Guide to the Human Genome
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Search of human proteins with 46409468

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46409468 hypothetical protein LOC392490 [Homo sapiens]
         (140 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46409468 hypothetical protein LOC392490 [Homo sapiens]             282   7e-77
gi|4507669 tumor protein, translationally-controlled 1 [Homo sap...   232   9e-62
gi|169178083 PREDICTED: similar to tumor protein, translationall...   176   4e-45
gi|169179309 PREDICTED: similar to tumor protein, translationall...   176   4e-45
gi|169181065 PREDICTED: similar to tumor protein, translationall...   174   2e-44
gi|117414135 apoptosis inhibitor [Homo sapiens]                       135   1e-32
gi|239757896 PREDICTED: similar to hCG1793821 [Homo sapiens]          108   1e-24
gi|239752409 PREDICTED: similar to hCG1793821 [Homo sapiens]          108   1e-24
gi|239746926 PREDICTED: similar to hCG1793821 [Homo sapiens]          106   5e-24
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]    32   0.22 
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]     32   0.22 
gi|41352705 kinesin family member 3C [Homo sapiens]                    29   1.4  
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom...    28   1.9  
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom...    28   1.9  
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    28   1.9  
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept...    28   3.2  
gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1 precu...    26   9.3  
gi|21071077 dishevelled-associated activator of morphogenesis 1 ...    26   9.3  
gi|13376460 zinc finger protein 556 [Homo sapiens]                     26   9.3  

>gi|46409468 hypothetical protein LOC392490 [Homo sapiens]
          Length = 140

 Score =  282 bits (721), Expect = 7e-77
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   METVIMITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAE 60
           METVIMITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAE
Sbjct: 1   METVIMITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAE 60

Query: 61  GPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFM 120
           GPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFM
Sbjct: 61  GPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFM 120

Query: 121 TGAAEQIKHILANFKNYQKT 140
           TGAAEQIKHILANFKNYQKT
Sbjct: 121 TGAAEQIKHILANFKNYQKT 140


>gi|4507669 tumor protein, translationally-controlled 1 [Homo
           sapiens]
          Length = 172

 Score =  232 bits (591), Expect = 9e-62
 Identities = 118/133 (88%), Positives = 122/133 (91%)

Query: 6   MITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGK 65
           MI Y DLISH EMFSD Y  +EIADGL LEVEGK+VSRTEGNI DSLIGGNASAEGPEG+
Sbjct: 1   MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGE 60

Query: 66  GTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAE 125
           GTESTVITGVD VMNHHLQETSFTKEAY K IKDYMKSIKGKLEEQRP+RVKPFMTGAAE
Sbjct: 61  GTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAE 120

Query: 126 QIKHILANFKNYQ 138
           QIKHILANFKNYQ
Sbjct: 121 QIKHILANFKNYQ 133


>gi|169178083 PREDICTED: similar to tumor protein,
           translationally-controlled 1 [Homo sapiens]
          Length = 138

 Score =  176 bits (447), Expect = 4e-45
 Identities = 88/99 (88%), Positives = 92/99 (92%)

Query: 40  IVSRTEGNIFDSLIGGNASAEGPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKD 99
           +VSRTEGNI DSLIGGN SAEGPEG+GTESTVIT VD VMNHHLQETSFTKEA+ K IKD
Sbjct: 1   MVSRTEGNIDDSLIGGNVSAEGPEGEGTESTVITAVDVVMNHHLQETSFTKEAHKKYIKD 60

Query: 100 YMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNYQ 138
           YMKSIKGKLEE RP+RVKPFMTGAAEQIKHILANFKNYQ
Sbjct: 61  YMKSIKGKLEELRPERVKPFMTGAAEQIKHILANFKNYQ 99


>gi|169179309 PREDICTED: similar to tumor protein,
           translationally-controlled 1 [Homo sapiens]
          Length = 138

 Score =  176 bits (447), Expect = 4e-45
 Identities = 88/99 (88%), Positives = 92/99 (92%)

Query: 40  IVSRTEGNIFDSLIGGNASAEGPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKD 99
           +VSRTEGNI DSLIGGN SAEGPEG+GTESTVIT VD VMNHHLQETSFTKEA+ K IKD
Sbjct: 1   MVSRTEGNIDDSLIGGNVSAEGPEGEGTESTVITAVDVVMNHHLQETSFTKEAHKKYIKD 60

Query: 100 YMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNYQ 138
           YMKSIKGKLEE RP+RVKPFMTGAAEQIKHILANFKNYQ
Sbjct: 61  YMKSIKGKLEELRPERVKPFMTGAAEQIKHILANFKNYQ 99


>gi|169181065 PREDICTED: similar to tumor protein,
           translationally-controlled 1 [Homo sapiens]
          Length = 138

 Score =  174 bits (442), Expect = 2e-44
 Identities = 87/98 (88%), Positives = 91/98 (92%)

Query: 40  IVSRTEGNIFDSLIGGNASAEGPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKD 99
           +VSRTEGNI DSLIGGN SAEGPEG+GTESTVIT VD VMNHHLQETSFTKEA+ K IKD
Sbjct: 1   MVSRTEGNIDDSLIGGNVSAEGPEGEGTESTVITAVDVVMNHHLQETSFTKEAHKKYIKD 60

Query: 100 YMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNY 137
           YMKSIKGKLEE RP+RVKPFMTGAAEQIKHILANFKNY
Sbjct: 61  YMKSIKGKLEELRPERVKPFMTGAAEQIKHILANFKNY 98


>gi|117414135 apoptosis inhibitor [Homo sapiens]
          Length = 127

 Score =  135 bits (339), Expect = 1e-32
 Identities = 73/118 (61%), Positives = 85/118 (72%)

Query: 18  MFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGKGTESTVITGVDS 77
           MFSD Y   EI +GL LEVE K++S+T GN  DSLIG N+S+E  E + TEST+IT VD 
Sbjct: 1   MFSDIYKIWEITNGLCLEVEQKMLSKTTGNTDDSLIGRNSSSESTEDEVTESTIITSVDI 60

Query: 78  VMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFK 135
           V NHHLQE+ FTKEAY K IKDYMKSI  KLEEQRP+RVK F+TG   +    L  FK
Sbjct: 61  VTNHHLQESIFTKEAYKKYIKDYMKSINEKLEEQRPERVKLFITGMKNKSSTSLLIFK 118


>gi|239757896 PREDICTED: similar to hCG1793821 [Homo sapiens]
          Length = 131

 Score =  108 bits (270), Expect = 1e-24
 Identities = 63/91 (69%), Positives = 70/91 (76%), Gaps = 5/91 (5%)

Query: 6  MITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGK 65
          MI Y DLISHSE+    Y +QEI  G  LEVEGKIVSRTE NI  SLIG NAS E PEG+
Sbjct: 1  MIIYPDLISHSEI----YKNQEITKGPCLEVEGKIVSRTEDNIDGSLIGRNASTEVPEGE 56

Query: 66 GTESTVITGVDSVMNHHLQETSFTKEAYNKC 96
           T+STVITGVD VM++HLQETSFTKEA + C
Sbjct: 57 ETQSTVITGVD-VMHYHLQETSFTKEASHPC 86


>gi|239752409 PREDICTED: similar to hCG1793821 [Homo sapiens]
          Length = 131

 Score =  108 bits (270), Expect = 1e-24
 Identities = 63/91 (69%), Positives = 70/91 (76%), Gaps = 5/91 (5%)

Query: 6  MITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGK 65
          MI Y DLISHSE+    Y +QEI  G  LEVEGKIVSRTE NI  SLIG NAS E PEG+
Sbjct: 1  MIIYPDLISHSEI----YKNQEITKGPCLEVEGKIVSRTEDNIDGSLIGRNASTEVPEGE 56

Query: 66 GTESTVITGVDSVMNHHLQETSFTKEAYNKC 96
           T+STVITGVD VM++HLQETSFTKEA + C
Sbjct: 57 ETQSTVITGVD-VMHYHLQETSFTKEASHPC 86


>gi|239746926 PREDICTED: similar to hCG1793821 [Homo sapiens]
          Length = 131

 Score =  106 bits (265), Expect = 5e-24
 Identities = 62/91 (68%), Positives = 69/91 (75%), Gaps = 5/91 (5%)

Query: 6  MITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGK 65
          MI Y DLISHSE+    Y +QEI  G  LEVEGKIVSRTE N   SLIG NAS E PEG+
Sbjct: 1  MIIYPDLISHSEI----YKNQEITKGPCLEVEGKIVSRTEDNTDGSLIGRNASTEVPEGE 56

Query: 66 GTESTVITGVDSVMNHHLQETSFTKEAYNKC 96
           T+STVITGVD VM++HLQETSFTKEA + C
Sbjct: 57 ETQSTVITGVD-VMHYHLQETSFTKEASHPC 86


>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
          Length = 1068

 Score = 31.6 bits (70), Expect = 0.22
 Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 2/61 (3%)

Query: 78  VMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNY 137
           ++   L++     + Y   +K  + +++G+LEEQR ++ K  +    EQ++H LA  +  
Sbjct: 365 MLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDN--EQLRHELAQLRAA 422

Query: 138 Q 138
           Q
Sbjct: 423 Q 423


>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
          Length = 1048

 Score = 31.6 bits (70), Expect = 0.22
 Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 2/61 (3%)

Query: 78  VMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNY 137
           ++   L++     + Y   +K  + +++G+LEEQR ++ K  +    EQ++H LA  +  
Sbjct: 345 MLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDN--EQLRHELAQLRAA 402

Query: 138 Q 138
           Q
Sbjct: 403 Q 403


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score = 28.9 bits (63), Expect = 1.4
 Identities = 15/51 (29%), Positives = 26/51 (50%)

Query: 62  PEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQR 112
           PEG   E+ V    D   N+H       + A  K +++Y++  K +LEE++
Sbjct: 422 PEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEK 472


>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
           sapiens]
          Length = 381

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 68  ESTVITGVDSVMNHHLQETSF------------TKEAYNKCIKDYMKSIKGKLEEQRPKR 115
           E+  +TGVD  M   ++E S              K A  +  + Y  S+  K+EE+  K+
Sbjct: 84  ETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKK 143

Query: 116 VKPFMTGAAEQIKHILANFKNYQK 139
           ++        +    L  +K YQ+
Sbjct: 144 IEDMKENERIKATKALEAWKEYQR 167


>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
           sapiens]
          Length = 376

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 68  ESTVITGVDSVMNHHLQETSF------------TKEAYNKCIKDYMKSIKGKLEEQRPKR 115
           E+  +TGVD  M   ++E S              K A  +  + Y  S+  K+EE+  K+
Sbjct: 84  ETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKK 143

Query: 116 VKPFMTGAAEQIKHILANFKNYQK 139
           ++        +    L  +K YQ+
Sbjct: 144 IEDMKENERIKATKALEAWKEYQR 167


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 68  ESTVITGVDSVMNHHLQETSF------------TKEAYNKCIKDYMKSIKGKLEEQRPKR 115
           E+  +TGVD  M   ++E S              K A  +  + Y  S+  K+EE+  K+
Sbjct: 84  ETLSVTGVDKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKK 143

Query: 116 VKPFMTGAAEQIKHILANFKNYQK 139
           ++        +    L  +K YQ+
Sbjct: 144 IEDMKENERIKATKALEAWKEYQR 167


>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
           [Homo sapiens]
          Length = 1102

 Score = 27.7 bits (60), Expect = 3.2
 Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 10/72 (13%)

Query: 76  DSVMNHHLQETSFTKEAYNKCIKDYMKSIKG--------KLEEQRPKRVKPFMTGAAEQI 127
           D V+NH L+E S T+E +   ++ ++ S  G         + ++    +    TG    I
Sbjct: 904 DEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHI 963

Query: 128 K--HILANFKNY 137
              HIL N+K++
Sbjct: 964 DFGHILGNYKSF 975


>gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1
           precursor [Homo sapiens]
          Length = 459

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 31/124 (25%), Positives = 45/124 (36%), Gaps = 17/124 (13%)

Query: 21  DSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIG-------GNASAEGPEGKGTESTVIT 73
           D ++  E A  L LE     V R    I+  ++G       G+ +A  PEG+G    +  
Sbjct: 272 DGFVMGEGAAVLVLEEYEHAVQR-RARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAA 330

Query: 74  GVD---------SVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAA 124
            +          S +N H   T     A NK IK   K     L     K     + GAA
Sbjct: 331 ALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAA 390

Query: 125 EQIK 128
             ++
Sbjct: 391 GAVE 394


>gi|21071077 dishevelled-associated activator of morphogenesis 1
           [Homo sapiens]
          Length = 1078

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 2/61 (3%)

Query: 77  SVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKN 136
           S +NH+ Q        + K   + +  +K K+E  R    + F +GA +Q+  ++  F N
Sbjct: 765 SRINHYQQRLQSLY--FKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGN 822

Query: 137 Y 137
           Y
Sbjct: 823 Y 823


>gi|13376460 zinc finger protein 556 [Homo sapiens]
          Length = 456

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 13/43 (30%), Positives = 25/43 (58%)

Query: 14 SHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGN 56
          + +++ +   +SQ+   G +L ++ KI   T  NI+ SL+G N
Sbjct: 45 NEAQLKASGSISQQDTSGEKLSLKQKIEKFTRKNIWASLLGKN 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,658,538
Number of Sequences: 37866
Number of extensions: 175669
Number of successful extensions: 449
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 431
Number of HSP's gapped (non-prelim): 19
length of query: 140
length of database: 18,247,518
effective HSP length: 92
effective length of query: 48
effective length of database: 14,763,846
effective search space: 708664608
effective search space used: 708664608
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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