Guide to the Human Genome
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Search of human proteins with 13376759

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13376759 hypothetical protein LOC80231 [Homo sapiens]
         (301 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13376759 hypothetical protein LOC80231 [Homo sapiens]              593   e-170
gi|115527120 nebulin [Homo sapiens]                                    32   0.69 
gi|188497718 catenin, alpha 3 [Homo sapiens]                           31   1.2  
gi|188497716 catenin, alpha 3 [Homo sapiens]                           31   1.2  
gi|89941470 ankyrin repeat domain 34 [Homo sapiens]                    30   2.0  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 30   2.6  
gi|169212026 PREDICTED: keratin associated protein [Homo sapiens]      30   3.4  
gi|169211819 PREDICTED: keratin associated protein [Homo sapiens]      30   3.4  
gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo ...    30   3.4  
gi|56550051 ubiquitin specific protease 39 [Homo sapiens]              30   3.4  
gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...    29   5.8  
gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...    29   5.8  
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           29   5.8  
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           29   5.8  
gi|12707562 period 2 [Homo sapiens]                                    28   7.6  
gi|157426879 nuclear protein localization 4 [Homo sapiens]             28   7.6  
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s...    28   7.6  
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s...    28   9.9  
gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi...    28   9.9  
gi|98986331 pentatricopeptide repeat domain 2 [Homo sapiens]           28   9.9  
gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]         28   9.9  

>gi|13376759 hypothetical protein LOC80231 [Homo sapiens]
          Length = 301

 Score =  593 bits (1529), Expect = e-170
 Identities = 301/301 (100%), Positives = 301/301 (100%)

Query: 1   MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKS 60
           MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKS
Sbjct: 1   MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKS 60

Query: 61  SGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSI 120
           SGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSI
Sbjct: 61  SGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSI 120

Query: 121 CKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKP 180
           CKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKP
Sbjct: 121 CKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKP 180

Query: 181 IQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQIL 240
           IQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQIL
Sbjct: 181 IQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQIL 240

Query: 241 ASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVN 300
           ASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVN
Sbjct: 241 ASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVN 300

Query: 301 P 301
           P
Sbjct: 301 P 301


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 32.0 bits (71), Expect = 0.69
 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 12/89 (13%)

Query: 6    YLSGLEYWNDIHW--------SCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVS 57
            Y + LE+   I W        + A +   +  EK+  T  + TL+++ VD+   R  YV+
Sbjct: 4112 YKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTK-IETLNFTPVDD---RVDYVT 4167

Query: 58   CKSSGKFISSVHSRESQHSRSQRVTVLQT 86
             K SG+ +  +  R+  ++   + T+ +T
Sbjct: 4168 AKQSGEILDDIKYRKDWNATKSKYTLTET 4196


>gi|188497718 catenin, alpha 3 [Homo sapiens]
          Length = 895

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 189 RITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTS 248
           R+  +  + + Q  +P     L  YLEQ     ++  I   V    +  Q L  ELIM++
Sbjct: 744 RMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQV---KAEIQNLGGELIMSA 800

Query: 249 VDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPS 290
           +D ++  +   KNL  +  + +   ++  + ST+I  I +P+
Sbjct: 801 LDSVTSLIQAAKNLMNAVVQTV---KMSYIASTKIIRIQSPA 839


>gi|188497716 catenin, alpha 3 [Homo sapiens]
          Length = 895

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 189 RITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTS 248
           R+  +  + + Q  +P     L  YLEQ     ++  I   V    +  Q L  ELIM++
Sbjct: 744 RMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQV---KAEIQNLGGELIMSA 800

Query: 249 VDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPS 290
           +D ++  +   KNL  +  + +   ++  + ST+I  I +P+
Sbjct: 801 LDSVTSLIQAAKNLMNAVVQTV---KMSYIASTKIIRIQSPA 839


>gi|89941470 ankyrin repeat domain 34 [Homo sapiens]
          Length = 496

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 32/140 (22%), Positives = 52/140 (37%), Gaps = 15/140 (10%)

Query: 47  DETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDA 106
           D   + +L  +CK+ G  +  + +  S     +    L + P+P  E P  A+       
Sbjct: 123 DRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPASPS----- 177

Query: 107 SRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPME 166
                  P  C S  +        GG+ M       +      FE+ PL K  + P P E
Sbjct: 178 -------PGFCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEF-PLPKPPDDPSPSE 229

Query: 167 DSISTQPSDFPQKPIQRYSS 186
                +P   P KP++R +S
Sbjct: 230 P--LPKPPRHPPKPLKRLNS 247


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 3    SEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSG 62
            +EG    L    + H S   + E+   +  EE+  V +      DE +  S  V   +  
Sbjct: 2076 AEGVEPALGNEKEAHRSTPPFPEE---KPLEESKMVQSKVIDDADEGKKPSPEVKIPTQR 2132

Query: 63   KFISSVHSRESQHSRSQRVT 82
            K ISS+H+RE Q   S  VT
Sbjct: 2133 KPISSIHAREPQSPESPEVT 2152


>gi|169212026 PREDICTED: keratin associated protein [Homo sapiens]
          Length = 517

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 81  VTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSIC 121
           V+   T+  P+  SP  +A  ICR     T+ +PSS K  C
Sbjct: 347 VSCPSTSCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPC 387


>gi|169211819 PREDICTED: keratin associated protein [Homo sapiens]
          Length = 517

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 81  VTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSIC 121
           V+   T+  P+  SP  +A  ICR     T+ +PSS K  C
Sbjct: 347 VSCPSTSCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPC 387


>gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo
           sapiens]
          Length = 517

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 81  VTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSIC 121
           V+   T+  P+  SP  +A  ICR     T+ +PSS K  C
Sbjct: 347 VSCPSTSCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPC 387


>gi|56550051 ubiquitin specific protease 39 [Homo sapiens]
          Length = 565

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 195 EKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMD---TVFHDSSPTQ 238
           EK+   +  PI+N  L EYL ++V  ++K    D    + HD  P++
Sbjct: 465 EKNPTIVNFPITNVDLREYLSEEVQAVHKNTTYDLIANIVHDGKPSE 511


>gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 3/51 (5%)

Query: 3   SEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNS---VATLSYSSVDETQ 50
           S+G +SG   W+++   C S N   A  K+EE +S     TL+ + V + Q
Sbjct: 734 SKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQ 784


>gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 3/51 (5%)

Query: 3   SEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNS---VATLSYSSVDETQ 50
           S+G +SG   W+++   C S N   A  K+EE +S     TL+ + V + Q
Sbjct: 734 SKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQ 784


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 139 SVTTDFPSESSFEYGPLLKSS-EIPLPMEDSISTQPSDFPQKP 180
           S T DFP  S+ E   L +   ++P  + DS  T+P + P+ P
Sbjct: 323 STTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELP 365


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 28.9 bits (63), Expect = 5.8
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 139 SVTTDFPSESSFEYGPLLKSS-EIPLPMEDSISTQPSDFPQKP 180
           S T DFP  S+ E   L +   ++P  + DS  T+P + P+ P
Sbjct: 323 STTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELP 365


>gi|12707562 period 2 [Homo sapiens]
          Length = 1255

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 1/73 (1%)

Query: 17  HWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVH-SRESQH 75
           H   + Y    +    E   S  + S S+  E   R     CK+  K  +  H S ES  
Sbjct: 476 HSGSSGYGSLGSNGSHEHLMSQTSSSDSNGHEDSRRRRAEICKNGNKTKNRSHYSHESGE 535

Query: 76  SRSQRVTVLQTNP 88
            + + VT +QTNP
Sbjct: 536 QKKKSVTEMQTNP 548


>gi|157426879 nuclear protein localization 4 [Homo sapiens]
          Length = 608

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 15/185 (8%)

Query: 112 LVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSIST 171
           LV   C   CK+  +L  A  +  +      D   +   ++G  +     PLP+E  I  
Sbjct: 394 LVRDECLLPCKDAPELGYA--KESSSEQYVPDVFYKDVDKFGNEITQLARPLPVEYLIID 451

Query: 172 QPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVF 231
             + FP+ P+  +S       I+ +  L       +  L  YL Q    ++   I D  F
Sbjct: 452 ITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHS--LATYLSQNTSSVFLDTISD--F 507

Query: 232 HDSSPTQILASELIMTSVDQISLQV----SREKNLETSKARDIVFSRLLQLMSTEITEIS 287
           H       L +  +M   D ISL +    +R + L  +  R   ++ + QL ST   ++ 
Sbjct: 508 H---LLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQL- 563

Query: 288 TPSLH 292
            P LH
Sbjct: 564 -PGLH 567


>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
           sapiens]
          Length = 770

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 45/241 (18%)

Query: 31  KEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNP 90
           K++   S ++ S SS DE        S  SS    SS H R  +H R++     +++ + 
Sbjct: 469 KKKRRKSTSSSSVSSADE--------SVSSSSSSSSSGHKRHKKHKRNRS----ESSRSS 516

Query: 91  VFESPNLAAVEICRDASRETYLVPSSCKSICKN----------------YNDLQIAGGQV 134
              S   ++ +I ++   E Y VP++  +   N                Y   QI     
Sbjct: 517 RRHSSRASSNQIDQNRKDECYPVPANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDR 576

Query: 135 MAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQP-SDFPQKPIQRYSSYWRITSI 193
             ++S + + P +           SE P    +S  TQ  S   +KP   Y S    +S 
Sbjct: 577 CPLSSSSLEIPDDFG-------GRSEDPRDFYNSYKTQAGSSKTEKP---YKSERHFSSR 626

Query: 194 KEKSSLQMQNPISNAVLNEYLEQKV---VELYKQYIMDTVFHDSSPTQILASELIMTSVD 250
           +  S    +N           E+ +    E Y+++   +V H +SP    +SE    SV+
Sbjct: 627 RNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRRWEPGSVRHSTSPA---SSEYSWKSVE 683

Query: 251 Q 251
           +
Sbjct: 684 K 684


>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
           sapiens]
          Length = 738

 Score = 28.1 bits (61), Expect = 9.9
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 2/45 (4%)

Query: 48  ETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVF 92
           E Q R L   C++  + IS +H + S+ ++S+ VTV ++   P F
Sbjct: 196 EEQDRVLSFRCQA--RIISGIHMQTSESTKSELVTVTESFSTPKF 238


>gi|224809578 RAP1 GTPase activating protein isoform a [Homo
           sapiens]
          Length = 727

 Score = 28.1 bits (61), Expect = 9.9
 Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 14/97 (14%)

Query: 112 LVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSE--IPLPMEDSI 169
           LVPS   S+     DL         I  +      E    + P LK+ E  IP P    +
Sbjct: 47  LVPSYTPSLYPKNTDL------FEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEV 100

Query: 170 STQPSDFPQKPIQRYSSYW------RITSIKEKSSLQ 200
             +   FP   + ++  YW       ITSI E   LQ
Sbjct: 101 LGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQ 137


>gi|98986331 pentatricopeptide repeat domain 2 [Homo sapiens]
          Length = 388

 Score = 28.1 bits (61), Expect = 9.9
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 214 LEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSRE-KNLETSKARD--- 269
           LE+  VEL K   +   F DS+   IL   L +    + +LQV  E KN +    +D   
Sbjct: 145 LEESAVELMKDQHLRGFFSDSTSFNILMDMLFIKGKYKSALQVLIEMKNQDVKFTKDTYV 204

Query: 270 IVFSRLLQLMSTEITEIST 288
           + F+   +L S E  +I T
Sbjct: 205 LAFAICYKLNSPESFKICT 223


>gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]
          Length = 2354

 Score = 28.1 bits (61), Expect = 9.9
 Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 31/183 (16%)

Query: 13   WNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISS---VH 69
            W  IH++ ++ N   AG+ + +    A+    +V      + +     S  F+     +H
Sbjct: 2078 WVKIHFNRSNQNSS-AGDNDADGQGSASAPLMAVPARYGFNSHQGTSDSSLFLEESKVLH 2136

Query: 70   SRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQI 129
            +RE    R+ ++T L           N   V+I   + R   L   S K I         
Sbjct: 2137 ARELPKKRNFQLTFL-----------NHDVVKISPKSVRNKLLESQSKKKI--------- 2176

Query: 130  AGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDS---ISTQPSDFPQKPIQRYSS 186
              G+ +  +S    FP +    Y P++   +     E     I T+PSD  +K I +YS 
Sbjct: 2177 -HGKRVTTSSNKLGFPKKV---YKPIILQQKPRKASEKQSIWIRTKPSDIIRKYISKYSV 2232

Query: 187  YWR 189
            + R
Sbjct: 2233 FLR 2235


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.124    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,621,076
Number of Sequences: 37866
Number of extensions: 435988
Number of successful extensions: 1092
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1084
Number of HSP's gapped (non-prelim): 22
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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