Guide to the Human Genome
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Search of human proteins with 13376259

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13376259 nucleoporin 85 [Homo sapiens]
         (656 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13376259 nucleoporin 85 [Homo sapiens]                            1313   0.0  
gi|4557565 excision repair cross-complementing rodent repair def...    34   0.49 
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]      33   0.83 
gi|9966877 golgi associated PDZ and coiled-coil motif containing...    32   1.9  
gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa...    31   3.2  
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa...    31   3.2  
gi|187937176 NACHT, leucine rich repeat and PYD containing 7 iso...    31   4.1  
gi|75709196 NACHT, leucine rich repeat and PYD containing 7 isof...    31   4.1  
gi|62868213 golgi associated PDZ and coiled-coil motif containin...    31   4.1  
gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens]    30   9.2  

>gi|13376259 nucleoporin 85 [Homo sapiens]
          Length = 656

 Score = 1313 bits (3399), Expect = 0.0
 Identities = 656/656 (100%), Positives = 656/656 (100%)

Query: 1   MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKD 60
           MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKD
Sbjct: 1   MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKD 60

Query: 61  VDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVA 120
           VDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVA
Sbjct: 61  VDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVA 120

Query: 121 IAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSL 180
           IAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSL
Sbjct: 121 IAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSL 180

Query: 181 SADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTM 240
           SADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTM
Sbjct: 181 SADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTM 240

Query: 241 PILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKEL 300
           PILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKEL
Sbjct: 241 PILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKEL 300

Query: 301 LSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQV 360
           LSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQV
Sbjct: 301 LSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQV 360

Query: 361 IKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLG 420
           IKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLG
Sbjct: 361 IKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLG 420

Query: 421 VDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRN 480
           VDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRN
Sbjct: 421 VDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRN 480

Query: 481 NRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGK 540
           NRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGK
Sbjct: 481 NRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGK 540

Query: 541 YREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYEL 600
           YREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYEL
Sbjct: 541 YREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYEL 600

Query: 601 MRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS 656
           MRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS
Sbjct: 601 MRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS 656


>gi|4557565 excision repair cross-complementing rodent repair
           deficiency, complementation group 6 [Homo sapiens]
          Length = 1493

 Score = 33.9 bits (76), Expect = 0.49
 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 11/74 (14%)

Query: 49  PSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSV 108
           PS   + +    VDVY Q + +      G+   LQ++D  +   SR SQLV V K YRSV
Sbjct: 85  PSAQALELQGLGVDVYDQDVLE-----QGV---LQQVDNAIHEASRASQLVDVEKEYRSV 136

Query: 109 ---IRACMEEMHQV 119
              + +C   + Q+
Sbjct: 137 LDDLTSCTTSLRQI 150


>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 1063

 Score = 33.1 bits (74), Expect = 0.83
 Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 587  QKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARA 646
            Q Q+   A + Y+L + L+ LT+R P  GE+ T++ Q   + + ++E+ +L  A +  + 
Sbjct: 993  QIQLPLLAARRYKLQKQLDSLTARTPSEGEAGTQRQQ--KLSSLQLELSKLDKAASHLQQ 1050

Query: 647  IIREGSLEGS 656
            ++ E    GS
Sbjct: 1051 LMDEPPAPGS 1060


>gi|9966877 golgi associated PDZ and coiled-coil motif containing
           isoform a [Homo sapiens]
          Length = 462

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 28  GPG-EMLVCETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRID 86
           GP  E L  E   NKKEK +       + ++RK+ +   + +  L  E +G  L  + +D
Sbjct: 152 GPSVEELERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLD 211

Query: 87  EELTGKSRKSQLV 99
           +EL G+ ++ QL+
Sbjct: 212 KELAGRVQQIQLL 224


>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
           sapiens]
          Length = 687

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 7/76 (9%)

Query: 211 EARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQ 270
           E ++ L K  +ASP    +C    +L +      PG    L +L L  +HWH++C++ ++
Sbjct: 162 ELKRSLDK-TNASPGEFAVC--FTELQQKFFDNRPGK---LKDLILLIKHWHQQCQKKIK 215

Query: 271 DSTFATSPHLESLLKI 286
           D   + SP+   LL +
Sbjct: 216 DLP-SLSPYALELLTV 230


>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
           sapiens]
          Length = 719

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 7/76 (9%)

Query: 211 EARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQ 270
           E ++ L K  +ASP    +C    +L +      PG    L +L L  +HWH++C++ ++
Sbjct: 162 ELKRSLDK-TNASPGEFAVC--FTELQQKFFDNRPGK---LKDLILLIKHWHQQCQKKIK 215

Query: 271 DSTFATSPHLESLLKI 286
           D   + SP+   LL +
Sbjct: 216 DLP-SLSPYALELLTV 230


>gi|187937176 NACHT, leucine rich repeat and PYD containing 7
           isoform 3 [Homo sapiens]
          Length = 1037

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 30/141 (21%)

Query: 339 ESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNM 398
           ES  E L  +++A F        KE SI L+N   V H +  L HC+ LQ          
Sbjct: 577 ESQEEELAKVVVAPF--------KEISIHLTNTSEVMHCSFSLKHCQDLQK--------- 619

Query: 399 REFLLLEYASGLFAHPSL-WQLGVDYFDYC-----PELGRV---SLELHIERIPLNTEQK 449
              L L+ A G+F    + ++L ++ F+ C     P   R    SL L  +   L +   
Sbjct: 620 ---LSLQVAKGVFLENYMDFELDIE-FERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNS 675

Query: 450 ALKVLRICEQRQMTEQVRSIC 470
            LK L + +       VR +C
Sbjct: 676 NLKFLEVKQSFLSDSSVRILC 696


>gi|75709196 NACHT, leucine rich repeat and PYD containing 7 isoform
           2 [Homo sapiens]
          Length = 980

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 30/141 (21%)

Query: 339 ESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNM 398
           ES  E L  +++A F        KE SI L+N   V H +  L HC+ LQ          
Sbjct: 577 ESQEEELAKVVVAPF--------KEISIHLTNTSEVMHCSFSLKHCQDLQK--------- 619

Query: 399 REFLLLEYASGLFAHPSL-WQLGVDYFDYC-----PELGRV---SLELHIERIPLNTEQK 449
              L L+ A G+F    + ++L ++ F+ C     P   R    SL L  +   L +   
Sbjct: 620 ---LSLQVAKGVFLENYMDFELDIE-FERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNS 675

Query: 450 ALKVLRICEQRQMTEQVRSIC 470
            LK L + +       VR +C
Sbjct: 676 NLKFLEVKQSFLSDSSVRILC 696


>gi|62868213 golgi associated PDZ and coiled-coil motif containing
           isoform b [Homo sapiens]
          Length = 454

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 18/64 (28%), Positives = 34/64 (53%)

Query: 36  ETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRK 95
           E   NKKEK +       + ++RK+ +   + +  L  E +G  L  + +D+EL G+ ++
Sbjct: 153 ELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQ 212

Query: 96  SQLV 99
            QL+
Sbjct: 213 IQLL 216


>gi|55742695 sterile alpha motif domain containing 4B [Homo sapiens]
          Length = 694

 Score = 29.6 bits (65), Expect = 9.2
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

Query: 231 RIMGDLMRTMPILSPGNTQTLTE---LELKWQHWHEECERYLQDSTFATSPHLESLLKIM 287
           +++  L+  +P+L PGNT+  +E   L  K   +  E   ++++S          LL   
Sbjct: 78  KVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEES--------RQLLSYA 129

Query: 288 LGDEAALLEQKELLSNWYHFLVTRL 312
           L   A  LE +  L+ W   L  RL
Sbjct: 130 LIHPATTLEDRNALALWLSHLEERL 154


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,801,989
Number of Sequences: 37866
Number of extensions: 1017837
Number of successful extensions: 2407
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2400
Number of HSP's gapped (non-prelim): 13
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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