Guide to the Human Genome
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Search of human proteins with 46409448

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46409448 hypothetical protein LOC389649 [Homo sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46409448 hypothetical protein LOC389649 [Homo sapiens]             452   e-128
gi|239752927 PREDICTED: similar to hCG1995379 [Homo sapiens]           32   0.44 
gi|239747492 PREDICTED: hypothetical protein XP_002347548 [Homo ...    32   0.44 
gi|239741366 PREDICTED: hypothetical protein XP_002342186 [Homo ...    32   0.44 
gi|22035682 DBF4 homolog B isoform 1 [Homo sapiens]                    30   1.7  
gi|167234419 thyroid hormone receptor associated protein 3 [Homo...    30   1.7  
gi|21361116 versican isoform 1 [Homo sapiens]                          28   4.8  
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    28   6.3  
gi|118150678 epithelial cell transforming sequence 2 oncogene-li...    28   6.3  
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    28   6.3  
gi|21361699 sphingosine kinase 2 [Homo sapiens]                        28   8.2  
gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens]      28   8.2  

>gi|46409448 hypothetical protein LOC389649 [Homo sapiens]
          Length = 223

 Score =  452 bits (1164), Expect = e-128
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MRPLGKGLLPAEELIRSNLGVGRSLRDCLSQSGKLAEELGSKRLKPAKFGTEGKERVEQR 60
           MRPLGKGLLPAEELIRSNLGVGRSLRDCLSQSGKLAEELGSKRLKPAKFGTEGKERVEQR
Sbjct: 1   MRPLGKGLLPAEELIRSNLGVGRSLRDCLSQSGKLAEELGSKRLKPAKFGTEGKERVEQR 60

Query: 61  TERQRTGSSKEPRMQIICRRRWREPPPRLLWGCLMPRAQPLLHVTAYENTGHWERLASVV 120
           TERQRTGSSKEPRMQIICRRRWREPPPRLLWGCLMPRAQPLLHVTAYENTGHWERLASVV
Sbjct: 61  TERQRTGSSKEPRMQIICRRRWREPPPRLLWGCLMPRAQPLLHVTAYENTGHWERLASVV 120

Query: 121 SSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR 180
           SSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR
Sbjct: 121 SSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR 180

Query: 181 ISGELIGNAHSPAPPRTPELETLGWDKQAVLSGAQVILVCAEV 223
           ISGELIGNAHSPAPPRTPELETLGWDKQAVLSGAQVILVCAEV
Sbjct: 181 ISGELIGNAHSPAPPRTPELETLGWDKQAVLSGAQVILVCAEV 223


>gi|239752927 PREDICTED: similar to hCG1995379 [Homo sapiens]
          Length = 119

 Score = 32.0 bits (71), Expect = 0.44
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%)

Query: 87  PRLLWGCLMPRAQPLLHVTAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPAT 146
           P +LW  L P     L +           L+ + +S  + P+V+  +++++T     P  
Sbjct: 38  PIILWPGLCPLFSSFLPL-----------LSRLRASSRKHPSVLLTTTLTLTSL---PQL 83

Query: 147 LDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR 180
               L+L   K FPV    SPLC  C    E  R
Sbjct: 84  YSPLLILLGSKFFPVLQTLSPLCAACTGLSEGSR 117


>gi|239747492 PREDICTED: hypothetical protein XP_002347548 [Homo
           sapiens]
          Length = 119

 Score = 32.0 bits (71), Expect = 0.44
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%)

Query: 87  PRLLWGCLMPRAQPLLHVTAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPAT 146
           P +LW  L P     L +           L+ + +S  + P+V+  +++++T     P  
Sbjct: 38  PIILWPGLCPLFSSFLPL-----------LSRLRASSRKHPSVLLTTTLTLTSL---PQL 83

Query: 147 LDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR 180
               L+L   K FPV    SPLC  C    E  R
Sbjct: 84  YSPLLILLGSKFFPVLQTLSPLCAACTGLSEGSR 117


>gi|239741366 PREDICTED: hypothetical protein XP_002342186 [Homo
           sapiens]
          Length = 119

 Score = 32.0 bits (71), Expect = 0.44
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%)

Query: 87  PRLLWGCLMPRAQPLLHVTAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPAT 146
           P +LW  L P     L +           L+ + +S  + P+V+  +++++T     P  
Sbjct: 38  PIILWPGLCPLFSSFLPL-----------LSRLRASSRKHPSVLLTTTLTLTSL---PQL 83

Query: 147 LDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR 180
               L+L   K FPV    SPLC  C    E  R
Sbjct: 84  YSPLLILLGSKFFPVLQTLSPLCAACTGLSEGSR 117


>gi|22035682 DBF4 homolog B isoform 1 [Homo sapiens]
          Length = 615

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 71  EPRMQIICRRRWREPPPRLLWGCLMPRAQPLLH 103
           E R  ++  R W  P P + WGCL+P     LH
Sbjct: 498 EARPWLMSARCWVRPFPFVTWGCLIPHDTTPLH 530


>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
           sapiens]
          Length = 955

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 12/80 (15%)

Query: 30  SQSGKLAEELGSKRLKPAKFGTEGKER---VEQRTERQRTGSSKEPRMQIICRRRWREPP 86
           SQ  K +E   SK    A +GT    R   V + + R+R+ + K P   ++ RRR   P 
Sbjct: 211 SQDTKASES--SKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPS 268

Query: 87  PRLLWGCLMPRAQPLLHVTA 106
           P       +P+  P L  T+
Sbjct: 269 P-------VPKPSPPLSSTS 281


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 98  AQPLLHVTAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYP 143
           ++P+  V  + +T   E LA V  S TQ+PT    SS +I  S  P
Sbjct: 934 SKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIP 979


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 30  SQSGKLAEELGSKRLKPAKFGTEGKERVEQRTERQRTGSSKEPRMQIICRRRWREPPPR 88
           S+ GK  +    ++ K  K G E +E+  ++  + +    KE   +   RRR ++ PPR
Sbjct: 641 SEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEE--RRRRQQRPPR 697


>gi|118150678 epithelial cell transforming sequence 2 oncogene-like
           [Homo sapiens]
          Length = 904

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 47  AKFGT--EGKERVEQRTERQRTGSSKEPRMQIICRRR---WREPPPRLLWGC----LMPR 97
           A +GT  E K   E+  ERQR    ++   + I  R+   ++  PP +   C    L PR
Sbjct: 162 ATYGTLNEPKTEDEELLERQREKCLRKRIWEKIALRKKELFKVRPPWVSGTCCSSVLKPR 221

Query: 98  AQPLLHVTAYENTGHWERLASVVSSKTQQPTVISHSSISITFSH 141
            QP L  T  E  G  E L   +   T   T+   S+IS + S+
Sbjct: 222 CQPRLSQTVRERVGLHEALEKQL-VLTSLETLPKRSNISGSHSY 264


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)

Query: 127 PTVISHSSISITFSHYPPATLDSFLVLE-PIKLFPVSSLRSPLCLNCGSCRESIRISGEL 185
           P  +S S   I  SH P + L SFL  E P K    +S +    L  G+         E+
Sbjct: 446 PAALSPSLEPIRCSHQPISLLGSFLTEESPDKEIDQNSQQEESRLRKGTVSSQ---GTEV 502

Query: 186 IGNAHSPAPPRTPE 199
           +  + S  PPRTP+
Sbjct: 503 VFASASVTPPRTPD 516


>gi|21361699 sphingosine kinase 2 [Homo sapiens]
          Length = 654

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 7/53 (13%)

Query: 52  EGKERVEQRTERQRTGS-SKEPRMQIICRRRWREPPPRLLWGCLMPRAQPLLH 103
           E +E+ +QR +++ TGS    PR  ++  +    PPP L        + PLLH
Sbjct: 6   EAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPL------AASTPLLH 52


>gi|4502371 breast cancer antiestrogen resistance 3 [Homo sapiens]
          Length = 825

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 9/92 (9%)

Query: 38  ELGSKRLKPAKFGTEGKERVEQRTERQRTGSSKEPRMQIICRRRWREPPPRLLWGCLMPR 97
           E+    L  A+F  E  +      ER   G   +  M  IC+  ++    RLLWG    +
Sbjct: 738 EIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKTEFQ---MRLLWG---SK 791

Query: 98  AQPLLHVTAYENTGHWERLASVVSSKTQQPTV 129
              +     YE    + ++ + +S K + P V
Sbjct: 792 GAQVNQTERYEK---FNQILTALSRKLEPPPV 820


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,084,234
Number of Sequences: 37866
Number of extensions: 476697
Number of successful extensions: 1412
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1407
Number of HSP's gapped (non-prelim): 13
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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