Guide to the Human Genome
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Search of human proteins with 13386480

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13386480 Nedd4 family interacting protein 1 [Homo sapiens]
         (221 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13386480 Nedd4 family interacting protein 1 [Homo sapiens]         456   e-129
gi|239046738 Nedd4 family interacting protein 2 isoform 1 [Homo ...   246   8e-66
gi|239046743 Nedd4 family interacting protein 2 isoform 2 [Homo ...   201   3e-52
gi|22749117 hypothetical protein LOC152405 [Homo sapiens]              33   0.19 
gi|110347463 human immunodeficiency virus type I enhancer bindin...    31   0.73 
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi...    31   0.96 
gi|21539663 praja 1 isoform c [Homo sapiens]                           30   1.2  
gi|74048537 praja 1 isoform b [Homo sapiens]                           30   1.2  
gi|41281725 praja 1 isoform a [Homo sapiens]                           30   1.2  
gi|33356179 transcription termination factor, RNA polymerase I [...    30   1.6  
gi|154354979 myosin X [Homo sapiens]                                   30   1.6  
gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Ho...    29   2.8  
gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Ho...    29   2.8  
gi|239742265 PREDICTED: hypothetical protein XP_002342467 [Homo ...    29   3.6  
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     29   3.6  
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    28   4.7  
gi|22538470 eomesodermin [Homo sapiens]                                28   6.2  
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi...    28   6.2  
gi|38787970 tensin like C1 domain containing phosphatase isoform...    28   8.1  
gi|38787957 tensin like C1 domain containing phosphatase isoform...    28   8.1  
gi|38787941 tensin like C1 domain containing phosphatase isoform...    28   8.1  
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           28   8.1  

>gi|13386480 Nedd4 family interacting protein 1 [Homo sapiens]
          Length = 221

 Score =  456 bits (1173), Expect = e-129
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESG 60
           MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESG
Sbjct: 1   MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESG 60

Query: 61  FPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFML 120
           FPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFML
Sbjct: 61  FPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFML 120

Query: 121 TFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWL 180
           TFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWL
Sbjct: 121 TFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWL 180

Query: 181 WWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY 221
           WWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY
Sbjct: 181 WWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY 221


>gi|239046738 Nedd4 family interacting protein 2 isoform 1 [Homo
           sapiens]
          Length = 336

 Score =  246 bits (629), Expect = 8e-66
 Identities = 132/238 (55%), Positives = 155/238 (65%), Gaps = 30/238 (12%)

Query: 12  EPACGSRYQQLQNEEESGEPE---------------QAAGDAP--------PPYSSISAE 48
           +P  G RYQ L NEE++ E                 QAA  AP        PPYSSI+ E
Sbjct: 99  QPGTG-RYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVE 157

Query: 49  SAAYFDYKDESGF-PKPPSYNVATTLPSYDEAERTKAEATIPLVPG-----RDEDFVGRD 102
                D +    F P PP Y+VAT+LP+YDEAE+ KA A            ++E+   RD
Sbjct: 158 VPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRD 217

Query: 103 DFDDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWIL 162
           DF DADQLR+GNDGIFML FFMAF+FNW+GF LSFC+T + AGRYGAI GFGLSLIKWIL
Sbjct: 218 DFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWIL 277

Query: 163 IVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFI 220
           IVRFS YF GYF+GQYWLWW+FLVLG LLF RGF+NY KVR M E+ +   RTR  F+
Sbjct: 278 IVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFL 335


>gi|239046743 Nedd4 family interacting protein 2 isoform 2 [Homo
           sapiens]
          Length = 316

 Score =  201 bits (512), Expect = 3e-52
 Identities = 118/238 (49%), Positives = 137/238 (57%), Gaps = 50/238 (21%)

Query: 12  EPACGSRYQQLQNEEESGEPE---------------QAAGDAP--------PPYSSISAE 48
           +P  G RYQ L NEE++ E                 QAA  AP        PPYSSI+ E
Sbjct: 99  QPGTG-RYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVE 157

Query: 49  SAAYFDYKDESGF-PKPPSYNVATTLPSYDEAERTKAEATIPLVPG-----RDEDFVGRD 102
                D +    F P PP Y+VAT+LP+YDEAE+ KA A            ++E+   RD
Sbjct: 158 VPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRD 217

Query: 103 DFDDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWIL 162
           DF DADQLR+GNDGIFML FF                     GRYGAI GFGLSLIKWIL
Sbjct: 218 DFSDADQLRVGNDGIFMLAFF--------------------TGRYGAICGFGLSLIKWIL 257

Query: 163 IVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFI 220
           IVRFS YF GYF+GQYWLWW+FLVLG LLF RGF+NY KVR M E+ +   RTR  F+
Sbjct: 258 IVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFL 315


>gi|22749117 hypothetical protein LOC152405 [Homo sapiens]
          Length = 536

 Score = 33.1 bits (74), Expect = 0.19
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 24  NEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTK 83
           N + S E E       PPY+ + A   + F  KD++ FP+ PS  + + L      E+T+
Sbjct: 403 NSKPSVEMETQNATTIPPYNPVDARFTSNFQAKDQALFPRLPS--ILSKLNYTSSQEKTQ 460

Query: 84  AEAT 87
           A  T
Sbjct: 461 AIVT 464


>gi|110347463 human immunodeficiency virus type I enhancer binding
            protein 2 [Homo sapiens]
          Length = 2446

 Score = 31.2 bits (69), Expect = 0.73
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 29   GEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATI 88
            G P    G    PY S+  +    +++   S FP+ P+  V + LP + + +     A I
Sbjct: 2170 GPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQ---VRAPI 2226

Query: 89   PLVP 92
            P+VP
Sbjct: 2227 PMVP 2230


>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
           sapiens]
          Length = 363

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 36  GDAPPPYSSISA--ESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPG 93
           G + PP +S +A  ES+  F     SG   PP        PS + A  T  E+    VP 
Sbjct: 84  GTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSVPS 143

Query: 94  RDEDFVGRDDFDDADQLRIGNDGIFMLTFFMA 125
                 GR++ D A  L  G++   MLT  M+
Sbjct: 144 SGSS--GREE-DAASTLVTGSEYETMLTEIMS 172


>gi|21539663 praja 1 isoform c [Homo sapiens]
          Length = 455

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 11/122 (9%)

Query: 8   LAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAE---------SAAYFDYKDE 58
           +AA+     SR Q L +  ES E      +  PP + +SA          SA+       
Sbjct: 184 IAALRRKYRSREQTLSSSGESWETLPGKEEREPPQAKVSASTGTSPGPGASASAGAGAGA 243

Query: 59  SGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIF 118
           S      +Y      PS  E + +  E  IP +   + D     D D   +L     G+F
Sbjct: 244 SAGSNGSNYLEEVREPSLQEEQASLEEGEIPWLQYHENDSSSEGDNDSGHELM--QPGVF 301

Query: 119 ML 120
           ML
Sbjct: 302 ML 303


>gi|74048537 praja 1 isoform b [Homo sapiens]
          Length = 588

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 11/122 (9%)

Query: 8   LAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAE---------SAAYFDYKDE 58
           +AA+     SR Q L +  ES E      +  PP + +SA          SA+       
Sbjct: 317 IAALRRKYRSREQTLSSSGESWETLPGKEEREPPQAKVSASTGTSPGPGASASAGAGAGA 376

Query: 59  SGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIF 118
           S      +Y      PS  E + +  E  IP +   + D     D D   +L     G+F
Sbjct: 377 SAGSNGSNYLEEVREPSLQEEQASLEEGEIPWLQYHENDSSSEGDNDSGHELM--QPGVF 434

Query: 119 ML 120
           ML
Sbjct: 435 ML 436


>gi|41281725 praja 1 isoform a [Homo sapiens]
          Length = 643

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 11/122 (9%)

Query: 8   LAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAE---------SAAYFDYKDE 58
           +AA+     SR Q L +  ES E      +  PP + +SA          SA+       
Sbjct: 372 IAALRRKYRSREQTLSSSGESWETLPGKEEREPPQAKVSASTGTSPGPGASASAGAGAGA 431

Query: 59  SGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIF 118
           S      +Y      PS  E + +  E  IP +   + D     D D   +L     G+F
Sbjct: 432 SAGSNGSNYLEEVREPSLQEEQASLEEGEIPWLQYHENDSSSEGDNDSGHELM--QPGVF 489

Query: 119 ML 120
           ML
Sbjct: 490 ML 491


>gi|33356179 transcription termination factor, RNA polymerase I
           [Homo sapiens]
          Length = 905

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 24  NEEESGEPEQAAGDAPPPY--SSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDE 78
           NE +  +   A GD PP Y  +  S   A Y  +  +  FP+   Y   TTLP   E
Sbjct: 781 NEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKE 837


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 27/109 (24%), Positives = 41/109 (37%), Gaps = 15/109 (13%)

Query: 33   QAAGDAPPP----------YSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERT 82
            Q AGD P P          Y   +  S +   + +  G    P Y  +    +   A R 
Sbjct: 1077 QNAGDLPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRF 1136

Query: 83   KAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIF---MLTFFMAFLF 128
             +E         +EDF  R  FD  D+L    D ++    L +F +FL+
Sbjct: 1137 SSEGAQSSFEDSEEDFDSR--FDTDDELSYRRDSVYSCVTLPYFHSFLY 1183


>gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 12/42 (28%), Positives = 22/42 (52%)

Query: 151 SGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF 192
           + F LS + WI +  F  +FP      ++  ++F ++ FL F
Sbjct: 219 TAFLLSSVFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYF 260


>gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Homo
           sapiens]
          Length = 622

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 12/42 (28%), Positives = 22/42 (52%)

Query: 151 SGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLF 192
           + F LS + WI +  F  +FP      ++  ++F ++ FL F
Sbjct: 349 TAFLLSSVFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYF 390


>gi|239742265 PREDICTED: hypothetical protein XP_002342467 [Homo
           sapiens]
          Length = 154

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 62  PKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGI 117
           P PP   +   L S+ +  + +     PL PG D+DF+  DDF  A  L  GND +
Sbjct: 85  PSPPQ-PMNKVLGSHPQRLQNEVHTASPLHPGGDDDFL--DDFGVARGL--GNDNV 135


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 8/70 (11%)

Query: 25  EEESGEPEQAAGD-----APPPYSSISAESAAYFDYKDESGFP---KPPSYNVATTLPSY 76
           EEE GE E+A G      +PP   + S E  A    K+E+  P   K P    A +    
Sbjct: 485 EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV 544

Query: 77  DEAERTKAEA 86
              E+ K+ A
Sbjct: 545 KSPEKAKSPA 554


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 13/79 (16%)

Query: 20   QQLQNEEESGEPEQAAGDA-------------PPPYSSISAESAAYFDYKDESGFPKPPS 66
            ++ + EEE GE E+  G+               P  S+   +SA   D+++E    + PS
Sbjct: 1360 EEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPS 1419

Query: 67   YNVATTLPSYDEAERTKAE 85
            +N        D++    AE
Sbjct: 1420 HNEDHDADDEDDSHMESAE 1438


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score = 28.1 bits (61), Expect = 6.2
 Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 5/66 (7%)

Query: 2   ALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGF 61
           A A AA AA   A  +RY       +S   E+    +P P  S  A   + F Y+  +G 
Sbjct: 117 AAAAAAAAAAAAAATARYSM-----DSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGA 171

Query: 62  PKPPSY 67
           P  P Y
Sbjct: 172 PHGPVY 177


>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
           sapiens]
          Length = 1771

 Score = 28.1 bits (61), Expect = 6.2
 Identities = 28/110 (25%), Positives = 43/110 (39%), Gaps = 21/110 (19%)

Query: 126 FLFNWIGFFLSFCLTTSAAGRYGAISGF----------GLSLIKWILIVRFSTYFPGYFD 175
           F F+W+  FL+  L     G  G +  F           LS +  + I     YF G  +
Sbjct: 495 FQFSWLIVFLTLLL----CGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYFGGRRE 550

Query: 176 GQYWLW-WVFLV-----LGFLLFLRGFINYAKVRKMPETFSNLPRTRVLF 219
           G+ W W WV        +G+L  L   + +    ++PE  +     R LF
Sbjct: 551 GESWNWAWVLSTRLARHIGYLELLLKLM-FVNPPELPEQTTKALPVRFLF 599


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 27.7 bits (60), Expect = 8.1
 Identities = 13/37 (35%), Positives = 18/37 (48%)

Query: 13  PACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAES 49
           P  GS Y Q+Q       P  +    PPP  S+S++S
Sbjct: 353 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDS 389


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score = 27.7 bits (60), Expect = 8.1
 Identities = 13/37 (35%), Positives = 18/37 (48%)

Query: 13  PACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAES 49
           P  GS Y Q+Q       P  +    PPP  S+S++S
Sbjct: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDS 513


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
           [Homo sapiens]
          Length = 1419

 Score = 27.7 bits (60), Expect = 8.1
 Identities = 13/37 (35%), Positives = 18/37 (48%)

Query: 13  PACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAES 49
           P  GS Y Q+Q       P  +    PPP  S+S++S
Sbjct: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDS 523


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 27.7 bits (60), Expect = 8.1
 Identities = 18/53 (33%), Positives = 20/53 (37%), Gaps = 5/53 (9%)

Query: 23  QNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPS 75
           QN   S     AA  APP +  I          K E   P PP  +V  T PS
Sbjct: 444 QNTSPSSPAAPAASSAPPMFKPIFTAPP-----KSEKEGPTPPGPSVTATAPS 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,917,382
Number of Sequences: 37866
Number of extensions: 404509
Number of successful extensions: 2000
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1979
Number of HSP's gapped (non-prelim): 26
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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