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Search of human proteins with 53828924
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
(328 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53828924 G protein-coupled receptor 7 [Homo sapiens] 647 0.0
gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens] 392 e-109
gi|4557861 somatostatin receptor 3 [Homo sapiens] 241 6e-64
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 238 4e-63
gi|4557859 somatostatin receptor 2 [Homo sapiens] 228 6e-60
gi|4557857 somatostatin receptor 1 [Homo sapiens] 227 1e-59
gi|4505513 opiate receptor-like 1 [Homo sapiens] 225 4e-59
gi|33286424 opiate receptor-like 1 [Homo sapiens] 225 4e-59
gi|4557865 somatostatin receptor 5 [Homo sapiens] 220 2e-57
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 220 2e-57
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 220 2e-57
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 220 2e-57
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 220 2e-57
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 220 2e-57
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 220 2e-57
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 220 2e-57
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 220 2e-57
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 220 2e-57
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 220 2e-57
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 212 4e-55
gi|149944554 somatostatin receptor 4 [Homo sapiens] 209 2e-54
gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens] 192 4e-49
gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens] 190 1e-48
gi|223718087 opioid receptor, mu 1 isoform MOR1-K1 [Homo sapiens] 190 1e-48
gi|88758590 G protein-coupled receptor 24 [Homo sapiens] 158 5e-39
gi|7706103 relaxin/insulin-like family peptide receptor 3 [Homo ... 146 3e-35
gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 145 6e-35
gi|4503905 galanin receptor 2 [Homo sapiens] 144 1e-34
gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] 141 7e-34
gi|30581170 CC chemokine receptor 3 [Homo sapiens] 141 9e-34
>gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
Length = 328
Score = 647 bits (1669), Expect = 0.0
Identities = 328/328 (100%), Positives = 328/328 (100%)
Query: 1 MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY 60
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
Sbjct: 1 MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY 60
Query: 61 VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT 120
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
Sbjct: 61 VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT 120
Query: 121 FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD 180
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
Sbjct: 121 FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD 180
Query: 181 DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK 240
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
Sbjct: 181 DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK 240
Query: 241 ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS 300
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
Sbjct: 241 ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS 300
Query: 301 CLNPFLYAFLDASFRRNLRQLITCRAAA 328
CLNPFLYAFLDASFRRNLRQLITCRAAA
Sbjct: 301 CLNPFLYAFLDASFRRNLRQLITCRAAA 328
>gi|30581164 neuropeptides B/W receptor 2 [Homo sapiens]
Length = 333
Score = 392 bits (1006), Expect = e-109
Identities = 204/334 (61%), Positives = 250/334 (74%), Gaps = 11/334 (3%)
Query: 1 MDNASFSEPWPANASGPDPALSCS---------NASTLAPLPAPLAVAVPVVYAVICAVG 51
M A EP + S P + + NA+ PLP L V +P VY+ ICAVG
Sbjct: 1 MQAAGHPEPLDSRGSFSLPTMGANVSQDNGTGHNATFSEPLPF-LYVLLPAVYSGICAVG 59
Query: 52 LAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKL 111
L GN+AV+ V+LRAP+MKTVTN+FILNLA+AD LFTLVLP+NIA+ LL+ WPFGEL+CKL
Sbjct: 60 LTGNTAVILVILRAPKMKTVTNVFILNLAVADGLFTLVLPVNIAEHLLQYWPFGELLCKL 119
Query: 112 IVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVL 171
++A+D YN FSS+YFL VMS DRYLVVLAT SR + RTY A+ SL VW VT++VL
Sbjct: 120 VLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVL 179
Query: 172 PFAVFARL-DDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRL 230
PF FA + +E C L FP PE W++ASR+YTLVLGF +PV TICVLYT LL RL
Sbjct: 180 PFFSFAGVYSNELQVPSCGLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRL 239
Query: 231 HAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISY 290
A+RL S AKAL +A+++VT LV+ +LAVCLLCWTP+HL++VVALTTDLPQTPLVI++SY
Sbjct: 240 RAVRLRSGAKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISMSY 299
Query: 291 FITSLSYANSCLNPFLYAFLDASFRRNLRQLITC 324
ITSLSYANSCLNPFLYAFLD +FR+N R ++ C
Sbjct: 300 VITSLSYANSCLNPFLYAFLDDNFRKNFRSILRC 333
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 241 bits (615), Expect = 6e-64
Identities = 134/322 (41%), Positives = 196/322 (60%), Gaps = 12/322 (3%)
Query: 7 SEPWPANASGPDPALSCSNASTLAPLPAPLAVA---VPVVYAVICAVGLAGNSAVLYVLL 63
SEP A+++ P P + N S P PA LAV+ +P+VY V+C VGL GNS V+YV+L
Sbjct: 13 SEPENASSAWP-PDATLGNVSA-GPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVL 70
Query: 64 RAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSS 123
R +VTN++ILNLA+ADELF L LP A L WPFG LMC+L++A+D N F+S
Sbjct: 71 RHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTS 130
Query: 124 LYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQ 183
++ LTVMS DRYL V+ S R RT AR VS AVW +VVLP VF+ + +
Sbjct: 131 IFCLTVMSVDRYLAVVHPTRSAR--WRTAPVARTVSAAVWVASAVVVLPVVVFSGV--PR 186
Query: 184 GRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALE 243
G C + +P+P A W +YT LGF P+ IC+ Y ++ ++ + A + +
Sbjct: 187 GMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQ 246
Query: 244 ---RAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS 300
R+++RVT +VVA++A+ +LCW P+++ +V + LP+ P + + + +L YANS
Sbjct: 247 RRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANS 306
Query: 301 CLNPFLYAFLDASFRRNLRQLI 322
C NP LY FL F++ R+++
Sbjct: 307 CANPILYGFLSYRFKQGFRRVL 328
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 238 bits (608), Expect = 4e-63
Identities = 126/315 (40%), Positives = 194/315 (61%), Gaps = 13/315 (4%)
Query: 12 ANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTV 71
ANASGP A S AS+LA LA+A+ +Y+ +CAVGL GN V++ ++R +MKT
Sbjct: 32 ANASGPPGARS---ASSLA-----LAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTA 83
Query: 72 TNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMS 131
TN++I NLA+AD L T LP A +L+ WPFGEL+CK +++ID YN F+S++ LT+MS
Sbjct: 84 TNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMS 143
Query: 132 ADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLV 191
DRY+ V ++ + RT + A+ +++ +W + + V +P V A G C+L
Sbjct: 144 VDRYIAVCHPVKA--LDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQ 201
Query: 192 FPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTF 251
FP P +W +++ + F +P+ I V Y +L RL ++RL S +K +R+ +R+T
Sbjct: 202 FPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITR 261
Query: 252 LVVAILAVCLLCWTPYHLSTVVALTTDLP-QTPLVIAISYFITSLSYANSCLNPFLYAFL 310
+V+ ++ ++CW P H+ +V D+ + PLV+A + +L YANS LNP LYAFL
Sbjct: 262 MVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFL 321
Query: 311 DASFRRNLRQLITCR 325
D +F+R RQL CR
Sbjct: 322 DENFKRCFRQL--CR 334
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 228 bits (581), Expect = 6e-60
Identities = 106/281 (37%), Positives = 180/281 (64%), Gaps = 3/281 (1%)
Query: 43 VYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQW 102
+Y V+C +GL GN+ V+YV+LR +MKT+TN++ILNLAIADELF L LP L W
Sbjct: 49 IYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHW 108
Query: 103 PFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAV 162
PFG+ +C++++ +D N F+S++ LTVMS DRYL V+ +S + R A+ +++AV
Sbjct: 109 PFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAK--WRRPRTAKMITMAV 166
Query: 163 WGIVTLVVLPFAVFARLDDEQ-GRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICV 221
WG+ LV+LP ++A L Q GR C + +P W+ +YT +LGF +P++ IC+
Sbjct: 167 WGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICL 226
Query: 222 LYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQ 281
Y ++ ++ + + + ++++K+VT +V ++AV + CW P+++ V +++ +
Sbjct: 227 CYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISP 286
Query: 282 TPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLI 322
TP + + F+ L+YANSC NP LYAFL +F+++ + ++
Sbjct: 287 TPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVL 327
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 227 bits (579), Expect = 1e-59
Identities = 112/306 (36%), Positives = 187/306 (61%), Gaps = 8/306 (2%)
Query: 18 DPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFIL 77
+P + S TL+ A+ + +Y+V+C VGL GNS V+YV+LR +MKT TN++IL
Sbjct: 40 EPGRNASQNGTLSEGQGS-AILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYIL 98
Query: 78 NLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLV 137
NLAIADEL L +P + LLR WPFG L+C+L++++D N F+S+Y LTV+S DRY+
Sbjct: 99 NLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVA 158
Query: 138 VLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFAR-LDDEQGRRQCVLVFPQPE 196
V+ ++ R R + A+ V+L VW + LV+LP VF+R + G C ++ P+P
Sbjct: 159 VVHPIKAARY--RRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPA 216
Query: 197 AFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAI 256
W LYT ++GF +PV IC+ Y ++ ++ + L + + +R+++++T +V+ +
Sbjct: 217 QRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMV 276
Query: 257 LAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRR 316
+ V ++CW P+++ +V + + +S L YANSC NP LY FL +F+R
Sbjct: 277 VMVFVICWMPFYVVQLVNVFAEQDDA----TVSQLSVILGYANSCANPILYGFLSDNFKR 332
Query: 317 NLRQLI 322
+ ++++
Sbjct: 333 SFQRIL 338
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 225 bits (574), Expect = 4e-59
Identities = 120/304 (39%), Positives = 176/304 (57%), Gaps = 4/304 (1%)
Query: 25 NASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADE 84
NAS A LP L V + +Y +C GL GN V+YV+LR +MKT TN++I NLA+AD
Sbjct: 39 NASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADT 98
Query: 85 LFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAES 144
L L LP D LL WPFG +CK ++AID YN F+S + LT MS DRY+ + +
Sbjct: 99 LVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRA 158
Query: 145 RRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASR 204
V RT S A+AV++A+W + ++V +P A+ E +C++ P P+ +W
Sbjct: 159 LDV--RTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFA 216
Query: 205 LYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCW 264
+ + F +PV I V Y+ ++ RL +RL S ++ +R +R+T LV+ ++AV + CW
Sbjct: 217 ICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCW 276
Query: 265 TPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITC 324
TP + + P + +AI F T+L Y NSCLNP LYAFLD +F+ R+ C
Sbjct: 277 TPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKF--C 334
Query: 325 RAAA 328
A+A
Sbjct: 335 CASA 338
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 225 bits (574), Expect = 4e-59
Identities = 120/304 (39%), Positives = 176/304 (57%), Gaps = 4/304 (1%)
Query: 25 NASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADE 84
NAS A LP L V + +Y +C GL GN V+YV+LR +MKT TN++I NLA+AD
Sbjct: 39 NASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADT 98
Query: 85 LFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAES 144
L L LP D LL WPFG +CK ++AID YN F+S + LT MS DRY+ + +
Sbjct: 99 LVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRA 158
Query: 145 RRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASR 204
V RT S A+AV++A+W + ++V +P A+ E +C++ P P+ +W
Sbjct: 159 LDV--RTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFA 216
Query: 205 LYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCW 264
+ + F +PV I V Y+ ++ RL +RL S ++ +R +R+T LV+ ++AV + CW
Sbjct: 217 ICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCW 276
Query: 265 TPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITC 324
TP + + P + +AI F T+L Y NSCLNP LYAFLD +F+ R+ C
Sbjct: 277 TPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKF--C 334
Query: 325 RAAA 328
A+A
Sbjct: 335 CASA 338
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 220 bits (560), Expect = 2e-57
Identities = 123/316 (38%), Positives = 178/316 (56%), Gaps = 9/316 (2%)
Query: 13 NASGPDPALSCSNASTL---APLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMK 69
NAS P A + TL AP AV VPV+Y ++CA GL GN+ V+YV+LR +MK
Sbjct: 13 NASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMK 72
Query: 70 TVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTV 129
TVTN++ILNLA+AD L+ L LP WPFG ++C+L++ +D N F+S++ LTV
Sbjct: 73 TVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTV 132
Query: 130 MSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCV 189
MS DRYL V+ S R R A+ S A W + + LP VFA D Q C
Sbjct: 133 MSVDRYLAVVHPLSSAR--WRRPRVAKLASAAAWVLSLCMSLPLLVFA---DVQEGGTCN 187
Query: 190 LVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRV 249
+P+P W +YT VLGF P+ IC+ Y ++ ++ A + R++++V
Sbjct: 188 ASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGC-VRRRSERKV 246
Query: 250 TFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAF 309
T +V+ ++ V CW P+ +V L LPQ P + +F+ LSYANSC NP LY F
Sbjct: 247 TRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGF 306
Query: 310 LDASFRRNLRQLITCR 325
L +FR++ ++++ R
Sbjct: 307 LSDNFRQSFQKVLCLR 322
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 163 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 222
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 223 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 280
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 281 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 340
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 341 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 400
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 401 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 444
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 220 bits (560), Expect = 2e-57
Identities = 103/284 (36%), Positives = 169/284 (59%), Gaps = 2/284 (0%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A+ + +Y+++C VGL GN V+YV++R +MKT TN++I NLA+AD L T LP +
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN 129
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
+L+ WPFG ++CK++++ID YN F+S++ L MS DRY+ V ++ + RT A+
Sbjct: 130 YLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAK 187
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPV 216
+++ W + + + LP A QG C L F P +W ++ + F +PV
Sbjct: 188 IINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPV 247
Query: 217 STICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALT 276
I V Y ++ RL ++R+ S +K +R +R+T +V+ ++AV ++CWTP H+ ++
Sbjct: 248 LIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL 307
Query: 277 TDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQ 320
+P+T +F +L Y NSCLNP LYAFLD +F+R R+
Sbjct: 308 VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFRE 351
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 212 bits (539), Expect = 4e-55
Identities = 108/294 (36%), Positives = 178/294 (60%), Gaps = 9/294 (3%)
Query: 33 PAPLAVAVPV----VYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTL 88
PA ++ A+PV VY+V+ VGL GNS V++V++R +MKT TN++I NLA+AD L T
Sbjct: 51 PAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTT 110
Query: 89 VLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVA 148
+P +L+ WPFG+++CK++++ID YN F+S++ LT+MS DRY+ V ++ +
Sbjct: 111 TMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKA--LD 168
Query: 149 GRTYSAARAVSLAVWGIVTLVVLPFAVF--ARLDDEQGRRQCVLVFPQPEAFWWRA-SRL 205
RT A+ +++ +W + + V + V ++ ++ +C L FP + WW ++
Sbjct: 169 FRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKI 228
Query: 206 YTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWT 265
+ F IPV I V YT ++ RL ++RL S ++ +R +R+T LV+ ++AV ++CWT
Sbjct: 229 CVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWT 288
Query: 266 PYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLR 319
P H+ +V + ++ YF +L Y NS LNP LYAFLD +F+R R
Sbjct: 289 PIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFR 342
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 209 bits (533), Expect = 2e-54
Identities = 114/318 (35%), Positives = 182/318 (57%), Gaps = 9/318 (2%)
Query: 10 WPANASGPDPALSCSNASTLAPLPAPLA--VAVPVVYAVICAVGLAGNSAVLYVLLRAPR 67
WP+ A+ A P A A VA+ +YA++C VGL GN+ V++V+LR +
Sbjct: 19 WPSAANASSAPAEAEEA-VAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAK 77
Query: 68 MKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFL 127
MKT TN+++LNLA+ADELF L +P + LR WPFG ++C+ ++++D N F+S++ L
Sbjct: 78 MKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCL 137
Query: 128 TVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQ 187
TV+S DRY+ V+ R R S A+ ++L VW LV LP A+FA +G +
Sbjct: 138 TVLSVDRYVAVVHPL--RAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQA 195
Query: 188 CVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKK 247
P W +YT +LGF +PV I + Y ++ ++ A+ L + + R++K
Sbjct: 196 VACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEK 255
Query: 248 RVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLY 307
++T LV+ ++ V +LCW P+++ ++ L T L +++ LSYANSC NP LY
Sbjct: 256 KITRLVLMVVVVFVLCWMPFYVVQLLNLFV----TSLDATVNHVSLILSYANSCANPILY 311
Query: 308 AFLDASFRRNLRQLITCR 325
FL +FRR ++++ R
Sbjct: 312 GFLSDNFRRFFQRVLCLR 329
>gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens]
Length = 319
Score = 192 bits (487), Expect = 4e-49
Identities = 92/257 (35%), Positives = 149/257 (57%), Gaps = 2/257 (0%)
Query: 64 RAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSS 123
R +MKT TN++I NLA+AD L T LP ++L+ WPFG ++CK++++ID YN F+S
Sbjct: 16 RYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 75
Query: 124 LYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQ 183
++ L MS DRY+ V ++ + RT A+ +++ W + + + LP A Q
Sbjct: 76 IFTLCTMSVDRYIAVCHPVKA--LDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQ 133
Query: 184 GRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALE 243
G C L F P +W ++ + F +PV I V Y ++ RL ++R+ S +K +
Sbjct: 134 GSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKD 193
Query: 244 RAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLN 303
R +R+T +V+ ++AV ++CWTP H+ ++ +P+T +F +L Y NSCLN
Sbjct: 194 RNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLN 253
Query: 304 PFLYAFLDASFRRNLRQ 320
P LYAFLD +F+R R+
Sbjct: 254 PVLYAFLDENFKRCFRE 270
>gi|223718060 opioid receptor, mu 1 isoform MOR-1G1 [Homo sapiens]
Length = 300
Score = 190 bits (483), Expect = 1e-48
Identities = 91/253 (35%), Positives = 147/253 (58%), Gaps = 2/253 (0%)
Query: 68 MKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFL 127
MKT TN++I NLA+AD L T LP ++L+ WPFG ++CK++++ID YN F+S++ L
Sbjct: 1 MKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTL 60
Query: 128 TVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQ 187
MS DRY+ V ++ + RT A+ +++ W + + + LP A QG
Sbjct: 61 CTMSVDRYIAVCHPVKA--LDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSID 118
Query: 188 CVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKK 247
C L F P +W ++ + F +PV I V Y ++ RL ++R+ S +K +R +
Sbjct: 119 CTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLR 178
Query: 248 RVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLY 307
R+T +V+ ++AV ++CWTP H+ ++ +P+T +F +L Y NSCLNP LY
Sbjct: 179 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLY 238
Query: 308 AFLDASFRRNLRQ 320
AFLD +F+R R+
Sbjct: 239 AFLDENFKRCFRE 251
>gi|223718087 opioid receptor, mu 1 isoform MOR1-K1 [Homo sapiens]
Length = 300
Score = 190 bits (483), Expect = 1e-48
Identities = 91/253 (35%), Positives = 147/253 (58%), Gaps = 2/253 (0%)
Query: 68 MKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFL 127
MKT TN++I NLA+AD L T LP ++L+ WPFG ++CK++++ID YN F+S++ L
Sbjct: 1 MKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTL 60
Query: 128 TVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQ 187
MS DRY+ V ++ + RT A+ +++ W + + + LP A QG
Sbjct: 61 CTMSVDRYIAVCHPVKA--LDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSID 118
Query: 188 CVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKK 247
C L F P +W ++ + F +PV I V Y ++ RL ++R+ S +K +R +
Sbjct: 119 CTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLR 178
Query: 248 RVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLY 307
R+T +V+ ++AV ++CWTP H+ ++ +P+T +F +L Y NSCLNP LY
Sbjct: 179 RITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLY 238
Query: 308 AFLDASFRRNLRQ 320
AFLD +F+R R+
Sbjct: 239 AFLDENFKRCFRE 251
>gi|88758590 G protein-coupled receptor 24 [Homo sapiens]
Length = 422
Score = 158 bits (400), Expect = 5e-39
Identities = 106/329 (32%), Positives = 164/329 (49%), Gaps = 18/329 (5%)
Query: 1 MDNASFSEPWPANAS----GPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNS 56
MD + P NAS GPD S + + + + + +P V+ IC +G+ GNS
Sbjct: 70 MDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSI-SYINIIMPSVFGTICLLGIIGNS 128
Query: 57 AVLYVLLRAPRM---KTVTNLFILNLAIADELFTLVLPINIADFLLRQ-WPFGELMCKLI 112
V++ +++ ++ V ++FI+NL++ D LF L +P I + W FGE MC LI
Sbjct: 129 TVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLI 188
Query: 113 VAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLP 172
A+D + F+S Y LT M+ DRYL + S + R S A V +W + + + P
Sbjct: 189 TAMDANSQFTSTYILTAMAIDRYLATVHPISSTKF--RKPSVATLVICLLWALSFISITP 246
Query: 173 FAVFARLDDEQGRRQ-CVLVFPQPEA--FWWRASRLYTLVLGFAIPVSTICVLYTTLLCR 229
++ARL G C + P P+ +W+ LY L FA+P I Y +L R
Sbjct: 247 VWLYARLIPFPGGAVGCGIRLPNPDTDLYWFT---LYQFFLAFALPFVVITAAYVRILQR 303
Query: 230 LHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAIS 289
+ + + +++ KRVT +AI V +CW PY++ + L+ P V +
Sbjct: 304 MTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYN 363
Query: 290 YFITSLSYANSCLNPFLYAFLDASFRRNL 318
I SL YANSCLNPF+Y L +FR+ L
Sbjct: 364 AAI-SLGYANSCLNPFVYIVLCETFRKRL 391
>gi|7706103 relaxin/insulin-like family peptide receptor 3 [Homo
sapiens]
Length = 469
Score = 146 bits (368), Expect = 3e-35
Identities = 112/371 (30%), Positives = 165/371 (44%), Gaps = 57/371 (15%)
Query: 3 NASFSEP---WPANASGPDPALSC----SNASTLAPLPAPLAVAVPVVYAVICAVGLAGN 55
NAS P W PD A S + A A + + + VVY V+CA+GLAGN
Sbjct: 40 NASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGN 99
Query: 56 SAVLYVLLRAPRM-KTVTNLFILNLAIADELFTLVLPI----NIADFLLRQWPFGELMCK 110
VLY++ K+ NLF+ NLA+ D F L LP N DF +WPFG+ MCK
Sbjct: 100 LLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDF---KWPFGKAMCK 156
Query: 111 LIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYS-------------AARA 157
++ + N ++S++FLT MS RY V + +S R G +A+A
Sbjct: 157 IVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKA 216
Query: 158 VSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFP-----QPEAFWWRASRLYTLVLGF 212
+ + +W + L LP A+F+ G C++ FP + FW ++LGF
Sbjct: 217 LCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGF 276
Query: 213 AIPVSTICVLYTTLLCRLHAMRLDSHAK------------ALERAKKRVTFLVVAILAVC 260
+P+ I + Y LL R A R + K A R +VT V ++
Sbjct: 277 VLPLGIIILCY-LLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSF 335
Query: 261 LLCWTPYHLSTVVALTTDLPQTPLVIAISYFI---------TSLSYANSCLNPFLYAFLD 311
LCW P T ++ P + YF+ L+++NSCLNP LY +
Sbjct: 336 FLCWLPNQALTTWSILIKFNAVP--FSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVR 393
Query: 312 ASFRRNLRQLI 322
FR+ L+ L+
Sbjct: 394 REFRKALKSLL 404
>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
Length = 398
Score = 145 bits (365), Expect = 6e-35
Identities = 116/341 (34%), Positives = 164/341 (48%), Gaps = 29/341 (8%)
Query: 3 NASFSEPWPANASGPDPALSCSNASTLAPLPAPLAV---AVPVVYAVICAVGLAGNSAVL 59
NAS+ P ANASG C ++ P+P+P AV VP+ +A + +GL GNS V+
Sbjct: 10 NASWGAP--ANASG---CPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVI 64
Query: 60 YVLLRAPRMKTVTNLFILNLAIADELFTL-VLPINIADFLLRQWPFGELMCKLIVAIDQY 118
YV+ R M+TVTN +I NLA D F L +P + L W G+ MCK + I Q
Sbjct: 65 YVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQV 124
Query: 119 NTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFAR 178
+ ++ LT MS DR+ V + R + RT A AVSL++W V P R
Sbjct: 125 SVQATCATLTAMSVDRWYVTVFPL--RALHRRTPRLALAVSLSIWVGSAAVSAPVLALHR 182
Query: 179 LDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLH--AMRLD 236
L R C FP RA LY L+ + +P+ C Y +L L A+R
Sbjct: 183 LSPGP-RAYCSEAFPSRAL--ERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPA 239
Query: 237 SHAKAL------ERA---KKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDL----PQTP 283
AL ERA + +V+ LV A++ + CW P L V+ P++
Sbjct: 240 PADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSY 299
Query: 284 LVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITC 324
A+ + +SY+NS LNP LYAFL + FR+ R++ C
Sbjct: 300 AAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 144 bits (362), Expect = 1e-34
Identities = 94/289 (32%), Positives = 140/289 (48%), Gaps = 7/289 (2%)
Query: 35 PLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLV-LPIN 93
P AV VP+++A+I VG GN+ VL VLLR + + TNLFILNL +AD F L +P
Sbjct: 23 PEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQ 82
Query: 94 IADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYS 153
+ L W FG L+CK + + +S + L +S DRYL + SR + RT
Sbjct: 83 ATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSREL--RTPR 140
Query: 154 AARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFA 213
A A +WG+ L P+ + R C + P RA + T V +
Sbjct: 141 NALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRR---RAMDICTFVFSYL 197
Query: 214 IPVSTICVLYTTLLCRL-HAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTV 272
+PV + + Y L L A+ + RAK++VT +++ + A+ LCW P+H +
Sbjct: 198 LPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALIL 257
Query: 273 VALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQL 321
P T A+ +SYANSC+NP +YA + FR+ R +
Sbjct: 258 CVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTI 306
>gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens]
Length = 355
Score = 141 bits (356), Expect = 7e-34
Identities = 86/301 (28%), Positives = 152/301 (50%), Gaps = 23/301 (7%)
Query: 37 AVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIAD 96
A +P +Y+++ +GL GN V+ VL++ R+K +T++++LNLAI+D LF LP I
Sbjct: 34 AQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDY 93
Query: 97 FLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAAR 156
L W FG+ MCK++ +S ++F+ +++ DRYL ++ + R RT +
Sbjct: 94 KLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALR--ARTVTFGV 151
Query: 157 AVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTL-VLGFAIP 215
S+ +W + L +P F++ E C L FP W+ + L + G +P
Sbjct: 152 ITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLP 211
Query: 216 VSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVAL 275
+ + + YT ++ L + +KA+ L+ I+ + L WTPY+L+ ++++
Sbjct: 212 LLVMIICYTGIIKILLRRPNEKKSKAVR--------LIFVIMIIFFLFWTPYNLTILISV 263
Query: 276 TTDLPQT---------PLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRA 326
D T L + ++ I +Y + C+NP +YAF+ FR+ LRQL R
Sbjct: 264 FQDFLFTHECEQSRHLDLAVQVTEVI---AYTHCCVNPVIYAFVGERFRKYLRQLFHRRV 320
Query: 327 A 327
A
Sbjct: 321 A 321
>gi|30581170 CC chemokine receptor 3 [Homo sapiens]
Length = 355
Score = 141 bits (355), Expect = 9e-34
Identities = 84/309 (27%), Positives = 152/309 (49%), Gaps = 21/309 (6%)
Query: 18 DPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFIL 77
D L C A T A + A VP +Y+++ VGL GN V+ +L++ R++ +TN+++L
Sbjct: 19 DVGLLCEKADTRALM----AQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLL 74
Query: 78 NLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLV 137
NLAI+D LF + LP I W FG MCKL+ +S ++F+ +++ DRYL
Sbjct: 75 NLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLA 134
Query: 138 VLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEA 197
++ + R RT + S+ WG+ L LP +F ++ C ++P+
Sbjct: 135 IVHAVFALR--ARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTV 192
Query: 198 FWWR-ASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAI 256
+ WR L + +P+ + + YT ++ L + + K + L+ I
Sbjct: 193 YSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTL--------LRCPSKKKYKAIRLIFVI 244
Query: 257 LAVCLLCWTPYHLSTV------VALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFL 310
+AV + WTPY+++ + + D ++ + + ++Y++ C+NP +YAF+
Sbjct: 245 MAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFV 304
Query: 311 DASFRRNLR 319
FR+ LR
Sbjct: 305 GERFRKYLR 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,226,762
Number of Sequences: 37866
Number of extensions: 462982
Number of successful extensions: 3553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 338
Number of HSP's successfully gapped in prelim test: 211
Number of HSP's that attempted gapping in prelim test: 2191
Number of HSP's gapped (non-prelim): 723
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.