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Search of human proteins with 50845409
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50845409 derlin 3 isoform 3 [Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209364542 derlin 3 isoform 1 [Homo sapiens] 417 e-117
gi|50845411 derlin 3 isoform 2 [Homo sapiens] 417 e-117
gi|50845409 derlin 3 isoform 3 [Homo sapiens] 417 e-117
gi|31455614 Der1-like domain family, member 2 [Homo sapiens] 345 1e-95
gi|13236516 Der1-like domain family, member 1 isoform a [Homo sa... 144 5e-35
gi|197927278 Der1-like domain family, member 1 isoform b [Homo s... 116 1e-26
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens] 33 0.22
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 29 2.4
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 29 2.4
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 29 2.4
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 29 2.4
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 28 4.2
gi|122937259 solute carrier family 45, member 4 [Homo sapiens] 28 7.1
>gi|209364542 derlin 3 isoform 1 [Homo sapiens]
Length = 239
Score = 417 bits (1071), Expect = e-117
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
Sbjct: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
Query: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
Sbjct: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
Query: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
Query: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
IYYFLEDVFPNQPGGKRLLQTPGFL
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
>gi|50845411 derlin 3 isoform 2 [Homo sapiens]
Length = 235
Score = 417 bits (1071), Expect = e-117
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
Sbjct: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
Query: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
Sbjct: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
Query: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
Query: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
IYYFLEDVFPNQPGGKRLLQTPGFL
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
>gi|50845409 derlin 3 isoform 3 [Homo sapiens]
Length = 205
Score = 417 bits (1071), Expect = e-117
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
Sbjct: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
Query: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
Sbjct: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
Query: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
Sbjct: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
Query: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
IYYFLEDVFPNQPGGKRLLQTPGFL
Sbjct: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
>gi|31455614 Der1-like domain family, member 2 [Homo sapiens]
Length = 239
Score = 345 bits (886), Expect = 1e-95
Identities = 162/205 (79%), Positives = 183/205 (89%)
Query: 1 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 60
MA+Q L E+LQ+P V+RAYT ACVLTTAAVQLEL++PFQLYFNP L+F+ FQ+WRL+TN
Sbjct: 1 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 60
Query: 61 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 120
FLFFGP+GF+F FNM+F++RYCRMLEEGSFRGRTADFVFMFLFGG LMTL GL SL FL
Sbjct: 61 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 120
Query: 121 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 180
GQA MLVYVWSRR+P VR+NFFGLL FQAPFLPW LMGFSLLLGNSI+VDLLGIAVGH
Sbjct: 121 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 180
Query: 181 IYYFLEDVFPNQPGGKRLLQTPGFL 205
IY+FLEDVFPNQPGG R+L+TP L
Sbjct: 181 IYFFLEDVFPNQPGGIRILKTPSIL 205
>gi|13236516 Der1-like domain family, member 1 isoform a [Homo
sapiens]
Length = 251
Score = 144 bits (363), Expect = 5e-35
Identities = 73/199 (36%), Positives = 119/199 (59%), Gaps = 3/199 (1%)
Query: 10 FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66
F +PA+TR + AA V +L L+SP L+ P +FQ+WR +T +F GP
Sbjct: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
Query: 67 LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126
GF + N+ F+++Y LE G+F GR AD++FM LF + + + GL + L L+
Sbjct: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
Query: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186
++YVW++ + + V+F+ F+A +LPW ++GF+ ++G S++ +L+G VGH+Y+FL
Sbjct: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
Query: 187 DVFPNQPGGKRLLQTPGFL 205
+P GG+ L TP FL
Sbjct: 188 FRYPMDLGGRNFLSTPQFL 206
>gi|197927278 Der1-like domain family, member 1 isoform b [Homo
sapiens]
Length = 231
Score = 116 bits (291), Expect = 1e-26
Identities = 65/189 (34%), Positives = 106/189 (56%), Gaps = 3/189 (1%)
Query: 10 FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66
F +PA+TR + AA V +L L+SP L+ P +FQ+WR +T +F GP
Sbjct: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
Query: 67 LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126
GF + N+ F+++Y LE G+F GR AD++FM LF + + + GL + L L+
Sbjct: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
Query: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186
++YVW++ + + V+F+ F+A +LPW ++GF+ ++G S +DL G FL
Sbjct: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187
Query: 187 DVFPNQPGG 195
P++ GG
Sbjct: 188 RWLPSRRGG 196
>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
Length = 360
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 21 TAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFFGPL-GFSFFFNMLFVF 79
TA VL T L LLS + +L+ Q+ R ++LF G L G F +++F
Sbjct: 34 TAVAVLCTL---LGLLSALENVAVLYLILSSHQL-RRKPSYLFIGSLAGADFLASVVFA- 88
Query: 80 RYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSL 117
C + F G + VF+ G V MT +GSL
Sbjct: 89 --CSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSL 124
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 29.3 bits (64), Expect = 2.4
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 59 TNFLFFGPLGFSFFFNMLFVFRYCRMLE---EGSFRGRTADFVFMFLFGGVLMTLLGLLG 115
T++++ GP+ N +F+F R+L S T + VL+ LLG+
Sbjct: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327
Query: 116 SLFFL--GQALMAMLVYVW 132
LFF+ G+ ++ +V+++
Sbjct: 328 MLFFVNPGEDEVSRVVFIY 346
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 29.3 bits (64), Expect = 2.4
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 59 TNFLFFGPLGFSFFFNMLFVFRYCRMLE---EGSFRGRTADFVFMFLFGGVLMTLLGLLG 115
T++++ GP+ N +F+F R+L S T + VL+ LLG+
Sbjct: 228 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 287
Query: 116 SLFFL--GQALMAMLVYVW 132
LFF+ G+ ++ +V+++
Sbjct: 288 MLFFVNPGEDEVSRVVFIY 306
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 29.3 bits (64), Expect = 2.4
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 59 TNFLFFGPLGFSFFFNMLFVFRYCRMLE---EGSFRGRTADFVFMFLFGGVLMTLLGLLG 115
T++++ GP+ N +F+F R+L S T + VL+ LLG+
Sbjct: 297 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 356
Query: 116 SLFFL--GQALMAMLVYVW 132
LFF+ G+ ++ +V+++
Sbjct: 357 MLFFVNPGEDEVSRVVFIY 375
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 29.3 bits (64), Expect = 2.4
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 59 TNFLFFGPLGFSFFFNMLFVFRYCRMLE---EGSFRGRTADFVFMFLFGGVLMTLLGLLG 115
T++++ GP+ N +F+F R+L S T + VL+ LLG+
Sbjct: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327
Query: 116 SLFFL--GQALMAMLVYVW 132
LFF+ G+ ++ +V+++
Sbjct: 328 MLFFVNPGEDEVSRVVFIY 346
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 28.5 bits (62), Expect = 4.2
Identities = 12/24 (50%), Positives = 18/24 (75%)
Query: 100 MFLFGGVLMTLLGLLGSLFFLGQA 123
+ +F GVL T++GL G++F L QA
Sbjct: 209 LVIFAGVLATIMGLYGAIFRLVQA 232
>gi|122937259 solute carrier family 45, member 4 [Homo sapiens]
Length = 798
Score = 27.7 bits (60), Expect = 7.1
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 5/51 (9%)
Query: 110 LLGLLGSLFFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMG 160
+LG LG F +G A+MAM V+ V ++ G+++ + P+AL+G
Sbjct: 544 VLGTLG--FSVGTAVMAMFPNVYVAM---VTISTMGIVSMSISYCPYALLG 589
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.336 0.149 0.482
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,278,610
Number of Sequences: 37866
Number of extensions: 281589
Number of successful extensions: 836
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 825
Number of HSP's gapped (non-prelim): 15
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.