTFWKDEESSLLG--DCVFADSNGRWHSTAC 1223
+GL + + W DG+ S +W E + +G DC NG W+ C
Sbjct: 155 MGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNG-WNDDKC 208
Score = 31.2 bits (69), Expect = 6.9
Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 2/54 (3%)
Query: 1246 LCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFL 1299
LC W F+ NCY S ++ + CK+ G+ L+ IK E FL
Sbjct: 91 LCHPCPWEWTFFQGNCYFMSN--SQRNWHDSITACKEVGAQLVVIKSAEEQNFL 142
Score = 31.2 bits (69), Expect = 6.9
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 515 CQEGWERHGGFCYKIDTVLRSF-DQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKD 573
C W G CY + R++ D ++ LV I + EQ F+ L SS +
Sbjct: 95 CPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFL-QLQSS---RSN 150
Query: 574 SYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSG 615
+ W+ L D N G + W G P +WN +P G
Sbjct: 151 RFTWMGLSDLNQEGTWQWVD-GSPLLPSFKQYWNRGEPNNVG 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,008,559
Number of Sequences: 37866
Number of extensions: 2823655
Number of successful extensions: 6649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 5068
Number of HSP's gapped (non-prelim): 879
length of query: 1324
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1210
effective length of database: 13,930,794
effective search space: 16856260740
effective search space used: 16856260740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.