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Search of human proteins with 4758862
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758862 eukaryotic translation elongation factor 1 epsilon 1
isoform 1 [Homo sapiens]
(174 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758862 eukaryotic translation elongation factor 1 epsilon 1 ... 350 3e-97
gi|208879470 eukaryotic translation elongation factor 1 epsilon ... 255 2e-68
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens] 47 1e-05
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom... 40 8e-04
gi|154707916 glutathione S-transferase, C-terminal domain contai... 38 0.004
gi|149588660 glutathione S-transferase, C-terminal domain contai... 38 0.004
gi|5454158 valyl-tRNA synthetase [Homo sapiens] 34 0.073
gi|11136628 eukaryotic translation elongation factor 1 beta 2 [H... 32 0.36
gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Ho... 32 0.36
gi|83376130 eukaryotic translation elongation factor 1 beta 2 [H... 32 0.36
gi|11125770 aminoacyl tRNA synthetase complex-interacting multif... 31 0.62
gi|14043022 methionyl-tRNA synthetase [Homo sapiens] 30 1.1
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens] 30 1.1
gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens] 29 1.8
gi|239751568 PREDICTED: hypothetical protein [Homo sapiens] 28 3.1
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 28 3.1
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 28 5.2
gi|24432083 UDP glycosyltransferase 3 family, polypeptide A1 [Ho... 28 5.2
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 28 5.2
gi|169215618 PREDICTED: similar to Glutathione S-transferase the... 27 8.9
gi|148886661 exportin 4 [Homo sapiens] 27 8.9
>gi|4758862 eukaryotic translation elongation factor 1 epsilon 1
isoform 1 [Homo sapiens]
Length = 174
Score = 350 bits (899), Expect = 3e-97
Identities = 174/174 (100%), Positives = 174/174 (100%)
Query: 1 MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL
Sbjct: 1 MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
Query: 61 LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL
Sbjct: 61 LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
Query: 121 YYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH 174
YYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH
Sbjct: 121 YYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH 174
>gi|208879470 eukaryotic translation elongation factor 1 epsilon 1
isoform 2 [Homo sapiens]
Length = 139
Score = 255 bits (651), Expect = 2e-68
Identities = 128/129 (99%), Positives = 129/129 (100%)
Query: 1 MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL
Sbjct: 1 MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
Query: 61 LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL
Sbjct: 61 LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
Query: 121 YYGLHRFIV 129
YYGLHRFI+
Sbjct: 121 YYGLHRFII 129
>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
Length = 1512
Score = 46.6 bits (109), Expect = 1e-05
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 32 VLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDI 91
+L + T + +I +L + A L GS E + WLE+ T++ SS +
Sbjct: 39 ILHVSENVIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKL---SSCDSF 95
Query: 92 HTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLH-RFIVDLTVQEKEKYLNVSRWF 146
+ + +LN L + YL G + +LAD+ ++ L +++K+ ++V RWF
Sbjct: 96 TSTINELNHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWF 151
>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
sapiens]
Length = 437
Score = 40.4 bits (93), Expect = 8e-04
Identities = 36/157 (22%), Positives = 70/157 (44%), Gaps = 29/157 (18%)
Query: 29 QIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSS- 87
++P + ++G + IA ++ + E L GST E A V QW+ + + + +S
Sbjct: 57 KVPAFEGDDGFCVFESNAIAYYV----SNEELRGSTPEAAAQVVQWVSFADSDIVPPAST 112
Query: 88 -------------------KNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL---YYGLH 125
K ++ +L L++YL+ + +L G TLADI + L+
Sbjct: 113 WVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLY 172
Query: 126 RFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSV 162
+ +++ + ++ + N +RWF + P R L V
Sbjct: 173 KQVLEPSF--RQAFPNTNRWFLTCINQPQFRAVLGEV 207
>gi|154707916 glutathione S-transferase, C-terminal domain
containing isoform 2 [Homo sapiens]
Length = 546
Score = 38.1 bits (87), Expect = 0.004
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 104 DKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLN---VSRWFCHIQHYPGIR 156
+ V+ G FTLADI+L +H F+V ++ + EK + ++ W+ IQ PG++
Sbjct: 187 EHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVK 242
>gi|149588660 glutathione S-transferase, C-terminal domain
containing isoform 1 [Homo sapiens]
Length = 633
Score = 38.1 bits (87), Expect = 0.004
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 104 DKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLN---VSRWFCHIQHYPGIR 156
+ V+ G FTLADI+L +H F+V ++ + EK + ++ W+ IQ PG++
Sbjct: 274 EHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVK 329
>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
Length = 1264
Score = 33.9 bits (76), Expect = 0.073
Identities = 40/157 (25%), Positives = 58/157 (36%), Gaps = 26/157 (16%)
Query: 29 QIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQV------ 82
++P L+ G T A L+ A GS A +VQQW+ Y T++
Sbjct: 56 RLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAA--VLVQQWVSYADTELIPAACG 113
Query: 83 -------------DGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGL---HR 126
D + + L L +L YL G TLAD+ L R
Sbjct: 114 ATLPALGLRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFR 173
Query: 127 FIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVV 163
+++D + + NV+RWF P R L VV
Sbjct: 174 YVLDPPA--RRIWNNVTRWFVTCVRQPEFRAVLGEVV 208
>gi|11136628 eukaryotic translation elongation factor 1 beta 2 [Homo
sapiens]
Length = 225
Score = 31.6 bits (70), Expect = 0.36
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 95 LKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHY-- 152
L+ LN YL DK Y+ GY + AD+ ++ ++ + RW+ HI+ Y
Sbjct: 12 LQVLNDYLADKSYIEGYVPSQADVAVFEA-------VSSPPPADLCHALRWYNHIKSYEK 64
Query: 153 -----PGIRQHL 159
PG+++ L
Sbjct: 65 EKASLPGVKKAL 76
>gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Homo
sapiens]
Length = 225
Score = 31.6 bits (70), Expect = 0.36
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 95 LKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHY-- 152
L+ LN YL DK Y+ GY + AD+ ++ ++ + RW+ HI+ Y
Sbjct: 12 LQVLNDYLADKSYIEGYVPSQADVAVFEA-------VSSPPPADLCHALRWYNHIKSYEK 64
Query: 153 -----PGIRQHL 159
PG+++ L
Sbjct: 65 EKASLPGVKKAL 76
>gi|83376130 eukaryotic translation elongation factor 1 beta 2 [Homo
sapiens]
Length = 225
Score = 31.6 bits (70), Expect = 0.36
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 95 LKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHY-- 152
L+ LN YL DK Y+ GY + AD+ ++ ++ + RW+ HI+ Y
Sbjct: 12 LQVLNDYLADKSYIEGYVPSQADVAVFEA-------VSSPPPADLCHALRWYNHIKSYEK 64
Query: 153 -----PGIRQHL 159
PG+++ L
Sbjct: 65 EKASLPGVKKAL 76
>gi|11125770 aminoacyl tRNA synthetase complex-interacting
multifunctional protein 2 [Homo sapiens]
Length = 320
Score = 30.8 bits (68), Expect = 0.62
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 7/82 (8%)
Query: 65 AEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGL 124
A ++ W++ + Q+ SSK + + +NS L +L G T+AD++L+ L
Sbjct: 227 AVNATLIDSWVDIAIFQLKEGSSKEKA-AVFRSMNSALGKSPWLAGNELTVADVVLWSVL 285
Query: 125 HRF-IVDLTVQEKEKYLNVSRW 145
+ +TV NV RW
Sbjct: 286 QQIGGCSVTVP-----ANVQRW 302
>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
Length = 900
Score = 30.0 bits (66), Expect = 1.1
Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 26/120 (21%)
Query: 29 QIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVD----- 83
++PVLQ ++G L + I + + L S E+ + QWLE+ T++
Sbjct: 47 KVPVLQLDSGNYLFSTSAICRY--------FFLLSGWEQDDLTNQWLEWEATELQPALSA 98
Query: 84 -----------GHSSKNDIHTLLKDLNSYL--EDKVYLTGYNFTLADILLYYGLHRFIVD 130
G + L ++ L ++ +L G +LADI+L+ L+ + D
Sbjct: 99 ALYYLVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQD 158
>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 30.0 bits (66), Expect = 1.1
Identities = 13/32 (40%), Positives = 16/32 (50%)
Query: 121 YYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHY 152
Y G H IV V ++E Y NV +W I Y
Sbjct: 78 YRGAHGIIVVYDVTDQESYANVKQWLQEIDRY 109
>gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens]
Length = 831
Score = 29.3 bits (64), Expect = 1.8
Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 98 LNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQ 150
LN +L + Y+ GY+ + AD+ + L D + +V+RWF HI+
Sbjct: 28 LNEHLSTRSYVQGYSLSQADVDAFRQLSAPPAD------PQLFHVARWFRHIE 74
>gi|239751568 PREDICTED: hypothetical protein [Homo sapiens]
Length = 307
Score = 28.5 bits (62), Expect = 3.1
Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 106 VYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRW---FCHIQHYPGIRQHLSSV 162
VY+ Y + I +Y H +I T Y+ + + + HI Y G+R + +
Sbjct: 71 VYIHLYTYVCIYICIYVYTHMYIYRCTYMYIHIYVYIQVYVYVYTHICIYTGVRIRIYTY 130
Query: 163 VFIKNRLYTNSH 174
++I YT H
Sbjct: 131 MYIYRCTYTYIH 142
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 28.5 bits (62), Expect = 3.1
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 32 VLQTNNGPSLTGLTTIAAHLVKQANKE--YLLGSTAEEKAIVQQWLE-YRVTQVDGHSSK 88
V +T++G +T + + L + K Y+LG+ + + + E R T+V G +K
Sbjct: 251 VRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAK 310
Query: 89 NDIHTLLKDLNSYLEDK 105
++ L++ L + LE+K
Sbjct: 311 EEVSQLVRGLGAVLEEK 327
>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
sapiens]
Length = 205
Score = 27.7 bits (60), Expect = 5.2
Identities = 12/32 (37%), Positives = 16/32 (50%)
Query: 121 YYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHY 152
Y G H IV V ++E + NV +W I Y
Sbjct: 81 YRGAHGIIVVYDVTDQESFNNVKQWLQEIDRY 112
>gi|24432083 UDP glycosyltransferase 3 family, polypeptide A1 [Homo
sapiens]
Length = 523
Score = 27.7 bits (60), Expect = 5.2
Identities = 11/31 (35%), Positives = 17/31 (54%)
Query: 133 VQEKEKYLNVSRWFCHIQHYPGIRQHLSSVV 163
++E+EK V RWF H I++H S +
Sbjct: 67 IKEEEKSYQVIRWFSPEDHQKRIKKHFDSYI 97
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 27.7 bits (60), Expect = 5.2
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 33 LQTNNGPSLTGLTTIAAHLVKQ-ANKEYLLGSTAEEKAIVQQWLEYRVTQVDG 84
L TN P+ TGL T+ L Q ++ Y L EE+A +Q + R + G
Sbjct: 56 LDTNQAPNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALG 108
>gi|169215618 PREDICTED: similar to Glutathione S-transferase
theta-4 [Homo sapiens]
Length = 176
Score = 26.9 bits (58), Expect = 8.9
Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 9/55 (16%)
Query: 74 WLEYRVTQVDGH--SSKNDIHTLLKDLNS-------YLEDKVYLTGYNFTLADIL 119
WL+ + ++ G S++ H + + NS +L+DK+++TG +LAD++
Sbjct: 50 WLKLLIPKITGEEVSAEKMEHAVEEVKNSLQLFEEKFLQDKMFITGNQISLADLV 104
>gi|148886661 exportin 4 [Homo sapiens]
Length = 1151
Score = 26.9 bits (58), Expect = 8.9
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 6/70 (8%)
Query: 59 YLLG--STAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLA 116
YLL + E I + +EY + HSS+ DI+T L+ L S E + GYN T +
Sbjct: 548 YLLADDTQGETPLIPPEIMEYSIK----HSSEVDINTTLQILGSPGEKASSIPGYNRTDS 603
Query: 117 DILLYYGLHR 126
I L + R
Sbjct: 604 VIRLLSAILR 613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,099,455
Number of Sequences: 37866
Number of extensions: 242908
Number of successful extensions: 536
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 522
Number of HSP's gapped (non-prelim): 22
length of query: 174
length of database: 18,247,518
effective HSP length: 95
effective length of query: 79
effective length of database: 14,650,248
effective search space: 1157369592
effective search space used: 1157369592
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.