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Search of human proteins with 55743073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform
b [Homo sapiens]
(1258 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform ... 2449 0.0
gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform ... 1360 0.0
gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo ... 814 0.0
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 93 1e-18
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 93 1e-18
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 93 1e-18
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 93 1e-18
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 87 1e-16
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 87 1e-16
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 87 1e-16
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 87 1e-16
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 87 1e-16
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 87 1e-16
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 87 1e-16
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 85 4e-16
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 85 4e-16
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 85 4e-16
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 85 4e-16
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 85 4e-16
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 84 8e-16
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 80 1e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 78 5e-14
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 78 5e-14
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 77 8e-14
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 76 2e-13
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 76 2e-13
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 75 3e-13
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 75 4e-13
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 75 4e-13
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 74 7e-13
>gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform b
[Homo sapiens]
Length = 1258
Score = 2449 bits (6347), Expect = 0.0
Identities = 1258/1258 (100%), Positives = 1258/1258 (100%)
Query: 1 MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS
Sbjct: 1 MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
Query: 61 TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG
Sbjct: 61 TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
Query: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN
Sbjct: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
Query: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN
Sbjct: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
Query: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK
Sbjct: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
Query: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST
Sbjct: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
Query: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM
Sbjct: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
Query: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ
Sbjct: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
Query: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL
Sbjct: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
Query: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA
Sbjct: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
Query: 601 TSKALVKFDPEIIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPM 660
TSKALVKFDPEIIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPM
Sbjct: 601 TSKALVKFDPEIIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPM 660
Query: 661 ELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGS 720
ELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGS
Sbjct: 661 ELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGS 720
Query: 721 VLIKATHVGNDTTLAQIVKLVEEAQMSKNPNKHISQTEVIIRFAFQTSITVLCIACPCSL 780
VLIKATHVGNDTTLAQIVKLVEEAQMSKNPNKHISQTEVIIRFAFQTSITVLCIACPCSL
Sbjct: 721 VLIKATHVGNDTTLAQIVKLVEEAQMSKNPNKHISQTEVIIRFAFQTSITVLCIACPCSL 780
Query: 781 GLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
GLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD
Sbjct: 781 GLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
Query: 841 VATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVS 900
VATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVS
Sbjct: 841 VATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVS 900
Query: 901 NVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSD 960
NVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSD
Sbjct: 901 NVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSD 960
Query: 961 AMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTA 1020
AMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTA
Sbjct: 961 AMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTA 1020
Query: 1021 RAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTG 1080
RAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTG
Sbjct: 1021 RAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTG 1080
Query: 1081 TDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIG 1140
TDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIG
Sbjct: 1081 TDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIG 1140
Query: 1141 IVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMD 1200
IVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMD
Sbjct: 1141 IVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMD 1200
Query: 1201 DRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1258
DRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI
Sbjct: 1201 DRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1258
>gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform a
[Homo sapiens]
Length = 1465
Score = 1360 bits (3521), Expect = 0.0
Identities = 811/1360 (59%), Positives = 916/1360 (67%), Gaps = 190/1360 (13%)
Query: 55 SQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCH 114
+Q A +R+ GMTCQSCV SIE ++ L+G++ +KVSL A + Y P ++ + +
Sbjct: 140 AQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRD 199
Query: 115 QIGDMGFEASIAEGKA-------------ASWPSRSLPAQE----------------AVV 145
+ DMGFEA+I A ++ P R L + +
Sbjct: 200 HVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTL 259
Query: 146 KLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMG 205
+LR++GM C+SCV +IE + +L GV ++VSL N+ A + Y P P
Sbjct: 260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSP----------- 308
Query: 206 FEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGH------QGSHVVTL 259
A++ + L G + S + ++S + G QG+ TL
Sbjct: 309 --VALQRAIEALPPGNFKVSLPDGAEG----SGTDHRSSSSHSPGSPPRNQVQGTCSTTL 362
Query: 260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEAL- 318
+ I GM C SCV +IE I QL GVQ I VSL TA V Y+PS SP L+ AIE +
Sbjct: 363 -IAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMG 421
Query: 319 -------------PPGNFKV--SLPDGAEGSGTDHRSSSSHSPGSP----PRNQVQGTCS 359
P GN S+ +G+ T + + H+ P P + S
Sbjct: 422 FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQS 481
Query: 360 TTLIA-------IAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEE 412
T +A I GMTCASCV +IE + + GV + V+L G A + Y+P VI P E
Sbjct: 482 TRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLE 541
Query: 413 LRAAIEDMGFEASVVSESCSTNPLGN--------------HSAGNSMVQTTDGTPTSVQE 458
+ I+D+GFEA+V+ + ++ GN H+ + + +T T SV
Sbjct: 542 IAQFIQDLGFEAAVMEDYAGSD--GNIELTITGMTCASCVHNIESKLTRTNGITYASV-- 597
Query: 459 VAPHTGRLPANHAPDILAKSPQSTRAVAPQKCF-----------------LQIKGMTCAS 501
A T + P+I+ P+ + + F ++IK S
Sbjct: 598 -ALATSKALVKFDPEIIG--PRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWK-KS 653
Query: 502 CVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQ--------FIQDLG--- 550
+ ++ + A ++ +L+ + D +I L I F+Q LG
Sbjct: 654 FLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWY 713
Query: 551 FEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDP 610
F + N+++ I T + V+++ I +VA ++ V F
Sbjct: 714 FYVQAYKSLRHRSANMDVLIVLATSIAYVYSLV--------ILVVAVAEKAERSPVTFFD 765
Query: 611 E-------IIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV 663
I R + + +SKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV
Sbjct: 766 TPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELV 825
Query: 664 QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI 723
QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI
Sbjct: 826 QRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLI 885
Query: 724 KATHVGNDTTLAQIVKLVEEAQMSK----------------------------------- 748
KATHVGNDTTLAQIVKLVEEAQMSK
Sbjct: 886 KATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFI 945
Query: 749 ----------NPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN 798
NPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN
Sbjct: 946 DFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQN 1005
Query: 799 GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA 858
GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA
Sbjct: 1006 GILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEA 1065
Query: 859 SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS 918
SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS
Sbjct: 1066 SSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPAS 1125
Query: 919 HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 978
HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID
Sbjct: 1126 HLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 1185
Query: 979 GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1038
GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP
Sbjct: 1186 GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1245
Query: 1039 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1098
SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL
Sbjct: 1246 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1305
Query: 1099 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1158
DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS
Sbjct: 1306 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1365
Query: 1159 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1218
VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV
Sbjct: 1366 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1425
Query: 1219 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1258
SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI
Sbjct: 1426 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI 1465
Score = 1221 bits (3160), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 1 MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS
Sbjct: 1 MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATS 60
Query: 61 TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG
Sbjct: 61 TVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMG 120
Query: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN
Sbjct: 121 FEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSN 180
Query: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN
Sbjct: 181 QEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSAN 240
Query: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK
Sbjct: 241 QNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVK 300
Query: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST
Sbjct: 301 YDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCST 360
Query: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM
Sbjct: 361 TLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDM 420
Query: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ
Sbjct: 421 GFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQ 480
Query: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL
Sbjct: 481 STRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPL 540
Query: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA
Sbjct: 541 EIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
Query: 601 TSKALVKFDPEIIGPRDIIKIIE 623
TSKALVKFDPEIIGPRDIIKIIE
Sbjct: 601 TSKALVKFDPEIIGPRDIIKIIE 623
Score = 194 bits (494), Expect = 3e-49
Identities = 142/451 (31%), Positives = 214/451 (47%), Gaps = 78/451 (17%)
Query: 25 PTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLK 84
P R A + + +G++G S V T +RI GM C+SCV +IE+ I L
Sbjct: 232 PKRPLSSANQNFNNSETLGHQG--------SHVVTLQLRIDGMHCKSCVLNIEENIGQLL 283
Query: 85 GIISMKVSLEQGSATVKYVPSV---VCLQQVCHQIGDMGFEASIAEGKAASW-------- 133
G+ S++VSLE +A VKY PS V LQ+ + F+ S+ +G S
Sbjct: 284 GVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS 343
Query: 134 ------PSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITY 187
P + + + + GMTC SCV SIEG + +L+GV ++ VSL+ A + Y
Sbjct: 344 HSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLY 403
Query: 188 QPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS-LG---------------PIDIERLQSTN 231
P +I PE+LR + DMGFEA++ S+ + LG P ++ +
Sbjct: 404 NPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHT 463
Query: 232 PKRPLSSANQNFNNSETLGHQGSHVVTLQ---LRIDGMHCKSCVLNIEENIGQLLGVQSI 288
+ P + A S Q + V Q L+I GM C SCV NIE N+ + GV S+
Sbjct: 464 GRLPANHAPDILAKSP----QSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
Query: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGS 348
V+L A++KYDP P+ + + I+ L F+ ++ + GS
Sbjct: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDL---GFEAAVMEDYAGS-------------- 562
Query: 349 PPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVI 408
G T I GMTCASCVH+IE +++ G+ SV+LA A V ++P +I
Sbjct: 563 ------DGNIELT---ITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEII 613
Query: 409 SPEELRAAIEDMGFEASVVSESCSTNPLGNH 439
P ++ IE++GF AS+ NP +H
Sbjct: 614 GPRDIIKIIEEIGFHASLAQR----NPNAHH 640
Score = 185 bits (470), Expect = 2e-46
Identities = 137/436 (31%), Positives = 205/436 (47%), Gaps = 74/436 (16%)
Query: 232 PKRPLSSANQNFNNSETLGHQG--------SHVVTLQLRIDGMHCKSCVLNIEENIGQLL 283
P R A + + +G++G S V T +RI GM C+SCV +IE+ I L
Sbjct: 25 PTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLK 84
Query: 284 GVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS 343
G+ S++VSLE +A VKY PS V LQ+ + F+ S+ +G S
Sbjct: 85 GIISMKVSLEQGSATVKYVPSV---VCLQQVCHQIGDMGFEASIAEGKAASW-------- 133
Query: 344 HSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLY 403
P + + + + GMTC SCV SIEG + +L+GV ++ VSL+ A + Y
Sbjct: 134 ------PSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITY 187
Query: 404 NPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHT 463
P +I PE+LR + DMGFEA++ S+ + LG P ++ +
Sbjct: 188 QPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS-LG---------------PIDIERLQSTN 231
Query: 464 GRLPANHAPDILAKSP----QSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
+ P + A S Q + V Q L+I GM C SCV NIE N+ + GV S+
Sbjct: 232 PKRPLSSANQNFNNSETLGHQGSHVVTLQ---LRIDGMHCKSCVLNIEENIGQLLGVQSI 288
Query: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDL---GFEAAVMEDYAGS-------------- 562
V+L A++KYDP P+ + + I+ L F+ ++ + GS
Sbjct: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGS 348
Query: 563 ------DGNIELT---ITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEII 613
G T I GMTCASCVH+IE +++ G+ SV+LA A V ++P +I
Sbjct: 349 PPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVI 408
Query: 614 GPRDIIKIIESKTSEA 629
P ++ IE EA
Sbjct: 409 SPEELRAAIEDMGFEA 424
Score = 98.2 bits (243), Expect = 4e-20
Identities = 51/150 (34%), Positives = 83/150 (55%), Gaps = 9/150 (6%)
Query: 492 LQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGF 551
++I GMTC SCV +IE + G++S+ V+L G A +KY P V+ ++ I D+GF
Sbjct: 62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGF 121
Query: 552 EAAVMEDYAGS---------DGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATS 602
EA++ E A S + ++L + GMTC SCV +IE K+ + G+ V+L+
Sbjct: 122 EASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQ 181
Query: 603 KALVKFDPEIIGPRDIIKIIESKTSEALAK 632
+A++ + P +I P D+ + EA K
Sbjct: 182 EAVITYQPYLIQPEDLRDHVNDMGFEAAIK 211
>gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo
sapiens]
Length = 1500
Score = 814 bits (2102), Expect = 0.0
Identities = 440/697 (63%), Positives = 523/697 (75%), Gaps = 63/697 (9%)
Query: 621 IIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVD 680
I + KTSEALAKL+SLQATEAT+VTL DN+++ EEQV +ELVQRGDI+KVVPGGKFPVD
Sbjct: 800 IAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVD 859
Query: 681 GKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKL 740
G+V+EG++M DESLITGEAMPV KKPGSTVIAGSIN +GS+LI ATHVG DTTL+QIVKL
Sbjct: 860 GRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKL 919
Query: 741 VEEAQMSKNP---------------------------------------------NKHIS 755
VEEAQ SK P N+ IS
Sbjct: 920 VEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
Query: 756 QTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIK 815
+TE IIRFAFQ SITVLCIACPCSLGLATPTAVMVGTGV AQNGILIKGG+PLEMAHK+K
Sbjct: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
Query: 816 TVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEE 875
V+FDKTGTITHG P V +V +L + + K+LA+VGTAE++SEHPLG A+TKYCK+E
Sbjct: 1040 VVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQE 1099
Query: 876 LGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLS-----------APASHLNEAG 924
L TETLG C DFQ VPGCGI CKV+N+EG+L + + AS+ +
Sbjct: 1100 LDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
Query: 925 SLPAEKDAV------PQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 978
S DA Q + VLIGNREW+ RNGL I++DV+D MT+HE KG+TA+LVA+D
Sbjct: 1160 SSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
Query: 979 GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1038
LCG+IAIAD VK EA LA+H L+SMG++VVL+TGDN KTAR+IA+QVGI KVFAEVLP
Sbjct: 1220 DELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLP 1279
Query: 1039 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1098
SHKVAKV++LQ +GK+VAMVGDG+NDSPALA A++G+AIGTGTDVAIEAADVVLIRNDLL
Sbjct: 1280 SHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLL 1339
Query: 1099 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1158
DVVASI LS+ TV+RIRIN V ALIYNLVGIPIAAGVFMPIG+VLQPWMGSAAMAASSVS
Sbjct: 1340 DVVASIDLSRETVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVS 1399
Query: 1159 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1218
VVLSSL LK Y+KP E YE A + + S++SVH+G+DD R+SP+ D++
Sbjct: 1400 VVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNY 1459
Query: 1219 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEE 1255
S+ S++SL SDK S +S + DK SLL+ E+
Sbjct: 1460 SRASINSLLSDKRSLNSVVTSEP-DKHSLLVGDFRED 1495
Score = 436 bits (1120), Expect = e-122
Identities = 257/594 (43%), Positives = 354/594 (59%), Gaps = 31/594 (5%)
Query: 38 AFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGS 97
A D++G++ + P + + + + I+ + KG+ +K+ ++ +
Sbjct: 65 AIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRT 124
Query: 98 ATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLP-AQEAVVKLRVEGMTCQS 156
V +PS+V Q+ + ++ + E K+ + S+ A E V+K++VEGMTC S
Sbjct: 125 VAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHS 184
Query: 157 CVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAP 216
C S+IEGK+ KLQGV R+KVSL NQEA I YQP+LI E+++ + MGF A +K +
Sbjct: 185 CTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKY 244
Query: 217 LSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE 276
L LG ID+ERL++T P+ S+ + S + + T IDGMHCKSCV NIE
Sbjct: 245 LKLGAIDVERLKNT----PVKSSEGSQQRSPSYTNDS----TATFIIDGMHCKSCVSNIE 296
Query: 277 ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGT 336
+ L V SI VSLEN++A VKY+ S +P +L++AIEA+ PG ++VS+ E +
Sbjct: 297 STLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSN 356
Query: 337 DHRSSSSHSPGSPPRNQV-QGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLA 395
S SS S P N V Q T+I I GMTC SCV SIEG+IS+ GV+ I VSLA
Sbjct: 357 ---SPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLA 413
Query: 396 EGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTS 455
TV Y+P + SPE LR AIEDMGF+A++ S + PL P+S
Sbjct: 414 NSNGTVEYDPLLTSPETLRGAIEDMGFDATL---SDTNEPL-----------VVIAQPSS 459
Query: 456 VQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAG 515
+ T + K + KC++Q+ GMTCASCV+NIERNL++E G
Sbjct: 460 EMPLLTSTNEFYTKGMTPVQDKEEGKNSS----KCYIQVTGMTCASCVANIERNLRREEG 515
Query: 516 VLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTC 575
+ S+LVALMAGKAE++Y+P VIQP IA+FI++LGF A V+E+ DG +EL + GMTC
Sbjct: 516 IYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTC 575
Query: 576 ASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIESKTSEA 629
ASCVH IES LT+ GI Y SVALAT+KA +K+DPEIIGPRDII IES EA
Sbjct: 576 ASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEA 629
Score = 227 bits (578), Expect = 6e-59
Identities = 180/581 (30%), Positives = 274/581 (47%), Gaps = 126/581 (21%)
Query: 16 RKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKS 75
++++ +LSL T E KKS A ++ + + +V +++ GMTC SC +
Sbjct: 140 KELVPELSLDTGTLE---KKSGACED-------HSMAQAGEVVLK-MKVEGMTCHSCTST 188
Query: 76 IEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASI---------- 125
IE +I L+G+ +KVSL+ AT+ Y P ++ ++++ QI MGF A +
Sbjct: 189 IEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLG 248
Query: 126 --------------AEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGV 171
+EG PS + ++ ++GM C+SCVS+IE + LQ V
Sbjct: 249 AIDVERLKNTPVKSSEGSQQRSPSYT---NDSTATFIIDGMHCKSCVSNIESTLSALQYV 305
Query: 172 VRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMG---FEAAIKSKVAPLSLGPIDIERLQ 228
+ VSL N+ A++ Y + PE LR + + + +I S+V S P
Sbjct: 306 SSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSS----- 360
Query: 229 STNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSI 288
S+ K PL+ +Q ET+ + IDGM C SCV +IE I + GV+SI
Sbjct: 361 SSLQKIPLNVVSQPLTQ-ETV-----------INIDGMTCNSCVQSIEGVISKKPGVKSI 408
Query: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS----- 343
+VSL N V+YDP TSP L+ AIE + F +L D E + SS
Sbjct: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDM---GFDATLSDTNEPLVVIAQPSSEMPLLT 465
Query: 344 -----HSPG-SPPRNQVQG-TCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAE 396
++ G +P +++ +G S I + GMTCASCV +IE + + EG+ I V+L
Sbjct: 466 STNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMA 525
Query: 397 GTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSV 456
G A V YNP+VI P + I ++GF A+V+ N G+ +++
Sbjct: 526 GKAEVRYNPAVIQPPMIAEFIRELGFGATVIE---------NADEGDGVLE--------- 567
Query: 457 QEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGV 516
L ++GMTCASCV IE +L K G+
Sbjct: 568 -----------------------------------LVVRGMTCASCVHKIESSLTKHRGI 592
Query: 517 LSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME 557
L VAL KA IKYDPE+I P +I I+ LGFEA++++
Sbjct: 593 LYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVK 633
Score = 218 bits (556), Expect = 2e-56
Identities = 179/618 (28%), Positives = 267/618 (43%), Gaps = 118/618 (19%)
Query: 51 LGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQ 110
+ PS V + T+ + GMTC SCV +IE +I + G+ +KVSLE+ +AT+ Y P + +
Sbjct: 1 MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60
Query: 111 QVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQG 170
+ I DMGF+A I LP + L V I+ + K +G
Sbjct: 61 TLQEAIDDMGFDAVIHN-------PDPLPVLTDTLFLTVTASLTLPW-DHIQSTLLKTKG 112
Query: 171 VVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQST 230
V +K+ + +T P ++ IK V LSL +E+
Sbjct: 113 VTDIKIYPQKRTVAVTIIPSIVNANQ-------------IKELVPELSLDTGTLEKKSGA 159
Query: 231 NPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQV 290
++ A + V L+++++GM C SC IE IG+L GVQ I+V
Sbjct: 160 CEDHSMAQAGE---------------VVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKV 204
Query: 291 SLENKTAQVKYDPSCTSPVALQRAIEAL--------PPGNFKVSLPDGAEGSGTDHRSSS 342
SL+N+ A + Y P S +++ IEA+ P K+ D T +SS
Sbjct: 205 SLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSE 264
Query: 343 SHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVL 402
GS R+ ST I GM C SCV +IE +S L+ V I VSL +A V
Sbjct: 265 ----GSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVK 320
Query: 403 YNPSVISPEELRAAIEDMG---FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEV 459
YN S ++PE LR AIE + + S+ SE V++T +P+S
Sbjct: 321 YNASSVTPESLRKAIEAVSPGLYRVSITSE----------------VESTSNSPSS---- 360
Query: 460 APHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
++P N L Q+ + I GMTC SCV +IE + K+ GV S+
Sbjct: 361 -SSLQKIPLNVVSQPLT-----------QETVINIDGMTCNSCVQSIEGVISKKPGVKSI 408
Query: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME---------------------- 557
V+L ++YDP + P + I+D+GF+A + +
Sbjct: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTN 468
Query: 558 -------------DYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKA 604
+ + + +TGMTCASCV NIE L R GI VAL KA
Sbjct: 469 EFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKA 528
Query: 605 LVKFDPEIIGPRDIIKII 622
V+++P +I P I + I
Sbjct: 529 EVRYNPAVIQPPMIAEFI 546
Score = 184 bits (468), Expect = 4e-46
Identities = 130/399 (32%), Positives = 192/399 (48%), Gaps = 54/399 (13%)
Query: 58 ATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVC---LQQVCH 114
+T+T I GM C+SCV +IE +S L+ + S+ VSLE SA VKY S V L++
Sbjct: 277 STATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIE 336
Query: 115 QIGDMGFEASIA---EGKAASWPSRSLP-----------AQEAVVKLRVEGMTCQSCVSS 160
+ + SI E + S S SL QE V+ ++GMTC SCV S
Sbjct: 337 AVSPGLYRVSITSEVESTSNSPSSSSLQKIPLNVVSQPLTQETVIN--IDGMTCNSCVQS 394
Query: 161 IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLG 220
IEG + K GV ++VSL+N + Y P L PE LR + DMGF+A + PL
Sbjct: 395 IEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPL--- 451
Query: 221 PIDIERLQSTNPKRPLSSANQNFNNSETL---GHQGSHVVTLQLRIDGMHCKSCVLNIEE 277
+ Q ++ L+S N+ + T +G + +++ GM C SCV NIE
Sbjct: 452 ---VVIAQPSSEMPLLTSTNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIER 508
Query: 278 NIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTD 337
N+ + G+ SI V+L A+V+Y+P+ P + I L G + D +G
Sbjct: 509 NLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDG---- 564
Query: 338 HRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEG 397
+ + GMTCASCVH IE +++ G+ SV+LA
Sbjct: 565 ----------------------VLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATN 602
Query: 398 TATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPL 436
A + Y+P +I P ++ IE +GFEAS+V + S + L
Sbjct: 603 KAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHL 641
Score = 115 bits (289), Expect = 2e-25
Identities = 108/428 (25%), Positives = 188/428 (43%), Gaps = 81/428 (18%)
Query: 359 STTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIE 418
++ I++ GMTC SCV +IE I ++ GV I VSL E AT++Y+P + +P+ L+ AI+
Sbjct: 8 NSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAID 67
Query: 419 DMGFEA--------SVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGR----- 465
DMGF+A V++++ + + +Q+T V ++ + +
Sbjct: 68 DMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAV 127
Query: 466 ------LPANHAPDILAKSPQSTRAVAPQK---------------CFLQIKGMTCASCVS 504
+ AN +++ + T + + ++++GMTC SC S
Sbjct: 128 TIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHSCTS 187
Query: 505 NIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAV--------- 555
IE + K GV + V+L +A I Y P +I E+ + I+ +GF A V
Sbjct: 188 TIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKL 247
Query: 556 ------------MEDYAGS---------DGNIELTITGMTCASCVHNIESKLTRTNGITY 594
++ GS D I GM C SCV NIES L+ ++
Sbjct: 248 GAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSS 307
Query: 595 ASVALATSKALVKFDPEIIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIR 654
V+L A+VK++ + P + K IE+ S L ++ E+T + +L
Sbjct: 308 IVVSLENRSAIVKYNASSVTPESLRKAIEA-VSPGLYRVSITSEVESTSNSPSSSSL--- 363
Query: 655 EEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGS 714
+++P+ +V + + V +DG + E +I +KKPG I S
Sbjct: 364 -QKIPLNVVSQPLTQETV----INIDGMTCNSCVQSIEGVI-------SKKPGVKSIRVS 411
Query: 715 I-NAHGSV 721
+ N++G+V
Sbjct: 412 LANSNGTV 419
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 93.2 bits (230), Expect = 1e-18
Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1031
G++ I D + AV TL + GV + +ITGD+++TA AIA+++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1032 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1075
VF P HK+ ++ LQ G VAM GDGVND+ AL AD+GV
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1076 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1115
A+G TGTDV EAAD++L+ +D ++++I K I+
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/244 (20%), Positives = 91/244 (37%), Gaps = 48/244 (19%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E ++ ++L +L L E V G+ + + VP GD V + G + P D +
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLR 174
Query: 683 VLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAHGSVLIKATHV----------- 728
+ E ++ DES +TGE P +K P G + + ++ T V
Sbjct: 175 LFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIG 234
Query: 729 -GNDTTLAQIVKLVEEAQMSKNP--------NKHIS-----------------QTEVIIR 762
G ++ ++ K+++ + K P K +S +++
Sbjct: 235 TGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEM 294
Query: 763 FAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKT 822
F S+ V I P L + + +G + ++K +E + DKT
Sbjct: 295 FTISVSLAVAAI--PEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKT 352
Query: 823 GTIT 826
GT+T
Sbjct: 353 GTLT 356
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 93.2 bits (230), Expect = 1e-18
Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1031
G++ I D + AV TL + GV + +ITGD+++TA AIA+++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1032 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1075
VF P HK+ ++ LQ G VAM GDGVND+ AL AD+GV
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1076 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1115
A+G TGTDV EAAD++L+ +D ++++I K I+
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/244 (20%), Positives = 91/244 (37%), Gaps = 48/244 (19%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E ++ ++L +L L E V G+ + + VP GD V + G + P D +
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLR 174
Query: 683 VLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAHGSVLIKATHV----------- 728
+ E ++ DES +TGE P +K P G + + ++ T V
Sbjct: 175 LFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIG 234
Query: 729 -GNDTTLAQIVKLVEEAQMSKNP--------NKHIS-----------------QTEVIIR 762
G ++ ++ K+++ + K P K +S +++
Sbjct: 235 TGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEM 294
Query: 763 FAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKT 822
F S+ V I P L + + +G + ++K +E + DKT
Sbjct: 295 FTISVSLAVAAI--PEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKT 352
Query: 823 GTIT 826
GT+T
Sbjct: 353 GTLT 356
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 93.2 bits (230), Expect = 1e-18
Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1031
G++ I D + AV TL + GV + +ITGD+++TA AIA+++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1032 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1075
VF P HK+ ++ LQ G VAM GDGVND+ AL AD+GV
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1076 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1115
A+G TGTDV EAAD++L+ +D ++++I K I+
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/244 (20%), Positives = 91/244 (37%), Gaps = 48/244 (19%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E ++ ++L +L L E V G+ + + VP GD V + G + P D +
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLR 174
Query: 683 VLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAHGSVLIKATHV----------- 728
+ E ++ DES +TGE P +K P G + + ++ T V
Sbjct: 175 LFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIG 234
Query: 729 -GNDTTLAQIVKLVEEAQMSKNP--------NKHIS-----------------QTEVIIR 762
G ++ ++ K+++ + K P K +S +++
Sbjct: 235 TGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEM 294
Query: 763 FAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKT 822
F S+ V I P L + + +G + ++K +E + DKT
Sbjct: 295 FTISVSLAVAAI--PEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKT 352
Query: 823 GTIT 826
GT+T
Sbjct: 353 GTLT 356
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 93.2 bits (230), Expect = 1e-18
Identities = 58/161 (36%), Positives = 86/161 (53%), Gaps = 28/161 (17%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINK----------- 1031
G++ I D + AV TL + GV + +ITGD+++TA AIA+++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1032 ----------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1075
VF P HK+ ++ LQ G VAM GDGVND+ AL AD+GV
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1076 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIR 1115
A+G TGTDV EAAD++L+ +D ++++I K I+
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK 700
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/244 (20%), Positives = 91/244 (37%), Gaps = 48/244 (19%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E ++ ++L +L L E V G+ + + VP GD V + G + P D +
Sbjct: 121 EYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLR 174
Query: 683 VLEGNTMA-DESLITGEAMPVTK--KPGSTVIAGSINAHGSVLIKATHV----------- 728
+ E ++ DES +TGE P +K P G + + ++ T V
Sbjct: 175 LFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIG 234
Query: 729 -GNDTTLAQIVKLVEEAQMSKNP--------NKHIS-----------------QTEVIIR 762
G ++ ++ K+++ + K P K +S +++
Sbjct: 235 TGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEM 294
Query: 763 FAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKT 822
F S+ V I P L + + +G + ++K +E + DKT
Sbjct: 295 FTISVSLAVAAI--PEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKT 352
Query: 823 GTIT 826
GT+T
Sbjct: 353 GTLT 356
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 86.7 bits (213), Expect = 1e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 31/158 (19%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-------- 1029
D G + + D + E A + G+ VV+ITGDN+ TA AI ++GI
Sbjct: 590 DLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVA 649
Query: 1030 -----------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
+ FA V P+HK V+ LQ+ + AM GDGVND+P
Sbjct: 650 GKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
AL +A++G+A+G+GT VA AA++VL ++ +VA++
Sbjct: 710 ALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAV 747
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 49/224 (21%)
Query: 666 GDIVKVVPGGKFPVDGKVLE---GNTMADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D +++E D+S++TGE++ VTK +
Sbjct: 148 GDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ G + A G T L +I + + + P + +S +I
Sbjct: 208 LFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGD 840
+ +++ +E + DKTGT+T V R+ ++ +
Sbjct: 328 RKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAE 371
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 85.1 bits (209), Expect = 4e-16
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G + + D + E A +V + G+ V++ITGDN+ TA AI ++GI
Sbjct: 594 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653
Query: 1030 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1071
+ FA V PSHK V+ LQ+ + AM GDGVND+PAL +A
Sbjct: 654 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713
Query: 1072 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
++G+A+G+GT VA A+++VL ++ +VA++
Sbjct: 714 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746
Score = 39.3 bits (90), Expect = 0.024
Identities = 47/232 (20%), Positives = 90/232 (38%), Gaps = 53/232 (22%)
Query: 666 GDIVKVVPGGKFPVDGKV--LEGNTM-ADESLITGEAMPVTKKPG-------------ST 709
GDIV++ G K P D ++ ++ T+ D+S++TGE++ V K +
Sbjct: 148 GDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ A G + G +T + +I + + + P + +S+ +I
Sbjct: 208 LFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 844
+ +++ +E + DKTGT+T V R+ +L GD +L
Sbjct: 328 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 85.1 bits (209), Expect = 4e-16
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G + + D + E A +V + G+ V++ITGDN+ TA AI ++GI
Sbjct: 594 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653
Query: 1030 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1071
+ FA V PSHK V+ LQ+ + AM GDGVND+PAL +A
Sbjct: 654 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713
Query: 1072 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
++G+A+G+GT VA A+++VL ++ +VA++
Sbjct: 714 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 746
Score = 39.3 bits (90), Expect = 0.024
Identities = 47/232 (20%), Positives = 90/232 (38%), Gaps = 53/232 (22%)
Query: 666 GDIVKVVPGGKFPVDGKV--LEGNTM-ADESLITGEAMPVTKKPG-------------ST 709
GDIV++ G K P D ++ ++ T+ D+S++TGE++ V K +
Sbjct: 148 GDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ A G + G +T + +I + + + P + +S+ +I
Sbjct: 208 LFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 844
+ +++ +E + DKTGT+T V R+ +L GD +L
Sbjct: 328 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSL 379
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
sapiens]
Length = 1015
Score = 85.1 bits (209), Expect = 4e-16
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 31/153 (20%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G + + D + E A +V + G+ V++ITGDN+ TA AI ++GI
Sbjct: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 626
Query: 1030 ------------------NKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQA 1071
+ FA V PSHK V+ LQ+ + AM GDGVND+PAL +A
Sbjct: 627 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 686
Query: 1072 DMGVAIGTGTDVAIEAADVVLIRNDLLDVVASI 1104
++G+A+G+GT VA A+++VL ++ +VA++
Sbjct: 687 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAV 719
Score = 32.3 bits (72), Expect = 2.9
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 763 FAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKT 822
+ F+ ++ + A P L T + +GT A+ +++ +E + DKT
Sbjct: 267 YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKT 326
Query: 823 GTITHGVPRVMRVLLL----GDVATL 844
GT+T V R+ +L GD +L
Sbjct: 327 GTLTTNQMSVCRMFILDRVEGDTCSL 352
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
sapiens]
Length = 994
Score = 85.1 bits (209), Expect = 4e-16
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 32/195 (16%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI---NK--- 1031
D G++ + D ++E ++ + G+ V++ITGDN+ TA AI ++GI N+
Sbjct: 590 DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVA 649
Query: 1032 -------------------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
FA V PSHK V+ LQ+ + AM GDGVND+P
Sbjct: 650 DRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNL 1126
AL +A++G+A+G+GT VA A+++VL ++ +VA++ + ++ + LI +
Sbjct: 710 ALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSN 768
Query: 1127 VGIPIAAGVFMPIGI 1141
VG + + +G+
Sbjct: 769 VGEVVCIFLTAALGL 783
Score = 40.4 bits (93), Expect = 0.011
Identities = 49/232 (21%), Positives = 89/232 (38%), Gaps = 53/232 (22%)
Query: 666 GDIVKVVPGGKFPVDGKVL--EGNTM-ADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D ++L + T+ D+S++TGE++ V K +
Sbjct: 148 GDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ A G L G T + +I + + K P + +S+ +I
Sbjct: 208 LFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 844
+ +++ +E + DKTGT+T V ++ ++ GD+ L
Sbjct: 328 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLL 379
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
sapiens]
Length = 1001
Score = 85.1 bits (209), Expect = 4e-16
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 32/195 (16%)
Query: 978 DGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI---NK--- 1031
D G++ + D ++E ++ + G+ V++ITGDN+ TA AI ++GI N+
Sbjct: 590 DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVA 649
Query: 1032 -------------------------VFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSP 1066
FA V PSHK V+ LQ+ + AM GDGVND+P
Sbjct: 650 DRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAP 709
Query: 1067 ALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNL 1126
AL +A++G+A+G+GT VA A+++VL ++ +VA++ + ++ + LI +
Sbjct: 710 ALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSN 768
Query: 1127 VGIPIAAGVFMPIGI 1141
VG + + +G+
Sbjct: 769 VGEVVCIFLTAALGL 783
Score = 40.4 bits (93), Expect = 0.011
Identities = 49/232 (21%), Positives = 89/232 (38%), Gaps = 53/232 (22%)
Query: 666 GDIVKVVPGGKFPVDGKVL--EGNTM-ADESLITGEAMPVTK-------------KPGST 709
GDIV+V G K P D ++L + T+ D+S++TGE++ V K +
Sbjct: 148 GDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNM 207
Query: 710 VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNP--------NKHISQTEVII 761
+ +G+ A G L G T + +I + + K P + +S+ +I
Sbjct: 208 LFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLI 267
Query: 762 RFA-------------------------FQTSITVLCIACPCSLGLATPTAVMVGTGVAA 796
A F+ ++ + A P L T + +GT A
Sbjct: 268 CVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 327
Query: 797 QNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLL----GDVATL 844
+ +++ +E + DKTGT+T V ++ ++ GD+ L
Sbjct: 328 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLL 379
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 84.0 bits (206), Expect = 8e-16
Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 28/154 (18%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAI------------------- 1023
G++ I D + AV L GV V +ITGD +TA AI
Sbjct: 570 GLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRNIGLCNGKLQAMSGEEV 629
Query: 1024 --------ATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV 1075
A +VG VF P HK+ ++ LQ G VAM GDGVND+ AL AD+G+
Sbjct: 630 DSVEKGELADRVGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGI 689
Query: 1076 AIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
A+G TGTDV+ EAA+++L+ +D ++ ++ K
Sbjct: 690 AMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGK 723
Score = 46.2 bits (108), Expect = 2e-04
Identities = 47/242 (19%), Positives = 94/242 (38%), Gaps = 42/242 (17%)
Query: 621 IIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVD 680
I E ++ ++L +L + E + G+ ++ E VP GD+V + G + P D
Sbjct: 150 IQEYRSEKSLEELTKMVPPECNCLREGKLQHLLARELVP------GDVVSLSIGDRIPAD 203
Query: 681 GKVLE-GNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHV----------- 728
++ E + + DES TGEA P +K G + +++ T V
Sbjct: 204 IRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVIG 263
Query: 729 -GNDTTLAQIVKLVEEAQMSKNPNK----HISQTEVIIRFA------------------- 764
G + ++ K+++ + K P + + + + F
Sbjct: 264 TGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSM 323
Query: 765 FQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGT 824
F +++ A P L + +++G A+ +++K +E + DKTGT
Sbjct: 324 FTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGT 383
Query: 825 IT 826
+T
Sbjct: 384 LT 385
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 80.1 bits (196), Expect = 1e-14
Identities = 70/243 (28%), Positives = 107/243 (44%), Gaps = 69/243 (28%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G++++ D + AV +S G+ V+++TGD+ TA+AIA VGI
Sbjct: 602 GLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAH 661
Query: 1030 ---------NK-------------------------------VFAEVLPSHKVAKVQELQ 1049
NK VFA P K+ V+ Q
Sbjct: 662 RLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQ 721
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASI---- 1104
+ VA+ GDGVNDSPAL +AD+G+A+G G+D A AAD+VL+ ++ +V +
Sbjct: 722 RQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGR 781
Query: 1105 ----HLSKRTVRRIRIN---LVLALIYNLVGIPIAAG----VFMPIGIVLQPWMGSAAMA 1153
+L K + N L LIY +VG+P+ G +F+ +G + P + A
Sbjct: 782 LIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEK 841
Query: 1154 ASS 1156
A S
Sbjct: 842 AES 844
Score = 39.3 bits (90), Expect = 0.024
Identities = 52/213 (24%), Positives = 77/213 (36%), Gaps = 37/213 (17%)
Query: 651 LIIREEQ---VPMELVQRGDIVKVVPGGKFPVDGKVLEG-NTMADESLITGEAMPVTKKP 706
L+IR+ + +P E + GDIV+V G + P D +VL D S +TGE+ P +
Sbjct: 185 LVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSS 244
Query: 707 GST----------VIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKNPNKHISQ 756
T + G+V + G+ T + I L K P +
Sbjct: 245 EFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIE 304
Query: 757 TEVIIRFAFQTSITVLCIACPCSLG----------------------LATPTAVMVGTGV 794
V I SI +L SL LAT T + T
Sbjct: 305 HFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAK 364
Query: 795 -AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
A+ L+K + +E + DKTGT+T
Sbjct: 365 RMAKKNCLVKNLEAVETLGSTSIICSDKTGTLT 397
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 78.2 bits (191), Expect = 5e-14
Identities = 59/200 (29%), Positives = 92/200 (46%), Gaps = 44/200 (22%)
Query: 977 IDGVLC-GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGIN----- 1030
+ G+ C ++ I D V+ E A+ Q G+ V ++TGDN TARAIAT+ GI
Sbjct: 671 VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGED 730
Query: 1031 --------------------------------KVFAEVLPSHKVAKVQEL-----QNKGK 1053
+V A P+ K V+ + ++ +
Sbjct: 731 FLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ 790
Query: 1054 KVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVR 1112
VA+ GDG ND PAL +AD+G A+G GTDVA EA+D++L ++ +V ++ +
Sbjct: 791 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 850
Query: 1113 RIRINLVLALIYNLVGIPIA 1132
I L L N+V + +A
Sbjct: 851 SISKFLQFQLTVNVVAVIVA 870
Score = 39.3 bits (90), Expect = 0.024
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 13/85 (15%)
Query: 657 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--------PG 707
Q+P+ + GDI +V G P DG +++GN + DES +TGE+ V K G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263
Query: 708 STVIAGSINAHGSVLIKATHVGNDT 732
+ V+ GS G +++ A V + T
Sbjct: 264 THVMEGS----GRMVVTAVGVNSQT 284
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 78.2 bits (191), Expect = 5e-14
Identities = 59/200 (29%), Positives = 92/200 (46%), Gaps = 44/200 (22%)
Query: 977 IDGVLC-GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGIN----- 1030
+ G+ C ++ I D V+ E A+ Q G+ V ++TGDN TARAIAT+ GI
Sbjct: 671 VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGED 730
Query: 1031 --------------------------------KVFAEVLPSHKVAKVQEL-----QNKGK 1053
+V A P+ K V+ + ++ +
Sbjct: 731 FLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ 790
Query: 1054 KVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVR 1112
VA+ GDG ND PAL +AD+G A+G GTDVA EA+D++L ++ +V ++ +
Sbjct: 791 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 850
Query: 1113 RIRINLVLALIYNLVGIPIA 1132
I L L N+V + +A
Sbjct: 851 SISKFLQFQLTVNVVAVIVA 870
Score = 39.3 bits (90), Expect = 0.024
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 13/85 (15%)
Query: 657 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--------PG 707
Q+P+ + GDI +V G P DG +++GN + DES +TGE+ V K G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263
Query: 708 STVIAGSINAHGSVLIKATHVGNDT 732
+ V+ GS G +++ A V + T
Sbjct: 264 THVMEGS----GRMVVTAVGVNSQT 284
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
Length = 1029
Score = 77.4 bits (189), Expect = 8e-14
Identities = 58/219 (26%), Positives = 101/219 (46%), Gaps = 59/219 (26%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIAT----------------- 1025
G+I++ D + AV +S G+ V+++TGD+ TA+AIA
Sbjct: 593 GLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAA 652
Query: 1026 --QVGINKV----------------------------------FAEVLPSHKVAKVQELQ 1049
++ I+KV FA P K+ V+ Q
Sbjct: 653 RLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQ 712
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
G VA+ GDGVNDSPAL +AD+G+A+G +G+DV+ +AAD++L+ ++ +V + +
Sbjct: 713 RLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGR 772
Query: 1109 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1142
++ +++ L N+ I I G+ +P+G +
Sbjct: 773 LIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTI 811
Score = 42.0 bits (97), Expect = 0.004
Identities = 49/240 (20%), Positives = 93/240 (38%), Gaps = 44/240 (18%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E+K+S+ + ++ +A V+ GE + Q+ ++ V GD+V++ G + P D +
Sbjct: 159 EAKSSKIMESFKNMVPQQALVIRGGE------KMQINVQEVVLGDLVEIKGGDRVPADLR 212
Query: 683 VLEG-NTMADESLITGEAMPVTKKPGST---------VIAGSIN-AHGSVLIKATHVGND 731
++ D S +TGE+ P ++ P T + S N G+ G+
Sbjct: 213 LISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDS 272
Query: 732 TTLAQIVKLVEEAQMSKNP----NKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTA 787
T + +I L + + P +H ++ A +T ++ G
Sbjct: 273 TVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVV--AVFLGVTFFALSLLLGYGWLEAII 330
Query: 788 VMVGTGVA---------------------AQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
++G VA A+ L+K + +E T+ DKTGT+T
Sbjct: 331 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 390
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 76.3 bits (186), Expect = 2e-13
Identities = 58/219 (26%), Positives = 96/219 (43%), Gaps = 59/219 (26%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVG-------------- 1028
G++++ D + AV ++ G+ V+++TGD+ TA+AIA VG
Sbjct: 598 GLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAA 657
Query: 1029 --------INK-------------------------------VFAEVLPSHKVAKVQELQ 1049
+N+ VFA P K+ V+ Q
Sbjct: 658 RLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQ 717
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
G VA+ GDGVNDSPAL +AD+GVA+G G+D A AAD++L+ ++ +V + +
Sbjct: 718 RLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGR 777
Query: 1109 RTVRRIRINLVLALIYNLVG-----IPIAAGVFMPIGIV 1142
++ ++ L N+ I I V +P+G +
Sbjct: 778 LIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCI 816
Score = 44.3 bits (103), Expect = 7e-04
Identities = 57/239 (23%), Positives = 93/239 (38%), Gaps = 42/239 (17%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E K++ +A +L +ATV+ G D I +Q+ + GD+V++ G + P D +
Sbjct: 162 EFKSTNIIASFKNLVPQQATVIRDG-DKFQINADQLVV-----GDLVEMKGGDRVPADIR 215
Query: 683 VLEG-NTMADESLITGEAMPVTKKPGST----------VIAGSINAHGSVLIKATHVGND 731
+L D S +TGE+ P T+ P T ++ G+V + G+
Sbjct: 216 ILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDR 275
Query: 732 TTLAQIVKLVEEAQMSKNP----NKHISQ--TEVIIRFAFQTSITVLCIA---------- 775
T + +I L + K P +H + I F I +CI
Sbjct: 276 TIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFF 335
Query: 776 -------CPCSLGLATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
P L LAT T + T A ++K + +E + DKTGT+T
Sbjct: 336 MAIVVAYVPEGL-LATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLT 393
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 75.9 bits (185), Expect = 2e-13
Identities = 58/219 (26%), Positives = 102/219 (46%), Gaps = 59/219 (26%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G++++ D + AV +S G+ V+++TGD+ TA+AIA VGI
Sbjct: 584 GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 643
Query: 1030 ----------------------------NKVFAEVLPSH------------KVAKVQELQ 1049
++ E+L +H K+ V+ Q
Sbjct: 644 RLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQ 703
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
+G VA+ GDGVNDSPAL +AD+G+A+G +G+DV+ +AAD++L+ ++ +V + +
Sbjct: 704 RQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGR 763
Query: 1109 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1142
++ ++ L N+ I I A + +P+G V
Sbjct: 764 LIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTV 802
Score = 45.8 bits (107), Expect = 3e-04
Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 40/238 (16%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E+K+S+ + ++ +A V+ GE I EE V GD+V+V G + P D +
Sbjct: 149 EAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVV------GDLVEVKGGDRVPADLR 202
Query: 683 VLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSIN-AHGSVLIKATHVGND 731
++ + D S +TGE+ P T+ P T + S N G+ G+
Sbjct: 203 IISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDR 262
Query: 732 TTLAQIVKLVEEAQMSKNP----NKHISQTEVIIRFAFQTSITVLCIACPCS-------- 779
T + +I L ++ + P +H Q + S VL + S
Sbjct: 263 TVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFL 322
Query: 780 LG----------LATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
+G LAT T + T A+ L+K + +E T+ DKTGT+T
Sbjct: 323 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 380
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 75.5 bits (184), Expect = 3e-13
Identities = 58/219 (26%), Positives = 101/219 (46%), Gaps = 59/219 (26%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI------------- 1029
G++++ D + AV +S G+ V+++TGD+ TA+AIA VGI
Sbjct: 577 GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636
Query: 1030 ----------------------------NKVFAEVLPSH------------KVAKVQELQ 1049
++ E+L +H K+ V+ Q
Sbjct: 637 RLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQ 696
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
+G VA+ GDGVNDSPAL +AD+GVA+G G+DV+ +AAD++L+ ++ +V + +
Sbjct: 697 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 756
Query: 1109 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1142
++ ++ L N+ I I A + +P+G +
Sbjct: 757 LIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTI 795
Score = 47.8 bits (112), Expect = 7e-05
Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 40/238 (16%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E+K+S+ + ++ +A V+ GE + QV E V GD+V++ G + P D +
Sbjct: 141 EAKSSKIMESFKNMVPQQALVIREGE------KMQVNAEEVVVGDLVEIKGGDRVPADLR 194
Query: 683 VLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSIN-AHGSVLIKATHVGND 731
++ + D S +TGE+ P T+ P T + S N G+ G+
Sbjct: 195 IISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDR 254
Query: 732 TTLAQIVKLVEEAQMSKNP----NKHISQTEVIIRFAFQTSITVLCI--------ACPCS 779
T + +I L ++ K P +H Q + S +L + A
Sbjct: 255 TVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFL 314
Query: 780 LG----------LATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
+G LAT T + T A+ L+K + +E T+ DKTGT+T
Sbjct: 315 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 372
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 75.1 bits (183), Expect = 4e-13
Identities = 57/192 (29%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 984 MIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-----------NKV 1032
++ I D V+ E A+ + G+ V ++TGDN TARAIAT+ GI K
Sbjct: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
Query: 1033 FAEVLPSHKVAKVQELQNK-------------------------------GKKVAMVGDG 1061
F ++ + K QE +K + VA+ GDG
Sbjct: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1062 VNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVL 1120
ND PAL +AD+G A+G GTDVA EA+D++L ++ +V ++ + I L
Sbjct: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 1121 ALIYNLVGIPIA 1132
L N+V + +A
Sbjct: 847 QLTVNVVAVIVA 858
Score = 39.3 bits (90), Expect = 0.024
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 657 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--PGSTVIAG 713
Q+P+ + GDI +V G P DG +++GN + DES +TGE+ V K +++G
Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Query: 714 SINAHGSVLIKATHVGNDTTLAQIVKLV 741
+ GS + T VG ++ I+ L+
Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLL 287
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 75.1 bits (183), Expect = 4e-13
Identities = 57/192 (29%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 984 MIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGI-----------NKV 1032
++ I D V+ E A+ + G+ V ++TGDN TARAIAT+ GI K
Sbjct: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
Query: 1033 FAEVLPSHKVAKVQELQNK-------------------------------GKKVAMVGDG 1061
F ++ + K QE +K + VA+ GDG
Sbjct: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1062 VNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVL 1120
ND PAL +AD+G A+G GTDVA EA+D++L ++ +V ++ + I L
Sbjct: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 1121 ALIYNLVGIPIA 1132
L N+V + +A
Sbjct: 847 QLTVNVVAVIVA 858
Score = 39.3 bits (90), Expect = 0.024
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 657 QVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTM-ADESLITGEAMPVTKK--PGSTVIAG 713
Q+P+ + GDI +V G P DG +++GN + DES +TGE+ V K +++G
Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Query: 714 SINAHGSVLIKATHVGNDTTLAQIVKLV 741
+ GS + T VG ++ I+ L+
Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLL 287
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
Length = 1023
Score = 74.3 bits (181), Expect = 7e-13
Identities = 59/219 (26%), Positives = 98/219 (44%), Gaps = 59/219 (26%)
Query: 983 GMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARA-----------------IAT 1025
G+I++ D + AV +S G+ V+++TGD+ TA+A IA
Sbjct: 587 GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 646
Query: 1026 QVGI------------------------------------NKVFAEVLPSHKVAKVQELQ 1049
++ I VFA P K+ V+ Q
Sbjct: 647 RLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQ 706
Query: 1050 NKGKKVAMVGDGVNDSPALAQADMGVAIG-TGTDVAIEAADVVLIRNDLLDVVASIHLSK 1108
+G VA+ GDGVNDSPAL +AD+GVA+G G+DV+ +AAD++L+ ++ +V + +
Sbjct: 707 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 766
Query: 1109 RTVRRIRINLVLALIYNLVGIP-----IAAGVFMPIGIV 1142
++ ++ L N+ I I A + +P+G V
Sbjct: 767 LIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 805
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/239 (24%), Positives = 97/239 (40%), Gaps = 42/239 (17%)
Query: 623 ESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGK 682
E+K+S+ + ++ +A V+ GE I EE V GD+V+V G + P D +
Sbjct: 151 EAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVV------GDLVEVKGGDRIPADLR 204
Query: 683 VLEGN-TMADESLITGEAMPVTKKPGST---------VIAGSIN-AHGSVLIKATHVGND 731
++ N D S +TGE+ P T+ P T + S N G+ + G+
Sbjct: 205 IISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDR 264
Query: 732 TTLAQIVKLVEEAQMSKNPNK-------HISQ------------TEVIIRFAFQTS---- 768
T + +I L + + P HI +I+ + + +
Sbjct: 265 TVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFL 324
Query: 769 ITVLCIACPCSLGLATPTAVMVGTGV-AAQNGILIKGGKPLEMAHKIKTVMFDKTGTIT 826
I ++ P L LAT T + T A+ L+K + +E T+ DKTGT+T
Sbjct: 325 IGIIVANVPEGL-LATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 382
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,417,468
Number of Sequences: 37866
Number of extensions: 1917129
Number of successful extensions: 5781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5441
Number of HSP's gapped (non-prelim): 252
length of query: 1258
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1144
effective length of database: 13,930,794
effective search space: 15936828336
effective search space used: 15936828336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.