Search of human proteins with 4885269

Search of human proteins with 4885269

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
[Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...   958   0.0  
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...   942   0.0  
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...   942   0.0  
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap...   417   e-116
gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap...   192   7e-49
gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Ho...   191   2e-48
gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Ho...   141   1e-33
gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 ...   130   2e-30
gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 ...   101   1e-21
gi|148231468 GDNF family receptor alpha like [Homo sapiens]            75   1e-13
gi|151301154 mucin 6, gastric [Homo sapiens]                           35   0.19 
gi|39930511 collagen and calcium binding EGF domains 1 [Homo sap...    31   2.1  
gi|126032338 ryanodine receptor 3 [Homo sapiens]                       31   2.1  
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]            30   3.6  
gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso...    30   6.1  
gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof...    30   6.1  
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]                29   7.9  

>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
           [Homo sapiens]
          Length = 465

 Score =  958 bits (2477), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60
           MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF
Sbjct: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60

Query: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120
           SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP
Sbjct: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120

Query: 121 YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 180
           YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT
Sbjct: 121 YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 180

Query: 181 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 240
           SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK
Sbjct: 181 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 240

Query: 241 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 300
           PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN
Sbjct: 241 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 300

Query: 301 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 360
           YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV
Sbjct: 301 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 360

Query: 361 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 420
           QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY
Sbjct: 361 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 420

Query: 421 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 465
           EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS
Sbjct: 421 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 465


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  942 bits (2435), Expect = 0.0
 Identities = 460/465 (98%), Positives = 460/465 (98%), Gaps = 5/465 (1%)

Query: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60
           MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF
Sbjct: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60

Query: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120
           SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP
Sbjct: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120

Query: 121 YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 180
           YEPVNSRLSDIFRVVPFIS     VEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT
Sbjct: 121 YEPVNSRLSDIFRVVPFIS-----VEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 175

Query: 181 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 240
           SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK
Sbjct: 176 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 235

Query: 241 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 300
           PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN
Sbjct: 236 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 295

Query: 301 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 360
           YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV
Sbjct: 296 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 355

Query: 361 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 420
           QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY
Sbjct: 356 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 415

Query: 421 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 465
           EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS
Sbjct: 416 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 460


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  942 bits (2435), Expect = 0.0
 Identities = 460/465 (98%), Positives = 460/465 (98%), Gaps = 5/465 (1%)

Query: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60
           MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF
Sbjct: 1   MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF 60

Query: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120
           SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP
Sbjct: 61  SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP 120

Query: 121 YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 180
           YEPVNSRLSDIFRVVPFIS     VEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT
Sbjct: 121 YEPVNSRLSDIFRVVPFIS-----VEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT 175

Query: 181 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 240
           SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK
Sbjct: 176 SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK 235

Query: 241 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 300
           PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN
Sbjct: 236 PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN 295

Query: 301 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 360
           YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV
Sbjct: 296 YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV 355

Query: 361 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 420
           QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY
Sbjct: 356 QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY 415

Query: 421 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 465
           EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS
Sbjct: 416 EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS 460


>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
           sapiens]
          Length = 464

 Score =  417 bits (1072), Expect = e-116
 Identities = 208/396 (52%), Positives = 275/396 (69%), Gaps = 16/396 (4%)

Query: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92

Query: 87  CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFISDVFQQV 145
           CRCKRGMKKE  CL+IYWS++  L +G +  E SPYEPV SRLSDIFR+    S      
Sbjct: 93  CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADP 152

Query: 146 EHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVS-NDVCNRRKCHKALRQFFDKVP 204
               K N+CLDAAKACNL+D CKK RS+YI+ C   +S  + CNRRKCHKALRQFFD+VP
Sbjct: 153 VVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVP 212

Query: 205 AKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 264
           ++++Y MLFCSC+D AC ERRRQTI+P CSYE++EKPNCL+L+  C+T+++CRSRLADF 
Sbjct: 213 SEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFH 272

Query: 265 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSS--SLSVAPWCDCSNSGNDL 322
            NC+   ++V+SC  +NY  CL +Y+G+IG  MTPNY+DSS   + V+PWC C  SGN  
Sbjct: 273 ANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNME 332

Query: 323 EECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLGP-- 380
           EEC KFL  F +N CL+NAIQAFGNG+DV V  P  P    +   T A RV+  P  P  
Sbjct: 333 EECEKFLRDFTENPCLRNAIQAFGNGTDVNV-SPKGP----SFQATQAPRVEKTPSLPDD 387

Query: 381 AGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCIS 416
                 + T V+  C ++Q Q LK+N S    +C +
Sbjct: 388 LSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFT 423


>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
           sapiens]
          Length = 400

 Score =  192 bits (487), Expect = 7e-49
 Identities = 119/319 (37%), Positives = 158/319 (49%), Gaps = 18/319 (5%)

Query: 29  CVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCR 88
           C++A  +C  + +CS  Y  L  C +   T           D C  A + L+  SL  C 
Sbjct: 44  CLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPAD-CLEAAQQLRNSSLIGCM 102

Query: 89  CKRGMKKEKNCLRIYWSMYQSLQ-GNDLLEDSPYEPVNSRLSDIFRVVPFISDVFQQVEH 147
           C R MK +  CL IYW+++++   GN  L+ SPYE       D     P+  ++ +    
Sbjct: 103 CHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYE-------DTVTSKPWKMNLSKLNML 155

Query: 148 IPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKH 207
            P  + CL  A  C L+D C + R AY   C    S   C R  C + L  FF+K    H
Sbjct: 156 KPDSDLCLKFAMLCTLNDKCDRLRKAYGEAC----SGPHCQRHVCLRQLLTFFEKAAEPH 211

Query: 208 SYGMLFCSC--RDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT 265
           + G+L C C   D  C ERRR TI P C+      PNCL L+  C ++ +CRSRL DF T
Sbjct: 212 AQGLLLCPCAPNDRGCGERRRNTIAPNCALPP-VAPNCLELRRLCFSDPLCRSRLVDFQT 270

Query: 266 NCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEEC 325
           +C P    + +C  E  + CL AY GLIGT MTPN++ + + SVA  C C  SGN  EEC
Sbjct: 271 HCHPMD-ILGTCATEQ-SRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEEC 328

Query: 326 LKFLNFFKDNTCLKNAIQA 344
                FF  N CL  AI A
Sbjct: 329 EMLEGFFSHNPCLTEAIAA 347


>gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Homo
           sapiens]
          Length = 269

 Score =  191 bits (484), Expect = 2e-48
 Identities = 91/208 (43%), Positives = 121/208 (58%), Gaps = 7/208 (3%)

Query: 151 GNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYG 210
           GN C+DAA+AC  D  C++ RS Y+  C    +   C R +C +ALR+FF + P   ++ 
Sbjct: 23  GNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHA 82

Query: 211 MLFCSCRDIACTERRRQTIVPVCSYEER--EKPNCLNLQDSCKTNYICRSRLADFFTNCQ 268
           +LFC C   AC ERRRQT VP C++       P+CL   + C+ + +CR RL  F  +C 
Sbjct: 83  LLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCT 142

Query: 269 PESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKF 328
           P   +   CL +  A CL AY+GL+GT +TPNY+D+ S  VAPWCDC  SGN  E+C  F
Sbjct: 143 PAPSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAF 202

Query: 329 LNFFKDNTCLKNAIQAFGNGSDVTVWQP 356
              F  N CL  AIQAF +G     W P
Sbjct: 203 RGLFTRNRCLDGAIQAFASG-----WPP 225


>gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Homo
           sapiens]
          Length = 299

 Score =  141 bits (355), Expect = 1e-33
 Identities = 82/238 (34%), Positives = 111/238 (46%), Gaps = 37/238 (15%)

Query: 151 GNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYG 210
           GN C+DAA+AC  D  C++ RS Y+  C    +   C R +C +ALR+FF + P   ++ 
Sbjct: 23  GNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHA 82

Query: 211 MLFCSCRDIACTERRRQTIVPVCSYE--EREKPNCLNLQDSCKTNYICRSRLA------D 262
           +LFC C   AC ERRRQT VP C++       P+CL   + C+ + +CR   A       
Sbjct: 83  LLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRG 142

Query: 263 FFTNCQPESRSVSSCLKENYADCLLAYSGL------------------------IGTVMT 298
           +     P  R  ++         L+  S                           GT +T
Sbjct: 143 WGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVT 202

Query: 299 PNYIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQP 356
           PNY+D+ S  VAPWCDC  SGN  E+C  F   F  N CL  AIQAF +G     W P
Sbjct: 203 PNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASG-----WPP 255


>gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 364

 Score =  130 bits (328), Expect = 2e-30
 Identities = 61/114 (53%), Positives = 84/114 (73%), Gaps = 6/114 (5%)

Query: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92

Query: 87  CRCKRGMKKEKNCLRIYWSMYQSL-QGNDLLEDSPYEPVNSRLSDIFRVVPFIS 139
           CRCKRGMKKE  CL+IYWS++  L +G +  E SPYEPV SRLSDIFR+    S
Sbjct: 93  CRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFS 146


>gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 140

 Score =  101 bits (252), Expect = 1e-21
 Identities = 44/84 (52%), Positives = 64/84 (76%), Gaps = 5/84 (5%)

Query: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92

Query: 87  CRCKRGMKKEKNCLRIYWSMYQSL 110
           CRCKRGMKKE  CL+IYWS++  L
Sbjct: 93  CRCKRGMKKELQCLQIYWSIHLGL 116


>gi|148231468 GDNF family receptor alpha like [Homo sapiens]
          Length = 394

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 17/160 (10%)

Query: 153 NCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGML 212
           +CL+ A+AC  D +C    ++Y+  C  S + + C+ ++C  A+R F+  +P   +  + 
Sbjct: 130 SCLEVAEACVGDVVCNAQLASYLKAC--SANGNPCDLKQCQAAIRFFYQNIPFNIAQMLA 187

Query: 213 FCSCR--DIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT----- 265
           FC C   DI C + +       C+      P CL++  SC+ + +CR     F +     
Sbjct: 188 FCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRSCQNDELCRRHYRTFQSKCWQR 247

Query: 266 ---NCQPESRSVSSCLKENYA-----DCLLAYSGLIGTVM 297
               C  +   +S+  K++       DC  AY  ++GTV+
Sbjct: 248 VTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTVL 287


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 27/121 (22%), Positives = 48/121 (39%), Gaps = 12/121 (9%)

Query: 356  PAFPVQTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQA---------QKLKSN 406
            P F     T +T T +   +  +  + S +  PT  +PP   L+A           + ++
Sbjct: 2010 PPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTS 2069

Query: 407  VSGNTHLCISNGNYEKEGLGASSHITTKSMAAPPSCGLS---PLLVLVVTALSTLLSLTE 463
             +  TH   S        + +SS +   S + PPS  ++   P L    T +ST   L+ 
Sbjct: 2070 GTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSS 2129

Query: 464  T 464
            +
Sbjct: 2130 S 2130


>gi|39930511 collagen and calcium binding EGF domains 1 [Homo
           sapiens]
          Length = 406

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 28/126 (22%), Positives = 51/126 (40%), Gaps = 30/126 (23%)

Query: 165 DICKKYRSAYIT-PCTTSVSN-DVCNRRKCHKALRQFFDK-VPAKH-------------- 207
           +IC + + A    PC  S      C R+KC K  +    + +P  +              
Sbjct: 45  EICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTD 104

Query: 208 SYGMLFCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTN-----YICRSRLAD 262
           ++G + C+C      +R R        + +REKP CL++ +   +N     +IC + L  
Sbjct: 105 NFGRVLCTCYPGYRYDRER--------HRKREKPYCLDIDECASSNGTLCAHICINTLGS 156

Query: 263 FFTNCQ 268
           +   C+
Sbjct: 157 YRCECR 162


>gi|126032338 ryanodine receptor 3 [Homo sapiens]
          Length = 4870

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 134  VVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICK-KYRSAYITPCTTSVSNDVCNRRKC 192
            VV  +  +     HIP+ N C+D  + C  +D+ +  Y +  +     ++ N       C
Sbjct: 1522 VVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSAVCALGNSRVAYALC 1581

Query: 193  -HKALRQFFDKVPAKHSYGML 212
             H  L Q F  +  K+  G+L
Sbjct: 1582 SHVDLSQLFYAIDNKYLPGLL 1602


>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 35/175 (20%), Positives = 63/175 (36%), Gaps = 16/175 (9%)

Query: 154 CLDAAKACNLDDICKKYRSAYIT-PCTTSVSNDVCNRRKCHKALRQFFDKVPAKHSYGML 212
           C  +++  +    C+  R++  +  C +S ++  C+   C  + R        + S    
Sbjct: 110 CCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCS---CQTS-RTSSTSCSYQSSRTSS 165

Query: 213 FCSCRDIACTERRRQTIVPVCSYEEREKPNCLNLQDS--CKTNYICRSRLADFFTNCQPE 270
            CSC+    +          C+++     +  + Q S    T+Y C+S       +CQ  
Sbjct: 166 TCSCQSSGTSSTS-------CNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSS 218

Query: 271 SRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEEC 325
             S +SC  ++            GT  T     SS  S    C C +SG     C
Sbjct: 219 GTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSST--CSCQSSGTSSTSC 271


>gi|75677329 WD repeat domain, phosphoinositide interacting 2
           isoform c [Homo sapiens]
          Length = 443

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 18/42 (42%), Positives = 21/42 (50%)

Query: 316 SNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPA 357
           S SG      L F NF +DNT +K A +A G G    VW  A
Sbjct: 5   SQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLA 46


>gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform
           a [Homo sapiens]
          Length = 454

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 18/42 (42%), Positives = 21/42 (50%)

Query: 316 SNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPA 357
           S SG      L F NF +DNT +K A +A G G    VW  A
Sbjct: 5   SQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLA 46


>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
          Length = 3144

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 8/65 (12%)

Query: 212 LFCSCRDIACTERRRQTIVPVC------SYEEREKPNCLNLQDSCKTNYICRSRLADFFT 265
           LF SC+D    E        +C      S  E E   C +  + CK N  C      FF 
Sbjct: 895 LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSS--EPCKNNGTCVDLTNRFFC 952

Query: 266 NCQPE 270
           NC+PE
Sbjct: 953 NCEPE 957


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,158,021
Number of Sequences: 37866
Number of extensions: 825067
Number of successful extensions: 2222
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2172
Number of HSP's gapped (non-prelim): 27
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.