Guide to the Human Genome
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Search of human proteins with 4885181

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885181 defensin, beta 1 preproprotein [Homo sapiens]
         (68 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885181 defensin, beta 1 preproprotein [Homo sapiens]              149   6e-37
gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo ...    34   0.022
gi|239743453 PREDICTED: hypothetical protein XP_002342852 [Homo ...    33   0.049
gi|4826692 defensin, beta 4 precursor [Homo sapiens]                   33   0.049
gi|62988324 tenascin N [Homo sapiens]                                  28   2.0  
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       27   2.7  
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...    27   3.5  
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...    27   3.5  
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...    27   3.5  
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ...    27   3.5  
gi|14042925 ring finger protein 26 [Homo sapiens]                      27   3.5  
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho...    26   5.9  
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    26   5.9  

>gi|4885181 defensin, beta 1 preproprotein [Homo sapiens]
          Length = 68

 Score =  149 bits (375), Expect = 6e-37
 Identities = 68/68 (100%), Positives = 68/68 (100%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY 60
          MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY
Sbjct: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY 60

Query: 61 RGKAKCCK 68
          RGKAKCCK
Sbjct: 61 RGKAKCCK 68


>gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo
          sapiens]
          Length = 87

 Score = 34.3 bits (77), Expect = 0.022
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 6  LLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAK 65
          L L  L LL S + S GN   GLG    H  C++  G C    C +     G C R K K
Sbjct: 3  LHLLLLILLFSILLSPGN-KGGLGPAEGH--CLNLSGVCRRDVCKVVEDQIGAC-RRKMK 58

Query: 66 CCK 68
          CC+
Sbjct: 59 CCR 61


>gi|239743453 PREDICTED: hypothetical protein XP_002342852 [Homo
          sapiens]
          Length = 64

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY 60
          MR  YLL   L + L  +        G+G   D   C+ SG  C    CP   K  GTC 
Sbjct: 1  MRVLYLLFSFLFIFLMPLPG---VFGGIG---DPVTCLKSGAICHPVFCPRRYKQIGTCG 54

Query: 61 RGKAKCCK 68
              KCCK
Sbjct: 55 LPGTKCCK 62


>gi|4826692 defensin, beta 4 precursor [Homo sapiens]
          Length = 64

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY 60
          MR  YLL   L + L  +        G+G   D   C+ SG  C    CP   K  GTC 
Sbjct: 1  MRVLYLLFSFLFIFLMPLPG---VFGGIG---DPVTCLKSGAICHPVFCPRRYKQIGTCG 54

Query: 61 RGKAKCCK 68
              KCCK
Sbjct: 55 LPGTKCCK 62


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/47 (34%), Positives = 17/47 (36%), Gaps = 9/47 (19%)

Query: 29  GHRSDHYNCVSS---------GGQCLYSACPIFTKIQGTCYRGKAKC 66
           G  S H  CV           G  C Y ACP      G C RG  +C
Sbjct: 173 GACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQC 219


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 10   TLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSAC 49
            TLC   +  A+ G+ LTG     D   C +  G C Y  C
Sbjct: 1050 TLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKC 1089


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
          [Homo sapiens]
          Length = 460

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCL-YSACPIFTKIQGTC 59
          + T Y  L  L LLLS   SGG          D  +CV +  QCL   +C    +    C
Sbjct: 3  LATLYFALPLLDLLLSAEVSGG----------DRLDCVKASDQCLKEQSCSTKYRTLRQC 52

Query: 60 YRGK 63
            GK
Sbjct: 53 VAGK 56


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
          [Homo sapiens]
          Length = 460

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCL-YSACPIFTKIQGTC 59
          + T Y  L  L LLLS   SGG          D  +CV +  QCL   +C    +    C
Sbjct: 3  LATLYFALPLLDLLLSAEVSGG----------DRLDCVKASDQCLKEQSCSTKYRTLRQC 52

Query: 60 YRGK 63
            GK
Sbjct: 53 VAGK 56


>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
          [Homo sapiens]
          Length = 465

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCL-YSACPIFTKIQGTC 59
          + T Y  L  L LLLS   SGG          D  +CV +  QCL   +C    +    C
Sbjct: 3  LATLYFALPLLDLLLSAEVSGG----------DRLDCVKASDQCLKEQSCSTKYRTLRQC 52

Query: 60 YRGK 63
            GK
Sbjct: 53 VAGK 56


>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
           sapiens]
          Length = 192

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 9/63 (14%)

Query: 6   LLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAK 65
           L+L    +LLS +         LG    H  C+S  G C    C +     G C R + K
Sbjct: 71  LILLLFSILLSPVRGA------LGPAEVH--CLSLSGVCRRDVCKVVEDQIGAC-RRRMK 121

Query: 66  CCK 68
           CC+
Sbjct: 122 CCR 124


>gi|14042925 ring finger protein 26 [Homo sapiens]
          Length = 433

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 21/57 (36%), Positives = 22/57 (38%), Gaps = 13/57 (22%)

Query: 8   LFTLCLLLSEMASGGNFLTGLGHRSDH-------------YNCVSSGGQCLYSACPI 51
           L  LC LL    SG   L  LGH + H              N VSSG   L  AC I
Sbjct: 80  LQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVLNVVSSGHALLRQACDI 136


>gi|4507065 secretory leukocyte peptidase inhibitor precursor [Homo
           sapiens]
          Length = 132

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 37  CVSSGGQCLYSACPIFTKIQGTCYRGKAKCC 67
           C  + GQCL    P F ++ G C R   KCC
Sbjct: 89  CPVTYGQCLMLNPPNFCEMDGQCKR-DLKCC 118


>gi|126012573 low density lipoprotein-related protein 2 [Homo
           sapiens]
          Length = 4655

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 13/40 (32%), Positives = 14/40 (35%), Gaps = 3/40 (7%)

Query: 30  HRSDHYNCVSSGGQ---CLYSACPIFTKIQGTCYRGKAKC 66
           +R DH      G     C Y  C   T   G CY    KC
Sbjct: 125 YRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKC 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,702,292
Number of Sequences: 37866
Number of extensions: 96144
Number of successful extensions: 285
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 279
Number of HSP's gapped (non-prelim): 14
length of query: 68
length of database: 18,247,518
effective HSP length: 41
effective length of query: 27
effective length of database: 16,695,012
effective search space: 450765324
effective search space used: 450765324
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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