Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 54792123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792123 complement component (3d/Epstein Barr virus)
receptor 2 isoform 1 [Homo sapiens]
(1092 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 2343 0.0
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 1481 0.0
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 489 e-138
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 464 e-130
gi|148886654 polydom [Homo sapiens] 420 e-117
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 353 6e-97
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 353 6e-97
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 333 7e-91
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 317 5e-86
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 278 2e-74
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 269 1e-71
gi|4502503 complement component 4 binding protein, alpha chain p... 248 2e-65
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 226 1e-58
gi|157419154 selectin P precursor [Homo sapiens] 218 2e-56
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 165 2e-40
gi|187960042 selectin E precursor [Homo sapiens] 159 2e-38
gi|27502413 CD46 antigen, complement regulatory protein isoform ... 143 1e-33
gi|27502402 CD46 antigen, complement regulatory protein isoform ... 143 1e-33
gi|27502425 CD46 antigen, complement regulatory protein isoform ... 143 1e-33
gi|27502423 CD46 antigen, complement regulatory protein isoform ... 143 1e-33
gi|27502419 CD46 antigen, complement regulatory protein isoform ... 141 3e-33
gi|27502427 CD46 antigen, complement regulatory protein isoform ... 141 3e-33
gi|27502411 CD46 antigen, complement regulatory protein isoform ... 140 9e-33
gi|27502409 CD46 antigen, complement regulatory protein isoform ... 140 9e-33
gi|27502405 CD46 antigen, complement regulatory protein isoform ... 140 9e-33
gi|27502421 CD46 antigen, complement regulatory protein isoform ... 137 4e-32
gi|27502417 CD46 antigen, complement regulatory protein isoform ... 137 4e-32
gi|27502415 CD46 antigen, complement regulatory protein isoform ... 137 4e-32
gi|27502407 CD46 antigen, complement regulatory protein isoform ... 137 4e-32
gi|24432108 CD46 antigen, complement regulatory protein isoform ... 137 4e-32
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 2343 bits (6073), Expect = 0.0
Identities = 1092/1092 (100%), Positives = 1092/1092 (100%)
Query: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE
Sbjct: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
Query: 61 KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT 120
KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT
Sbjct: 61 KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT 120
Query: 121 NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT 180
NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT
Sbjct: 121 NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT 180
Query: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF 240
YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF
Sbjct: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF 240
Query: 241 FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI
Sbjct: 241 FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
Query: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR
Sbjct: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
Query: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ 420
MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ
Sbjct: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ 420
Query: 421 KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT 480
KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT
Sbjct: 421 KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT 480
Query: 481 KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG 540
KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG
Sbjct: 481 KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG 540
Query: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV
Sbjct: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG
Sbjct: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP
Sbjct: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
Query: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 840
PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR
Sbjct: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 840
Query: 841 SPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVP 900
SPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVP
Sbjct: 841 SPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVP 900
Query: 901 TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWS 960
TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWS
Sbjct: 901 TCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWS 960
Query: 961 QPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 1020
QPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW
Sbjct: 961 QPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 1020
Query: 1021 NPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQKEAFHLEAR 1080
NPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQKEAFHLEAR
Sbjct: 1021 NPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTSQKEAFHLEAR 1080
Query: 1081 EVYSVDPYNPAS 1092
EVYSVDPYNPAS
Sbjct: 1081 EVYSVDPYNPAS 1092
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 1481 bits (3833), Expect = 0.0
Identities = 733/984 (74%), Positives = 768/984 (78%), Gaps = 98/984 (9%)
Query: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE
Sbjct: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
Query: 61 KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT 120
KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT
Sbjct: 61 KSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKT 120
Query: 121 NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT 180
NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT
Sbjct: 121 NFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVT 180
Query: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF 240
YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF
Sbjct: 181 YSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANF 240
Query: 241 FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI
Sbjct: 241 FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
Query: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR
Sbjct: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
Query: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ 420
MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ
Sbjct: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQ 420
Query: 421 KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT 480
KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT
Sbjct: 421 KEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT 480
Query: 481 KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG 540
KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG
Sbjct: 481 KPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG 540
Query: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV
Sbjct: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK- 659
QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK
Sbjct: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 660 GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGN-------------------- 699
CQ H R + V+ +C GY L G+
Sbjct: 661 TCQ------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 714
Query: 700 KSIHCMP-----------------------------------------------SGNWSP 712
K IHC P G+WS
Sbjct: 715 KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSG 774
Query: 713 SAPRCEETCQHVRQSLQELPAG----------SRVELVNTSCQDGYQLTGHAYQMCQDAE 762
+P+C + R E+ G S ++V C G+ + G C
Sbjct: 775 PSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH--T 832
Query: 763 NGIWFKKIPLC---KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
+ W +P C I C PPP NG HTG F G + Y CDQG+ L+GE L
Sbjct: 833 DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALL 892
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLN-KTHSAYSHNDIVYVDCNPG 878
C + G+WS P+P C C +P G + + Y + +V ++C G
Sbjct: 893 LCTHE----GTWSQPAPHCKE----VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG 944
Query: 879 FIMNGSRVIRCHTDNTWVPGVPTC 902
+++ GS +C +D+ W P + C
Sbjct: 945 YMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 1013 bits (2618), Expect = 0.0
Identities = 552/1047 (52%), Positives = 643/1047 (61%), Gaps = 134/1047 (12%)
Query: 149 VFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS----GKWS 204
V + C + P I NG + + IA G + YSC + L+GEK + C++ G W
Sbjct: 18 VLGISCGSPPPILNGRISYYST-PIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD 76
Query: 205 AVPPTCEEARCKSLGRFP----NGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 260
P CE S P K++ R G + F C + + G S C A
Sbjct: 77 KPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ-AN 135
Query: 261 QGVAWTKMPVCEEIF---CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFIL 317
T++P C +F CP+ P I NG H ++ +++ G VTY+C+ ++L
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCES------GYLL 189
Query: 318 IGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR---YTYNDT 374
+GE + C +G WS P CE +C GR +G+ T
Sbjct: 190 VGEKIINCL----SSGKWSAVPPTCE----EARCKS----LGRFPNGKVKEPPILRVGVT 237
Query: 375 VIFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKE-CQAPPNILNGQKEDRHMVRFDP 431
F C G+ L+G RC QG PVCE+ C +PP ILNG+ +
Sbjct: 238 ANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSY 297
Query: 432 GTSIKYSCNP------GYVLVGEESIQCTSE----GVWTPPVPQCKVAACEAT------- 474
G+ + Y+C+P ++L+GE +++CT + G W+ P P+C+++
Sbjct: 298 GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL 357
Query: 475 -GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVI 533
GR + + V +C G+ L GS C W +C++ C PP I
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNI 416
Query: 534 YNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
NG + F GT++ Y+CNPG + L+GE +I+CTS G W+ P P C
Sbjct: 417 LNGQKEDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTSE----GVWTPPVPQC 466
Query: 594 KLSL-------LAVQCSHVHI--------ANGYKISGK-------EAPYF---------- 621
K++ L + H + GYK+SG P+F
Sbjct: 467 KVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 622 ---------------------YNDTVTFKCYSG------FTLKGSSQIRCKADN----TW 650
Y TVT+ C G F+L G S IRC +++ TW
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 651 DPEIPVCEKGCQSPPGLH----HGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP 706
P+C+ + H +G G + TV + C G+ L G+ I C
Sbjct: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
Query: 707 SGNWSPSAPRCE-ETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI 765
W P P CE ETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI
Sbjct: 647 DNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI 706
Query: 766 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS 825
WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS
Sbjct: 707 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS 766
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR
Sbjct: 767 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 826
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL
Sbjct: 827 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 886
Query: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM
Sbjct: 887 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 946
Query: 1006 LEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNY 1065
LEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNY
Sbjct: 947 LEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNY 1006
Query: 1066 YTDTSQKEAFHLEAREVYSVDPYNPAS 1092
YTDTSQKEAFHLEAREVYSVDPYNPAS
Sbjct: 1007 YTDTSQKEAFHLEAREVYSVDPYNPAS 1033
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 489 bits (1259), Expect = e-138
Identities = 343/1129 (30%), Positives = 494/1129 (43%), Gaps = 157/1129 (13%)
Query: 29 ILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKY 88
+LNGR+ + + +G + + C F+L G + C+ ++ W+ P CE
Sbjct: 815 LLNGRV-LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAG-MESLWNSSVPVCEQI--- 869
Query: 89 SSCPEP-IVPGG-YKIRGSTPYRHGDSVTFACK------TNFSMNGNKSVWC----QANN 136
CP P ++P G + + + G +V + C T+F + G ++ C Q N
Sbjct: 870 -FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNG 928
Query: 137 MWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI-I 195
+W + P C + + P + T N G S+ Y C Y G I
Sbjct: 929 VWS-SPAPRCGILGHCQAPD-HFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSI 984
Query: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
CL + WS+ C+ CK+ NG V ++VG N+ C G+RL G S+
Sbjct: 985 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1044
Query: 256 CVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C+++G W TK P+C+ I C PP I NG I + N YGS+VTY C+P
Sbjct: 1045 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 1104
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
F L+GE ++ CT + + G WSGPAP+C + +C P + G +VS + ++ N+
Sbjct: 1105 FELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPPNVENGILVSDNRSLFSLNEV 1161
Query: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTS 434
V F C GF +KG ++++C A WEP P C + CQ PP++L+ ++ R F PG
Sbjct: 1162 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 1221
Query: 435 IKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTK----PQHQFVRPD 490
+ YSC PGY L G S++CT +G W+P P C+V +C+ QLL P + +
Sbjct: 1222 VFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAK 1281
Query: 491 VNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP 547
V+ C EG++L GS C W + +C++I CP PPVI NG HTG LE FP
Sbjct: 1282 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 1341
Query: 548 YGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL------------ 595
+G V YTC+P P+RG F LIGESTIRCTS+ Q G WS PAP C +
Sbjct: 1342 FGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 1401
Query: 596 SLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY------------------------ 631
+ L Q + G + + P +Y + C
Sbjct: 1402 AKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV 1461
Query: 632 ---------------------SGFTLKGSSQIRC-KADNT--WDPEIPVCEK-GCQSPPG 666
+G L G S C + NT W + P+C++ C PP
Sbjct: 1462 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1521
Query: 667 LHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNKSIHCMPS----GNWSPSAPR 716
+ +G N F G V Y C+ G + LVG SI+C + G WS AP+
Sbjct: 1522 IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1581
Query: 717 C--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKK 769
C C L + +R E+V CQ G+ + G CQ W +
Sbjct: 1582 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK--WEPE 1639
Query: 770 IPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG 829
+P C + C PPP I++G+HT +NF G EV Y C+ G+ L G L C G
Sbjct: 1640 LPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP----QG 1694
Query: 830 SWSGPSPQCLRSPPVTRCPN--PEVKHG---YKLNKTHSAYSHNDIVYVDCNPGFIMNGS 884
WS +P+C V C + ++ HG + LN A V C+ GF + GS
Sbjct: 1695 DWSPEAPRC----AVKSCDDFLGQLPHGRVLFPLNLQLGAK-----VSFVCDEGFRLKGS 1745
Query: 885 RVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCD- 940
V C + W VP C I CP PP NG HTG G I Y+CD
Sbjct: 1746 SVSHCVLVGMRSLWNNSVPVC---EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDP 1802
Query: 941 -----QGYLLVGEALLLCTHE----GTWSQPAPHC----KEVNCSSPADMDGIQKGLEPR 987
+ L+GE+ + CT + G WS PAP C + +C +P +
Sbjct: 1803 HPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1862
Query: 988 KM-YQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRSLAP 1034
+ G + EC GY G S C + W+ CR +S P
Sbjct: 1863 DFEFPVGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGP 1909
Score = 471 bits (1212), Expect = e-132
Identities = 368/1217 (30%), Positives = 515/1217 (42%), Gaps = 210/1217 (17%)
Query: 21 ISCGSPPPILNGRISYYSTPIAV---GTVIRYSCS-----GT-FRLIGEKSLLCITKDKV 71
I C SPP I NGR + P+ V G + Y+C GT F LIGE ++ C + +
Sbjct: 1319 IFCPSPPVIPNGR--HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQG 1376
Query: 72 DGTWDKPAPKC--------------------------------------EYFNKYSS--- 90
+G W PAP+C EY+ + S
Sbjct: 1377 NGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITC 1436
Query: 91 -----------------CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC- 132
C P P + T + G + ++C T + G+ S C
Sbjct: 1437 LDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECI 1496
Query: 133 -QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESG----- 186
N T+ P C + C P I NG S N + G VTY C G
Sbjct: 1497 LSGNTAHWSTKPPICQRI---PCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRK 1553
Query: 187 -YLLVGEKIINCLSS----GKWSAVPPTCEEARCKSLGRFPNGKV--KEPPILRVGVTAN 239
+ LVGE I C S+ G WS P C + NG + + +
Sbjct: 1554 VFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE 1613
Query: 240 FFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYG 298
F C G+ ++GP +C + W ++P C + C PP IL+G H + N S G
Sbjct: 1614 FRCQPGFVMKGPRRVKCQALNK---WEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPG 1669
Query: 299 SIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTS---AVQCPHPQ 355
V Y+C+P + L G ++L CT G WS APRC + + Q PH +
Sbjct: 1670 QEVFYSCEP------GYDLRGAASLHCT----PQGDWSPEAPRCAVKSCDDFLGQLPHGR 1719
Query: 356 ILRG-RMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWEPSAPVCEK-EC 410
+L + G K V F C GF LKGS C + W S PVCE C
Sbjct: 1720 VLFPLNLQLGAK--------VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFC 1771
Query: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNP------GYVLVGEESIQCTSE----GVWT 460
PP ILNG+ G I Y+C+P + L+GE +I+CTS+ GVW+
Sbjct: 1772 PNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWS 1831
Query: 461 PPVPQCKVAACEATGRQLLTKPQHQFVRPDV-------------NSSCGEGYKLSGSVYQ 507
P P+C+++ T Q F P + N C GY G ++
Sbjct: 1832 SPAPRCELS---VRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY--FGKMFS 1886
Query: 508 -ECQGTIPWFMEIRLCKEITCPPPPVIYNG-AHTGSSLEDFPYGTTVTYTCNPGPERGVE 565
C + W C+ +C PPP +NG H + D +G+TV Y+CN G
Sbjct: 1887 ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT---DTQFGSTVNYSCNEG------ 1937
Query: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS-HVHIANGYKISGKEAPYFYND 624
F LIG + C + TW AP+C++ + C I+NG S +
Sbjct: 1938 FRLIGSPSTTCLVSG-NNVTWDKKAPICEI----ISCEPPPTISNGDFYSNNRTSFHNGT 1992
Query: 625 TVTFKCYSG------FTLKGSSQIRCKADN----TWDPEIPVC--EKGCQSPPGLHHGRH 672
VT++C++G F L G I C + + W P C C +P + +
Sbjct: 1993 VVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPE-VENAIR 2051
Query: 673 TGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ------HVRQ 726
GN FF + + C PG+++VG+ ++ C +G W P P C CQ H
Sbjct: 2052 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 2111
Query: 727 SLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP-PPVIV 785
+L S + V SC+ Y L G A C G W + P C V C +
Sbjct: 2112 TLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC--TPQGDWSPEAPRCTVKSCDDFLGQLP 2169
Query: 786 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
+G+ ++ N G +VS+ CD+GF L G C W+ P C +
Sbjct: 2170 HGR--VLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM-KALWNSSVPVCEQ----I 2222
Query: 846 RCPNPEVKHGYKLNKTHSAYSHNDIVY-------VDCNPG----FIMNGSRVIRCHTD-- 892
CPNP LN H+ DI Y D +P F + G IRC +D
Sbjct: 2223 FCPNPPA----ILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQ 2278
Query: 893 --NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL 950
W P C CP PPK NG++ GG+++ + PGM+I Y CD GYLLVG+
Sbjct: 2279 GNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGF 2338
Query: 951 LLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSP 1010
+ CT +G WSQ +CKEVNCS P M+GI K LE +K+Y YG VTL+CEDGY LEGSP
Sbjct: 2339 IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSP 2398
Query: 1011 QSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTS 1070
SQCQ+D +W+PPLA C SR+ ++ G +G I LI+ ++I KHR N +
Sbjct: 2399 WSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENP 2458
Query: 1071 QKEAFHLEAREVYSVDP 1087
++ A HL ++ SV P
Sbjct: 2459 KEVAIHLHSQGGSSVHP 2475
Score = 455 bits (1171), Expect = e-128
Identities = 300/960 (31%), Positives = 430/960 (44%), Gaps = 126/960 (13%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G + Y C GY II CL + W+ C C++ NG V ++ G
Sbjct: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFG 124
Query: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
+ C +GYRL G S+ C+I+G V W + P+C+ I C PP I NG I + N
Sbjct: 125 SQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNREN 184
Query: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
YGS+VTY C+P F L+GE ++ CT + + G WSGPAP+C + +C P
Sbjct: 185 FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPP 241
Query: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
+ G +VS + ++ N+ V F C GF +KG ++++C A WEP P C + CQ PP
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 415 NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEAT 474
++L+ ++ R F PG + YSC PGY L G S++CT +G W+P P C+V +C+
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 475 GRQLLTK----PQHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITC 527
QLL P + + V+ C EG++L GS C W + +C++I C
Sbjct: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 421
Query: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
P PPVI NG HTG LE FP+G TV YTC+P P+RG F LIGESTIRCTS+ Q G WS
Sbjct: 422 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
Query: 588 GPAPLCKL------------SLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY---- 631
PAP C + + L Q + G + + P +Y + C
Sbjct: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV 541
Query: 632 -----------------------------------------SGFTLKGSSQIRCKADNT- 649
+G L G S C
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 650 --WDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNK 700
W + P+C++ C PP + +G N F G V Y C+PG + LVG
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 701 SIHCMPS----GNWSPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQ 749
SI+C + G WS AP+C C L + +R E+V CQ G+
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
Query: 750 LTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQ 809
+ G CQ W ++P C + C PPP +++ + T +NF G EV Y C+
Sbjct: 722 MKGPRRVKCQALNK--WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 778
Query: 810 GFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSH 867
G+ L G ++C G WS +P C V C + ++ +G L +
Sbjct: 779 GYDLRGAASMRCTP----QGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLGA 830
Query: 868 NDIVYVDCNPGFIMNGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGG 924
V C+ GF + GS C ++ W VP C + I CP PP PNG HTG
Sbjct: 831 K--VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ---IFCPSPPVIPNGRHTGK 885
Query: 925 NIARFSPGMSILYSCD------QGYLLVGEALLLCTHE----GTWSQPAPHCKEV-NCSS 973
+ F G ++ Y+CD + L+GE+ + CT + G WS PAP C + +C +
Sbjct: 886 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 945
Query: 974 PAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRS 1031
P + K + G + EC Y G P S C + W+ P VC+ +S
Sbjct: 946 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKS 1003
Score = 426 bits (1094), Expect = e-119
Identities = 337/1151 (29%), Positives = 474/1151 (41%), Gaps = 169/1151 (14%)
Query: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCSG------TFRLIGEKSLLCITKDKVDG 73
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 224 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
QA N W P LP+C V C P + + T + + +PG V YSCE GY L G
Sbjct: 281 QALNKWEP-ELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
+ C G WS PTCE C +G+ NG+V P L++G +F CDEG++L+G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
Query: 252 PSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
+S CV+AG W + +PVCE+IFCPSPP I NGRH G L +G V YTCDP P+
Sbjct: 396 SASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPD 455
Query: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
G +F LIGEST+RCT D Q G WS PAPRC + Q P + +
Sbjct: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI-LGHCQAPDHFLFAKLKTQTNASDFP 514
Query: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVR- 428
++ + C + + I C W VC+ K C+ PP+ +NG H++
Sbjct: 515 IGTSLKYECRPEYYGR-PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV---HVITD 570
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG---VWTPPVPQCKVAACE-----ATGRQLLT 480
G+ I YSC G+ L+G S +C G W+ P C+ C A G + T
Sbjct: 571 IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIST 630
Query: 481 KPQHQFVRPDVNSSCGEG------YKLSGSVYQECQGTIP----WFMEIRLCKEITCPPP 530
++ V C G ++L G C W C P
Sbjct: 631 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 690
Query: 531 PVIYNGAHTGSSLEDFPYGTTVTYTCNPG------------------------------- 559
P + NG + F V + C PG
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 750
Query: 560 -----------------PERGVEFS------LIGESTIRCTSNDQERGTWSGPAPLCKLS 596
P + V +S L G +++RCT +G WS AP C++
Sbjct: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT----PQGDWSPAAPTCEVK 806
Query: 597 LLAVQCSHVHIANGYKISGK---EAPYFYNDTVTFKCYSGFTLKGSSQIRC---KADNTW 650
C G ++G+ V F C GF LKGSS C ++ W
Sbjct: 807 ----SCDDF---MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLW 859
Query: 651 DPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDP------GYLLVGNKSIH 703
+ +PVCE+ C SPP + +GRHTG F G TV+YTCDP + L+G +I
Sbjct: 860 NSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIR 919
Query: 704 CM--PSGN--WSPSAPRCE--ETCQ----------HVRQSLQELPAGSRVELVNTSCQDG 747
C P GN WS APRC CQ + + + P G+ ++ C+
Sbjct: 920 CTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY---ECRPE 976
Query: 748 YQLTGHAYQM-CQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYE 806
Y G + + C D N +W +CK C PP VNG + + G+ ++Y
Sbjct: 977 YY--GRPFSITCLD--NLVWSSPKDVCKRKSCKTPPDPVNG--MVHVITDIQVGSRINYS 1030
Query: 807 CDQGFYLLGEKKLQC-RSDSKGHGSWSGPSPQCLRSPPVTRCP-NPEVKHGYKLNKTHSA 864
C G L+G +C S + H WS P C R P C P + +G ++
Sbjct: 1031 CTTGHRLIGHSSAECILSGNAAH--WSTKPPICQRIP----CGLPPTIANGDFISTNREN 1084
Query: 865 YSHNDIVYVDCNPG------FIMNGSRVIRCHTDN----TWVPGVPTCIKKAFIGCPPPP 914
+ + +V CNPG F + G I C +++ W P CI PP
Sbjct: 1085 FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI---IPNKCTPP 1141
Query: 915 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP 974
NG N + FS + + C G+++ G + C W P C V C P
Sbjct: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 1200
Query: 975 ADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAP 1034
D+ ++ + + G V CE GY L G+ +C W+P C +S
Sbjct: 1201 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 1260
Query: 1035 VLCGIAAGLIL 1045
+ + G +L
Sbjct: 1261 FMGQLLNGRVL 1271
Score = 338 bits (868), Expect = 1e-92
Identities = 220/671 (32%), Positives = 310/671 (46%), Gaps = 72/671 (10%)
Query: 404 PVCEKECQAP-------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE-SIQCTS 455
PV +C AP P L + E F GT + Y C PGY G SI C
Sbjct: 37 PVAWGQCNAPEWLPFARPTNLTDEFE------FPIGTYLNYECRPGY--SGRPFSIICLK 88
Query: 456 EGVWTPPVPQCKVAAC----EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC-- 509
VWT +C+ +C + + QF + SC +GY+L GS C
Sbjct: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCII 147
Query: 510 -QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
T+ W E +C I C PP I NG ++ E+F YG+ VTY CNPG F L
Sbjct: 148 SGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFEL 207
Query: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
+GE +I CTSND + G WSGPAP C ++ +C+ ++ NG +S + + N+ V F
Sbjct: 208 VGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 264
Query: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDY 688
+C GF +KG +++C+A N W+PE+P C + CQ PP + H T + F G V Y
Sbjct: 265 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 324
Query: 689 TCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQSL--------QELPAGSRVEL 739
+C+PGY L G S+ C P G+WSP+AP CE ++C L L G++V+
Sbjct: 325 SCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDF 384
Query: 740 VNTSCQDGYQLTGHAYQMCQDA-ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
V C +G+QL G + C A +W +P+C+ I C PPVI NG+HTG E F
Sbjct: 385 V---CDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 441
Query: 799 YGNEVSYECD------QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE- 851
+G V+Y CD F L+GE ++C SD +G+G WS P+P+C + C P+
Sbjct: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---GILGHCQAPDH 498
Query: 852 -VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 910
+ K S + + +C P + I C + W C +K+ C
Sbjct: 499 FLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKS---C 554
Query: 911 PPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT---WSQPAPHC 966
PP NG H I G I YSC G+ L+G + C G WS P C
Sbjct: 555 KTPPDPVNGMVHV---ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG------YMLEGSPQSQCQSDHQ- 1019
+ + C P + R+ + YG+VVT C G + L G P C S+
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 1020 ---WNPPLAVC 1027
W+ P C
Sbjct: 672 VGIWSGPAPQC 682
Score = 264 bits (674), Expect = 4e-70
Identities = 222/809 (27%), Positives = 328/809 (40%), Gaps = 114/809 (14%)
Query: 298 GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL 357
G+ + Y C P G S ++ K W+G RC + C +P
Sbjct: 66 GTYLNYECRP-----------GYSGRPFSIICLKNSVWTGAKDRCRRKS----CRNPPDP 110
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVCEK-ECQAP 413
MV K + + ++C G+ L GS C G W+ P+C++ C P
Sbjct: 111 VNGMVHVIKG-IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTSE----GVWTPPV 463
P I NG + F G+ + Y CNPG + LVGE SI CTS G+W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 464 PQC----KVAACEATGRQLLTKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFME 518
PQC K L++ + F + V C G+ + G +CQ W E
Sbjct: 230 PQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 289
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+ C + C PPP + + T ++F G V Y+C PG + L G +++RCT
Sbjct: 290 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG------YDLRGAASMRCTP 342
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK---EAPYFYNDTVTFKCYSGFT 635
+G WS AP C++ C G ++G+ V F C GF
Sbjct: 343 ----QGDWSPAAPTCEVK----SCDDFM---GQLLNGRVLFPVNLQLGAKVDFVCDEGFQ 391
Query: 636 LKGSSQIRCKA---DNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCD 691
LKGSS C ++ W+ +PVCE+ C SPP + +GRHTG F G TV+YTCD
Sbjct: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCD 451
Query: 692 P------GYLLVGNKSIHCM--PSGN--WSPSAPRCEET--CQ----------HVRQSLQ 729
P + L+G +I C P GN WS APRC CQ + +
Sbjct: 452 PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS 511
Query: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQM-CQDAENGIWFKKIPLCKVIHCHPPPVIVNGK 788
+ P G+ ++ C+ Y G + + C D N +W +CK C PP VNG
Sbjct: 512 DFPIGTSLKY---ECRPEYY--GRPFSITCLD--NLVWSSPKDVCKRKSCKTPPDPVNGM 564
Query: 789 HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC-RSDSKGHGSWSGPSPQCLRSPPVTRC 847
+ + G+ ++Y C G L+G +C S + H WS P C R P C
Sbjct: 565 VH--VITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH--WSTKPPICQRIP----C 616
Query: 848 P-NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WV 896
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 617 GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS 676
Query: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 677 GPAPQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
Query: 957 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 1016
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 734 NKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 792
Query: 1017 DHQWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
W+P C +S + + G +L
Sbjct: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVL 821
Score = 175 bits (443), Expect = 2e-43
Identities = 151/534 (28%), Positives = 220/534 (41%), Gaps = 89/534 (16%)
Query: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
+FP GT + Y C PG G FS+I C N W+G C+ C +
Sbjct: 62 EFPIGTYLNYECRPG-YSGRPFSII------CLKN----SVWTGAKDRCRRK----SCRN 106
Query: 605 --------VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN---TWDPE 653
VH+ G + + + + C G+ L GSS C WD E
Sbjct: 107 PPDPVNGMVHVIKGIQ---------FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNE 157
Query: 654 IPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNKSIHCMP 706
P+C++ C PP + +G N F G V Y C+PG + LVG SI+C
Sbjct: 158 TPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 707 S----GNWSPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQLTGHAY 755
+ G WS AP+C C L + +R E+V CQ G+ + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
Query: 756 QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLG 815
CQ W ++P C + C PPP +++ + T +NF G EV Y C+ G+ L G
Sbjct: 278 VKCQALNK--WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 334
Query: 816 EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSHNDIVYV 873
++C G WS +P C V C + ++ +G L + V
Sbjct: 335 AASMRCTP----QGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLGAK--VDF 384
Query: 874 DCNPGFIMNGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS 930
C+ GF + GS C ++ W VP C + I CP PP PNG HTG + F
Sbjct: 385 VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ---IFCPSPPVIPNGRHTGKPLEVFP 441
Query: 931 PGMSILYSCD------QGYLLVGEALLLCTHE----GTWSQPAPHCKEV-NCSSPAD-MD 978
G ++ Y+CD + L+GE+ + CT + G WS PAP C + +C +P +
Sbjct: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 501
Query: 979 GIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRS 1031
K + G + EC Y G P S C + W+ P VC+ +S
Sbjct: 502 AKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKS 553
Score = 100 bits (249), Expect = 8e-21
Identities = 79/327 (24%), Positives = 128/327 (39%), Gaps = 28/327 (8%)
Query: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
E P G+ +N C+ GY +G + + +N +W C+ C PP VNG
Sbjct: 62 EFPIGT---YLNYECRPGY--SGRPFSIIC-LKNSVWTGAKDRCRRKSCRNPPDPVNGMV 115
Query: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP- 848
+ + +G+++ Y C +G+ L+G C S W +P C R P C
Sbjct: 116 H--VIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETPICDRIP----CGL 168
Query: 849 NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WVPG 898
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 169 PPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP 228
Query: 899 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 958
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 229 APQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
Query: 959 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 1018
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 286 WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 1019 QWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
W+P C +S + + G +L
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVL 371
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 464 bits (1194), Expect = e-130
Identities = 356/1157 (30%), Positives = 503/1157 (43%), Gaps = 155/1157 (13%)
Query: 17 GVLGISCGSPPPILNGRISYYS--TPIAVGTVIRYSCSGTFRLIGEK-SLLCITKDKVDG 73
G+LG C +P L ++ + + +GT ++Y C + G S+ C+ +
Sbjct: 938 GILG-HCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD----NL 990
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC- 132
W P C K SC P P + T + G + ++C T + G+ S C
Sbjct: 991 VWSSPKDVC----KRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECI 1046
Query: 133 -QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESG----- 186
N T+ P C + C P I NG S N + G VTY C G
Sbjct: 1047 LSGNTAHWSTKPPICQRI---PCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRK 1103
Query: 187 -YLLVGEKIINCLSS----GKWSAVPPTCEEARCKSLGRFPNGKVKEP--PILRVGVTAN 239
+ LVGE I C S+ G WS P C + NG + + +
Sbjct: 1104 VFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE 1163
Query: 240 FFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYG 298
F C G+ ++GP +C + W ++P C + C PP IL+G H + N S G
Sbjct: 1164 FRCQPGFVMKGPRRVKCQALNK---WEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPG 1219
Query: 299 SIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTS---AVQCPHPQ 355
V Y+C+P + L G ++L CT G WS APRC + + Q PH +
Sbjct: 1220 QEVFYSCEP------GYDLRGAASLHCTPQ----GDWSPEAPRCAVKSCDDFLGQLPHGR 1269
Query: 356 ILRG-RMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVCEKE-C 410
+L + G K V F C GF LKGS C G W S PVCE C
Sbjct: 1270 VLFPLNLQLGAK--------VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFC 1321
Query: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTSE----GVWT 460
PP ILNG+ G I Y+C+P + L+GE +I+CTS+ GVW+
Sbjct: 1322 PNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWS 1381
Query: 461 PPVPQCKVAACEATGRQLLTKPQHQFVRPDV-------------NSSCGEGYKLSGSVYQ 507
P P+C+++ T Q F P + N C GY G ++
Sbjct: 1382 SPAPRCELSV---RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY--FGKMFS 1436
Query: 508 -ECQGTIPWFMEIRLCKEITCPPPPVIYNG-AHTGSSLEDFPYGTTVTYTCNPGPERGVE 565
C + W C+ +C PPP +NG H + D +G+TV Y+CN G
Sbjct: 1437 ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT---DTQFGSTVNYSCNEG------ 1487
Query: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVH-IANGYKISGKEAPYFYND 624
F LIG + C + TW AP+C++ + C I+NG S +
Sbjct: 1488 FRLIGSPSTTCLVSGNNV-TWDKKAPICEI----ISCEPPPTISNGDFYSNNRTSFHNGT 1542
Query: 625 TVTFKCYSG------FTLKGSSQIRCKADN----TWDPEIPVC--EKGCQSPPGLHHGRH 672
VT++C++G F L G I C + + W P C C +P + +
Sbjct: 1543 VVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPE-VENAIR 1601
Query: 673 TGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ------HVRQ 726
GN FF + + C PG+++VG+ ++ C +G W P P C CQ H
Sbjct: 1602 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEH 1661
Query: 727 SLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP-PPVIV 785
+L S + V SC+ Y L G A C G W + P C V C +
Sbjct: 1662 TLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC--TPQGDWSPEAPRCTVKSCDDFLGQLP 1719
Query: 786 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
+G+ ++ N G +VS+ CD+GF L G C W+ P C +
Sbjct: 1720 HGRV--LLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM-KALWNSSVPVCEQ----I 1772
Query: 846 RCPNPEVKHGYKLNKTHSAYSHNDIVY-------VDCNPG----FIMNGSRVIRCHTD-- 892
CPNP LN H+ DI Y D +P F + G IRC +D
Sbjct: 1773 FCPNPPAI----LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQ 1828
Query: 893 --NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL 950
W P C CP PPK NG++ GG+++ + PGM+I Y CD GYLLVG+
Sbjct: 1829 GNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGF 1888
Query: 951 LLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSP 1010
+ CT +G WSQ +CKEVNCS P M+GI K LE +K+Y YG VTL+CEDGY LEGSP
Sbjct: 1889 IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSP 1948
Query: 1011 QSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYYTDTS 1070
SQCQ+D +W+PPLA C SR+ ++ G +G I LI+ ++I KHR N +
Sbjct: 1949 WSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENP 2008
Query: 1071 QKEAFHLEAREVYSVDP 1087
++ A HL ++ SV P
Sbjct: 2009 KEVAIHLHSQGGSSVHP 2025
Score = 455 bits (1171), Expect = e-128
Identities = 300/960 (31%), Positives = 430/960 (44%), Gaps = 126/960 (13%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G + Y C GY II CL + W+ C C++ NG V ++ G
Sbjct: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFG 124
Query: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
+ C +GYRL G S+ C+I+G V W + P+C+ I C PP I NG I + N
Sbjct: 125 SQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNREN 184
Query: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
YGS+VTY C+P F L+GE ++ CT + + G WSGPAP+C + +C P
Sbjct: 185 FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPP 241
Query: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
+ G +VS + ++ N+ V F C GF +KG ++++C A WEP P C + CQ PP
Sbjct: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
Query: 415 NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEAT 474
++L+ ++ R F PG + YSC PGY L G S++CT +G W+P P C+V +C+
Sbjct: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
Query: 475 GRQLLTK----PQHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITC 527
QLL P + + V+ C EG++L GS C W + +C++I C
Sbjct: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 421
Query: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
P PPVI NG HTG LE FP+G TV YTC+P P+RG F LIGESTIRCTS+ Q G WS
Sbjct: 422 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
Query: 588 GPAPLCKL------------SLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY---- 631
PAP C + + L Q + G + + P +Y + C
Sbjct: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV 541
Query: 632 -----------------------------------------SGFTLKGSSQIRCKADNT- 649
+G L G S C
Sbjct: 542 WSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 650 --WDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNK 700
W + P+C++ C PP + +G N F G V Y C+PG + LVG
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 701 SIHCMPS----GNWSPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQ 749
SI+C + G WS AP+C C L + +R E+V CQ G+
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
Query: 750 LTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQ 809
+ G CQ W ++P C + C PPP +++ + T +NF G EV Y C+
Sbjct: 722 MKGPRRVKCQALNK--WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 778
Query: 810 GFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSH 867
G+ L G ++C G WS +P C V C + ++ +G L +
Sbjct: 779 GYDLRGAASMRCTP----QGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLGA 830
Query: 868 NDIVYVDCNPGFIMNGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGG 924
V C+ GF + GS C ++ W VP C + I CP PP PNG HTG
Sbjct: 831 K--VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ---IFCPSPPVIPNGRHTGK 885
Query: 925 NIARFSPGMSILYSCD------QGYLLVGEALLLCTHE----GTWSQPAPHCKEV-NCSS 973
+ F G ++ Y+CD + L+GE+ + CT + G WS PAP C + +C +
Sbjct: 886 PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 945
Query: 974 PAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRS 1031
P + K + G + EC Y G P S C + W+ P VC+ +S
Sbjct: 946 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKS 1003
Score = 416 bits (1070), Expect = e-116
Identities = 317/1078 (29%), Positives = 453/1078 (42%), Gaps = 119/1078 (11%)
Query: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCSG------TFRLIGEKSLLCITKDKVDG 73
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 224 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
QA N W P LP+C V C P + + T + + +PG V YSCE GY L G
Sbjct: 281 QALNKWEP-ELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
+ C G WS PTCE C +G+ NG+V P L++G +F CDEG++L+G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
Query: 252 PSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
+S CV+AG W + +PVCE+IFCPSPP I NGRH G L +G V YTCDP P+
Sbjct: 396 SASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPD 455
Query: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
G +F LIGEST+RCT D Q G WS PAPRC + Q P + +
Sbjct: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI-LGHCQAPDHFLFAKLKTQTNASDFP 514
Query: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVR- 428
++ + C + + I C W VC+ K C+ PP+ +NG H++
Sbjct: 515 IGTSLKYECRPEYYGR-PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV---HVITD 570
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG---VWTPPVPQCKVAACE-----ATGRQLLT 480
G+ I YSC G+ L+G S +C G W+ P C+ C A G + T
Sbjct: 571 IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIST 630
Query: 481 KPQHQFVRPDVNSSCGEG------YKLSGSVYQECQGTIP----WFMEIRLCKEITCPPP 530
++ V C G ++L G C W C P
Sbjct: 631 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 690
Query: 531 PVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPA 590
P + NG + F V + C PG F + G ++C Q W
Sbjct: 691 PNVENGILVSDNRSLFSLNEVVEFRCQPG------FVMKGPRRVKC----QALNKWEPEL 740
Query: 591 PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTW 650
P C V + + + + + V + C G+ L+G++ +RC W
Sbjct: 741 PSCS----RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW 796
Query: 651 DPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVS---GMTVDYTCDPGYLLVGNKSIHCMP 706
P P CE K C G+ G +F V+ G VD+ CD G+ L G+ + +C+
Sbjct: 797 SPAAPTCEVKSCDD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL 852
Query: 707 SGN---WSPSAPRCEE----------TCQHVRQSLQELPAGSRVELVNTSCQ------DG 747
+G W+ S P CE+ +H + L+ P G + VN +C
Sbjct: 853 AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG---KAVNYTCDPHPDRGTS 909
Query: 748 YQLTGHAYQMC--QDAENGIWFKKIPLCKVI-HCHPPPVIVNGK-HTGMMAENFLYGNEV 803
+ L G + C NG+W P C ++ HC P + K T A +F G +
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
Query: 804 SYECDQGFYLLGEK-KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTH 862
YEC +Y G + C + WS P C R C P ++
Sbjct: 970 KYECRPEYY--GRPFSITCLDNL----VWSSPKDVCKRK----SCKTPPDPVNGMVHVIT 1019
Query: 863 SAYSHNDIVYVDCNPGFIMNGSRVIRC-HTDNT--WVPGVPTCIKKAFIGCPPPPKTPNG 919
+ I Y C G + G C + NT W P C + I C PP NG
Sbjct: 1020 DIQVGSRINY-SCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR---IPCGLPPTIANG 1075
Query: 920 NHTGGNIARFSPGMSILYSCDQG------YLLVGEALLLCTHE----GTWSQPAPHCKEV 969
+ N F G + Y C+ G + LVGE + CT G WS PAP C
Sbjct: 1076 DFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 1135
Query: 970 NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 1027
N +P +++ + R ++ VV C+ G++++G + +CQ+ ++W P L C
Sbjct: 1136 NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 1193
Score = 338 bits (868), Expect = 1e-92
Identities = 220/671 (32%), Positives = 310/671 (46%), Gaps = 72/671 (10%)
Query: 404 PVCEKECQAP-------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE-SIQCTS 455
PV +C AP P L + E F GT + Y C PGY G SI C
Sbjct: 37 PVAWGQCNAPEWLPFARPTNLTDEFE------FPIGTYLNYECRPGY--SGRPFSIICLK 88
Query: 456 EGVWTPPVPQCKVAAC----EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC-- 509
VWT +C+ +C + + QF + SC +GY+L GS C
Sbjct: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCII 147
Query: 510 -QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
T+ W E +C I C PP I NG ++ E+F YG+ VTY CNPG F L
Sbjct: 148 SGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFEL 207
Query: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
+GE +I CTSND + G WSGPAP C ++ +C+ ++ NG +S + + N+ V F
Sbjct: 208 VGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 264
Query: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDY 688
+C GF +KG +++C+A N W+PE+P C + CQ PP + H T + F G V Y
Sbjct: 265 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 324
Query: 689 TCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQSL--------QELPAGSRVEL 739
+C+PGY L G S+ C P G+WSP+AP CE ++C L L G++V+
Sbjct: 325 SCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDF 384
Query: 740 VNTSCQDGYQLTGHAYQMCQDA-ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
V C +G+QL G + C A +W +P+C+ I C PPVI NG+HTG E F
Sbjct: 385 V---CDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 441
Query: 799 YGNEVSYECD------QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE- 851
+G V+Y CD F L+GE ++C SD +G+G WS P+P+C + C P+
Sbjct: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---GILGHCQAPDH 498
Query: 852 -VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 910
+ K S + + +C P + I C + W C +K+ C
Sbjct: 499 FLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKS---C 554
Query: 911 PPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT---WSQPAPHC 966
PP NG H I G I YSC G+ L+G + C G WS P C
Sbjct: 555 KTPPDPVNGMVHV---ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG------YMLEGSPQSQCQSDHQ- 1019
+ + C P + R+ + YG+VVT C G + L G P C S+
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 1020 ---WNPPLAVC 1027
W+ P C
Sbjct: 672 VGIWSGPAPQC 682
Score = 264 bits (674), Expect = 4e-70
Identities = 222/809 (27%), Positives = 328/809 (40%), Gaps = 114/809 (14%)
Query: 298 GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL 357
G+ + Y C P G S ++ K W+G RC + C +P
Sbjct: 66 GTYLNYECRP-----------GYSGRPFSIICLKNSVWTGAKDRCRRKS----CRNPPDP 110
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVCEK-ECQAP 413
MV K + + ++C G+ L GS C G W+ P+C++ C P
Sbjct: 111 VNGMVHVIKG-IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
Query: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTSE----GVWTPPV 463
P I NG + F G+ + Y CNPG + LVGE SI CTS G+W+ P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 464 PQC----KVAACEATGRQLLTKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFME 518
PQC K L++ + F + V C G+ + G +CQ W E
Sbjct: 230 PQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 289
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+ C + C PPP + + T ++F G V Y+C PG + L G +++RCT
Sbjct: 290 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG------YDLRGAASMRCTP 342
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK---EAPYFYNDTVTFKCYSGFT 635
+G WS AP C++ C G ++G+ V F C GF
Sbjct: 343 ----QGDWSPAAPTCEVK----SCDDFM---GQLLNGRVLFPVNLQLGAKVDFVCDEGFQ 391
Query: 636 LKGSSQIRCKA---DNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCD 691
LKGSS C ++ W+ +PVCE+ C SPP + +GRHTG F G TV+YTCD
Sbjct: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCD 451
Query: 692 P------GYLLVGNKSIHCM--PSGN--WSPSAPRCEET--CQ----------HVRQSLQ 729
P + L+G +I C P GN WS APRC CQ + +
Sbjct: 452 PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS 511
Query: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQM-CQDAENGIWFKKIPLCKVIHCHPPPVIVNGK 788
+ P G+ ++ C+ Y G + + C D N +W +CK C PP VNG
Sbjct: 512 DFPIGTSLKY---ECRPEYY--GRPFSITCLD--NLVWSSPKDVCKRKSCKTPPDPVNGM 564
Query: 789 HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC-RSDSKGHGSWSGPSPQCLRSPPVTRC 847
+ + G+ ++Y C G L+G +C S + H WS P C R P C
Sbjct: 565 VH--VITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH--WSTKPPICQRIP----C 616
Query: 848 P-NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WV 896
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 617 GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS 676
Query: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 677 GPAPQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
Query: 957 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 1016
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 734 NKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 792
Query: 1017 DHQWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
W+P C +S + + G +L
Sbjct: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVL 821
Score = 175 bits (443), Expect = 2e-43
Identities = 151/534 (28%), Positives = 220/534 (41%), Gaps = 89/534 (16%)
Query: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
+FP GT + Y C PG G FS+I C N W+G C+ C +
Sbjct: 62 EFPIGTYLNYECRPG-YSGRPFSII------CLKN----SVWTGAKDRCRRK----SCRN 106
Query: 605 --------VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN---TWDPE 653
VH+ G + + + + C G+ L GSS C WD E
Sbjct: 107 PPDPVNGMVHVIKGIQ---------FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNE 157
Query: 654 IPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNKSIHCMP 706
P+C++ C PP + +G N F G V Y C+PG + LVG SI+C
Sbjct: 158 TPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 707 S----GNWSPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQLTGHAY 755
+ G WS AP+C C L + +R E+V CQ G+ + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
Query: 756 QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLG 815
CQ W ++P C + C PPP +++ + T +NF G EV Y C+ G+ L G
Sbjct: 278 VKCQALNK--WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 334
Query: 816 EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSHNDIVYV 873
++C G WS +P C V C + ++ +G L + V
Sbjct: 335 AASMRCTP----QGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLGAK--VDF 384
Query: 874 DCNPGFIMNGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS 930
C+ GF + GS C ++ W VP C + I CP PP PNG HTG + F
Sbjct: 385 VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ---IFCPSPPVIPNGRHTGKPLEVFP 441
Query: 931 PGMSILYSCD------QGYLLVGEALLLCTHE----GTWSQPAPHCKEV-NCSSPAD-MD 978
G ++ Y+CD + L+GE+ + CT + G WS PAP C + +C +P +
Sbjct: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 501
Query: 979 GIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRS 1031
K + G + EC Y G P S C + W+ P VC+ +S
Sbjct: 502 AKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKS 553
Score = 100 bits (249), Expect = 8e-21
Identities = 79/327 (24%), Positives = 128/327 (39%), Gaps = 28/327 (8%)
Query: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
E P G+ +N C+ GY +G + + +N +W C+ C PP VNG
Sbjct: 62 EFPIGT---YLNYECRPGY--SGRPFSIIC-LKNSVWTGAKDRCRRKSCRNPPDPVNGMV 115
Query: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP- 848
+ + +G+++ Y C +G+ L+G C S W +P C R P C
Sbjct: 116 H--VIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETPICDRIP----CGL 168
Query: 849 NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WVPG 898
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 169 PPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP 228
Query: 899 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 958
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 229 APQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
Query: 959 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 1018
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 286 WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 1019 QWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
W+P C +S + + G +L
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVL 371
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 420 bits (1079), Expect = e-117
Identities = 329/1122 (29%), Positives = 461/1122 (41%), Gaps = 204/1122 (18%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
+ CG PP I+NG S + + G ++ YSC+ F + GEK C + G W P P
Sbjct: 2144 VRCGEPPSIMNGYAS--GSNYSFGAMVAYSCNKGFYIKGEKKSTC----EATGQWSSPIP 2197
Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
C SC EP + +T V + C + G+ CQAN W
Sbjct: 2198 TCHPV----SCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHS 2253
Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 200
CV PL+C P I NG EN G V + C GY LVG+ C S
Sbjct: 2254 ESPLMCV---PLDCGKPPPIQNGFMKGEN---FEVGSKVQFFCNEGYELVGDSSWTCQKS 2307
Query: 201 GKWSAVP-PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIA 259
GKW+ P C A+C N V + VGV F C EG+ LQGP +C+ +
Sbjct: 2308 GKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVT-FSCKEGHVLQGPSVLKCLPS 2366
Query: 260 GQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILI 318
Q W PVC+ + C PP I G I +S + +GS V Y+C F L
Sbjct: 2367 QQ---WNDSFPVCKIVLCTPPPLISFGVPIPSSALH--FGSTVKYSCVG------GFFLR 2415
Query: 319 GESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFA 378
G ST C D GTWS P P C V+CP P+ + ++ Q Y T ++
Sbjct: 2416 GNSTTLCQPD----GTWSSPLPECV----PVECPQPEEIPNGIIDVQG--LAYLSTALYT 2465
Query: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKE--DRHMVRFDPGTSI 435
C GF L G+ C G W P C+ EC P ILNG+ D H G ++
Sbjct: 2466 CKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHY-----GQTV 2520
Query: 436 KYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKP-QHQFVRPDVNS- 493
YSCN G+ L G ++ C G W P C C++ +P ++ FV S
Sbjct: 2521 TYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSP------QPIENGFVEGADYSY 2574
Query: 494 ------SCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA---------- 537
SC G++++G Q C+ + W I C I C PP I G
Sbjct: 2575 GAIIIYSCFPGFQVAGHAMQTCEES-GWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY 2633
Query: 538 -------------------HTGSSLE--------------DFPYGTTVTYTCNPGPERGV 564
H G+ + +F YGT V+YTCNPG
Sbjct: 2634 FEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPG----- 2688
Query: 565 EFSLIGESTIRCTSNDQERGTWSGPAPLCKL----------------------SLLAVQC 602
+ L+G + C QE GTW+G AP C S + C
Sbjct: 2689 -YELLGNPVLIC----QEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSC 2743
Query: 603 SHVHIANGYKI------------------------------SGKEAPYFYNDTVTFKCYS 632
HI G + S K + Y Y T+ ++C
Sbjct: 2744 KPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDP 2803
Query: 633 GFTLKGSSQIRCKADNTWDPEIPVC-EKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCD 691
G+ L G+ + C+ D WD + P+C C SPP +G+ G F ++YTC+
Sbjct: 2804 GYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTF---QKEIEYTCN 2860
Query: 692 PGYLLVGNKSIHCMPSGNWSPSAP-----RCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
G+LL G +S C+ +G+WS + P RC Q + L G E V C +
Sbjct: 2861 EGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKE-VTFHCHE 2919
Query: 747 GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYE 806
GY L G CQ +G W +IPLCK ++C PP + +G G +F++G + Y+
Sbjct: 2920 GYILHGAPKLTCQS--DGNWDAEIPLCKPVNCGPPEDLAHGFPNGF---SFIHGGHIQYQ 2974
Query: 807 CDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYS 866
C G+ L G +C S+ GSWSG SP CL RC P +++G +N T +
Sbjct: 2975 CFPGYKLHGNSSRRCLSN----GSWSGSSPSCLPC----RCSTPVIEYG-TVNGTD--FD 3023
Query: 867 HNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNI 926
+ C GF + G I C D W G P C C P PN + +
Sbjct: 3024 CGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHC---EHTSCGSLPMIPNAFISETSS 3080
Query: 927 ARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEP 986
+ + I YSC GY++ G + L+CT +G WSQP P C+ ++C SP + +
Sbjct: 3081 WKENV---ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP---PSVANAVAT 3134
Query: 987 RKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVC 1027
+ + Y + V L C +GY ++ + CQ D +W P C
Sbjct: 3135 GEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3176
Score = 381 bits (978), Expect = e-105
Identities = 319/1182 (26%), Positives = 475/1182 (40%), Gaps = 241/1182 (20%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
ISCG PPP+ NG + + G+ + Y C+ + L+G+ + C +G+W+ +P
Sbjct: 1688 ISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD----NGSWNGVSP 1741
Query: 81 KC-------------------------------EYFNKYSSCPEPI---VPGGYKIRGST 106
C Y +C EPI PG + S+
Sbjct: 1742 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSS 1801
Query: 107 P--YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLEC--PALPMIHN 162
Y G VTF+C+ + + G + C + W +P C +V C PA+P N
Sbjct: 1802 GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHL-IPYCKAV---SCGKPAIP--EN 1855
Query: 163 GHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFP 222
G E + + G VTY C GY L G+K +CL++ WS PP CE +C S
Sbjct: 1856 G--CIEEL-AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENIN 1912
Query: 223 NGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM-PVCEEIFCPSPPP 281
NGK + + TA++ CD GY LQGP C +G W + P C +FC PP
Sbjct: 1913 NGKYILSGLTYLS-TASYSCDTGYSLQGPSIIECTASG---IWDRAPPACHLVFCGEPPA 1968
Query: 282 ILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
I + GN N ++ + VTYTC +EG + L G T+ C D G WS +
Sbjct: 1969 IKDAVITGN---NFTFRNTVTYTC----KEG--YTLAGLDTIECLAD----GKWSRSDQQ 2015
Query: 342 CELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEP 401
C AV C P I+ S + + D + C G++L + Q+ CNAQG W P
Sbjct: 2016 C----LAVSCDEPPIV--DHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVP 2069
Query: 402 ----SAPVCEKE-CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSE 456
P C C+ PP++ E +F G+ + + C G+VL I+C
Sbjct: 2070 PEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRG 2129
Query: 457 GVWTP-PVP-QC----------------------------------------KVAACEAT 474
G W P P+ QC K + CEAT
Sbjct: 2130 GQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEAT 2189
Query: 475 GR---------------------QLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTI 513
G+ L + +V C GYK GS CQ
Sbjct: 2190 GQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANR 2249
Query: 514 PWFMEIRL-CKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
W E L C + C PP I NG G E+F G+ V + CN G + L+G+S
Sbjct: 2250 HWHSESPLMCVPLDCGKPPPIQNGFMKG---ENFEVGSKVQFFCNEG------YELVGDS 2300
Query: 573 TIRCTSNDQERGTWSGPA-PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY 631
+ C Q+ G W+ + P C + +C + + + VTF C
Sbjct: 2301 SWTC----QKSGKWNKKSNPKC----MPAKCPEPPLLENQLVLKELTTEV--GVVTFSCK 2350
Query: 632 SGFTLKGSSQIRCKADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
G L+G S ++C W+ PVC+ C PP + G + + F G TV Y+C
Sbjct: 2351 EGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHF--GSTVKYSC 2408
Query: 691 DPGYLLVGNKSIHCMPSGNWSPSAPRCEET-C---QHVRQSLQELPAGSRVELVNTSCQD 746
G+ L GN + C P G WS P C C + + + ++ + + +C+
Sbjct: 2409 VGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKP 2468
Query: 747 GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYE 806
G++L G+ +C ENG W P CK I C P I+NGK + + YG V+Y
Sbjct: 2469 GFELVGNTTTLC--GENGHWLGGKPTCKAIECLKPKEILNGKFS---YTDLHYGQTVTYS 2523
Query: 807 CDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE-VKHGYKLNKTHSAY 865
C++GF L G L C G W +P C C +P+ +++G+ + Y
Sbjct: 2524 CNRGFRLEGPSALTCLET----GDWDVDAPSC----NAIHCDSPQPIENGF---VEGADY 2572
Query: 866 SHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPP------------- 912
S+ I+ C PGF + G + C ++ W +PTC+ G PP
Sbjct: 2573 SYGAIIIYSCFPGFQVAGHAMQTCE-ESGWSSSIPTCM-PIDCGLPPHIDFGDCTKLKDD 2630
Query: 913 -------------PPKTPNGNHTGGNIAR---------------FSPGMSILYSCDQGYL 944
P TP+ + G +A+ F G + Y+C+ GY
Sbjct: 2631 QGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYE 2690
Query: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSP-ADMDGIQKGLEPRKMYQYGAVVTLECEDG 1003
L+G +L+C +GTW+ AP C + C P A +G + E G+ V C+ G
Sbjct: 2691 LLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTET----SMGSAVQYSCKPG 2746
Query: 1004 YMLEGSPQSQCQSDHQWNPPLAVCRSRSLA---PVLCGIAAG 1042
++L GS C + +W+ C + S PV+ G G
Sbjct: 2747 HILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKG 2788
Score = 370 bits (949), Expect = e-102
Identities = 317/1168 (27%), Positives = 465/1168 (39%), Gaps = 251/1168 (21%)
Query: 28 PILNGRISYYSTP---IAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEY 84
P L G + + T + G+ + C F+L+G C+ + G W +P P CE
Sbjct: 1632 PRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQ----GQWTQPLPHCER 1687
Query: 85 FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLP 144
+ P P+ G + + G +VT+ C + + G+ ++C N W P
Sbjct: 1688 IS--CGVPPPLENG---FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVS-P 1741
Query: 145 TCVSVF--------------------------------------PLECPALPMIHNGHHT 166
+C+ V P++C A NGH +
Sbjct: 1742 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSS 1801
Query: 167 SENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKV 226
E G VT+SC+ GY L+G I CL SG+W+ + P C+ C NG +
Sbjct: 1802 GE---IYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCI 1858
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP-VCEEIFCPSPPPILNG 285
+E G + C++GY L G S C+ +W+ P VCE + C SP I NG
Sbjct: 1859 EELAFT-FGSKVTYRCNKGYTLAGDKESSCLANS---SWSHSPPVCEPVKCSSPENINNG 1914
Query: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
++I L+ ++Y S +Y+CD + L G S + CT +G W P C L
Sbjct: 1915 KYI---LSGLTYLSTASYSCD------TGYSLQGPSIIECTA----SGIWDRAPPACHL- 1960
Query: 346 TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPV 405
V C P ++ +++G + +T+ +TV + C G+TL G I C A G W S
Sbjct: 1961 ---VFCGEPPAIKDAVITG--NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQ 2015
Query: 406 C-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPP-- 462
C C PP + + E H + G Y C+ GY L + C ++G W PP
Sbjct: 2016 CLAVSCDEPPIVDHASPETAHRLF---GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEG 2072
Query: 463 --VPQCKVAACE----ATGRQLLTKPQHQFVRPDVNS-SCGEGYKLSGSVYQECQGTIPW 515
+P+C CE + L + + +F V S C EG+ L+ S EC W
Sbjct: 2073 QDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQW 2132
Query: 516 F---MEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
M I+ C + C PP I NG +GS+ + +G V Y+CN G F + GE
Sbjct: 2133 NPSPMSIQ-CIPVRCGEPPSIMNGYASGSN---YSFGAMVAYSCNKG------FYIKGEK 2182
Query: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGY--KISGKEAPYFYNDTVTFK 629
C + G WS P P C V C + NG+ +G+ + V ++
Sbjct: 2183 KSTCEAT----GQWSSPIPTCH----PVSCGEPPKVENGFLEHTTGR----IFESEVRYQ 2230
Query: 630 CYSGFTLKGSSQIRCKADNTWDPEIPVC--EKGCQSPPGLHHGRHTGGNTVFFVSGMTVD 687
C G+ GS C+A+ W E P+ C PP + +G G N F G V
Sbjct: 2231 CNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN---FEVGSKVQ 2287
Query: 688 YTCDPGYLLVGNKSIHCMPSGNWSP-SAPRC------EETCQHVRQSLQELPAGSRVELV 740
+ C+ GY LVG+ S C SG W+ S P+C E + L+EL + V +V
Sbjct: 2288 FFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELT--TEVGVV 2345
Query: 741 NTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYG 800
SC++G+ L G + C ++ W P+CK++ C PPP+I G A +F G
Sbjct: 2346 TFSCKEGHVLQGPSVLKCLPSQQ--WNDSFPVCKIVLCTPPPLISFGVPIPSSALHF--G 2401
Query: 801 NEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE--------- 851
+ V Y C GF+L G C+ D G+WS P P+C+ PV CP PE
Sbjct: 2402 STVKYSCVGGFFLRGNSTTLCQPD----GTWSSPLPECV---PV-ECPQPEEIPNGIIDV 2453
Query: 852 ------------VKHGYKL--NKT----------------------------HSAYSHND 869
K G++L N T + +S+ D
Sbjct: 2454 QGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD 2513
Query: 870 IVY-----VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGG 924
+ Y CN GF + G + C W P+C I C P NG G
Sbjct: 2514 LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNA---IHCDSPQPIENGFVEG- 2569
Query: 925 NIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMD------ 978
A +S G I+YSC G+ + G A+ C G WS P C ++C P +D
Sbjct: 2570 --ADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTK 2626
Query: 979 -----------------------------GIQKGLEPRKM--------YQYGAVVTLECE 1001
+ K E K + YG +V+ C
Sbjct: 2627 LKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCN 2686
Query: 1002 DGYMLEGSPQSQCQSDHQWNPPLAVCRS 1029
GY L G+P CQ D WN C S
Sbjct: 2687 PGYELLGNPVLICQEDGTWNGSAPSCIS 2714
Score = 360 bits (924), Expect = 4e-99
Identities = 301/1040 (28%), Positives = 436/1040 (41%), Gaps = 133/1040 (12%)
Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
P I C P ILNG+ SY T + G + YSC+ FRL G +L C+ G W
Sbjct: 2491 PTCKAIECLKPKEILNGKFSY--TDLHYGQTVTYSCNRGFRLEGPSALTCLET----GDW 2544
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
D AP C + P+PI G + Y +G + ++C F + G+ C+ +
Sbjct: 2545 DVDAPSCNAI--HCDSPQPIENGFVE---GADYSYGAIIIYSCFPGFQVAGHAMQTCEES 2599
Query: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
W + +PTC+ P++C P I G T + GY E+
Sbjct: 2600 G-WSSS-IPTCM---PIDCGLPPHIDFGDCTK-------------LKDDQGYF---EQED 2638
Query: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
+ + + PP A K+ G ++ C+ GY L G P
Sbjct: 2639 DMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLI 2698
Query: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W P C I C P NG S GS V Y+C P
Sbjct: 2699 CQEDG---TWNGSAPSCISIECDLPTAPENGFL---RFTETSMGSAVQYSCKP------G 2746
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
IL G S LR ++++K WSG +PRCE A+ C P + + G YTY T
Sbjct: 2747 HILAG-SDLRLCLENRK---WSGASPRCE----AISCKKPNPVMNGSIKGSN--YTYLST 2796
Query: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGT 433
+ + C G+ L G+++ C W+ P+C +C +PP NGQ VR D T
Sbjct: 2797 LYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ------VRGDEYT 2850
Query: 434 ---SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQL---LTKPQHQFV 487
I+Y+CN G++L G S C + G W+ P C C AT QL +T+
Sbjct: 2851 FQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC-ATPPQLANGVTEGLDYGF 2909
Query: 488 RPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP 547
+V C EGY L G+ CQ W EI LCK + C PP + +G G S F
Sbjct: 2910 MKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFS---FI 2966
Query: 548 YGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 607
+G + Y C PG + L G S+ RC SN G+WSG +P C L +CS I
Sbjct: 2967 HGGHIQYQCFPG------YKLHGNSSRRCLSN----GSWSGSSPSC----LPCRCSTPVI 3012
Query: 608 ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GCQSPPG 666
G ++G + + +C+ GF L G S+I C+AD W P CE C S P
Sbjct: 3013 EYG-TVNGTD--FDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3069
Query: 667 LHHGRHTGGNTVFFVSGMT------VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE- 719
+ + F+S + + Y+C GY++ G+ + C G WS P CE
Sbjct: 3070 IPNA---------FISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3120
Query: 720 TC---QHVRQSLQELPAGSRVELVNTSCQDGYQL-TGHAYQMCQDAENGIWFKKIPLCKV 775
+C V ++ A + V C +GY + T CQ ++G WF + C
Sbjct: 3121 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQ--KDGRWFPERISCSP 3178
Query: 776 IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 835
C P+ N H + ++F +VS C +G+ G C+ D G+W P
Sbjct: 3179 KKC---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLD----GTWEPPF 3231
Query: 836 PQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT 894
SP C PE +HG+ + S Y+ + C PG+ + G+R C +
Sbjct: 3232 SDESCSP--VSCGKPESPEHGFVVG---SKYTFESTIIYQCEPGYELEGNRERVCQENRQ 3286
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT 954
W GV C + C P + NG +I + G +++YSC++GY L G + CT
Sbjct: 3287 WSGGVAICKETR---CETPLEFLNGK---ADIENRTTGPNVVYSCNRGYSLEGPSEAHCT 3340
Query: 955 HEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 1014
GTWS P P CK C P + + L K + V+++C +G++L+G C
Sbjct: 3341 ENGTWSHPVPLCKPNPCPVPFVIP--ENALLSEKEFYVDQNVSIKCREGFLLQGHGIITC 3398
Query: 1015 QSDHQWNPPLAVCRSRSLAP 1034
D W A C S P
Sbjct: 3399 NPDETWTQTSAKCEKISCGP 3418
Score = 357 bits (915), Expect = 4e-98
Identities = 295/1084 (27%), Positives = 440/1084 (40%), Gaps = 230/1084 (21%)
Query: 89 SSCPEPIVPGGYKIRGSTPY--------RHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
S CP ++ GS P+ + G V C F + GN +C W
Sbjct: 1629 SDCP--------RLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQ 1680
Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSS 200
LP C + C P + NG H++++ + G +VTY C +GY L+G+ + C +
Sbjct: 1681 P-LPHCERI---SCGVPPPLENGFHSADDFYA---GSTVTYQCNNGYYLLGDSRMFCTDN 1733
Query: 201 GKWSAVPPTC-----------------------------------------EEARCKSLG 219
G W+ V P+C E +CK+ G
Sbjct: 1734 GSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPG 1793
Query: 220 RFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM-PVCEEIFCPS 278
NG I VG F C EGY+L G C+ +G+ W + P C+ + C
Sbjct: 1794 NPENGH-SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE---WNHLIPYCKAVSCGK 1849
Query: 279 P----------------------------------------------PPIL--------- 283
P PP+
Sbjct: 1850 PAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPE 1909
Query: 284 ---NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
NG++I L+ ++Y S +Y+CD + L G S + CT +G W P
Sbjct: 1910 NINNGKYI---LSGLTYLSTASYSCD------TGYSLQGPSIIECTA----SGIWDRAPP 1956
Query: 341 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWE 400
C L V C P ++ +++G + +T+ +TV + C G+TL G I C A G W
Sbjct: 1957 ACHL----VFCGEPPAIKDAVITG--NNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWS 2010
Query: 401 PSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
S C C PP + + E H + G Y C+ GY L + C ++G W
Sbjct: 2011 RSDQQCLAVSCDEPPIVDHASPETAHRLF---GDIAFYYCSDGYSLADNSQLLCNAQGKW 2067
Query: 460 TPP----VPQCKVAACE----ATGRQLLTKPQHQFVRPDVNS-SCGEGYKLSGSVYQECQ 510
PP +P+C CE + L + + +F V S C EG+ L+ S EC
Sbjct: 2068 VPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM 2127
Query: 511 GTIPWF---MEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFS 567
W M I+ C + C PP I NG +GS ++ +G V Y+CN G F
Sbjct: 2128 RGGQWNPSPMSIQ-CIPVRCGEPPSIMNGYASGS---NYSFGAMVAYSCNKG------FY 2177
Query: 568 LIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH-VHIANGY--KISGKEAPYFYND 624
+ GE C + G WS P P C V C + NG+ +G+ +
Sbjct: 2178 IKGEKKSTC----EATGQWSSPIPTCH----PVSCGEPPKVENGFLEHTTGR----IFES 2225
Query: 625 TVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV--CEKGCQSPPGLHHGRHTGGNTVFFVS 682
V ++C G+ GS C+A+ W E P+ C PP + +G G N F
Sbjct: 2226 EVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN---FEV 2282
Query: 683 GMTVDYTCDPGYLLVGNKSIHCMPSGNWS-PSAPRC------EETCQHVRQSLQELPAGS 735
G V + C+ GY LVG+ S C SG W+ S P+C E + L+EL +
Sbjct: 2283 GSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELT--T 2340
Query: 736 RVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
V +V SC++G+ L G + C ++ W P+CK++ C PPP+I G A
Sbjct: 2341 EVGVVTFSCKEGHVLQGPSVLKCLPSQQ--WNDSFPVCKIVLCTPPPLISFGVPIPSSAL 2398
Query: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHG 855
+F G+ V Y C GF+L G C+ D G+WS P P+C+ PV CP PE
Sbjct: 2399 HF--GSTVKYSCVGGFFLRGNSTTLCQPD----GTWSSPLPECV---PV-ECPQPEEIPN 2448
Query: 856 YKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPK 915
++ AY + C PGF + G+ C + W+ G PTC KA I C P +
Sbjct: 2449 GIIDVQGLAYLSTAL--YTCKPGFELVGNTTTLCGENGHWLGGKPTC--KA-IECLKPKE 2503
Query: 916 TPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPA 975
NG + ++ G ++ YSC++G+ L G + L C G W AP C ++C SP
Sbjct: 2504 ILNGKFSYTDL---HYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSP- 2559
Query: 976 DMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPV 1035
I+ G Y YGA++ C G+ + G C+ + W+ + C P+
Sbjct: 2560 --QPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCE-ESGWSSSIPTC-----MPI 2611
Query: 1036 LCGI 1039
CG+
Sbjct: 2612 DCGL 2615
Score = 336 bits (862), Expect = 6e-92
Identities = 286/1025 (27%), Positives = 409/1025 (39%), Gaps = 150/1025 (14%)
Query: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74
AP I C SP PI NG + + G +I YSC F++ G C +
Sbjct: 2548 APSCNAIHCDSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-----EESG 2600
Query: 75 WDKPAPKCEYFN-------KYSSCPEPIVPGGY--------------------------- 100
W P C + + C + GY
Sbjct: 2601 WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKT 2660
Query: 101 -------KIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLE 153
S+ + +G V++ C + + GN + CQ + W + P+C+S+ E
Sbjct: 2661 WENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGS-APSCISI---E 2716
Query: 154 CPALPMIHNG--HHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCE 211
C NG T ++GS +V YSC+ G++L G + CL + KWS P CE
Sbjct: 2717 CDLPTAPENGFLRFTETSMGS-----AVQYSCKPGHILAGSDLRLCLENRKWSGASPRCE 2771
Query: 212 EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPV 270
CK NG +K + T + CD GY L G C W + P+
Sbjct: 2772 AISCKKPNPVMNGSIKGSNYTYLS-TLYYECDPGYVLNGTERRTC---QDDKNWDEDEPI 2827
Query: 271 CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQ 330
C + C SPP NG+ G+ ++ + YTC+ EG F+L G + C +
Sbjct: 2828 CIPVDCSSPPVSANGQVRGD---EYTFQKEIEYTCN----EG--FLLEGARSRVCLAN-- 2876
Query: 331 KTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQ 390
G+WSG P C V+C P L + G Y + V F C G+ L G+ +
Sbjct: 2877 --GSWSGATPDC----VPVRCATPPQLANGVTEGLD--YGFMKEVTFHCHEGYILHGAPK 2928
Query: 391 IRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
+ C + G W+ P+C+ C P ++ +G F G I+Y C PGY L G
Sbjct: 2929 LTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNG---FSFIHGGHIQYQCFPGYKLHGNS 2985
Query: 450 SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQF-VRPDVNSSCGEGYKLSGSVYQE 508
S +C S G W+ P C C + T F C +G+KL G
Sbjct: 2986 SRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEIT 3045
Query: 509 CQGTIPWFMEIRLCKEITCPPPPVIYNG--AHTGSSLEDFPYGTTVTYTCNPGPERGVEF 566
C+ W C+ +C P+I N + T S E+ +TY+C G +
Sbjct: 3046 CEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKEN-----VITYSCRSG------Y 3094
Query: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC-SHVHIANGYKISGKEAPYFYNDT 625
+ G S + CT E+G WS P P+C+ + C S +AN ++ EA + Y
Sbjct: 3095 VIQGSSDLICT----EKGVWSQPYPVCE----PLSCGSPPSVANA--VATGEA-HTYESE 3143
Query: 626 VTFKCYSGFTL-KGSSQIRCKADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSG 683
V +C G+T+ + C+ D W PE C K C P + H G + F
Sbjct: 3144 VKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDD---FSVN 3200
Query: 684 MTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELP-----AGSRVE 738
V +C GY G C G W P P +E+C V E P GS+
Sbjct: 3201 RQVSVSCAEGYTFEGVNISVCQLDGTWEP--PFSDESCSPVSCGKPESPEHGFVVGSKYT 3258
Query: 739 LVNT---SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
+T C+ GY+L G+ ++CQ EN W + +CK C P +NGK E
Sbjct: 3259 FESTIIYQCEPGYELEGNRERVCQ--ENRQWSGGVAICKETRCETPLEFLNGKAD---IE 3313
Query: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHG 855
N G V Y C++G+ L G + C +G+WS P P C +P CP P V
Sbjct: 3314 NRTTGPNVVYSCNRGYSLEGPSEAHCTE----NGTWSHPVPLCKPNP----CPVPFVIPE 3365
Query: 856 YKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPK 915
L Y + V + C GF++ G +I C+ D TW C K I C PP
Sbjct: 3366 NALLSEKEFYVDQN-VSIKCREGFLLQGHGIITCNPDETWTQTSAKCEK---ISCGPPAH 3421
Query: 916 TPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPA 975
N G + G I YSC GY+L G +C GTW+ P P C+ V C P
Sbjct: 3422 VENAIARG---VHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRAV-CRFPC 3476
Query: 976 DMDGI 980
GI
Sbjct: 3477 QNGGI 3481
Score = 313 bits (802), Expect = 6e-85
Identities = 252/933 (27%), Positives = 381/933 (40%), Gaps = 113/933 (12%)
Query: 148 SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVP 207
S+F +CP L + H + PG V C+ G+ LVG + CL+ G+W+
Sbjct: 1625 SIFCSDCPRLG--GSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPL 1682
Query: 208 PTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG--QGVAW 265
P CE C NG G T + C+ GY L G C G GV+
Sbjct: 1683 PHCERISCGVPPPLENG-FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1741
Query: 266 TKMPV--------CEE----------IFCPSPPPIL-NGRHI--------------GNSL 292
+ + V C E C PP +G++ G+S
Sbjct: 1742 SCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSS 1801
Query: 293 ANV-SYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQC 351
+ + G+ VT++C +EG + L+G + + C ++G W+ P C+ AV C
Sbjct: 1802 GEIYTVGAEVTFSC----QEG--YQLMGVTKITCL----ESGEWNHLIPYCK----AVSC 1847
Query: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
P I + ++ +T+ V + C G+TL G K+ C A +W S PVCE +C
Sbjct: 1848 GKPAIPENGCI--EELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKC 1905
Query: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
+P NI NG+ + ++ YSC+ GY L G I+CT+ G+W P C +
Sbjct: 1906 SSPENINNGKYILSGLTYL---STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVF 1962
Query: 471 C---EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
C A ++T F R V +C EGY L+G EC W + C ++C
Sbjct: 1963 CGEPPAIKDAVITGNNFTF-RNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 2021
Query: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
PP++ H +G Y C+ G +SL S + C + +G W
Sbjct: 2022 DEPPIV---DHASPETAHRLFGDIAFYYCSDG------YSLADNSQLLCNA----QGKWV 2068
Query: 588 GPAPLCKLSLLAVQCSH-VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
P +A C ++ S +A + V+FKC GF L S++I C
Sbjct: 2069 PPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMR 2128
Query: 647 DNTWDP---EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
W+P I C PP + +G +G N F G V Y+C+ G+ + G K
Sbjct: 2129 GGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSF---GAMVAYSCNKGFYIKGEKKST 2185
Query: 704 CMPSGNWSPSAPRCEETC----QHVRQSLQELPAGSRVEL-VNTSCQDGYQLTGHAYQMC 758
C +G WS P C V E G E V C GY+ G +C
Sbjct: 2186 CEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVC 2245
Query: 759 QDAENGIWFKKIPL-CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK 817
Q N W + PL C + C PP I NG M ENF G++V + C++G+ L+G+
Sbjct: 2246 Q--ANRHWHSESPLMCVPLDCGKPPPIQNG---FMKGENFEVGSKVQFFCNEGYELVGDS 2300
Query: 818 KLQCRSDSKGHGSWSGPS-PQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
C+ G W+ S P+C+ + +CP P + + K + +V C
Sbjct: 2301 SWTCQKS----GKWNKKSNPKCMPA----KCPEPPLLENQLVLK--ELTTEVGVVTFSCK 2350
Query: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 936
G ++ G V++C W P C + C PPP G + F G ++
Sbjct: 2351 EGHVLQGPSVLKCLPSQQWNDSFPVC---KIVLCTPPPLISFGVPIPSSALHF--GSTVK 2405
Query: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVV 996
YSC G+ L G + LC +GTWS P P C V C P + I G+ + Y +
Sbjct: 2406 YSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEE---IPNGIIDVQGLAYLSTA 2462
Query: 997 TLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRS 1029
C+ G+ L G+ + C + W C++
Sbjct: 2463 LYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2495
Score = 80.9 bits (198), Expect = 6e-15
Identities = 66/237 (27%), Positives = 98/237 (41%), Gaps = 44/237 (18%)
Query: 242 CDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIV 301
C EGYR G CE + CP+ P NG I N+ N + +
Sbjct: 362 CREGYRASGQ------------------TCELVHCPALKPPENGYFIQNTCNN-HFNAAC 402
Query: 302 TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRM 361
C P F L+G S + C + G WSG C + T CPH + +
Sbjct: 403 GVRCHP------GFDLVGSSIILCLPN----GLWSGSESYCRVRT----CPHLRQPKHGH 448
Query: 362 VSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVC-EKEC---QAPPN-I 416
+S Y T + AC G+ L+GS ++ C W+ P C E+ C Q P + I
Sbjct: 449 ISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVI 508
Query: 417 LNGQKEDRHMVRFDPGTSIKYSCNPGYVLVG-EESIQCTSEGVWTPPVPQCKVAACE 472
++ + +F GT SC G++L G +E ++CT+ G W V + A C+
Sbjct: 509 ISPHNCGKQPAKF--GTICYVSCRQGFILSGVKEMLRCTTSGKWNVGV---QAAVCK 560
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/301 (25%), Positives = 110/301 (36%), Gaps = 56/301 (18%)
Query: 630 CYSGFTLKGSSQIRCKA--DNTWDPE---------IPVCEKGCQSPPGLHHGRHTGGNTV 678
C G+ KG Q C A T+ PE IP ++ SPPG
Sbjct: 307 CEKGYYGKGL-QYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPG------------ 353
Query: 679 FFVSGMTVDYTCDPGYLLVGN--KSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSR 736
S D C GY G + +HC P+ + + TC + +
Sbjct: 354 ---STSPEDCVCREGYRASGQTCELVHC-PALKPPENGYFIQNTCNNHFNAA-------- 401
Query: 737 VELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 796
C G+ L G + +C NG+W C+V C +G H
Sbjct: 402 ---CGVRCHPGFDLVGSSIILC--LPNGLWSGSESYCRVRTCPHLRQPKHG-HISCSTRE 455
Query: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL-RSPPVTRCPNPEVKHG 855
LY CD+G+ L G KL C +G+ W GP P+C+ R + P +
Sbjct: 456 MLYKTTCLVACDEGYRLEGSDKLTC----QGNSQWDGPEPRCVERHCSTFQMPKDVIISP 511
Query: 856 YKLNKTHSAYSHNDIVYVDCNPGFIMNG-SRVIRCHTDNTWVPGVPTCIKKAF----IGC 910
+ K + + I YV C GFI++G ++RC T W GV + K I C
Sbjct: 512 HNCGKQPAKF--GTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINC 569
Query: 911 P 911
P
Sbjct: 570 P 570
Score = 72.0 bits (175), Expect = 3e-12
Identities = 72/286 (25%), Positives = 107/286 (37%), Gaps = 54/286 (18%)
Query: 439 CNPGYVLVGEESIQCTS--EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
C GY G + +CT+ G + P +++C + T P D C
Sbjct: 307 CEKGYYGKGLQ-YECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDC--VCR 363
Query: 497 EGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTC 556
EGY+ SG C+ + CP NG ++ + + C
Sbjct: 364 EGYRASGQT----------------CELVHCPALKPPENGYFIQNTCNNH-FNAACGVRC 406
Query: 557 NPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK 616
+PG F L+G S I C N G WSG C++ C H+ IS
Sbjct: 407 HPG------FDLVGSSIILCLPN----GLWSGSESYCRVRT----CPHLRQPKHGHISCS 452
Query: 617 EAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC-EKGC---QSPPGLHHGRH 672
Y T C G+ L+GS ++ C+ ++ WD P C E+ C Q P + H
Sbjct: 453 TREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPH 512
Query: 673 TGG------NTVFFVSGMTVDYTCDPGYLLVGNKS-IHCMPSGNWS 711
G T+ +VS C G++L G K + C SG W+
Sbjct: 513 NCGKQPAKFGTICYVS-------CRQGFILSGVKEMLRCTTSGKWN 551
Score = 71.2 bits (173), Expect = 5e-12
Identities = 74/292 (25%), Positives = 108/292 (36%), Gaps = 60/292 (20%)
Query: 787 GKHTG---MMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS-KGHGSWSGPSPQCL--- 839
G HTG + E YG + YEC C S + K GS G S C+
Sbjct: 297 GTHTGHFECICEKGYYGKGLQYECTA-----------CPSGTYKPEGSPGGIS-SCIPCP 344
Query: 840 ----RSPPVTRCPNPEV-KHGYKLNKTHSAYSH---------------------NDIVYV 873
SPP + P V + GY+ + H N V
Sbjct: 345 DENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGV 404
Query: 874 DCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGM 933
C+PGF + GS +I C + W C + P + P H +
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTC----PHLRQPKHGHISCSTREMLYKT 460
Query: 934 SILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSS---PAD--MDGIQKGLEPRK 988
+ L +CD+GY L G L C W P P C E +CS+ P D + G +P K
Sbjct: 461 TCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAK 520
Query: 989 MYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPL--AVCRSRSLAPVLC 1037
+G + + C G++L G + +C + +WN + AVC+ + C
Sbjct: 521 ---FGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINC 569
Score = 57.0 bits (136), Expect = 1e-07
Identities = 57/194 (29%), Positives = 80/194 (41%), Gaps = 27/194 (13%)
Query: 152 LECPALPMIHNGH---HTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPP 208
+ CPAL NG+ +T N + A G+ C G+ LVG II CL +G WS
Sbjct: 376 VHCPALKPPENGYFIQNTCNNHFNAACGVR----CHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 209 TCEEARCKSLGRFPNGKVK-EPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK 267
C C L + +G + + T CDEGYRL+G S + G
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEG--SDKLTCQGNSQWDGP 489
Query: 268 MPVCEEIFCPS----PPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIG-EST 322
P C E C + I++ + G A +G+I +C FIL G +
Sbjct: 490 EPRCVERHCSTFQMPKDVIISPHNCGKQPA--KFGTICYVSCRQ------GFILSGVKEM 541
Query: 323 LRCTVDSQKTGTWS 336
LRCT +G W+
Sbjct: 542 LRCTT----SGKWN 551
Score = 55.5 bits (132), Expect = 3e-07
Identities = 45/195 (23%), Positives = 74/195 (37%), Gaps = 15/195 (7%)
Query: 91 CPEPIVP-GGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSV 149
CP P GY I+ + + C F + G+ + C N +W + V
Sbjct: 378 CPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRT 437
Query: 150 FPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT 209
CP L +G H S + + + +C+ GY L G + C + +W P
Sbjct: 438 ----CPHLRQPKHG-HISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPR 492
Query: 210 CEEARC------KSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSS-RCVIAGQG 262
C E C K + P+ K+P + G C +G+ L G RC +G+
Sbjct: 493 CVERHCSTFQMPKDVIISPHNCGKQP--AKFGTICYVSCRQGFILSGVKEMLRCTTSGKW 550
Query: 263 VAWTKMPVCEEIFCP 277
+ VC+++ P
Sbjct: 551 NVGVQAAVCKDVEAP 565
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 22/161 (13%)
Query: 51 CSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGST-PYR 109
C F L+G +LC+ +G W C + +CP P I ST
Sbjct: 406 CHPGFDLVGSSIILCLP----NGLWSGSESYC----RVRTCPHLRQPKHGHISCSTREML 457
Query: 110 HGDSVTFACKTNFSMNGNKSVWCQANNMW-GPTRLPTCV----SVFPLECPALPMIHNGH 164
+ + AC + + G+ + CQ N+ W GP P CV S F + + HN
Sbjct: 458 YKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPE--PRCVERHCSTFQMPKDVIISPHNCG 515
Query: 165 HTSENVGSIAPGLSVTYSCESGYLLVGEK-IINCLSSGKWS 204
G+I SC G++L G K ++ C +SGKW+
Sbjct: 516 KQPAKFGTIC-----YVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 36.6 bits (83), Expect = 0.13
Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 7/110 (6%)
Query: 31 NGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-EYFNKYS 89
+G IS + + T +C +RL G L C + + WD P P+C E
Sbjct: 446 HGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC----QGNSQWDGPEPRCVERHCSTF 501
Query: 90 SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW-CQANNMW 138
P+ ++ + G P + G +C+ F ++G K + C + W
Sbjct: 502 QMPKDVIISPHNC-GKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKW 550
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 353 bits (905), Expect = 6e-97
Identities = 288/975 (29%), Positives = 421/975 (43%), Gaps = 106/975 (10%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C +P +G I T + +V+R++C FRL+G+ S +C WD P P C
Sbjct: 2529 CSTPESPPHGYI-ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK--SVWCQANNMW-G 139
+ SC P P I +T Y G VT+ C + ++ + + CQ++ W
Sbjct: 2588 QAI----SCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2642
Query: 140 PTRLPTCVSVFPLECPALP--MIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC 197
+ P CV V CP++ ++ +G N V +SC+ GY +G I C
Sbjct: 2643 HNKTPRCVVV---TCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIEC 2699
Query: 198 LSSGKWS--AVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
L +G WS P C+ C L PNG K G TA F CD G+ L G
Sbjct: 2700 LPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2758
Query: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C+ +G W++ C C P I+NG+ IG N Y V Y C+P
Sbjct: 2759 CLSSG---LWSESETRCLAGHCGIPELIVNGQVIGE---NYGYRDTVVYQCNP------G 2806
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK--DRYTYN 372
F LIG S C Q+ WSG P C V C HP G + G+ + + +N
Sbjct: 2807 FRLIGSSVRIC----QQDHNWSGQLPSC----VPVSCGHP----GSPIYGRTSGNGFNFN 2854
Query: 373 DTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDR-HMVRFD 430
D V F+C G+ ++G + +C A W P+C+ C P N ++E + F
Sbjct: 2855 DVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2914
Query: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLLTKPQHQFV 487
GT + Y CNPGY L G + C G W P+P+C + C G +L+ ++ F
Sbjct: 2915 YGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF- 2973
Query: 488 RPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCK---EITCPPPPVIYNGAHTGSSLE 544
V+ SC L G + CQ W C TC P +G+ S
Sbjct: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQES--- 3030
Query: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
+F +TV Y C+ G + L G C +N G+W+G P CK AVQC +
Sbjct: 3031 NFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECK----AVQCGN 3076
Query: 605 V-HIANG--YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC 661
ANG ++I G ++ +V + C G+ L G S +C A+ TW +P C
Sbjct: 3077 PGTTANGKVFRIDGTT----FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIIS 3132
Query: 662 QSPPGL-HHGRHTGGNTVFFVSGMTVDYTCDPGYL--LVGNKSIHCMPSGNWSPSAPRCE 718
PG+ +G G + +V G V Y C PGY L G++ C +G WS P C
Sbjct: 3133 CGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3189
Query: 719 E-TCQHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
TC Q G+ + ++ C GY+L+ A C NG W ++P C
Sbjct: 3190 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTC--VGNGTWSGEVPQCL 3247
Query: 775 VIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
C P + GK G ++F+Y +EVS+ C+ F L+G C++D G+WSG
Sbjct: 3248 PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQAD----GTWSGS 3300
Query: 835 SPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN 893
SP C+ P T C NP V +HG + N + +V C G ++ GS C D
Sbjct: 3301 SPHCI-EPTQTSCENPGVPRHGSQNNT--FGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL 3357
Query: 894 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEALLL 952
TW P CI + C P + N G ++ S G +++Y+C G+ L G +
Sbjct: 3358 TWSGIQPECIPHS---CKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTEHRV 3412
Query: 953 CTHEGTWSQPAPHCK 967
C + TW+ P C+
Sbjct: 3413 CRSDNTWTGKVPICE 3427
Score = 335 bits (860), Expect = 1e-91
Identities = 286/1071 (26%), Positives = 438/1071 (40%), Gaps = 137/1071 (12%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C PPP+ N I +G +IRY C F L+G L C +++ D P C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ--MDGAPPVC 2412
Query: 83 E--------------------YFNKYSS---CPEPI-VPGGYKI---------------- 102
+ Y + Y + C I V GY I
Sbjct: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2472
Query: 103 ------RGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
+P S ++ N + NG++ V+ Q + G + + C
Sbjct: 2473 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHE-VFLQWSADHGNNKKGFRIRYIAFYCST 2531
Query: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG----KWSAVPPTCEE 212
+G+ S+ G + V ++C+ G+ LVG+ C S W A P C+
Sbjct: 2532 PESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2589
Query: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT---KMP 269
C NG + L VG +FC++GYRL + V G W+ K P
Sbjct: 2590 ISCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDG-TWSNHNKTP 2647
Query: 270 VCEEIFCPSPPPIL--NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV 327
C + CPS + +GR + ++ Y + V ++CDP + +G +++ C
Sbjct: 2648 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDP------GYHGLGPASIECLP 2701
Query: 328 DSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
+ T +W P C++ S + P P G + Q +Y T IF C GF L G
Sbjct: 2702 NG--TWSWRNERPYCQI-ISCGELPTPP--NGNKIGTQT---SYGSTAIFTCDLGFMLVG 2753
Query: 388 SKQIRCNAQGTWEPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV 446
S C + G W S C C P I+NGQ + D ++ Y CNPG+ L+
Sbjct: 2754 SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRD---TVVYQCNPGFRLI 2810
Query: 447 GEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQ-HQFVRPD-VNSSCGEGYKLSGS 504
G C + W+ +P C +C G + + + F D V SC GY + G
Sbjct: 2811 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGP 2870
Query: 505 VYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE--DFPYGTTVTYTCNPGPER 562
+CQ W +CK + C P + N S +E +F YGT V Y CNPG
Sbjct: 2871 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE-SKIEHGNFTYGTVVFYDCNPG--- 2926
Query: 563 GVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFY 622
+ L G S + C Q G W P P C + + C H + +SG++ Y +
Sbjct: 2927 ---YFLFGSSVLIC----QPNGQWDKPLPEC----IMIDCGHPGVPPNAVLSGEK--YTF 2973
Query: 623 NDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG----CQSPPGLHHGRHTGGNTV 678
TV + C +L G S C+ + W P C C P HG N
Sbjct: 2974 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-- 3031
Query: 679 FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQH----VRQSLQELPA 733
F + TV Y CD GY+L G++ C+ +G+W+ P C+ C + + +
Sbjct: 3032 -FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3090
Query: 734 GSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMM 793
+ V SC +GY L+G + + C NG W +P C +I C P + NG G
Sbjct: 3091 TTFSSSVIYSCMEGYILSGPSVRQC--TANGTWSGTLPNCTIISCGDPGIPANGLRYG-- 3146
Query: 794 AENFLYGNEVSYECDQGF--YLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 851
++++ G VSY C G+ L G + C +G+WSG P C CP P
Sbjct: 3147 -DDYVVGQNVSYMCQPGYTMELNGSRIRTCTI----NGTWSGVMPTC----RAVTCPTPP 3197
Query: 852 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
+L T+ + + I Y+ C+PG+ ++ V+ C + TW VP C+ K F G P
Sbjct: 3198 QISNGRLEGTNFDWGFS-ISYI-CSPGYELSFPAVLTCVGNGTWSGEVPQCLPK-FCGDP 3254
Query: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
P G G + F + +SC+ ++LVG + +C +GTWS +PHC E
Sbjct: 3255 GIP--AQGKREGKS---FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
Query: 972 SSPADMDGIQKGLEPRKM-YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
+S + + G + +Q G+VV C+ G++L+GS C D W+
Sbjct: 3310 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS 3360
Score = 328 bits (840), Expect = 2e-89
Identities = 280/988 (28%), Positives = 400/988 (40%), Gaps = 105/988 (10%)
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
+K + Y Y S PE P GY I T + V +AC F + G S C+ +
Sbjct: 2516 NKKGFRIRYIAFYCSTPES-PPHGYII-SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKS 2573
Query: 136 NM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
+ W +P C ++ P P + G T++ + G VTY C GY L
Sbjct: 2574 SYGYHAWDAP-VPACQAI-SCGIPKAPT-NGGILTTDYL----VGTRVTYFCNDGYRLSS 2626
Query: 192 EKIIN--CLSSGKWSA--VPPTCEEARCKSLGRF----PNGKVKEPPILRVGVTANFFCD 243
+++ C S G WS P C C S+ F ++ F CD
Sbjct: 2627 KELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCD 2686
Query: 244 EGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
GY GP S C+ G + P C+ I C P NG IG SYGS +
Sbjct: 2687 PGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ---TSYGSTAIF 2743
Query: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVS 363
TCD + F+L+G + C +G WS RC A C P+++ V
Sbjct: 2744 TCD------LGFMLVGSAVRECL----SSGLWSESETRC----LAGHCGIPELIVNGQVI 2789
Query: 364 GQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKE 422
G+ Y Y DTV++ C GF L GS C W P C C P + + G+
Sbjct: 2790 GEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS 2847
Query: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKP 482
F+ + +SCN GY++ G QC + W+ P P CKV C G +K
Sbjct: 2848 GNG---FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKR 2904
Query: 483 QHQFVRPD------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
+ + + V C GY L GS CQ W + C I C P V N
Sbjct: 2905 ESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA 2964
Query: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
+G E + +G+TV Y+C + SL+G+S+ C N G WSG P C
Sbjct: 2965 VLSG---EKYTFGSTVHYSCTG------KRSLLGQSSRTCQLN----GHWSGSQPHCSGD 3011
Query: 597 LLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV 656
+G S +E+ + TV + C +G+ L GS + C A+ +W P
Sbjct: 3012 ATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPE 3068
Query: 657 CEKGCQSPPGLHHGRHTGGNTVFFVSGMT----VDYTCDPGYLLVGNKSIHCMPSGNWSP 712
C+ PG T VF + G T V Y+C GY+L G C +G WS
Sbjct: 3069 CKAVQCGNPGT-----TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSG 3123
Query: 713 SAPRCEE-TCQHVRQSLQELPAGSRVEL---VNTSCQDGY--QLTGHAYQMCQDAENGIW 766
+ P C +C L G + V+ CQ GY +L G + C NG W
Sbjct: 3124 TLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTC--TINGTW 3181
Query: 767 FKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK 826
+P C+ + C PP I NG+ G NF +G +SY C G+ L L C
Sbjct: 3182 SGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPGYELSFPAVLTC----V 3234
Query: 827 GHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV 886
G+G+WSG PQCL C +P + K + ++ + V CN FI+ GS
Sbjct: 3235 GNGTWSGEVPQCLPK----FCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFILVGSST 3288
Query: 887 IRCHTDNTWVPGVPTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
C D TW P CI+ C P P+ + N+T G F G + + C +G+L
Sbjct: 3289 RICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFG----FQVGSVVQFHCKKGHL 3344
Query: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGY 1004
L G C + TWS P C +C P + + +G + C+ G+
Sbjct: 3345 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGF 3402
Query: 1005 MLEGSPQSQ-CQSDHQWNPPLAVCRSRS 1031
L G + + C+SD+ W + +C + S
Sbjct: 3403 FLAGGTEHRVCRSDNTWTGKVPICEAGS 3430
Score = 281 bits (718), Expect = 3e-75
Identities = 235/798 (29%), Positives = 342/798 (42%), Gaps = 107/798 (13%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
ISCG P NG + T + G+ ++C F L+G C++ G W +
Sbjct: 2717 ISCGELPTPPNG--NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS----GLWSESET 2770
Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
+C + PE IV G ++ G Y + D+V + C F + G+ CQ ++ W
Sbjct: 2771 RC--LAGHCGIPELIVNG--QVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSG 2825
Query: 141 TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 198
+LP+CV P+ C P P+ N + VT+SC GYL+ G C
Sbjct: 2826 -QLPSCV---PVSCGHPGSPIYGRTSGNGFNFNDV-----VTFSCNIGYLMQGPTKAQCQ 2876
Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVK---EPPILRVGVTANFFCDEGYRLQGPPSSR 255
++ +WS PP C+ C G N K + E G + C+ GY L G
Sbjct: 2877 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
Query: 256 CVIAGQGVAWTK-MPVCEEIFC--PSPPP--ILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
C GQ W K +P C I C P PP +L+G ++GS V Y+C
Sbjct: 2937 CQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGE-------KYTFGSTVHYSCTGKRS 2986
Query: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
L+G+S+ C Q G WSG P C + C P S Q+ +
Sbjct: 2987 ------LLGQSSRTC----QLNGHWSGSQPHCSGDATGT-CGDPG--TPGHGSRQESNFR 3033
Query: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRF 429
TV +AC G+ L GS++ C A G+W P C+ +C P NG+ + R
Sbjct: 3034 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK-----VFRI 3088
Query: 430 DPGT---SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG--RQLLTKPQH 484
D T S+ YSC GY+L G QCT+ G W+ +P C + +C G L
Sbjct: 3089 DGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD 3148
Query: 485 QFVRPDVNSSCGEGY--KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
V +V+ C GY +L+GS + C W + C+ +TCP PP I NG G+
Sbjct: 3149 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT- 3207
Query: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
+F +G +++Y C+PG + L + + C N GTWSG P C L C
Sbjct: 3208 --NFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQC----LPKFC 3251
Query: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC----E 658
I K GK + Y V+F C F L GSS C+AD TW P C +
Sbjct: 3252 GDPGIPAQGKREGKS--FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
Query: 659 KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC- 717
C++P HG + NT F G V + C G+LL G+ + C+P WS P C
Sbjct: 3310 TSCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3367
Query: 718 ------EETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWFKKI 770
ET H +LP+ + +CQ G+ L G +++C+ + W K+
Sbjct: 3368 PHSCKQPETPAHANVVGMDLPSHGYTLIY--TCQPGFFLAGGTEHRVCR--SDNTWTGKV 3423
Query: 771 PLC----KVIHCHPPPVI 784
P+C K++ P P +
Sbjct: 3424 PICEAGSKILVKDPRPAL 3441
Score = 225 bits (573), Expect = 2e-58
Identities = 188/661 (28%), Positives = 270/661 (40%), Gaps = 75/661 (11%)
Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
P + +SCG P + GR S V+ +SC+ + + G C + + W
Sbjct: 2828 PSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQC----QANRQW 2881
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWC 132
P P C+ N C +P +P K + +G V + C + + G+ + C
Sbjct: 2882 SHPPPMCKVVN----CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2937
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Q N W LP C+ + +C + N + E G +V YSC L+G+
Sbjct: 2938 QPNGQWDKP-LPECIMI---DCGHPGVPPNAVLSGE---KYTFGSTVHYSCTGKRSLLGQ 2990
Query: 193 KIINCLSSGKWSAVPPTCE---EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
C +G WS P C C G +G +E R T + CD GY L
Sbjct: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH 3049
Query: 250 GPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
G C+ G +WT + P C+ + C +P NG+ + ++ S V Y+C
Sbjct: 3050 GSEERTCLANG---SWTGRQPECKAVQCGNPGTTANGKVF--RIDGTTFSSSVIYSC--- 3101
Query: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368
EG +IL G S +CT + GTWSG P C + + C P I + G D
Sbjct: 3102 -MEG--YILSGPSVRQCTAN----GTWSGTLPNCTI----ISCGDPGIPANGLRYG--DD 3148
Query: 369 YTYNDTVIFACMFGFT--LKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRH 425
Y V + C G+T L GS+ C GTW P C C PP I NG+ E
Sbjct: 3149 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG-- 3206
Query: 426 MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
FD G SI Y C+PGY L + C G W+ VPQC C G K + +
Sbjct: 3207 -TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGK 3265
Query: 486 --FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTG 540
+ +V+ SC + L GS + CQ W C E T C P V +G+
Sbjct: 3266 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3325
Query: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
+ F G+ V + C G L+ ST R D TWSG P C +
Sbjct: 3326 TF--GFQVGSVVQFHCKKG-------HLLQGSTTRTCLPDL---TWSGIQPEC----IPH 3369
Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADNTWDPEIPVCEK 659
C + G + P + T+ + C GF L G ++ R C++DNTW ++P+CE
Sbjct: 3370 SCKQPETPAHANVVGMDLP-SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3428
Query: 660 G 660
G
Sbjct: 3429 G 3429
Score = 206 bits (525), Expect = 7e-53
Identities = 158/570 (27%), Positives = 242/570 (42%), Gaps = 68/570 (11%)
Query: 491 VNSSCGEGYKLSGSVYQECQ----GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
V +C G++L G C+ G W + C+ I+C P NG G D+
Sbjct: 2552 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDY 2608
Query: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG--PAPLCKLSLLAVQCSH 604
GT VTY CN G S +T C S+ GTWS P C + V C
Sbjct: 2609 LVGTRVTYFCNDG----YRLSSKELTTAVCQSD----GTWSNHNKTPRC----VVVTCPS 2656
Query: 605 VH---IANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD--PEIPVCEK 659
++ + +G + Y Y V F C G+ G + I C + TW E P C+
Sbjct: 2657 INSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQI 2716
Query: 660 -GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE 718
C P +G G T + G T +TCD G++LVG+ C+ SG WS S RC
Sbjct: 2717 ISCGELPTPPNGNKIGTQTSY---GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC- 2772
Query: 719 ETCQHVRQSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKI 770
H + EL +V + V C G++L G + ++CQ N W ++
Sbjct: 2773 -LAGHC--GIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQL 2827
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
P C + C P + G+ +G F + + V++ C+ G+ + G K QC+++ +
Sbjct: 2828 PSCVPVSCGHPGSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ---- 2880
Query: 831 WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIR 888
WS P P C V C +P + K H +++ +V+ DCNPG+ + GS V+
Sbjct: 2881 WSHPPPMC----KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2936
Query: 889 CHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 948
C + W +P CI I C P PN +G +++ G ++ YSC L+G+
Sbjct: 2937 CQPNGQWDKPLPECI---MIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQ 2990
Query: 949 ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEG 1008
+ C G WS PHC + D G ++ + V C+ GY+L G
Sbjct: 2991 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHG 3050
Query: 1009 SPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
S + C ++ W C++ V CG
Sbjct: 3051 SEERTCLANGSWTGRQPECKA-----VQCG 3075
Score = 99.0 bits (245), Expect = 2e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 3184 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3237
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 3238 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3292
Query: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 3293 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3347
Query: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 3348 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3407
Query: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
R + WT K+P+CE +I P P L
Sbjct: 3408 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3441
Score = 82.0 bits (201), Expect = 3e-15
Identities = 214/1039 (20%), Positives = 328/1039 (31%), Gaps = 272/1039 (26%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKVKEPPI 231
G +VTY C++GY+L G + C+ W+ P+C A C S G V P
Sbjct: 1680 GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH-APCGSRSTGSEGTVLSP-- 1736
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFC-----PSPPPILNG 285
N+ V+ GQ V + T + E++ S L+G
Sbjct: 1737 ---NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1793
Query: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
H G SL S I P F + ++ R
Sbjct: 1794 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR--------------------- 1832
Query: 346 TSAVQC---PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGT 398
TS+ QC P P+ GR + + + +V+F C G+ L GS IRC N+
Sbjct: 1833 TSSTQCSSVPEPRF--GRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1887
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W S P C C IL +K GT + +PGY + ++ C V
Sbjct: 1888 WNDSLPTCIVPCGG---ILTKRK----------GTIL----SPGYPEPYDNNLNC----V 1926
Query: 459 WTPPVP-------QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-----KLSGSVY 506
W VP Q A E L P + S G S ++Y
Sbjct: 1927 WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLY 1986
Query: 507 QECQGTIP-----WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Q I + +E +CP P +G G + + G V++ C+ G
Sbjct: 1987 LNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCDQG-- 2041
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK---ISGKEA 618
+SL G S I C R + P L + S V ++ G+ S +
Sbjct: 2042 ----YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDC 2097
Query: 619 PYFYNDTVTFKCYSGFT-------------LKGSSQIRCKADNTWDPEIPVCE------- 658
+ N + F + F GSS+ P+IP
Sbjct: 2098 TWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHET 2157
Query: 659 ------------------------KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY 694
+ C P +G G + F G T+ + C PGY
Sbjct: 2158 SLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND---FTVGQTISFECFPGY 2214
Query: 695 LLVGNKSIHCM--PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 752
L+GN ++ C+ S NW+ PRCE C G+ + T GY
Sbjct: 2215 TLIGNSALTCLHGVSRNWNHPLPRCEALC-----------GGNITAMNGTIYSPGYPDEY 2263
Query: 753 HAYQMCQDAENGIWFKKIP-------LCKVIHCHPPPVIVN------------GKHTGMM 793
+Q C W ++P V+ P + G+ +G
Sbjct: 2264 PNFQDC------FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNT 2317
Query: 794 AENFLYGNE----VSYECD---QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTR 846
A +Y + + D GF++L Q R C PPV
Sbjct: 2318 ALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR--------------VCQPPPPV-- 2361
Query: 847 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT-DNTWVPGVPTCIKK 905
PN E+ + DI+ C PGF + G+ ++ C + + G P +
Sbjct: 2362 -PNAEIL------TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ- 2413
Query: 906 AFIGCPP----------------PPKTPN--------GNHTGGNIARFSPGMSILYSCDQ 941
+ CP P PN G NI F D
Sbjct: 2414 --VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDV 2471
Query: 942 GYLLVG---EALLLCTHEGTWSQP---APHCKEVNCSSPADMDGIQKGLEPRKMYQY--- 992
+ G ++ +L + G +S + EV AD +KG R + Y
Sbjct: 2472 LQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCST 2531
Query: 993 -----------------GAVVTLECEDGYMLEGSPQSQCQSD----HQWNPPLAVCRSRS 1031
+VV C+ G+ L G + C+ H W+ P+ C++ S
Sbjct: 2532 PESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS 2591
Query: 1032 LAPVLCGIAAGLILLTFLI 1050
G++ +L+
Sbjct: 2592 CGIPKAPTNGGILTTDYLV 2610
Score = 80.5 bits (197), Expect = 8e-15
Identities = 156/664 (23%), Positives = 237/664 (35%), Gaps = 164/664 (24%)
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEATGRQ---LLTKPQ 483
F G ++ +SC+ GY L G I C G VW+ P+P+C VA C A+ +L P
Sbjct: 1158 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPN 1216
Query: 484 HQFVRPDVNSSC--------GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
+ + + N C G+G +S + QG + ++I K+ T
Sbjct: 1217 YP-LNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---LKIYDGKDKTTH-----LL 1267
Query: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
GA TG+S+ G T++ T N + +EF N GT G L
Sbjct: 1268 GAFTGASMR----GLTLSSTSN---QLWLEF------------NSDTEGTDEG-FQLVYT 1307
Query: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD--NTWDP 652
S C I GYKIS + +F T+ + C G+TL GSS ++C WD
Sbjct: 1308 SFELSHCEDPGIPQFGYKIS--DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
Query: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM-----PS 707
+P C C GR G ++ +S PGY + ++ CM
Sbjct: 1366 PLPSCIAEC-------GGRFKGESSGRILS---------PGYPFPYDNNLRCMWMIEVDP 1409
Query: 708 GN--------------------WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDG 747
GN W P + + + SL S + +V
Sbjct: 1410 GNIVSLQFLAFDTEASHDILRVWD-GPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTD 1468
Query: 748 YQL--TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 805
+ + +G A Q C P V +NG G E G+ V +
Sbjct: 1469 FYISKSGFAIQFSSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVF 1512
Query: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH 862
+CD G+ L GE+++ C + W SPPV P N G+ L+
Sbjct: 1513 QCDPGYELQGEERITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNF 1564
Query: 863 -SAYSHNDIVYVDCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPP 912
Y H+ DC+ +N VI + D ++ P IG
Sbjct: 1565 PHPYPHSR----DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQ 1619
Query: 913 PPKTPNGNHTGGNIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
K P + N F S+ Y+ G+ L +A L +
Sbjct: 1620 DSKLPERIESSSNTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RES 1660
Query: 971 CSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLA 1025
C P + M+G + G++ Y+ G+ VT C+ GY+L+G C WN L
Sbjct: 1661 CFDPGNIMNGTRLGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
Query: 1026 VCRS 1029
C +
Sbjct: 1717 SCHA 1720
Score = 72.4 bits (176), Expect = 2e-12
Identities = 138/646 (21%), Positives = 228/646 (35%), Gaps = 124/646 (19%)
Query: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 1678 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1736
Query: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 1737 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1792
Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
+ L + SG + T+ F + T KG + ++ +
Sbjct: 1793 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1837
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 1838 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1894
Query: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
C + C +LTK + + P Y E P+ + +I
Sbjct: 1895 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1929
Query: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
T P V + H SL+ + G N P G + TSN
Sbjct: 1930 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1983
Query: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 1984 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 2040
Query: 633 GFTLKGSSQIRCKAD--NTWDPEIPVCEKGCQS----------PPGLHHGRHTGGNTVFF 680
G++L+G S I C W+ IP+C C PG G + +
Sbjct: 2041 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGF-PGNYPSSLDCTW 2099
Query: 681 VSGMTVDYTCDPGYLLVGNKSIHC---MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
+ + + ++ ++IH + SG+ S + + SL + +
Sbjct: 2100 TINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSL 2159
Query: 738 ELVNTSCQD--GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
+ Q+ G+ + AYQ+ C P NG ++
Sbjct: 2160 YFHSDYSQNKQGFHIVYQAYQLQS------------------CPDPRPFRNG---FVIGN 2198
Query: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPSPQC 838
+F G +S+EC G+ L+G L C HG +W+ P P+C
Sbjct: 2199 DFTVGQTISFECFPGYTLIGNSALTCL-----HGVSRNWNHPLPRC 2239
Score = 62.4 bits (150), Expect = 2e-09
Identities = 145/624 (23%), Positives = 214/624 (34%), Gaps = 142/624 (22%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 989 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 1041
Query: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
GY P S C V G+GV + + + E P
Sbjct: 1042 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1092
Query: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 1093 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1152
Query: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
NF + T C+ + GT WS P PRC A + IL
Sbjct: 1153 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1212
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Y N C++ ++ K I +A+ V + I
Sbjct: 1213 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1257
Query: 418 NGQKEDRHMVRFDPGTSIK----YSCNPGYVLVGEESIQCTSEG---VWTP-PVPQCKVA 469
+G+ + H++ G S++ S + L + T EG V+T + C+
Sbjct: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1317
Query: 470 ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ--GTIPWFMEIRLCKEITC 527
G ++ Q F + C GY L GS +C W + C C
Sbjct: 1318 GIPQFGYKI--SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAEC 1374
Query: 528 PPPPVIYNGAHTGSSLE---DFPYGTTV----TYTCNPGPERGVEFSLIGESTIRCTSND 580
+ G +G L FPY + +PG ++F S+D
Sbjct: 1375 GGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
Query: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640
R W GP + +L + S I G S DT + SGF ++ SS
Sbjct: 1428 ILR-VWDGPP---ENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS 1482
Query: 641 QIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
+ A DP +P+ +G G G TV + CDPGY L G +
Sbjct: 1483 SV---ATACRDPGVPM------------NGTRNGDGR---EPGDTVVFQCDPGYELQGEE 1524
Query: 701 SIHCMPSGN---WSPSAPRCEETC 721
I C+ N W PS P C C
Sbjct: 1525 RITCIQVENRYFWQPSPPVCIAPC 1548
Score = 58.9 bits (141), Expect = 3e-08
Identities = 134/619 (21%), Positives = 214/619 (34%), Gaps = 128/619 (20%)
Query: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 1160 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1217
Query: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Y N + V G I S H GD + T SM G
Sbjct: 1218 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
Query: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 1278 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1333
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 1334 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1379
Query: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 1380 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1436
Query: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 1437 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1481
Query: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 1482 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1538
Query: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
PS PVC C +G H + N YV+ S+ S
Sbjct: 1539 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1594
Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
+ P + + L+ Q + + SS ++ GSV
Sbjct: 1595 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1648
Query: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 1649 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1699
Query: 575 RCTSNDQERGTWSGPAPLC 593
C D R W+ P C
Sbjct: 1700 TCIMGDDGRPGWNRALPSC 1718
Score = 57.8 bits (138), Expect = 6e-08
Identities = 109/481 (22%), Positives = 163/481 (33%), Gaps = 115/481 (23%)
Query: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 1141 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1195
Query: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
C A C + G + P Y L + C+ + Q A
Sbjct: 1196 RC-VAECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAG--- 1236
Query: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
G +I +++ G ++ D + G S T+
Sbjct: 1237 ---------------KGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1281
Query: 329 SQKTGTW-------SGPAPRCELSTSAVQCPH------PQILRGRMVSGQKDRYTYNDTV 375
S W G +L ++ + H PQ G +S Q + T+
Sbjct: 1282 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ--GHFAGSTI 1337
Query: 376 IFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
I+ C G+TL GS ++C + W+ P C EC RF G
Sbjct: 1338 IYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RF-KGE 1381
Query: 434 SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----P 489
S +PGY + +++C +W V + + + T+ H +R P
Sbjct: 1382 SSGRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGP 1435
Query: 490 DVNSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPV 532
N + ++SGS+ E TI + + + K C P V
Sbjct: 1436 PENDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGV 1493
Query: 533 IYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPL 592
NG G E G TV + C+PG + L GE I C + R W P+
Sbjct: 1494 PMNGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCI-QVENRYFWQPSPPV 1543
Query: 593 C 593
C
Sbjct: 1544 C 1544
Score = 54.3 bits (129), Expect = 6e-07
Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 48/286 (16%)
Query: 631 YSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
Y+GF L+ +++R + C P + +G G + + G TV Y C
Sbjct: 1646 YTGFHLEYKAKLR---------------ESCFDPGNIMNGTRLGMD---YKLGSTVTYYC 1687
Query: 691 DPGYLLVGNKSIHCMPSGN----WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
D GY+L G ++ C+ + W+ + P C C GS +++ +
Sbjct: 1688 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC-------GSRSTGSEGTVLSPNYPK 1740
Query: 747 GYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 804
Y + GH Y + E ++ + + +H V + G ++ L +
Sbjct: 1741 NYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH------DVVEVYDGPTQQSSLLSSLSG 1793
Query: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQCLRSPPVTRCPN-PEVKHGYKLNKT 861
+ L ++ R S G + G Q + T+C + PE + G ++
Sbjct: 1794 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG-- 1851
Query: 862 HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGVPTCI 903
+ ++ V DCNPG+I++GS IRC T W +PTCI
Sbjct: 1852 -NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1896
Score = 51.2 bits (121), Expect = 5e-06
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 59/252 (23%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P + V+G+ G +F G+ VS+ CD G+ L E+ L C K H WS P P
Sbjct: 970 CLDPGIPVHGRRYG---HDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHW-WSHPLPT 1022
Query: 838 C-------LRSPPVTRC--------PNP-------EVKHGYKLN---KTHSAYSHNDIVY 872
C +R P T PN +V HG + T H+D +
Sbjct: 1023 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1082
Query: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA--FIG--------------------C 910
+ N F +R+ T G+ + FI C
Sbjct: 1083 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1142
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHCKE 968
P G+ G N F G ++ +SC GY L G + ++C G WS P P C
Sbjct: 1143 EDPGIPQYGSRIGFN---FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
Query: 969 VNCSSPADMDGI 980
+S + +GI
Sbjct: 1200 ECGASATNNEGI 1211
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/414 (21%), Positives = 146/414 (35%), Gaps = 88/414 (21%)
Query: 616 KEAPYFYN-DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV----CEKGCQSPPGL--- 667
+E F N D + F+C GF L G I C+ +N W IP+ C +P G
Sbjct: 635 REGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLS 694
Query: 668 -HHGRHTGGN-----TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
+ G N T+ G + + + + L + G+ SP +P T
Sbjct: 695 PDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFT 752
Query: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
V L S ++ Q + ++G + + + C
Sbjct: 753 GAEVPSHLT-----SNSHILRLEFQADHSMSGRGFNITYNTFGHN-----------ECPD 796
Query: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCL 839
P + +N + G +NF G+ +S C++GF G + + C G WSG P+C
Sbjct: 797 PGIPINARRFG---DNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCG 852
Query: 840 R------SPPVTRCPNP----------------EVKHGYKLNKTHSAYS---HNDIVYVD 874
S P +P E + G+ + T + + D++ V
Sbjct: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 912
Query: 875 CNPGFIM------NGSRV------------IRCHTDNTWVP-GVPTCIKKAFIG---CPP 912
P + NG++V + TDN+ G + + C
Sbjct: 913 DGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLD 972
Query: 913 PPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
P +G G + FS G ++ +SCD GY L E LLC WS P P C
Sbjct: 973 PGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1023
Score = 45.8 bits (107), Expect = 2e-04
Identities = 221/1045 (21%), Positives = 335/1045 (32%), Gaps = 223/1045 (21%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG P L G + V+R+ C F LIGEKS++C + + W P
Sbjct: 623 SCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPI 676
Query: 82 C------EYFNKYSSCPEPIVPGGYK---------IRGSTPYRHGDSVTFACKTNFSMNG 126
C + + P P GY I H F ++ F
Sbjct: 677 CIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLA 736
Query: 127 NKSVWCQANNMWG-------PTRLPTCVSVFPLECPA--------LPMIHN--GHHTSEN 169
K + + G P+ L + + LE A + +N GH+ +
Sbjct: 737 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 796
Query: 170 VG----------SIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPPTCEEARC 215
G + G S++ CE G++ G + I C L GK WS + P C A C
Sbjct: 797 PGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC-GAPC 855
Query: 216 KSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIF 275
P+G + P G+ S C + + + E F
Sbjct: 856 GGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSIKITFERF 900
Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRCTVDSQKT 332
+ H G +L + GS Y P+ NFI L T D+ ++
Sbjct: 901 QTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLFTTDNSRS 952
Query: 333 GTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQ 390
+G E ++ + C P I + GR ++ TV F+C G+ L +
Sbjct: 953 N--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEP 1007
Query: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEES 450
+ C W P C+ C VR GT + +PGY S
Sbjct: 1008 LLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGYPEFYPNS 1050
Query: 451 IQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLSGS----- 504
+ CT WT V K + + H ++ N S + +L+GS
Sbjct: 1051 LNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPT 1104
Query: 505 ----VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSSLEDFPYG 549
+Y + + + + + E IT C P + G+ G +F G
Sbjct: 1105 INAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF---NFGIG 1161
Query: 550 TTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIAN 609
T+T++C+ G + L G S I C R WS P P C +C N
Sbjct: 1162 DTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAECGASATNN 1208
Query: 610 GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLH- 668
+ P Y + +C ++ I A + V + H
Sbjct: 1209 EGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHL 1266
Query: 669 HGRHTGGNTVFFVSGMTVDYT--------------CDPGYLLV--GNKSIHCMPSGNWSP 712
G TG + + G+T+ T D G+ LV + HC P
Sbjct: 1267 LGAFTGAS----MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE-----DP 1317
Query: 713 SAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPL 772
P+ + S Q AGS + C GY L G + C E W +P
Sbjct: 1318 GIPQF-----GYKISDQGHFAGSTIIY---GCNPGYTLHGSSLLKCMTGERRAWDYPLPS 1369
Query: 773 CKVIHCHPPPVIVNGKHTGMMAE---NFLYGNEV----SYECDQG-FYLLGEKKLQCRSD 824
C + C G+ +G + F Y N + E D G L +
Sbjct: 1370 C-IAECGGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1425
Query: 825 SKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGS 884
W GP + ++ PE H LN + + Y+ + I S
Sbjct: 1426 HDILRVWDGPPENDMLLKEISGSLIPEGIHS-TLNIVTIQFDTD--FYISKSGFAIQFSS 1482
Query: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
V D PGVP NG G PG ++++ CD GY
Sbjct: 1483 SVATACRD----PGVPM----------------NGTRNGDG---REPGDTVVFQCDPGYE 1519
Query: 945 LVGEALLLC---THEGTWSQPAPHC 966
L GE + C + W P C
Sbjct: 1520 LQGEERITCIQVENRYFWQPSPPVC 1544
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 903 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 958
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 439 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 495
Query: 959 WSQPAPHCKEVNCSS 973
WS P CK C S
Sbjct: 496 WSDHRPVCKVKTCGS 510
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/251 (20%), Positives = 95/251 (37%), Gaps = 37/251 (14%)
Query: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKGC 661
+I NG ++ Y TVT+ C +G+ L+G S + C + W+ +P C C
Sbjct: 1666 NIMNGTRLG---MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC 1722
Query: 662 QS----------PPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP---SG 708
S P G N V+ ++ + ++ G + S+H + G
Sbjct: 1723 GSRSTGSEGTVLSPNYPKNYSVGHNCVYSIA-VPKEFVVF-GQFVFFQTSLHDVVEVYDG 1780
Query: 709 NWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK 768
S+ + H +SL L +G+++ + TS +T + ++
Sbjct: 1781 PTQQSSLLSSLSGSHSGESL-PLSSGNQITIRFTSVG---PITAKGFHFV--------YQ 1828
Query: 769 KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGH 828
+P C P G+ G F G+ V ++C+ G+ L G ++C +
Sbjct: 1829 AVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1885
Query: 829 GSWSGPSPQCL 839
W+ P C+
Sbjct: 1886 AQWNDSLPTCI 1896
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGR 476
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R
Sbjct: 153 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMR 206
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 137 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
Query: 82 C 82
C
Sbjct: 195 C 195
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 446 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
Query: 838 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 885
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 503 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 561
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
+ G P + + G P I S M + D+
Sbjct: 562 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 609
Query: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 610 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 655
Query: 1006 LEGSPQSQCQSDHQWNPPLAVC 1027
L G CQ ++QW+ + +C
Sbjct: 656 LIGEKSIVCQENNQWSANIPIC 677
Score = 41.2 bits (95), Expect = 0.005
Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 33/256 (12%)
Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
CP P NG GS DF G+TV ++C+ ++ L G +I C + W
Sbjct: 446 CPDPGEPENGKRIGS---DFSLGSTVQFSCDE------DYVLQGAKSITCQRIAEVFAAW 496
Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
S P+CK+ S++ +G + P+ Y+ +C T ++++
Sbjct: 497 SDHRPVCKVKTCG---SNLQGPSG-TFTSPNFPFQYDSNA--QCVWVITAVNTNKVIQIN 550
Query: 647 DNTWDPEI-----PVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKS 701
+D EI + + G P TG FV + V + L ++S
Sbjct: 551 FEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGS----FVPDLIVSMSSQMWLHLQTDES 606
Query: 702 IHCMPSGNWSPSAPRCE-ETCQHVRQSLQELPAG---SRVELVNTSCQDGYQLTGHAYQM 757
+ S + + E E+C L + G S +++ CQ G++L G +
Sbjct: 607 V---GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIV 663
Query: 758 CQDAENGIWFKKIPLC 773
CQ EN W IP+C
Sbjct: 664 CQ--ENNQWSANIPIC 677
Score = 40.4 bits (93), Expect = 0.009
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 9/71 (12%)
Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
CP P NG+ IG+ S GS V ++CD D ++L G ++ C ++ W
Sbjct: 446 CPDPGEPENGKRIGSDF---SLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAW 496
Query: 336 SGPAPRCELST 346
S P C++ T
Sbjct: 497 SDHRPVCKVKT 507
Score = 40.4 bits (93), Expect = 0.009
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P P NG + VG I + C + LIG +L C+ V W+ P P+
Sbjct: 2183 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCL--HGVSRNWNHPLPR 2238
Query: 82 CE 83
CE
Sbjct: 2239 CE 2240
Score = 38.9 bits (89), Expect = 0.027
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 1660 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
Query: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
C P G + G S Y SV C + ++ V+ Q
Sbjct: 1718 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1764
Query: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 1765 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1823
Query: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 1824 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1874
Query: 253 SSRCVIAGQGVA-WT-KMPVC 271
+ RC +A W +P C
Sbjct: 1875 AIRCETVPNSLAQWNDSLPTC 1895
Score = 37.7 bits (86), Expect = 0.060
Identities = 74/300 (24%), Positives = 108/300 (36%), Gaps = 61/300 (20%)
Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCE 272
C G NGK + +G T F CDE Y LQG S C IA AW+ PVC+
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 273 EIFCPSPPPILNGRHIGNSL-----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTL 323
C S +G + +N ++T + + +NF + IG TL
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTL 563
Query: 324 RCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVI 376
D + G PR L Q+L G V S Q + D +
Sbjct: 564 TIG-DGGEVGD-----PRTVL----------QVLTGSFVPDLIVSMSSQMWLHLQTDESV 607
Query: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
+ F K ++ C GT P + E + +R ++RF+
Sbjct: 608 GSVGFKVNYKEIEKESCGDPGT--PLYGIREGD----------GFSNRDVLRFE------ 649
Query: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
C G+ L+GE+SI C W+ +P C + C + T P + PD G
Sbjct: 650 --CQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 702
Score = 36.6 bits (83), Expect = 0.13
Identities = 65/272 (23%), Positives = 97/272 (35%), Gaps = 55/272 (20%)
Query: 344 LSTSAVQCPHPQILRGRMVSGQK--DRYTYNDTVIFACMFGFTLKGSKQIRC----NAQG 397
+ T++ CP P G +G++ ++ TV F+C + L+G+K I C
Sbjct: 439 IKTASNLCPDP----GEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 494
Query: 398 TWEPSAPVCE-KEC----QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-----G 447
W PVC+ K C Q P P +Y N V V
Sbjct: 495 AWSDHRPVCKVKTCGSNLQGPSGTFT-----------SPNFPFQYDSNAQCVWVITAVNT 543
Query: 448 EESIQCTSE------GVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKL 501
+ IQ E G T + T Q+LT FV PD+ S L
Sbjct: 544 NKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLT---GSFV-PDLIVSMSSQMWL 599
Query: 502 SGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
E G++ + + + ++ +C P G G + F + + C G
Sbjct: 600 HLQT-DESVGSVGFKVNYKEIEKESCGDPGTPLYGIREG---DGFSNRDVLRFECQFG-- 653
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
F LIGE +I C N+Q WS P+C
Sbjct: 654 ----FELIGEKSIVCQENNQ----WSANIPIC 677
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 965
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 138 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
Query: 966 CK 967
C+
Sbjct: 195 CR 196
Score = 35.8 bits (81), Expect = 0.23
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 986 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 1028
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 154 CPALPMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPP 208
CP NG + +GS + G +V +SC+ Y+L G K I C + WS P
Sbjct: 446 CPDPGEPENG----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 501
Query: 209 TCEEARCKSLGRFPNGKVKEP 229
C+ C S + P+G P
Sbjct: 502 VCKVKTCGSNLQGPSGTFTSP 522
Score = 34.7 bits (78), Expect = 0.51
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 838
F G+++ Y C G+ L G +L C ++S SW P P C
Sbjct: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 1022
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 131 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 190
Query: 1023 PLAVCRS 1029
P+ +CR+
Sbjct: 191 PVPICRA 197
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137
SSC P VP + G T + GD + ++C T + ++G+ + C AN++
Sbjct: 136 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 183
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
CP+P P K GS + G +V F+C ++ + G KS+ CQ
Sbjct: 446 CPDPGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQ 487
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 14/73 (19%)
Query: 522 CKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQ 581
C PP V+Y F G + Y+C G + L G + C +N
Sbjct: 138 CGNPGVPPKGVLYGTR--------FDVGDKIRYSCVTG------YILDGHPQLTCIANSV 183
Query: 582 ERGTWSGPAPLCK 594
+W P P+C+
Sbjct: 184 NTASWDFPVPICR 196
Score = 31.2 bits (69), Expect = 5.6
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 176 GLSVTYSCESGYLLVGEKIINCL----SSGKWSAVPPTCE-EARCKSLGRFPNGKVKEP 229
G + YSC +GY+L G + C+ ++ W P C E C R +G + P
Sbjct: 157 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSP 215
Score = 31.2 bits (69), Expect = 5.6
Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C P NG+ + ++G+ +++SC + L G KS+ C +V W P C
Sbjct: 446 CPDPGEPENGK--RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
Query: 83 E 83
+
Sbjct: 504 K 504
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 353 bits (905), Expect = 6e-97
Identities = 288/975 (29%), Positives = 421/975 (43%), Gaps = 106/975 (10%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C +P +G I T + +V+R++C FRL+G+ S +C WD P P C
Sbjct: 2569 CSTPESPPHGYI-ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2627
Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK--SVWCQANNMW-G 139
+ SC P P I +T Y G VT+ C + ++ + + CQ++ W
Sbjct: 2628 QAI----SCGIPKAPTNGGIL-TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSN 2682
Query: 140 PTRLPTCVSVFPLECPALP--MIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINC 197
+ P CV V CP++ ++ +G N V +SC+ GY +G I C
Sbjct: 2683 HNKTPRCVVV---TCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIEC 2739
Query: 198 LSSGKWS--AVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
L +G WS P C+ C L PNG K G TA F CD G+ L G
Sbjct: 2740 LPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2798
Query: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C+ +G W++ C C P I+NG+ IG N Y V Y C+P
Sbjct: 2799 CLSSG---LWSESETRCLAGHCGIPELIVNGQVIGE---NYGYRDTVVYQCNP------G 2846
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQK--DRYTYN 372
F LIG S C Q+ WSG P C V C HP G + G+ + + +N
Sbjct: 2847 FRLIGSSVRIC----QQDHNWSGQLPSC----VPVSCGHP----GSPIYGRTSGNGFNFN 2894
Query: 373 DTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDR-HMVRFD 430
D V F+C G+ ++G + +C A W P+C+ C P N ++E + F
Sbjct: 2895 DVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT 2954
Query: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG---RQLLTKPQHQFV 487
GT + Y CNPGY L G + C G W P+P+C + C G +L+ ++ F
Sbjct: 2955 YGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTF- 3013
Query: 488 RPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCK---EITCPPPPVIYNGAHTGSSLE 544
V+ SC L G + CQ W C TC P +G+ S
Sbjct: 3014 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQES--- 3070
Query: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
+F +TV Y C+ G + L G C +N G+W+G P CK AVQC +
Sbjct: 3071 NFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECK----AVQCGN 3116
Query: 605 V-HIANG--YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC 661
ANG ++I G ++ +V + C G+ L G S +C A+ TW +P C
Sbjct: 3117 PGTTANGKVFRIDGTT----FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIIS 3172
Query: 662 QSPPGL-HHGRHTGGNTVFFVSGMTVDYTCDPGYL--LVGNKSIHCMPSGNWSPSAPRCE 718
PG+ +G G + +V G V Y C PGY L G++ C +G WS P C
Sbjct: 3173 CGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCR 3229
Query: 719 E-TCQHVRQSLQELPAGSRVE---LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
TC Q G+ + ++ C GY+L+ A C NG W ++P C
Sbjct: 3230 AVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTC--VGNGTWSGEVPQCL 3287
Query: 775 VIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
C P + GK G ++F+Y +EVS+ C+ F L+G C++D G+WSG
Sbjct: 3288 PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQAD----GTWSGS 3340
Query: 835 SPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN 893
SP C+ P T C NP V +HG + N + +V C G ++ GS C D
Sbjct: 3341 SPHCI-EPTQTSCENPGVPRHGSQNNT--FGFQVGSVVQFHCKKGHLLQGSTTRTCLPDL 3397
Query: 894 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEALLL 952
TW P CI + C P + N G ++ S G +++Y+C G+ L G +
Sbjct: 3398 TWSGIQPECIPHS---CKQPETPAHANVVGMDLP--SHGYTLIYTCQPGFFLAGGTEHRV 3452
Query: 953 CTHEGTWSQPAPHCK 967
C + TW+ P C+
Sbjct: 3453 CRSDNTWTGKVPICE 3467
Score = 335 bits (860), Expect = 1e-91
Identities = 286/1071 (26%), Positives = 438/1071 (40%), Gaps = 137/1071 (12%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C PPP+ N I +G +IRY C F L+G L C +++ D P C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ--MDGAPPVC 2452
Query: 83 E--------------------YFNKYSS---CPEPI-VPGGYKI---------------- 102
+ Y + Y + C I V GY I
Sbjct: 2453 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2512
Query: 103 ------RGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
+P S ++ N + NG++ V+ Q + G + + C
Sbjct: 2513 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHE-VFLQWSADHGNNKKGFRIRYIAFYCST 2571
Query: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG----KWSAVPPTCEE 212
+G+ S+ G + V ++C+ G+ LVG+ C S W A P C+
Sbjct: 2572 PESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2629
Query: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT---KMP 269
C NG + L VG +FC++GYRL + V G W+ K P
Sbjct: 2630 ISCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDG-TWSNHNKTP 2687
Query: 270 VCEEIFCPSPPPIL--NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV 327
C + CPS + +GR + ++ Y + V ++CDP + +G +++ C
Sbjct: 2688 RCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDP------GYHGLGPASIECLP 2741
Query: 328 DSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
+ T +W P C++ S + P P G + Q +Y T IF C GF L G
Sbjct: 2742 NG--TWSWRNERPYCQI-ISCGELPTPP--NGNKIGTQT---SYGSTAIFTCDLGFMLVG 2793
Query: 388 SKQIRCNAQGTWEPSAPVC-EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV 446
S C + G W S C C P I+NGQ + D ++ Y CNPG+ L+
Sbjct: 2794 SAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRD---TVVYQCNPGFRLI 2850
Query: 447 GEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQ-HQFVRPD-VNSSCGEGYKLSGS 504
G C + W+ +P C +C G + + + F D V SC GY + G
Sbjct: 2851 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGP 2910
Query: 505 VYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE--DFPYGTTVTYTCNPGPER 562
+CQ W +CK + C P + N S +E +F YGT V Y CNPG
Sbjct: 2911 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE-SKIEHGNFTYGTVVFYDCNPG--- 2966
Query: 563 GVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFY 622
+ L G S + C Q G W P P C + + C H + +SG++ Y +
Sbjct: 2967 ---YFLFGSSVLIC----QPNGQWDKPLPEC----IMIDCGHPGVPPNAVLSGEK--YTF 3013
Query: 623 NDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG----CQSPPGLHHGRHTGGNTV 678
TV + C +L G S C+ + W P C C P HG N
Sbjct: 3014 GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-- 3071
Query: 679 FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQH----VRQSLQELPA 733
F + TV Y CD GY+L G++ C+ +G+W+ P C+ C + + +
Sbjct: 3072 -FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3130
Query: 734 GSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMM 793
+ V SC +GY L+G + + C NG W +P C +I C P + NG G
Sbjct: 3131 TTFSSSVIYSCMEGYILSGPSVRQC--TANGTWSGTLPNCTIISCGDPGIPANGLRYG-- 3186
Query: 794 AENFLYGNEVSYECDQGF--YLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE 851
++++ G VSY C G+ L G + C +G+WSG P C CP P
Sbjct: 3187 -DDYVVGQNVSYMCQPGYTMELNGSRIRTCTI----NGTWSGVMPTC----RAVTCPTPP 3237
Query: 852 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
+L T+ + + I Y+ C+PG+ ++ V+ C + TW VP C+ K F G P
Sbjct: 3238 QISNGRLEGTNFDWGFS-ISYI-CSPGYELSFPAVLTCVGNGTWSGEVPQCLPK-FCGDP 3294
Query: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
P G G + F + +SC+ ++LVG + +C +GTWS +PHC E
Sbjct: 3295 GIP--AQGKREGKS---FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3349
Query: 972 SSPADMDGIQKGLEPRKM-YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
+S + + G + +Q G+VV C+ G++L+GS C D W+
Sbjct: 3350 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWS 3400
Score = 328 bits (840), Expect = 2e-89
Identities = 280/988 (28%), Positives = 400/988 (40%), Gaps = 105/988 (10%)
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
+K + Y Y S PE P GY I T + V +AC F + G S C+ +
Sbjct: 2556 NKKGFRIRYIAFYCSTPES-PPHGYII-SQTGGQLNSVVRWACDRGFRLVGKSSAVCRKS 2613
Query: 136 NM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
+ W +P C ++ P P + G T++ + G VTY C GY L
Sbjct: 2614 SYGYHAWDAP-VPACQAI-SCGIPKAPT-NGGILTTDYL----VGTRVTYFCNDGYRLSS 2666
Query: 192 EKIIN--CLSSGKWSA--VPPTCEEARCKSLGRF----PNGKVKEPPILRVGVTANFFCD 243
+++ C S G WS P C C S+ F ++ F CD
Sbjct: 2667 KELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCD 2726
Query: 244 EGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
GY GP S C+ G + P C+ I C P NG IG SYGS +
Sbjct: 2727 PGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQ---TSYGSTAIF 2783
Query: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVS 363
TCD + F+L+G + C +G WS RC A C P+++ V
Sbjct: 2784 TCD------LGFMLVGSAVRECL----SSGLWSESETRC----LAGHCGIPELIVNGQVI 2829
Query: 364 GQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKE 422
G+ Y Y DTV++ C GF L GS C W P C C P + + G+
Sbjct: 2830 GEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS 2887
Query: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKP 482
F+ + +SCN GY++ G QC + W+ P P CKV C G +K
Sbjct: 2888 GNG---FNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKR 2944
Query: 483 QHQFVRPD------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
+ + + V C GY L GS CQ W + C I C P V N
Sbjct: 2945 ESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA 3004
Query: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
+G E + +G+TV Y+C + SL+G+S+ C N G WSG P C
Sbjct: 3005 VLSG---EKYTFGSTVHYSCTG------KRSLLGQSSRTCQLN----GHWSGSQPHCSGD 3051
Query: 597 LLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV 656
+G S +E+ + TV + C +G+ L GS + C A+ +W P
Sbjct: 3052 ATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPE 3108
Query: 657 CEKGCQSPPGLHHGRHTGGNTVFFVSGMT----VDYTCDPGYLLVGNKSIHCMPSGNWSP 712
C+ PG T VF + G T V Y+C GY+L G C +G WS
Sbjct: 3109 CKAVQCGNPGT-----TANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSG 3163
Query: 713 SAPRCEE-TCQHVRQSLQELPAGSRVEL---VNTSCQDGY--QLTGHAYQMCQDAENGIW 766
+ P C +C L G + V+ CQ GY +L G + C NG W
Sbjct: 3164 TLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTC--TINGTW 3221
Query: 767 FKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK 826
+P C+ + C PP I NG+ G NF +G +SY C G+ L L C
Sbjct: 3222 SGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPGYELSFPAVLTC----V 3274
Query: 827 GHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV 886
G+G+WSG PQCL C +P + K + ++ + V CN FI+ GS
Sbjct: 3275 GNGTWSGEVPQCLPK----FCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFILVGSST 3328
Query: 887 IRCHTDNTWVPGVPTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
C D TW P CI+ C P P+ + N+T G F G + + C +G+L
Sbjct: 3329 RICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFG----FQVGSVVQFHCKKGHL 3384
Query: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGY 1004
L G C + TWS P C +C P + + +G + C+ G+
Sbjct: 3385 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGF 3442
Query: 1005 MLEGSPQSQ-CQSDHQWNPPLAVCRSRS 1031
L G + + C+SD+ W + +C + S
Sbjct: 3443 FLAGGTEHRVCRSDNTWTGKVPICEAGS 3470
Score = 281 bits (718), Expect = 3e-75
Identities = 235/798 (29%), Positives = 342/798 (42%), Gaps = 107/798 (13%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
ISCG P NG + T + G+ ++C F L+G C++ G W +
Sbjct: 2757 ISCGELPTPPNG--NKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS----GLWSESET 2810
Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
+C + PE IV G ++ G Y + D+V + C F + G+ CQ ++ W
Sbjct: 2811 RC--LAGHCGIPELIVNG--QVIGEN-YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSG 2865
Query: 141 TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 198
+LP+CV P+ C P P+ N + VT+SC GYL+ G C
Sbjct: 2866 -QLPSCV---PVSCGHPGSPIYGRTSGNGFNFNDV-----VTFSCNIGYLMQGPTKAQCQ 2916
Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVK---EPPILRVGVTANFFCDEGYRLQGPPSSR 255
++ +WS PP C+ C G N K + E G + C+ GY L G
Sbjct: 2917 ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2976
Query: 256 CVIAGQGVAWTK-MPVCEEIFC--PSPPP--ILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
C GQ W K +P C I C P PP +L+G ++GS V Y+C
Sbjct: 2977 CQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGE-------KYTFGSTVHYSCTGKRS 3026
Query: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
L+G+S+ C Q G WSG P C + C P S Q+ +
Sbjct: 3027 ------LLGQSSRTC----QLNGHWSGSQPHCSGDATGT-CGDPG--TPGHGSRQESNFR 3073
Query: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRF 429
TV +AC G+ L GS++ C A G+W P C+ +C P NG+ + R
Sbjct: 3074 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGK-----VFRI 3128
Query: 430 DPGT---SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG--RQLLTKPQH 484
D T S+ YSC GY+L G QCT+ G W+ +P C + +C G L
Sbjct: 3129 DGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD 3188
Query: 485 QFVRPDVNSSCGEGY--KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
V +V+ C GY +L+GS + C W + C+ +TCP PP I NG G+
Sbjct: 3189 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT- 3247
Query: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
+F +G +++Y C+PG + L + + C N GTWSG P C L C
Sbjct: 3248 --NFDWGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQC----LPKFC 3291
Query: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC----E 658
I K GK + Y V+F C F L GSS C+AD TW P C +
Sbjct: 3292 GDPGIPAQGKREGKS--FIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3349
Query: 659 KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC- 717
C++P HG + NT F G V + C G+LL G+ + C+P WS P C
Sbjct: 3350 TSCENPGVPRHG--SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECI 3407
Query: 718 ------EETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWFKKI 770
ET H +LP+ + +CQ G+ L G +++C+ + W K+
Sbjct: 3408 PHSCKQPETPAHANVVGMDLPSHGYTLIY--TCQPGFFLAGGTEHRVCR--SDNTWTGKV 3463
Query: 771 PLC----KVIHCHPPPVI 784
P+C K++ P P +
Sbjct: 3464 PICEAGSKILVKDPRPAL 3481
Score = 225 bits (573), Expect = 2e-58
Identities = 188/661 (28%), Positives = 270/661 (40%), Gaps = 75/661 (11%)
Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
P + +SCG P + GR S V+ +SC+ + + G C + + W
Sbjct: 2868 PSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQC----QANRQW 2921
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWC 132
P P C+ N C +P +P K + +G V + C + + G+ + C
Sbjct: 2922 SHPPPMCKVVN----CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2977
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Q N W LP C+ + +C + N + E G +V YSC L+G+
Sbjct: 2978 QPNGQWDKP-LPECIMI---DCGHPGVPPNAVLSGE---KYTFGSTVHYSCTGKRSLLGQ 3030
Query: 193 KIINCLSSGKWSAVPPTCE---EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
C +G WS P C C G +G +E R T + CD GY L
Sbjct: 3031 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH 3089
Query: 250 GPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
G C+ G +WT + P C+ + C +P NG+ + ++ S V Y+C
Sbjct: 3090 GSEERTCLANG---SWTGRQPECKAVQCGNPGTTANGKVF--RIDGTTFSSSVIYSC--- 3141
Query: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368
EG +IL G S +CT + GTWSG P C + + C P I + G D
Sbjct: 3142 -MEG--YILSGPSVRQCTAN----GTWSGTLPNCTI----ISCGDPGIPANGLRYG--DD 3188
Query: 369 YTYNDTVIFACMFGFT--LKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRH 425
Y V + C G+T L GS+ C GTW P C C PP I NG+ E
Sbjct: 3189 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG-- 3246
Query: 426 MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
FD G SI Y C+PGY L + C G W+ VPQC C G K + +
Sbjct: 3247 -TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGK 3305
Query: 486 --FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTG 540
+ +V+ SC + L GS + CQ W C E T C P V +G+
Sbjct: 3306 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3365
Query: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
+ F G+ V + C G L+ ST R D TWSG P C +
Sbjct: 3366 TF--GFQVGSVVQFHCKKG-------HLLQGSTTRTCLPDL---TWSGIQPEC----IPH 3409
Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADNTWDPEIPVCEK 659
C + G + P + T+ + C GF L G ++ R C++DNTW ++P+CE
Sbjct: 3410 SCKQPETPAHANVVGMDLP-SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3468
Query: 660 G 660
G
Sbjct: 3469 G 3469
Score = 206 bits (525), Expect = 7e-53
Identities = 158/570 (27%), Positives = 242/570 (42%), Gaps = 68/570 (11%)
Query: 491 VNSSCGEGYKLSGSVYQECQ----GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
V +C G++L G C+ G W + C+ I+C P NG G D+
Sbjct: 2592 VRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNG---GILTTDY 2648
Query: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG--PAPLCKLSLLAVQCSH 604
GT VTY CN G S +T C S+ GTWS P C + V C
Sbjct: 2649 LVGTRVTYFCNDG----YRLSSKELTTAVCQSD----GTWSNHNKTPRC----VVVTCPS 2696
Query: 605 VH---IANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD--PEIPVCEK 659
++ + +G + Y Y V F C G+ G + I C + TW E P C+
Sbjct: 2697 INSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQI 2756
Query: 660 -GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE 718
C P +G G T + G T +TCD G++LVG+ C+ SG WS S RC
Sbjct: 2757 ISCGELPTPPNGNKIGTQTSY---GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC- 2812
Query: 719 ETCQHVRQSLQELPAGSRV--------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKI 770
H + EL +V + V C G++L G + ++CQ N W ++
Sbjct: 2813 -LAGHC--GIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQL 2867
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
P C + C P + G+ +G F + + V++ C+ G+ + G K QC+++ +
Sbjct: 2868 PSCVPVSCGHPGSPIYGRTSG---NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ---- 2920
Query: 831 WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIR 888
WS P P C V C +P + K H +++ +V+ DCNPG+ + GS V+
Sbjct: 2921 WSHPPPMC----KVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLI 2976
Query: 889 CHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 948
C + W +P CI I C P PN +G +++ G ++ YSC L+G+
Sbjct: 2977 CQPNGQWDKPLPECI---MIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQ 3030
Query: 949 ALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEG 1008
+ C G WS PHC + D G ++ + V C+ GY+L G
Sbjct: 3031 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHG 3090
Query: 1009 SPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
S + C ++ W C++ V CG
Sbjct: 3091 SEERTCLANGSWTGRQPECKA-----VQCG 3115
Score = 99.0 bits (245), Expect = 2e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 3224 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3277
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 3278 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3332
Query: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 3333 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3387
Query: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 3388 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3447
Query: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
R + WT K+P+CE +I P P L
Sbjct: 3448 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3481
Score = 82.0 bits (201), Expect = 3e-15
Identities = 214/1039 (20%), Positives = 328/1039 (31%), Gaps = 272/1039 (26%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKVKEPPI 231
G +VTY C++GY+L G + C+ W+ P+C A C S G V P
Sbjct: 1720 GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH-APCGSRSTGSEGTVLSP-- 1776
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFC-----PSPPPILNG 285
N+ V+ GQ V + T + E++ S L+G
Sbjct: 1777 ---NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1833
Query: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
H G SL S I P F + ++ R
Sbjct: 1834 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR--------------------- 1872
Query: 346 TSAVQC---PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGT 398
TS+ QC P P+ GR + + + +V+F C G+ L GS IRC N+
Sbjct: 1873 TSSTQCSSVPEPRF--GRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1927
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W S P C C IL +K GT + +PGY + ++ C V
Sbjct: 1928 WNDSLPTCIVPCGG---ILTKRK----------GTIL----SPGYPEPYDNNLNC----V 1966
Query: 459 WTPPVP-------QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-----KLSGSVY 506
W VP Q A E L P + S G S ++Y
Sbjct: 1967 WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLY 2026
Query: 507 QECQGTIP-----WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Q I + +E +CP P +G G + + G V++ C+ G
Sbjct: 2027 LNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCDQG-- 2081
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK---ISGKEA 618
+SL G S I C R + P L + S V ++ G+ S +
Sbjct: 2082 ----YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDC 2137
Query: 619 PYFYNDTVTFKCYSGFT-------------LKGSSQIRCKADNTWDPEIPVCE------- 658
+ N + F + F GSS+ P+IP
Sbjct: 2138 TWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHET 2197
Query: 659 ------------------------KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY 694
+ C P +G G + F G T+ + C PGY
Sbjct: 2198 SLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND---FTVGQTISFECFPGY 2254
Query: 695 LLVGNKSIHCM--PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 752
L+GN ++ C+ S NW+ PRCE C G+ + T GY
Sbjct: 2255 TLIGNSALTCLHGVSRNWNHPLPRCEALC-----------GGNITAMNGTIYSPGYPDEY 2303
Query: 753 HAYQMCQDAENGIWFKKIP-------LCKVIHCHPPPVIVN------------GKHTGMM 793
+Q C W ++P V+ P + G+ +G
Sbjct: 2304 PNFQDC------FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNT 2357
Query: 794 AENFLYGNE----VSYECD---QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTR 846
A +Y + + D GF++L Q R C PPV
Sbjct: 2358 ALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR--------------VCQPPPPV-- 2401
Query: 847 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT-DNTWVPGVPTCIKK 905
PN E+ + DI+ C PGF + G+ ++ C + + G P +
Sbjct: 2402 -PNAEIL------TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ- 2453
Query: 906 AFIGCPP----------------PPKTPN--------GNHTGGNIARFSPGMSILYSCDQ 941
+ CP P PN G NI F D
Sbjct: 2454 --VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDV 2511
Query: 942 GYLLVG---EALLLCTHEGTWSQP---APHCKEVNCSSPADMDGIQKGLEPRKMYQY--- 992
+ G ++ +L + G +S + EV AD +KG R + Y
Sbjct: 2512 LQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCST 2571
Query: 993 -----------------GAVVTLECEDGYMLEGSPQSQCQSD----HQWNPPLAVCRSRS 1031
+VV C+ G+ L G + C+ H W+ P+ C++ S
Sbjct: 2572 PESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS 2631
Query: 1032 LAPVLCGIAAGLILLTFLI 1050
G++ +L+
Sbjct: 2632 CGIPKAPTNGGILTTDYLV 2650
Score = 80.5 bits (197), Expect = 8e-15
Identities = 156/664 (23%), Positives = 237/664 (35%), Gaps = 164/664 (24%)
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEATGRQ---LLTKPQ 483
F G ++ +SC+ GY L G I C G VW+ P+P+C VA C A+ +L P
Sbjct: 1198 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPN 1256
Query: 484 HQFVRPDVNSSC--------GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
+ + + N C G+G +S + QG + ++I K+ T
Sbjct: 1257 YP-LNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---LKIYDGKDKTTH-----LL 1307
Query: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
GA TG+S+ G T++ T N + +EF N GT G L
Sbjct: 1308 GAFTGASMR----GLTLSSTSN---QLWLEF------------NSDTEGTDEG-FQLVYT 1347
Query: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD--NTWDP 652
S C I GYKIS + +F T+ + C G+TL GSS ++C WD
Sbjct: 1348 SFELSHCEDPGIPQFGYKIS--DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1405
Query: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM-----PS 707
+P C C GR G ++ +S PGY + ++ CM
Sbjct: 1406 PLPSCIAEC-------GGRFKGESSGRILS---------PGYPFPYDNNLRCMWMIEVDP 1449
Query: 708 GN--------------------WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDG 747
GN W P + + + SL S + +V
Sbjct: 1450 GNIVSLQFLAFDTEASHDILRVWD-GPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTD 1508
Query: 748 YQL--TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 805
+ + +G A Q C P V +NG G E G+ V +
Sbjct: 1509 FYISKSGFAIQFSSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVF 1552
Query: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH 862
+CD G+ L GE+++ C + W SPPV P N G+ L+
Sbjct: 1553 QCDPGYELQGEERITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNF 1604
Query: 863 -SAYSHNDIVYVDCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPP 912
Y H+ DC+ +N VI + D ++ P IG
Sbjct: 1605 PHPYPHSR----DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQ 1659
Query: 913 PPKTPNGNHTGGNIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
K P + N F S+ Y+ G+ L +A L +
Sbjct: 1660 DSKLPERIESSSNTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RES 1700
Query: 971 CSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLA 1025
C P + M+G + G++ Y+ G+ VT C+ GY+L+G C WN L
Sbjct: 1701 CFDPGNIMNGTRLGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1756
Query: 1026 VCRS 1029
C +
Sbjct: 1757 SCHA 1760
Score = 72.4 bits (176), Expect = 2e-12
Identities = 138/646 (21%), Positives = 228/646 (35%), Gaps = 124/646 (19%)
Query: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 1718 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1776
Query: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 1777 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1832
Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
+ L + SG + T+ F + T KG + ++ +
Sbjct: 1833 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1877
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 1878 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1934
Query: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
C + C +LTK + + P Y E P+ + +I
Sbjct: 1935 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1969
Query: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
T P V + H SL+ + G N P G + TSN
Sbjct: 1970 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 2023
Query: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 2024 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 2080
Query: 633 GFTLKGSSQIRCKAD--NTWDPEIPVCEKGCQS----------PPGLHHGRHTGGNTVFF 680
G++L+G S I C W+ IP+C C PG G + +
Sbjct: 2081 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGF-PGNYPSSLDCTW 2139
Query: 681 VSGMTVDYTCDPGYLLVGNKSIHC---MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
+ + + ++ ++IH + SG+ S + + SL + +
Sbjct: 2140 TINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSL 2199
Query: 738 ELVNTSCQD--GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
+ Q+ G+ + AYQ+ C P NG ++
Sbjct: 2200 YFHSDYSQNKQGFHIVYQAYQLQS------------------CPDPRPFRNG---FVIGN 2238
Query: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPSPQC 838
+F G +S+EC G+ L+G L C HG +W+ P P+C
Sbjct: 2239 DFTVGQTISFECFPGYTLIGNSALTCL-----HGVSRNWNHPLPRC 2279
Score = 62.4 bits (150), Expect = 2e-09
Identities = 145/624 (23%), Positives = 214/624 (34%), Gaps = 142/624 (22%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 1029 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 1081
Query: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
GY P S C V G+GV + + + E P
Sbjct: 1082 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1132
Query: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 1133 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1192
Query: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
NF + T C+ + GT WS P PRC A + IL
Sbjct: 1193 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1252
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Y N C++ ++ K I +A+ V + I
Sbjct: 1253 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1297
Query: 418 NGQKEDRHMVRFDPGTSIK----YSCNPGYVLVGEESIQCTSEG---VWTP-PVPQCKVA 469
+G+ + H++ G S++ S + L + T EG V+T + C+
Sbjct: 1298 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1357
Query: 470 ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ--GTIPWFMEIRLCKEITC 527
G ++ Q F + C GY L GS +C W + C C
Sbjct: 1358 GIPQFGYKI--SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAEC 1414
Query: 528 PPPPVIYNGAHTGSSLE---DFPYGTTV----TYTCNPGPERGVEFSLIGESTIRCTSND 580
+ G +G L FPY + +PG ++F S+D
Sbjct: 1415 GGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1467
Query: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640
R W GP + +L + S I G S DT + SGF ++ SS
Sbjct: 1468 ILR-VWDGPP---ENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS 1522
Query: 641 QIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
+ A DP +P+ +G G G TV + CDPGY L G +
Sbjct: 1523 SV---ATACRDPGVPM------------NGTRNGDGR---EPGDTVVFQCDPGYELQGEE 1564
Query: 701 SIHCMPSGN---WSPSAPRCEETC 721
I C+ N W PS P C C
Sbjct: 1565 RITCIQVENRYFWQPSPPVCIAPC 1588
Score = 58.9 bits (141), Expect = 3e-08
Identities = 134/619 (21%), Positives = 214/619 (34%), Gaps = 128/619 (20%)
Query: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 1200 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1257
Query: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Y N + V G I S H GD + T SM G
Sbjct: 1258 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1317
Query: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 1318 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1373
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 1374 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1419
Query: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 1420 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1476
Query: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 1477 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1521
Query: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 1522 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1578
Query: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
PS PVC C +G H + N YV+ S+ S
Sbjct: 1579 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1634
Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
+ P + + L+ Q + + SS ++ GSV
Sbjct: 1635 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1688
Query: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 1689 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1739
Query: 575 RCTSNDQERGTWSGPAPLC 593
C D R W+ P C
Sbjct: 1740 TCIMGDDGRPGWNRALPSC 1758
Score = 57.8 bits (138), Expect = 6e-08
Identities = 109/481 (22%), Positives = 163/481 (33%), Gaps = 115/481 (23%)
Query: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 1181 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1235
Query: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
C A C + G + P Y L + C+ + Q A
Sbjct: 1236 RC-VAECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAG--- 1276
Query: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
G +I +++ G ++ D + G S T+
Sbjct: 1277 ---------------KGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1321
Query: 329 SQKTGTW-------SGPAPRCELSTSAVQCPH------PQILRGRMVSGQKDRYTYNDTV 375
S W G +L ++ + H PQ G +S Q + T+
Sbjct: 1322 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ--GHFAGSTI 1377
Query: 376 IFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
I+ C G+TL GS ++C + W+ P C EC RF G
Sbjct: 1378 IYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RF-KGE 1421
Query: 434 SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----P 489
S +PGY + +++C +W V + + + T+ H +R P
Sbjct: 1422 SSGRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGP 1475
Query: 490 DVNSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPV 532
N + ++SGS+ E TI + + + K C P V
Sbjct: 1476 PENDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGV 1533
Query: 533 IYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPL 592
NG G E G TV + C+PG + L GE I C + R W P+
Sbjct: 1534 PMNGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCI-QVENRYFWQPSPPV 1583
Query: 593 C 593
C
Sbjct: 1584 C 1584
Score = 54.3 bits (129), Expect = 6e-07
Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 48/286 (16%)
Query: 631 YSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
Y+GF L+ +++R + C P + +G G + + G TV Y C
Sbjct: 1686 YTGFHLEYKAKLR---------------ESCFDPGNIMNGTRLGMD---YKLGSTVTYYC 1727
Query: 691 DPGYLLVGNKSIHCMPSGN----WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
D GY+L G ++ C+ + W+ + P C C GS +++ +
Sbjct: 1728 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC-------GSRSTGSEGTVLSPNYPK 1780
Query: 747 GYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 804
Y + GH Y + E ++ + + +H V + G ++ L +
Sbjct: 1781 NYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH------DVVEVYDGPTQQSSLLSSLSG 1833
Query: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQCLRSPPVTRCPN-PEVKHGYKLNKT 861
+ L ++ R S G + G Q + T+C + PE + G ++
Sbjct: 1834 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG-- 1891
Query: 862 HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGVPTCI 903
+ ++ V DCNPG+I++GS IRC T W +PTCI
Sbjct: 1892 -NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1936
Score = 51.2 bits (121), Expect = 5e-06
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 59/252 (23%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P + V+G+ G +F G+ VS+ CD G+ L E+ L C K H WS P P
Sbjct: 1010 CLDPGIPVHGRRYG---HDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHW-WSHPLPT 1062
Query: 838 C-------LRSPPVTRC--------PNP-------EVKHGYKLN---KTHSAYSHNDIVY 872
C +R P T PN +V HG + T H+D +
Sbjct: 1063 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1122
Query: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA--FIG--------------------C 910
+ N F +R+ T G+ + FI C
Sbjct: 1123 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1182
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHCKE 968
P G+ G N F G ++ +SC GY L G + ++C G WS P P C
Sbjct: 1183 EDPGIPQYGSRIGFN---FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1239
Query: 969 VNCSSPADMDGI 980
+S + +GI
Sbjct: 1240 ECGASATNNEGI 1251
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/414 (21%), Positives = 146/414 (35%), Gaps = 88/414 (21%)
Query: 616 KEAPYFYN-DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV----CEKGCQSPPGL--- 667
+E F N D + F+C GF L G I C+ +N W IP+ C +P G
Sbjct: 675 REGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLS 734
Query: 668 -HHGRHTGGN-----TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
+ G N T+ G + + + + L + G+ SP +P T
Sbjct: 735 PDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFT 792
Query: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
V L S ++ Q + ++G + + + C
Sbjct: 793 GAEVPSHLT-----SNSHILRLEFQADHSMSGRGFNITYNTFGHN-----------ECPD 836
Query: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCL 839
P + +N + G +NF G+ +S C++GF G + + C G WSG P+C
Sbjct: 837 PGIPINARRFG---DNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCG 892
Query: 840 R------SPPVTRCPNP----------------EVKHGYKLNKTHSAYS---HNDIVYVD 874
S P +P E + G+ + T + + D++ V
Sbjct: 893 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 952
Query: 875 CNPGFIM------NGSRV------------IRCHTDNTWVP-GVPTCIKKAFIG---CPP 912
P + NG++V + TDN+ G + + C
Sbjct: 953 DGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLD 1012
Query: 913 PPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
P +G G + FS G ++ +SCD GY L E LLC WS P P C
Sbjct: 1013 PGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 1063
Score = 45.8 bits (107), Expect = 2e-04
Identities = 221/1045 (21%), Positives = 335/1045 (32%), Gaps = 223/1045 (21%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG P L G + V+R+ C F LIGEKS++C + + W P
Sbjct: 663 SCGDPGTPLYGIRE--GDGFSNRDVLRFECQFGFELIGEKSIVC----QENNQWSANIPI 716
Query: 82 C------EYFNKYSSCPEPIVPGGYK---------IRGSTPYRHGDSVTFACKTNFSMNG 126
C + + P P GY I H F ++ F
Sbjct: 717 CIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLA 776
Query: 127 NKSVWCQANNMWG-------PTRLPTCVSVFPLECPA--------LPMIHN--GHHTSEN 169
K + + G P+ L + + LE A + +N GH+ +
Sbjct: 777 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 836
Query: 170 VG----------SIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPPTCEEARC 215
G + G S++ CE G++ G + I C L GK WS + P C A C
Sbjct: 837 PGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC-GAPC 895
Query: 216 KSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIF 275
P+G + P G+ S C + + + E F
Sbjct: 896 GGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSIKITFERF 940
Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRCTVDSQKT 332
+ H G +L + GS Y P+ NFI L T D+ ++
Sbjct: 941 QTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLFTTDNSRS 992
Query: 333 GTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQ 390
+G E ++ + C P I + GR ++ TV F+C G+ L +
Sbjct: 993 N--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEP 1047
Query: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEES 450
+ C W P C+ C VR GT + +PGY S
Sbjct: 1048 LLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGYPEFYPNS 1090
Query: 451 IQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLSGS----- 504
+ CT WT V K + + H ++ N S + +L+GS
Sbjct: 1091 LNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPT 1144
Query: 505 ----VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSSLEDFPYG 549
+Y + + + + + E IT C P + G+ G +F G
Sbjct: 1145 INAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF---NFGIG 1201
Query: 550 TTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIAN 609
T+T++C+ G + L G S I C R WS P P C +C N
Sbjct: 1202 DTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAECGASATNN 1248
Query: 610 GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLH- 668
+ P Y + +C ++ I A + V + H
Sbjct: 1249 EGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHL 1306
Query: 669 HGRHTGGNTVFFVSGMTVDYT--------------CDPGYLLV--GNKSIHCMPSGNWSP 712
G TG + + G+T+ T D G+ LV + HC P
Sbjct: 1307 LGAFTGAS----MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE-----DP 1357
Query: 713 SAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPL 772
P+ + S Q AGS + C GY L G + C E W +P
Sbjct: 1358 GIPQF-----GYKISDQGHFAGSTIIY---GCNPGYTLHGSSLLKCMTGERRAWDYPLPS 1409
Query: 773 CKVIHCHPPPVIVNGKHTGMMAE---NFLYGNEV----SYECDQG-FYLLGEKKLQCRSD 824
C + C G+ +G + F Y N + E D G L +
Sbjct: 1410 C-IAECGGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEAS 1465
Query: 825 SKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGS 884
W GP + ++ PE H LN + + Y+ + I S
Sbjct: 1466 HDILRVWDGPPENDMLLKEISGSLIPEGIHS-TLNIVTIQFDTD--FYISKSGFAIQFSS 1522
Query: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
V D PGVP NG G PG ++++ CD GY
Sbjct: 1523 SVATACRD----PGVPM----------------NGTRNGDG---REPGDTVVFQCDPGYE 1559
Query: 945 LVGEALLLC---THEGTWSQPAPHC 966
L GE + C + W P C
Sbjct: 1560 LQGEERITCIQVENRYFWQPSPPVC 1584
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 903 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 958
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 479 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 535
Query: 959 WSQPAPHCKEVNCSS 973
WS P CK C S
Sbjct: 536 WSDHRPVCKVKTCGS 550
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/251 (20%), Positives = 95/251 (37%), Gaps = 37/251 (14%)
Query: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKGC 661
+I NG ++ Y TVT+ C +G+ L+G S + C + W+ +P C C
Sbjct: 1706 NIMNGTRLG---MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC 1762
Query: 662 QS----------PPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP---SG 708
S P G N V+ ++ + ++ G + S+H + G
Sbjct: 1763 GSRSTGSEGTVLSPNYPKNYSVGHNCVYSIA-VPKEFVVF-GQFVFFQTSLHDVVEVYDG 1820
Query: 709 NWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK 768
S+ + H +SL L +G+++ + TS +T + ++
Sbjct: 1821 PTQQSSLLSSLSGSHSGESL-PLSSGNQITIRFTSVG---PITAKGFHFV--------YQ 1868
Query: 769 KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGH 828
+P C P G+ G F G+ V ++C+ G+ L G ++C +
Sbjct: 1869 AVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1925
Query: 829 GSWSGPSPQCL 839
W+ P C+
Sbjct: 1926 AQWNDSLPTCI 1936
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGR 476
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R
Sbjct: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMR 246
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 177 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
Query: 82 C 82
C
Sbjct: 235 C 235
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 486 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 542
Query: 838 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 885
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 543 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 601
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
+ G P + + G P I S M + D+
Sbjct: 602 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 649
Query: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 650 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 695
Query: 1006 LEGSPQSQCQSDHQWNPPLAVC 1027
L G CQ ++QW+ + +C
Sbjct: 696 LIGEKSIVCQENNQWSANIPIC 717
Score = 41.2 bits (95), Expect = 0.005
Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 33/256 (12%)
Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
CP P NG GS DF G+TV ++C+ ++ L G +I C + W
Sbjct: 486 CPDPGEPENGKRIGS---DFSLGSTVQFSCDE------DYVLQGAKSITCQRIAEVFAAW 536
Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
S P+CK+ S++ +G + P+ Y+ +C T ++++
Sbjct: 537 SDHRPVCKVKTCG---SNLQGPSG-TFTSPNFPFQYDSNA--QCVWVITAVNTNKVIQIN 590
Query: 647 DNTWDPEI-----PVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKS 701
+D EI + + G P TG FV + V + L ++S
Sbjct: 591 FEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGS----FVPDLIVSMSSQMWLHLQTDES 646
Query: 702 IHCMPSGNWSPSAPRCE-ETCQHVRQSLQELPAG---SRVELVNTSCQDGYQLTGHAYQM 757
+ S + + E E+C L + G S +++ CQ G++L G +
Sbjct: 647 V---GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIV 703
Query: 758 CQDAENGIWFKKIPLC 773
CQ EN W IP+C
Sbjct: 704 CQ--ENNQWSANIPIC 717
Score = 40.4 bits (93), Expect = 0.009
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 9/71 (12%)
Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
CP P NG+ IG+ S GS V ++CD D ++L G ++ C ++ W
Sbjct: 486 CPDPGEPENGKRIGSDF---SLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAW 536
Query: 336 SGPAPRCELST 346
S P C++ T
Sbjct: 537 SDHRPVCKVKT 547
Score = 40.4 bits (93), Expect = 0.009
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P P NG + VG I + C + LIG +L C+ V W+ P P+
Sbjct: 2223 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCL--HGVSRNWNHPLPR 2278
Query: 82 CE 83
CE
Sbjct: 2279 CE 2280
Score = 38.9 bits (89), Expect = 0.027
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 1700 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1757
Query: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
C P G + G S Y SV C + ++ V+ Q
Sbjct: 1758 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1804
Query: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 1805 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1863
Query: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 1864 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1914
Query: 253 SSRCVIAGQGVA-WT-KMPVC 271
+ RC +A W +P C
Sbjct: 1915 AIRCETVPNSLAQWNDSLPTC 1935
Score = 37.7 bits (86), Expect = 0.060
Identities = 74/300 (24%), Positives = 108/300 (36%), Gaps = 61/300 (20%)
Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCE 272
C G NGK + +G T F CDE Y LQG S C IA AW+ PVC+
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 273 EIFCPSPPPILNGRHIGNSL-----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTL 323
C S +G + +N ++T + + +NF + IG TL
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTL 603
Query: 324 RCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVI 376
D + G PR L Q+L G V S Q + D +
Sbjct: 604 TIG-DGGEVGD-----PRTVL----------QVLTGSFVPDLIVSMSSQMWLHLQTDESV 647
Query: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIK 436
+ F K ++ C GT P + E + +R ++RF+
Sbjct: 648 GSVGFKVNYKEIEKESCGDPGT--PLYGIREGD----------GFSNRDVLRFE------ 689
Query: 437 YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
C G+ L+GE+SI C W+ +P C + C + T P + PD G
Sbjct: 690 --CQFGFELIGEKSIVCQENNQWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 742
Score = 36.6 bits (83), Expect = 0.13
Identities = 65/272 (23%), Positives = 97/272 (35%), Gaps = 55/272 (20%)
Query: 344 LSTSAVQCPHPQILRGRMVSGQK--DRYTYNDTVIFACMFGFTLKGSKQIRC----NAQG 397
+ T++ CP P G +G++ ++ TV F+C + L+G+K I C
Sbjct: 479 IKTASNLCPDP----GEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 534
Query: 398 TWEPSAPVCE-KEC----QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-----G 447
W PVC+ K C Q P P +Y N V V
Sbjct: 535 AWSDHRPVCKVKTCGSNLQGPSGTFT-----------SPNFPFQYDSNAQCVWVITAVNT 583
Query: 448 EESIQCTSE------GVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKL 501
+ IQ E G T + T Q+LT FV PD+ S L
Sbjct: 584 NKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLT---GSFV-PDLIVSMSSQMWL 639
Query: 502 SGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
E G++ + + + ++ +C P G G + F + + C G
Sbjct: 640 HLQT-DESVGSVGFKVNYKEIEKESCGDPGTPLYGIREG---DGFSNRDVLRFECQFG-- 693
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
F LIGE +I C N+Q WS P+C
Sbjct: 694 ----FELIGEKSIVCQENNQ----WSANIPIC 717
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 965
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 178 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
Query: 966 CK 967
C+
Sbjct: 235 CR 236
Score = 35.8 bits (81), Expect = 0.23
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 1026 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 1068
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 9/81 (11%)
Query: 154 CPALPMIHNGHHTSENVGS-IAPGLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPP 208
CP NG + +GS + G +V +SC+ Y+L G K I C + WS P
Sbjct: 486 CPDPGEPENG----KRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRP 541
Query: 209 TCEEARCKSLGRFPNGKVKEP 229
C+ C S + P+G P
Sbjct: 542 VCKVKTCGSNLQGPSGTFTSP 562
Score = 34.7 bits (78), Expect = 0.51
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 838
F G+++ Y C G+ L G +L C ++S SW P P C
Sbjct: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 1022
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 171 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
Query: 1023 PLAVCRS 1029
P+ +CR+
Sbjct: 231 PVPICRA 237
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137
SSC P VP + G T + GD + ++C T + ++G+ + C AN++
Sbjct: 176 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 223
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
CP+P P K GS + G +V F+C ++ + G KS+ CQ
Sbjct: 486 CPDPGEPENGKRIGSD-FSLGSTVQFSCDEDYVLQGAKSITCQ 527
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 14/73 (19%)
Query: 522 CKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQ 581
C PP V+Y F G + Y+C G + L G + C +N
Sbjct: 178 CGNPGVPPKGVLYGTR--------FDVGDKIRYSCVTG------YILDGHPQLTCIANSV 223
Query: 582 ERGTWSGPAPLCK 594
+W P P+C+
Sbjct: 224 NTASWDFPVPICR 236
Score = 31.2 bits (69), Expect = 5.6
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 176 GLSVTYSCESGYLLVGEKIINCL----SSGKWSAVPPTCE-EARCKSLGRFPNGKVKEP 229
G + YSC +GY+L G + C+ ++ W P C E C R +G + P
Sbjct: 197 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSP 255
Score = 31.2 bits (69), Expect = 5.6
Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C P NG+ + ++G+ +++SC + L G KS+ C +V W P C
Sbjct: 486 CPDPGEPENGK--RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 543
Query: 83 E 83
+
Sbjct: 544 K 544
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 333 bits (853), Expect = 7e-91
Identities = 294/1082 (27%), Positives = 426/1082 (39%), Gaps = 144/1082 (13%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C PPP+ N I +G +IRY C F L+G L C +++ D P C
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQ--MDGAPPVC 2348
Query: 83 E--------------------YFNKYSS---CPEPI-VPGGYKIRG-------------- 104
+ Y + Y + C I V GY I
Sbjct: 2349 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVL 2408
Query: 105 --------STPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPA 156
+P S ++ N + NG++ V+ Q + G + + C
Sbjct: 2409 QVYDGPNIQSPVLISLSGDYSSAFNITSNGHE-VFLQWSADHGNNKKGFRIRYIAFYCST 2467
Query: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG----KWSAVPPTCEE 212
+G+ S+ G + V ++C+ G+ LVG+ C S W A P C+
Sbjct: 2468 PESPPHGYIISQTGGQL--NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQA 2525
Query: 213 ARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT---KMP 269
C NG + L VG +FC++GYRL + V G W+ K P
Sbjct: 2526 ISCGIPKAPTNGGILTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSNHNKTP 2583
Query: 270 VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDS 329
C I C P NG IG SYGS +TCD + F+L+G + C
Sbjct: 2584 RCVVISCGELPTPPNGNKIGTQ---TSYGSTAIFTCD------LGFMLVGSAVRECL--- 2631
Query: 330 QKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSK 389
+G WS RC A C P+++ V G+ Y Y DTV++ C GF L GS
Sbjct: 2632 -SSGLWSESETRC----LAGHCGIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSS 2684
Query: 390 QIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGE 448
C W P C C P + + G+ F+ + +SCN GY++ G
Sbjct: 2685 VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNG---FNFNDVVTFSCNIGYLMQGP 2741
Query: 449 ESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD------VNSSCGEGYKLS 502
QC + W+ P P CKV C G +K + + + V C GY L
Sbjct: 2742 TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLF 2801
Query: 503 GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPER 562
GS CQ W + C I C P V N +G E + +G+TV Y+C
Sbjct: 2802 GSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSCTG---- 2854
Query: 563 GVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFY 622
+ SL+G+S+ C N G WSG P C +G S +E+ +
Sbjct: 2855 --KRSLLGQSSRTCQLN----GHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRT 2905
Query: 623 NDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVS 682
TV + C +G+ L GS + C A+ +W P C+ PG T VF +
Sbjct: 2906 KSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT-----TANGKVFRID 2960
Query: 683 GMT----VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-TCQHVRQSLQELPAGSRV 737
G T V Y+C GY+L G C +G WS + P C +C L G
Sbjct: 2961 GTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDY 3020
Query: 738 EL---VNTSCQDGY--QLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGM 792
+ V+ CQ GY +L G + C NG W +P C+ + C PP I NG+ G
Sbjct: 3021 VVGQNVSYMCQPGYTMELNGSRIRTC--TINGTWSGVMPTCRAVTCPTPPQISNGRLEGT 3078
Query: 793 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV 852
NF +G +SY C G+ L L C G+G+WSG PQCL C +P +
Sbjct: 3079 ---NFDWGFSISYICSPGYELSFPAVLTC----VGNGTWSGEVPQCLPK----FCGDPGI 3127
Query: 853 KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPP 912
K + ++ + V CN FI+ GS C D TW P CI+ C
Sbjct: 3128 PAQGK--REGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCEN 3185
Query: 913 P--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P P+ + N+T G F G + + C +G+LL G C + TWS P C +
Sbjct: 3186 PGVPRHGSQNNTFG----FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHS 3241
Query: 971 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQ-CQSDHQWNPPLAVCRS 1029
C P + + +G + C+ G+ L G + + C+SD+ W + +C +
Sbjct: 3242 CKQPE--TPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
Query: 1030 RS 1031
S
Sbjct: 3300 GS 3301
Score = 225 bits (573), Expect = 2e-58
Identities = 188/661 (28%), Positives = 270/661 (40%), Gaps = 75/661 (11%)
Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
P + +SCG P + GR S V+ +SC+ + + G C + + W
Sbjct: 2699 PSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQGPTKAQC----QANRQW 2752
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWC 132
P P C+ N C +P +P K + +G V + C + + G+ + C
Sbjct: 2753 SHPPPMCKVVN----CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLIC 2808
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Q N W LP C+ + +C + N + E G +V YSC L+G+
Sbjct: 2809 QPNGQWDKP-LPECIMI---DCGHPGVPPNAVLSGE---KYTFGSTVHYSCTGKRSLLGQ 2861
Query: 193 KIINCLSSGKWSAVPPTCE---EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQ 249
C +G WS P C C G +G +E R T + CD GY L
Sbjct: 2862 SSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESN-FRTKSTVRYACDTGYILH 2920
Query: 250 GPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
G C+ G +WT + P C+ + C +P NG+ + ++ S V Y+C
Sbjct: 2921 GSEERTCLANG---SWTGRQPECKAVQCGNPGTTANGKVF--RIDGTTFSSSVIYSC--- 2972
Query: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDR 368
EG +IL G S +CT + GTWSG P C + + C P I + G D
Sbjct: 2973 -MEG--YILSGPSVRQCTAN----GTWSGTLPNCTI----ISCGDPGIPANGLRYG--DD 3019
Query: 369 YTYNDTVIFACMFGFT--LKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNILNGQKEDRH 425
Y V + C G+T L GS+ C GTW P C C PP I NG+ E
Sbjct: 3020 YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEG-- 3077
Query: 426 MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
FD G SI Y C+PGY L + C G W+ VPQC C G K + +
Sbjct: 3078 -TNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGK 3136
Query: 486 --FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT---CPPPPVIYNGAHTG 540
+ +V+ SC + L GS + CQ W C E T C P V +G+
Sbjct: 3137 SFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNN 3196
Query: 541 SSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAV 600
+ F G+ V + C G L+ ST R D TWSG P C +
Sbjct: 3197 TF--GFQVGSVVQFHCKKG-------HLLQGSTTRTCLPDL---TWSGIQPEC----IPH 3240
Query: 601 QCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR-CKADNTWDPEIPVCEK 659
C + G + P + T+ + C GF L G ++ R C++DNTW ++P+CE
Sbjct: 3241 SCKQPETPAHANVVGMDLP-SHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEA 3299
Query: 660 G 660
G
Sbjct: 3300 G 3300
Score = 198 bits (504), Expect = 2e-50
Identities = 223/907 (24%), Positives = 348/907 (38%), Gaps = 143/907 (15%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLS--SGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
G ++++ C GY L+G + CL S W+ P CE A C NG + P
Sbjct: 2139 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE-ALCGGNITAMNGTIYSP---- 2193
Query: 234 VGVTANF--FCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNS 291
G + F D + ++ PP + I P+ + I P N IG
Sbjct: 2194 -GYPDEYPNFQDCFWLVRVPPGNGIYI--NFTVLQTEPIYDFITVWDGPD-QNSPQIGQF 2249
Query: 292 LANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ- 350
N + S+ + + N ILI + D +G + LS A Q
Sbjct: 2250 SGNTALESVYSTS---------NQILI-----KFHSDFTTSGFFV-------LSYHAYQL 2288
Query: 351 --CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA--QGTWEPSAPVC 406
C P + + + D + D + + C+ GFTL G+ + C + + + PVC
Sbjct: 2289 RVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVC 2348
Query: 407 EKECQAPPNILNGQKEDRHMVRFDPGTSIKY----------SCNPGY-VLVGEESIQCTS 455
+ C A N + D V PG Y S GY + + E Q
Sbjct: 2349 QVLCPA-----NELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK 2403
Query: 456 E----GVWTPPVPQCKVAAC---EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQE 508
E V+ P Q V + + +T H+ + S G G
Sbjct: 2404 EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVF---LQWSADHGNNKKG----- 2455
Query: 509 CQGTIPWFMEIRLCKEITCPP--PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEF 566
IR P PP Y + TG L + V + C+ G F
Sbjct: 2456 --------FRIRYIAFYCSTPESPPHGYIISQTGGQLN-----SVVRWACDRG------F 2496
Query: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTV 626
L+G+S+ C + W P P C+ A+ C I + Y V
Sbjct: 2497 RLVGKSSAVCRKSSYGYHAWDAPVPACQ----AISCGIPKAPTNGGILTTD--YLVGTRV 2550
Query: 627 TFKCYSGFTL--KGSSQIRCKADNTWDP--EIPVCEK-GCQSPPGLHHGRHTGGNTVFFV 681
T+ C G+ L K + C++D TW + P C C P +G G T +
Sbjct: 2551 TYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSY-- 2608
Query: 682 SGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV---- 737
G T +TCD G++LVG+ C+ SG WS S RC H + EL +V
Sbjct: 2609 -GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC--LAGHC--GIPELIVNGQVIGEN 2663
Query: 738 ----ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMM 793
+ V C G++L G + ++CQ N W ++P C + C P + G+ +G
Sbjct: 2664 YGYRDTVVYQCNPGFRLIGSSVRICQQDHN--WSGQLPSCVPVSCGHPGSPIYGRTSG-- 2719
Query: 794 AENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVK 853
F + + V++ C+ G+ + G K QC+++ + WS P P C V C +P +
Sbjct: 2720 -NGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ----WSHPPPMC----KVVNCSDPGIP 2770
Query: 854 HGYKLNKT--HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
K H +++ +V+ DCNPG+ + GS V+ C + W +P CI I C
Sbjct: 2771 ANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI---MIDCG 2827
Query: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
P PN +G +++ G ++ YSC L+G++ C G WS PHC
Sbjct: 2828 HPGVPPNAVLSG---EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDAT 2884
Query: 972 SSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRS 1031
+ D G ++ + V C+ GY+L GS + C ++ W C++
Sbjct: 2885 GTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKA-- 2942
Query: 1032 LAPVLCG 1038
V CG
Sbjct: 2943 ---VQCG 2946
Score = 99.0 bits (245), Expect = 2e-20
Identities = 78/276 (28%), Positives = 114/276 (41%), Gaps = 24/276 (8%)
Query: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
V P ++C +PP I NGR+ T G I Y CS + L L C+ +G
Sbjct: 3055 VMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYELSFPAVLTCVG----NG 3108
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
TW P+C K+ C +P +P K G + + + V+F+C F + G+ + CQ
Sbjct: 3109 TWSGEVPQC--LPKF--CGDPGIPAQGKREGKS-FIYQSEVSFSCNFPFILVGSSTRICQ 3163
Query: 134 ANNMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
A+ W + P C+ C P +P H + N G V + C+ G+LL G
Sbjct: 3164 ADGTWSGSS-PHCIEPTQTSCENPGVPR----HGSQNNTFGFQVGSVVQFHCKKGHLLQG 3218
Query: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
CL WS + P C CK + V + G T + C G+ L G
Sbjct: 3219 STTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG 3278
Query: 252 PSSRCVIAGQGVAWT-KMPVCE---EIFCPSPPPIL 283
R + WT K+P+CE +I P P L
Sbjct: 3279 TEHR--VCRSDNTWTGKVPICEAGSKILVKDPRPAL 3312
Score = 82.0 bits (201), Expect = 3e-15
Identities = 214/1039 (20%), Positives = 328/1039 (31%), Gaps = 272/1039 (26%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK----WSAVPPTCEEARCKSLGRFPNGKVKEPPI 231
G +VTY C++GY+L G + C+ W+ P+C A C S G V P
Sbjct: 1616 GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCH-APCGSRSTGSEGTVLSP-- 1672
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFC-----PSPPPILNG 285
N+ V+ GQ V + T + E++ S L+G
Sbjct: 1673 ---NYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1729
Query: 286 RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELS 345
H G SL S I P F + ++ R
Sbjct: 1730 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPR--------------------- 1768
Query: 346 TSAVQC---PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGT 398
TS+ QC P P+ GR + + + +V+F C G+ L GS IRC N+
Sbjct: 1769 TSSTQCSSVPEPRF--GRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W S P C C IL +K GT + +PGY + ++ C V
Sbjct: 1824 WNDSLPTCIVPCGG---ILTKRK----------GTIL----SPGYPEPYDNNLNC----V 1862
Query: 459 WTPPVP-------QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-----KLSGSVY 506
W VP Q A E L P + S G S ++Y
Sbjct: 1863 WKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLY 1922
Query: 507 QECQGTIP-----WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Q I + +E +CP P +G G + + G V++ C+ G
Sbjct: 1923 LNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCDQG-- 1977
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK---ISGKEA 618
+SL G S I C R + P L + S V ++ G+ S +
Sbjct: 1978 ----YSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDC 2033
Query: 619 PYFYNDTVTFKCYSGFT-------------LKGSSQIRCKADNTWDPEIPVCE------- 658
+ N + F + F GSS+ P+IP
Sbjct: 2034 TWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHET 2093
Query: 659 ------------------------KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY 694
+ C P +G G + F G T+ + C PGY
Sbjct: 2094 SLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGND---FTVGQTISFECFPGY 2150
Query: 695 LLVGNKSIHCM--PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTG 752
L+GN ++ C+ S NW+ PRCE C G+ + T GY
Sbjct: 2151 TLIGNSALTCLHGVSRNWNHPLPRCEALC-----------GGNITAMNGTIYSPGYPDEY 2199
Query: 753 HAYQMCQDAENGIWFKKIP-------LCKVIHCHPPPVIVN------------GKHTGMM 793
+Q C W ++P V+ P + G+ +G
Sbjct: 2200 PNFQDC------FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNT 2253
Query: 794 AENFLYGNE----VSYECD---QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTR 846
A +Y + + D GF++L Q R C PPV
Sbjct: 2254 ALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR--------------VCQPPPPV-- 2297
Query: 847 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT-DNTWVPGVPTCIKK 905
PN E+ + DI+ C PGF + G+ ++ C + + G P +
Sbjct: 2298 -PNAEIL------TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ- 2349
Query: 906 AFIGCPP----------------PPKTPN--------GNHTGGNIARFSPGMSILYSCDQ 941
+ CP P PN G NI F D
Sbjct: 2350 --VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDV 2407
Query: 942 GYLLVG---EALLLCTHEGTWSQP---APHCKEVNCSSPADMDGIQKGLEPRKMYQY--- 992
+ G ++ +L + G +S + EV AD +KG R + Y
Sbjct: 2408 LQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCST 2467
Query: 993 -----------------GAVVTLECEDGYMLEGSPQSQCQSD----HQWNPPLAVCRSRS 1031
+VV C+ G+ L G + C+ H W+ P+ C++ S
Sbjct: 2468 PESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS 2527
Query: 1032 LAPVLCGIAAGLILLTFLI 1050
G++ +L+
Sbjct: 2528 CGIPKAPTNGGILTTDYLV 2546
Score = 80.5 bits (197), Expect = 8e-15
Identities = 156/664 (23%), Positives = 237/664 (35%), Gaps = 164/664 (24%)
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG--VWTPPVPQCKVAACEATGRQ---LLTKPQ 483
F G ++ +SC+ GY L G I C G VW+ P+P+C VA C A+ +L P
Sbjct: 1094 FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC-VAECGASATNNEGILLSPN 1152
Query: 484 HQFVRPDVNSSC--------GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN 535
+ + + N C G+G +S + QG + ++I K+ T
Sbjct: 1153 YP-LNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---LKIYDGKDKTTH-----LL 1203
Query: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
GA TG+S+ G T++ T N + +EF N GT G L
Sbjct: 1204 GAFTGASMR----GLTLSSTSN---QLWLEF------------NSDTEGTDEG-FQLVYT 1243
Query: 596 SLLAVQCSHVHIAN-GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD--NTWDP 652
S C I GYKIS + +F T+ + C G+TL GSS ++C WD
Sbjct: 1244 SFELSHCEDPGIPQFGYKIS--DQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1301
Query: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM-----PS 707
+P C C GR G ++ +S PGY + ++ CM
Sbjct: 1302 PLPSCIAEC-------GGRFKGESSGRILS---------PGYPFPYDNNLRCMWMIEVDP 1345
Query: 708 GN--------------------WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDG 747
GN W P + + + SL S + +V
Sbjct: 1346 GNIVSLQFLAFDTEASHDILRVWD-GPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTD 1404
Query: 748 YQL--TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSY 805
+ + +G A Q C P V +NG G E G+ V +
Sbjct: 1405 FYISKSGFAIQFSSSVATA-------------CRDPGVPMNGTRNGDGREP---GDTVVF 1448
Query: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP---NPEVKHGYKLNKTH 862
+CD G+ L GE+++ C + W SPPV P N G+ L+
Sbjct: 1449 QCDPGYELQGEERITC-IQVENRYFWQ-------PSPPVCIAPCGGNLTGSSGFILSPNF 1500
Query: 863 -SAYSHNDIVYVDCNPGFIMNGSRVIRC---------HTDNTWVPGVPTCIKKAFIGCPP 912
Y H+ DC+ +N VI + D ++ P IG
Sbjct: 1501 PHPYPHSR----DCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDS-NSPLIGSFQ 1555
Query: 913 PPKTPNGNHTGGNIAR--FSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
K P + N F S+ Y+ G+ L +A L +
Sbjct: 1556 DSKLPERIESSSNTMHLAFRSDGSVSYT---GFHLEYKAKL----------------RES 1596
Query: 971 CSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC----QSDHQWNPPLA 1025
C P + M+G + G++ Y+ G+ VT C+ GY+L+G C WN L
Sbjct: 1597 CFDPGNIMNGTRLGMD----YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
Query: 1026 VCRS 1029
C +
Sbjct: 1653 SCHA 1656
Score = 72.4 bits (176), Expect = 2e-12
Identities = 138/646 (21%), Positives = 228/646 (35%), Gaps = 124/646 (19%)
Query: 233 RVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWTK-MPVCEEIFCPSPPPILNGRHIG- 289
++G T ++CD GY LQG + C++ G W + +P C C S G +
Sbjct: 1614 KLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAP-CGSRSTGSEGTVLSP 1672
Query: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAV 349
N N S G Y+ E F++ G+ T + GP + L +S
Sbjct: 1673 NYPKNYSVGHNCVYSIAVPKE----FVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLS 1728
Query: 350 QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE 409
+ L + SG + T+ F + T KG + ++ +
Sbjct: 1729 GSHSGESLP--LSSGNQI------TIRFTSVGPITAKGFHFV-------YQAVPRTSSTQ 1773
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQ 465
C + P G++ F G+S+ + CNPGY+L G +I+C S W +P
Sbjct: 1774 CSSVPEPRFGRRIGNE---FAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPT 1830
Query: 466 CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEI 525
C + C +LTK + + P Y E P+ + +I
Sbjct: 1831 C-IVPCGG----ILTKRKGTILSPG---------------YPE-----PYDNNLNCVWKI 1865
Query: 526 TCPP------PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSN 579
T P V + H SL+ + G N P G + TSN
Sbjct: 1866 TVPEGAGIQVQVVSFATEHNWDSLDFYDGGD------NNAPRLGSYSGTTIPHLLNSTSN 1919
Query: 580 D---QERGTWSGPAPLCKLSLLAV---QCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYS 632
+ + S A L A+ C ++G KI + Y D V+F+C
Sbjct: 1920 NLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR---YMVGDVVSFQCDQ 1976
Query: 633 GFTLKGSSQIRCKAD--NTWDPEIPVCEKGCQS----------PPGLHHGRHTGGNTVFF 680
G++L+G S I C W+ IP+C C PG G + +
Sbjct: 1977 GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGF-PGNYPSSLDCTW 2035
Query: 681 VSGMTVDYTCDPGYLLVGNKSIHC---MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
+ + + ++ ++IH + SG+ S + + SL + +
Sbjct: 2036 TINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSL 2095
Query: 738 ELVNTSCQD--GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE 795
+ Q+ G+ + AYQ+ C P NG ++
Sbjct: 2096 YFHSDYSQNKQGFHIVYQAYQLQS------------------CPDPRPFRNG---FVIGN 2134
Query: 796 NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPSPQC 838
+F G +S+EC G+ L+G L C HG +W+ P P+C
Sbjct: 2135 DFTVGQTISFECFPGYTLIGNSALTCL-----HGVSRNWNHPLPRC 2175
Score = 62.4 bits (150), Expect = 2e-09
Identities = 145/624 (23%), Positives = 214/624 (34%), Gaps = 142/624 (22%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G +V++SC+SGY L E+ + C + WS PTC +A C R P+G + P
Sbjct: 925 GSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC-DALCGGDVRGPSGTILSP------ 977
Query: 236 VTANFFCDEGYRLQGPPSSRC-----VIAGQGVAWT-----------KMPVCEEIFCPSP 279
GY P S C V G+GV + + + E P
Sbjct: 978 ---------GYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQP 1028
Query: 280 ---------PPILNGRHIGNSLA--------NVSY-GSIVT---YTCDPDPEEGV----- 313
PP +N GN A ++SY G +T Y +P + G+
Sbjct: 1029 LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGS 1088
Query: 314 ----NFILIGESTLRCTVDSQKTGT------------WSGPAPRCELSTSAVQCPHPQIL 357
NF + T C+ + GT WS P PRC A + IL
Sbjct: 1089 RIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGIL 1148
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNIL 417
Y N C++ ++ K I +A+ V + I
Sbjct: 1149 -------LSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLK--------IY 1193
Query: 418 NGQKEDRHMVRFDPGTSIK----YSCNPGYVLVGEESIQCTSEG---VWTP-PVPQCKVA 469
+G+ + H++ G S++ S + L + T EG V+T + C+
Sbjct: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1253
Query: 470 ACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ--GTIPWFMEIRLCKEITC 527
G ++ Q F + C GY L GS +C W + C C
Sbjct: 1254 GIPQFGYKI--SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAEC 1310
Query: 528 PPPPVIYNGAHTGSSLE---DFPYGTTV----TYTCNPGPERGVEFSLIGESTIRCTSND 580
+ G +G L FPY + +PG ++F S+D
Sbjct: 1311 GGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1363
Query: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSS 640
R W GP + +L + S I G S DT + SGF ++ SS
Sbjct: 1364 ILR-VWDGPP---ENDMLLKEISGSLIPEGIH-STLNIVTIQFDTDFYISKSGFAIQFSS 1418
Query: 641 QIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
+ A DP +P+ +G G G TV + CDPGY L G +
Sbjct: 1419 SV---ATACRDPGVPM------------NGTRNGDGR---EPGDTVVFQCDPGYELQGEE 1460
Query: 701 SIHCMPSGN---WSPSAPRCEETC 721
I C+ N W PS P C C
Sbjct: 1461 RITCIQVENRYFWQPSPPVCIAPC 1484
Score = 58.9 bits (141), Expect = 3e-08
Identities = 134/619 (21%), Positives = 214/619 (34%), Gaps = 128/619 (20%)
Query: 43 VGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC-------------------- 82
+G + +SCS +RL G ++C+ + W P P+C
Sbjct: 1096 IGDTLTFSCSSGYRLEGTSEIICLGGGR--RVWSAPLPRCVAECGASATNNEGILLSPNY 1153
Query: 83 --EYFNKYSSCPEPIVPGGYKIRGSTPYRH---GDSV-----------TFACKTNFSMNG 126
Y N + V G I S H GD + T SM G
Sbjct: 1154 PLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
Query: 127 ------NKSVWCQANNMW-----GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP 175
+ +W + N+ G + T + E P +P G+ S+ G A
Sbjct: 1214 LTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ-GHFA- 1269
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILR 233
G ++ Y C GY L G ++ C++ + W P+C A C GRF
Sbjct: 1270 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG--GRFK----------- 1315
Query: 234 VGVTANFFCDEGYRLQGPPSSRC----------VIAGQGVAWTKMPVCEEIFCPSPPPIL 283
G ++ GY + RC +++ Q +A+ + + PP
Sbjct: 1316 -GESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPP-- 1372
Query: 284 NGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
+ L GS++ EG++ L + + D+ + SG A +
Sbjct: 1373 ----ENDMLLKEISGSLI--------PEGIHSTL---NIVTIQFDTDFYISKSGFAIQFS 1417
Query: 344 LSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC---NAQGTWE 400
S+ A C P + +G D DTV+F C G+ L+G ++I C + W+
Sbjct: 1418 -SSVATACRDPGVPMNGTRNG--DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQ 1474
Query: 401 PSAPVCEKECQAPPNILNG---QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
PS PVC C +G H + N YV+ S+ S
Sbjct: 1475 PSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVI----SLAFISFS 1530
Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE---GYKLSGSVYQECQGTIP 514
+ P + + L+ Q + + SS ++ GSV
Sbjct: 1531 I-EPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV-----SYTG 1584
Query: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
+ +E + +C P I NG G D+ G+TVTY C+ G + L G ST+
Sbjct: 1585 FHLEYKAKLRESCFDPGNIMNGTRLGM---DYKLGSTVTYYCDAG------YVLQGYSTL 1635
Query: 575 RCTSNDQERGTWSGPAPLC 593
C D R W+ P C
Sbjct: 1636 TCIMGDDGRPGWNRALPSC 1654
Score = 57.8 bits (138), Expect = 6e-08
Identities = 109/481 (22%), Positives = 163/481 (33%), Gaps = 115/481 (23%)
Query: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPP 208
P E P +P G N G G ++T+SC SGY L G I CL G+ WSA P
Sbjct: 1077 PCEDPGIPQY--GSRIGFNFGI---GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLP 1131
Query: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
C A C + G + P Y L + C+ + Q A
Sbjct: 1132 RC-VAECGASATNNEGILLSP---------------NYPLNYENNHECIYSIQVQAG--- 1172
Query: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
G +I +++ G ++ D + G S T+
Sbjct: 1173 ---------------KGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLS 1217
Query: 329 SQKTGTW-------SGPAPRCELSTSAVQCPH------PQILRGRMVSGQKDRYTYNDTV 375
S W G +L ++ + H PQ G +S Q + T+
Sbjct: 1218 STSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQF--GYKISDQ--GHFAGSTI 1273
Query: 376 IFACMFGFTLKGSKQIRC--NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
I+ C G+TL GS ++C + W+ P C EC RF G
Sbjct: 1274 IYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG---------------RF-KGE 1317
Query: 434 SIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR----P 489
S +PGY + +++C +W V + + + T+ H +R P
Sbjct: 1318 SSGRILSPGYPFPYDNNLRC----MWMIEVDPGNIVSLQFLAFD--TEASHDILRVWDGP 1371
Query: 490 DVNSSCGEGYKLSGSVYQECQG------TIPWFMEIRLCKE-----------ITCPPPPV 532
N + ++SGS+ E TI + + + K C P V
Sbjct: 1372 PENDMLLK--EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGV 1429
Query: 533 IYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPL 592
NG G E G TV + C+PG + L GE I C + R W P+
Sbjct: 1430 PMNGTRNGDGREP---GDTVVFQCDPG------YELQGEERITCI-QVENRYFWQPSPPV 1479
Query: 593 C 593
C
Sbjct: 1480 C 1480
Score = 54.3 bits (129), Expect = 6e-07
Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 48/286 (16%)
Query: 631 YSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTC 690
Y+GF L+ +++R + C P + +G G + + G TV Y C
Sbjct: 1582 YTGFHLEYKAKLR---------------ESCFDPGNIMNGTRLGMD---YKLGSTVTYYC 1623
Query: 691 DPGYLLVGNKSIHCMPSGN----WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQD 746
D GY+L G ++ C+ + W+ + P C C GS +++ +
Sbjct: 1624 DAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC-------GSRSTGSEGTVLSPNYPK 1676
Query: 747 GYQLTGH--AYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVS 804
Y + GH Y + E ++ + + +H V + G ++ L +
Sbjct: 1677 NYSV-GHNCVYSIAVPKEFVVFGQFVFFQTSLH------DVVEVYDGPTQQSSLLSSLSG 1729
Query: 805 YECDQGFYLLGEKKLQCRSDSKGHGSWSGPS--PQCLRSPPVTRCPN-PEVKHGYKLNKT 861
+ L ++ R S G + G Q + T+C + PE + G ++
Sbjct: 1730 SHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG-- 1787
Query: 862 HSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGVPTCI 903
+ ++ V DCNPG+I++GS IRC T W +PTCI
Sbjct: 1788 -NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCI 1832
Score = 52.4 bits (124), Expect = 2e-06
Identities = 123/519 (23%), Positives = 181/519 (34%), Gaps = 101/519 (19%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG+P G + Y T VG IRYSC + L G L CI +WD P P
Sbjct: 177 SCGNPGVPPKGVL--YGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
Query: 82 CEYFNKYSS--------CPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGNKS 129
C + P P Y + GD+++ T+F M K
Sbjct: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-TDFQME-EKY 292
Query: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGH----HTSENVGSIAPGLSVTYSCES 185
+ + PT + +++ P P+I N + H + G S Y +
Sbjct: 293 DYLEIEGSEPPTIWLSGMNIPP------PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 346
Query: 186 -------GYLLVGEKIINCLSSGKWSAVPP---TCEEARCKSLGRFPNGKVKEPPILRVG 235
G+ L K +S K+S + C G NGK + +G
Sbjct: 347 AIDFKSRGFKLFPGKD----NSNKFSILNEGGIKTASNLCPDPGEPENGK-RIGSDFSLG 401
Query: 236 VTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSL- 292
T F CDE Y LQG S C IA AW+ PVC+ C S +G +
Sbjct: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
Query: 293 ----ANVSYGSIVTYTCDPDPEEGVNF----ILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
+N ++T + + +NF + IG TL D + G PR L
Sbjct: 462 FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDTLTIG-DGGEVGD-----PRTVL 514
Query: 345 STSAVQCPHPQILRGRMV-------SGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQG 397
Q+L G V S Q + D + + F K ++ C G
Sbjct: 515 ----------QVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPG 564
Query: 398 TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
T P + E + +R ++RF+ C G+ L+GE+SI C
Sbjct: 565 T--PLYGIREGD----------GFSNRDVLRFE--------CQFGFELIGEKSIVCQENN 604
Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCG 496
W+ +P C + C + T P + PD G
Sbjct: 605 QWSANIPIC-IFPCLSN----FTAPMGTVLSPDYPEGYG 638
Score = 51.2 bits (121), Expect = 5e-06
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 59/252 (23%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P + V+G+ G +F G+ VS+ CD G+ L E+ L C K H WS P P
Sbjct: 906 CLDPGIPVHGRRYG---HDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHW-WSHPLPT 958
Query: 838 C-------LRSPPVTRC--------PNP-------EVKHGYKLN---KTHSAYSHNDIVY 872
C +R P T PN +V HG + T H+D +
Sbjct: 959 CDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLL 1018
Query: 873 VDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKA--FIG--------------------C 910
+ N F +R+ T G+ + FI C
Sbjct: 1019 ITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPC 1078
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHCKE 968
P G+ G N F G ++ +SC GY L G + ++C G WS P P C
Sbjct: 1079 EDPGIPQYGSRIGFN---FGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
Query: 969 VNCSSPADMDGI 980
+S + +GI
Sbjct: 1136 ECGASATNNEGI 1147
Score = 49.7 bits (117), Expect = 2e-05
Identities = 107/501 (21%), Positives = 171/501 (34%), Gaps = 122/501 (24%)
Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGV----WTPPVPQCKVA-ACEATGRQ---LL 479
RFD G I+YSC GY+L G + C + V W PVP C+ AC T R ++
Sbjct: 193 RFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII 252
Query: 480 TKPQHQFVRPDVNSSC--------GEGYKLSGSVYQ--------ECQGTIP---WFMEIR 520
+ P + N+ C G+ L + +Q E +G+ P W +
Sbjct: 253 SSPSFPNEYHN-NADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMN 311
Query: 521 LCKEITCPPPPVIYNG----AHTGSSLEDFPYGTTVTYTCN-------------PGPERG 563
+ PPP+I N H + G + Y PG +
Sbjct: 312 I-------PPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKLFPGKDNS 364
Query: 564 VEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYN 623
+FS++ E I+ SN LC NG +I + +
Sbjct: 365 NKFSILNEGGIKTASN------------LCP--------DPGEPENGKRIG---SDFSLG 401
Query: 624 DTVTFKCYSGFTLKGSSQIRCK----ADNTWDPEIPV-----CEKGCQSP------PGLH 668
TV F C + L+G+ I C+ W PV C Q P P
Sbjct: 402 STVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFP 461
Query: 669 HGRHTGGNTVFFVSGMTVDYTCDPGY----LLVGNKSIHCMPSGNWSPSAPRCEETCQHV 724
+ V+ ++ + + + L +G ++ G
Sbjct: 462 FQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDP----------- 510
Query: 725 RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVI 784
R LQ L GS V + S L + + +K+I + C P
Sbjct: 511 RTVLQVL-TGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEI---EKESCGDPGTP 566
Query: 785 VNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL----- 839
+ G G + F + + +EC GF L+GEK + C+ +++ WS P C+
Sbjct: 567 LYGIREG---DGFSNRDVLRFECQFGFELIGEKSIVCQENNQ----WSANIPICIFPCLS 619
Query: 840 -RSPPVTRCPNPEVKHGYKLN 859
+ P+ +P+ GY N
Sbjct: 620 NFTAPMGTVLSPDYPEGYGNN 640
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/414 (21%), Positives = 146/414 (35%), Gaps = 88/414 (21%)
Query: 616 KEAPYFYN-DTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPV----CEKGCQSPPGL--- 667
+E F N D + F+C GF L G I C+ +N W IP+ C +P G
Sbjct: 571 REGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLS 630
Query: 668 -HHGRHTGGN-----TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-T 720
+ G N T+ G + + + + L + G+ SP +P T
Sbjct: 631 PDYPEGYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFT 688
Query: 721 CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 780
V L S ++ Q + ++G + + + C
Sbjct: 689 GAEVPSHLT-----SNSHILRLEFQADHSMSGRGFNITYNTFGHN-----------ECPD 732
Query: 781 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCL 839
P + +N + G +NF G+ +S C++GF G + + C G WSG P+C
Sbjct: 733 PGIPINARRFG---DNFQLGSSISVICEEGFIKTQGTETITCIL-MDGKVMWSGLIPKCG 788
Query: 840 R------SPPVTRCPNP----------------EVKHGYKLNKTHSAYS---HNDIVYVD 874
S P +P E + G+ + T + + D++ V
Sbjct: 789 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 848
Query: 875 CNPGFIM------NGSRV------------IRCHTDNTWVP-GVPTCIKKAFIG---CPP 912
P + NG++V + TDN+ G + + C
Sbjct: 849 DGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLD 908
Query: 913 PPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC 966
P +G G + FS G ++ +SCD GY L E LLC WS P P C
Sbjct: 909 PGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC 959
Score = 45.1 bits (105), Expect = 4e-04
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 7/75 (9%)
Query: 903 IKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTH----EGT 958
IK A CP P + NG G + FS G ++ +SCD+ Y+L G + C
Sbjct: 375 IKTASNLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
Query: 959 WSQPAPHCKEVNCSS 973
WS P CK C S
Sbjct: 432 WSDHRPVCKVKTCGS 446
Score = 45.1 bits (105), Expect = 4e-04
Identities = 56/247 (22%), Positives = 85/247 (34%), Gaps = 78/247 (31%)
Query: 651 DPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNW 710
DP IPV HGR G + F G TV ++CD GY L + + C + W
Sbjct: 908 DPGIPV------------HGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWW 952
Query: 711 SPSAPRCEETC-QHVRQSLQELPAGSRVEL----------VNTSCQDGYQLTGHAYQMCQ 759
S P C+ C VR + + E V+ + G Q H + + +
Sbjct: 953 SHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL-E 1011
Query: 760 D-------AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAE----------------- 795
D ENG + + PL ++ PP I G + A+
Sbjct: 1012 DHHDYLLITENGSFTQ--PLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNIT 1069
Query: 796 -----------------------NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
NF G+ +++ C G+ L G ++ C G WS
Sbjct: 1070 FSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGG--GRRVWS 1127
Query: 833 GPSPQCL 839
P P+C+
Sbjct: 1128 APLPRCV 1134
Score = 44.7 bits (104), Expect = 5e-04
Identities = 187/872 (21%), Positives = 282/872 (32%), Gaps = 178/872 (20%)
Query: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEKIINC-LSSGK--WSAVPP 208
ECP + N +N G S++ CE G++ G + I C L GK WS + P
Sbjct: 729 ECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIP 785
Query: 209 TCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM 268
C A C P+G + P G+ S C + +
Sbjct: 786 KCG-APCGGHFSAPSGVILSP---------------GWPGYYKDSLNCEWVIEAEPGHSI 829
Query: 269 PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE---EGVNFILIGESTLRC 325
+ E F + H G +L + GS Y P+ NFI L
Sbjct: 830 KITFERFQTELNYDVLEVHDGPNLLSPLLGS---YNGTQVPQFLFSSSNFIY-----LLF 881
Query: 326 TVDSQKTGTWSGPAPRCE-LSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGF 383
T D+ ++ +G E ++ + C P I + GR ++ TV F+C G+
Sbjct: 882 TTDNSRSN--NGFKIHYESVTVNTYSCLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGY 936
Query: 384 TLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
L + + C W P C+ C VR GT + +PGY
Sbjct: 937 RLSHEEPLLCEKNHWWSHPLPTCDALCGGD-------------VRGPSGTIL----SPGY 979
Query: 444 VLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY-KLS 502
S+ CT WT V K + + H ++ N S + +L+
Sbjct: 980 PEFYPNSLNCT----WTVDVTHGK--GVQFNFHTFHLEDHHDYLLITENGSFTQPLARLT 1033
Query: 503 GS---------VYQECQGTIPWFMEIRLCKE---IT--------CPPPPVIYNGAHTGSS 542
GS +Y + + + + + E IT C P + G+ G
Sbjct: 1034 GSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGF- 1092
Query: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
+F G T+T++C+ G + L G S I C R WS P P C +C
Sbjct: 1093 --NFGIGDTLTFSCSSG------YRLEGTSEIICLGGG--RRVWSAPLPRC-----VAEC 1137
Query: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
N + P Y + +C ++ I A + V +
Sbjct: 1138 GASATNNEGILLSPNYPLNYEN--NHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDG 1195
Query: 663 SPPGLH-HGRHTGGNTVFFVSGMTVDYT--------------CDPGYLLV--GNKSIHCM 705
H G TG + + G+T+ T D G+ LV + HC
Sbjct: 1196 KDKTTHLLGAFTGAS----MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCE 1251
Query: 706 PSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGI 765
P P+ + S Q AGS + C GY L G + C E
Sbjct: 1252 -----DPGIPQF-----GYKISDQGHFAGSTIIY---GCNPGYTLHGSSLLKCMTGERRA 1298
Query: 766 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAE---NFLYGNEV----SYECDQG-FYLLGEK 817
W +P C + C G+ +G + F Y N + E D G L
Sbjct: 1299 WDYPLPSC-IAECGGR---FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFL 1354
Query: 818 KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNP 877
+ W GP + ++ PE H LN + + Y+ +
Sbjct: 1355 AFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHS-TLNIVTIQFDTD--FYISKSG 1411
Query: 878 GFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILY 937
I S V D PGVP NG G PG ++++
Sbjct: 1412 FAIQFSSSVATACRD----PGVPM----------------NGTRNGDG---REPGDTVVF 1448
Query: 938 SCDQGYLLVGEALLLC---THEGTWSQPAPHC 966
CD GY L GE + C + W P C
Sbjct: 1449 QCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/251 (20%), Positives = 95/251 (37%), Gaps = 37/251 (14%)
Query: 606 HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKGC 661
+I NG ++ Y TVT+ C +G+ L+G S + C + W+ +P C C
Sbjct: 1602 NIMNGTRLG---MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPC 1658
Query: 662 QS----------PPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP---SG 708
S P G N V+ ++ + ++ G + S+H + G
Sbjct: 1659 GSRSTGSEGTVLSPNYPKNYSVGHNCVYSIA-VPKEFVVF-GQFVFFQTSLHDVVEVYDG 1716
Query: 709 NWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK 768
S+ + H +SL L +G+++ + TS +T + ++
Sbjct: 1717 PTQQSSLLSSLSGSHSGESL-PLSSGNQITIRFTSVG---PITAKGFHFV--------YQ 1764
Query: 769 KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGH 828
+P C P G+ G F G+ V ++C+ G+ L G ++C +
Sbjct: 1765 AVPRTSSTQCSSVPEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSL 1821
Query: 829 GSWSGPSPQCL 839
W+ P C+
Sbjct: 1822 AQWNDSLPTCI 1832
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 42/262 (16%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P NGK G +F G+ V + CD+ + L G K + C+ ++ +WS P
Sbjct: 382 CPDPGEPENGKRIG---SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
Query: 838 C--------LRSPPVTRCPNPEVKHGYKLNK----THSAYSHNDIVYVDCNPGFIMNGSR 885
C L+ P T +P Y N +A + N ++ ++ + G
Sbjct: 439 CKVKTCGSNLQGPSGT-FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYD 497
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLL 945
+ G P + + G P I S M + D+
Sbjct: 498 TLTIGDGGE--VGDPRTVLQVLTGSFVPDL----------IVSMSSQMWLHLQTDESVGS 545
Query: 946 VGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM 1005
VG + + KE+ S D G+ + V+ EC+ G+
Sbjct: 546 VGFKV--------------NYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFE 591
Query: 1006 LEGSPQSQCQSDHQWNPPLAVC 1027
L G CQ ++QW+ + +C
Sbjct: 592 LIGEKSIVCQENNQWSANIPIC 613
Score = 40.8 bits (94), Expect = 0.007
Identities = 66/299 (22%), Positives = 113/299 (37%), Gaps = 72/299 (24%)
Query: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM----WGPTRLP 144
SSC P VP + G T + GD + ++C T + ++G+ + C AN++ W +P
Sbjct: 176 SSCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASW-DFPVP 233
Query: 145 TC-----------VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
C S + P+ P + H+ ++ +I T S + EK
Sbjct: 234 ICRAEDACGGTMRGSSGIISSPSFP--NEYHNNADCTWTIVAEPGDTISLIFTDFQMEEK 291
Query: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL--RVGVTANFFCDEGYRLQG- 250
G + PPT + +G PPI+ + + +F D +R +G
Sbjct: 292 YDYLEIEG---SEPPTI----------WLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGF 338
Query: 251 -----------------------PPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH 287
S++ I +G T +C P P NG+
Sbjct: 339 SAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLC-----PDPGEPENGKR 393
Query: 288 IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
IG ++ S GS V ++CD D ++L G ++ C ++ WS P C++ T
Sbjct: 394 IG---SDFSLGSTVQFSCDED------YVLQGAKSITCQRIAEVFAAWSDHRPVCKVKT 443
Score = 40.4 bits (93), Expect = 0.009
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P P NG + VG I + C + LIG +L C+ V W+ P P+
Sbjct: 2119 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCL--HGVSRNWNHPLPR 2174
Query: 82 CE 83
CE
Sbjct: 2175 CE 2176
Score = 38.9 bits (89), Expect = 0.027
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 36/261 (13%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P I+NG + +G+ + Y C + L G +L CI D W++ P
Sbjct: 1596 SCFDPGNIMNG--TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1653
Query: 82 CEYFNKYSSCPEPIVPGGYKIRG------STPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
C P G + G S Y SV C + ++ V+ Q
Sbjct: 1654 CH------------APCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQF- 1700
Query: 136 NMWGPTRLPTCVSVF--PLECPALPMIHNGHHTSENVG-SIAPGLSVTYSCESGYLLVGE 192
++ T L V V+ P + +L +G H+ E++ S +++ ++ G
Sbjct: 1701 -VFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1759
Query: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPP 252
+ + AVP T +C S+ P + VG + F C+ GY L G
Sbjct: 1760 HFV-------YQAVPRT-SSTQCSSVPE-PRFGRRIGNEFAVGSSVLFDCNPGYILHGSI 1810
Query: 253 SSRCVIAGQGVA-WT-KMPVC 271
+ RC +A W +P C
Sbjct: 1811 AIRCETVPNSLAQWNDSLPTC 1831
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC----THEGTWSQPAPH 965
C P P G G RF G I YSC GY+L G L C + +W P P
Sbjct: 178 CGNPGVPPKGVLYG---TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
Query: 966 CK 967
C+
Sbjct: 235 CR 236
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P ++GR Y ++G+ + +SC +RL E+ LLC + + W P P
Sbjct: 905 SCLDPGIPVHGR--RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC----EKNHWWSHPLPT 958
Query: 82 CE 83
C+
Sbjct: 959 CD 960
Score = 35.8 bits (81), Expect = 0.23
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 6/49 (12%)
Query: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
+ G+ V+ C+ GY L C+ +H W+ PL C LCG
Sbjct: 922 FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTC------DALCG 964
Score = 35.8 bits (81), Expect = 0.23
Identities = 56/279 (20%), Positives = 105/279 (37%), Gaps = 63/279 (22%)
Query: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGP 140
F++Y+ C +P +P Y R + GD++TF+C + + + G + C +W
Sbjct: 1070 FSEYNLEPCEDPGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWS- 1127
Query: 141 TRLPTCVSVFPLEC-------------PALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
LP CV+ EC P P+ + +H + G + S + +
Sbjct: 1128 APLPRCVA----ECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFH 1183
Query: 188 LLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR 247
L G+ + + GK + LG F ++ G+T + ++ +
Sbjct: 1184 LAQGD--VLKIYDGK---------DKTTHLLGAFTGASMR-------GLTLSSTSNQLW- 1224
Query: 248 LQGPPSSRCVIAGQGVAWTKMPV--CEEIFCPSPPPILNGRHIGNSLANVSY--GSIVTY 303
L+ + G + +T + CE+ P G +++ + GS + Y
Sbjct: 1225 LEFNSDTEGTDEGFQLVYTSFELSHCEDPGIP---------QFGYKISDQGHFAGSTIIY 1275
Query: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRC 342
C+P + L G S L+C ++ W P P C
Sbjct: 1276 GCNP------GYTLHGSSLLKCMTGERR--AWDYPLPSC 1306
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH----QWNP 1022
+E+ SS + KG+ + G + C GY+L+G PQ C ++ W+
Sbjct: 171 EELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDF 230
Query: 1023 PLAVCRS 1029
P+ +CR+
Sbjct: 231 PVPICRA 237
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/73 (24%), Positives = 27/73 (36%), Gaps = 14/73 (19%)
Query: 522 CKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQ 581
C PP V+Y F G + Y+C G + L G + C +N
Sbjct: 178 CGNPGVPPKGVLYGTR--------FDVGDKIRYSCVTG------YILDGHPQLTCIANSV 223
Query: 582 ERGTWSGPAPLCK 594
+W P P+C+
Sbjct: 224 NTASWDFPVPICR 236
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 317 bits (811), Expect = 5e-86
Identities = 281/1002 (28%), Positives = 396/1002 (39%), Gaps = 116/1002 (11%)
Query: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW 131
D K K Y Y S P+ GG I T G V + CK + M G+ +
Sbjct: 2416 DHATSKKGFKIRYAAPYCSLTHPLKNGG--ILNRTAGAVGSKVHYFCKPGYRMVGHSNAT 2473
Query: 132 CQANNM----WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGY 187
C+ N + W + P C +V C NG T V Y C G+
Sbjct: 2474 CRRNPLGMYQWD-SLTPLCQAV---SCGIPESPGNGSFTGNE---FTLDSKVVYECHEGF 2526
Query: 188 LLVGEKIIN--CLSSGKWS--AVPPTCEEARCKSLG---------RFPNGKVKEPPILRV 234
L + C G WS PPTC+ C S+ R +G + E
Sbjct: 2527 KLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE-----Y 2581
Query: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
G C GY L+G RC G + P C I C S NG IG
Sbjct: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV- 2640
Query: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
YG+ +TC+ + L+G C + G WSG RC A C P
Sbjct: 2641 --YGATAIFTCN------TGYTLVGSHVRECLAN----GLWSGSETRC----LAGHCGSP 2684
Query: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP 413
+ +SG D ++Y DTV++ C GF L G+ C W PVC C P
Sbjct: 2685 DPIVNGHISG--DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
Query: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEA 473
N +G F+ + ++CN GY+L G QC S G W+ P+P C+V C
Sbjct: 2743 GNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
Query: 474 TG--RQLLTKPQHQFVRP-----DVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
G + Q F + C +G+ L GS C W + C I+
Sbjct: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAIS 2859
Query: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
C P V N TG E F YG V Y+C RG E SLIG T C QE W
Sbjct: 2860 CGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGNDTRVC----QEDSHW 2906
Query: 587 SGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKA 646
SG P C + A+G ++ + + F C G L+GS + C
Sbjct: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLGD---DFKTKSLLRFSCEMGHQLRGSPERTCLL 2963
Query: 647 DNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM 705
+ +W PVCE C +P +G + + F S +V Y C GY G + HC
Sbjct: 2964 NGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSS--SVIYACWEGYKTSGLMTRHCT 3021
Query: 706 PSGNWSPSAPRCE-ETCQHVRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDA 761
+G W+ +AP C +C + G+ + V+ C GY + +
Sbjct: 3022 ANGTWTGTAPDCTIISCGDPGTLANGIQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCT 3081
Query: 762 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 821
++G W P+CK + C PP + NG G +F +G+ +SY C G+ L L C
Sbjct: 3082 KDGRWNPSKPVCKAVLCPQPPPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSC 3138
Query: 822 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 881
+G G W G PQCL PV C +P + +L + ++++ V+ C FI+
Sbjct: 3139 ----EGRGVWKGEIPQCL---PVF-CGDPGIPAEGRL--SGKSFTYKSEVFFQCKSPFIL 3188
Query: 882 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG-GNIAR-FSPGMSILYSC 939
GS C D TW PTCI A C P P TP H G N +R + G ++ + C
Sbjct: 3189 VGSSRRVCQADGTWSGIQPTCIDPAHNTC-PDPGTP---HFGIQNSSRGYEVGSTVFFRC 3244
Query: 940 DQGYLLVGEALLLCTHEGTWS----QPAPH-CKEVNCSSPADMDGIQKGLEPRKMYQYGA 994
+GY + G C TWS + PH C++ + AD+ I + +G
Sbjct: 3245 RKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAID-------LPTFGY 3297
Query: 995 VVTLECEDGYMLE-GSPQSQCQSDHQWNPPLAVCRSRSLAPV 1035
+ C G+ L GS C++D +W VC+S+ + V
Sbjct: 3298 TLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCKSKGVREV 3339
Score = 308 bits (790), Expect = 1e-83
Identities = 273/1036 (26%), Positives = 424/1036 (40%), Gaps = 116/1036 (11%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C PP + + +G ++Y C + L+G L C ++ ++ P C
Sbjct: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQ--FEGSLPTC 2316
Query: 83 EYFNKYSSCPEPIV---PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
E + CP V G + P + +S T + N N +++ + +
Sbjct: 2317 E-----AQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFV---DTFQ 2368
Query: 140 PTRLPTCVSVF---PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
+ + VF + P L ++ H N S + L + +S + G KI
Sbjct: 2369 SEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKI-- 2426
Query: 197 CLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
+++A C NG + VG ++FC GYR+ G ++ C
Sbjct: 2427 -----RYAA-------PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATC 2474
Query: 257 VIAGQGV-AWTKM-PVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
G+ W + P+C+ + C P NG GN + S V Y C EG
Sbjct: 2475 RRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEF---TLDSKVVYEC----HEGFK 2527
Query: 315 FILIGESTLRCTVDSQKTGTWS--GPAPRCE-LSTSAVQCPHPQILRGRMVSGQKDRYTY 371
ES+ + T Q+ G WS G P C+ ++ +++ + + R+VSG + Y
Sbjct: 2528 L----ESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNE--Y 2581
Query: 372 NDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEK-ECQAPPNILNGQKEDRHMVR 428
V+ +C G+ L+G + +RC A GTW P C C + NG K V
Sbjct: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVY 2641
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQL---LTKPQHQ 485
G + ++CN GY LVG +C + G+W+ +C C + + ++
Sbjct: 2642 ---GATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFS 2698
Query: 486 FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLED 545
+ R V C G++L G+ + C W + +C ITC P N AH ++ +
Sbjct: 2699 Y-RDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPG---NPAHGFTNGSE 2754
Query: 546 FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
F V +TCN G + L G S +C SN G WS P P C++ V CS
Sbjct: 2755 FNLNDVVNFTCNTG------YLLQGVSRAQCRSN----GQWSSPLPTCRV----VNCSDP 2800
Query: 606 -HIANGYKISGKEAP--YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
+ N + + P + Y ++ + C GF L GSS + C A+ WD +P C
Sbjct: 2801 GFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISC 2860
Query: 663 SPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ 722
PG+ G F G V Y+C L+GN + C +WS + P C
Sbjct: 2861 GHPGVPANAVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNP 2918
Query: 723 HVRQSLQELPAGSRV-------ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
GSR+ L+ SC+ G+QL G + C NG W P+C+
Sbjct: 2919 GFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTC--LLNGSWSGLQPVCEA 2976
Query: 776 IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 835
+ C P NG + ++ L+ + V Y C +G+ G C + +G+W+G +
Sbjct: 2977 VSCGNPGTPTNGMI--VSSDGILFSSSVIYACWEGYKTSGLMTRHCTA----NGTWTGTA 3030
Query: 836 PQCLRSPPVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG--SRVIRCHTD 892
P C + C +P + +G + + ++ N V CNPG++M S IRC D
Sbjct: 3031 PDC----TIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPGYVMEAVTSATIRCTKD 3083
Query: 893 NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLL 952
W P P C KA + CP PP NG G + F G SI YSC GY L A+L
Sbjct: 3084 GRWNPSKPVC--KAVL-CPQPPPVQNGTVEGSD---FRWGSSISYSCMDGYQLSHSAILS 3137
Query: 953 CTHEGTWSQPAPHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQ 1011
C G W P C V C P GI +G K + Y + V +C+ ++L GS +
Sbjct: 3138 CEGRGVWKGEIPQCLPVFCGDP----GIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR 3193
Query: 1012 SQCQSDHQWNPPLAVC 1027
CQ+D W+ C
Sbjct: 3194 RVCQADGTWSGIQPTC 3209
Score = 196 bits (497), Expect = 1e-49
Identities = 147/512 (28%), Positives = 215/512 (41%), Gaps = 64/512 (12%)
Query: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIA 608
G+ V Y C PG + ++G S C N W PLC+ AV C
Sbjct: 2453 GSKVHYFCKPG------YRMVGHSNATCRRNPLGMYQWDSLTPLCQ----AVSCGIPESP 2502
Query: 609 NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR--CKADNTWDPE--IPVCEKGCQSP 664
+G E + + V ++C+ GF L+ S Q C+ D W + P C+
Sbjct: 2503 GNGSFTGNE--FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPS 2560
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDY------TCDPGYLLVGNKSIHCMPSGNWSPSAPRCE 718
H VSG +Y +C PGY L G + + C +G W+ R
Sbjct: 2561 IEAQLSEHVIWR---LVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDER-- 2615
Query: 719 ETCQHVR-QSLQELPAGSRVELVNT-------SCQDGYQLTGHAYQMCQDAENGIWFKKI 770
+C+ + SL P G+++ + +C GY L G + C NG+W
Sbjct: 2616 PSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNTGYTLVGSHVREC--LANGLWSGSE 2673
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
C HC P IVNG +G + F Y + V Y+C+ GF L+G C D K
Sbjct: 2674 TRCLAGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNPGFRLVGTSVRICLQDHK---- 2726
Query: 831 WSGPSPQCLRSPPVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC 889
WSG +P C+ P+T C +P HG+ S ++ ND+V CN G+++ G +C
Sbjct: 2727 WSGQTPVCV---PIT-CGHPGNPAHGFT---NGSEFNLNDVVNFTCNTGYLLQGVSRAQC 2779
Query: 890 HTDNTWVPGVPTCIKKAFIGCPPPPKTPNG-NHTGGNIAR-FSPGMSILYSCDQGYLLVG 947
++ W +PTC + C P N H N F GMSILY C +G+ L+G
Sbjct: 2780 RSNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLG 2836
Query: 948 EALLLCTHEGTWSQPAPHCKEVNCSSP-ADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 1006
+ L C G W + P C ++C P + + G +++ YGAVV C L
Sbjct: 2837 SSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLTG----ELFTYGAVVHYSCRGSESL 2892
Query: 1007 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
G+ CQ D W+ L C + P CG
Sbjct: 2893 IGNDTRVCQEDSHWSGALPHCTGNN--PGFCG 2922
Score = 195 bits (496), Expect = 2e-49
Identities = 155/562 (27%), Positives = 229/562 (40%), Gaps = 61/562 (10%)
Query: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIR 103
G I Y C F L+G +L C+ +G WD+ PKC SC P VP +
Sbjct: 2821 GMSILYHCKKGFYLLGSSALTCMA----NGLWDRSLPKCLAI----SCGHPGVPANAVLT 2872
Query: 104 GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLEC--PALPMIH 161
G + +G V ++C+ + S+ GN + CQ ++ W LP C P C P P
Sbjct: 2873 GEL-FTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGA-LPHCTGNNPGFCGDPGTPA-- 2928
Query: 162 NGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRF 221
H S + +SCE G+ L G CL +G WS + P CE C + G
Sbjct: 2929 ---HGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTP 2985
Query: 222 PNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPP 280
NG + + + + C EGY+ G + C G WT P C I C P
Sbjct: 2986 TNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANG---TWTGTAPDCTIISCGDPG 3042
Query: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
+ NG G + ++ V+Y C+P G + +T+RCT K G W+ P
Sbjct: 3043 TLANGIQFG---TDFTFNKTVSYQCNP----GYVMEAVTSATIRCT----KDGRWNPSKP 3091
Query: 341 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWE 400
C+ AV CP P ++ V G + + ++ ++CM G+ L S + C +G W+
Sbjct: 3092 VCK----AVLCPQPPPVQNGTVEGSD--FRWGSSISYSCMDGYQLSHSAILSCEGRGVWK 3145
Query: 401 PSAPVCEKECQAPPNI-LNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
P C P I G+ + F + + + C ++LVG C ++G W
Sbjct: 3146 GEIPQCLPVFCGDPGIPAEGRLSGK---SFTYKSEVFFQCKSPFILVGSSRRVCQADGTW 3202
Query: 460 TPPVPQCKVAA---CEATGRQ---LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTI 513
+ P C A C G + + V V C +GY + GS + C +
Sbjct: 3203 SGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANL 3262
Query: 514 PWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP-YGTTVTYTCNPGPERGVEFSLIGES 572
W C C P AH D P +G T+ YTC+PG F L G S
Sbjct: 3263 TWSGIQTECIPHACRQPE---TPAHADVRAIDLPTFGYTLVYTCHPG------FFLAGGS 3313
Query: 573 TIRCTSNDQERGTWSGPAPLCK 594
R D + W+G +P+CK
Sbjct: 3314 EHRTCKADMK---WTGKSPVCK 3332
Score = 172 bits (435), Expect = 2e-42
Identities = 175/658 (26%), Positives = 267/658 (40%), Gaps = 97/658 (14%)
Query: 408 KECQAPPNILNGQK--EDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC--TSEGVWTPPV 463
K+CQ PP + + ED F+ G +KY C+PGY LVG + + C +S+ + +
Sbjct: 2257 KKCQPPPAVPQAEMLTEDDD---FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSL 2313
Query: 464 PQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFME-IRLC 522
P C+ A C A ++ T + P + S S+ E I F++ +
Sbjct: 2314 PTCE-AQCPA--NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
Query: 523 KEITC----------PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
K+ P V+ +G HT S +F + Y + S
Sbjct: 2371 KQFDALEVFDGSSGQSPLLVVLSGNHTEQS--NFTSRSNQLY--------------LRWS 2414
Query: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS 632
T TS ++G K+ A CS H I + A V + C
Sbjct: 2415 TDHATS---KKG--------FKIRYAAPYCSLTHPLKNGGILNRTAG-AVGSKVHYFCKP 2462
Query: 633 GFTLKGSSQIRCKAD----NTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVD 687
G+ + G S C+ + WD P+C+ C P +G TG F V
Sbjct: 2463 GYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVV 2519
Query: 688 YTCDPGYLLVGNK--SIHCMPSGNWSPSA--PRCEE-TCQHVRQSLQE-----LPAGSRV 737
Y C G+ L ++ + C G WS P C+ C + L E L +GS
Sbjct: 2520 YECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
Query: 738 EL---VNTSCQDGYQLTGHAYQMCQDAENGIW--FKKIPLCKVIHCHPPPVIVNGKHTGM 792
E V SC GY L G CQ NG W + P C+VI C NG G
Sbjct: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQ--ANGTWNIGDERPSCRVISCGSLSFPPNGNKIGT 2637
Query: 793 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE- 851
+ +YG + C+ G+ L+G +C + +G WSG +CL C +P+
Sbjct: 2638 LT---VYGATAIFTCNTGYTLVGSHVRECLA----NGLWSGSETRCLAG----HCGSPDP 2686
Query: 852 VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCP 911
+ +G+ + +S+ D V CNPGF + G+ V C D+ W P C+ I C
Sbjct: 2687 IVNGH---ISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVP---ITCG 2740
Query: 912 PPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNC 971
P +G G + F+ + ++C+ GYLL G + C G WS P P C+ VNC
Sbjct: 2741 HPGNPAHGFTNG---SEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNC 2797
Query: 972 SSPADMD-GIQKGLEP-RKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 1027
S P ++ I+ G + + ++YG + C+ G+ L GS C ++ W+ L C
Sbjct: 2798 SDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKC 2855
Score = 96.7 bits (239), Expect = 1e-19
Identities = 87/336 (25%), Positives = 138/336 (41%), Gaps = 40/336 (11%)
Query: 15 APGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGT 74
AP ISCG P + NG + T + Y C+ + + E + DG
Sbjct: 3030 APDCTIISCGDPGTLANG--IQFGTDFTFNKTVSYQCNPGY--VMEAVTSATIRCTKDGR 3085
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQA 134
W+ P C K CP+P + GS +R G S++++C + ++ + + C+
Sbjct: 3086 WNPSKPVC----KAVLCPQPPPVQNGTVEGS-DFRWGSSISYSCMDGYQLSHSAILSCEG 3140
Query: 135 NNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI 194
+W +P C+ VF + P +P G + + S V + C+S ++LVG
Sbjct: 3141 RGVW-KGEIPQCLPVFCGD-PGIPA--EGRLSGK---SFTYKSEVFFQCKSPFILVGSSR 3193
Query: 195 INCLSSGKWSAVPPTCEEA---RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
C + G WS + PTC + C G G VG T F C +GY +QG
Sbjct: 3194 RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGS 3253
Query: 252 PSSRCV--IAGQGVAWTKMP-VCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPD 308
+ C+ + G+ +P C + P P + R I ++G + YTC P
Sbjct: 3254 TTRTCLANLTWSGIQTECIPHACRQ---PETPAHADVRAIDLP----TFGYTLVYTCHP- 3305
Query: 309 PEEGVNFILIGESTLR-CTVDSQKTGTWSGPAPRCE 343
F L G S R C D + W+G +P C+
Sbjct: 3306 -----GFFLAGGSEHRTCKADMK----WTGKSPVCK 3332
Score = 82.4 bits (202), Expect = 2e-15
Identities = 149/671 (22%), Positives = 236/671 (35%), Gaps = 140/671 (20%)
Query: 409 ECQAP--PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTS--EGVWTPPVP 464
+C+ P PN +++ H T + YSCNPGY + G ++ C S VW P+P
Sbjct: 1217 KCEDPGIPNYGYRIRDEGHFT----DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLP 1272
Query: 465 QCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWF-------M 517
C +A C G Q+ + + P + + + + TI M
Sbjct: 1273 SC-IAEC---GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEM 1328
Query: 518 EIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVE---FSLIGESTI 574
+ K P I +GS+L + + T + T + + FS+ ++I
Sbjct: 1329 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSI 1388
Query: 575 RCTSNDQ---ERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCY 631
T ND + GT G + +EA DTVTF+C
Sbjct: 1389 AATCNDPGMPQNGTRYGDS-------------------------REA----GDTVTFQCD 1419
Query: 632 SGFTLKGSSQIRCKADNT---WDPEIPVCEKGCQS------------------PPGLHHG 670
G+ L+G ++I C N W P+ P C C PPG
Sbjct: 1420 PGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYPQPYPPGKECD 1479
Query: 671 RHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQE 730
N F ++ + + +P Y +H E++ + S Q
Sbjct: 1480 WRVKVNPDFVIALIFKSFNMEPSY-----DFLHIYEG----------EDSNSPLIGSYQG 1524
Query: 731 LPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENG-----IWFKKIPLCKVIHCHPPPVIV 785
A R+E S ++ DA G I FK+ P C P I+
Sbjct: 1525 SQAPERIESSGNSLFLAFR---------SDASVGLSGFAIEFKEKPREA---CFDPGNIM 1572
Query: 786 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
NG G +F G+ ++Y+CD G+ +L + C + G SW P C +P
Sbjct: 1573 NGTRVGT---DFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC-NAPCGG 1628
Query: 846 RCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKK 905
+ E G L+ Y HN C + V+ + + +
Sbjct: 1629 QYTGSE---GVVLSPN---YPHNYTAGQICLYSITVPKEFVV--FGQFAYFQTALNDLAE 1680
Query: 906 AFIGCPPPPK---TPNGNHTGGNIARFSPGMSIL-YSCDQGYLLVGEALLLCTHEGTWSQ 961
F G + + +G+H+G + + +L +S G G + Q
Sbjct: 1681 LFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVY--------Q 1732
Query: 962 PAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSD--- 1017
P + CSS P G + G E + G++V EC GY+L+GS CQS
Sbjct: 1733 AVPRTSDTQCSSVPEPRYGRRIGSE----FSAGSIVRFECNPGYLLQGSTALHCQSVPNA 1788
Query: 1018 -HQWNPPLAVC 1027
QWN + C
Sbjct: 1789 LAQWNDTIPSC 1799
Score = 74.7 bits (182), Expect = 4e-13
Identities = 140/663 (21%), Positives = 229/663 (34%), Gaps = 123/663 (18%)
Query: 215 CKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEI 274
C G NG + ++G T + CD GY++ P S CVI G P +++
Sbjct: 1565 CFDPGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADG-----KPSWDQV 1618
Query: 275 FCPSPPPILNGRHIG--------NSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326
PS G++ G N N + G I Y+ E F++ G+ T
Sbjct: 1619 L-PSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKE----FVVFGQFAYFQT 1673
Query: 327 VDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK 386
+ + G + L +S +SG +T+ A L+
Sbjct: 1674 ALNDLAELFDGTHAQARLLSS--------------LSGSHS----GETLPLATSNQILLR 1715
Query: 387 GSKQIRCNAQG---TWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
S + +A+G ++ + +C + P G++ F G+ +++ CNPGY
Sbjct: 1716 FSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSE---FSAGSIVRFECNPGY 1772
Query: 444 VLVGEESIQCTSE----GVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGY 499
+L G ++ C S W +P C V C T+ + + P G
Sbjct: 1773 LLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGN----FTQRRGTILSPGYPEPYGNNL 1827
Query: 500 KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPG 559
+ +G+ I E + G T L F GTTV N
Sbjct: 1828 NCIWKII-VTEGSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFS-GTTVPALLN-S 1884
Query: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
+ + ++ E T + L A Q +N KI +
Sbjct: 1885 TSNQLYLHFQSDISVAAAGFHLEYKT---------VGLAACQ-EPALPSNSIKIGDR--- 1931
Query: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADNT--WDPEIPVCEKGCQSPPGLHHGRHTGGNT 677
Y ND ++F+C G+TL+G S I C W+ P+C C G T
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATC-------------GGT 1978
Query: 678 VFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAP----------RCEETCQHVRQS 727
+ + G+ + PG+ ++ C W S P H
Sbjct: 1979 LSTLGGVIL----SPGFPGSYPNNLDC----TWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Query: 728 LQELP--------AGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFK-KIPLCKVIHC 778
+Q P S +L ++ H Y ++N FK ++ +C
Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYS--DHSQNRQGFKLAYQAYELQNC 2088
Query: 779 HPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHG---SWSGPS 835
PP NG M+ ++ G VS+EC G+ L+G L C+ HG +W+ P
Sbjct: 2089 PDPPPFQNGY---MINSDYSVGQSVSFECYPGYILIGHPVLTCQ-----HGINRNWNYPF 2140
Query: 836 PQC 838
P+C
Sbjct: 2141 PRC 2143
Score = 66.2 bits (160), Expect = 2e-10
Identities = 173/830 (20%), Positives = 273/830 (32%), Gaps = 142/830 (17%)
Query: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
F++Y C +P VP + R + GDS+TF+C + + G + C +W
Sbjct: 1038 FSEYDLEPCDDPGVPA-FSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSA 1096
Query: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
LP CV+ L P P ++ +H G + S L G
Sbjct: 1097 P-LPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEG 1155
Query: 192 EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNG--------------------------- 224
+ + + GK S+ P + + LG N
Sbjct: 1156 DTLK--VYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSF 1213
Query: 225 ---KVKEPPILRVGVTAN-----------FFCDEGYRLQGPPSSRCVIAGQGVAWTK-MP 269
K ++P I G + C+ GY + G + C ++G W K +P
Sbjct: 1214 DLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLP 1272
Query: 270 VCEEIFCPSPPPILNGRHIGNSL-ANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
C +GR + A T+ + DP + ++ I T D
Sbjct: 1273 SCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDT-EMAHD 1331
Query: 329 SQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGS 388
K W GP L P+ + S D+ F GF+++ S
Sbjct: 1332 ILKV--WDGPVDSDILLKEWSGSALPEDIHSTFNS----LTLQFDSDFFISKSGFSIQFS 1385
Query: 389 KQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGE 448
I +P P Q R+ + G ++ + C+PGY L G+
Sbjct: 1386 TSIAATCN---DPGMP---------------QNGTRYGDSREAGDTVTFQCDPGYQLQGQ 1427
Query: 449 ESIQC---TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSV 505
I C + W P P C +AAC LT P + P+ G
Sbjct: 1428 AKITCVQLNNRFFWQPDPPTC-IAACGGN----LTGPAGVILSPNYPQPYPPG------- 1475
Query: 506 YQECQGTI---PWFMEIRLCKEITCPPP---PVIYNGAHTGSSLEDFPYGTTVTYTCNPG 559
+EC + P F+ + K P IY G + S L +Y +
Sbjct: 1476 -KECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPL-------IGSYQGSQA 1527
Query: 560 PERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAP 619
PER +E S G S +D G SG A K +I NG ++
Sbjct: 1528 PER-IESS--GNSLFLAFRSDASVGL-SGFAIEFKEKPREACFDPGNIMNGTRVG---TD 1580
Query: 620 YFYNDTVTFKCYSGFTLKGSSQIRC--KADN--TWDPEIPVCEKGCQSPPGLHHGRHTGG 675
+ T+T++C SG+ + S I C AD +WD +P C C G++TG
Sbjct: 1581 FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPC-------GGQYTGS 1633
Query: 676 NTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ-----HVRQSLQE 730
V +YT L + G ++ + + H + L
Sbjct: 1634 EGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLS 1693
Query: 731 LPAGSRV-ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
+GS E + + + L A ++ +P C P G+
Sbjct: 1694 SLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSDTQCSSVPEPRYGRR 1753
Query: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
G F G+ V +EC+ G+ L G L C+S W+ P C+
Sbjct: 1754 IG---SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV 1800
Score = 63.5 bits (153), Expect = 1e-09
Identities = 94/457 (20%), Positives = 151/457 (33%), Gaps = 83/457 (18%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
+CG+P IL G + + T +G IRYSC + L G L CI +WD PAP
Sbjct: 144 TCGNPGEILKGVL--HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
Query: 82 CE--------YFNKYSSCPEPIVPGGYKIRGSTPY----RHGDSVTFACKTNFSMNGN-- 127
C SS P P Y+ + GD++ T+F +
Sbjct: 202 CRAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVF-TDFQLEEGYD 260
Query: 128 ---------KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLS 178
S+W N+ P + L + +H + +
Sbjct: 261 FLEISGTEAPSIWLTGMNLPSPV-------ISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Query: 179 VTYSCESGYLLV----GEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
G ++ G + LS G + V C + G NG+ RV
Sbjct: 314 AIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDP-----GIPENGRRAGSDFSRV 368
Query: 235 GVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGRHI 288
G F C++ Y LQG S C + AW+ P+C C S P ++ +
Sbjct: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY 428
Query: 289 GNSLANVSYGSIVTYTCDPDP-----------EEGVNFILIGE----------------S 321
+ ++ V T DPD E G + + +G+ S
Sbjct: 429 PVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGS 488
Query: 322 TLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRM------VSGQK--DRYTYND 373
++ + S W + + + + +I +G G++ + + D
Sbjct: 489 SVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGD 548
Query: 374 TVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
T+ F C F L G + I C W + P C C
Sbjct: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
Score = 63.5 bits (153), Expect = 1e-09
Identities = 108/506 (21%), Positives = 178/506 (35%), Gaps = 96/506 (18%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT----SEGVWTPPVPQ 465
C P IL G H RF+ G I+YSC PGY+L G + C + W P P
Sbjct: 145 CGNPGEILKGVL---HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPF 201
Query: 466 CKV-AACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPW-FMEIRLCK 523
C+ AC T L P S + ++ E TI F + +L +
Sbjct: 202 CRAEGACGGT----LRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE 257
Query: 524 -----EITCPPPPVIY-NGAHTGSSLEDFPYGTTVTYTCNPGPER-----------GVEF 566
EI+ P I+ G + S + + +T + R +E
Sbjct: 258 GYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
Query: 567 SLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTV 626
G + + S ++L++ C I + +G + V
Sbjct: 318 KSRGVKMLPSKDGSHKNSVLSQGG----VALVSDMCPDPGIPENGRRAGSDFSRV-GANV 372
Query: 627 TFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVS 682
F C + L+GS I C+ W P+C T G+ + S
Sbjct: 373 QFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRA------------RTCGSNLRGPS 420
Query: 683 GMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNT 742
G+ P Y + + HC+ W + ++ + + EL G V
Sbjct: 421 GVITS----PNYPVQYEDNAHCV----WVITTTDPDKVIKLAFEEF-ELERGYDTLTVGD 471
Query: 743 SCQDG------YQLTGHAY-QMCQDAENGIWFKK-------IPLCKVIH-------CHPP 781
+ + G Y LTG + + N +W P K ++ C P
Sbjct: 472 AGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDP 531
Query: 782 PVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL-- 839
+ GK TG +FL+G+ +++EC F L+GE+ + C+ +++ WSG P C+
Sbjct: 532 GIPAYGKRTG---SSFLHGDTLTFECPAAFELVGERVITCQQNNQ----WSGNKPSCVFS 584
Query: 840 ------RSPPVTRCPNPEVKHGYKLN 859
S + PN ++G +N
Sbjct: 585 CFFNFTASSGIILSPNYPEEYGNNMN 610
Score = 62.0 bits (149), Expect = 3e-09
Identities = 151/692 (21%), Positives = 223/692 (32%), Gaps = 171/692 (24%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT----SEGVWTPPVPQ 465
C P NG++ R G ++++SC YVL G +SI C + W+ P
Sbjct: 349 CPDPGIPENGRRAGSDFSRV--GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPI 406
Query: 466 CKVAACEATGRQ---LLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLC 522
C+ C + R ++T P + V+ + N+ C W
Sbjct: 407 CRARTCGSNLRGPSGVITSPNYP-VQYEDNAHC------------------VWV------ 441
Query: 523 KEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGEST---IRCTSN 579
IT P + A LE TV G R V + L G S I SN
Sbjct: 442 --ITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSN 499
Query: 580 DQERGTWSGPA---PLCKLSLLAVQ---CSHVHIANGYKISGKEAPYFYNDTVTFKCYSG 633
S + P K ++ C I K +G + + DT+TF+C +
Sbjct: 500 QMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSS--FLHGDTLTFECPAA 557
Query: 634 FTLKGSSQIRCKADNTWDPEIPVC----------EKGCQSPPGLHHGRHTGGNTVFFV-- 681
F L G I C+ +N W P C G P N V+ +
Sbjct: 558 FELVGERVITCQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIIS 617
Query: 682 -SGMTV-----DYTCDP--GYLLVGNKSIHCMP-----SGNWSPSAPRCEETCQHVRQSL 728
G + D+ +P +L V + I + SGN PS
Sbjct: 618 EPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-------------- 663
Query: 729 QELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA--ENGIWFKKIPLCKVIHCHPPPVIVN 786
S +V Q + TG + + +N CH P + +N
Sbjct: 664 ----LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQN-------------ECHDPGIPIN 706
Query: 787 GKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
G+ G + FL G+ VS+ CD GF G + + C G+ WS P
Sbjct: 707 GRRFG---DRFLLGSSVSFHCDDGFVKTQGSESITCILQD-GNVVWSSTVP--------- 753
Query: 846 RCPNPEVKH--------------GYKLNKTHSAYSHNDIVYVDCNPGF---IMNGSRVIR 888
RC P H GY + H + ++ PG I
Sbjct: 754 RCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEW------IIEAKPGHSIKITFDRFQTE 807
Query: 889 CHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGE 948
+ D V P IG + P + GN M +L++ D +G
Sbjct: 808 VNYDTLEVRDGPAS-SSPLIGEYHGTQAPQFLISTGNF------MYLLFTTDNSRSSIGF 860
Query: 949 ALLLCTHEGTWSQPAPHCKEVNCSSPADMD-GIQ-KGLEPRKMYQYGAVVTLECEDGYML 1006
+ H + V S + +D GI G + + VT C+ GY L
Sbjct: 861 LI--------------HYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTL 906
Query: 1007 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
C+ +HQWN L C LCG
Sbjct: 907 SDDEPLVCERNHQWNHALPSC------DALCG 932
Score = 59.7 bits (143), Expect = 1e-08
Identities = 135/643 (20%), Positives = 221/643 (34%), Gaps = 134/643 (20%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
+C P I+NG + T +G+ I Y C ++++ S+ C+ +WD+ P
Sbjct: 1564 ACFDPGNIMNG--TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPS 1621
Query: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
C + C G + S Y H + C +S+ K + T
Sbjct: 1622 CN-----APCGGQYT-GSEGVVLSPNYPHNYTAGQICL--YSITVPKEFVVFGQFAYFQT 1673
Query: 142 RLPTCVSVFPLECPALPMIH--NGHHTSENVG-SIAPGLSVTYSCESGYLLVGEKIINCL 198
L +F ++ +G H+ E + + + + + +S +SG G +
Sbjct: 1674 ALNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFV--- 1730
Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
+ AVP T + +C S+ G+ + G F C+ GY LQG + C
Sbjct: 1731 ----YQAVPRT-SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTALHCQS 1784
Query: 259 AGQGVA-WTK-----MPVCEEIFCPSPPPILNGRH---IGNSLANVSYGSIVTYTCDPDP 309
+A W + C F IL+ + GN+L N + IVT
Sbjct: 1785 VPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNL-NCIWKIIVT------E 1837
Query: 310 EEGVNFILIGESTLR----------CTVDSQKTGTWSGPAPRCELSTSAVQ--------- 350
G+ +I +T + V + + G++SG L++++ Q
Sbjct: 1838 GSGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDI 1897
Query: 351 ------------------CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIR 392
C P + + G DRY ND + F C G+TL+G I
Sbjct: 1898 SVAAAGFHLEYKTVGLAACQEPALPSNSIKIG--DRYMVNDVLSFQCEPGYTLQGRSHIS 1955
Query: 393 CNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
C GT W +P+C C + L G V PG Y N
Sbjct: 1956 C-MPGTVRRWNYPSPLCIATCGGTLSTLGG-------VILSPGFPGSYPNN--------- 1998
Query: 450 SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD-----VNSSCGE--GYKLS 502
+ CT W +P A + T+ H F+ + G+ G L
Sbjct: 1999 -LDCT----WRISLPIGYGAHIQFL--NFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLP 2051
Query: 503 GSVYQECQGTIPWF------------MEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGT 550
++ T+ F + + + CP PP NG S D+ G
Sbjct: 2052 AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYMINS---DYSVGQ 2108
Query: 551 TVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC 593
+V++ C PG + LIG + C W+ P P C
Sbjct: 2109 SVSFECYPG------YILIGHPVLTCQHGINR--NWNYPFPRC 2143
Score = 54.3 bits (129), Expect = 6e-07
Identities = 108/480 (22%), Positives = 164/480 (34%), Gaps = 86/480 (17%)
Query: 165 HTSENVGSIAPGL----------SVTYSCESGYLLVGEKIINCLSS----GKWSAVPPTC 210
HT N G I G+ + YSC GY+L G I+ C+ S W P C
Sbjct: 143 HTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
Query: 211 E-EARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
E C R + + P N C + + P + +
Sbjct: 203 RAEGACGGTLRGTSSSISS-PHFPSEYENNADCT--WTILAEPGDTIALVFTDFQLEEGY 259
Query: 270 VCEEIFCPSPPPI-LNGRHIGNSLANVSYGSIVTYTCDPDPE-EGVNFILIGESTLRCTV 327
EI P I L G ++ + + + + +T D + +G N + ++ +
Sbjct: 260 DFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFN----AQFQVKKAI 315
Query: 328 DSQKTG-----TWSGPAPRCELSTSAV-----QCPHPQILR-GRMVSGQKDRYTYNDTVI 376
+ + G + G LS V CP P I GR R N V
Sbjct: 316 ELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGAN--VQ 373
Query: 377 FACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE-----KECQAPPNILNG-----QKE 422
F+C + L+GSK I C W P+C + P ++ Q E
Sbjct: 374 FSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYE 433
Query: 423 DR-HMV----RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQ 477
D H V DP IK + + G +++ G V +
Sbjct: 434 DNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDL 493
Query: 478 LLTKPQHQFVRPDVNSSCGE-GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
+++ ++ + S G G+K +VYQE + + C P + G
Sbjct: 494 IVSMSNQMWLHLQSDDSIGSPGFK---AVYQEIE-------------KGGCGDPGIPAYG 537
Query: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLS 596
TGSS F +G T+T+ C F L+GE I C N+Q WSG P C S
Sbjct: 538 KRTGSS---FLHGDTLTFECPAA------FELVGERVITCQQNNQ----WSGNKPSCVFS 584
Score = 54.3 bits (129), Expect = 6e-07
Identities = 98/448 (21%), Positives = 156/448 (34%), Gaps = 102/448 (22%)
Query: 659 KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMP--SGNWSPSAPR 716
+ C PP +G + + G +V + C PGY+L+G+ + C + NW+ PR
Sbjct: 2086 QNCPDPPPFQNGYMINSD---YSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPR 2142
Query: 717 CEETCQHVRQS----------------------LQELPAGSRV---------ELVN---- 741
C+ C + S L +P G V E VN
Sbjct: 2143 CDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIA 2202
Query: 742 ------------------TSCQDGYQLTGHA-YQMCQDAENGIWF-KKIPLCKVIHCHPP 781
T+ + Y T + D NG +F ++ C PP
Sbjct: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPP 2262
Query: 782 PVIVNGKHTGMMAE--NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
P + + M+ E +F G+ V Y+C G+ L+G L C+ S+ + G P C
Sbjct: 2263 PAVPQAE---MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQ--LQFEGSLPTC- 2316
Query: 840 RSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGV 899
+CP EV+ G Y N C+ + + I D T+
Sbjct: 2317 ----EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVD-TFQSEK 2371
Query: 900 PTCIKKAFIGC---PPPPKTPNGNHT-GGNIARFSPGMSILYSCDQGYLLVGEALLLCTH 955
+ F G P +GNHT N S + + +S D G +
Sbjct: 2372 QFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKI----- 2426
Query: 956 EGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 1015
AP+C + + P GI R G+ V C+ GY + G + C+
Sbjct: 2427 ----RYAAPYC---SLTHPLKNGGILN----RTAGAVGSKVHYFCKPGYRMVGHSNATCR 2475
Query: 1016 SD----HQWNPPLAVCRSRSLAPVLCGI 1039
+ +QW+ +C++ V CGI
Sbjct: 2476 RNPLGMYQWDSLTPLCQA-----VSCGI 2498
Score = 44.7 bits (104), Expect = 5e-04
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 89/445 (20%)
Query: 487 VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
+R V SC GY LS C+ W + C + C +G DF
Sbjct: 892 IRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSPGFPDF 950
Query: 547 -PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQ----ERGTWSGPAPLCKLSLLAVQ 601
P T+T +GV+ +I + +S+D E G++S P S+L
Sbjct: 951 YPNSLNCTWTIEVSHGKGVQ--MIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLP-- 1006
Query: 602 CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC 661
H A + + + + +++ Y GF + S D DP +P +
Sbjct: 1007 --HTIKAGLFGNFTAQLRFISDFSIS---YEGFNITFSEYDLEPCD---DPGVPAFSRRI 1058
Query: 662 QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN--WSPSAPRCEE 719
G H G G ++ ++C GY L G + C+ G WS PRC
Sbjct: 1059 ----GFHFG-----------VGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVA 1103
Query: 720 TCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHA-YQMCQDAENGIWFK---------- 768
C + G+ L++ + Y Y++ +A GI +
Sbjct: 1104 ECGASVK-------GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGD 1156
Query: 769 --KIPLCKVIHCHPPPVIVNGKHTGMMAEN-----FLYGNEVSYECDQGFYLLGEKKLQC 821
K+ K P + G++ + +L N + DQGF L
Sbjct: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLT------- 1209
Query: 822 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFI 880
S + +C +P + +GY++ + + +V CNPG+
Sbjct: 1210 -----------------YTSFDLVKCEDPGIPNYGYRIRD--EGHFTDTVVLYSCNPGYA 1250
Query: 881 MNGSRVIRCHTDN--TWVPGVPTCI 903
M+GS + C + + W +P+CI
Sbjct: 1251 MHGSNTLTCLSGDRRVWDKPLPSCI 1275
Score = 43.5 bits (101), Expect = 0.001
Identities = 100/481 (20%), Positives = 171/481 (35%), Gaps = 79/481 (16%)
Query: 1 MGAAGLLGVFLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGE 60
+G+ G V+ + G CG P G+ + + G + + C F L+GE
Sbjct: 511 IGSPGFKAVYQEIEKGG-----CGDPGIPAYGKRT--GSSFLHGDTLTFECPAAFELVGE 563
Query: 61 KSLLCITKDKVDGTWDKPAPKCEY---FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFA 117
+ + C + + W P C + FN +S G + + P +G
Sbjct: 564 RVITC----QQNNQWSGNKPSCVFSCFFNFTAS-------SGIILSPNYPEEYG------ 606
Query: 118 CKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLE--CPALPMIHNGHHTSENVGSIAP 175
N VW + +R+ + F +E L + +G +G+ +
Sbjct: 607 -------NNMNCVWLIISEPG--SRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSG 657
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGK-WSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
+ SG+++ E + ++G+ ++ T + C G NG+ L +
Sbjct: 658 NEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFL-L 716
Query: 235 GVTANFFCDEGY-RLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSL 292
G + +F CD+G+ + QG S C++ V W+ +P CE P G H+ S
Sbjct: 717 GSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCE---APC------GGHLTASS 767
Query: 293 ANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGT-------WSGPAPRCELS 345
+ Y D E + G S ++ T D +T GPA L
Sbjct: 768 GVILPPGWPGYYKDSLHCEWIIEAKPGHS-IKITFDRFQTEVNYDTLEVRDGPASSSPLI 826
Query: 346 TSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPV 405
PQ L +S Y T GF + + + + +P PV
Sbjct: 827 GEYHGTQAPQFL----ISTGNFMYLLFTTDNSRSSIGFLIH-YESVTLESDSCLDPGIPV 881
Query: 406 CEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQ 465
NG RH F +++ +SC+PGY L +E + C W +P
Sbjct: 882 ------------NGH---RHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPS 926
Query: 466 C 466
C
Sbjct: 927 C 927
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
CP PPP NG I ++ S G V++ C P +ILIG L C + W
Sbjct: 2088 CPDPPPFQNGYMIN---SDYSVGQSVSFECYP------GYILIGHPVLTCQHGINR--NW 2136
Query: 336 SGPAPRCE 343
+ P PRC+
Sbjct: 2137 NYPFPRCD 2144
Score = 39.7 bits (91), Expect = 0.016
Identities = 52/230 (22%), Positives = 86/230 (37%), Gaps = 28/230 (12%)
Query: 45 TVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC--EYFNK-YSSCPEPIVPGGYK 101
TV+ YSC+ + + G +L C++ D+ WDKP P C E + +++ I+ GY
Sbjct: 1239 TVVLYSCNPGYAMHGSNTLTCLSGDR--RVWDKPLPSCIAECGGQIHAATSGRILSPGY- 1295
Query: 102 IRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF--PLECPALPM 159
PY + C + K++ ++ + V+ P++ L
Sbjct: 1296 ---PAPYDN----NLHCTWIIEADPGKTISLHF-IVFDTEMAHDILKVWDGPVDSDILLK 1347
Query: 160 IHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLG 219
+G E++ S L++ + + +S +S T A C G
Sbjct: 1348 EWSGSALPEDIHSTFNSLTLQFDSDF-----------FISKSGFSIQFSTSIAATCNDPG 1396
Query: 220 RFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP 269
NG + G T F CD GY+LQG CV W P
Sbjct: 1397 MPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
Score = 39.3 bits (90), Expect = 0.021
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 928 RFSPGMSILYSCDQGYLLVGEALLLCT----HEGTWSQPAPHCK 967
RF+ G I YSC GY+L G A+L C + +W PAP C+
Sbjct: 160 RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
Score = 39.3 bits (90), Expect = 0.021
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query: 845 TRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT----WVPGV 899
T+C + PE ++G ++ S +S IV +CNPG+++ GS + C + W +
Sbjct: 1740 TQCSSVPEPRYGRRIG---SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
Query: 900 PTCI 903
P+C+
Sbjct: 1797 PSCV 1800
Score = 38.5 bits (88), Expect = 0.035
Identities = 56/259 (21%), Positives = 86/259 (33%), Gaps = 71/259 (27%)
Query: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLS--SGKWSAVPPTCE 211
CP P NG+ + + + G SV++ C GY+L+G ++ C + W+ P C
Sbjct: 2088 CPDPPPFQNGYMINSDY---SVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC- 2143
Query: 212 EARCKSLGRFPNGKVKEP------PILR-----------VGVTANFFCDEGYRL------ 248
+A C NG + P PIL+ GV NF + +
Sbjct: 2144 DAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAV 2203
Query: 249 -QGPPSSR---CVIAGQGVAWTKMPVCEEIF------------------------CPSPP 280
GP + V +G T ++ C PP
Sbjct: 2204 WDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPPP 2263
Query: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
+ + + G V Y C P + L+G L C + SQ + G P
Sbjct: 2264 AVPQAEMLTED-DDFEIGDFVKYQCHP------GYTLVGTDILTCKLSSQL--QFEGSLP 2314
Query: 341 RCELSTSAVQCPHPQILRG 359
CE QCP ++ G
Sbjct: 2315 TCE-----AQCPANEVRTG 2328
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 7/65 (10%)
Query: 407 EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-GEESIQCTSEG---VWTPP 462
+ EC P +NG+ R RF G+S+ + C+ G+V G ESI C + VW+
Sbjct: 695 QNECHDPGIPINGR---RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSST 751
Query: 463 VPQCK 467
VP+C+
Sbjct: 752 VPRCE 756
Score = 38.1 bits (87), Expect = 0.046
Identities = 126/608 (20%), Positives = 218/608 (35%), Gaps = 131/608 (21%)
Query: 374 TVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGT 433
TV F+C G+TL + + C W + P C+ C +G F P +
Sbjct: 895 TVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNS 954
Query: 434 -----SIKYSCNPGYVLV--------GEESIQCTSEGVWTPPVPQCKVAACEATGRQLL- 479
+I+ S G ++ + + T +G ++ PV + + T + L
Sbjct: 955 LNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLF 1014
Query: 480 --TKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYN-- 535
Q +F+ D + S EG+ ++ S Y ++ C + P P
Sbjct: 1015 GNFTAQLRFI-SDFSISY-EGFNITFSEY-----------DLEPCDD---PGVPAFSRRI 1058
Query: 536 GAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLC-- 593
G H F G ++T++C G + L G + + C R WS P P C
Sbjct: 1059 GFH-------FGVGDSLTFSCFLG------YRLEGATKLTCLGGG--RRVWSAPLPRCVA 1103
Query: 594 ---------KLSLLAVQCSHVHIANG---YKISGKEAPYFYNDTVTFKCYSGFTLK---- 637
+ +LL+ + N YKI + + T +F+ + G TLK
Sbjct: 1104 ECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDG 1163
Query: 638 --GSSQ--------------IRCKADNTW---DPEIPVCEKG------------CQSPPG 666
SS+ + +++ W + ++G C+ P
Sbjct: 1164 KDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGI 1223
Query: 667 LHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WSPSAPRCEETCQH 723
++G F + V Y+C+PGY + G+ ++ C+ SG+ W P C C
Sbjct: 1224 PNYGYRIRDEGHF--TDTVVLYSCNPGYAMHGSNTLTCL-SGDRRVWDKPLPSCIAECG- 1279
Query: 724 VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH----CH 779
++ A + +++ Y H + +A+ G K I L ++ H
Sbjct: 1280 -----GQIHAATSGRILSPGYPAPYDNNLHCTWII-EADPG---KTISLHFIVFDTEMAH 1330
Query: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
+ +G + G+ + + F L + DS S SG S Q
Sbjct: 1331 DILKVWDGPVDSDILLKEWSGSALPEDIHSTF-----NSLTLQFDSDFFISKSGFSIQFS 1385
Query: 840 RSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT---W 895
S T C +P + ++G + + A D V C+PG+ + G I C N W
Sbjct: 1386 TSIAAT-CNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAKITCVQLNNRFFW 1441
Query: 896 VPGVPTCI 903
P PTCI
Sbjct: 1442 QPDPPTCI 1449
Score = 36.2 bits (82), Expect = 0.17
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)
Query: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEAR 214
P +P+ NGH + G + +VT+SC+ GY L ++ + C + +W+ P+C +A
Sbjct: 877 PGIPV--NGHRHGGDFGIRS---TVTFSCDPGYTLSDDEPLVCERNHQWNHALPSC-DAL 930
Query: 215 CKSLGRFPNGKVKEP 229
C + +G V P
Sbjct: 931 CGGYIQGKSGTVLSP 945
Score = 33.5 bits (75), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 2/40 (5%)
Query: 929 FSPGMSILYSCDQGYLLVGEALLLCTHEG--TWSQPAPHC 966
F G S+ +SC GY L G L C G WS P P C
Sbjct: 1062 FGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Score = 32.0 bits (71), Expect = 3.3
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 8/67 (11%)
Query: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE----GTWSQPAPH 965
C P+ G G + FS G + + C+ GYLL G L C W+ P
Sbjct: 1742 CSSVPEPRYGRRIG---SEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPS 1798
Query: 966 CKEVNCS 972
C V CS
Sbjct: 1799 C-VVPCS 1804
Score = 31.6 bits (70), Expect = 4.3
Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
F+ P C S P GR + + G+++R+ C+ + L G +L C +
Sbjct: 1729 FVYQAVPRTSDTQCSSVPEPRYGR--RIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVP 1786
Query: 70 KVDGTWDKPAPKC 82
W+ P C
Sbjct: 1787 NALAQWNDTIPSC 1799
Score = 31.6 bits (70), Expect = 4.3
Identities = 15/62 (24%), Positives = 29/62 (46%), Gaps = 5/62 (8%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P + N G + ++ + +S++C+ G+ L G + C + W+ PSP
Sbjct: 1916 CQEPALPSNSIKIG---DRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRR--WNYPSPL 1970
Query: 838 CL 839
C+
Sbjct: 1971 CI 1972
Score = 30.8 bits (68), Expect = 7.3
Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Query: 990 YQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWNPPLAVC 1027
Y V++ +CE GY L+G C + +WN P +C
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 278 bits (711), Expect = 2e-74
Identities = 267/1031 (25%), Positives = 416/1031 (40%), Gaps = 110/1031 (10%)
Query: 26 PPPIL-NGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEY 84
PP IL N + + +G ++RY C F L+G + L C + ++ P P CE
Sbjct: 2296 PPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQ--FEGPPPICEV 2353
Query: 85 FNKYSSCPEPIV---PGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ---ANNMW 138
CP + G + S P + T + + N S+ + + +
Sbjct: 2354 H-----CPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
Query: 139 GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL 198
+ S + P L + + V S + + + +S + Y G KI
Sbjct: 2409 DEFEIFDGPSG---QSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKI---- 2461
Query: 199 SSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
++SA P C R G F G+ P G + +F C+ GYRL G + C
Sbjct: 2462 ---RYSA--PYCSLPRAPLHG-FILGQTSTQP----GGSIHFGCNAGYRLVGHSMAICTR 2511
Query: 259 AGQGV-AWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFI 316
QG W++ +P+C+ + C P NG G + G+ Y+C EG +
Sbjct: 2512 HPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEY---TVGTKAMYSCS----EGYHLQ 2564
Query: 317 LIGESTLRCTVDSQKTGTWSGP--APRCELSTSAVQCPHPQIL---RGRMVSGQKDRYTY 371
E+T C TG WS P+C V CP + GR + +Y +
Sbjct: 2565 AGAEATAECL----DTGLWSNRNVPPQCV----PVTCPDVSSISVEHGRWRLIFETQYQF 2616
Query: 372 NDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEK-ECQAPPNILNGQKEDRHMVR 428
++ C G+ G + IRC A G W S P C C P NG + V
Sbjct: 2617 QAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY 2676
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLT---KPQHQ 485
G + +SCN GY LVG +C + G+W+ +C C T ++ ++
Sbjct: 2677 ---GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHC-GTPEPIVNGHINGENY 2732
Query: 486 FVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLED 545
R V C G++L G + CQ W + C ++C P + H+ S +
Sbjct: 2733 SYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG---SPPHSQMSGDS 2789
Query: 546 FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
+ G V Y+C + +L+G ST C + G W+G P C + + V C
Sbjct: 2790 YTVGAVVRYSCIG------KRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGV-CGDP 2838
Query: 606 HI-ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GCQS 663
I A+G ++ P + F C +G L+GSS+ C+A+ +W P C C +
Sbjct: 2839 GIPAHGIRLGDSFDP---GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN 2895
Query: 664 PPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-TCQ 722
P + R + + F S + Y C GY G S HC +G W+ S P C C
Sbjct: 2896 PGTPSNARVVFSDGLVFSSSIV--YECREGYYATGLLSRHCSVNGTWTGSDPECLVINCG 2953
Query: 723 HVRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
L G+ + V C GY + H + ++ W P+CK + C
Sbjct: 2954 DPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCK 3013
Query: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
PPP+I NGK G +F++G+ V+Y C +G+ L C +G+GSW+G PQC
Sbjct: 3014 PPPLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTC----EGNGSWTGELPQCF 3066
Query: 840 RSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGV 899
PV C +P V + + +S+ V C+P ++ GS C +D TW
Sbjct: 3067 ---PVF-CGDPGVPS--RGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQ 3120
Query: 900 PTCIKKAFIGCPPP--PKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 957
P+CI C P P+ N++ G + G ++L+ C +GYLL G C
Sbjct: 3121 PSCIDPTLTTCADPGVPQFGIQNNSQG----YQVGSTVLFRCQKGYLLQGSTTRTCLPNL 3176
Query: 958 TWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLE-GSPQSQCQS 1016
TWS P C +C P G + G + C++G+ L+ GS C++
Sbjct: 3177 TWSGTPPDCVPHHCRQPETPTHANVG--ALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKA 3234
Query: 1017 DHQWNPPLAVC 1027
D W +C
Sbjct: 3235 DGSWTGKPPIC 3245
Score = 272 bits (695), Expect = 1e-72
Identities = 239/856 (27%), Positives = 333/856 (38%), Gaps = 102/856 (11%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C P L+G I T G I + C+ +RL+G +C + W + P C
Sbjct: 2468 CSLPRAPLHGFI-LGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGP 140
+ SC P P + G Y G ++C + + C +W
Sbjct: 2527 QAL----SCGLPEAPKNGMVFGKE-YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSN 2581
Query: 141 TRLPT-CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYS--CESGYLLVGEKIINC 197
+P CV P+ CP + I H + C+ GY G+++I C
Sbjct: 2582 RNVPPQCV---PVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRC 2638
Query: 198 LSSGKWSA--VPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
++GKWS PTC C L PNG + + G TA F C+ GY L G
Sbjct: 2639 QANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAIFSCNSGYTLVGSRVRE 2697
Query: 256 CVIAGQGVAWTKMPV-CEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C+ G W+ V C C +P PI+NG HI N SY V Y C+
Sbjct: 2698 CMANG---LWSGSEVRCLAGHCGTPEPIVNG-HINGE--NYSYRGSVVYQCN------AG 2745
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
F LIG S C D WSG P C L V C HP +SG D YT
Sbjct: 2746 FRLIGMSVRICQQDHH----WSGKTPFCVL----VSCGHPGSPPHSQMSG--DSYTVGAV 2795
Query: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVR----FD 430
V ++C+ TL G+ C G W S P C + H +R FD
Sbjct: 2796 VRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSG---TSVGVCGDPGIPAHGIRLGDSFD 2852
Query: 431 PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPD 490
PGT +++SC G+VL G C + G W+ P+C V +C G T + V D
Sbjct: 2853 PGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPG----TPSNARVVFSD 2908
Query: 491 -------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSL 543
+ C EGY +G + + C W C I C P + NG G+
Sbjct: 2909 GLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGN-- 2966
Query: 544 EDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCS 603
DF Y TVTY C P G S + CT + TW+G P+CK A+ C
Sbjct: 2967 -DFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVCK----ALMCK 3013
Query: 604 HVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQS 663
+ K+ G + + + +VT+ C G+ L + C+ + +W E+P C
Sbjct: 3014 PPPLIPNGKVVGSD--FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
Query: 664 PPGL-HHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE--- 719
PG+ GR F +V ++C P +LVG+ C G WS + P C +
Sbjct: 3072 DPGVPSRGRREDRG---FSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 3128
Query: 720 -TCQH-------VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 771
TC ++ + Q GS V CQ GY L G + C N W P
Sbjct: 3129 TTCADPGVPQFGIQNNSQGYQVGSTVLF---RCQKGYLLQGSTTRTC--LPNLTWSGTPP 3183
Query: 772 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGS 830
C HC P + + + G + Y C +GF L G + C++D GS
Sbjct: 3184 DCVPHHCRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKAD----GS 3237
Query: 831 WSGPSPQCLRSPPVTR 846
W+G P CL P R
Sbjct: 3238 WTGKPPICLEVRPSGR 3253
Score = 222 bits (565), Expect = 2e-57
Identities = 224/879 (25%), Positives = 328/879 (37%), Gaps = 114/879 (12%)
Query: 72 DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVW 131
D +++ K Y Y S P + G I G T + G S+ F C + + G+
Sbjct: 2451 DHAYNRKGFKIRYSAPYCSLPRAPLHGF--ILGQTSTQPGGSIHFGCNAGYRLVGHSMAI 2508
Query: 132 C----QANNMWGPTRLPTC--VSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCES 185
C Q ++W +P C +S E P M+ +T G YSC
Sbjct: 2509 CTRHPQGYHLWSEA-IPLCQALSCGLPEAPKNGMVFGKEYTV--------GTKAMYSCSE 2559
Query: 186 GYLLVG--EKIINCLSSGKWSA--VPPTCEEARCKSLGRFPNGKVKEPPILRVGVTAN-- 239
GY L E CL +G WS VPP C C + + I
Sbjct: 2560 GYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQ 2619
Query: 240 --FFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSY 297
CD GY G RC G+ P C I C P NG IG Y
Sbjct: 2620 LMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSV---Y 2676
Query: 298 GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL 357
G+ ++C+ + L+G C + G WSG RC A C P+ +
Sbjct: 2677 GATAIFSCNS------GYTLVGSRVRECMAN----GLWSGSEVRC----LAGHCGTPEPI 2722
Query: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAPPNI 416
++G+ Y+Y +V++ C GF L G C W P C C P +
Sbjct: 2723 VNGHINGEN--YSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSP 2780
Query: 417 LNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATG 475
+ Q D + V G ++YSC LVG + C +G WT +P C + G
Sbjct: 2781 PHSQMSGDSYTV----GAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCG 2836
Query: 476 RQLLTKPQHQFVRPD-------VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCP 528
+ P H D + SC G+ L GS + CQ W C I+C
Sbjct: 2837 DPGI--PAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCG 2894
Query: 529 PPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG 588
P N S + + +++ Y C G + G + C+ N GTW+G
Sbjct: 2895 NPGTPSNARVVFS--DGLVFSSSIVYECREG------YYATGLLSRHCSVN----GTWTG 2942
Query: 589 PAPLCKLSLLAVQCSHVHI-ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGS--SQIRCK 645
P C L + C I ANG ++ + YN TVT++C G+ ++ S + C
Sbjct: 2943 SDPEC----LVINCGDPGIPANGLRLGND---FRYNKTVTYQCVPGYMMESHRVSVLSCT 2995
Query: 646 ADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
D TW+ PVC+ C+ PP + +G+ G + F+ G +V Y C GY L C
Sbjct: 2996 KDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTC 3052
Query: 705 MPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVE--------LVNTSCQDGYQLTGHAYQ 756
+G+W+ P+ C V +P+ R E V+ SC L G +
Sbjct: 3053 EGNGSWTGELPQ----CFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRR 3108
Query: 757 MCQDAENGIWFKKIPLC---KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYL 813
CQ +G W P C + C P V G ++ + G+ V + C +G+ L
Sbjct: 3109 FCQS--DGTWSGTQPSCIDPTLTTCADPGVPQFGIQNN--SQGYQVGSTVLFRCQKGYLL 3164
Query: 814 LGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYV 873
G C + +WSG P C+ C PE + ++Y
Sbjct: 3165 QGSTTRTCLPNL----TWSGTPPDCVPH----HCRQPETPTHANVGALDLPSMGYTLIY- 3215
Query: 874 DCNPGFIMNGSRVIR-CHTDNTWVPGVPTCIKKAFIGCP 911
C GF + G R C D +W P C++ G P
Sbjct: 3216 SCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRP 3254
Score = 182 bits (463), Expect = 1e-45
Identities = 154/564 (27%), Positives = 224/564 (39%), Gaps = 60/564 (10%)
Query: 491 VNSSCGEGYKLSGSVYQEC----QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDF 546
++ C GY+L G C QG W I LC+ ++C P NG G +++
Sbjct: 2491 IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFG---KEY 2547
Query: 547 PYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGP--APLCKLSLLAVQCSH 604
GT Y+C+ G E+T C + G WS P C + + S
Sbjct: 2548 TVGTKAMYSCS----EGYHLQAGAEATAECL----DTGLWSNRNVPPQC-VPVTCPDVSS 2598
Query: 605 VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWD--PEIPVCEK-GC 661
+ + +G E Y + + C G+ G IRC+A+ W P C C
Sbjct: 2599 ISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISC 2658
Query: 662 QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EET 720
P +G G +V+ G T ++C+ GY LVG++ CM +G WS S RC
Sbjct: 2659 GELPIPPNGHRIGTLSVY---GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGH 2715
Query: 721 CQHVRQSLQELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 777
C + G V C G++L G + ++CQ + W K P C ++
Sbjct: 2716 CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHH--WSGKTPFCVLVS 2773
Query: 778 C-HP--PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 834
C HP PP H+ M +++ G V Y C L+G C D G W+G
Sbjct: 2774 CGHPGSPP------HSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLD----GHWTGS 2823
Query: 835 SPQCLRSPPVTRCPNPEVK-HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN 893
P C V C +P + HG +L ++ ++ C G ++ GS C +
Sbjct: 2824 LPHC-SGTSVGVCGDPGIPAHGIRLG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANG 2879
Query: 894 TWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLC 953
+W P C I C P N + FS SI+Y C +GY G C
Sbjct: 2880 SWSGSQPEC---GVISCGNPGTPSNARVVFSDGLVFSS--SIVYECREGYYATGLLSRHC 2934
Query: 954 THEGTWSQPAPHCKEVNCSSPADMDGI-QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS 1012
+ GTW+ P C +NC P GI GL ++Y VT +C GYM+E S
Sbjct: 2935 SVNGTWTGSDPECLVINCGDP----GIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVS 2990
Query: 1013 --QCQSDHQWNPPLAVCRSRSLAP 1034
C D WN VC++ P
Sbjct: 2991 VLSCTKDRTWNGTKPVCKALMCKP 3014
Score = 100 bits (250), Expect = 6e-21
Identities = 241/1130 (21%), Positives = 381/1130 (33%), Gaps = 264/1130 (23%)
Query: 10 FLALVAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKD 69
F+ P C S P G+ + +VG ++R+ C+ + L G + C+
Sbjct: 1722 FVYQAVPRTSATQCSSVPEPRYGK--RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVP 1779
Query: 70 KVDGTWDKPAPKC----------------------EYFNKYSSCPEPIVPGGYKIR---- 103
W+ AP C Y N + + +VP G I+
Sbjct: 1780 GALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVV 1839
Query: 104 --------GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN---MWGPTRLPTCVSVFPL 152
S G T +FS ++ +N + + + + F L
Sbjct: 1840 SFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHL 1899
Query: 153 E--------CPALPMIHNGHHTSEN--VGSIAPGLSVTYSCESGYLLVGEKIINCLSSG- 201
E CP + NG T E V + V++ CE GY L G I+C+
Sbjct: 1900 EYKTVGLSSCPEPAVPSNGVKTGERYLVNDV-----VSFQCEPGYALQGHAHISCMPGTV 1954
Query: 202 -KWSAVPPTCEEARCKSLGRFPNGKVKEPP--ILRVGVTANFFCDEGYRLQGPPSSRCVI 258
+W+ PP C A+C G V+E IL G N+ P + C
Sbjct: 1955 RRWNYPPPLCI-AQC-------GGTVEEMEGVILSPGFPGNY----------PSNMDC-- 1994
Query: 259 AGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILI 318
+W K+ + P+ G HI + ++ +P+ + +I I
Sbjct: 1995 -----SW-KIAL----------PVGFGAHI----------QFLNFSTEPNHD----YIEI 2024
Query: 319 GESTLRCTVDSQKTGTWSGPA-PRCELSTSA-----VQCPHPQILRGRMVSGQKDRYTYN 372
S+ G +SG P LSTS H Q G + Q Y++
Sbjct: 2025 RNGPYET---SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQ 2081
Query: 373 DTVIFACMFGFTLKGSKQIRCN----AQGTWEPSAPVCE----KECQAPPNILNGQKEDR 424
I + + GF L ++ A W+ P CE +EC P NG
Sbjct: 2082 ---ISSFLRGFDLSELERTNSTPPVAASYVWDLD-PGCEAYELQECPDPEPFANG----- 2132
Query: 425 HMVR---FDPGTSIKYSCNPGYVLVGEESIQCT--SEGVWTPPVPQCKVAACEATGRQLL 479
+VR ++ G S+ + C PGY L G + C + W P+P+C+V
Sbjct: 2133 -IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC--------- 2182
Query: 480 TKPQHQFVRPDVNSSCGEGYKLS-GSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAH 538
++ SS G Y S Y Q + W + + P+ +
Sbjct: 2183 --------GGNITSSNGTVYSPGFPSPYSSSQDCV-WLITV-----------PIGHGVRL 2222
Query: 539 TGSSLEDFPYGTTVTYTCNP---GPERGVEFSLIGESTIRCTSND-----QERGTWSGPA 590
S L+ P G +T P P GV + + T++ +SN G
Sbjct: 2223 NLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIF 2282
Query: 591 PLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN-- 648
+ + +C I ++ + + D V ++C GFTL G+ + CK
Sbjct: 2283 AIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYL 2342
Query: 649 TWDPEIPVCEKGC---------------QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG 693
++ P+CE C QS PG + T V + T +
Sbjct: 2343 QFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVE-- 2400
Query: 694 YLLVGNK----SIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQ 749
Y L + I PSG SP L+ L L+ TS +
Sbjct: 2401 YFLSEKQYDEFEIFDGPSGQ-SP--------------LLKALSGNYSAPLIVTSSSNSVY 2445
Query: 750 L---TGHAYQMCQDAENGIWFK---KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 803
L + HAY N FK P C + P ++G G + G +
Sbjct: 2446 LRWSSDHAY-------NRKGFKIRYSAPYCSL-----PRAPLHGFILGQTSTQ--PGGSI 2491
Query: 804 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTH 862
+ C+ G+ L+G C +G+ WS P C C PE K+G K
Sbjct: 2492 HFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC----QALSCGLPEAPKNGMVFGK-- 2545
Query: 863 SAYSHNDIVYVDCNPGFIM--NGSRVIRCHTDNTW----VPGVPTCIKKAFIGCPPPP-- 914
Y+ C+ G+ + C W VP P C+ + CP
Sbjct: 2546 -EYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVP--PQCVP---VTCPDVSSI 2599
Query: 915 KTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWS--QPAPHCKEVNCS 972
+G ++ ++ CD GY G+ ++ C G WS P C+ ++C
Sbjct: 2600 SVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCG 2659
Query: 973 S-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
P +G + G + YGA C GY L GS +C ++ W+
Sbjct: 2660 ELPIPPNGHRIG----TLSVYGATAIFSCNSGYTLVGSRVRECMANGLWS 2705
Score = 93.6 bits (231), Expect = 9e-19
Identities = 76/275 (27%), Positives = 120/275 (43%), Gaps = 24/275 (8%)
Query: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
P + C PP I NG++ + G+ + Y+C ++L SL + + +G+W
Sbjct: 3005 PVCKALMCKPPPLIPNGKV--VGSDFMWGSSVTYACLEGYQL----SLPAVFTCEGNGSW 3058
Query: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
P+C F + C +P VP + R + + SV+F+C + G+ +CQ++
Sbjct: 3059 TGELPQC--FPVF--CGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSD 3113
Query: 136 NMWGPTRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
W T+ P+C+ C P +P N G +V + C+ GYLL G
Sbjct: 3114 GTWSGTQ-PSCIDPTLTTCADPGVPQFG----IQNNSQGYQVGSTVLFRCQKGYLLQGST 3168
Query: 194 IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPS 253
CL + WS PP C C+ + V + +G T + C EG+ L+G
Sbjct: 3169 TRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSE 3228
Query: 254 SR-CVIAGQGVAWT-KMPVCEEIFCPSPPPILNGR 286
R C G +WT K P+C E+ PS PI R
Sbjct: 3229 HRTCKADG---SWTGKPPICLEV-RPSGRPINTAR 3259
Score = 71.6 bits (174), Expect = 4e-12
Identities = 215/1037 (20%), Positives = 355/1037 (34%), Gaps = 211/1037 (20%)
Query: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF 150
C +P +P + G+ Y G VTF+C + ++++ + + C+ N W LP+C ++
Sbjct: 867 CLDPGIPVNGQRHGNDFYV-GALVTFSCDSGYTLSDGEPLECEPNFQWSRA-LPSCEALC 924
Query: 151 ---------PLECPALPMIHNGHHTSENVGSIAPGLSV-----TYSCESG--YLLV---- 190
+ P P + + + + G V T+ ESG YLL+
Sbjct: 925 GGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENG 984
Query: 191 ----------GEKIINCLSSGKWSAVPPTCE---------EARCKSLGRFPNGKVKEPPI 231
G ++ +S+G + E + + +EP +
Sbjct: 985 SFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEV 1044
Query: 232 ----------LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPSPP 280
VG T F C GYRL+G C + G+ W+ +P C
Sbjct: 1045 PAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPLPRCVA------- 1096
Query: 281 PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAP 340
GNS+ G++++ P VN+ + C Q + P
Sbjct: 1097 ------ECGNSVTGTQ-GTLLS------PNFPVNY----NNNHECIYSIQ-----TQPGK 1134
Query: 341 RCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQ-----IRCNA 395
+L A + +L+ + G + + M G TL + +A
Sbjct: 1135 GIQLKARAFELSEGDVLK--VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDA 1192
Query: 396 QGT---WEPSAPVCEK-ECQAPPNILNGQK--EDRHMVRFDPGTSIKYSCNPGYVLVGEE 449
+ T +E E +C+ P G K ++ H G+S+ +SC+PGY L G E
Sbjct: 1193 ENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFA----GSSVSFSCDPGYSLRGSE 1248
Query: 450 SIQCTS--EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQ 507
+ C S W P+P C VA C T R ++ Q + P + ++
Sbjct: 1249 ELLCLSGERRTWDRPLPTC-VAECGGTVRGEVSG---QVLSPGYPAPYEHNLNCIWTIEA 1304
Query: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFS 567
E TI + +E+ H + D P + V GP +
Sbjct: 1305 EAGCTIGLHFLVFDTEEV------------HDVLRIWDGPVESGVLLKELSGPALPKDLH 1352
Query: 568 LIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVT 627
S + S D G A +S A C+ I SG + D+
Sbjct: 1353 STFNSVVLQFSTDFFTSK-QGFAIQFSVST-ATSCNDPGIPQNGSRSGDS--WEAGDSTV 1408
Query: 628 FKCYSGFTLKGSSQIRC-KADNT--WDPEIPVCEKGCQSPPGLHHGRHTGGNTVF----- 679
F+C G+ L+GS++I C K +N W P P C C G TG + V
Sbjct: 1409 FQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCG-------GDLTGPSGVILSPNY 1461
Query: 680 ---FVSGMTVDY--TCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAG 734
+ G D+ T P Y++ +I + G ++ + S
Sbjct: 1462 PEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP 1521
Query: 735 SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMA 794
R+E S + L + +A I + + P C P I NG G
Sbjct: 1522 GRIE----SSSNSLFLAFRSDASVSNAGFVIDYTENPRES---CFDPGSIKNGTRVG--- 1571
Query: 795 ENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC--------LRSPPVTR 846
+ G+ V+Y C G+ + G L C G W+ P P C + S V
Sbjct: 1572 SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVL 1631
Query: 847 CPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG---------SRVIRCHTDNTWVP 897
PN Y N T + +V +++ G + V+ H ++
Sbjct: 1632 SPN------YPQNYTSGQIC---LYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHS 1682
Query: 898 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 957
+ + + +G+HTG ++ + ++ +G L G
Sbjct: 1683 RLLSSL--------------SGSHTGESLPLATSNQVLIKFSAKG---------LAPARG 1719
Query: 958 TWS--QPAPHCKEVNCSS-PADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 1014
Q P CSS P G + G + + GA+V EC GY L+GSP+ +C
Sbjct: 1720 FHFVYQAVPRTSATQCSSVPEPRYGKRLGSD----FSVGAIVRFECNSGYALQGSPEIEC 1775
Query: 1015 ----QSDHQWNPPLAVC 1027
+ QWN C
Sbjct: 1776 LPVPGALAQWNVSAPTC 1792
Score = 70.1 bits (170), Expect = 1e-11
Identities = 166/840 (19%), Positives = 269/840 (32%), Gaps = 162/840 (19%)
Query: 85 FNKYS--SCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN--MWGP 140
F++Y C EP VP Y IR + GD++TF+C + + G + C +W
Sbjct: 1031 FSEYDLEPCEEPEVPA-YSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS- 1088
Query: 141 TRLPTCVSVF---------PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVG 191
+ LP CV+ L P P+ +N +H PG + + L G
Sbjct: 1089 SPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG 1148
Query: 192 EKI-------------------------INCLSSGKWSAVPPTCEEA------------- 213
+ + +N SS W E
Sbjct: 1149 DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFEL 1208
Query: 214 -RCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVC 271
+C+ G G G + +F CD GY L+G C ++G+ W + +P C
Sbjct: 1209 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC-LSGERRTWDRPLPTC 1267
Query: 272 EEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTV---- 327
G ++ G +++ E +N I E+ CT+
Sbjct: 1268 VA-------------ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF 1314
Query: 328 ---DSQKTGT----WSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACM 380
D+++ W GP L P+ L T+N V+
Sbjct: 1315 LVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHS----------TFNSVVLQFST 1364
Query: 381 FGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
FT K I+ + C P NG + ++ G S + C+
Sbjct: 1365 DFFTSKQGFAIQFSVSTA---------TSCNDPGIPQNGSRSGDS---WEAGDSTVFQCD 1412
Query: 441 PGYVLVGEESIQCT---SEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGE 497
PGY L G I C + W P P C +A C LT P + P+
Sbjct: 1413 PGYALQGSAEISCVKIENRFFWQPSPPTC-IAPCGGD----LTGPSGVILSPNYPEPYPP 1467
Query: 498 GYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV----IYNGAHTGSSLEDFPYGTTVT 553
G + V T+ I L I P IY+G + S L YG+ +
Sbjct: 1468 GKECDWKV------TVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQL- 1520
Query: 554 YTCNPGPERGVEFSLIGESTIRCTSNDQERG----TWSGPAPLCKLSLLAVQCSHVHIAN 609
PG SL R ++ G P C I N
Sbjct: 1521 ----PGRIESSSNSLF--LAFRSDASVSNAGFVIDYTENPRESC--------FDPGSIKN 1566
Query: 610 GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC----KADNTWDPEIPVCEKGCQSPP 665
G ++ + +VT+ C+ G+ ++G+S + C W+ PVC C
Sbjct: 1567 GTRVG---SDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPC---- 1619
Query: 666 GLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ--- 722
G++ G + V +YT L + G ++ + +
Sbjct: 1620 ---GGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHD 1676
Query: 723 -HVRQS--LQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
H + S L L E + + + + A + ++ +P C
Sbjct: 1677 GHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCS 1736
Query: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCL 839
P GK G +F G V +EC+ G+ L G +++C W+ +P C+
Sbjct: 1737 SVPEPRYGKRLG---SDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV 1793
Score = 60.1 bits (144), Expect = 1e-08
Identities = 106/461 (22%), Positives = 160/461 (34%), Gaps = 83/461 (18%)
Query: 620 YFYNDTVTFKCYS--GFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNT 677
Y Y T K +S GF L+ + I ++D+ DP IPV G HG
Sbjct: 837 YLYLLFSTDKSHSDIGFQLRYET-ITLQSDHCLDPGIPV--------NGQRHGND----- 882
Query: 678 VFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV 737
F G V ++CD GY L + + C P+ WS + P CE C Q GS
Sbjct: 883 --FYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQ-------GSSG 933
Query: 738 ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV-NGKHTGMMAEN 796
+++ D Y + + + + F + H +I NG T + +
Sbjct: 934 TILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQ- 992
Query: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
L G+ + G Y G Q R S S+ G + + C PEV Y
Sbjct: 993 -LTGSRLPAPISAGLY--GNFTAQVRFISDFSMSYEGFN-ITFSEYDLEPCEEPEVP-AY 1047
Query: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC--HTDNTWVPGVPTCI---------KK 905
+ K + D + C PG+ + G+ I C W +P C+ +
Sbjct: 1048 SIRK-GLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQ 1106
Query: 906 AFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE-------GT 958
+ P P N NH + PG I L G+ L + G
Sbjct: 1107 GTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGV 1166
Query: 959 WSQPAPHCKEVNCSSPA-------DMDGIQKGLE----------------PRKMYQY--- 992
+S +N +S + D + KG E P+ Y+
Sbjct: 1167 FSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDE 1226
Query: 993 ----GAVVTLECEDGYMLEGSPQSQCQSDHQ--WNPPLAVC 1027
G+ V+ C+ GY L GS + C S + W+ PL C
Sbjct: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 1267
Score = 59.7 bits (143), Expect = 1e-08
Identities = 206/1028 (20%), Positives = 342/1028 (33%), Gaps = 189/1028 (18%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SCG P GR + G +++ C F L+G+K++ C + + W P
Sbjct: 520 SCGDPGIPAYGRRE--GSRFHHGDTLKFECQPAFELVGQKAITC----QKNNQWSAKKPG 573
Query: 82 CEY--FNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
C + F ++S P G + + P +G+ + C + N++
Sbjct: 574 CVFSCFFNFTS------PSGVVLSPNYPEDYGNHLH--CVWLILARPESRIHLAFNDIDV 625
Query: 140 PTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLS 199
+ V I +G V G + S S + + S
Sbjct: 626 EPQFDFLV------------IKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHS 673
Query: 200 SGK--WSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYR-LQGPPSSRC 256
+GK ++ T C G NGK + L++G + +F CDEG+ QG + C
Sbjct: 674 TGKRGFNITFTTFRHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITC 732
Query: 257 VIAGQGVAWTKMPV-CEE------------IFCPSPPPILNGRHIGNSLANVSYGSIVTY 303
V+ V W + CE I P P + G +
Sbjct: 733 VLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKI 792
Query: 304 TCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGP-APRCELSTS-------AVQCPHPQ 355
T D E VN+ + R T + G + G P+ +STS + H
Sbjct: 793 TFDRFKTE-VNYDTLEVRDGR-TYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
Query: 356 I---LRGRMVSGQKDR----------------YTYNDTVIFACMFGFTLKGSKQIRCNAQ 396
I LR ++ Q D + V F+C G+TL + + C
Sbjct: 851 IGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPN 910
Query: 397 GTWEPSAPVCEKEC-------------QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
W + P CE C P+ ++ G + ++ + +
Sbjct: 911 FQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFH 970
Query: 444 VLVGEESIQCTSEGVWTPPVPQ---CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500
+ G + + T G +T P+ Q ++ A + G Q +F+ D + S EG+
Sbjct: 971 LESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFI-SDFSMSY-EGFN 1028
Query: 501 LSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGP 560
++ S Y ++ C+E P A++ F G T+T++C PG
Sbjct: 1029 ITFSEY-----------DLEPCEEPEVP--------AYSIRKGLQFGVGDTLTFSCFPG- 1068
Query: 561 ERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPY 620
+ L G + I C R WS P P C +C + + P
Sbjct: 1069 -----YRLEGTARITCLGG--RRRLWSSPLPRC-----VAECGNSVTGTQGTLLSPNFPV 1116
Query: 621 FYNDTVTFKC-YSGFTLKGSS-QIRCKADNTWDPEIPVCEKGCQSPPGL----HHGRHTG 674
YN+ +C YS T G Q++ +A + ++ G + L H G
Sbjct: 1117 NYNN--NHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMG 1174
Query: 675 GNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAG 734
S + +D+ D G + +H P + V + AG
Sbjct: 1175 VTLNSTSSSLWLDFITDAENTSKGFE-LHFSSFELIKCEDPGTPKFGYKVHD--EGHFAG 1231
Query: 735 SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMA 794
S V SC GY L G +C E W + +P C V C V G+ +G +
Sbjct: 1232 SSVSF---SCDPGYSLRGSEELLCLSGERRTWDRPLPTC-VAECGG---TVRGEVSGQVL 1284
Query: 795 E-----------NFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPP 843
N ++ E C G + L + + W GP +
Sbjct: 1285 SPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLR---IWDGPVESGVLLKE 1341
Query: 844 VTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM--NGSRVIRCHTDNTWVPGVPT 901
++ P+ H N +S + + GF + + S C+ PG+P
Sbjct: 1342 LSGPALPKDLHS-TFNSVVLQFSTD---FFTSKQGFAIQFSVSTATSCND-----PGIP- 1391
Query: 902 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT---HEGT 958
NG+ +G + + G S ++ CD GY L G A + C +
Sbjct: 1392 ---------------QNGSRSGDS---WEAGDSTVFQCDPGYALQGSAEISCVKIENRFF 1433
Query: 959 WSQPAPHC 966
W P C
Sbjct: 1434 WQPSPPTC 1441
Score = 58.5 bits (140), Expect = 3e-08
Identities = 138/648 (21%), Positives = 224/648 (34%), Gaps = 119/648 (18%)
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEG----VWTPPVPQCKVAACEATGRQ---LLTK 481
F G+S++++CN GY L G + I C W+ P C+ C+A R ++T
Sbjct: 359 FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITS 418
Query: 482 PQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGS 541
P ++ D N+ C W IT P + A
Sbjct: 419 PNFP-IQYDNNAHC------------------VWI--------ITALNPSKVIKLAFEEF 451
Query: 542 SLEDFPYGTTVTYTCNPGPERGVEFSLIGEST--IRCTSNDQE----RGTWSGPAPLCKL 595
LE TV G ++ V + L G S + ++N Q + SG + K
Sbjct: 452 DLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKA 511
Query: 596 SLLAVQ---CSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDP 652
S ++ C I + G + + DT+ F+C F L G I C+ +N W
Sbjct: 512 SYEEIEQGSCGDPGIPAYGRREGSR--FHHGDTLKFECQPAFELVGQKAITCQKNNQWSA 569
Query: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSP 712
+ P C C FF P Y +HC+ W
Sbjct: 570 KKPGCVFSC-----------------FFNFTSPSGVVLSPNYPEDYGNHLHCV----WLI 608
Query: 713 SAPRCEETCQHVRQSLQELPA--------GSRVELVNTSCQDGYQL------TGHAYQM- 757
A R E + P G+ E G QL +GH ++
Sbjct: 609 LA-RPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLE 667
Query: 758 -CQDAENGIWFKKIPLCKVIH--CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFY-L 813
D G I H C P V VNGK G ++ G+ +S+ CD+GF
Sbjct: 668 FQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGT 724
Query: 814 LGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIV-- 871
G + + C +G W+ +C +P +P G L+ + + +
Sbjct: 725 QGSETITCVL-KEGSVVWNSAVLRC-EAPCGGHLTSPS---GTILSPGWPGFYKDALSCA 779
Query: 872 -YVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS 930
++ PG+ + I T V ++ P +G + S
Sbjct: 780 WVIEAQPGYPIK----ITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTS 835
Query: 931 PGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMY 990
+ +L+S D+ + +G L T + + HC + ++G + G + +
Sbjct: 836 NYLYLLFSTDKSHSDIGFQL----RYETITLQSDHCLDPGIP----VNGQRHGND----F 883
Query: 991 QYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCG 1038
GA+VT C+ GY L +C+ + QW+ L C + LCG
Sbjct: 884 YVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA------LCG 925
Score = 55.5 bits (132), Expect = 3e-07
Identities = 185/897 (20%), Positives = 292/897 (32%), Gaps = 198/897 (22%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G ++ + C+ + LVG+K I C + +WSA P C + C P+G V P
Sbjct: 540 GDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFS-CFFNFTSPSGVVLSP------ 592
Query: 236 VTANFFCDEGYRLQ------GPPSSRCVIAGQGVAWTKMPVCEEIF----CPSPPPILNG 285
N+ D G L P SR +A + P + + + P+L G
Sbjct: 593 ---NYPEDYGNHLHCVWLILARPESRIHLAFNDI--DVEPQFDFLVIKDGATAEAPVL-G 646
Query: 286 RHIGNSLAN--VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCE 343
GN L + S G + D G I +T R
Sbjct: 647 TFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHN----------------- 689
Query: 344 LSTSAVQCPHPQILRGRMVSGQK--DRYTYNDTVIFACMFGFT-LKGSKQIRC---NAQG 397
+CP P G V+G++ D ++ F C GF +GS+ I C
Sbjct: 690 ------ECPDP----GVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSV 739
Query: 398 TWEPSAPVCEKECQAP-------------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYV 444
W + CE C P ++ PG IK + +
Sbjct: 740 VWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKT 799
Query: 445 LVGEESIQCTSEGVWTPP---------VPQCKVAACEATGRQLLTKPQHQFVRPDVNSSC 495
V ++++ ++ P VPQ ++ T H +
Sbjct: 800 EVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDI-------- 851
Query: 496 GEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYT 555
G++L E + C P + NG G+ DF G VT++
Sbjct: 852 --GFQLR--------------YETITLQSDHCLDPGIPVNGQRHGN---DFYVGALVTFS 892
Query: 556 CNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISG 615
C+ G ++L + C N Q WS P C+ C + I
Sbjct: 893 CDSG------YTLSDGEPLECEPNFQ----WSRALPSCE-----ALCGGFIQGSSGTILS 937
Query: 616 KEAPYFYNDTVT-------------FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
P FY + + F + F L+ +N + G +
Sbjct: 938 PGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSR 997
Query: 663 SPPGLHHGRHTGGN---TVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + G + GN V F+S ++ Y G+ + ++ CEE
Sbjct: 998 LPAPISAGLY--GNFTAQVRFISDFSMSYE---GFNITFSEY-----------DLEPCEE 1041
Query: 720 T---CQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVI 776
+R+ LQ G + + SC GY+L G A C +W +P C V
Sbjct: 1042 PEVPAYSIRKGLQ-FGVG---DTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC-VA 1096
Query: 777 HCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEK--KLQCRSDSKGHGSWSGP 834
C V G +++ NF ++EC K +L+ R+ G
Sbjct: 1097 ECGNS---VTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV 1153
Query: 835 SPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVD-CNPGFIMNGS--RVIRCHT 891
S + + G LN T S+ + I + + GF ++ S +I+C
Sbjct: 1154 YDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCED 1213
Query: 892 DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALL 951
T PK H G+ A G S+ +SCD GY L G L
Sbjct: 1214 PGT-------------------PKFGYKVHDEGHFA----GSSVSFSCDPGYSLRGSEEL 1250
Query: 952 LCT--HEGTWSQPAPHC-KEVNCSSPADMDG--IQKGLEPRKMYQYGAVVTLECEDG 1003
LC TW +P P C E + ++ G + G + + T+E E G
Sbjct: 1251 LCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1307
Score = 54.7 bits (130), Expect = 5e-07
Identities = 109/476 (22%), Positives = 164/476 (34%), Gaps = 98/476 (20%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
SC P I NG + + + +G+ + Y C G + + G +L CI W+ P P
Sbjct: 1557 SCFDPGSIKNG--TRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
Query: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
C P G + GS D V + N+ N C ++ T
Sbjct: 1615 C------------TAPCGGQYVGS------DGVVLS--PNYPQNYTSGQIC----LYFVT 1650
Query: 142 RLPTCV-----SVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIIN 196
V + F + +H+GH + S LS +++ ES L +++
Sbjct: 1651 VPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLS---SLSGSHTGESLPLATSNQVLI 1707
Query: 197 CLSSG----------KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGY 246
S+ + AVP T +C S+ GK + VG F C+ GY
Sbjct: 1708 KFSAKGLAPARGFHFVYQAVPRT-SATQCSSVPEPRYGK-RLGSDFSVGAIVRFECNSGY 1765
Query: 247 RLQGPPSSRCV-IAGQGVAW-TKMPVC------------EEIFCPS-PPPILNGRH---- 287
LQG P C+ + G W P C I P P P LN +
Sbjct: 1766 ALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWK 1825
Query: 288 ------IGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
G + VS+ + + + N + + S TV + T +
Sbjct: 1826 IVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLH 1885
Query: 342 --CELSTSAV------------QCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKG 387
++S SA CP P + + +G +RY ND V F C G+ L+G
Sbjct: 1886 FYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTG--ERYLVNDVVSFQCEPGYALQG 1943
Query: 388 SKQIRCNAQGT---WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCN 440
I C GT W P+C +C G E+ V PG Y N
Sbjct: 1944 HAHISC-MPGTVRRWNYPPPLCIAQC-------GGTVEEMEGVILSPGFPGNYPSN 1991
Score = 53.1 bits (126), Expect = 1e-06
Identities = 117/549 (21%), Positives = 190/549 (34%), Gaps = 117/549 (21%)
Query: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
P P+ LR R+ Q I + +L+ +AQG + C
Sbjct: 87 PQPENLRTRLTGFQLP------ATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCG 140
Query: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQC----TSEGVWTPPVPQCK 467
P + NG ++ F+ G ++YSCN G+ L G + C + W P+P C+
Sbjct: 141 NPGRLPNGIQQGS---TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCR 197
Query: 468 V-AACEAT--GRQLLTKPQHQFVRPDVNSSC--------GEGYKL--------SGSVYQE 508
AC T G+ + H N+ C G+ L G + E
Sbjct: 198 ADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLE 257
Query: 509 CQGT---IPWFMEIRLCKEITCPPPPVI----YNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
GT WF L P PVI + H S G + Y +
Sbjct: 258 VTGTEGSSLWFTGASL-------PAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV----K 306
Query: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIAN-GYKISGKE--A 618
+ +E G + N Q+ L+ + V H + G GK +
Sbjct: 307 KQIELKSRGVKLMPSKDNSQKTSV---------LTQVGVSQGHNMCPDPGIPERGKRLGS 357
Query: 619 PYFYNDTVTFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCE-KGCQSPPGLHHGRHT 673
+ +V F C G+ L+GS +I C + W PVC + C + H
Sbjct: 358 DFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDA--------HL 409
Query: 674 GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPA 733
G + S P + + + + HC+ W +A + + + +L
Sbjct: 410 RGPSGIITS---------PNFPIQYDNNAHCV----WIITALNPSKVIKLAFEEF-DLER 455
Query: 734 GSRVELVNTSCQDG------YQLTGHA---------YQM-----CQDAENGIWFK-KIPL 772
G V QDG Y LTG + +QM + + + FK
Sbjct: 456 GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEE 515
Query: 773 CKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWS 832
+ C P + G+ G F +G+ + +EC F L+G+K + C+ +++ WS
Sbjct: 516 IEQGSCGDPGIPAYGRREG---SRFHHGDTLKFECQPAFELVGQKAITCQKNNQ----WS 568
Query: 833 GPSPQCLRS 841
P C+ S
Sbjct: 569 AKKPGCVFS 577
Score = 49.3 bits (116), Expect = 2e-05
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 70 KVDGTWDKPAPKCEYFN-KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNK 128
+ DG+ K Y + SC +P +P Y R + + HGD++ F C+ F + G K
Sbjct: 499 QTDGSGSSLGFKASYEEIEQGSCGDPGIPA-YGRREGSRFHHGDTLKFECQPAFELVGQK 557
Query: 129 SVWCQANNMWGPTRLPTCV 147
++ CQ NN W + P CV
Sbjct: 558 AITCQKNNQWS-AKKPGCV 575
Score = 45.8 bits (107), Expect = 2e-04
Identities = 108/506 (21%), Positives = 169/506 (33%), Gaps = 139/506 (27%)
Query: 165 HTSENVGSIAPGLS----------VTYSCESGYLLVGEKIINCLS----SGKWSAVPPTC 210
HT N G + G+ V YSC G+ L G ++ C + S W P+C
Sbjct: 137 HTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Query: 211 E-EARCKSLGRFPNGKVKEPP---------------ILRVGVTA-----NFFCDEGY--- 246
+ C R +G + P + +G T +F ++GY
Sbjct: 197 RADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFL 256
Query: 247 RLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGR-----HIGNSLANVSYGSIV 301
+ G S G + P P+++ + H + + G
Sbjct: 257 EVTGTEGSSLWFTGASL---------------PAPVISSKNWLRLHFTSDGNHRQRGFSA 301
Query: 302 TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL-RGR 360
Y ++ + G + +SQKT + + +S CP P I RG+
Sbjct: 302 QYQV----KKQIELKSRGVKLMPSKDNSQKTSVLT----QVGVSQGHNMCPDPGIPERGK 353
Query: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRC----NAQGTWEPSAPVCE-KECQA--- 412
+ + +V F C G+ L+GSK+I C + W PVC + C A
Sbjct: 354 RLGSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLR 410
Query: 413 -------PPNILNGQKEDRHMV----RFDPGTSIK-----YSCNPGYVLV-----GEESI 451
PN + H V +P IK + GY + G++
Sbjct: 411 GPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGD 470
Query: 452 QCTSEGVWT-PPVPQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510
Q T + T VP V+ T Q + S G+K S Y+E +
Sbjct: 471 QKTVLYILTGTSVPDLIVS----------TNHQMWLLFQTDGSGSSLGFKAS---YEEIE 517
Query: 511 GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570
+ +C P + G GS F +G T+ + C P F L+G
Sbjct: 518 -------------QGSCGDPGIPAYGRREGSR---FHHGDTLKFECQPA------FELVG 555
Query: 571 ESTIRCTSNDQERGTWSGPAPLCKLS 596
+ I C N+Q WS P C S
Sbjct: 556 QKAITCQKNNQ----WSAKKPGCVFS 577
Score = 44.7 bits (104), Expect = 5e-04
Identities = 66/282 (23%), Positives = 100/282 (35%), Gaps = 46/282 (16%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C P + NG G F G++V Y C+ GF+L G L C + S+ +W P P
Sbjct: 139 CGNPGRLPNGIQQG---STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTH--SAYSHN---------------DIVYVDCNPGFI 880
C C ++ H S Y +N +V++D
Sbjct: 196 CRAD---DACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG 252
Query: 881 MNGSRVIRCHTDNTWVPG----VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 936
+ V + W G P K ++ T +GNH G S
Sbjct: 253 YDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRL---HFTSDGNHR-------QRGFSAQ 302
Query: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM---DGI-QKGLEPRKMYQY 992
Y + L + L + SQ +V S +M GI ++G ++
Sbjct: 303 YQVKKQIELKSRGVKLMPSKDN-SQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRL 361
Query: 993 GAVVTLECEDGYMLEGSPQSQCQ--SD--HQWNPPLAVCRSR 1030
G+ V C +GY L+GS + C SD W+ VCR+R
Sbjct: 362 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
Score = 43.9 bits (102), Expect = 8e-04
Identities = 54/222 (24%), Positives = 81/222 (36%), Gaps = 47/222 (21%)
Query: 233 RVGVTANFFCDEGYRLQGPPSSRCV-IAGQGVAWT-KMPVCEEIFCPS----PPPILNGR 286
R+G + F C+EGY LQG C+ ++ AW+ PVC C + P I+
Sbjct: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
Query: 287 HIGNSLANVSYGSIVTYTCDP-----------DPEEGVNFILIGESTL---RCTVDSQKT 332
+ N ++ + +P D E G + + +G+ + TV T
Sbjct: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
Query: 333 GT-------------W-------SGPAPRCELSTSAVQ---CPHPQI-LRGRMVSGQKDR 368
GT W SG + + S ++ C P I GR + R
Sbjct: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRR---EGSR 536
Query: 369 YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
+ + DT+ F C F L G K I C W P C C
Sbjct: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSC 578
Score = 40.8 bits (94), Expect = 0.007
Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
+CG+P + NG I ST +G +RYSC+ F L G L C + TWD P P
Sbjct: 138 TCGNPGRLPNG-IQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
Query: 82 C 82
C
Sbjct: 196 C 196
Score = 39.3 bits (90), Expect = 0.021
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Query: 964 PHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWN 1021
P C+ D + G+ Y G VT EC GY L G P CQ ++ W+
Sbjct: 2113 PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWD 2172
Query: 1022 PPLAVC 1027
PL C
Sbjct: 2173 HPLPKC 2178
Score = 35.8 bits (81), Expect = 0.23
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 88 YSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC 132
++ CP+P +P K GS +R G SV F C + + G+K + C
Sbjct: 340 HNMCPDPGIPERGKRLGSD-FRLGSSVQFTCNEGYDLQGSKRITC 383
Score = 34.3 bits (77), Expect = 0.66
Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 7/68 (10%)
Query: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE----GTWSQPAPH 965
CP P G G + F G S+ ++C++GY L G + C WS P
Sbjct: 343 CPDPGIPERGKRLGSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPV 399
Query: 966 CKEVNCSS 973
C+ C +
Sbjct: 400 CRARMCDA 407
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ--SDHQWNPPL 1024
K V SS + G++ + Y VV+ +CE GY L+G C + +WN P
Sbjct: 1902 KTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
Query: 1025 AVC 1027
+C
Sbjct: 1962 PLC 1964
Score = 32.7 bits (73), Expect = 1.9
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 843 PVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDN----TWVP 897
P C NP + +G + T ++ D V CN GF + G V+ CH + TW
Sbjct: 135 PSHTCGNPGRLPNGIQQGST---FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDF 191
Query: 898 GVPTC 902
+P+C
Sbjct: 192 PLPSC 196
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 269 bits (687), Expect = 1e-71
Identities = 177/510 (34%), Positives = 242/510 (47%), Gaps = 59/510 (11%)
Query: 429 FDPGTSIKYSCNPGYVLVGEE-SIQCTSEGVWTPPVPQCKVAACE-----ATGRQLLTKP 482
F GT + Y C PGY G SI C VWT +CK +C G + K
Sbjct: 55 FPIGTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIK- 111
Query: 483 QHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITCPPPPVIYNGAHT 539
QF R + SC +GY+L GS C T+ W + +C I C PP I NG T
Sbjct: 112 DIQF-RSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFT 170
Query: 540 GSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLA 599
S E F YG+ VTY CN G F L+GE +I CTS D + G WSGPAP C ++
Sbjct: 171 SISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC---IIP 227
Query: 600 VQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK 659
+C+ ++ NG +S + + N+ V F+C GF +KG S ++C+A N W+PE+P C +
Sbjct: 228 NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR 287
Query: 660 GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE- 718
CQ PP + H T + F G V Y+C+PGY L G+ +HC P G+WSP+APRCE
Sbjct: 288 VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEV 347
Query: 719 ETCQ---------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA-ENGIWFK 768
++C HV L L G++V+ V C +G+QL G + C A +W
Sbjct: 348 KSCDDFLGQLPNGHVLFPL-NLQLGAKVDFV---CDEGFQLKGSSASYCVLAGMESLWNS 403
Query: 769 KIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC-RSDSKG 827
+P+C+ C PPV VNG + + G+ ++Y C G L+G +C S +
Sbjct: 404 SVPVCERKSCETPPVPVNG--MVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTA 461
Query: 828 HGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVY-----VDCNP----- 877
H WS P C + CPNP LN H+ DI Y C+P
Sbjct: 462 H--WSMKPPICQQ----IFCPNPPA----ILNGRHTGTPLGDIPYGKEVSYTCDPHPDRG 511
Query: 878 -GFIMNGSRVIR----CHTDNTWVPGVPTC 902
F + G IR H + W P C
Sbjct: 512 MTFNLIGESTIRRTSEPHGNGVWSSPAPRC 541
Score = 248 bits (634), Expect = 2e-65
Identities = 156/503 (31%), Positives = 227/503 (45%), Gaps = 38/503 (7%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
G + Y C GY II CL + W++ C+ C++ NG ++
Sbjct: 58 GTYLNYECRPGYSGRPFSII-CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFR 116
Query: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
+ C +GYRL G S+ C+I+G V W K PVC+ I C PP I NG S
Sbjct: 117 SQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREY 176
Query: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
YGS+VTY C+ F L+GE ++ CT + G WSGPAP+C + +C P
Sbjct: 177 FHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPN---KCTPP 233
Query: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
+ G +VS + ++ N+ V F C GF +KG ++C A WEP P C + CQ PP
Sbjct: 234 NVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPP 293
Query: 415 NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEAT 474
++L+ ++ R F PG + YSC PGY L G + CT +G W+P P+C+V +C+
Sbjct: 294 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDF 353
Query: 475 GRQL----LTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITC 527
QL + P + + V+ C EG++L GS C W + +C+ +C
Sbjct: 354 LGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSC 413
Query: 528 PPPPVIYNG-AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
PPV NG H + D G+ + Y+C G LIG S+ C + W
Sbjct: 414 ETPPVPVNGMVHV---ITDIHVGSRINYSCTTG------HRLIGHSSAECILSG-NTAHW 463
Query: 587 SGPAPLCKLSLLAVQCSH-VHIANGYKISGKEAPYFYNDTVTFKC------YSGFTLKGS 639
S P+C+ + C + I NG Y V++ C F L G
Sbjct: 464 SMKPPICQ----QIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGE 519
Query: 640 SQIRCKAD----NTWDPEIPVCE 658
S IR ++ W P CE
Sbjct: 520 STIRRTSEPHGNGVWSSPAPRCE 542
Score = 209 bits (533), Expect = 9e-54
Identities = 138/400 (34%), Positives = 182/400 (45%), Gaps = 80/400 (20%)
Query: 21 ISCGSPPPILNGRISYYSTP-IAVGTVIRYSCS------GTFRLIGEKSLLCITKDKVDG 73
I CG PP I NG + S G+V+ Y C+ F L+GE S+ C +KD G
Sbjct: 156 IICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVG 215
Query: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGS-TPYRHGDSVTFACKTNFSMNGNKSVWC 132
W PAP+C NK C P V G + + + + + V F C+ F M G V C
Sbjct: 216 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
QA N W P LP+C V C P + + T + + +PG V YSCE GY L G
Sbjct: 273 QALNKWEP-ELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
++C G WS P CE C LG+ PNG V P L++G +F CDEG++L+G
Sbjct: 328 TYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGS 387
Query: 252 PSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNG----------------------RHI 288
+S CV+AG W + +PVCE C +PP +NG R I
Sbjct: 388 SASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLI 447
Query: 289 GNSLA------NVSYGSI----------------------------------VTYTCDPD 308
G+S A N ++ S+ V+YTCDP
Sbjct: 448 GHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPH 507
Query: 309 PEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSA 348
P+ G+ F LIGEST+R T + G WS PAPRCEL A
Sbjct: 508 PDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVGA 547
Score = 202 bits (513), Expect = 2e-51
Identities = 128/391 (32%), Positives = 188/391 (48%), Gaps = 33/391 (8%)
Query: 661 CQSPPGLHHGRHTGGNTVF-FVSGMTVDYTCDPGYLLVGNK-SIHCMPSGNWSPSAPRCE 718
C P L R T F F G ++Y C PGY G SI C+ + W+ + +C+
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCK 92
Query: 719 -ETCQH-------VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENG-IWFKK 769
++C++ + ++++ S+++ SC GY+L G + C + N IW K
Sbjct: 93 RKSCRNPPDPVNGMAHVIKDIQFRSQIKY---SCPKGYRLIGSSSATCIISGNTVIWDNK 149
Query: 770 IPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG------FYLLGEKKLQCRS 823
P+C I C PP I NG T + E F YG+ V+Y C+ G F L+GE + C S
Sbjct: 150 TPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTS 209
Query: 824 DSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG 883
G WSGP+PQC+ +C P V++G ++ S +S N++V C PGF M G
Sbjct: 210 KDDQVGIWSGPAPQCIIP---NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKG 266
Query: 884 SRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY 943
++C N W P +P+C + C PPP + T + FSPG + YSC+ GY
Sbjct: 267 PSHVKCQALNKWEPELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 322
Query: 944 LLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG 1003
L G L CT +G WS AP C+ +C L P + Q GA V C++G
Sbjct: 323 DLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNL-QLGAKVDFVCDEG 381
Query: 1004 YMLEGSPQSQC---QSDHQWNPPLAVCRSRS 1031
+ L+GS S C + WN + VC +S
Sbjct: 382 FQLKGSSASYCVLAGMESLWNSSVPVCERKS 412
Score = 151 bits (382), Expect = 3e-36
Identities = 141/488 (28%), Positives = 204/488 (41%), Gaps = 67/488 (13%)
Query: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
+FP GT + Y C PG G FS+I C N W+ CK
Sbjct: 54 EFPIGTYLNYECRPG-YSGRPFSII------CLKN----SVWTSAKDKCKRKSCRNPPDP 102
Query: 605 VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC-KADNT--WDPEIPVCEK-G 660
V NG K+ + + + C G+ L GSS C + NT WD + PVC++
Sbjct: 103 V---NGMAHVIKDIQ--FRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRII 157
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNKSIHCMPS----GNW 710
C PP + +G T + +F G V Y C+ G + LVG SI+C G W
Sbjct: 158 CGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIW 217
Query: 711 SPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQLTGHAYQMCQDAEN 763
S AP+C C L + +R E+V CQ G+ + G ++ CQ
Sbjct: 218 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNK 277
Query: 764 GIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRS 823
W ++P C + C PPP +++ + T +NF G EV Y C+ G+ L G L C
Sbjct: 278 --WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTP 334
Query: 824 DSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 881
G WS +P+C V C + ++ +G+ L + V C+ GF +
Sbjct: 335 ----QGDWSPAAPRC----EVKSCDDFLGQLPNGHVLFPLNLQLGAK--VDFVCDEGFQL 384
Query: 882 NGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGN-HTGGNIARFSPGMSILY 937
GS C ++ W VP C +K+ C PP NG H I G I Y
Sbjct: 385 KGSSASYCVLAGMESLWNSSVPVCERKS---CETPPVPVNGMVHV---ITDIHVGSRINY 438
Query: 938 SCDQGYLLVGEALLLCTHEGT---WSQPAPHCKEVNC-SSPADMDGIQKGLEPRKMYQYG 993
SC G+ L+G + C G WS P C+++ C + PA ++G G P YG
Sbjct: 439 SCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTG-TPLGDIPYG 497
Query: 994 AVVTLECE 1001
V+ C+
Sbjct: 498 KEVSYTCD 505
Score = 150 bits (379), Expect = 6e-36
Identities = 137/510 (26%), Positives = 193/510 (37%), Gaps = 61/510 (11%)
Query: 491 VNSSCGEGYKLSGSVYQE-CQGTIPWFMEIRLCKEITCPPPPVIYNG-AHTGSSLEDFPY 548
+N C GY SG + C W CK +C PP NG AH ++D +
Sbjct: 61 LNYECRPGY--SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHV---IKDIQF 115
Query: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIA 608
+ + Y+C G + LIG S+ C + W P+C + + + IA
Sbjct: 116 RSQIKYSCPKG------YRLIGSSSATCIISGNTV-IWDNKTPVCDRIICGLPPT---IA 165
Query: 609 NGYKISGKEAPYFYNDTVTFKCYSG------FTLKGSSQIRCKADNT----WDPEIPVC- 657
NG S + Y VT+ C G F L G I C + + W P C
Sbjct: 166 NGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCI 225
Query: 658 -EKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPR 716
C +PP + +G N F V++ C PG+ + G + C W P P
Sbjct: 226 IPNKC-TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPS 284
Query: 717 CEETCQ------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKI 770
C CQ H ++ ++ S + V SC+ GY L G Y C G W
Sbjct: 285 CSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHC--TPQGDWSPAA 342
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS 830
P C+V C + H + N G +V + CD+GF L G C
Sbjct: 343 PRCEVKSCDDFLGQLPNGHV-LFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM-ESL 400
Query: 831 WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 890
W+ P C R C P V ++ + + I Y C G + G C
Sbjct: 401 WNSSVPVCERKS----CETPPVPVNGMVHVITDIHVGSRINY-SCTTGHRLIGHSSAECI 455
Query: 891 -TDNT--WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCD------Q 941
+ NT W P C + I CP PP NG HTG + G + Y+CD
Sbjct: 456 LSGNTAHWSMKPPICQQ---IFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGM 512
Query: 942 GYLLVGEALLLCTHE----GTWSQPAPHCK 967
+ L+GE+ + T E G WS PAP C+
Sbjct: 513 TFNLIGESTIRRTSEPHGNGVWSSPAPRCE 542
Score = 92.0 bits (227), Expect = 3e-18
Identities = 79/326 (24%), Positives = 125/326 (38%), Gaps = 26/326 (7%)
Query: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
E P G+ +N C+ GY +G + + +N +W CK C PP VNG
Sbjct: 54 EFPIGT---YLNYECRPGY--SGRPFSIIC-LKNSVWTSAKDKCKRKSCRNPPDPVNGM- 106
Query: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN 849
+ ++ + +++ Y C +G+ L+G C S W +P C R + P
Sbjct: 107 -AHVIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWDNKTPVCDRI--ICGLP- 161
Query: 850 PEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WVPGV 899
P + +G + + + + +V CN G F + G I C + + W
Sbjct: 162 PTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPA 221
Query: 900 PTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTW 959
P CI PP NG N + FS + + C G+ + G + + C W
Sbjct: 222 PQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKW 278
Query: 960 SQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQ 1019
P C V C P D+ ++ + + G V CE GY L GS C
Sbjct: 279 EPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGD 337
Query: 1020 WNPPLAVCRSRSLAPVLCGIAAGLIL 1045
W+P C +S L + G +L
Sbjct: 338 WSPAAPRCEVKSCDDFLGQLPNGHVL 363
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 248 bits (634), Expect = 2e-65
Identities = 167/514 (32%), Positives = 239/514 (46%), Gaps = 67/514 (13%)
Query: 176 GLSVTYSCESGYLLV-GEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV 234
G ++ Y+C GY+ + + C S G+W C RC+ G NG+V+ L
Sbjct: 74 GTTLKYTCLPGYVRSHSTQTLTCNSDGEW-VYNTFCIYKRCRHPGELRNGQVEIKTDLSF 132
Query: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLA 293
G F C EG+ L G +SRC + +GV W+ +P CE + C PP I NGRH G
Sbjct: 133 GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENF 192
Query: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
+YG VTY+CDP F L+G +++ CTV+++ G W P CE T C
Sbjct: 193 -YAYGFSVTYSCDP------RFSLLGHASISCTVENETIGVWRPSPPTCEKIT----CRK 241
Query: 354 PQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQA 412
P + G MVSG Y Y DT++F C GF L+GS I C+A W PS P CE C
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCIN 301
Query: 413 PPNILNGQ--------KEDRHMVRFDPGTSIKYSCNPGYVLVGEE--SIQCTSEGVWTPP 462
P+I + KED ++V GT ++Y C+PGY +E ++ C WT P
Sbjct: 302 LPDIPHASWETYPRPTKEDVYVV----GTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 356
Query: 463 VPQCKVAACEATGRQLLTKPQHQFVRP----------DVNSSCGEGYKLSGSVYQECQGT 512
C+ C QH+ RP +++ SC E + S CQG
Sbjct: 357 YQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAI----CQGD 412
Query: 513 IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
W C +I C PP I +G + SS F + + Y C+ G + L+G++
Sbjct: 413 GTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSF-FKEEIIYECDKG------YILVGQA 464
Query: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS 632
+ C+ + WS PAP CK C + NG ++S + Y + VT +C S
Sbjct: 465 KLSCSYSH-----WSAPAPQCK-----ALCRKPELVNG-RLSVDKDQYVEPENVTIQCDS 513
Query: 633 GFTLKGSSQIRCKADNTWDPEIPVCE----KGCQ 662
G+ + G I C + TW PE+P CE +GC+
Sbjct: 514 GYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCE 547
Score = 234 bits (597), Expect = 3e-61
Identities = 162/534 (30%), Positives = 240/534 (44%), Gaps = 58/534 (10%)
Query: 404 PVCEKECQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLV-GEESIQCTSEGVWT 460
P C PP + D + RF GT++KY+C PGYV +++ C S+G W
Sbjct: 44 PAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV 103
Query: 461 PPVPQCKVAACEATGR----QLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGT---I 513
C C G Q+ K F + SC EG+ L GS C+ +
Sbjct: 104 YNT-FCIYKRCRHPGELRNGQVEIKTDLSF-GSQIEFSCSEGFFLIGSTTSRCEVQDRGV 161
Query: 514 PWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGEST 573
W + C+ + C PPP I NG H+G + YG +VTY+C+P FSL+G ++
Sbjct: 162 GWSHPLPQCEIVKCKPPPDIRNGRHSGEE-NFYAYGFSVTYSCDP------RFSLLGHAS 214
Query: 574 IRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSG 633
I CT ++ G W P C+ + C +++G +SG Y Y DT+ FKC G
Sbjct: 215 ISCTVENETIGVWRPSPPTCE----KITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKG 270
Query: 634 FTLKGSSQIRCKADNTWDPEIPVCE-KGCQSPPGLHHG------RHTGGNTVFFVSGMTV 686
F L+GSS I C AD+ W+P P CE C + P + H R T + +V G +
Sbjct: 271 FVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDV--YVVGTVL 328
Query: 687 DYTCDPGYLLVGNK--SIHCMPSGNWSPSAPRCEETC--------QHVRQSLQELPAGSR 736
Y C PGY ++ ++ C + W+P CE C + Q + PA
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CEALCCPEPKLNNGEITQHRKSRPANHC 387
Query: 737 VELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 796
V T +CQ +G W + P C I C+ PP I +G + + +
Sbjct: 388 VYFYGDEISFSCHETSRFSAICQG--DGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYS 444
Query: 797 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
F + E+ YECD+G+ L+G+ KL C + WS P+PQC C PE+ +G
Sbjct: 445 F-FKEEIIYECDKGYILVGQAKLSC-----SYSHWSAPAPQCK-----ALCRKPELVNG- 492
Query: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 910
+L+ Y + V + C+ G+ + G + I C + TW P VP C + GC
Sbjct: 493 RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGC 546
Score = 172 bits (437), Expect = 1e-42
Identities = 159/546 (29%), Positives = 224/546 (41%), Gaps = 78/546 (14%)
Query: 11 LALVAPGVLGISCGSPPPILNGR---ISYYSTPIAVGTVIRYSC-SGTFRLIGEKSLLCI 66
+A + P VLG +CG PP + I+ T GT ++Y+C G R ++L C
Sbjct: 39 IAALLPAVLG-NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCN 97
Query: 67 TKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNG 126
+ DG W F Y C P ++ T G + F+C F + G
Sbjct: 98 S----DGEW-----VYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIG 148
Query: 127 NKSVWCQANNM---WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSC 183
+ + C+ + W LP C V +C P I NG H+ E A G SVTYSC
Sbjct: 149 STTSRCEVQDRGVGWSHP-LPQCEIV---KCKPPPDIRNGRHSGEE-NFYAYGFSVTYSC 203
Query: 184 ESGYLLVGEKIINCL----SSGKWSAVPPTCEEARCK----SLGRFPNGKVKEPPILRVG 235
+ + L+G I+C + G W PPTCE+ C+ S G +G PI
Sbjct: 204 DPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSG---FGPIYNYK 260
Query: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNG------RHI 288
T F C +G+ L+G C + W P CE C + P I + R
Sbjct: 261 DTIVFKCQKGFVLRGSSVIHCDADSK---WNPSPPACEPNSCINLPDIPHASWETYPRPT 317
Query: 289 GNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSA 348
+ V G+++ Y C P + + E T TV QK W+ P CE A
Sbjct: 318 KEDVYVV--GTVLRYRCHPGYKPTTD-----EPT---TVICQKNLRWT-PYQGCE----A 362
Query: 349 VQCPHPQILRGRMVSGQKDR------YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPS 402
+ CP P++ G + +K R Y Y D + F+C C GTW P
Sbjct: 363 LCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAI----CQGDGTWSPR 418
Query: 403 APVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPP 462
P C C PP I +G + F I Y C+ GY+LVG+ + C S W+ P
Sbjct: 419 TPSCGDICNFPPKIAHGHYKQSSSYSFFK-EEIIYECDKGYILVGQAKLSC-SYSHWSAP 476
Query: 463 VPQCKVAACE----ATGRQLLTKPQHQFVRPD-VNSSCGEGYKLSGSVYQECQGTIPWFM 517
PQCK A C GR L+ + Q+V P+ V C GY + G C G W+
Sbjct: 477 APQCK-ALCRKPELVNGR--LSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYP 533
Query: 518 EIRLCK 523
E+ C+
Sbjct: 534 EVPKCE 539
Score = 171 bits (432), Expect = 5e-42
Identities = 144/529 (27%), Positives = 228/529 (43%), Gaps = 68/529 (12%)
Query: 527 CPPPPVIYNGAHTGSSLED--FPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
C PPP + A +L + F GTT+ YTC PG R T+ C S+ G
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHS-----TQTLTCNSD----G 100
Query: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
W + + +C H ++ K + + F C GF L GS+ RC
Sbjct: 101 EW-----VYNTFCIYKRCRHPGELRNGQVEIK-TDLSFGSQIEFSCSEGFFLIGSTTSRC 154
Query: 645 KADNT---WDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNK 700
+ + W +P CE C+ PP + +GRH+G F+ G +V Y+CDP + L+G+
Sbjct: 155 EVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEEN-FYAYGFSVTYSCDPRFSLLGHA 213
Query: 701 SIHCMPS----GNWSPSAPRCEE-TCQHVRQSLQELPAG-----SRVELVNTSCQDGYQL 750
SI C G W PS P CE+ TC+ S E+ +G + + + CQ G+ L
Sbjct: 214 SISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVL 273
Query: 751 TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGM----MAENFLYGNEVSYE 806
G + C DA++ W P C+ C P I + + ++ G + Y
Sbjct: 274 RGSSVIHC-DADSK-WNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYR 331
Query: 807 CDQGFYLLGEKKLQ--CRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHG----YKLNK 860
C G+ ++ C+ + + W+ P C CP P++ +G ++ ++
Sbjct: 332 CHPGYKPTTDEPTTVICQKNLR----WT-PYQGC----EALCCPEPKLNNGEITQHRKSR 382
Query: 861 --THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPN 918
H Y + D + C+ + C D TW P P+C C PPK +
Sbjct: 383 PANHCVYFYGDEISFSCHETSRFSAI----CQGDGTWSPRTPSCGDI----CNFPPKIAH 434
Query: 919 GNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMD 978
G++ + F I+Y CD+GY+LVG+A L C++ WS PAP CK + C P ++
Sbjct: 435 GHYKQSSSYSFFKE-EIIYECDKGYILVGQAKLSCSYSH-WSAPAPQCKAL-CRKPELVN 491
Query: 979 GIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 1027
G + + Y VT++C+ GY + G C + W P + C
Sbjct: 492 G--RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 168 bits (425), Expect = 3e-41
Identities = 137/506 (27%), Positives = 214/506 (42%), Gaps = 59/506 (11%)
Query: 23 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 82
C P + NG++ T ++ G+ I +SCS F LIG + C +D+ G W P P+C
Sbjct: 113 CRHPGELRNGQVEI-KTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG-WSHPLPQC 170
Query: 83 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANN----MW 138
E P P + G Y +G SVT++C FS+ G+ S+ C N +W
Sbjct: 171 EI---VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 139 GPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGL----SVTYSCESGYLLVGEKI 194
P+ PTC + C + H E V P ++ + C+ G++L G +
Sbjct: 228 RPSP-PTCEKI---TCRKPDVSH-----GEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSV 278
Query: 195 INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPP------ILRVGVTANFFCDEGYRL 248
I+C + KW+ PP CE C +L P+ + P + VG + C GY+
Sbjct: 279 IHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYK- 337
Query: 249 QGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNG---RHIGNSLAN---VSYGSIVT 302
VI + + WT CE + CP P + NG +H + AN YG ++
Sbjct: 338 PTTDEPTTVICQKNLRWTPYQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEIS 396
Query: 303 YTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMV 362
++C T R + Q GTWS P C P P+I G
Sbjct: 397 FSC--------------HETSRFSAICQGDGTWSPRTPSC---GDICNFP-PKIAHGHYK 438
Query: 363 SGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKE 422
+ + + +I+ C G+ L G ++ C + W AP C+ C+ P ++NG+
Sbjct: 439 QSSSYSF-FKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCKALCR-KPELVNGRLS 495
Query: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKP 482
+P ++ C+ GY +VG +SI C+ W P VP+C+ E + L K
Sbjct: 496 VDKDQYVEP-ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKR 554
Query: 483 QHQFV-RPDVNSSCGEGYKLSGSVYQ 507
Q + P+ E YKLS + Q
Sbjct: 555 LMQCLPNPEDVKMALEVYKLSLEIEQ 580
Score = 152 bits (384), Expect = 2e-36
Identities = 131/496 (26%), Positives = 201/496 (40%), Gaps = 58/496 (11%)
Query: 494 SCGEGYKLSGSVYQ-ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTV 552
+C GY S S C W C C P + NG + D +G+ +
Sbjct: 80 TCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRNGQVEIKT--DLSFGSQI 136
Query: 553 TYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYK 612
++C+ G F LIG +T RC D+ G WS P P C++ V+C +
Sbjct: 137 EFSCSEG------FFLIGSTTSRCEVQDRGVG-WSHPLPQCEI----VKCKPPPDIRNGR 185
Query: 613 ISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN----TWDPEIPVCEKGCQSPPGLH 668
SG+E Y Y +VT+ C F+L G + I C +N W P P CEK P +
Sbjct: 186 HSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVS 245
Query: 669 HGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETC------ 721
HG G + T+ + C G++L G+ IHC W+PS P CE +C
Sbjct: 246 HGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDI 305
Query: 722 QHVRQSLQELPAGSRVELVNT----SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIH 777
H P V +V T C GY+ T +N W C+ +
Sbjct: 306 PHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRW-TPYQGCEAL- 363
Query: 778 CHPPPVIVNGKHTGMMAEN------FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 831
C P P + NG+ T + YG+E+S+ C + + + +G G+W
Sbjct: 364 CCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSC--------HETSRFSAICQGDGTW 415
Query: 832 SGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHT 891
S +P C + P P++ HG+ + ++ +I+Y +C+ G+I+ G + C
Sbjct: 416 SPRTPSC---GDICNFP-PKIAHGHYKQSSSYSFFKEEIIY-ECDKGYILVGQAKLSCSY 470
Query: 892 DNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALL 951
+ W P C KA P+ NG + P ++ CD GY +VG +
Sbjct: 471 SH-WSAPAPQC--KALC---RKPELVNGRLSVDKDQYVEP-ENVTIQCDSGYGVVGPQSI 523
Query: 952 LCTHEGTWSQPAPHCK 967
C+ TW P C+
Sbjct: 524 TCSGNRTWYPEVPKCE 539
Score = 151 bits (381), Expect = 4e-36
Identities = 115/413 (27%), Positives = 180/413 (43%), Gaps = 43/413 (10%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
+ C PP I NGR S A G + YSC F L+G S+ C +++ G W P
Sbjct: 173 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 232
Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
CE +C +P V G + G P Y + D++ F C+ F + G+ + C A++ W
Sbjct: 233 TCEKI----TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWN 288
Query: 140 PTRLPTCVSVFPLECPALPMIHNG------HHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
P+ P C P C LP I + T E+V + G + Y C GY ++
Sbjct: 289 PSP-PACE---PNSCINLPDIPHASWETYPRPTKEDVYVV--GTVLRYRCHPGYKPTTDE 342
Query: 194 --IINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
+ C + +W+ P EA C + NG++ + R +F +
Sbjct: 343 PTTVICQKNLRWT--PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCH 400
Query: 252 PSSR--CVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDP 309
+SR + G G + P C +I C PP I +G H S + + + Y CD
Sbjct: 401 ETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHG-HYKQSSSYSFFKEEIIYECDK-- 456
Query: 310 EEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRY 369
+IL+G++ L C+ WS PAP+C+ C P+++ GR+ S KD+Y
Sbjct: 457 ----GYILVGQAKLSCSYSH-----WSAPAPQCK-----ALCRKPELVNGRL-SVDKDQY 501
Query: 370 TYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC-QAPPNILNGQK 421
+ V C G+ + G + I C+ TW P P CE E + +L G++
Sbjct: 502 VEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKR 554
Score = 107 bits (266), Expect = 8e-23
Identities = 76/267 (28%), Positives = 115/267 (43%), Gaps = 29/267 (10%)
Query: 777 HCHPPPVI--VNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEKKLQCRSDSKGHGSWSG 833
+C PPP + + F G + Y C G+ + L C SD G W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSD----GEWVY 104
Query: 834 PSPQCLRSPPVTRCPNP-EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTD 892
+ C+ RC +P E+++G KT ++ + C+ GF + GS RC
Sbjct: 105 -NTFCIYK----RCRHPGELRNGQVEIKTDLSFGSQ--IEFSCSEGFFLIGSTTSRCEVQ 157
Query: 893 NT---WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEA 949
+ W +P C + C PPP NG H+G ++ G S+ YSCD + L+G A
Sbjct: 158 DRGVGWSHPLPQC---EIVKCKPPPDIRNGRHSGEENF-YAYGFSVTYSCDPRFSLLGHA 213
Query: 950 LLLCTHE----GTWSQPAPHCKEVNCSSPADMDG-IQKGLEPRKMYQYGAVVTLECEDGY 1004
+ CT E G W P C+++ C P G + G P +Y Y + +C+ G+
Sbjct: 214 SISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGP--IYNYKDTIVFKCQKGF 271
Query: 1005 MLEGSPQSQCQSDHQWNPPLAVCRSRS 1031
+L GS C +D +WNP C S
Sbjct: 272 VLRGSSVIHCDADSKWNPSPPACEPNS 298
Score = 55.1 bits (131), Expect = 4e-07
Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Query: 20 GISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPA 79
G C PP I +G S+ I Y C + L+G+ L C W PA
Sbjct: 423 GDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH-----WSAPA 477
Query: 80 PKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWG 139
P+C+ + C +P + G Y ++VT C + + + G +S+ C N W
Sbjct: 478 PQCK-----ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWY 532
Query: 140 PTRLPTCVSVFPLEC 154
P +P C P C
Sbjct: 533 P-EVPKCEWETPEGC 546
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 226 bits (575), Expect = 1e-58
Identities = 262/1055 (24%), Positives = 426/1055 (40%), Gaps = 141/1055 (13%)
Query: 23 CGSPPPILNGRI---SYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWD--K 77
C PP N I S+ GT Y C +R +G ++C G W
Sbjct: 21 CNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-----GEWVALN 75
Query: 78 PAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNM 137
P KC+ + P G + + G + +G + C + + G + +
Sbjct: 76 PLRKCQ--KRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG 133
Query: 138 WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP---GLSVTYSCESGYLLVGEKI 194
W +P C V +C + NG S + G +V + C SGY + G++
Sbjct: 134 W-TNDIPICEVV---KCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEE 189
Query: 195 INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSS 254
++C G WS P C E CKS + + I + + C+ GY +
Sbjct: 190 MHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDA 249
Query: 255 RCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C +G W +P CEE C + P I NG + + + + G +TY C G
Sbjct: 250 VCTESG----WRPLPSCEEKSCDN-PYIPNGDYSPLRIKHRT-GDEITYQC----RNGFY 299
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
G +T +CT TG W PAPRC L C +P I G + R +
Sbjct: 300 PATRG-NTAKCT----STG-WI-PAPRCTLK----PCDYPDIKHGGLYHENMRRPYFPVA 348
Query: 375 V----IFACMFGF-TLKGS--KQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMV 427
V + C F T GS I C G W P+ P C ++C P + NG ++ H
Sbjct: 349 VGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP-CLRKCYF-PYLENGYNQN-HGR 404
Query: 428 RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC-KVAACEATGRQL----LTKP 482
+F G SI +C+PGY L ++ E W+ P P+C +V C + + +++
Sbjct: 405 KFVQGKSIDVACHPGYALPKAQTTVTCMENGWS-PTPRCIRVKTCSKSSIDIENGFISES 463
Query: 483 QHQF-VRPDVNSSCGEGY-----KLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNG 536
Q+ + ++ C GY + SGS+ C G W + K P ++
Sbjct: 464 QYTYALKEKAKYQCKLGYVTADGETSGSI--TC-GKDGWSAQPTCIKSCDIP----VFMN 516
Query: 537 AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGEST--IRCTSNDQERGTWSGPAPLCK 594
A T + F T+ Y C+ G E S G +T I C N WS P+C
Sbjct: 517 ARTKNDFTWFKLNDTLDYECHDGYE-----SNTGSTTGSIVCGYNG-----WS-DLPICY 565
Query: 595 LSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEI 654
+ VH+ K+ Y + + F C GFT+ G + ++C P++
Sbjct: 566 ERECELPKIDVHLVP----DRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDL 620
Query: 655 PVCE---KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWS 711
P+C+ + C PP L +G + V+Y C+P +L+ G I C+ G W+
Sbjct: 621 PICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT 679
Query: 712 PSAPRC---EETC------QHVRQSLQELP--AGSRVELVNTSCQDGYQLTGHAYQMCQD 760
+ P C E TC +H L P G VE +C + + + GH C
Sbjct: 680 -TLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEF---NCSESFTMIGHRSITC-- 733
Query: 761 AENGIWFKKIPLC----KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYEC--DQGFYLL 814
+G+W ++P C K+ C +I+ +H E F + + + Y C +G+
Sbjct: 734 -IHGVW-TQLPQCVAIDKLKKCKSSNLIILEEHLKNKKE-FDHNSNIRYRCRGKEGWI-- 788
Query: 815 GEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVD 874
C +G W P C + P P++ + + + T + Y + V V
Sbjct: 789 ---HTVCI-----NGRWD-PEVNCSMAQIQLCPPPPQIPNSHNMTTTLN-YRDGEKVSVL 838
Query: 875 CNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG--NHTGGNIARFSPG 932
C +++ I C D W +P C++K I C PP+ +G N + + ++ G
Sbjct: 839 CQENYLIQEGEEITC-KDGRW-QSIPLCVEK--IPCSQPPQIEHGTINSSRSSQESYAHG 894
Query: 933 MSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMD-GIQKGLEPRKMYQ 991
+ Y+C+ G+ + E C + G WS P P C+ + C SP ++ G+ + YQ
Sbjct: 895 TKLSYTCEGGFRISEENETTC-YMGKWSSP-PQCEGLPCKSPPEISHGVVAHMS--DSYQ 950
Query: 992 YGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAV 1026
YG VT +C +G+ ++G ++C + +PP +
Sbjct: 951 YGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCI 985
Score = 212 bits (539), Expect = 2e-54
Identities = 251/1084 (23%), Positives = 402/1084 (37%), Gaps = 198/1084 (18%)
Query: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIR 103
G +R+ C+ +++ G++ + C DG W K PKC SC P V G I
Sbjct: 171 GQAVRFVCNSGYKIEGDEEMHCSD----DGFWSKEKPKCVEI----SCKSPDVINGSPIS 222
Query: 104 GSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNG 163
Y+ + + C + + C + W P LP+C C P I NG
Sbjct: 223 QKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRP--LPSCEEK---SCDN-PYIPNG 275
Query: 164 HHTSENVGSIAPGLSVTYSCESG-YLLVGEKIINCLSSGKWSAVP----PTCEEARCKSL 218
++ + G +TY C +G Y C S+G W P C+ K
Sbjct: 276 DYSPLRIKH-RTGDEITYQCRNGFYPATRGNTAKCTSTG-WIPAPRCTLKPCDYPDIKHG 333
Query: 219 GRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPS 278
G + + + VG +++CDE + PS G W + ++ + P+
Sbjct: 334 GLYHENMRRPYFPVAVGKYYSYYCDEHFET---PS--------GSYWDHIHCTQDGWSPA 382
Query: 279 PP-------PILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQK 331
P P L + N G + C P + L T TV +
Sbjct: 383 VPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHP------GYALPKAQT---TVTCME 433
Query: 332 TGTWSGPAPRCELSTSAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTL---KG 387
G WS P PRC C I + +S + Y + + C G+ +
Sbjct: 434 NG-WS-PTPRC---IRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGET 488
Query: 388 SKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVL-V 446
S I C G W + P C K C P + K D F ++ Y C+ GY
Sbjct: 489 SGSITCGKDG-WS-AQPTCIKSCDIPVFMNARTKND--FTWFKLNDTLDYECHDGYESNT 544
Query: 447 GEE--SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS----SCGEGYK 500
G SI C G W+ +P C CE + P + + V SC G+
Sbjct: 545 GSTTGSIVCGYNG-WSD-LPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFT 602
Query: 501 LSGSVYQECQ--GTIPWFMEIRLCKEI--TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTC 556
+ G +C G P ++ +CKE +C PPP + NG + E++ + V Y C
Sbjct: 603 IVGPNSVQCYHFGLSP---DLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYC 659
Query: 557 NPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK 616
NP F + G + I+C G W+ P+C + C +
Sbjct: 660 NP------RFLMKGPNKIQCVD-----GEWT-TLPVCIVE--ESTCGDIPELEHGWAQLS 705
Query: 617 EAPYFYNDTVTFKCYSGFTLKGSSQI--------------------RCKADNT------- 649
PY+Y D+V F C FT+ G I +CK+ N
Sbjct: 706 SPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHL 765
Query: 650 -------------------------------WDPEIPVCEKG----CQSPPGLHHGRHTG 674
WDPE+ C C PP + + H
Sbjct: 766 KNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVN-CSMAQIQLCPPPPQIPNS-HNM 823
Query: 675 GNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-------------TC 721
T+ + G V C YL+ + I C G W S P C E T
Sbjct: 824 TTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRWQ-SIPLCVEKIPCSQPPQIEHGTI 881
Query: 722 QHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPP 781
R S + G+++ +C+ G++++ C G W P C+ + C P
Sbjct: 882 NSSRSSQESYAHGTKLSY---TCEGGFRISEENETTCY---MGKWSSP-PQCEGLPCKSP 934
Query: 782 PVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRS 841
P I +G M++++ YG EV+Y+C +GF + G +C + WS P P C+++
Sbjct: 935 PEISHGV-VAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEK-----WSHP-PSCIKT 987
Query: 842 PPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPT 901
++ P ++ + + Y + V C + M+G+ + C ++ W G PT
Sbjct: 988 DCLSL---PSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC-INSRWT-GRPT 1042
Query: 902 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQ 961
C + C PP N ++++ G + Y C Y + G+ ++C + G W++
Sbjct: 1043 CRDTS---CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWTE 1098
Query: 962 PAPHCKEVN--CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQ 1019
P P CK+ C P +D P +Y + V +C++ Y LEG+ + C++ Q
Sbjct: 1099 P-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNG-Q 1156
Query: 1020 WNPP 1023
W+ P
Sbjct: 1157 WSEP 1160
Score = 151 bits (381), Expect = 4e-36
Identities = 129/503 (25%), Positives = 199/503 (39%), Gaps = 87/503 (17%)
Query: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLL-----------CITKDK 70
+CG P + +G S P G + ++CS +F +IG +S+ C+ DK
Sbjct: 690 TCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDK 749
Query: 71 -------------------------------------------VDGTWDKPAPKCEYFNK 87
++G WD P C
Sbjct: 750 LKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD-PEVNCSMAQI 808
Query: 88 YSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCV 147
P P +P + + + YR G+ V+ C+ N+ + + + C+ + W +P CV
Sbjct: 809 QLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DGRW--QSIPLCV 865
Query: 148 SVFPLECPALPMIHNGHHTSENVG--SIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 205
P C P I +G S S A G ++Y+CE G+ + E C GKWS+
Sbjct: 866 EKIP--CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYM-GKWSS 922
Query: 206 VPPTCEEARCKSLGRFPNGKVKE-PPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVA 264
PP CE CKS +G V + G + C EG+ + GP ++C+ G
Sbjct: 923 -PPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL----GEK 977
Query: 265 WTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLR 324
W+ P C + C S P N +G G VTYTC + + G S +
Sbjct: 978 WSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTC------ATYYKMDGASNVT 1031
Query: 325 CTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFT 384
C ++S+ TG P C TS V P Q +VS Q +Y + V + C +
Sbjct: 1032 C-INSRWTGR-----PTCR-DTSCVNPPTVQ--NAYIVSRQMSKYPSGERVRYQCRSPYE 1082
Query: 385 LKGSKQIRC-NAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGY 443
+ G +++ C N T P +C PP I NG + + P +S++Y C Y
Sbjct: 1083 MFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLY 1142
Query: 444 VLVGEESIQCTSEGVWTPPVPQC 466
L G + I C + G W+ P P+C
Sbjct: 1143 QLEGNKRITCRN-GQWSEP-PKC 1163
Score = 84.3 bits (207), Expect = 6e-16
Identities = 109/446 (24%), Positives = 167/446 (37%), Gaps = 64/446 (14%)
Query: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRH-------TGGNTVFF 680
+KC G+ G+ + C+ W P+ + CQ P H G TGGN F
Sbjct: 50 YKCRPGYRSLGNVIMVCRKGE-WVALNPL--RKCQKRPCGHPGDTPFGTFTLTGGNV--F 104
Query: 681 VSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE----------ETCQHVRQSLQ- 729
G+ YTC+ GY L+G + + W+ P CE E + V +++
Sbjct: 105 EYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEP 164
Query: 730 --ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNG 787
E G V V C GY++ G C D +G W K+ P C I C P VI NG
Sbjct: 165 DREYHFGQAVRFV---CNSGYKIEGDEEMHCSD--DGFWSKEKPKCVEISCKSPDVI-NG 218
Query: 788 KHTGMMAENFLY--GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
+++ +Y Y+C+ G+ + R D+ S P P C
Sbjct: 219 SP---ISQKIIYKENERFQYKCNMGY------EYSERGDAVCTESGWRPLPSCEEKS--- 266
Query: 846 RCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFI-MNGSRVIRCHTDNTWVPGVPTCIK 904
C NP + +G + + D + C GF +C T W+P P C
Sbjct: 267 -CDNPYIPNG-DYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKC-TSTGWIPA-PRCTL 322
Query: 905 KAFIGCPPPPKTPNGNHTGGNIARFSP---GMSILYSCDQGYLLVGEAL---LLCTHEGT 958
K C P G + + P G Y CD+ + + + CT +G
Sbjct: 323 KP---CDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 959 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 1018
WS P ++ C P +G + RK Q G + + C GY L + + ++
Sbjct: 379 WSPAVPCLRK--CYFPYLENGYNQN-HGRKFVQ-GKSIDVACHPGYALPKAQTTVTCMEN 434
Query: 1019 QWNPPLAVCRSRSLAPVLCGIAAGLI 1044
W+P R ++ + I G I
Sbjct: 435 GWSPTPRCIRVKTCSKSSIDIENGFI 460
Score = 74.7 bits (182), Expect = 4e-13
Identities = 64/213 (30%), Positives = 93/213 (43%), Gaps = 24/213 (11%)
Query: 44 GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEP-IVPGGYKI 102
G + Y+C+ +++ G ++ CI + W P C + +SC P V Y +
Sbjct: 1011 GEQVTYTCATYYKMDGASNVTCI-----NSRWTG-RPTC----RDTSCVNPPTVQNAYIV 1060
Query: 103 -RGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIH 161
R + Y G+ V + C++ + M G++ V C N W T P C +C P I
Sbjct: 1061 SRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNW--TEPPQCKDSTG-KCGPPPPID 1116
Query: 162 NGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRF 221
NG TS + AP SV Y C++ Y L G K I C +G+WS PP C S
Sbjct: 1117 NGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWSE-PPKCLHPCVISREIM 1174
Query: 222 PNGKV------KEPPILRVGVTANFFCDEGYRL 248
N + K+ R G + F C GYRL
Sbjct: 1175 ENYNIALRWTAKQKLYSRTGESVEFVCKRGYRL 1207
Score = 48.1 bits (113), Expect = 4e-05
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 5/110 (4%)
Query: 929 FSPGMSILYSCDQGYLLVGEALLLCTHEGTWS--QPAPHCKEVNCSSPADMDGIQKGLEP 986
+ G +Y C GY +G +++C +G W P C++ C P D L
Sbjct: 42 YPEGTQAIYKCRPGYRSLGNVIMVC-RKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTG 100
Query: 987 RKMYQYGAVVTLECEDGYMLEGS-PQSQCQSDHQWNPPLAVCRSRSLAPV 1035
+++YG C +GY L G +C +D W + +C PV
Sbjct: 101 GNVFEYGVKAVYTCNEGYQLLGEINYRECDTD-GWTNDIPICEVVKCLPV 149
Score = 47.8 bits (112), Expect = 6e-05
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 22/133 (16%)
Query: 23 CGSPPPILNGRISYYSTPI-AVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
CG PPPI NG I+ + + A + + Y C ++L G K + C +G W +P PK
Sbjct: 1109 CGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-----NGQWSEP-PK 1162
Query: 82 C--------EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
C E Y+ + + + R G+SV F CK + ++ ++S +
Sbjct: 1163 CLHPCVISREIMENYN------IALRWTAKQKLYSRTGESVEFVCKRGYRLS-SRSHTLR 1215
Query: 134 ANNMWGPTRLPTC 146
G PTC
Sbjct: 1216 TTCWDGKLEYPTC 1228
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 218 bits (556), Expect = 2e-56
Identities = 175/619 (28%), Positives = 258/619 (41%), Gaps = 84/619 (13%)
Query: 80 PKCEYFNKYSSCPEPIVPGGYKIRGSTP---YRHGDSVTFACKTNFSMNGNKSVWCQANN 136
P+CEY + C E +P + S P + +F C + +NG + C A+
Sbjct: 192 PECEYVRE---CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASG 248
Query: 137 MWGPTRLPTCVSVFPLECPALPMIHNGHHTS-ENVGSIAPGLSVTYSCESGYLLVGEKII 195
+W + P C++ +CP L + G+ T + + S ++SCE G+ LVG +++
Sbjct: 249 IW-TNKPPQCLAA---QCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVV 304
Query: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGK---VKEPPILRVGVTANFFCDEGYRLQGPP 252
C +SG W+A P C+ +C+ L G V G + F C GYR++G
Sbjct: 305 QCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLD 364
Query: 253 SSRCVIAGQGVAWTKMPVCEEIFC-PSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEE 311
RC+ +G A +P CE I C P P+ SL Y + ++ C E
Sbjct: 365 MLRCIDSGHWSA--PLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRC----AE 418
Query: 312 GVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQC---PHPQILRGRMVSGQKDR 368
G F+L G +RC G W+ PAP C+ A+QC P P R S
Sbjct: 419 G--FMLRGADIVRC----DNLGQWTAPAPVCQ----ALQCQDLPVPNEARVN-CSHPFGA 467
Query: 369 YTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP--NILNGQKEDRHM 426
+ Y F C G L G+ ++C A G W P ECQA P +L+ Q
Sbjct: 468 FRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPP----ECQAIPCTPLLSPQNGTMTC 523
Query: 427 VRFDPGTSIK----YSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC-----EATGRQ 477
V+ +S K + C+ GY L G E + CT G WT P C+ C G
Sbjct: 524 VQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSL 583
Query: 478 LLTKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPP----- 531
+ + +F V + SC G+KL G EC + W CK I P P
Sbjct: 584 DCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCP 643
Query: 532 --------VIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQER 583
+Y H G+ F + TT + CN G F+LIG+ST+ C +
Sbjct: 644 ALTTPGQGTMYCRHHPGT----FGFNTTCYFGCNAG------FTLIGDSTLSC----RPS 689
Query: 584 GTWSGPAPLCKLSLLAVQCSHVHIAN--GYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQ 641
G W+ P C+ AV+CS +H+ S + Y +F C G L GS+Q
Sbjct: 690 GQWTAVTPACR----AVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQ 745
Query: 642 IRCKADNTWDPEIPVCEKG 660
C+ + W +P C+ G
Sbjct: 746 TACQENGHWSTTVPTCQAG 764
Score = 203 bits (516), Expect = 8e-52
Identities = 166/595 (27%), Positives = 248/595 (41%), Gaps = 69/595 (11%)
Query: 167 SENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKV 226
S +G+ + ++ C GY + G + CL+SG W+ PP C A+C L G +
Sbjct: 214 SHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNM 273
Query: 227 K---EPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTK-MPVCEEIFCPS-PPP 281
+ + +F C+EG+ L GP +C +G WT PVC+ + C P
Sbjct: 274 TCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTAPAPVCKAVQCQHLEAP 330
Query: 282 ILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
+ L +YGS + C P + + G LRC +DS G WS P P
Sbjct: 331 SEGTMDCVHPLTAFAYGSSCKFECQP------GYRVRGLDMLRC-IDS---GHWSAPLPT 380
Query: 342 CELSTSAVQC-PHPQILRGRMVSGQKDR-YTYNDTVIFACMFGFTLKGSKQIRCNAQGTW 399
CE A+ C P + G M R + Y+ F C GF L+G+ +RC+ G W
Sbjct: 381 CE----AISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQW 436
Query: 400 EPSAPVCEK-ECQAPPNILNGQKEDRHMV-RFDPGTSIKYSCNPGYVLVGEESIQCTSEG 457
APVC+ +CQ P + H F + ++CN G +LVG +QC + G
Sbjct: 437 TAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATG 496
Query: 458 VWTPPVPQCKVAACEATGRQLLTKPQH---QFVRPDVNSS--------CGEGYKLSGSVY 506
W P+C+ C L PQ+ V+P +SS C EGY LSG
Sbjct: 497 NWNSVPPECQAIPCTP-----LLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPER 551
Query: 507 QECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLE-DFPYGTTVTYTCNPGPERGVE 565
+C + W +C+ I CP G+ S +F G+T ++C+ G
Sbjct: 552 LDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNG------ 605
Query: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCK----LSLLAVQCSHVHIANGYKISGKEAP-- 619
F L G + + CT++ G WS P CK L VQC + + + P
Sbjct: 606 FKLEGPNNVECTTS----GRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGT 661
Query: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVC------EKGCQSPPGLHHGRHT 673
+ +N T F C +GFTL G S + C+ W P C E P ++
Sbjct: 662 FGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLW 721
Query: 674 GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSL 728
G F G + C G LL G+ C +G+WS + P C+ ++++L
Sbjct: 722 GN----FSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEAL 772
Score = 199 bits (505), Expect = 2e-50
Identities = 160/599 (26%), Positives = 234/599 (39%), Gaps = 65/599 (10%)
Query: 340 PRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTW 399
P CE + PQ + S +++N F C G+ + G ++ C A G W
Sbjct: 192 PECEYVRECGELELPQHVLMNC-SHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIW 250
Query: 400 EPSAPVCEKECQAPPNIL--NGQKEDRHMVR-FDPGTSIKYSCNPGYVLVGEESIQCTSE 456
P C Q PP + G H + F +S +SC G+ LVG E +QCT+
Sbjct: 251 TNKPPQC-LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTAS 309
Query: 457 GVWTPPVPQCKVAACE-----ATGRQLLTKPQHQFV-RPDVNSSCGEGYKLSGSVYQECQ 510
GVWT P P CK C+ + G P F C GY++ G C
Sbjct: 310 GVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCI 369
Query: 511 GTIPWFMEIRLCKEITCPP-PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLI 569
+ W + C+ I+C P ++ SL F Y T ++ C G F L
Sbjct: 370 DSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEG------FMLR 423
Query: 570 GESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKI--SGKEAPYFYNDTVT 627
G +RC G W+ PAP+C+ A+QC + + N ++ S + Y +
Sbjct: 424 GADIVRC----DNLGQWTAPAPVCQ----ALQCQDLPVPNEARVNCSHPFGAFRYQSVCS 475
Query: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVS-GMT 685
F C G L G+S ++C A W+ P C+ C +G T + S T
Sbjct: 476 FTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKST 535
Query: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEE-TCQHVRQSLQ----------ELPAG 734
+ CD GY L G + + C SG W+ S P CE C + Q E G
Sbjct: 536 CQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVG 595
Query: 735 SRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP------PPVIVNGK 788
S SC +G++L G C +G W P CK I P P + G+
Sbjct: 596 STCHF---SCDNGFKLEGPNNVEC--TTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQ 650
Query: 789 HTGMMAEN---FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
T + F + + C+ GF L+G+ L CR G W+ +P C
Sbjct: 651 GTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPS----GQWTAVTPAC----RAV 702
Query: 846 RCPNPEVKHGYKLNKTH--SAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTC 902
+C V +N ++ +S+ I C G ++NGS C + W VPTC
Sbjct: 703 KCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 189 bits (480), Expect = 1e-47
Identities = 142/570 (24%), Positives = 233/570 (40%), Gaps = 65/570 (11%)
Query: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG-SSLEDFPYGTTVT 553
C +GY+++G EC + W + C CPP + G T S + F + ++ +
Sbjct: 230 CTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCS 289
Query: 554 YTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKI 613
++C G F+L+G ++CT++ G W+ PAP+CK AVQC H+ + +
Sbjct: 290 FSCEEG------FALVGPEVVQCTAS----GVWTAPAPVCK----AVQCQHLEAPSEGTM 335
Query: 614 SGKE--APYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEK-GCQSPPGLHHG 670
+ Y + F+C G+ ++G +RC W +P CE C+ HG
Sbjct: 336 DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHG 395
Query: 671 RHTGGNTV-FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQSL 728
++ F + C G++L G + C G W+ AP C+ CQ +
Sbjct: 396 SMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL---- 451
Query: 729 QELPAGSRVE------------LVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVI 776
+P +RV + + +C +G L G + C G W P C+ I
Sbjct: 452 -PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQC--LATGNWNSVPPECQAI 508
Query: 777 HCHPPPVIVNGKHTGMMA-ENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPS 835
C P NG T + + Y + + CD+G+ L G ++L C G W+
Sbjct: 509 PCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRS----GRWTDSP 564
Query: 836 PQCLRSPPVTRCPN---PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTD 892
P C +CP PE + + T ++ + C+ GF + G + C T
Sbjct: 565 PMC----EAIKCPELFAPE-QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTS 619
Query: 893 NTWVPGVPTCIKKAFIGCP----PPPKTPNGNHTGGNIARFSPGM-----SILYSCDQGY 943
W PTC A + P P TP G R PG + + C+ G+
Sbjct: 620 GRWSATPPTCKGIASLPTPGVQCPALTTPG---QGTMYCRHHPGTFGFNTTCYFGCNAGF 676
Query: 944 LLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPR-KMYQYGAVVTLECED 1002
L+G++ L C G W+ P C+ V CS I + YG++ + C +
Sbjct: 677 TLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLE 736
Query: 1003 GYMLEGSPQSQCQSDHQWNPPLAVCRSRSL 1032
G +L GS Q+ CQ + W+ + C++ L
Sbjct: 737 GQLLNGSAQTACQENGHWSTTVPTCQAGPL 766
Score = 161 bits (408), Expect = 3e-39
Identities = 113/433 (26%), Positives = 179/433 (41%), Gaps = 34/433 (7%)
Query: 620 YFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVF 679
+ +N +F C G+ + G S++ C A W + P C Q PP R G T
Sbjct: 220 FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC-LAAQCPPLKIPER--GNMTCL 276
Query: 680 -----FVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVR-------Q 726
F + ++C+ G+ LVG + + C SG W+ AP C+ CQH+
Sbjct: 277 HSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMD 336
Query: 727 SLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVN 786
+ L A + CQ GY++ G C D+ G W +P C+ I C P V+
Sbjct: 337 CVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDS--GHWSAPLPTCEAISCEPLESPVH 394
Query: 787 GK-HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
G F Y S+ C +GF L G ++C + G W+ P+P C
Sbjct: 395 GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN----LGQWTAPAPVC----QAL 446
Query: 846 RCPNPEVKHGYKLNKTH--SAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCI 903
+C + V + ++N +H A+ + + CN G ++ G+ V++C W P C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC- 505
Query: 904 KKAFIGCPPPPKTPNGNHTGGN-IARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQP 962
I C P NG T + S + + CD+GY L G L CT G W+
Sbjct: 506 --QAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 563
Query: 963 APHCKEVNCSSP-ADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 1021
P C+ + C A G + R + G+ C++G+ LEG +C + +W+
Sbjct: 564 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 623
Query: 1022 PPLAVCRSRSLAP 1034
C+ + P
Sbjct: 624 ATPPTCKGIASLP 636
Score = 159 bits (403), Expect = 1e-38
Identities = 131/505 (25%), Positives = 202/505 (40%), Gaps = 62/505 (12%)
Query: 49 YSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPGGYK---IRGS 105
+SC F L+G + + C G W PAP C K C P +
Sbjct: 290 FSCEEGFALVGPEVVQCTAS----GVWTAPAPVC----KAVQCQHLEAPSEGTMDCVHPL 341
Query: 106 TPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTC--VSVFPLECPALPMIHNG 163
T + +G S F C+ + + G + C + W LPTC +S PLE P +H
Sbjct: 342 TAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWS-APLPTCEAISCEPLESP----VHGS 396
Query: 164 HHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPN 223
S ++ + + ++ C G++L G I+ C + G+W+A P C+ +C+ L
Sbjct: 397 MDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNE 456
Query: 224 GKVK-EPPI--LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKM-PVCEEIFC-PS 278
+V P R +F C+EG L G +C+ G W + P C+ I C P
Sbjct: 457 ARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGN---WNSVPPECQAIPCTPL 513
Query: 279 PPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGP 338
P L + SY S + CD EG + L G L CT ++G W+
Sbjct: 514 LSPQNGTMTCVQPLGSSSYKSTCQFICD----EG--YSLSGPERLDCT----RSGRWTDS 563
Query: 339 APRCELSTSAVQCPH---PQILRGRM-VSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCN 394
P CE A++CP P+ +G + S + + T F+C GF L+G + C
Sbjct: 564 PPMCE----AIKCPELFAPE--QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECT 617
Query: 395 AQGTWEPSAPVCEKECQAP-PNI----LNGQKEDRHMVRFDPG-----TSIKYSCNPGYV 444
G W + P C+ P P + L + R PG T+ + CN G+
Sbjct: 618 TSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFT 677
Query: 445 LVGEESIQCTSEGVWTPPVPQCKVAACEA--TGRQLLTKPQHQFVRPDVNSSCG----EG 498
L+G+ ++ C G WT P C+ C + + + + S C EG
Sbjct: 678 LIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEG 737
Query: 499 YKLSGSVYQECQGTIPWFMEIRLCK 523
L+GS CQ W + C+
Sbjct: 738 QLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 157 bits (397), Expect = 5e-38
Identities = 126/453 (27%), Positives = 177/453 (39%), Gaps = 56/453 (12%)
Query: 39 TPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSSCPEPIVPG 98
T A G+ ++ C +R+ G L CI G W P P CE SC EP+
Sbjct: 342 TAFAYGSSCKFECQPGYRVRGLDMLRCID----SGHWSAPLPTCEAI----SC-EPLESP 392
Query: 99 GYKIRGSTP----YRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVFPLEC 154
+ +P +++ + +F C F + G V C W P C + L+C
Sbjct: 393 VHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQW-TAPAPVCQA---LQC 448
Query: 155 PALPMIHNGH-HTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
LP+ + + S G+ +++C G LLVG ++ CL++G W++VPP C+
Sbjct: 449 QDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAI 508
Query: 214 RCKSLGRFPNGK---VKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMP 269
C L NG V+ T F CDEGY L GP C +G+ WT P
Sbjct: 509 PCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR---WTDSPP 565
Query: 270 VCEEIFCPSP-PPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVD 328
+CE I CP P ++ + GS ++CD F L G + + CT
Sbjct: 566 MCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDN------GFKLEGPNNVECTT- 618
Query: 329 SQKTGTWSGPAPRCE----LSTSAVQCPHPQILRGRMVSGQKDRYT--------YNDTVI 376
+G WS P C+ L T VQCP GQ Y +N T
Sbjct: 619 ---SGRWSATPPTCKGIASLPTPGVQCP------ALTTPGQGTMYCRHHPGTFGFNTTCY 669
Query: 377 FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE--KECQAPPNILNGQKEDRHMVRFDPGTS 434
F C GFTL G + C G W P C K + N F G+
Sbjct: 670 FGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSI 729
Query: 435 IKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
+ C G +L G C G W+ VP C+
Sbjct: 730 CSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 132 bits (331), Expect = 2e-30
Identities = 92/355 (25%), Positives = 154/355 (43%), Gaps = 33/355 (9%)
Query: 697 VGNKSIHCMPSGNWSPSAPRCE--------ETCQHVRQSLQELPAG--SRVELVNTSCQD 746
+GN + C P P CE E QHV + P G S + C D
Sbjct: 178 IGNYTCSCYPGFY----GPECEYVRECGELELPQHVLMNCSH-PLGNFSFNSQCSFHCTD 232
Query: 747 GYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGM-MAENFLYGNEVSY 805
GYQ+ G + C +GIW K P C C P + G T + A+ F + + S+
Sbjct: 233 GYQVNGPSKLEC--LASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSF 290
Query: 806 ECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTH--S 863
C++GF L+G + +QC + G W+ P+P C +C + E ++ H +
Sbjct: 291 SCEEGFALVGPEVVQCTAS----GVWTAPAPVC----KAVQCQHLEAPSEGTMDCVHPLT 342
Query: 864 AYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGN-HT 922
A+++ +C PG+ + G ++RC W +PTC I C P +G+
Sbjct: 343 AFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTC---EAISCEPLESPVHGSMDC 399
Query: 923 GGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSS-PADMDGIQ 981
++ F + + C +G++L G ++ C + G W+ PAP C+ + C P +
Sbjct: 400 SPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARV 459
Query: 982 KGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVL 1036
P ++Y +V + C +G +L G+ QC + WN C++ P+L
Sbjct: 460 NCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLL 514
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 165 bits (417), Expect = 2e-40
Identities = 152/571 (26%), Positives = 247/571 (43%), Gaps = 79/571 (13%)
Query: 23 CGSPPPILNGRIS-YYST------PIAVGTVIRYSCSGTFRLIG---EKSLLCITKDKVD 72
CG P + NGRI+ YY T P+++ + + C + E+ C T+
Sbjct: 25 CGFPH-VENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEG--- 80
Query: 73 GTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKS--- 129
W P P+C + C +P + GY Y+ +++ + C + + G K
Sbjct: 81 --WS-PEPRC-----FKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEV 132
Query: 130 VWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHH-TSENVGSIAPGLSVTYSCESGYL 188
V C ++ G + PTC E P ++NG++ T++ + V Y C +GY
Sbjct: 133 VQCLSD---GWSSQPTCRKEH--ETCLAPELYNGNYSTTQKTFKVKD--KVQYECATGYY 185
Query: 189 LVGEKI---INCLSSGKWSAVPPTCEEARCKSLGRFPNG---KVKEPPILRVGVTANFFC 242
G K + CL+ G WS + P C + +C SL NG VK+ G FFC
Sbjct: 186 TAGGKKTEEVECLTYG-WS-LTPKCTKLKCSSLRLIENGYFHPVKQT--YEEGDVVQFFC 241
Query: 243 DEGYRLQGPPSSRCVIAGQGVAWTKMPVCE--EIFCPSPPPILNGRHIGNSLANVSYGSI 300
E Y L G +C G + + PVCE CP PP +N + I +G I
Sbjct: 242 HENYYLSGSDLIQCYNFGW---YPESPVCEGRRNRCPPPPLPINSK-IQTHSTTYRHGEI 297
Query: 301 VTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGR 360
V C+ +NF + G + +RC + G W+ P P+C V C P +
Sbjct: 298 VHIECE------LNFEIHGSAEIRC-----EDGKWTEP-PKCIEGQEKVACEEPPFIENG 345
Query: 361 MVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWE--PSAPVCEKECQAPPNILN 418
+ Y D V +AC G+ L GS +I CN +G W P + C+ PP ++N
Sbjct: 346 AANLHSKIYYNGDKVTYACKSGYLLHGSNEITCN-RGKWTLPPECVENNENCKHPPVVMN 404
Query: 419 GQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC------KVAACE 472
G D + + G+S++Y CN Y+L G + +C +G W+ P P C V
Sbjct: 405 GAVADGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWSSP-PVCLEPCTVNVDYMN 462
Query: 473 ATGRQLLTKPQHQFVRPD-VNSSCGEGYKLS-----GSVYQEC-QGTIPWFMEIRLCKEI 525
++ K + + + D ++ C +GY LS + +C +G + + + R +
Sbjct: 463 RNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKG 522
Query: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTC 556
C PP+I +G S+++ + G++V Y C
Sbjct: 523 MCTSPPLIKHGVIISSTVDTYENGSSVEYRC 553
Score = 128 bits (322), Expect = 3e-29
Identities = 124/457 (27%), Positives = 185/457 (40%), Gaps = 62/457 (13%)
Query: 602 CSHVHIANG------YKISGKEAPYFYNDTVTFKCYSGFTLKGS---SQIRCKADNTWDP 652
C H+ NG Y P + ++F C +G+T + Q C + W P
Sbjct: 25 CGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEG-WSP 83
Query: 653 EIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKS---IHCMPSGN 709
E P C K C + P L +G + ++ + + Y C GY G K + C+ G
Sbjct: 84 E-PRCFKKC-TKPDLSNGYISDVKLLYKIQE-NMRYGCASGYKTTGGKDEEVVQCLSDG- 139
Query: 710 WSPSAPRCEETCQHVRQSLQELPAGSRV---------ELVNTSCQDGYQLTGHAYQMCQD 760
WS S P C + +H EL G+ + V C GY G +
Sbjct: 140 WS-SQPTCRK--EHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVE 196
Query: 761 AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ 820
W P C + C +I NG + + + + G+ V + C + +YL G +Q
Sbjct: 197 CLTYGW-SLTPKCTKLKCSSLRLIENG-YFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQ 254
Query: 821 CRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFI 880
C + W SP C RCP P + K+ + Y H +IV+++C F
Sbjct: 255 CYNFG-----WYPESPVC--EGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFE 307
Query: 881 MNGSRVIRCHTDNTWVPGVPTCIK-KAFIGCPPPPKTPNGNHTGGNIAR--FSPGMSILY 937
++GS IRC D W P CI+ + + C PP NG N+ + G + Y
Sbjct: 308 IHGSAEIRCE-DGKWTE-PPKCIEGQEKVACEEPPFIENG---AANLHSKIYYNGDKVTY 362
Query: 938 SCDQGYLLVGEALLLCTHEGTWSQPAPHCKE--VNCSSP------ADMDGIQKGLEPRKM 989
+C GYLL G + C + G W+ P P C E NC P A DGI
Sbjct: 363 ACKSGYLLHGSNEITC-NRGKWTLP-PECVENNENCKHPPVVMNGAVADGILAS------ 414
Query: 990 YQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAV 1026
Y G+ V C + Y+L GS S+C+ +PP+ +
Sbjct: 415 YATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCL 451
Score = 126 bits (316), Expect = 1e-28
Identities = 143/572 (25%), Positives = 222/572 (38%), Gaps = 73/572 (12%)
Query: 179 VTYSCESGYLLVG---EKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPIL-RV 234
+++ C +GY E+ C + G WS P ++ L NG + + +L ++
Sbjct: 55 LSFFCLAGYTTESGRQEEQTTCTTEG-WSPEPRCFKKCTKPDLS---NGYISDVKLLYKI 110
Query: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
+ C GY+ G V+ W+ P C + P L + +
Sbjct: 111 QENMRYGCASGYKTTGGKDEE-VVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKT 169
Query: 295 VSYGSIVTYTCDPDPEEGVNFILIGEST--LRCTVDSQKTGTWSGPAPRCELSTSAVQCP 352
V Y C + G+ T + C T WS P+C + ++C
Sbjct: 170 FKVKDKVQYECATG-----YYTAGGKKTEEVECL-----TYGWS-LTPKC----TKLKCS 214
Query: 353 HPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE---KE 409
+++ K Y D V F C + L GS I+C G W P +PVCE
Sbjct: 215 SLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNR 273
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC--- 466
C PP +N K H + G + C + + G I+C +G WT P P+C
Sbjct: 274 CPPPPLPINS-KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWTEP-PKCIEG 330
Query: 467 --KVAACEATGRQLLTKPQHQFVRPD---VNSSCGEGYKLSGSVYQECQGTIPWFMEIRL 521
KVA E + H + + V +C GY L GS C W +
Sbjct: 331 QEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG-KWTLPPEC 389
Query: 522 CKEI-TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSND 580
+ C PPV+ NGA L + G++V Y CN + L G RC
Sbjct: 390 VENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNE------YYLLRGSKISRC---- 439
Query: 581 QERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK-EAPYFYNDTVTFKCYSGFTLK-- 637
E+G WS P P+C L V +++ N ++ K E + D + F C G+ L
Sbjct: 440 -EQGKWSSP-PVC-LEPCTVNVDYMN-RNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPL 495
Query: 638 ---GSSQIRCKADNTWDPEIPVC----EKG-CQSPPGLHHGRHTGGNTVFFVSGMTVDYT 689
++C N + + P+C KG C SPP + HG + +G +V+Y
Sbjct: 496 TPLSELSVQC---NRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYR 552
Query: 690 CDPGYLLVGNKSIHCMPSGNWSPSAPRCEETC 721
C + L G++ +C+ G W+ + P C E C
Sbjct: 553 CFDHHFLEGSREAYCL-DGMWT-TPPLCLEPC 582
Score = 102 bits (255), Expect = 2e-21
Identities = 135/549 (24%), Positives = 214/549 (38%), Gaps = 87/549 (15%)
Query: 515 WFMEIRLCKEITCPPPPVIYNGAHTGSSL-----EDFPYGTTVTYTCNPGPERGVEFSLI 569
W E R K+ T P + NG + L E+ YG Y G +
Sbjct: 81 WSPEPRCFKKCTKPD---LSNGYISDVKLLYKIQENMRYGCASGYKTTGGKD-------- 129
Query: 570 GESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFK 629
E ++C S+ WS P C+ C + NG S + + D V ++
Sbjct: 130 -EEVVQCLSDG-----WSSQ-PTCRKE--HETCLAPELYNG-NYSTTQKTFKVKDKVQYE 179
Query: 630 CYSGFTLKGSSQIRCKADNTWDPEI-PVCEK-GCQSPPGLHHGR-HTGGNTVFFVSGMTV 686
C +G+ G + T+ + P C K C S + +G H T + G V
Sbjct: 180 CATGYYTAGGKKTEEVECLTYGWSLTPKCTKLKCSSLRLIENGYFHPVKQT--YEEGDVV 237
Query: 687 DYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQHVRQSLQELPAGSRV--------- 737
+ C Y L G+ I C G W P +P CE + R LP S++
Sbjct: 238 QFFCHENYYLSGSDLIQCYNFG-WYPESPVCEG--RRNRCPPPPLPINSKIQTHSTTYRH 294
Query: 738 -ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC----KVIHCHPPPVIVNGKHTGM 792
E+V+ C+ +++ G A C+D G W + P C + + C PP I NG +
Sbjct: 295 GEIVHIECELNFEIHGSAEIRCED---GKWTEP-PKCIEGQEKVACEEPPFIENGA-ANL 349
Query: 793 MAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV 852
++ + G++V+Y C G+ L G ++ C G W+ P P+C+ + + P P V
Sbjct: 350 HSKIYYNGDKVTYACKSGYLLHGSNEITCN-----RGKWTLP-PECVENNENCKHP-PVV 402
Query: 853 KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPP 912
+G + ++Y+ V CN +++ GS++ RC P P C++
Sbjct: 403 MNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP--PVCLE-------- 452
Query: 913 PPKTPNGNHTGGNIARFS--------PGMSILYSCDQGYLL-----VGEALLLCTHEGTW 959
P T N ++ N G I + C QGY L + E + C + G
Sbjct: 453 -PCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQC-NRGEV 510
Query: 960 SQPAPHCKEVN--CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSD 1017
P KE C+SP + Y+ G+ V C D + LEGS ++ C
Sbjct: 511 KYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDG 570
Query: 1018 HQWNPPLAV 1026
PPL +
Sbjct: 571 MWTTPPLCL 579
Score = 57.8 bits (138), Expect = 6e-08
Identities = 58/271 (21%), Positives = 98/271 (36%), Gaps = 42/271 (15%)
Query: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
++C PP I NG + +S G + Y+C + L G + C G W P P
Sbjct: 334 VACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR-----GKWTLP-P 387
Query: 81 KCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
+C N+ P ++ G Y G SV + C + + G+K C+ P
Sbjct: 388 ECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP 447
Query: 141 TRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLL-----VGEKII 195
P C+ + + +N + G + G + + C+ GY L + E +
Sbjct: 448 ---PVCLEPCTVNVDYMNR-NNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSV 503
Query: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV-------------TANFFC 242
C + P C K G PP+++ GV + + C
Sbjct: 504 QC---NRGEVKYPLCTRKESK-------GMCTSPPLIKHGVIISSTVDTYENGSSVEYRC 553
Query: 243 DEGYRLQGPPSSRCVIAGQGVAWTKMPVCEE 273
+ + L+G + C+ WT P+C E
Sbjct: 554 FDHHFLEGSREAYCLDG----MWTTPPLCLE 580
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 159 bits (401), Expect = 2e-38
Identities = 129/453 (28%), Positives = 196/453 (43%), Gaps = 48/453 (10%)
Query: 115 TFACKTNFSMNGN-------KSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTS 167
T AC TN S +G+ + C+ + + + V+ LE P H S
Sbjct: 140 TAAC-TNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPE----HGSLVCS 194
Query: 168 ENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKV- 226
+G+ + S + SC+ GYL + + C+SSG+WSA P C C ++ NG V
Sbjct: 195 HPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVE 254
Query: 227 --KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPIL 283
+ P T F C+EG+ L G S +C +G W + P C+ + C +
Sbjct: 255 CFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN---WDNEKPTCKAVTCRAVRQPQ 311
Query: 284 NG--RHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPR 341
NG R + ++ S +TC EEG F+L G + + CT G W+ P
Sbjct: 312 NGSVRCSHSPAGEFTFKSSCNFTC----EEG--FMLQGPAQVECTTQ----GQWTQQIPV 361
Query: 342 CELSTSAVQC---PHPQILRGRM--VSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQ 396
CE A QC +P+ RG M + + Y + F+C GF LKGSK+++C
Sbjct: 362 CE----AFQCTALSNPE--RGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPT 415
Query: 397 GTWEPSAPVCEK-ECQAPPNILNGQKEDRH--MVRFDPGTSIKYSCNPGYVLVGEESIQC 453
G W+ P CE C A G H + F +S +SC G+ L G ++C
Sbjct: 416 GEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLEC 475
Query: 454 TSEGVWTPPVPQCKVAACEA---TGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ 510
TS+G WT VP C+V C + G+ ++ +C EG+ L+GS + C
Sbjct: 476 TSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCG 535
Query: 511 GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSL 543
T W + C+ T P++ + G SL
Sbjct: 536 ATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSL 568
Score = 149 bits (375), Expect = 2e-35
Identities = 122/442 (27%), Positives = 183/442 (41%), Gaps = 54/442 (12%)
Query: 627 TFKCYSGFT-LKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMT 685
T KC GF+ LK + C A + + VC H GN F +
Sbjct: 162 TCKCDPGFSGLKCEQIVNCTALESPEHGSLVCS-------------HPLGN---FSYNSS 205
Query: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQSLQELPAGSRVELV---- 740
+CD GYL +++ CM SG WS P C C V PA VE
Sbjct: 206 CSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTN-----PANGFVECFQNPG 260
Query: 741 ----NTSC----QDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNG--KHT 790
NT+C ++G++L G Q Q +G W + P CK + C NG + +
Sbjct: 261 SFPWNTTCTFDCEEGFELMGA--QSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCS 318
Query: 791 GMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP 850
A F + + ++ C++GF L G +++C + G W+ P C + T NP
Sbjct: 319 HSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQ----GQWTQQIPVC-EAFQCTALSNP 373
Query: 851 EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 910
E + L ++ + C GF++ GS+ ++C W PTC + C
Sbjct: 374 ERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC---EAVRC 430
Query: 911 PPPPKTPNG--NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKE 968
+ P G I F+ S +SC++G+ L G L CT +G W++ P C+
Sbjct: 431 DAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQV 490
Query: 969 VNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 1028
V CSS A I + +G V C +G+ L GS C + W+ L C
Sbjct: 491 VKCSSLAVPGKINMSCSGEPV--FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Query: 1029 --SRSLAPVLCGI-AAGLILLT 1047
+ S P++ G+ AAGL LLT
Sbjct: 549 APTESNIPLVAGLSAAGLSLLT 570
Score = 139 bits (351), Expect = 1e-32
Identities = 104/376 (27%), Positives = 163/376 (43%), Gaps = 57/376 (15%)
Query: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR 488
F +S SC+ GY+ E++QC S G W+ P+P C V C+A +T P + FV
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDA-----VTNPANGFVE 254
Query: 489 PDVNS-----------SCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGA 537
N C EG++L G+ +C + W E CK +TC NG+
Sbjct: 255 CFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGS 314
Query: 538 --HTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKL 595
+ S +F + ++ +TC G F L G + + CT+ +G W+ P+C+
Sbjct: 315 VRCSHSPAGEFTFKSSCNFTCEEG------FMLQGPAQVECTT----QGQWTQQIPVCE- 363
Query: 596 SLLAVQCSHV-HIANGYK--ISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDP 652
A QC+ + + GY + + Y + F C GF LKGS +++C WD
Sbjct: 364 ---AFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN 420
Query: 653 EIPVCEK-GC----QSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPS 707
E P CE C Q P GL H+ + S ++C+ G+ L G+ + C
Sbjct: 421 EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCA--FSCEEGFELHGSTQLECTSQ 478
Query: 708 GNWSPSAPRCEETCQHVRQSLQELP-------AGSRV--ELVNTSCQDGYQLTGHAYQMC 758
G W+ P +CQ V+ S +P +G V + +C +G+ L G A + C
Sbjct: 479 GQWTEEVP----SCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTC 534
Query: 759 QDAENGIWFKKIPLCK 774
G W +P C+
Sbjct: 535 --GATGHWSGLLPTCE 548
Score = 115 bits (289), Expect = 2e-25
Identities = 95/343 (27%), Positives = 140/343 (40%), Gaps = 44/343 (12%)
Query: 21 ISCGSPPPILNGRISYYSTPIAV--GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKP 78
+ C + NG + + P + T + C F L+G +SL C + G WD
Sbjct: 240 VECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSS----GNWDNE 295
Query: 79 APKCEYFNKYSSCPEPIVPGGYKIRGSTP----YRHGDSVTFACKTNFSMNGNKSVWCQA 134
P C K +C P +R S + S F C+ F + G V C
Sbjct: 296 KPTC----KAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 351
Query: 135 NNMWGPTRLPTCVSVFPLECPALPMIHNGHHTS--ENVGSIAPGLSVTYSCESGYLLVGE 192
W ++P C + +C AL G+ GS G S +SCE G++L G
Sbjct: 352 QGQW-TQQIPVCEA---FQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGS 407
Query: 193 KIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVK--EPPI--LRVGVTANFFCDEGYRL 248
K + C +G+W PTCE RC ++ + P G V+ PI + F C+EG+ L
Sbjct: 408 KRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFEL 467
Query: 249 QGPPSSRCVIAGQGVAWT-KMPVCEEIFCPS--PPPILNGRHIGNSLANVSYGSIVTYTC 305
G C GQ WT ++P C+ + C S P +N G + +G++ + C
Sbjct: 468 HGSTQLECTSQGQ---WTEEVPSCQVVKCSSLAVPGKINMSCSGEPV----FGTVCKFAC 520
Query: 306 DPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSA 348
PE + L G + C TG WSG P CE T +
Sbjct: 521 ---PE---GWTLNGSAARTCGA----TGHWSGLLPTCEAPTES 553
>gi|27502413 CD46 antigen, complement regulatory protein isoform 7
precursor [Homo sapiens]
Length = 378
Score = 143 bits (360), Expect = 1e-33
Identities = 93/283 (32%), Positives = 130/283 (45%), Gaps = 25/283 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK----GCQSPPGLHHGRHTGGNT 677
S I C +++TWDP +P C K PP L H T T
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTT 307
Score = 134 bits (337), Expect = 5e-31
Identities = 86/269 (31%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPP 914
I C +++TW P VP C+K PP
Sbjct: 267 TIVCDSNSTWDPPVPKCLKVLPPSSTKPP 295
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 106 bits (265), Expect = 1e-22
Identities = 74/282 (26%), Positives = 121/282 (42%), Gaps = 32/282 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT 861
C S+S +W P P+CL+ P + P + H + T
Sbjct: 269 VCDSNS----TWDPPVPKCLKVLPPSSTKPPALSHSVSTSST 306
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 85.1 bits (209), Expect = 3e-16
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 19/179 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 969
P NG G +F ++++ CD+G+ L G ++C TW P P C +V
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 16/175 (9%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYL 188
+N+ W P +P C+ V P P + + TS S A S E G L
Sbjct: 272 SNSTWDPP-VPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGYPKPEEGIL 325
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
>gi|27502402 CD46 antigen, complement regulatory protein isoform 1
precursor [Homo sapiens]
Length = 392
Score = 143 bits (360), Expect = 1e-33
Identities = 93/283 (32%), Positives = 130/283 (45%), Gaps = 25/283 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK----GCQSPPGLHHGRHTGGNT 677
S I C +++TWDP +P C K PP L H T T
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTT 307
Score = 134 bits (337), Expect = 5e-31
Identities = 86/269 (31%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPP 914
I C +++TW P VP C+K PP
Sbjct: 267 TIVCDSNSTWDPPVPKCLKVLPPSSTKPP 295
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 106 bits (265), Expect = 1e-22
Identities = 74/282 (26%), Positives = 121/282 (42%), Gaps = 32/282 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT 861
C S+S +W P P+CL+ P + P + H + T
Sbjct: 269 VCDSNS----TWDPPVPKCLKVLPPSSTKPPALSHSVSTSST 306
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 85.1 bits (209), Expect = 3e-16
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 19/179 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 969
P NG G +F ++++ CD+G+ L G ++C TW P P C +V
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 67.0 bits (162), Expect = 9e-11
Identities = 48/171 (28%), Positives = 78/171 (45%), Gaps = 19/171 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFP---LECPALPMIHNGHHTSENVGSIAPGLSVTY 181
+N+ W P +P C+ V P + PAL + T+++ S A G TY
Sbjct: 272 SNSTWDPP-VPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTY 321
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
>gi|27502425 CD46 antigen, complement regulatory protein isoform 8
precursor [Homo sapiens]
Length = 385
Score = 143 bits (360), Expect = 1e-33
Identities = 93/283 (32%), Positives = 130/283 (45%), Gaps = 25/283 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK----GCQSPPGLHHGRHTGGNT 677
S I C +++TWDP +P C K PP L H T T
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTT 307
Score = 134 bits (337), Expect = 5e-31
Identities = 86/269 (31%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPP 914
I C +++TW P VP C+K PP
Sbjct: 267 TIVCDSNSTWDPPVPKCLKVLPPSSTKPP 295
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 106 bits (265), Expect = 1e-22
Identities = 74/282 (26%), Positives = 121/282 (42%), Gaps = 32/282 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT 861
C S+S +W P P+CL+ P + P + H + T
Sbjct: 269 VCDSNS----TWDPPVPKCLKVLPPSSTKPPALSHSVSTSST 306
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 85.1 bits (209), Expect = 3e-16
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 19/179 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 969
P NG G +F ++++ CD+G+ L G ++C TW P P C +V
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/175 (27%), Positives = 75/175 (42%), Gaps = 16/175 (9%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYL 188
+N+ W P +P C+ V P P + + TS S A S E G L
Sbjct: 272 SNSTWDPP-VPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGYPKPEEGIL 325
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
>gi|27502423 CD46 antigen, complement regulatory protein isoform 2
precursor [Homo sapiens]
Length = 399
Score = 143 bits (360), Expect = 1e-33
Identities = 93/283 (32%), Positives = 130/283 (45%), Gaps = 25/283 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK----GCQSPPGLHHGRHTGGNT 677
S I C +++TWDP +P C K PP L H T T
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTT 307
Score = 134 bits (337), Expect = 5e-31
Identities = 86/269 (31%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPP 914
I C +++TW P VP C+K PP
Sbjct: 267 TIVCDSNSTWDPPVPKCLKVLPPSSTKPP 295
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 106 bits (265), Expect = 1e-22
Identities = 74/282 (26%), Positives = 121/282 (42%), Gaps = 32/282 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKT 861
C S+S +W P P+CL+ P + P + H + T
Sbjct: 269 VCDSNS----TWDPPVPKCLKVLPPSSTKPPALSHSVSTSST 306
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 85.1 bits (209), Expect = 3e-16
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 19/179 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 969
P NG G +F ++++ CD+G+ L G ++C TW P P C +V
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 67.0 bits (162), Expect = 9e-11
Identities = 48/171 (28%), Positives = 78/171 (45%), Gaps = 19/171 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFP---LECPALPMIHNGHHTSENVGSIAPGLSVTY 181
+N+ W P +P C+ V P + PAL + T+++ S A G TY
Sbjct: 272 SNSTWDPP-VPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTY 321
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
>gi|27502419 CD46 antigen, complement regulatory protein isoform 11
precursor [Homo sapiens]
Length = 348
Score = 141 bits (356), Expect = 3e-33
Identities = 89/266 (33%), Positives = 126/266 (47%), Gaps = 21/266 (7%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEKGCQSP 664
S I C +++TWDP +P C KG P
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKGYPKP 290
Score = 134 bits (338), Expect = 4e-31
Identities = 87/268 (32%), Positives = 126/268 (47%), Gaps = 27/268 (10%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPP 913
I C +++TW P VP C+K G P P
Sbjct: 267 TIVCDSNSTWDPPVPKCLK----GYPKP 290
Score = 132 bits (333), Expect = 1e-30
Identities = 81/243 (33%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY 287
Query: 411 QAP 413
P
Sbjct: 288 PKP 290
Score = 112 bits (281), Expect = 1e-24
Identities = 81/317 (25%), Positives = 125/317 (39%), Gaps = 30/317 (9%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVCRSRSLAP-----------VLCGIAAGLILLTFLIVITLYVIS 1058
C S+ W+PP+ C P V+ I +++ +I + Y
Sbjct: 266 DTIVCDSNSTWDPPVPKCLKGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYL 325
Query: 1059 KHRAR--NYYTDTSQKE 1073
+ R + Y TD + +E
Sbjct: 326 QRRKKKGTYLTDETHRE 342
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
Score = 61.6 bits (148), Expect = 4e-09
Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 16/138 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFP 151
+N+ W P +P C+ +P
Sbjct: 272 SNSTWDPP-VPKCLKGYP 288
>gi|27502427 CD46 antigen, complement regulatory protein isoform 12
precursor [Homo sapiens]
Length = 355
Score = 141 bits (356), Expect = 3e-33
Identities = 89/266 (33%), Positives = 126/266 (47%), Gaps = 21/266 (7%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEKGCQSP 664
S I C +++TWDP +P C KG P
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKGYPKP 290
Score = 134 bits (338), Expect = 4e-31
Identities = 87/268 (32%), Positives = 126/268 (47%), Gaps = 27/268 (10%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPP 913
I C +++TW P VP C+K G P P
Sbjct: 267 TIVCDSNSTWDPPVPKCLK----GYPKP 290
Score = 132 bits (333), Expect = 1e-30
Identities = 81/243 (33%), Positives = 115/243 (47%), Gaps = 14/243 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKEC 410
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY 287
Query: 411 QAP 413
P
Sbjct: 288 PKP 290
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 84.3 bits (207), Expect = 6e-16
Identities = 54/195 (27%), Positives = 88/195 (45%), Gaps = 22/195 (11%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK-- 285
Query: 971 CSSPADMDGIQKGLE 985
P +GI L+
Sbjct: 286 -GYPKPEEGILDSLD 299
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
Score = 61.6 bits (148), Expect = 4e-09
Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 16/138 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCVSVFP 151
+N+ W P +P C+ +P
Sbjct: 272 SNSTWDPP-VPKCLKGYP 288
>gi|27502411 CD46 antigen, complement regulatory protein isoform 6
precursor [Homo sapiens]
Length = 369
Score = 140 bits (352), Expect = 9e-33
Identities = 88/262 (33%), Positives = 125/262 (47%), Gaps = 21/262 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEKG 660
S I C +++TWDP +P C KG
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKG 286
Score = 137 bits (346), Expect = 4e-32
Identities = 90/278 (32%), Positives = 130/278 (46%), Gaps = 27/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K G P K P N+ G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK----GPRPTYKPPVSNYPG 300
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 105 bits (262), Expect = 2e-22
Identities = 75/277 (27%), Positives = 119/277 (42%), Gaps = 32/277 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
C S+S +W P P+CL+ P T P GY
Sbjct: 269 VCDSNS----TWDPPVPKCLKGPRPTYKPPVSNYPGY 301
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCV 147
+N+ W P +P C+
Sbjct: 272 SNSTWDPP-VPKCL 284
>gi|27502409 CD46 antigen, complement regulatory protein isoform 5
precursor [Homo sapiens]
Length = 362
Score = 140 bits (352), Expect = 9e-33
Identities = 88/262 (33%), Positives = 125/262 (47%), Gaps = 21/262 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEKG 660
S I C +++TWDP +P C KG
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKG 286
Score = 137 bits (346), Expect = 4e-32
Identities = 90/278 (32%), Positives = 130/278 (46%), Gaps = 27/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K G P K P N+ G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK----GPRPTYKPPVSNYPG 300
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 105 bits (262), Expect = 2e-22
Identities = 75/277 (27%), Positives = 119/277 (42%), Gaps = 32/277 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
C S+S +W P P+CL+ P T P GY
Sbjct: 269 VCDSNS----TWDPPVPKCLKGPRPTYKPPVSNYPGY 301
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCV 147
+N+ W P +P C+
Sbjct: 272 SNSTWDPP-VPKCL 284
>gi|27502405 CD46 antigen, complement regulatory protein isoform 14
precursor [Homo sapiens]
Length = 349
Score = 140 bits (352), Expect = 9e-33
Identities = 88/262 (33%), Positives = 125/262 (47%), Gaps = 21/262 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEKG 660
S I C +++TWDP +P C KG
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLKG 286
Score = 137 bits (346), Expect = 4e-32
Identities = 90/278 (32%), Positives = 130/278 (46%), Gaps = 27/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K G P K P N+ G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK----GPRPTYKPPVSNYPG 300
Score = 132 bits (332), Expect = 2e-30
Identities = 80/238 (33%), Positives = 114/238 (47%), Gaps = 14/238 (5%)
Query: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPT---CEEARCKSLGRFPNGK-VKEPPI 231
G V Y C+ GY + + + + +P + C C + NG+ V
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGRHIGN 290
G +F C+EGY L G C + G W+ K P+CE++ C PP I NG+H +
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 291 SLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQ 350
+ Y VTY+CDP P F LIGEST+ C +S WS AP C++ V+
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAPECKV----VK 227
Query: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK 408
C P + G+ +SG ++ Y TV+F C GF L GS I C++ TW+P P C K
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK 285
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 105 bits (262), Expect = 2e-22
Identities = 75/277 (27%), Positives = 119/277 (42%), Gaps = 32/277 (11%)
Query: 602 CSHVHIANGYKISGKEAPYF-YNDTVTFKCYSGFTLKG--SSQIRCKADNTWDPEIPVCE 658
C ++ GK PY+ + V +KC G+ ++ C ++TW +PV +
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTW---LPVSD 91
Query: 659 KGCQSPPGLHHGRHTGGNTV----FFVSGMTVDYTCDPGYLLVGNKSIHCMPSGN---WS 711
C + G V + G + + C+ GY L+G + ++C G+ WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 712 PSAPRCEETC-------QHVRQSLQELPAGSRVELVNTSCQ-----DGYQLTGHAYQMCQ 759
P CE+ ++ + + E+ ++ V SC D + L G + C
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG 211
Query: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
D N +W + P CKV+ C P V+ NGK + F Y V +ECD+GFYL G +
Sbjct: 212 D--NSVWSRAAPECKVVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTI 268
Query: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
C S+S +W P P+CL+ P T P GY
Sbjct: 269 VCDSNS----TWDPPVPKCLKGPRPTYKPPVSNYPGY 301
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQC 466
W PPVP+C
Sbjct: 276 WDPPVPKC 283
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 33/268 (12%)
Query: 90 SCPEPIVPGGYKIRGSTP--YRHGDSVTFACKTNFSMNGNKSVW--CQANNMWGPTRLPT 145
+C EP ++ G Y G+ V + CK + + C N+ W P
Sbjct: 34 ACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDA 93
Query: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--- 202
C + CP + NG N G+ G + + C GY L+GE+I+ C G
Sbjct: 94 C---YRETCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 203 WSAVPPTCEEARCKSLGRFPNGK--VKEPPILRVGVTANFFCD-----EGYRLQGPPSSR 255
WS PP CE+ C + NGK E + + CD + + L G +
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIY 209
Query: 256 CVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
C G W++ P C+ + C P + NG+ I Y + V + CD
Sbjct: 210 C---GDNSVWSRAAPECKVVKCRF-PVVENGKQISGFGKKFYYKATVMFECDK------G 259
Query: 315 FILIGESTLRCTVDSQKTGTWSGPAPRC 342
F L G T+ C +S TW P P+C
Sbjct: 260 FYLDGSDTIVCDSNS----TWDPPVPKC 283
Score = 63.5 bits (153), Expect = 1e-09
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 15/187 (8%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFAC-----KTNFSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWS-RAA 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTC 210
P C
Sbjct: 277 DPPVPKC 283
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 21 ISCGSPPPILNGRISYYSTPI-AVGTVIRYSCSGT-----FRLIGEKSLLCITKDKVDGT 74
+ C PP I NG+ ++ + + YSC F LIGE ++ C +
Sbjct: 160 VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGD----NSV 215
Query: 75 WDKPAPKCEYFNKYSSCPEPIVPGGYKIRG-STPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
W + AP+C K C P+V G +I G + + +V F C F ++G+ ++ C
Sbjct: 216 WSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 134 ANNMWGPTRLPTCV 147
+N+ W P +P C+
Sbjct: 272 SNSTWDPP-VPKCL 284
>gi|27502421 CD46 antigen, complement regulatory protein isoform 13
precursor [Homo sapiens]
Length = 373
Score = 137 bits (346), Expect = 4e-32
Identities = 87/261 (33%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK 659
S I C +++TWDP +P C K
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLK 285
Score = 134 bits (337), Expect = 5e-31
Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 26/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K + K+P + +G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK---VSTSSTTKSPASSASG 301
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/256 (26%), Positives = 109/256 (42%), Gaps = 21/256 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQCKVAACEAT 474
W PPVP+C + +T
Sbjct: 276 WDPPVPKCLKVSTSST 291
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 19/183 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +V+
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Query: 971 CSS 973
SS
Sbjct: 288 TSS 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFACKTN-----FSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAA- 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEP 229
P C + S + P P
Sbjct: 277 DPPVPKCLKVSTSSTTKSPASSASGP 302
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 27 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 85
P + NG+ IS + + + C F L G +++C + + TWD P PKC
Sbjct: 231 PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDS----NSTWDPPVPKCLKV 286
Query: 86 NKYSSCPEP 94
+ S+ P
Sbjct: 287 STSSTTKSP 295
>gi|27502417 CD46 antigen, complement regulatory protein isoform 10
precursor [Homo sapiens]
Length = 370
Score = 137 bits (346), Expect = 4e-32
Identities = 87/261 (33%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK 659
S I C +++TWDP +P C K
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLK 285
Score = 134 bits (337), Expect = 5e-31
Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 26/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K + K+P + +G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK---VSTSSTTKSPASSASG 301
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/256 (26%), Positives = 109/256 (42%), Gaps = 21/256 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQCKVAACEAT 474
W PPVP+C + +T
Sbjct: 276 WDPPVPKCLKVSTSST 291
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 19/183 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +V+
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Query: 971 CSS 973
SS
Sbjct: 288 TSS 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 15/213 (7%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFACKTN-----FSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAA- 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV 236
P C + S + P P G+
Sbjct: 277 DPPVPKCLKVSTSSTTKSPASSASGYPKPEEGI 309
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 27 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 85
P + NG+ IS + + + C F L G +++C + + TWD P PKC
Sbjct: 231 PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDS----NSTWDPPVPKCLKV 286
Query: 86 NKYSSCPEP 94
+ S+ P
Sbjct: 287 STSSTTKSP 295
>gi|27502415 CD46 antigen, complement regulatory protein isoform 9
precursor [Homo sapiens]
Length = 363
Score = 137 bits (346), Expect = 4e-32
Identities = 87/261 (33%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK 659
S I C +++TWDP +P C K
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLK 285
Score = 134 bits (337), Expect = 5e-31
Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 26/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K + K+P + +G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK---VSTSSTTKSPASSASG 301
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/256 (26%), Positives = 109/256 (42%), Gaps = 21/256 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQCKVAACEAT 474
W PPVP+C + +T
Sbjct: 276 WDPPVPKCLKVSTSST 291
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 19/183 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +V+
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Query: 971 CSS 973
SS
Sbjct: 288 TSS 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 15/213 (7%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFACKTN-----FSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAA- 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV 236
P C + S + P P G+
Sbjct: 277 DPPVPKCLKVSTSSTTKSPASSASGYPKPEEGI 309
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 27 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 85
P + NG+ IS + + + C F L G +++C + + TWD P PKC
Sbjct: 231 PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDS----NSTWDPPVPKCLKV 286
Query: 86 NKYSSCPEP 94
+ S+ P
Sbjct: 287 STSSTTKSP 295
>gi|27502407 CD46 antigen, complement regulatory protein isoform 3
precursor [Homo sapiens]
Length = 377
Score = 137 bits (346), Expect = 4e-32
Identities = 87/261 (33%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK 659
S I C +++TWDP +P C K
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLK 285
Score = 134 bits (337), Expect = 5e-31
Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 26/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K + K+P + +G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK---VSTSSTTKSPASSASG 301
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/256 (26%), Positives = 109/256 (42%), Gaps = 21/256 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQCKVAACEAT 474
W PPVP+C + +T
Sbjct: 276 WDPPVPKCLKVSTSST 291
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 19/183 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +V+
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Query: 971 CSS 973
SS
Sbjct: 288 TSS 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFACKTN-----FSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAA- 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEP 229
P C + S + P P
Sbjct: 277 DPPVPKCLKVSTSSTTKSPASSASGP 302
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 27 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 85
P + NG+ IS + + + C F L G +++C + + TWD P PKC
Sbjct: 231 PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDS----NSTWDPPVPKCLKV 286
Query: 86 NKYSSCPEP 94
+ S+ P
Sbjct: 287 STSSTTKSP 295
>gi|24432108 CD46 antigen, complement regulatory protein isoform 4
precursor [Homo sapiens]
Length = 384
Score = 137 bits (346), Expect = 4e-32
Identities = 87/261 (33%), Positives = 124/261 (47%), Gaps = 21/261 (8%)
Query: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQ--CTSEGVWTPPVPQ-- 465
C+ PP + + ++ G + Y C GY + + C W P
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 466 ----CKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGS--VYQECQGTIP-WFME 518
C G+ + ++F ++ C EGY L G +Y E +G++ W +
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGY-QMHFICNEGYYLIGEEILYCELKGSVAIWSGK 153
Query: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
+C+++ C PPP I NG HT S +E F Y VTY+C+P P FSLIGESTI C
Sbjct: 154 PPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD 212
Query: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKG 638
N WS AP CK+ V+C + NG +ISG ++Y TV F+C GF L G
Sbjct: 213 NS----VWSRAAPECKV----VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDG 264
Query: 639 SSQIRCKADNTWDPEIPVCEK 659
S I C +++TWDP +P C K
Sbjct: 265 SDTIVCDSNSTWDPPVPKCLK 285
Score = 134 bits (337), Expect = 5e-31
Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 26/278 (9%)
Query: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH--CMPSGNWSP-SAPRC 717
C+ PP G ++ G VDY C GY + + H C + W P S C
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDAC 94
Query: 718 -EETCQHVRQSL--QELPAGSRVEL---VNTSCQDGYQLTGHAYQMCQ-DAENGIWFKKI 770
ETC ++R L Q +PA E ++ C +GY L G C+ IW K
Sbjct: 95 YRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKP 154
Query: 771 PLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG-----FYLLGEKKLQCRSDS 825
P+C+ + C PPP I NGKHT E F Y + V+Y CD F L+GE + C +S
Sbjct: 155 PICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNS 214
Query: 826 KGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSR 885
WS +P+C V +C P V++G +++ + + V +C+ GF ++GS
Sbjct: 215 ----VWSRAAPEC----KVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD 266
Query: 886 VIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTG 923
I C +++TW P VP C+K + K+P + +G
Sbjct: 267 TIVCDSNSTWDPPVPKCLK---VSTSSTTKSPASSASG 301
Score = 111 bits (277), Expect = 4e-24
Identities = 71/258 (27%), Positives = 105/258 (40%), Gaps = 17/258 (6%)
Query: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
C PP + G + G V Y+C +G++ + D + H
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICD-RNHTWLPVSDDA 93
Query: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT--- 894
C R CP + + Y ++ CN G+ + G ++ C +
Sbjct: 94 CYRET----CPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 895 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQG-----YLLVGEA 949
W P C K + C PPPK NG HT + F ++ YSCD + L+GE+
Sbjct: 150 WSGKPPICEK---VLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGES 206
Query: 950 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 1009
+ C WS+ AP CK V C P +G Q +K Y Y A V EC+ G+ L+GS
Sbjct: 207 TIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFY-YKATVMFECDKGFYLDGS 265
Query: 1010 PQSQCQSDHQWNPPLAVC 1027
C S+ W+PP+ C
Sbjct: 266 DTIVCDSNSTWDPPVPKC 283
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/256 (26%), Positives = 109/256 (42%), Gaps = 21/256 (8%)
Query: 227 KEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMP--VCEEIFCPSPPPILN 284
K P +G ++ C +GY PP + I + W + C CP LN
Sbjct: 49 KPKPYYEIGERVDYKCKKGY-FYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLN 107
Query: 285 GRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCEL 344
G+ + + +G + + C+ EG + LIGE L C + WSG P CE
Sbjct: 108 GQAVPAN-GTYEFGYQMHFICN----EG--YYLIGEEILYCELKGS-VAIWSGKPPICE- 158
Query: 345 STSAVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFG-----FTLKGSKQIRCNAQGT 398
V C P P+I G+ + + + Y D V ++C F+L G I C
Sbjct: 159 ---KVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 399 WEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGV 458
W +AP C+ P + NG++ +F ++ + C+ G+ L G ++I C S
Sbjct: 216 WSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNST 275
Query: 459 WTPPVPQCKVAACEAT 474
W PPVP+C + +T
Sbjct: 276 WDPPVPKCLKVSTSST 291
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 19/183 (10%)
Query: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGS-WSGPSPQCLRSPPVTRCPNPEVKHGYK 857
+G ++ + C++G+YL+GE+ L C + KG + WSG P C + V P P++K+G
Sbjct: 119 FGYQMHFICNEGYYLIGEEILYC--ELKGSVAIWSGKPPICEK---VLCTPPPKIKNGKH 173
Query: 858 LNKTHSAYSHNDIVYVDCNPG-----FIMNGSRVIRCHTDNTWVPGVPTC--IKKAFIGC 910
+ + D V C+P F + G I C ++ W P C +K F
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF--- 230
Query: 911 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVN 970
P NG G +F ++++ CD+G+ L G ++C TW P P C +V+
Sbjct: 231 ---PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Query: 971 CSS 973
SS
Sbjct: 288 TSS 290
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/206 (25%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 30 LNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYS 89
LNG+ + G + + C+ + LIGE+ L C K V W P CE K
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV-AIWSGKPPICE---KVL 161
Query: 90 SCPEPIVPGG-YKIRGSTPYRHGDSVTFACKTN-----FSMNGNKSVWCQANNMWGPTRL 143
P P + G + + + D+VT++C FS+ G +++C N++W
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAA- 220
Query: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
P C V +C P++ NG S +V + C+ G+ L G I C S+ W
Sbjct: 221 PECKVV---KC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 276
Query: 204 SAVPPTCEEARCKSLGRFPNGKVKEP 229
P C + S + P P
Sbjct: 277 DPPVPKCLKVSTSSTTKSPASSASGP 302
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 21/180 (11%)
Query: 613 ISGKEAP----YFYNDTVTFKCYSGFTLKGSSQIRCKADNT---WDPEIPVCEKG-CQSP 664
++G+ P Y + + F C G+ L G + C+ + W + P+CEK C P
Sbjct: 106 LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 165
Query: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPG-----YLLVGNKSIHCMPSGNWSPSAPRCEE 719
P + +G+HT F V Y+CDP + L+G +I+C + WS +AP C+
Sbjct: 166 PKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Query: 720 T-CQH--VRQSLQELPAGSRV---ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLC 773
C+ V Q G + V C G+ L G +C N W +P C
Sbjct: 226 VKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCD--SNSTWDPPVPKC 283
Score = 33.9 bits (76), Expect = 0.86
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 27 PPILNGR-ISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYF 85
P + NG+ IS + + + C F L G +++C + + TWD P PKC
Sbjct: 231 PVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDS----NSTWDPPVPKCLKV 286
Query: 86 NKYSSCPEP 94
+ S+ P
Sbjct: 287 STSSTTKSP 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,061,606
Number of Sequences: 37866
Number of extensions: 3118225
Number of successful extensions: 12591
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 6174
Number of HSP's gapped (non-prelim): 1871
length of query: 1092
length of database: 18,247,518
effective HSP length: 113
effective length of query: 979
effective length of database: 13,968,660
effective search space: 13675318140
effective search space used: 13675318140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.