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Search of human proteins with 4826802
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826802 potassium inwardly-rectifying channel J8 [Homo
sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 833 0.0
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 533 e-151
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 349 3e-96
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 341 8e-94
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 337 2e-92
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 335 6e-92
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 332 3e-91
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 329 3e-90
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 329 3e-90
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 329 3e-90
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 329 3e-90
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 320 2e-87
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 320 2e-87
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 320 2e-87
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 298 5e-81
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 298 5e-81
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 292 3e-79
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 292 3e-79
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 292 3e-79
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 292 3e-79
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 292 3e-79
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 266 2e-71
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 266 2e-71
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 266 2e-71
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 244 1e-64
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 227 2e-59
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 227 2e-59
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 227 2e-59
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 160 3e-39
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 30 3.2
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 833 bits (2151), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI 60
MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
Sbjct: 1 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI 60
Query: 61 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC 120
FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
Sbjct: 61 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC 120
Query: 121 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK 180
VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
Sbjct: 121 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK 180
Query: 181 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV 240
TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
Sbjct: 181 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV 240
Query: 241 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV 300
VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
Sbjct: 241 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV 300
Query: 301 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE 360
ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
Sbjct: 301 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE 360
Query: 361 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN 420
KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
Sbjct: 361 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN 420
Query: 421 TSES 424
TSES
Sbjct: 421 TSES 424
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 533 bits (1372), Expect = e-151
Identities = 273/385 (70%), Positives = 324/385 (84%), Gaps = 14/385 (3%)
Query: 1 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI 60
ML+RK IIPEEYVL R+A E+ KPR R R +ARF++K G CN+AHKNIREQGRFLQD+
Sbjct: 1 MLSRKGIIPEEYVLTRLA-EDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDV 59
Query: 61 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC 120
FTTLVDLKW HTL+IFTMSFLCSWLLFA+ WWL+AFAHGD+ S + C
Sbjct: 60 FTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDL---------APSEGTAEPC 110
Query: 121 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK 180
VT++ SF+SAFLFSIEVQVTIGFGGRM+TEECPLAI +LI+QNIVGL+INA+MLGCIFMK
Sbjct: 111 VTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMK 170
Query: 181 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV 240
TAQAHRRAETLIFS+HAVIA+R+G+LCFM RVGDLRKSMIISA++ +QVV+KTT+PEGEV
Sbjct: 171 TAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEV 230
Query: 241 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDL-ANQDLEVIVILEGV 299
VP+HQ+DIP++N + N+IFLVAPLII HVID SPLYD++ +DL +QDLE+IVILEGV
Sbjct: 231 VPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGV 290
Query: 300 VETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELD 359
VETTGITTQARTSY+A+EI WG RFV IV EE+G YSVDYSKFGNTVKV P C+AR+LD
Sbjct: 291 VETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLD 350
Query: 360 EKPSILIQTLQKSELSHQNSLRKRN 384
E S L++ L + S + LRKR+
Sbjct: 351 EDHS-LLEALTLA--SARGPLRKRS 372
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 349 bits (895), Expect = 3e-96
Identities = 171/352 (48%), Positives = 244/352 (69%), Gaps = 10/352 (2%)
Query: 14 LARIAAENLRKPRIRDRLPKA--RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRH 71
L + A ++L + RDR + R++ K G CN+ H N+RE R+L DIFTTLVDLKWR
Sbjct: 32 LPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRF 91
Query: 72 TLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAF 131
L+IF M + +WL F ++WWL+A+ GD+ + S T CVTN+ F SAF
Sbjct: 92 NLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSW--------TPCVTNLNGFVSAF 143
Query: 132 LFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETL 191
LFSIE + TIG+G R++T++CP I +L++Q+++G I+NA M+GC+F+K +Q +RAETL
Sbjct: 144 LFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETL 203
Query: 192 IFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVD 251
+FS HAVI++R+GKLC MFRVGDLR S I+ AS+R +++K T EGE +P++Q DI V
Sbjct: 204 VFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVG 263
Query: 252 NPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQART 311
+ +FLV+PLII H I+++SP ++IS L ++LE++VILEG+VE TG+T QAR+
Sbjct: 264 YYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARS 323
Query: 312 SYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDEKPS 363
SYI EI WG+RF ++T E+G Y VDY+ F T + + P SA+EL E S
Sbjct: 324 SYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELAS 375
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 341 bits (874), Expect = 8e-94
Identities = 160/336 (47%), Positives = 233/336 (69%), Gaps = 11/336 (3%)
Query: 25 PRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSW 84
PR R R R++ K G CN+ N+RE R+L D+FTTLVDL+WR +L+ F +++ +W
Sbjct: 16 PRRRGR---QRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTW 72
Query: 85 LLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFG 144
L F +WWL+A+ GD+ ++E + T CV N+ F +AFLFSIE + TIG+G
Sbjct: 73 LFFGAIWWLIAYGRGDL-EHLEDTAW-------TPCVNNLNGFVAAFLFSIETETTIGYG 124
Query: 145 GRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNG 204
R++T++CP I +L+LQ I+G ++NA M+GC+F+K +Q ++RA TL+FS HAV+++R+G
Sbjct: 125 HRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDG 184
Query: 205 KLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAP 264
+LC MFRVGDLR S I+ AS+R ++++ T EGE +P+HQ D+ V + +FLV+P
Sbjct: 185 RLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSP 244
Query: 265 LIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRF 324
L+I H ID SP ++ S L D E++VILEG+VE TG+T QAR+SY+ +E+ WGHRF
Sbjct: 245 LVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRF 304
Query: 325 VSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE 360
S++T E+G Y VDY+ F T +V P CSAREL E
Sbjct: 305 TSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAE 340
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 337 bits (863), Expect = 2e-92
Identities = 160/329 (48%), Positives = 231/329 (70%), Gaps = 8/329 (2%)
Query: 32 PKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
P+ R++ KSG CN+ H N++E R+L D+FTTLVDLKWR L++FTM + +WL F +W
Sbjct: 49 PRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
Query: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
WL+A+ GD+ ++ E CV N+ F SAFLFSIE + TIG+G R++TE+
Sbjct: 109 WLIAYIRGDLDHVGDQ--------EWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK 160
Query: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
CP I +L++Q I+G I+NA M+GC+F+K +Q +RAETL+FS +AVI++R+ KLC MFR
Sbjct: 161 CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFR 220
Query: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
VGDLR S I+ AS+R +++K T EGE +P++Q DI V + +FLV+PLII H I
Sbjct: 221 VGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEI 280
Query: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
+++SP +++S L ++ EV+VILEG+VE TG+T QAR+SY+ E+ WGHRF ++T E
Sbjct: 281 NQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLE 340
Query: 332 EGVYSVDYSKFGNTVKVAAPRCSARELDE 360
+G Y VDY+ F +T + P C A+EL E
Sbjct: 341 KGFYEVDYNTFHDTYETNTPSCCAKELAE 369
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 335 bits (858), Expect = 6e-92
Identities = 168/335 (50%), Positives = 233/335 (69%), Gaps = 12/335 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
++RF+ K G CN+ N+ E+G R+L DIFTT VD++WR LVIF ++F+ SWL F ++
Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
Query: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
WL+A HGD+ A E CV+ V SFT+AFLFSIE Q TIG+G R +T+E
Sbjct: 104 WLIALLHGDLDA----------SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
Query: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
CP+A+ +++ Q+IVG II+A ++G + K A+ +R ETL+FS +AVIA+R+GKLC M+R
Sbjct: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
Query: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
VG+LRKS ++ A VR Q++K T EGE +P+ Q+DI V + IFLV+P+ I H I
Sbjct: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
Query: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
D+ SPLYD+S D+ N D E++VILEG+VE T +TTQ R+SY+A EI WGHR+ ++ EE
Sbjct: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
Query: 332 EGVYSVDYSKFGNTVKVA-APRCSARELDEKPSIL 365
+ Y VDYS+F T +V P CSAR+L EK IL
Sbjct: 334 KHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYIL 368
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 332 bits (852), Expect = 3e-91
Identities = 166/333 (49%), Positives = 233/333 (69%), Gaps = 10/333 (3%)
Query: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
RF+ K+G CN+ N+ E+ R+L D+FTT VD++WR+ L+IF+++FL SWLLF I++W+
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWV 104
Query: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
+A AHGD+ G T CV V F +AFLFSIE Q TIG+G R +TEECP
Sbjct: 105 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECP 156
Query: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
+A+ +++ Q+IVG II++ M+G I K A+ +RA+TL+FS +AV+A+R+GKLC M+RVG
Sbjct: 157 VAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVG 216
Query: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V + IFLV+P+ I H ID+
Sbjct: 217 NLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDE 276
Query: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
SPL+ IS DL D E++VILEG+VE T +TTQAR+SY+A EI WGHRF ++ EE+
Sbjct: 277 ASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN 336
Query: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
Y +DYS F T +V + PRCSA++L E +L
Sbjct: 337 QYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 329 bits (844), Expect = 3e-90
Identities = 162/356 (45%), Positives = 241/356 (67%), Gaps = 14/356 (3%)
Query: 33 KARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
+ RF+ K+G CN+ H N+ E R+L D+FTTLVDLKWR L IF +++ +WL A MW
Sbjct: 43 RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMW 102
Query: 92 WLVAFAHGDIYAYMEKSGMEKSGLES-TVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W++A+ GD+ K+ + + T CV NV +F SAFLF IE + TIG+G R +T+
Sbjct: 103 WVIAYTRGDL---------NKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITD 153
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+CP I + + Q+I+G I++A ++GC+F+K +Q +RAETL+FS HAVI++R+GKL MF
Sbjct: 154 KCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMF 213
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RVG+LR S ++SA +R +++K TPEGE +P+ QL++ V ++ +FLV+PL ICHV
Sbjct: 214 RVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHV 273
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID +SP YD+S + + E++VILEG+VETTG+T QARTSY +E+ WGHRF +++
Sbjct: 274 IDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL 333
Query: 331 EEGVYSVDYSKFGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSM 386
EEG + VDYS+F T +V P S +E +E +L+ + + NS + NS+
Sbjct: 334 EEGFFKVDYSQFHATFEVPTPPYSVKEQEE---MLLMSSPLIAPAITNSKERHNSV 386
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 329 bits (843), Expect = 3e-90
Identities = 165/333 (49%), Positives = 232/333 (69%), Gaps = 10/333 (3%)
Query: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
RF+ K+G CN+A N+ E+ R+L D+FTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 45 RFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
+A AHGD+ G T CV V F +AFLFSIE Q TIG+G R +TEEC
Sbjct: 105 IAVAHGDLEP--------AEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECL 156
Query: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
+A+ +++ Q+IVG II++ M+G I K A+ +RA TL+FS +AV+A+R+GKLC M+RVG
Sbjct: 157 VAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVG 216
Query: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V + IFLV+P+ I H ID+
Sbjct: 217 NLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDE 276
Query: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
SPL+ IS DL D E++VILEG+VE T +TTQAR+SY+A EI WGHRF ++ EE+
Sbjct: 277 ASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN 336
Query: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
Y +DYS F T +V + PRCSA++L E +L
Sbjct: 337 QYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLL 369
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 329 bits (843), Expect = 3e-90
Identities = 167/341 (48%), Positives = 235/341 (68%), Gaps = 10/341 (2%)
Query: 30 RLPKARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
R + RF+ K+G CN+ N+ + R++ DIFTT VD +WR+ L+IF+ +FL SWL F
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 89 IMWWLVAFAHGDIYAY--MEKSGMEKSG------LESTVCVTNVRSFTSAFLFSIEVQVT 140
+++W +AF HGD+ A + +G +G + C+ +V F AFLFS+E Q T
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 141 IGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIA 200
IG+G R +TEECPLA+ +++Q+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 201 VRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIF 260
VR+GKLC M+RVG+LRKS I+ A VR Q++K T EGE +P+ Q D+ V I + IF
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 261 LVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQW 320
LV+P+II H ID+ SPLY + +L ++D E++VILEG+VE T +TTQAR+SY+A EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 321 GHRFVSIVTEEEGVYSVDYSKFGNTVKVA-APRCSARELDE 360
GHRF +V EE+ Y VDYS+F T +VA P CSAREL E
Sbjct: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 329 bits (843), Expect = 3e-90
Identities = 167/341 (48%), Positives = 235/341 (68%), Gaps = 10/341 (2%)
Query: 30 RLPKARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
R + RF+ K+G CN+ N+ + R++ DIFTT VD +WR+ L+IF+ +FL SWL F
Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74
Query: 89 IMWWLVAFAHGDIYAY--MEKSGMEKSG------LESTVCVTNVRSFTSAFLFSIEVQVT 140
+++W +AF HGD+ A + +G +G + C+ +V F AFLFS+E Q T
Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134
Query: 141 IGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIA 200
IG+G R +TEECPLA+ +++Q+IVG +I++ M+G I K A+ +RA+TL+FS HAVI+
Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194
Query: 201 VRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIF 260
VR+GKLC M+RVG+LRKS I+ A VR Q++K T EGE +P+ Q D+ V I + IF
Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254
Query: 261 LVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQW 320
LV+P+II H ID+ SPLY + +L ++D E++VILEG+VE T +TTQAR+SY+A EI W
Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314
Query: 321 GHRFVSIVTEEEGVYSVDYSKFGNTVKVA-APRCSARELDE 360
GHRF +V EE+ Y VDYS+F T +VA P CSAREL E
Sbjct: 315 GHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE 355
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 320 bits (819), Expect = 2e-87
Identities = 161/333 (48%), Positives = 230/333 (69%), Gaps = 11/333 (3%)
Query: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
RF+ K+G CN+ N+ E+ R+L DIFTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
+A AHGD+ G T CV V F +AFLFSI+ Q TI +G R +TEECP
Sbjct: 105 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECP 156
Query: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
+A+ +++ Q+IVG IIN+ M+G I K + +RA+TL+FS +AV+A+R+GKLCFM+RVG
Sbjct: 157 VAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVG 216
Query: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V ++ FLV+P+ I H ID+
Sbjct: 217 NLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDE 276
Query: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
SPL+ IS DL D E+++ILEG+VE T +TTQAR+SY+A EI WGHRF ++ E+
Sbjct: 277 ASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKN 335
Query: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
Y +DY F T +V + PRCSA++L E +L
Sbjct: 336 QYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 368
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 320 bits (819), Expect = 2e-87
Identities = 161/333 (48%), Positives = 230/333 (69%), Gaps = 11/333 (3%)
Query: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
RF+ K+G CN+ N+ E+ R+L DIFTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206
Query: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
+A AHGD+ G T CV V F +AFLFSI+ Q TI +G R +TEECP
Sbjct: 207 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECP 258
Query: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
+A+ +++ Q+IVG IIN+ M+G I K + +RA+TL+FS +AV+A+R+GKLCFM+RVG
Sbjct: 259 VAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVG 318
Query: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V ++ FLV+P+ I H ID+
Sbjct: 319 NLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDE 378
Query: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
SPL+ IS DL D E+++ILEG+VE T +TTQAR+SY+A EI WGHRF ++ E+
Sbjct: 379 ASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKN 437
Query: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
Y +DY F T +V + PRCSA++L E +L
Sbjct: 438 QYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 470
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 320 bits (819), Expect = 2e-87
Identities = 161/333 (48%), Positives = 230/333 (69%), Gaps = 11/333 (3%)
Query: 35 RFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWL 93
RF+ K+G CN+ N+ E+ R+L DIFTT VD++WR+ L+IF+++FL SWLLF +++W+
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 94 VAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECP 153
+A AHGD+ G T CV V F +AFLFSI+ Q TI +G R +TEECP
Sbjct: 105 IAVAHGDLEP--------AEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECP 156
Query: 154 LAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVG 213
+A+ +++ Q+IVG IIN+ M+G I K + +RA+TL+FS +AV+A+R+GKLCFM+RVG
Sbjct: 157 VAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVG 216
Query: 214 DLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDK 273
+LRKS I+ A VR Q++K T EGE +P+ Q+DI V ++ FLV+P+ I H ID+
Sbjct: 217 NLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDE 276
Query: 274 RSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEG 333
SPL+ IS DL D E+++ILEG+VE T +TTQAR+SY+A EI WGHRF ++ E+
Sbjct: 277 ASPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF-EKN 335
Query: 334 VYSVDYSKFGNTVKV-AAPRCSARELDEKPSIL 365
Y +DY F T +V + PRCSA++L E +L
Sbjct: 336 QYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLL 368
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 298 bits (764), Expect = 5e-81
Identities = 148/342 (43%), Positives = 222/342 (64%), Gaps = 12/342 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
+ RF+ K G CN+ N+ QG R+L D+FTT VD++WR ++F+ SFL SWLLF + +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
WL+A HGD+ A + C ++V SF +AFLF++E Q +IG+G R +TEE
Sbjct: 109 WLIASLHGDLAAPPPPAP----------CFSHVASFLAAFLFALETQTSIGYGVRSVTEE 158
Query: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
CP A+ ++LQ I G +++A ++G + K A+ +R ETL+FS +AV+A+R+ +LC M+R
Sbjct: 159 CPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWR 218
Query: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
VG+LR+S ++ A VR Q+++ TPEGE +P+ D+ V ++ IFLV+P+ I H I
Sbjct: 219 VGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEI 278
Query: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
D SPLY++ +LA D E++VILEG+VE T +TTQ R+SY+ E+ WGHRF ++ +
Sbjct: 279 DSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQR 338
Query: 332 EGVYSVDYSKFGNTVKV-AAPRCSARELDEKPSILIQTLQKS 372
Y VDY F T +V P CSA+ELDE+ +L+ S
Sbjct: 339 GSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSS 380
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 298 bits (764), Expect = 5e-81
Identities = 148/342 (43%), Positives = 222/342 (64%), Gaps = 12/342 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
+ RF+ K G CN+ N+ QG R+L D+FTT VD++WR ++F+ SFL SWLLF + +
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
WL+A HGD+ A + C ++V SF +AFLF++E Q +IG+G R +TEE
Sbjct: 109 WLIASLHGDLAAPPPPAP----------CFSHVASFLAAFLFALETQTSIGYGVRSVTEE 158
Query: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
CP A+ ++LQ I G +++A ++G + K A+ +R ETL+FS +AV+A+R+ +LC M+R
Sbjct: 159 CPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWR 218
Query: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
VG+LR+S ++ A VR Q+++ TPEGE +P+ D+ V ++ IFLV+P+ I H I
Sbjct: 219 VGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEI 278
Query: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
D SPLY++ +LA D E++VILEG+VE T +TTQ R+SY+ E+ WGHRF ++ +
Sbjct: 279 DSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQR 338
Query: 332 EGVYSVDYSKFGNTVKV-AAPRCSARELDEKPSILIQTLQKS 372
Y VDY F T +V P CSA+ELDE+ +L+ S
Sbjct: 339 GSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSS 380
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 292 bits (748), Expect = 3e-79
Identities = 145/332 (43%), Positives = 216/332 (65%), Gaps = 10/332 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQGRFL--QDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIM 90
+AR ++K G CN+ N+ Q RF+ DI+TT++DLKWR+ + IF +FL SW F ++
Sbjct: 20 RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLL 79
Query: 91 WWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W+ VA+ H D+ + + T CV N+ TSAFLFS+E QVTIG+G R +TE
Sbjct: 80 WYAVAYIHKDLPEFHPSAN-------HTPCVENINGLTSAFLFSLETQVTIGYGFRCVTE 132
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+C AI +LI Q+I+G+IIN+ M G I K ++ +RA+T+ FS++AVI+ R GKLC +
Sbjct: 133 QCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLI 192
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RV +LRKS++I + + +++K T TPEGE + + Q++I + N+F ++PL I HV
Sbjct: 193 RVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHV 252
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID SP + ++A L QD E++V L+G VE+T T Q RTSY+ EE+ WG+RF IV++
Sbjct: 253 IDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSK 312
Query: 331 -EEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+EG Y VD+ F TV+V P C+ +EK
Sbjct: 313 TKEGKYRVDFHNFSKTVEVETPHCAMCLYNEK 344
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 292 bits (748), Expect = 3e-79
Identities = 145/332 (43%), Positives = 216/332 (65%), Gaps = 10/332 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQGRFL--QDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIM 90
+AR ++K G CN+ N+ Q RF+ DI+TT++DLKWR+ + IF +FL SW F ++
Sbjct: 20 RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLL 79
Query: 91 WWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W+ VA+ H D+ + + T CV N+ TSAFLFS+E QVTIG+G R +TE
Sbjct: 80 WYAVAYIHKDLPEFHPSAN-------HTPCVENINGLTSAFLFSLETQVTIGYGFRCVTE 132
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+C AI +LI Q+I+G+IIN+ M G I K ++ +RA+T+ FS++AVI+ R GKLC +
Sbjct: 133 QCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLI 192
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RV +LRKS++I + + +++K T TPEGE + + Q++I + N+F ++PL I HV
Sbjct: 193 RVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHV 252
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID SP + ++A L QD E++V L+G VE+T T Q RTSY+ EE+ WG+RF IV++
Sbjct: 253 IDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSK 312
Query: 331 -EEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+EG Y VD+ F TV+V P C+ +EK
Sbjct: 313 TKEGKYRVDFHNFSKTVEVETPHCAMCLYNEK 344
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 292 bits (748), Expect = 3e-79
Identities = 145/332 (43%), Positives = 216/332 (65%), Gaps = 10/332 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQGRFL--QDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIM 90
+AR ++K G CN+ N+ Q RF+ DI+TT++DLKWR+ + IF +FL SW F ++
Sbjct: 39 RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLL 98
Query: 91 WWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W+ VA+ H D+ + + T CV N+ TSAFLFS+E QVTIG+G R +TE
Sbjct: 99 WYAVAYIHKDLPEFHPSAN-------HTPCVENINGLTSAFLFSLETQVTIGYGFRCVTE 151
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+C AI +LI Q+I+G+IIN+ M G I K ++ +RA+T+ FS++AVI+ R GKLC +
Sbjct: 152 QCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLI 211
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RV +LRKS++I + + +++K T TPEGE + + Q++I + N+F ++PL I HV
Sbjct: 212 RVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHV 271
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID SP + ++A L QD E++V L+G VE+T T Q RTSY+ EE+ WG+RF IV++
Sbjct: 272 IDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSK 331
Query: 331 -EEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+EG Y VD+ F TV+V P C+ +EK
Sbjct: 332 TKEGKYRVDFHNFSKTVEVETPHCAMCLYNEK 363
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 292 bits (748), Expect = 3e-79
Identities = 145/332 (43%), Positives = 216/332 (65%), Gaps = 10/332 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQGRFL--QDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIM 90
+AR ++K G CN+ N+ Q RF+ DI+TT++DLKWR+ + IF +FL SW F ++
Sbjct: 20 RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLL 79
Query: 91 WWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W+ VA+ H D+ + + T CV N+ TSAFLFS+E QVTIG+G R +TE
Sbjct: 80 WYAVAYIHKDLPEFHPSAN-------HTPCVENINGLTSAFLFSLETQVTIGYGFRCVTE 132
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+C AI +LI Q+I+G+IIN+ M G I K ++ +RA+T+ FS++AVI+ R GKLC +
Sbjct: 133 QCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLI 192
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RV +LRKS++I + + +++K T TPEGE + + Q++I + N+F ++PL I HV
Sbjct: 193 RVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHV 252
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID SP + ++A L QD E++V L+G VE+T T Q RTSY+ EE+ WG+RF IV++
Sbjct: 253 IDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSK 312
Query: 331 -EEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+EG Y VD+ F TV+V P C+ +EK
Sbjct: 313 TKEGKYRVDFHNFSKTVEVETPHCAMCLYNEK 344
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 292 bits (748), Expect = 3e-79
Identities = 145/332 (43%), Positives = 216/332 (65%), Gaps = 10/332 (3%)
Query: 33 KARFIAKSGACNLAHKNIREQGRFL--QDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIM 90
+AR ++K G CN+ N+ Q RF+ DI+TT++DLKWR+ + IF +FL SW F ++
Sbjct: 20 RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLL 79
Query: 91 WWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150
W+ VA+ H D+ + + T CV N+ TSAFLFS+E QVTIG+G R +TE
Sbjct: 80 WYAVAYIHKDLPEFHPSAN-------HTPCVENINGLTSAFLFSLETQVTIGYGFRCVTE 132
Query: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210
+C AI +LI Q+I+G+IIN+ M G I K ++ +RA+T+ FS++AVI+ R GKLC +
Sbjct: 133 QCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLI 192
Query: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270
RV +LRKS++I + + +++K T TPEGE + + Q++I + N+F ++PL I HV
Sbjct: 193 RVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHV 252
Query: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330
ID SP + ++A L QD E++V L+G VE+T T Q RTSY+ EE+ WG+RF IV++
Sbjct: 253 IDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSK 312
Query: 331 -EEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+EG Y VD+ F TV+V P C+ +EK
Sbjct: 313 TKEGKYRVDFHNFSKTVEVETPHCAMCLYNEK 344
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 266 bits (681), Expect = 2e-71
Identities = 138/333 (41%), Positives = 208/333 (62%), Gaps = 16/333 (4%)
Query: 30 RLPKARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
R + R + K G+CN+ K+I E G ++ DIFTTLVD KWRH VIF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 89 IMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMM 148
++WL+AF HGD+ + + T CV NV SFT AFLFS+E Q TIG+G R +
Sbjct: 90 SVFWLIAFHHGDLL----------NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCV 139
Query: 149 TEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCF 208
TEEC +A+ ++ILQ+I+ IIN ++G K A A +RA+T+ FS A+I +R+GKLC
Sbjct: 140 TEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCL 199
Query: 209 MFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIIC 268
M+R+GD R + ++ +VR Q+++ T EG + + D + ++ I LV P+ I
Sbjct: 200 MWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFK-----DLKLVNDQIILVTPVTIV 254
Query: 269 HVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIV 328
H ID SPLY + +A + E++V ++TG + Q+R+SY+ EI WGHRF ++
Sbjct: 255 HEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL 314
Query: 329 TEEEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+ Y V+ +F +V+V AP CSA++LD K
Sbjct: 315 EVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWK 347
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 266 bits (681), Expect = 2e-71
Identities = 138/333 (41%), Positives = 208/333 (62%), Gaps = 16/333 (4%)
Query: 30 RLPKARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
R + R + K G+CN+ K+I E G ++ DIFTTLVD KWRH VIF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 89 IMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMM 148
++WL+AF HGD+ + + T CV NV SFT AFLFS+E Q TIG+G R +
Sbjct: 90 SVFWLIAFHHGDLL----------NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCV 139
Query: 149 TEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCF 208
TEEC +A+ ++ILQ+I+ IIN ++G K A A +RA+T+ FS A+I +R+GKLC
Sbjct: 140 TEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCL 199
Query: 209 MFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIIC 268
M+R+GD R + ++ +VR Q+++ T EG + + D + ++ I LV P+ I
Sbjct: 200 MWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFK-----DLKLVNDQIILVTPVTIV 254
Query: 269 HVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIV 328
H ID SPLY + +A + E++V ++TG + Q+R+SY+ EI WGHRF ++
Sbjct: 255 HEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL 314
Query: 329 TEEEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+ Y V+ +F +V+V AP CSA++LD K
Sbjct: 315 EVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWK 347
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 266 bits (681), Expect = 2e-71
Identities = 138/333 (41%), Positives = 208/333 (62%), Gaps = 16/333 (4%)
Query: 30 RLPKARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFA 88
R + R + K G+CN+ K+I E G ++ DIFTTLVD KWRH VIF++S++ SWL+F
Sbjct: 30 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFG 89
Query: 89 IMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMM 148
++WL+AF HGD+ + + T CV NV SFT AFLFS+E Q TIG+G R +
Sbjct: 90 SVFWLIAFHHGDLL----------NDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCV 139
Query: 149 TEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCF 208
TEEC +A+ ++ILQ+I+ IIN ++G K A A +RA+T+ FS A+I +R+GKLC
Sbjct: 140 TEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCL 199
Query: 209 MFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIIC 268
M+R+GD R + ++ +VR Q+++ T EG + + D + ++ I LV P+ I
Sbjct: 200 MWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFK-----DLKLVNDQIILVTPVTIV 254
Query: 269 HVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIV 328
H ID SPLY + +A + E++V ++TG + Q+R+SY+ EI WGHRF ++
Sbjct: 255 HEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL 314
Query: 329 TEEEGVYSVDYSKFGNTVKVAAPRCSARELDEK 361
+ Y V+ +F +V+V AP CSA++LD K
Sbjct: 315 EVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWK 347
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 244 bits (623), Expect = 1e-64
Identities = 128/330 (38%), Positives = 200/330 (60%), Gaps = 10/330 (3%)
Query: 24 KPRIRDRLPKARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLC 82
+P + + + R + K G N+ ++I ++ +L+D++TT +D++WR+ L++F+ +F
Sbjct: 18 RPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAG 77
Query: 83 SWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIG 142
+W LF ++W+LVA AHGD+ + T CV V + T AFLFS+E Q TIG
Sbjct: 78 TWFLFGVVWYLVAVAHGDLLELDPPAN-------HTPCVVQVHTLTGAFLFSLESQTTIG 130
Query: 143 FGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVR 202
+G R ++EECPLAI +LI Q ++ I+ + G K A+ +RAET+ FS+HAV+A
Sbjct: 131 YGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASH 190
Query: 203 NGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLV 262
NGK C M RV ++RKS++I V ++++ T EGE + ++Q+++ S++ FL+
Sbjct: 191 NGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLI 250
Query: 263 APLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGH 322
PL HV+D+ SPL D+ D E+++IL G VE+T T Q RTSY+ EEI WG+
Sbjct: 251 LPLTFYHVVDETSPLKDLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGY 309
Query: 323 RFV-SIVTEEEGVYSVDYSKFGNTVKVAAP 351
F +I G Y D+S F VKVA+P
Sbjct: 310 EFTPAISLSASGKYIADFSLFDQVVKVASP 339
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 227 bits (578), Expect = 2e-59
Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%)
Query: 33 KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86
+ R ++KSG H N+R +LQD++TT++D+KWR+ L +F +F+ +W L
Sbjct: 26 RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80
Query: 87 FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146
F ++++ +AF HGD+ + G S T C+ V S T AFLFS+E Q TIG+G R
Sbjct: 81 FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133
Query: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206
+TEECP AI +L+ Q ++ +I + G K A+ +RAET+ FS AVI +NGKL
Sbjct: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193
Query: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266
C + +V ++RKS++I + ++++ T EGE + ++Q + S + FL+ P+
Sbjct: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253
Query: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326
HV+D+ SPL D++ +L ++ E++V+L VE+T Q+RTSYI EEI WG FV
Sbjct: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313
Query: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354
+V+ + G Y D+S+F K +P C+
Sbjct: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 227 bits (578), Expect = 2e-59
Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%)
Query: 33 KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86
+ R ++KSG H N+R +LQD++TT++D+KWR+ L +F +F+ +W L
Sbjct: 26 RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80
Query: 87 FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146
F ++++ +AF HGD+ + G S T C+ V S T AFLFS+E Q TIG+G R
Sbjct: 81 FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133
Query: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206
+TEECP AI +L+ Q ++ +I + G K A+ +RAET+ FS AVI +NGKL
Sbjct: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193
Query: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266
C + +V ++RKS++I + ++++ T EGE + ++Q + S + FL+ P+
Sbjct: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253
Query: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326
HV+D+ SPL D++ +L ++ E++V+L VE+T Q+RTSYI EEI WG FV
Sbjct: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313
Query: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354
+V+ + G Y D+S+F K +P C+
Sbjct: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 227 bits (578), Expect = 2e-59
Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%)
Query: 33 KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86
+ R ++KSG H N+R +LQD++TT++D+KWR+ L +F +F+ +W L
Sbjct: 26 RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80
Query: 87 FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146
F ++++ +AF HGD+ + G S T C+ V S T AFLFS+E Q TIG+G R
Sbjct: 81 FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133
Query: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206
+TEECP AI +L+ Q ++ +I + G K A+ +RAET+ FS AVI +NGKL
Sbjct: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193
Query: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266
C + +V ++RKS++I + ++++ T EGE + ++Q + S + FL+ P+
Sbjct: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253
Query: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326
HV+D+ SPL D++ +L ++ E++V+L VE+T Q+RTSYI EEI WG FV
Sbjct: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313
Query: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354
+V+ + G Y D+S+F K +P C+
Sbjct: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 160 bits (404), Expect = 3e-39
Identities = 101/316 (31%), Positives = 166/316 (52%), Gaps = 16/316 (5%)
Query: 35 RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLV 94
R + K G L + +L+D + L+D++WR +++F+ SF+ WL+FA++W+++
Sbjct: 19 RMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYVL 78
Query: 95 AFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPL 154
A +GD+ + + T+CV + SFT+AF FS+E Q+TIG+G + +CP
Sbjct: 79 AEMNGDL-----ELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
Query: 155 AITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGD 214
AI +L +Q ++GL++ A + G K A+ RA ++ F+ AV+A +GK +F+V +
Sbjct: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
Query: 215 LRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKR 274
R S + SVR+ V G++ +D +D F + PL H I
Sbjct: 194 TRPSPL--TSVRVSAVLYQERENGKLYQT-SVDFHLDGISSDECPFFIFPLTYYHSITPS 250
Query: 275 SPLYDISATDLANQD---LEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE- 330
SPL AT L +++ E++V L + E TG Q RTSY+ EI H F S++T
Sbjct: 251 SPL----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRG 306
Query: 331 EEGVYSVDYSKFGNTV 346
+G Y + F TV
Sbjct: 307 SKGEYQIKMENFDKTV 322
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 30.4 bits (67), Expect = 3.2
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 330 EEEGVYSVDYSKFGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQ-----NSLRKRN 384
+EE + VD T ++ R A++L+E+ I + Q +SH+ N L RN
Sbjct: 410 KEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARN 469
Query: 385 SMRRNNSMRRNNSIRR 400
+ R N +R+ N+ R
Sbjct: 470 AERNLNDLRKENAHNR 485
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,556,029
Number of Sequences: 37866
Number of extensions: 532673
Number of successful extensions: 1917
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1809
Number of HSP's gapped (non-prelim): 41
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.