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Search of human proteins with 46409304
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46409304 glutamate-rich 1 [Homo sapiens]
(443 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46409304 glutamate-rich 1 [Homo sapiens] 893 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 73 5e-13
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 68 1e-11
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 62 8e-10
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 60 5e-09
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 57 4e-08
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 54 2e-07
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 54 2e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 54 3e-07
gi|115529449 upstream binding transcription factor, RNA polymera... 53 5e-07
gi|115529451 upstream binding transcription factor, RNA polymera... 53 5e-07
gi|7657671 upstream binding transcription factor, RNA polymerase... 53 5e-07
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens] 53 6e-07
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 53 6e-07
gi|55956788 nucleolin [Homo sapiens] 51 2e-06
gi|217035154 RCSD domain containing 1 [Homo sapiens] 51 2e-06
gi|21735415 centromere protein B [Homo sapiens] 51 2e-06
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens] 51 2e-06
gi|148746195 trichohyalin [Homo sapiens] 51 2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 2e-06
gi|34878777 ring finger protein 20 [Homo sapiens] 50 4e-06
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 49 7e-06
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 49 7e-06
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 49 7e-06
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 49 9e-06
gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens] 49 9e-06
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 49 9e-06
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 49 9e-06
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 49 1e-05
gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens] 48 2e-05
>gi|46409304 glutamate-rich 1 [Homo sapiens]
Length = 443
Score = 893 bits (2307), Expect = 0.0
Identities = 443/443 (100%), Positives = 443/443 (100%)
Query: 1 MAAHRKHVFVEKVLQRLFPPVPSGQGKREPQTLAVQNPPKKVTSEKVSQKHAEPLTDTGS 60
MAAHRKHVFVEKVLQRLFPPVPSGQGKREPQTLAVQNPPKKVTSEKVSQKHAEPLTDTGS
Sbjct: 1 MAAHRKHVFVEKVLQRLFPPVPSGQGKREPQTLAVQNPPKKVTSEKVSQKHAEPLTDTGS 60
Query: 61 ETPTARRLYTASGPPEGYVPCWPEPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSK 120
ETPTARRLYTASGPPEGYVPCWPEPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSK
Sbjct: 61 ETPTARRLYTASGPPEGYVPCWPEPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSK 120
Query: 121 KKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLA 180
KKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLA
Sbjct: 121 KKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLA 180
Query: 181 AKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEE 240
AKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEE
Sbjct: 181 AKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEE 240
Query: 241 DLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGAD 300
DLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGAD
Sbjct: 241 DLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGAD 300
Query: 301 ASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQEMYFYDGVSRDA 360
ASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQEMYFYDGVSRDA
Sbjct: 301 ASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQEMYFYDGVSRDA 360
Query: 361 ASAALADAAEELLDRLASHSMLPSDVSILYHMKTLLLLQDTERLKHALEMFPEHCTMPPD 420
ASAALADAAEELLDRLASHSMLPSDVSILYHMKTLLLLQDTERLKHALEMFPEHCTMPPD
Sbjct: 361 ASAALADAAEELLDRLASHSMLPSDVSILYHMKTLLLLQDTERLKHALEMFPEHCTMPPD 420
Query: 421 HARVISAFFSYWITHILPEKSSD 443
HARVISAFFSYWITHILPEKSSD
Sbjct: 421 HARVISAFFSYWITHILPEKSSD 443
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 73.2 bits (178), Expect = 5e-13
Identities = 62/244 (25%), Positives = 110/244 (45%), Gaps = 19/244 (7%)
Query: 98 DDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTI 157
++ + +D +Q ++ R + H+ ++ + E E E+++ +E+ +++
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEG 759
Query: 158 SKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGV------ 211
+ ++K++ +RKK + G Q E E EG GE EE G
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819
Query: 212 -----DTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDV 266
+ EE+ GEE+ + EE+G + EE+ +EEG + E+ GEE
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEG-EGEEEEGEGKGEEEGEEGEGEE---EGEEGE 875
Query: 267 KDAREEDGVDTIEEDLTRAG-EEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADA 325
+ EE+G EE+ G EE+G+ EE+G EE+ GE +G + GEE +
Sbjct: 876 GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGKGEEEGEEGEGEG 932
Query: 326 SEED 329
EE+
Sbjct: 933 EEEE 936
Score = 69.7 bits (169), Expect = 5e-12
Identities = 65/267 (24%), Positives = 113/267 (42%), Gaps = 31/267 (11%)
Query: 92 ENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQH 151
E G+ E + ++ + R ++ ++ K+ K + E E+ + +EK +
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 152 TDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEG-----------E 200
+G + + K + +++++ + ++ G + G + E E E
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 201 GVGEACEEDGVDTSEEDPTLAGEEDVKDTR-EEDGADASEEDLTRARQEEGADASE---- 255
G GE EE+G EE+ GEE+ + EE+G EE+ + EE + E
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGE 933
Query: 256 --------EDPTPAGEEDVKD--AREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
ED GEE+ + EE+G EE+ GEE + EE+G EE+
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 306 PTWAGEEEGAD--SGEEDGADASEEDD 330
GEEEG + GEE+G EE++
Sbjct: 994 ---EGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 66.2 bits (160), Expect = 6e-11
Identities = 51/162 (31%), Positives = 74/162 (45%), Gaps = 16/162 (9%)
Query: 191 QPEDSSNEGE--GVGEACEEDGVDTSEEDPTLA---GEEDVKDTREEDGADASEEDLTR- 244
+ E+ EGE G GE EE+G EE+ GEE+ + EDG EE+
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 245 -ARQEEGADASEEDPTPAGEEDVKDAREEDGV-DTIEEDLTRAGEEDGKDTREEDGADAS 302
+EEG EE+ GEE + EE+G + EE+ GEE+G+ E +G
Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015
Query: 303 EEDPTWAGEEEGADS--------GEEDGADASEEDDTITNEK 336
EE+ GE EG + GEE+G + +E + N +
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRR 1057
Score = 59.7 bits (143), Expect = 5e-09
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 10/141 (7%)
Query: 193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTR-EEDGADASEEDLTRARQEEG- 250
E EGEG GE E +G EE+ GEE+ + EE+G EE +EEG
Sbjct: 931 EGEEEEGEGEGEDGEGEG---EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987
Query: 251 ADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG 310
+ EE+ GEE+ + E +G EE+ GE +G+ EE + EE+ G
Sbjct: 988 GEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE----GEVEGEVEGEEGEGEGEEEEGEEEG 1043
Query: 311 EE-EGADSGEEDGADASEEDD 330
EE E GEE+ + EE++
Sbjct: 1044 EEREKEGEGEENRRNREEEEE 1064
Score = 50.1 bits (118), Expect = 4e-06
Identities = 43/155 (27%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 191 QPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEG 250
+ E+ EGE GE E+G EE EE + EE+G + EE+ + EG
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEE------EEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 251 ADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG 310
EE+ GE E+G EE+ GEE+G++ +E + + +
Sbjct: 1012 EGEEEEEGEVEGE-----VEGEEGEGEGEEE---EGEEEGEEREKEGEGEENRRNREEEE 1063
Query: 311 EEEGADSGEEDGADASEEDDTITNEKAHSILNFLK 345
EEEG +E G + +E D +K I +K
Sbjct: 1064 EEEG--KYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Score = 49.7 bits (117), Expect = 5e-06
Identities = 49/219 (22%), Positives = 86/219 (39%), Gaps = 22/219 (10%)
Query: 125 NPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAA 184
N NV + EK + L + TD +S+ K + + + + + G + +
Sbjct: 609 NEENVKVHGGRKEKTEILSDDL-----TDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGS 663
Query: 185 GVSFMYQPEDSSN------------EGEGVGEACEEDGVDT--SEEDPTLAGEEDVKDTR 230
+ +Q E+ GEG E E++ EE E+ + R
Sbjct: 664 SGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKER 723
Query: 231 EEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDG 290
++ + EE+ +EEG EE+ G+E+ + E +G EE + E G
Sbjct: 724 NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE-GEGEEVEGEREKEEGERKKEERAG 782
Query: 291 KDTREEDGAD--ASEEDPTWAGEEEGADSGEEDGADASE 327
K+ + E+ D EE+ T EE + GE +G + E
Sbjct: 783 KEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821
Score = 49.3 bits (116), Expect = 7e-06
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 190 YQPEDSSNEG----EGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRA 245
++ E+ EG EG GE E +G EE EE+ ++ EE+G E +
Sbjct: 955 WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014
Query: 246 RQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
+EEG E + GEE + EE+G + EE E+ + REE+ + +
Sbjct: 1015 EEEEGEVEGEVE----GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070
Query: 306 PTWAGEEEGADSGEE 320
T E E D GEE
Sbjct: 1071 ETGEEENERQD-GEE 1084
Score = 48.1 bits (113), Expect = 2e-05
Identities = 65/253 (25%), Positives = 108/253 (42%), Gaps = 63/253 (24%)
Query: 83 PEPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSL 142
PE G+ E SSG + + +R + K K + + + P E EK+
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDE-----EREKGEKDKGRGEMERPG-------EGEKE--- 695
Query: 143 LQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGV 202
L EK + + DG + ++ + +K++ + + G E+ EGE
Sbjct: 696 LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG--------------EEEHGEGE-- 739
Query: 203 GEACEEDGVDTSEEDPTLAGEED-----VKDTREEDGADASEEDLTRARQEEGADASEED 257
EE+G EE+ G+E+ V+ RE++ + +E+ RA +EE + EE
Sbjct: 740 ----EEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE--RAGKEEKGE--EEG 791
Query: 258 PTPAGEEDVKDAREEDGVDTIEEDLTRAGE-EDGKDTREEDGADASEEDPTWAGEEEGAD 316
GEE+ + R E+ + E + GE E+GK REE+ EEEG
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVE---GGEVEEGKGEREEE-------------EEEG-- 833
Query: 317 SGEEDGADASEED 329
GEE+ + EE+
Sbjct: 834 EGEEEEGEGEEEE 846
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/251 (21%), Positives = 108/251 (43%), Gaps = 16/251 (6%)
Query: 95 SSGDDTEDQDPHDQPKR-RRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTD 153
+ DD+++ + + K + ++H S+ F IE A +++ + +EK + +
Sbjct: 539 TENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIE-AFSDEEVEIPEEKEGAEDSK 597
Query: 154 GTTISKNKKRKLKKKQQIK--RKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGV 211
G I + + ++ ++ RK+ + + + E S + + VGEA EDG
Sbjct: 598 GNGIEEQEVEANEENVKVHGGRKEKTEILSD----DLTDKAEVSEGKAKSVGEA--EDGP 651
Query: 212 ----DTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEED-PTPAGEEDV 266
D + E+ + E + RE+ D ++ R + E A +E+ GEE
Sbjct: 652 EGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE 711
Query: 267 KDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADAS 326
+ RE+ +++ GEE+ + EE+G D EE+ +E + E +G
Sbjct: 712 QKEREQGHQKERNQEMEEGGEEEHGEGEEEEG-DREEEEEKEGEGKEEGEGEEVEGEREK 770
Query: 327 EEDDTITNEKA 337
EE + E+A
Sbjct: 771 EEGERKKEERA 781
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 68.2 bits (165), Expect = 1e-11
Identities = 65/289 (22%), Positives = 126/289 (43%), Gaps = 37/289 (12%)
Query: 94 ASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTD 153
A+ D+ D+ D+ K++ ++ K K+K K P+ ++ + E L +E+ +++ +
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQ-EALAKLKEEEERQKREE 362
Query: 154 GTTISK---------------NKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNE 198
I + +KR+ KK+++ +RK+ K G ++
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERL----KKEGKLLTKSQREARAR 418
Query: 199 GEGVGEACEEDGVDTSEED------PTLAGEEDVKDTREEDGADASEE-DLTRARQ--EE 249
E + + GV+ +D P ++ K ++ + + SE +L A + E+
Sbjct: 419 AEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ 478
Query: 250 GADASEEDPTPAG---EEDVKDAREEDGVDTIEEDLTRAGEEDG-----KDTREEDGADA 301
G EE P P EED +DA +D ++ T E + K+ EE+ +
Sbjct: 479 GVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Query: 302 SEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQEM 350
EE+ EEE + GE +G++ EED+ +++EK K ++EM
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Score = 56.6 bits (135), Expect = 4e-08
Identities = 58/264 (21%), Positives = 122/264 (46%), Gaps = 33/264 (12%)
Query: 98 DDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTI 157
++ E Q ++ + +R+ + ++K+K + +EQ + E+++ +E+ +R +G +
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEER----LEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 158 SKNKKR-KLKKKQQIKRKKAAGLAAKAAGVSFMYQP--EDSSN-------EGEGVGEACE 207
+K+++ + + + +K +A G+ + +P ED E + V E+ E
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468
Query: 208 --------EDGVDTSEEDPTLAGEEDVKDTREEDGAD-----ASEEDLTRARQEEGADAS 254
E GV EE P E+ +DT E+ G D AS+E+ + +
Sbjct: 469 LCAAVEVMEQGVPEKEETPPPVEPEEEEDT-EDAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 255 EEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEG 314
+E+P EE+ ++ EE+ + EE+ GE +G + EED + E+D +++
Sbjct: 528 KENP----EEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP 583
Query: 315 ADSGEEDGADASEEDDTITNEKAH 338
+ D ++ +DD E+A+
Sbjct: 584 SKEMSSD-SEYDSDDDRTKEERAY 606
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/233 (24%), Positives = 104/233 (44%), Gaps = 31/233 (13%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIE-----QAELEKQQSLLQEK-----SQRQ 150
E++ ++ +R++ ++ + K++ K +L + +A E LLQ + S+
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438
Query: 151 HTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEED- 209
I ++KKRK K QQ++ K+ + A V M Q E E EE+
Sbjct: 439 LPKKRPIYEDKKRK-KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEED 497
Query: 210 ----GVD------TSEEDPTLAGEE---DVKDTREEDGADASEEDLTRARQEEGADASEE 256
G+D + EE + G + +VK+ EE+ + EE+ +EE + E
Sbjct: 498 TEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGES 557
Query: 257 DPTPAGEEDVKDAREEDGVDTIE----EDLTRAGEEDGKD--TREEDGADASE 303
+ + EED K + E+D T++ ++++ E D D T+EE D ++
Sbjct: 558 EGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAK 610
Score = 39.3 bits (90), Expect = 0.007
Identities = 48/242 (19%), Positives = 97/242 (40%), Gaps = 45/242 (18%)
Query: 96 SGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGT 155
SG D +D D + PK+ + + KS KK+ DG+
Sbjct: 135 SGSD-DDDDFNKLPKKAKGKAQKSNKKW-----------------------------DGS 164
Query: 156 TISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNE-GEGVGEACEEDGVDTS 214
++ +K+K++ +I +G + S Q ++ N+ G + E+D D S
Sbjct: 165 EEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD--DAS 222
Query: 215 EEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDG 274
+ T+A ++ K RE D + L + +++E + ++D + K+++ +
Sbjct: 223 FKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKD-----QSKQKESQRKFE 277
Query: 275 VDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITN 334
+T++ +T DT ++ E PT A ++ D ++D E +
Sbjct: 278 EETVKSKVT-------VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK 330
Query: 335 EK 336
EK
Sbjct: 331 EK 332
Score = 38.9 bits (89), Expect = 0.009
Identities = 46/228 (20%), Positives = 96/228 (42%), Gaps = 25/228 (10%)
Query: 115 RKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKR- 173
+K+KS+ K+ ++ AE+E + +++ Q+ SK KK+K KKKQ
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQK--------SKGKKKKEKKKQDFDED 56
Query: 174 ---KKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEE---DVK 227
K+ L+ +A G+ D E EE+ ++ G++ D
Sbjct: 57 DILKELEELSLEAQGIK-----ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDN 111
Query: 228 DTREEDGADASEEDLTRARQEEGADASEED-----PTPAGEEDVKDAREEDGVDTIEEDL 282
D+ E + D+ + + + E + + ++D P A + K ++ DG + E++
Sbjct: 112 DSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNS 171
Query: 283 TRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
+ E ++ E G ++ E + G+++ + ++ EDD
Sbjct: 172 KKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD 219
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 62.4 bits (150), Expect = 8e-10
Identities = 41/106 (38%), Positives = 50/106 (47%)
Query: 224 EDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLT 283
ED + REED SEED R +E+ E+D EED + EED +EED
Sbjct: 577 EDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFR 636
Query: 284 RAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
R+ ED + EED EED W EE+ EED EED
Sbjct: 637 RSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEED 682
Score = 60.8 bits (146), Expect = 2e-09
Identities = 54/164 (32%), Positives = 70/164 (42%), Gaps = 5/164 (3%)
Query: 188 FMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQ 247
F + PED + E EED SEED EED + E+D EED R +
Sbjct: 565 FRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLE 624
Query: 248 EEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPT 307
E+ EED + ED + EED EEDL EED + EED EED
Sbjct: 625 EDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFR 684
Query: 308 WAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQEMY 351
+ E E+D EED + E+ +F +S QE +
Sbjct: 685 RPLQGEWRRPPEDDFRRPPEEDFRHSPEE-----DFRQSPQEHF 723
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/82 (35%), Positives = 36/82 (43%)
Query: 207 EEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDV 266
EED EED EED + EED EED R Q E E+D EED
Sbjct: 648 EEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRPPEEDF 707
Query: 267 KDAREEDGVDTIEEDLTRAGEE 288
+ + EED + +E R +E
Sbjct: 708 RHSPEEDFRQSPQEHFRRPPQE 729
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/68 (33%), Positives = 34/68 (50%)
Query: 239 EEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDG 298
+E R+R+E+ +ED +ED + +ED EED +ED + EED
Sbjct: 792 QEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDL 851
Query: 299 ADASEEDP 306
+A EEDP
Sbjct: 852 REAPEEDP 859
Score = 36.6 bits (83), Expect = 0.047
Identities = 23/67 (34%), Positives = 31/67 (46%)
Query: 223 EEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDL 282
+E + +REED +ED E+ +ED EED + +ED EEDL
Sbjct: 792 QEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDL 851
Query: 283 TRAGEED 289
A EED
Sbjct: 852 REAPEED 858
Score = 35.4 bits (80), Expect = 0.10
Identities = 25/82 (30%), Positives = 37/82 (45%)
Query: 240 EDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGA 299
E R QE +E + EED + +ED +ED +ED + +EED
Sbjct: 777 EHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFR 836
Query: 300 DASEEDPTWAGEEEGADSGEED 321
S+ED EE+ ++ EED
Sbjct: 837 CPSDEDFRQLPEEDLREAPEED 858
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/67 (32%), Positives = 32/67 (47%)
Query: 263 EEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDG 322
+E + +REED +ED +ED + +ED EED +E+ EED
Sbjct: 792 QEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDL 851
Query: 323 ADASEED 329
+A EED
Sbjct: 852 REAPEED 858
Score = 35.4 bits (80), Expect = 0.10
Identities = 20/59 (33%), Positives = 31/59 (52%)
Query: 215 EEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREED 273
EED +ED + +ED +ED ++E+ S+ED EED+++A EED
Sbjct: 800 EEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEED 858
Score = 34.3 bits (77), Expect = 0.23
Identities = 24/75 (32%), Positives = 33/75 (44%)
Query: 239 EEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDG 298
+E R QE + EED +ED + +ED +ED EED + +ED
Sbjct: 784 QEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDF 843
Query: 299 ADASEEDPTWAGEEE 313
EED A EE+
Sbjct: 844 RQLPEEDLREAPEED 858
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/75 (28%), Positives = 34/75 (45%)
Query: 223 EEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDL 282
+E + +E + EED E+ +ED +ED + +EED +ED
Sbjct: 784 QEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDF 843
Query: 283 TRAGEEDGKDTREED 297
+ EED ++ EED
Sbjct: 844 RQLPEEDLREAPEED 858
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Query: 207 EEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDP------TP 260
+ED +ED +ED + +EED S+ED + +E+ +A EEDP P
Sbjct: 808 DEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEEDPRLPDNFRP 867
Query: 261 AGEE 264
GE+
Sbjct: 868 PGED 871
Score = 30.0 bits (66), Expect = 4.4
Identities = 20/59 (33%), Positives = 25/59 (42%)
Query: 207 EEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEED 265
EED +ED +ED + +ED EED E+ EED A EED
Sbjct: 800 EEDFRHPPDEDFRGPPDEDFRHPPDEDFRSPQEEDFRCPSDEDFRQLPEEDLREAPEED 858
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 59.7 bits (143), Expect = 5e-09
Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 17/175 (9%)
Query: 160 NKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPT 219
+ RK+K K + + A A E+ NE GEA E P
Sbjct: 40 SSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEA-------KITEAP- 91
Query: 220 LAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE 279
A E+++ + +EE+ DA+E+ ++E A ++ +ED +D EE G + +
Sbjct: 92 -ASEKEIVEVKEENIEDATEKG---GEKKEAVAAEVKNEEEDQKEDEEDQNEEKG-EAGK 146
Query: 280 EDLTRAGEEDGKDTRE--EDGADASEEDPTWAGEEE--GADSGEEDGADASEEDD 330
ED GEEDGK+ + E G DA E++ GE+ + G+E G D EE+D
Sbjct: 147 EDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEED 201
Score = 55.5 bits (132), Expect = 1e-07
Identities = 70/260 (26%), Positives = 116/260 (44%), Gaps = 32/260 (12%)
Query: 105 PHDQPKRRRI-RKHKSKKKFKNPNNVLIEQAELE-KQQSLLQEKSQRQHTDG----TTIS 158
P +PKR RK K+K N QA E KQ+++++E +G T
Sbjct: 32 PEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAP 91
Query: 159 KNKKRKLK-KKQQIKRKKAAGLAAKAAGVSFMY-----QPEDSSNEGEGVGEACEEDGVD 212
++K ++ K++ I+ G K A + + Q ED ++ E GEA +ED +
Sbjct: 92 ASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDE 151
Query: 213 TSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQE---EGADASEEDPTPAGEEDVKDA 269
EED G+ED E G DA E++ + ++ G D E+ EED K+
Sbjct: 152 KGEED----GKEDKNGN--EKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTR-------EEDGADASEEDPTWAGEEEGADSGEEDG 322
DG + E+ + +++GKD + EDG + + AG+E+ EE+G
Sbjct: 206 --GDGKEN-EDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
Query: 323 ADASE-EDDTITNEKAHSIL 341
+ E ++D E+ SI+
Sbjct: 263 KEEDEIKEDDGKKEEPQSIV 282
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 56.6 bits (135), Expect = 4e-08
Identities = 49/268 (18%), Positives = 117/268 (43%), Gaps = 26/268 (9%)
Query: 92 ENASSGD-------DTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQ 144
ENA+SG D +++ QP + + S+ + + ++ +E +S
Sbjct: 32 ENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEAS 91
Query: 145 EKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLA--------AKAAGVSFMYQPEDSS 196
E+S + D + + ++ + + + ++ G + KA + ED S
Sbjct: 92 ERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKS 151
Query: 197 NEG--EGVGEACEEDGVDTSEEDPTLAGEEDVK--DTREEDGADASEEDLTRARQEEGAD 252
++ E + + +E+ S+ED ++D K +T +E+ S+++ + +EE A+
Sbjct: 152 DQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKAN 211
Query: 253 ASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEE 312
+ +E P + +D K ++ E+ + +E+ +++ AS+E+ + +E
Sbjct: 212 SDDERPVASDNDDEKQNSDD-------EEQPQLSDEEKMQNSDDERPQASDEEHRHSDDE 264
Query: 313 EGADSGEEDGADASEEDDTITNEKAHSI 340
E D E + ED+ + ++ ++I
Sbjct: 265 EEQDHKSESARGSDSEDEVLRMKRKNAI 292
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 21/162 (12%)
Query: 194 DSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVK----DTREEDGA-------DASEEDL 242
DS ++ E G ++ +++ +G+ K D E++GA + SE
Sbjct: 26 DSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSD 85
Query: 243 TRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEED----------LTRAGEEDGKD 292
R+ E +D + DP+ + +A +D + D +A +D K
Sbjct: 86 NRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKW 145
Query: 293 TREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITN 334
RE+ + +E + +EE A +ED S++D+ + N
Sbjct: 146 GREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQN 187
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 12/124 (9%)
Query: 228 DTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGE 287
+ ++ D S+ D A A SE D G+ +E G D+ +E +
Sbjct: 17 ERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSG 76
Query: 288 EDGKDTREEDGADASE------EDPTWAGEEEGADSGEEDGADASEED------DTITNE 335
D R ++ ++ASE DP+ + G+++ +D + D + +E
Sbjct: 77 SDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSE 136
Query: 336 KAHS 339
KAHS
Sbjct: 137 KAHS 140
Score = 34.3 bits (77), Expect = 0.23
Identities = 48/242 (19%), Positives = 95/242 (39%), Gaps = 23/242 (9%)
Query: 94 ASSGDDTEDQDPHD--------QPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQE 145
AS D ED DP D P H+S + E+A + ++ ++
Sbjct: 90 ASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGRED 149
Query: 146 KSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEA 205
KS + + S +++R + + + + K +P+ S +E + +
Sbjct: 150 KSDQSDDEKIQNSDDEERAQGSDED--KLQNSDDDEKMQNTDDEERPQLSDDERQ---QL 204
Query: 206 CEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEED 265
EE+ ++ +E P + +D K ++ +E+ + EE S+++ A +E+
Sbjct: 205 SEEEKANSDDERPVASDNDDEKQ-------NSDDEEQPQLSDEEKMQNSDDERPQASDEE 257
Query: 266 VKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEED---G 322
+ + +E+ D E + ED + A AS+ + E +SG D G
Sbjct: 258 HRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGG 317
Query: 323 AD 324
AD
Sbjct: 318 AD 319
Score = 31.2 bits (69), Expect = 2.0
Identities = 20/99 (20%), Positives = 38/99 (38%)
Query: 237 ASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREE 296
A EDL + + A+ + D + D ++A E D G+ +E
Sbjct: 2 ADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKEL 61
Query: 297 DGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
G D+ +E + + ++ ++ASE D N+
Sbjct: 62 FGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDND 100
Score = 30.0 bits (66), Expect = 4.4
Identities = 35/130 (26%), Positives = 48/130 (36%), Gaps = 15/130 (11%)
Query: 217 DPTLAGEEDVKDTREEDGADASEEDLTRARQEE----GADASEEDPT-----PAGEEDVK 267
DP E +K E A E R +E+ G AS +P GEE +
Sbjct: 527 DPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESIS 586
Query: 268 DAREEDGVDT-IEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADAS 326
A ++ I E+ R D + EED A + +EEG SG+
Sbjct: 587 LAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKR-----K 641
Query: 327 EEDDTITNEK 336
EDD N+K
Sbjct: 642 AEDDDKANKK 651
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 35/215 (16%)
Query: 192 PEDSSNEG---EGVGEACEEDGVDTSEEDPTLAGEED----------VKDTREEDG-ADA 237
PE S EG G +C + ++ E +P EED +K+ EE+G A
Sbjct: 463 PEKESEEGCPKRGFEGSCSQK--ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKE 520
Query: 238 SEEDLTRARQEE---GADASEEDPTPAGEEDVKDAREEDGVDT------IEEDLTRAGEE 288
SE+DL + +EE ++ E+D +ED + + EDG + +E+DL G E
Sbjct: 521 SEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSE 580
Query: 289 D-------GKDTREEDGADASEED--PTWAGEEEGADSGEEDGADASEEDDTITNEKAHS 339
K+ E D ++ ED +EEG++ ++ +D EE++ T EK
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEED-TYEKVFD 639
Query: 340 ILNFLKSTQEMYFYDGVSRDAASAALADAAEELLD 374
+ K +E G+ A DA E+L +
Sbjct: 640 DESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Score = 48.5 bits (114), Expect = 1e-05
Identities = 71/307 (23%), Positives = 112/307 (36%), Gaps = 40/307 (13%)
Query: 45 EKVSQKHAEPLTDTGS--ETPTARRLYTASGPPEGYVPCWPEPSSCGSP----ENASSGD 98
E + +K E D G E + +S E C + S G P E + S
Sbjct: 424 EPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 99 DTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTIS 158
++E+ +P + +K KK KN E+ L K+ K + T S
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKND----CEENGLAKESEDDLNKESEEEVGPTKES 539
Query: 159 KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSN---EGEGVGEACEEDGVDTSE 215
+ + + + K Q ED S E G+ + +E+G +
Sbjct: 540 EEDDSEKESDEDCSEK----------------QSEDGSEREFEENGLEKDLDEEGSEKEL 583
Query: 216 EDPTLAGEEDVKDTR----EEDGADA--SEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+ L E + D+ E+DG++ EE R E+ + EE+ T D +
Sbjct: 584 HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESD 643
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
+ED EE G E EE AD + + E+E AD E + AD +
Sbjct: 644 EKED-----EEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFE 698
Query: 330 DTITNEK 336
D +NEK
Sbjct: 699 DDDSNEK 705
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/236 (19%), Positives = 98/236 (41%), Gaps = 23/236 (9%)
Query: 91 PENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKN---PNNVLIEQAELEKQQSLLQEKS 147
P S DD+E + D +++ + S+++F+ ++ E +E E +++L ++
Sbjct: 535 PTKESEEDDSEKESDEDCSEKQS--EDGSEREFEENGLEKDLDEEGSEKELHENVLDKEL 592
Query: 148 QRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACE 207
+ ++ + + K+ ++ +R+ + D E E E
Sbjct: 593 EENDSENSEFEDDGSEKVLDEEGSERE--------------FDEDSDEKEEEEDTYEKVF 638
Query: 208 EDGVDTSEEDPTLAGEEDVK--DTREEDGADASEEDLTRARQEEGADASEEDPTPAGEED 265
+D D +ED A E+ ++ D + E+G DA E+ + +E DA ++ A E+
Sbjct: 639 DDESD-EKEDEEYADEKGLEAADKKAEEG-DADEKLFEESDDKEDEDADGKEVEDADEKL 696
Query: 266 VKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEED 321
+D + + EED + +D + G + EE P G S ++D
Sbjct: 697 FEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDD 752
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 35/215 (16%)
Query: 192 PEDSSNEG---EGVGEACEEDGVDTSEEDPTLAGEED----------VKDTREEDG-ADA 237
PE S EG G +C + ++ E +P EED +K+ EE+G A
Sbjct: 463 PEKESEEGCPKRGFEGSCSQK--ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKE 520
Query: 238 SEEDLTRARQEE---GADASEEDPTPAGEEDVKDAREEDGVDT------IEEDLTRAGEE 288
SE+DL + +EE ++ E+D +ED + + EDG + +E+DL G E
Sbjct: 521 SEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSE 580
Query: 289 D-------GKDTREEDGADASEED--PTWAGEEEGADSGEEDGADASEEDDTITNEKAHS 339
K+ E D ++ ED +EEG++ ++ +D EE++ T EK
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEED-TYEKVFD 639
Query: 340 ILNFLKSTQEMYFYDGVSRDAASAALADAAEELLD 374
+ K +E G+ A DA E+L +
Sbjct: 640 DESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Score = 48.5 bits (114), Expect = 1e-05
Identities = 71/307 (23%), Positives = 112/307 (36%), Gaps = 40/307 (13%)
Query: 45 EKVSQKHAEPLTDTGS--ETPTARRLYTASGPPEGYVPCWPEPSSCGSP----ENASSGD 98
E + +K E D G E + +S E C + S G P E + S
Sbjct: 424 EPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 99 DTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTIS 158
++E+ +P + +K KK KN E+ L K+ K + T S
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKND----CEENGLAKESEDDLNKESEEEVGPTKES 539
Query: 159 KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSN---EGEGVGEACEEDGVDTSE 215
+ + + + K Q ED S E G+ + +E+G +
Sbjct: 540 EEDDSEKESDEDCSEK----------------QSEDGSEREFEENGLEKDLDEEGSEKEL 583
Query: 216 EDPTLAGEEDVKDTR----EEDGADA--SEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+ L E + D+ E+DG++ EE R E+ + EE+ T D +
Sbjct: 584 HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESD 643
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
+ED EE G E EE AD + + E+E AD E + AD +
Sbjct: 644 EKED-----EEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFE 698
Query: 330 DTITNEK 336
D +NEK
Sbjct: 699 DDDSNEK 705
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/236 (19%), Positives = 98/236 (41%), Gaps = 23/236 (9%)
Query: 91 PENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKN---PNNVLIEQAELEKQQSLLQEKS 147
P S DD+E + D +++ + S+++F+ ++ E +E E +++L ++
Sbjct: 535 PTKESEEDDSEKESDEDCSEKQS--EDGSEREFEENGLEKDLDEEGSEKELHENVLDKEL 592
Query: 148 QRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACE 207
+ ++ + + K+ ++ +R+ + D E E E
Sbjct: 593 EENDSENSEFEDDGSEKVLDEEGSERE--------------FDEDSDEKEEEEDTYEKVF 638
Query: 208 EDGVDTSEEDPTLAGEEDVK--DTREEDGADASEEDLTRARQEEGADASEEDPTPAGEED 265
+D D +ED A E+ ++ D + E+G DA E+ + +E DA ++ A E+
Sbjct: 639 DDESD-EKEDEEYADEKGLEAADKKAEEG-DADEKLFEESDDKEDEDADGKEVEDADEKL 696
Query: 266 VKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEED 321
+D + + EED + +D + G + EE P G S ++D
Sbjct: 697 FEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDD 752
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 53.9 bits (128), Expect = 3e-07
Identities = 68/337 (20%), Positives = 131/337 (38%), Gaps = 41/337 (12%)
Query: 44 SEKVSQKHAEPLTDTGSETPTARRLYTASGPPEGYVPCWPEPSSCGSPENASSGDDTEDQ 103
SE + + AE SE A + + EG PE +PE + E++
Sbjct: 1958 SEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQ--PESEDVEAPEAEGEMQEAEEE 2015
Query: 104 DPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKR 163
QP+ + + E+A+ + ++ E + +DG + ++
Sbjct: 2016 A---QPESDGVEAQPKSEG---------EEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063
Query: 164 KLKKKQQIKRKKAAGL-------AAKAAGVSFMYQPEDSSNEG-EGVGEACEEDGVDTSE 215
+ + +++ + A +A G + QPE E E GEA + +G++ E
Sbjct: 2064 AQEAEGEVQEAEGEAHPESEDVDAQEAEGEA---QPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 216 EDPTL--------AGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK 267
+ A E + + E +G +A + + + EG +A E + E +
Sbjct: 2121 TEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGV 2180
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASE 327
+A E +G E + A E +G+ E +G +A E + E EG ++ E +G E
Sbjct: 2181 EAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPE 2240
Query: 328 EDDTITNEKAHSILNFLKSTQEMYFYDGVSRDAASAA 364
+ EK K + ++ DG S +A+ ++
Sbjct: 2241 SEGETQGEK--------KGSPQVSLGDGQSEEASESS 2269
Score = 49.7 bits (117), Expect = 5e-06
Identities = 42/158 (26%), Positives = 65/158 (41%), Gaps = 22/158 (13%)
Query: 194 DSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDV---KDTREEDGADASE----------- 239
++ EGEG+ E E G + ED L GE +D + DGA+ E
Sbjct: 1789 EAEQEGEGISERGETGGQGSGHED-NLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE 1847
Query: 240 -------EDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKD 292
E A++ EG E + A E + + E + V+T E + E +G +
Sbjct: 1848 SEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAE 1907
Query: 293 TREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
E + E + A E EG D E +GA+A E ++
Sbjct: 1908 APEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Score = 43.5 bits (101), Expect = 4e-04
Identities = 60/285 (21%), Positives = 114/285 (40%), Gaps = 45/285 (15%)
Query: 75 PEGYVPCWPEPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQA 134
PE PE +PE + D ++ + QP+ + +++ + Q
Sbjct: 1838 PEAEGEAQPESEGVEAPE---AEGDAQEAEGEAQPESEDVEAPEAEGE---------AQP 1885
Query: 135 ELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPED 194
E E ++ E + ++G + +K + + ++ + G + + + E+
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Query: 195 SSNEGEGVGEACEEDGVDTSE-EDPTLAGEEDVK------DTREEDGADASEEDLTRARQ 247
++ E EG + E + +++ E E+ EDV+ +T+E +G E + A +
Sbjct: 1946 AAQEAEGQTQP-ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE 2004
Query: 248 EEG------------ADASEEDPTPAGEEDVK----------DAR-EEDGVDTIEEDLTR 284
EG +D E P GEE + DA+ E DGV+ E +
Sbjct: 2005 AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE-EE 2063
Query: 285 AGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
A E +G + +E +G E + A E EG E +G +A E +
Sbjct: 2064 AQEAEG-EVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
Score = 42.4 bits (98), Expect = 9e-04
Identities = 66/314 (21%), Positives = 120/314 (38%), Gaps = 42/314 (13%)
Query: 52 AEPLTDTGSETPTARRLYTAS----------GPPEGYVPCWPEPS--SCGSPENASSGDD 99
++ L D GS T T+S G E VPC + + + G+ + +
Sbjct: 1178 SQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQ 1237
Query: 100 TEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISK 159
D ++ P ++ F N E E ++ + QR ++ +++
Sbjct: 1238 RPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERD---SEEQRASSNLEQLAE 1294
Query: 160 NKKRKLKKKQQIKR-KKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
N ++ + ++ K + GL +A + E EG + E E +G EE+
Sbjct: 1295 NTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEA 1354
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGE---EDVKDAREEDGV 275
L E++++T E QEEG E P G E +++ +E+G+
Sbjct: 1355 QL---EEIEETGGE------------GLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGL 1399
Query: 276 ----DTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEE----EGADSGEEDGADASE 327
++L+ A DGK ++E+D E A E EG + E + SE
Sbjct: 1400 PEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSE 1459
Query: 328 EDDTITNEKAHSIL 341
D + + ++ S L
Sbjct: 1460 TDPSASERQSGSQL 1473
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/227 (21%), Positives = 83/227 (36%), Gaps = 27/227 (11%)
Query: 144 QEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEG-EGV 202
Q+ Q +G + + + + ++ +A G A +A G + QPE E E
Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEA---QPESEDVEAPEAE 1880
Query: 203 GEAC-----------------EEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRA 245
GEA E +G + E + E + + E +G D E + A
Sbjct: 1881 GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEA 1940
Query: 246 RQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
++ E A E T E ++ E+ ED+ E +T+E +G E +
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVE--VETQEAEGEAQPESE 1998
Query: 306 PTWAGEEEG----ADSGEEDGADASEEDDTITNEKAHSILNFLKSTQ 348
A E EG A+ + +D E E+A + + T+
Sbjct: 1999 DVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTE 2045
Score = 38.1 bits (87), Expect = 0.016
Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 16/189 (8%)
Query: 132 EQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKK----QQIKRKKAAGLAAKAA--G 185
E +LE+ + E Q + I + L+++ +++K GL +A G
Sbjct: 1334 EGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEG 1393
Query: 186 VSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRA 245
+ PE+ S G+ + EA DG + E+DP ++ + R A+ + T
Sbjct: 1394 LKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPV----QEEEAGRASASAEPCPAEGTEE 1449
Query: 246 RQEEGADASEEDPT----PAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGA-- 299
E + SE DP+ +G + + G + ++ T+A G R A
Sbjct: 1450 PTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACS 1509
Query: 300 DASEEDPTW 308
A + DP W
Sbjct: 1510 AALDCDPIW 1518
Score = 37.7 bits (86), Expect = 0.021
Identities = 35/183 (19%), Positives = 75/183 (40%), Gaps = 4/183 (2%)
Query: 133 QAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQP 192
Q E K + LQE+ + T + ++ + + ++I+ GL + + + +
Sbjct: 1321 QLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEG 1380
Query: 193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGAD 252
+ +GE + E +E+G+ E+ ++ G+E + + DG + E+D + + A
Sbjct: 1381 PEGGLQGEALEEGLKEEGL---PEEGSVHGQE-LSEASSPDGKGSQEDDPVQEEEAGRAS 1436
Query: 253 ASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEE 312
AS E G E+ + ++G + + GA ++ T A
Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPT 1496
Query: 313 EGA 315
+GA
Sbjct: 1497 QGA 1499
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 53.1 bits (126), Expect = 5e-07
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 23/177 (12%)
Query: 131 IEQAELEKQQSLLQE--KSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSF 188
I Q++ E + L +E K + H D S + + + K+ I K+ + K G +
Sbjct: 570 ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKS--MTKLRGPN- 626
Query: 189 MYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQE 248
P+ S + E+ E+D D +ED E+D EDG D+SE
Sbjct: 627 ---PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--------- 674
Query: 249 EGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
+S ED + G+E+ +D +ED D ++D E +G + D+S+ D
Sbjct: 675 ----SSSEDESEDGDENEEDDEDED--DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 45.8 bits (107), Expect = 8e-05
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 243 TRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE---EDLTRAGEEDGKDTREEDGA 299
+ + +++ D +ED E+D EDG D+ E ED + G+E+ +D +ED
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
Query: 300 DASEEDPTWAGEEEGADSGEEDGADASEED 329
+ +ED E EG+ S D+S+ D
Sbjct: 698 EDDDEDED--NESEGSSSSSSSSGDSSDSD 725
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE---EDPTWAGEEEGADSGEEDGAD 324
++ E+D D +ED E+D EDG D+SE ED + G+E D +ED +
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 325 ASEEDDTITNEKAHS 339
+ED+ +E + S
Sbjct: 699 DDDEDEDNESEGSSS 713
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/77 (28%), Positives = 36/77 (46%)
Query: 263 EEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDG 322
E+D +D +ED + E+D EDG D+ E D SE+ ++E D E+D
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 701
Query: 323 ADASEEDDTITNEKAHS 339
D E + ++ + S
Sbjct: 702 EDEDNESEGSSSSSSSS 718
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 277 TIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
T + + + E+D +D +ED + E+D E+G DS E D SE+ D
Sbjct: 632 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 53.1 bits (126), Expect = 5e-07
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 23/177 (12%)
Query: 131 IEQAELEKQQSLLQE--KSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSF 188
I Q++ E + L +E K + H D S + + + K+ I K+ + K G +
Sbjct: 570 ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKS--MTKLRGPN- 626
Query: 189 MYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQE 248
P+ S + E+ E+D D +ED E+D EDG D+SE
Sbjct: 627 ---PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--------- 674
Query: 249 EGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
+S ED + G+E+ +D +ED D ++D E +G + D+S+ D
Sbjct: 675 ----SSSEDESEDGDENEEDDEDED--DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 45.8 bits (107), Expect = 8e-05
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 243 TRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE---EDLTRAGEEDGKDTREEDGA 299
+ + +++ D +ED E+D EDG D+ E ED + G+E+ +D +ED
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
Query: 300 DASEEDPTWAGEEEGADSGEEDGADASEED 329
+ +ED E EG+ S D+S+ D
Sbjct: 698 EDDDEDED--NESEGSSSSSSSSGDSSDSD 725
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE---EDPTWAGEEEGADSGEEDGAD 324
++ E+D D +ED E+D EDG D+SE ED + G+E D +ED +
Sbjct: 639 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 698
Query: 325 ASEEDDTITNEKAHS 339
+ED+ +E + S
Sbjct: 699 DDDEDEDNESEGSSS 713
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/77 (28%), Positives = 36/77 (46%)
Query: 263 EEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDG 322
E+D +D +ED + E+D EDG D+ E D SE+ ++E D E+D
Sbjct: 642 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 701
Query: 323 ADASEEDDTITNEKAHS 339
D E + ++ + S
Sbjct: 702 EDEDNESEGSSSSSSSS 718
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 277 TIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
T + + + E+D +D +ED + E+D E+G DS E D SE+ D
Sbjct: 632 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 685
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 53.1 bits (126), Expect = 5e-07
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 23/177 (12%)
Query: 131 IEQAELEKQQSLLQE--KSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSF 188
I Q++ E + L +E K + H D S + + + K+ I K+ + K G +
Sbjct: 607 ISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKS--MTKLRGPN- 663
Query: 189 MYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQE 248
P+ S + E+ E+D D +ED E+D EDG D+SE
Sbjct: 664 ---PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--------- 711
Query: 249 EGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEED 305
+S ED + G+E+ +D +ED D ++D E +G + D+S+ D
Sbjct: 712 ----SSSEDESEDGDENEEDDEDED--DDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 45.8 bits (107), Expect = 8e-05
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 243 TRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE---EDLTRAGEEDGKDTREEDGA 299
+ + +++ D +ED E+D EDG D+ E ED + G+E+ +D +ED
Sbjct: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 734
Query: 300 DASEEDPTWAGEEEGADSGEEDGADASEED 329
+ +ED E EG+ S D+S+ D
Sbjct: 735 EDDDEDED--NESEGSSSSSSSSGDSSDSD 762
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE---EDPTWAGEEEGADSGEEDGAD 324
++ E+D D +ED E+D EDG D+SE ED + G+E D +ED +
Sbjct: 676 ESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDE 735
Query: 325 ASEEDDTITNEKAHS 339
+ED+ +E + S
Sbjct: 736 DDDEDEDNESEGSSS 750
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/77 (28%), Positives = 36/77 (46%)
Query: 263 EEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDG 322
E+D +D +ED + E+D EDG D+ E D SE+ ++E D E+D
Sbjct: 679 EDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 738
Query: 323 ADASEEDDTITNEKAHS 339
D E + ++ + S
Sbjct: 739 EDEDNESEGSSSSSSSS 755
Score = 36.2 bits (82), Expect = 0.061
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 277 TIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
T + + + E+D +D +ED + E+D E+G DS E D SE+ D
Sbjct: 669 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGD 722
>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 851
Score = 52.8 bits (125), Expect = 6e-07
Identities = 50/201 (24%), Positives = 78/201 (38%), Gaps = 16/201 (7%)
Query: 192 PEDSSNEGEGVGE--------ACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLT 243
PED+ G+ + + E GVD E+ P A + +EEDG ED +
Sbjct: 123 PEDARPTEHGIDQEEDGPEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGP----EDAS 178
Query: 244 RARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDG-KDTREEDGADAS 302
E G D E+ P A + +EEDG + +EDG +D R +
Sbjct: 179 PTEHEHGVDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHGVDQEDGPEDARPTEHGVDQ 238
Query: 303 EEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQE---MYFYDGVSRD 359
E+ P A E E+ DAS + + + + FL S ++ + F S
Sbjct: 239 EDGPEDARPTEHGVDQEDGPEDASRTEHGVGHRAGRACAAFLSSRRDNLYLSFKKANSAH 298
Query: 360 AASAALADAAEELLDRLASHS 380
+ + ELLD + H+
Sbjct: 299 VTGIISSRSDSELLDWNSKHT 319
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/152 (32%), Positives = 63/152 (41%), Gaps = 26/152 (17%)
Query: 192 PEDSSNEGEGVGE-------ACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTR 244
PED+S GV + + E GVD E+ P A + +EEDG + + LT
Sbjct: 90 PEDASPTEHGVNQEDGPEDASPTEHGVDQQEDGPEDARPTEHGIDQEEDGPE--DASLT- 146
Query: 245 ARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEE 304
E G D E+ P A E G+D EED G ED T E G D E+
Sbjct: 147 ---EHGVDQQEDGPEDASPT-------EHGIDQ-EED----GPEDASPTEHEHGVDQEED 191
Query: 305 DPTWAG-EEEGADSGEEDGADASEEDDTITNE 335
P A E G D E+ DAS + + E
Sbjct: 192 GPEDASPTEHGVDQEEDGPEDASPTEHGVDQE 223
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 52.8 bits (125), Expect = 6e-07
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 34/233 (14%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
+DQD ++ K +R R+ S+ + +LE + + S +G + K
Sbjct: 185 QDQDEDEEEKEKRGRRKASELRIH----------DLEDDLEMSSDASDASGEEGGRVPKA 234
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACE--EDGVDTSEEDP 218
KK+ K K+KK G +A + S++G+ G+ + DG +S+E+P
Sbjct: 235 KKKAPLAKGGRKKKKKKGSDDEAF---------EDSDDGDFEGQEVDYMSDGSSSSQEEP 285
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTI 278
E K ++E+G +E Q + ++ SEE+ P EED ++ EE T
Sbjct: 286 ----ESKAKAPQQEEGPKGVDE------QSDSSEESEEEKPP--EEDKEE-EEEKKAPTP 332
Query: 279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDT 331
+E R + D+ EE D+ + +++ E + S ++
Sbjct: 333 QEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNS 385
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 4/129 (3%)
Query: 208 EDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK 267
ED ++ S + +GEE + + + A ++ + +++ D + ED E +
Sbjct: 211 EDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQE 270
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASE 327
DG + +E+ E K ++E+G +E + E E EED + E
Sbjct: 271 VDYMSDGSSSSQEE----PESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326
Query: 328 EDDTITNEK 336
+ EK
Sbjct: 327 KKAPTPQEK 335
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 18/163 (11%)
Query: 174 KKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREED 233
KK A + AK A + EDS E + D SEED EED +D E++
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEED-----------DDSEED-----EEDDED--EDE 165
Query: 234 GADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDT 293
D E +A A E+D +ED D E+D + E G++ K
Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVV 225
Query: 294 REEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEK 336
+ A +ED E+E D E+D D E+D+ E+
Sbjct: 226 PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEE 268
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 51.2 bits (121), Expect = 2e-06
Identities = 78/340 (22%), Positives = 134/340 (39%), Gaps = 40/340 (11%)
Query: 17 LFPP-VPSGQGKREPQTLAVQNPPK-KVTSEKVSQKHAEPLT-DTGSETPTARRLYTASG 73
LFPP V GQ E +PPK KV S + +K LT D + P A + G
Sbjct: 53 LFPPKVDLGQNGEEKSPPNASHPPKFKVKSSPLIEKLQANLTFDPAALLPGASP--KSPG 110
Query: 74 PPEGYVPCWPEPSSCGSPENASSGDDTEDQD-PHDQPK-------------RRRIRKHKS 119
P PS+ SP S + E+ DQP R I++
Sbjct: 111 LKAMVSPFHSPPSTPSSPGVRSRPSEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPP 170
Query: 120 KKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGL 179
++F+ + E + +S Q ++ + D SK+K + + AAG
Sbjct: 171 SRRFRRSQSDCGELGDFRAVESSQQNGAKEEDGDEVLPSKSKA----PGSPLSSEGAAGE 226
Query: 180 AAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASE 239
+ G + + E EED ++ GE+ + + E DG ++
Sbjct: 227 GVRTLGPA----EKPPLRRSPSRTEKQEEDRATEEAKN----GEKARRSSEEVDGQHPAQ 278
Query: 240 EDLTRARQEEGADA-----SEEDPTPAGEE-DVKDAREEDGVDTIEEDLTRAGEEDGKDT 293
E++ + Q G +A S + PAGEE +++ A E G E++ E D ++T
Sbjct: 279 EEVPESPQTSGPEAENRCGSPREEKPAGEEAEMEKATEVKGERVQNEEV--GPEHDSQET 336
Query: 294 RE-EDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTI 332
++ E+GA E + G +G D +++ +++ +
Sbjct: 337 KKLEEGAAVKETPHSPPGGVKGGDVPKQEKGKEKQQEGAV 376
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/136 (30%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 191 QPEDSSNEGEGVGEACEEDGVDTSEED---PTLAGEEDVKDTREEDGADASEEDLTRARQ 247
+ E+ E EG GE EE+G + EE L EE+V++ + D + EED + +
Sbjct: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469
Query: 248 E-EGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDP 306
E D ++ G A+EE T+ GE+ D+ EED D E+D
Sbjct: 470 GLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLH--FLEGGEDSDSDSEEED--DEEEDD- 524
Query: 307 TWAGEEEGADSGEEDG 322
E+E D EEDG
Sbjct: 525 ----EDEDDDDDEEDG 536
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 15/133 (11%)
Query: 203 GEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEG-ADASEEDPTPA 261
GE EE+ + EE+ EE+ + EE+G + E +EEG D+ EE+
Sbjct: 405 GEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE---- 460
Query: 262 GEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTW----AGEEEGADS 317
EED + + E + + + AG G GA + PT GE+ +DS
Sbjct: 461 -EEDEESSSEGLEAEDWAQGVVEAGGSFG-----AYGAQEEAQCPTLHFLEGGEDSDSDS 514
Query: 318 GEEDGADASEEDD 330
EED + +ED+
Sbjct: 515 EEEDDEEEDDEDE 527
Score = 38.9 bits (89), Expect = 0.009
Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 26/150 (17%)
Query: 204 EACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGE 263
+A E + + G + T EE+ +EE + EE+ E
Sbjct: 373 QAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
Query: 264 EDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE--EDPTWA------------ 309
E+ EE G EE++ G+ D + EED +SE E WA
Sbjct: 433 EEEGGEGEELGE---EEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGA 489
Query: 310 -GEEEGA--------DSGEEDGADASEEDD 330
G +E A + GE+ +D+ EEDD
Sbjct: 490 YGAQEEAQCPTLHFLEGGEDSDSDSEEEDD 519
Score = 34.3 bits (77), Expect = 0.23
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 9/74 (12%)
Query: 262 GEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEED 321
GEE+ ++ EE+ EE EE+G++ EE G E EEE + G+ D
Sbjct: 405 GEEEEEEEEEEEE----EEGEGEEEEEEGEEEEEEGG-----EGEELGEEEEVEEEGDVD 455
Query: 322 GADASEEDDTITNE 335
+ EED+ ++E
Sbjct: 456 SDEEEEEDEESSSE 469
Score = 32.0 bits (71), Expect = 1.2
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query: 191 QPEDSSNEG-------EGVGEACEEDGVDTSEED---PTL----AGEEDVKDTREEDGAD 236
+ E+SS+EG +GV EA G ++E+ PTL GE+ D+ EED +
Sbjct: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
Query: 237 ASEEDLTRARQEEGADASEEDPTPA 261
+ED EE D E P P+
Sbjct: 522 EDDEDEDDDDDEEDGD---EVPVPS 543
>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 1015
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/158 (31%), Positives = 67/158 (42%), Gaps = 21/158 (13%)
Query: 192 PEDSSNEGEGVGEACE--------EDGVDTSEEDPTLAGEEDVKDTREEDGA-DASEEDL 242
PED+S GV + + E GVD E+ P A + +EEDG DAS +
Sbjct: 253 PEDASPTEHGVDQQEDGPEDASPTEHGVDQQEDGPEDARPTEHGVDQEEDGPEDASLTEH 312
Query: 243 TRARQEEGADASEEDPTPAGEEDVKDARE-----EDGVDTIEEDLTRAGEEDGKDTREED 297
+QE+G + + PT G + +D E E GVD EED G ED T E
Sbjct: 313 GVDQQEDGPE--DASPTEHGIDQEEDGPEDASPTEHGVDQ-EED----GPEDASPTEHEH 365
Query: 298 GADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
G D E+ P A E E+ DA + + E
Sbjct: 366 GVDQEEDGPEDASPTEHGVDQEDGPEDARPTEHGVDQE 403
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/201 (27%), Positives = 80/201 (39%), Gaps = 33/201 (16%)
Query: 192 PEDSSNEGEGVGEACE--------EDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLT 243
PED+S GV + + E G+D E+ P A + +EEDG ED +
Sbjct: 304 PEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHGVDQEEDGP----EDAS 359
Query: 244 RARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE 303
E G D E+ P A E GVD +ED G ED + T E G D +
Sbjct: 360 PTEHEHGVDQEEDGPEDASPT-------EHGVD--QED----GPEDARPT--EHGVDQED 404
Query: 304 EDPTWAGEEEGADSGEEDGA-DASEEDDTITNEKAHSILNFLKSTQE---MYFYDGVSRD 359
E G D +EDG DAS + + + + FL S ++ + F S
Sbjct: 405 GPEDARPTEHGVD--QEDGPEDASRTEHGVGHRAGRACAAFLSSRRDNLYLSFKKANSAH 462
Query: 360 AASAALADAAEELLDRLASHS 380
+ + ELLD + H+
Sbjct: 463 VTGIISSRSDSELLDWNSKHT 483
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/225 (21%), Positives = 91/225 (40%), Gaps = 21/225 (9%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
E++ + +R + +H +KF+ +L E E+QQ QE+ ++ + + +
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG---EEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 161 KKRK--LKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
++ + L+++QQ++R++ E E E + + E++ + E
Sbjct: 1704 ERERKFLQEEQQLRRQEL----------------ERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTI 278
+ EE ++ REE E D +E+ EE + E D K EE
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
Query: 279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGA 323
EE R + DGK EE+ E++ E + EE A
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852
Score = 48.9 bits (115), Expect = 9e-06
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 22/224 (9%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
E+Q ++P++R R+ + +KK++ E+ + E++Q L +E+ +R+ + +
Sbjct: 970 EEQLLGEEPEKR--RRQEREKKYREE-----EELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACE-----------ED 209
K ++++Q+ R++ + + + E E + +GE E
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 210 GVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+ +E+ L EE K R+E EE+ +QEE EE +E +
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEE--ELQQEEEQLLREEREKRRRQELERQY 1140
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEE 313
REE+ V EE L R EE K R+E EE+ EE+
Sbjct: 1141 REEEEVQQEEEQLLR--EEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 46.6 bits (109), Expect = 5e-05
Identities = 48/231 (20%), Positives = 96/231 (41%), Gaps = 13/231 (5%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
ED+ + + +++ + + +KF L Q E++Q L ++ ++ + + +
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ---EREQQLRHDRDRKFREEEQLLQEG 1679
Query: 161 KKRKLKKKQQIK--RKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
++++L+++++ + R++ L + F+ Q E E + EE+ + E
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFL-QEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTI 278
L +E + EE E L R+E+ E D EE ++ REE + +
Sbjct: 1739 QLRRQERYRKILEE-------EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
E D EE + REE + D + EEE E++ E D
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/263 (20%), Positives = 100/263 (38%), Gaps = 27/263 (10%)
Query: 101 EDQDPHDQPKRRRIRKHKSK------KKFKNPNNVLIEQAE------------LEKQQSL 142
E+Q Q + R+ + + + +KF+ +L E+ E LE++Q L
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 143 LQEKSQRQHTDGTTISKNKKRK-LKKKQQIKRKKAAG--------LAAKAAGVSFMYQPE 193
+++ R+ + S+ +RK L+++QQ+ R++ L + G +
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 194 DSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADA 253
E E + + EE + E D EE +E++ +E R ++ +
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 254 SEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEE 313
E D +E + REE + E D EE +E + + D + EE+
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 314 GADSGEEDGADASEEDDTITNEK 336
GEE E D E+
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEE 1697
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/203 (21%), Positives = 92/203 (45%), Gaps = 14/203 (6%)
Query: 110 KRRRIRKHKSKKKFKNPNNVLIEQAEL---EKQQSLLQEKSQRQHTDGTTISKNKK---- 162
+R + R+ + +++++ + + E+ +L E+++ LQE+ +RQ+ + + + ++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER-ERQYREEEELQQEEEQLLG 1065
Query: 163 --RKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTL 220
R+ +++Q+++R+ + + + + E + EE+ + EE L
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ--L 1123
Query: 221 AGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEE 280
EE K R+E EE+ +QEE EE +E + REE+ + EE
Sbjct: 1124 LREEREKRRRQELERQYREEE--EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE 1181
Query: 281 DLTRAGEEDGKDTREEDGADASE 303
L R +E + RE + E
Sbjct: 1182 QLLREEQEKRRQERERQYREEEE 1204
Score = 43.1 bits (100), Expect = 5e-04
Identities = 48/243 (19%), Positives = 96/243 (39%), Gaps = 8/243 (3%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAEL-----EKQQSLLQEKSQ-RQHTDG 154
++Q Q ++++R+ + +K F+ +L E+ E E+ + L+E+ Q R+
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRK-FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658
Query: 155 TTISKNKKRKLKKKQQIKRK-KAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDT 213
+ ++ RK ++++Q+ ++ + L + F + + + EE +
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRR 1718
Query: 214 SEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREED 273
E + EE ++ E++ E +E+ EE E D K EE
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 274 GVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTIT 333
EE R+ E D K EE EE + +G EE+ E++ +
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 334 NEK 336
E+
Sbjct: 1839 QER 1841
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/227 (20%), Positives = 98/227 (43%), Gaps = 24/227 (10%)
Query: 99 DTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTIS 158
+ E++ ++ ++R R+ + +++++ EQ + E++Q L +E+ +R+ +
Sbjct: 908 EEEEELQREEREKR--RRQEQERQYREE-----EQLQQEEEQLLREEREKRRRQERERQY 960
Query: 159 KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVD------ 212
+ K+ +K++Q+ ++ + + + E E + + E E+
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 213 ------TSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDV 266
EE+ L E + + +E + EE+L +QEE EE T +E
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEEL---QQEEEQLLGEERETRRRQELE 1077
Query: 267 KDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEE 313
+ R+E+ + EE L R EE K R+E EE+ EE+
Sbjct: 1078 RQYRKEEELQQEEEQLLR--EEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 39.3 bits (90), Expect = 0.007
Identities = 43/229 (18%), Positives = 96/229 (41%), Gaps = 6/229 (2%)
Query: 102 DQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQS-LLQEKSQRQHTDGTTISKN 160
+++ Q + + +R+ K++ + E+ EL++++ LL+E+ +++ + +
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE----RER 1197
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPE-DSSNEGEGVGEACEEDGVDTSEEDPT 219
+ R+ ++ Q+ KRK+ + + + + ++PE +++ V E+ ED
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 220 LAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE 279
L + +D + G + R+ + D + E+ K+A+ D E
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 280 EDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEE 328
+ L R E+ + +E D EE EE+ E D EE
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Score = 39.3 bits (90), Expect = 0.007
Identities = 46/207 (22%), Positives = 90/207 (43%), Gaps = 11/207 (5%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQ--RQHTDGTTIS 158
E++ + + +++R+ + +KF+ L Q E+++ LQE+ Q RQ +
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ---ERERKFLQEEQQLRRQELERKFRE 1727
Query: 159 KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
+ + R+ +++Q++R++ + + + E E + EE+ + E+
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLR-PEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 219 TLAGEEDVKDTREEDG-ADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDT 277
L +E + REE+ EE R +Q +G EE+ E++ + +E D
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR 1846
Query: 278 IEEDLTRAGEEDGKDTREEDGADASEE 304
EE A +E K REE EE
Sbjct: 1847 AEEQF--ATQE--KSRREEQELWQEEE 1869
Score = 37.4 bits (85), Expect = 0.028
Identities = 44/219 (20%), Positives = 86/219 (39%), Gaps = 14/219 (6%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
E+Q ++ K + R KS+++ +L E+ E ++++ QE ++ + + +
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEE----KQLLREEREEKRRR---QETDRKFREEEQLLQER 1348
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTL 220
+++ L+++++ ++ + L + G F+ + + + EE + E + L
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 221 AGEEDVKDTREEDGADASE-------EDLTRARQEEGADASEEDPTPAGEEDVKDAREED 273
+ D K EE E E+ RQE EE+ E K EE
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 274 GVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEE 312
+ EE E D K EE E D + +E
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Score = 37.4 bits (85), Expect = 0.028
Identities = 46/242 (19%), Positives = 96/242 (39%), Gaps = 8/242 (3%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQA--ELEKQQSLLQEKSQRQHTDGTTIS 158
+++D + + +++R+ + ++KF L ++ + +++ LLQE+ ++Q
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ----LHRQ 1481
Query: 159 KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
+ ++ L+++QQ++R++ + S +PE E E + EE
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRS--QEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTI 278
E + ++ D EE L + R+E+ E D EE +E++
Sbjct: 1540 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAH 338
+E R E + +E D +E EE+ E D EE E+
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Query: 339 SI 340
+
Sbjct: 1660 QL 1661
Score = 36.2 bits (82), Expect = 0.061
Identities = 54/235 (22%), Positives = 94/235 (40%), Gaps = 40/235 (17%)
Query: 105 PHDQPKRRRIRKHKSKKKFKNPNNVLIEQAEL---EKQQSLLQEKSQRQHTDGTTISKNK 161
P ++ K +R R+ + ++K L E+ +L E+ Q L +E+ Q S+ +
Sbjct: 812 PEEEEKEQRRRQRREREK---ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 162 KRKLKKKQQI---KRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
+R K + Q+ ++++ L AK A + + + E EE+ + E +
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE--------EEEELQREEREK 920
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRA--------------------RQEEGADASEEDP 258
E++ + REE+ EE L R +Q+E EE
Sbjct: 921 RRRQEQE-RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 259 TPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEE 313
+E K REE+ + EE L R EE K R+E ++D EE+
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLR--EEREKRRRQEWERQYRKKDELQQEEEQ 1032
Score = 36.2 bits (82), Expect = 0.061
Identities = 55/262 (20%), Positives = 101/262 (38%), Gaps = 22/262 (8%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQ---SLLQEKSQ-RQHTDGTT 156
E+Q Q + R+ R+ + + + + L E+ +L +QQ LQE+ Q R+ G
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 157 ISKNKKRKLKKKQQIKRKKAAG-LAAKAAGVSF---------------MYQPEDSSNEGE 200
+++ RK ++++Q+++++ L+ + F + E E
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 201 GVGEACEEDGVDTSEEDPTLAGEEDVKDTREE-DGADASEEDLTRARQEEGADASEEDPT 259
G + +E E++ L E+ + R+E D EE R ++ E + D
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 260 PAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGE 319
EE + EE + E D EE +E + EE E E E
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 320 EDGADASEEDDTITNEKAHSIL 341
E +E++ E+ IL
Sbjct: 1729 EQLRQETEQEQLRRQERYRKIL 1750
Score = 35.4 bits (80), Expect = 0.10
Identities = 45/248 (18%), Positives = 100/248 (40%), Gaps = 5/248 (2%)
Query: 92 ENASSGDDTEDQD-PHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQ 150
E++ D QD H +++ + + +++++ + E+ +LE+++ ++ R+
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 151 HTDGTTISKNKKRKLKKKQQIKRK--KAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEE 208
+ + + ++ + +++Q+ RK + L + Q D E + +E
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH--QE 1371
Query: 209 DGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKD 268
G EE+ L +E + +E+ +E + RQ+ EE+ + +E +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK 1431
Query: 269 AREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEE 328
REE+ +E + EE+ + +E EE EE+ E D EE
Sbjct: 1432 FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491
Query: 329 DDTITNEK 336
E+
Sbjct: 1492 QQLRRQER 1499
Score = 33.9 bits (76), Expect = 0.30
Identities = 46/246 (18%), Positives = 96/246 (39%), Gaps = 17/246 (6%)
Query: 109 PKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKK 168
P+ ++ + + K+ + E+ L +++ +EK +RQ TD + + + +++
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREER---EEKRRRQETDRKFREEEQLLQEREE 1350
Query: 169 QQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKD 228
Q ++R++ ++ E+ ++ +G EE + E + EE
Sbjct: 1351 QPLRRQER----------DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 229 TREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEE 288
+E + + D + R+EE + +E EE+ + R+E +EE+ E
Sbjct: 1401 CQEREQQLRQDRD-RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 289 DGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHS---ILNFLK 345
K EE EE E + EE E D ++ S FL+
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 346 STQEMY 351
Q+++
Sbjct: 1520 EEQQLH 1525
Score = 32.3 bits (72), Expect = 0.89
Identities = 29/164 (17%), Positives = 72/164 (43%), Gaps = 31/164 (18%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVL------IEQAELEKQQSLLQEKSQRQHTDG 154
E++ + ++ R+ + + +K+++ VL +++ E ++Q+ L +E+ Q + +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 155 TTISKNKK------RKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEE 208
+ + ++ ++L+++QQ++RK Q E+ + E E E
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRK----------------QEEERREQQEERREQQER 327
Query: 209 DGVDTSEEDPTLAGEEDVK---DTREEDGADASEEDLTRARQEE 249
+ L E++ + R E + E+ L R ++EE
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Score = 32.3 bits (72), Expect = 0.89
Identities = 36/190 (18%), Positives = 81/190 (42%), Gaps = 19/190 (10%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
++++ +Q RR + + +++ + + EQ +L ++Q L +E+ R+
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQ-----LR 408
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEED-GVDTSEEDPT 219
++++L+++QQ++R++ + E+ +E + E E+ + E
Sbjct: 409 REQQLRREQQLRREQ-----------QLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 220 LAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIE 279
L EE+ + +E + D R+E EE+ E + R E + E
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ-EERRE 516
Query: 280 EDLTRAGEED 289
+ L R EE+
Sbjct: 517 QRLKRQEEEE 526
Score = 32.3 bits (72), Expect = 0.89
Identities = 42/201 (20%), Positives = 83/201 (41%), Gaps = 9/201 (4%)
Query: 103 QDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNKK 162
Q ++ +R + ++++K + L + L +Q+ +RQ + + + ++
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 163 RKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAG 222
++ +++Q+ +R+K + + + + E +G+ E E D
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 223 --EEDVKDTREEDGA-DASEEDLTRARQ----EEGADASEEDPTPAGEEDVKDAREEDGV 275
EE+ K R A A +E L + +Q EE EE +E + REE+ +
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 276 DTIEEDLTRAGEEDGKDTREE 296
EE L R EE K R+E
Sbjct: 937 QQEEEQLLR--EEREKRRRQE 955
Score = 30.8 bits (68), Expect = 2.6
Identities = 42/245 (17%), Positives = 96/245 (39%), Gaps = 13/245 (5%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
E+ + H+Q +R++ K +++ + L E+ E+Q+ Q+ + Q K
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTL 220
++ + + +Q+++ ++ + + + E+ E E + + + D L
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE--QEERRDQLL 579
Query: 221 AGEEDVKDTR----EEDGAD--ASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDG 274
EE+ + R +E+ + E++ R QEE + + P E + + E+
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 275 VDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITN 334
+ ++ L R +E R E EE+ + E + +EE+
Sbjct: 640 EERRQQQLRREQQE-----RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 335 EKAHS 339
E+ S
Sbjct: 695 ERIKS 699
Score = 29.6 bits (65), Expect = 5.7
Identities = 15/77 (19%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQR--QHTDGTTIS 158
E++ Q +RR ++ + +++ + + EQ E +QQ +++ +R Q
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 159 KNKKRKLKKKQQIKRKK 175
+ ++++L+++QQ++R++
Sbjct: 371 ERREQQLRREQQLRREQ 387
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 50.8 bits (120), Expect = 2e-06
Identities = 60/255 (23%), Positives = 98/255 (38%), Gaps = 20/255 (7%)
Query: 85 PSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQ 144
P SPE A + D + + R K +K K+P V E EK +S L+
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP--VKEEVKSPEKAKSPLK 804
Query: 145 EKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGE 204
E + K ++++ KK+++K K V P+ + E
Sbjct: 805 EDA-----------KAPEKEIPKKEEVKSPVKE--EEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 205 ACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEE 264
EE EE P + + ++E + +E A++EE D ++ PTP E
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED-KKKVPTPEKEA 910
Query: 265 DVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG-EEEGADSGEE--- 320
K +ED + ++ + +D K A+ E P +EE A EE
Sbjct: 911 PAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPK 970
Query: 321 DGADASEEDDTITNE 335
A A E+D T++ E
Sbjct: 971 TEAKAKEDDKTLSKE 985
Score = 47.4 bits (111), Expect = 3e-05
Identities = 76/325 (23%), Positives = 126/325 (38%), Gaps = 32/325 (9%)
Query: 19 PPVPSGQGKREPQTLAVQNPPKKVTS--EKVSQKHAEPLTDTGSETPTARRLYTASGPPE 76
PP K E ++ A P+K S ++ ++ AE + +++P A P E
Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE---AKSPAE 617
Query: 77 GYVPCWPE---PSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQ 133
P E P+ SPE A S E + P ++ K + KS +K K+P V E
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP-EKAKSPEKEEAKSPEKAKSP--VKAEA 674
Query: 134 AELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPE 193
EK +S ++ +++ + + + K K K +K + + AK+ PE
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 194 DSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQE--EGA 251
+ + + EE + P A DVK S E T A++E A
Sbjct: 735 KAKSPVK------EEAKSPEKAKSPEKAKTLDVK----------SPEAKTPAKEEARSPA 778
Query: 252 DASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGE 311
D E +E+VK E ++ED +A E++ E EE P
Sbjct: 779 DKFPEKAKSPVKEEVKSP--EKAKSPLKED-AKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835
Query: 312 EEGADSGEEDGADASEEDDTITNEK 336
+E EE+ A A+ + + + K
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSK 860
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 7/132 (5%)
Query: 211 VDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGAD--ASEEDPTPAGEEDVKD 268
V+ SE++ T+ EE ++T+ + + +EE+ A++EEG + EE+ GEE+ K
Sbjct: 447 VEKSEKE-TVIVEEQTEETQVTE--EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKS 503
Query: 269 AREEDGVDTIEEDLTRAGEEDGKDTREEDGADASE-EDPTWAGEEEGADSGEEDGADASE 327
E+ E++ +E+ K E + E + P E A S ++ A +
Sbjct: 504 PPAEEAASP-EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562
Query: 328 EDDTITNEKAHS 339
E + E+A S
Sbjct: 563 EAKSPEKEEAKS 574
Score = 37.4 bits (85), Expect = 0.028
Identities = 38/194 (19%), Positives = 70/194 (36%), Gaps = 25/194 (12%)
Query: 84 EPSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLL 143
EP E A + TE++ D K +K K K + +E+ + K ++
Sbjct: 837 EPPKKAEEEKAPATPKTEEKK--DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 144 QEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVG 203
+E ++ T K K++ K+ K K+ +A K + +P + + E
Sbjct: 895 EEAEDKKKVP--TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 204 EACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGE 263
E KDT+EE E+ T A+ +E ++P+
Sbjct: 953 EK---------------------KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Query: 264 EDVKDAREEDGVDT 277
E + + D D+
Sbjct: 992 EKAEKSSSTDQKDS 1005
Score = 35.4 bits (80), Expect = 0.10
Identities = 55/306 (17%), Positives = 108/306 (35%), Gaps = 15/306 (4%)
Query: 27 KREPQTLAV--QNPPKKVTSEKVSQKHAEPLTDTGSETPTARRLYTASGPPEGYVPCWPE 84
K E +T+ V Q +VT E ++ E + G E G E P E
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 85 PSSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQ 144
SPE + E+ + K + KS + K+P E K +
Sbjct: 509 ---AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 145 EKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGE 204
+ + + +K K K++ K A KA E++ + E
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP----VKEEAKSPAEAKSP 621
Query: 205 ACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTP-AGE 263
EE + P A ++ + + A + E++ ++ ++ + E +P +
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 264 EDVK-DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDG 322
VK +A+ + + ++ ++ E+ +EE + + P +E A + E+
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV----KEEAKTPEKAK 737
Query: 323 ADASEE 328
+ EE
Sbjct: 738 SPVKEE 743
Score = 35.0 bits (79), Expect = 0.14
Identities = 28/138 (20%), Positives = 57/138 (41%), Gaps = 2/138 (1%)
Query: 204 EACEEDGVDTS--EEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPA 261
EA EE+G + EE+ GEE+ K E+ A +E + ++E + A + P
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 262 GEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEED 321
+ + + + + ++ ++ E +EE + A + P A ++
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 322 GADASEEDDTITNEKAHS 339
A + E+ + E+A S
Sbjct: 597 EAKSPEKAKSPVKEEAKS 614
Score = 32.7 bits (73), Expect = 0.68
Identities = 45/241 (18%), Positives = 95/241 (39%), Gaps = 15/241 (6%)
Query: 105 PHDQPKRRRIRKH---KSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKNK 161
P PK + H KS++K K ++E++E K+ +++E Q + T T +
Sbjct: 423 PEGLPKIPSVSTHIKVKSEEKIK-----VVEKSE--KETVIVEE--QTEETQVTEEVTEE 473
Query: 162 KRKLKKKQQIKRKKAAGLAAKAAGVSFMYQP---EDSSNEGEGVGEACEEDGVDTSEEDP 218
+ K K+++ K ++ G P E +S E E EE + P
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 219 TLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTI 278
+ + + + A + ++ ++ E + EE +PA + + A+ +
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAH 338
++ E+ +EE + A + P + A+ + A + +++ + EKA
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 339 S 339
S
Sbjct: 654 S 654
Score = 32.0 bits (71), Expect = 1.2
Identities = 31/165 (18%), Positives = 60/165 (36%), Gaps = 15/165 (9%)
Query: 27 KREPQTLAVQNPPKKVTSEKV-----------SQKHAEPLTDTGSETPTARRLYTASGPP 75
+ +PQ + V+ PPKK EK S+K P + ++ P
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 76 EGYVPCWPEPS----SCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLI 131
E V E + +PE + +D + K +K K K P+
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE 946
Query: 132 EQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKA 176
++ +++ +EK+++ T +K K+ ++ + KA
Sbjct: 947 KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Score = 31.2 bits (69), Expect = 2.0
Identities = 32/147 (21%), Positives = 55/147 (37%), Gaps = 16/147 (10%)
Query: 20 PVPSGQGKREPQTLAVQNPPK-KVTSEKVSQKHAEPLTDTGSETPTARRLYTASGPPEGY 78
P P + K+EP AV+ P + KV ++K + + + E P + + P E
Sbjct: 870 PKPKVEEKKEP---AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Query: 79 VPCWPEPSSCGSPENASSGD---------DTEDQD---PHDQPKRRRIRKHKSKKKFKNP 126
EP + E + + DT+++ P ++PK K K K P
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 127 NNVLIEQAELEKQQSLLQEKSQRQHTD 153
+ E+AE K + T+
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATE 1013
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 86 SSCGSPENASSGDDTEDQDPHDQPKRRRIRKHKSKK------KFKNPNNVLIEQAELEKQ 139
SS S AS D E + D+ +R R R+ K ++ K K + E EK+
Sbjct: 544 SSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKE 603
Query: 140 QSLLQEKSQRQHTDG----TTISKNKKRKLKKKQQIKRKKAAGLAAKAAG-------VSF 188
+ ++K + +H DG I K K +LKK Q+ +++ L + V
Sbjct: 604 RDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQL 663
Query: 189 MYQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTRE-EDGADASEEDLTRARQ 247
M + S E E + + ++ +E+ +A E+ ++ R E+ + ++ L A+Q
Sbjct: 664 MAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQ 723
Query: 248 EEGADASEEDPTPAGEEDVKD 268
EE A SE D T ED+++
Sbjct: 724 EEEALLSEMDVTGQAFEDMQE 744
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 49.3 bits (116), Expect = 7e-06
Identities = 59/274 (21%), Positives = 114/274 (41%), Gaps = 22/274 (8%)
Query: 116 KHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQ---HTDGTTISKNKKR--KLKKKQQ 170
K KSK + ++ + + + K SLL+++ + D +T K KK K K ++
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKP 1160
Query: 171 IKRKKAAGLAAKAAGVSFMYQPEDSSNEG------EGVGEACEEDGVDTSEEDPTLAGEE 224
I KK G + G + S + + +A + + SEE T+ +E
Sbjct: 1161 IHWKKRPG---RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEE--TVEPKE 1215
Query: 225 DV---KDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEED 281
D+ ++ +EE+ A E+ +E+ A + +PA + + ++ EE+
Sbjct: 1216 DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE 1275
Query: 282 LTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSIL 341
R EE + EE+ + E +P E+ A++ + D DA +EDD L
Sbjct: 1276 KPRVSEEQRQS--EEEQQELEEPEPE-EEEDAAAETAQNDDHDADDEDDGHLESTKKKEL 1332
Query: 342 NFLKSTQEMYFYDGVSRDAASAALADAAEELLDR 375
+ +++ GV A + + E++ D+
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDK 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/249 (19%), Positives = 104/249 (41%), Gaps = 12/249 (4%)
Query: 90 SPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQR 149
SP ++S+ +TE ++P + + + R + +++ + L E+ E E+++ E +Q
Sbjct: 1253 SPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL-EEPEPEEEEDAAAETAQN 1311
Query: 150 QHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEED 209
D KKK +++ + + GV + + E + + EE
Sbjct: 1312 DDHDADDEDDGHLESTKKK-ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDK-EET 1369
Query: 210 GVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+D+ EE P+ D E+ + + +EE + EE+ P E D++
Sbjct: 1370 ELDSEEEQPS----HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
+ V ++ ++ + E +D E A + + T A E+ E+ ASE +
Sbjct: 1426 Q---AVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVED--CHASEHN 1480
Query: 330 DTITNEKAH 338
I++ ++H
Sbjct: 1481 SPISSVQSH 1489
Score = 42.7 bits (99), Expect = 7e-04
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFM--YQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
++RK +++ Q + ++A + A S + P DSSN E +E V+ EE P
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE---TETKEPEVEEEEEKP 1277
Query: 219 TLAGE----EDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK------- 267
++ E E+ + EE + E+ Q + DA +ED K
Sbjct: 1278 RVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPT 1337
Query: 268 --DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADA 325
D +EE GV D + +EE D+ EE P+ + S + G++
Sbjct: 1338 REDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS---HDTSVVSEQMAGSED 1394
Query: 326 SEEDDTITNEK 336
E+D+ T E+
Sbjct: 1395 DHEEDSHTKEE 1405
Score = 33.5 bits (75), Expect = 0.40
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 127 NNVLIEQAELEKQQSLLQEKSQRQH----TDGTTISKNKKRKLKKKQQIKRKKAAGLAAK 182
N+V+ E+ E E ++ +E ++ + G ++S K + + ++K
Sbjct: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
Query: 183 AAGVSFMYQPEDS-------SNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDG- 234
+ +S P DS S G G + ++D L EE +E+ G
Sbjct: 843 STRLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGE 901
Query: 235 ----ADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGE 287
++A++E T + EE ASEE P+ G+ D+ R +GV+ L ++ E
Sbjct: 902 CGEKSEATQEQYTES--EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 49.3 bits (116), Expect = 7e-06
Identities = 59/274 (21%), Positives = 114/274 (41%), Gaps = 22/274 (8%)
Query: 116 KHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQ---HTDGTTISKNKKR--KLKKKQQ 170
K KSK + ++ + + + K SLL+++ + D +T K KK K K ++
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKP 1160
Query: 171 IKRKKAAGLAAKAAGVSFMYQPEDSSNEG------EGVGEACEEDGVDTSEEDPTLAGEE 224
I KK G + G + S + + +A + + SEE T+ +E
Sbjct: 1161 IHWKKRPG---RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEE--TVEPKE 1215
Query: 225 DV---KDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEED 281
D+ ++ +EE+ A E+ +E+ A + +PA + + ++ EE+
Sbjct: 1216 DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE 1275
Query: 282 LTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSIL 341
R EE + EE+ + E +P E+ A++ + D DA +EDD L
Sbjct: 1276 KPRVSEEQRQS--EEEQQELEEPEPE-EEEDAAAETAQNDDHDADDEDDGHLESTKKKEL 1332
Query: 342 NFLKSTQEMYFYDGVSRDAASAALADAAEELLDR 375
+ +++ GV A + + E++ D+
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDK 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/249 (19%), Positives = 104/249 (41%), Gaps = 12/249 (4%)
Query: 90 SPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQR 149
SP ++S+ +TE ++P + + + R + +++ + L E+ E E+++ E +Q
Sbjct: 1253 SPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL-EEPEPEEEEDAAAETAQN 1311
Query: 150 QHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEED 209
D KKK +++ + + GV + + E + + EE
Sbjct: 1312 DDHDADDEDDGHLESTKKK-ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDK-EET 1369
Query: 210 GVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+D+ EE P+ D E+ + + +EE + EE+ P E D++
Sbjct: 1370 ELDSEEEQPS----HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
+ V ++ ++ + E +D E A + + T A E+ E+ ASE +
Sbjct: 1426 Q---AVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVED--CHASEHN 1480
Query: 330 DTITNEKAH 338
I++ ++H
Sbjct: 1481 SPISSVQSH 1489
Score = 42.7 bits (99), Expect = 7e-04
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFM--YQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
++RK +++ Q + ++A + A S + P DSSN E +E V+ EE P
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE---TETKEPEVEEEEEKP 1277
Query: 219 TLAGE----EDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK------- 267
++ E E+ + EE + E+ Q + DA +ED K
Sbjct: 1278 RVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPT 1337
Query: 268 --DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADA 325
D +EE GV D + +EE D+ EE P+ + S + G++
Sbjct: 1338 REDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS---HDTSVVSEQMAGSED 1394
Query: 326 SEEDDTITNEK 336
E+D+ T E+
Sbjct: 1395 DHEEDSHTKEE 1405
Score = 33.5 bits (75), Expect = 0.40
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 127 NNVLIEQAELEKQQSLLQEKSQRQH----TDGTTISKNKKRKLKKKQQIKRKKAAGLAAK 182
N+V+ E+ E E ++ +E ++ + G ++S K + + ++K
Sbjct: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
Query: 183 AAGVSFMYQPEDS-------SNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDG- 234
+ +S P DS S G G + ++D L EE +E+ G
Sbjct: 843 STRLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGE 901
Query: 235 ----ADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGE 287
++A++E T + EE ASEE P+ G+ D+ R +GV+ L ++ E
Sbjct: 902 CGEKSEATQEQYTES--EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 49.3 bits (116), Expect = 7e-06
Identities = 59/274 (21%), Positives = 114/274 (41%), Gaps = 22/274 (8%)
Query: 116 KHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQ---HTDGTTISKNKKR--KLKKKQQ 170
K KSK + ++ + + + K SLL+++ + D +T K KK K K ++
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKP 1160
Query: 171 IKRKKAAGLAAKAAGVSFMYQPEDSSNEG------EGVGEACEEDGVDTSEEDPTLAGEE 224
I KK G + G + S + + +A + + SEE T+ +E
Sbjct: 1161 IHWKKRPG---RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQESEE--TVEPKE 1215
Query: 225 DV---KDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEED 281
D+ ++ +EE+ A E+ +E+ A + +PA + + ++ EE+
Sbjct: 1216 DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEE 1275
Query: 282 LTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSIL 341
R EE + EE+ + E +P E+ A++ + D DA +EDD L
Sbjct: 1276 KPRVSEEQRQS--EEEQQELEEPEPE-EEEDAAAETAQNDDHDADDEDDGHLESTKKKEL 1332
Query: 342 NFLKSTQEMYFYDGVSRDAASAALADAAEELLDR 375
+ +++ GV A + + E++ D+
Sbjct: 1333 EEQPTREDVKEEPGVQESFLDANMQKSREKIKDK 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/249 (19%), Positives = 104/249 (41%), Gaps = 12/249 (4%)
Query: 90 SPENASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQR 149
SP ++S+ +TE ++P + + + R + +++ + L E+ E E+++ E +Q
Sbjct: 1253 SPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL-EEPEPEEEEDAAAETAQN 1311
Query: 150 QHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEED 209
D KKK +++ + + GV + + E + + EE
Sbjct: 1312 DDHDADDEDDGHLESTKKK-ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDK-EET 1369
Query: 210 GVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDA 269
+D+ EE P+ D E+ + + +EE + EE+ P E D++
Sbjct: 1370 ELDSEEEQPS----HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETV 1425
Query: 270 REEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEED 329
+ V ++ ++ + E +D E A + + T A E+ E+ ASE +
Sbjct: 1426 Q---AVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVED--CHASEHN 1480
Query: 330 DTITNEKAH 338
I++ ++H
Sbjct: 1481 SPISSVQSH 1489
Score = 42.7 bits (99), Expect = 7e-04
Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 21/191 (10%)
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFM--YQPEDSSNEGEGVGEACEEDGVDTSEEDP 218
++RK +++ Q + ++A + A S + P DSSN E +E V+ EE P
Sbjct: 1221 EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPE---TETKEPEVEEEEEKP 1277
Query: 219 TLAGE----EDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK------- 267
++ E E+ + EE + E+ Q + DA +ED K
Sbjct: 1278 RVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPT 1337
Query: 268 --DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADA 325
D +EE GV D + +EE D+ EE P+ + S + G++
Sbjct: 1338 REDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS---HDTSVVSEQMAGSED 1394
Query: 326 SEEDDTITNEK 336
E+D+ T E+
Sbjct: 1395 DHEEDSHTKEE 1405
Score = 33.5 bits (75), Expect = 0.40
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 19/177 (10%)
Query: 127 NNVLIEQAELEKQQSLLQEKSQRQH----TDGTTISKNKKRKLKKKQQIKRKKAAGLAAK 182
N+V+ E+ E E ++ +E ++ + G ++S K + + ++K
Sbjct: 783 NSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVS 842
Query: 183 AAGVSFMYQPEDS-------SNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDG- 234
+ +S P DS S G G + ++D L EE +E+ G
Sbjct: 843 STRLSKQVLPHDSLPANSQPSRRGRW-GRKNRKTQERFGDKDSKLLLEETSSAPQEQYGE 901
Query: 235 ----ADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGE 287
++A++E T + EE ASEE P+ G+ D+ R +GV+ L ++ E
Sbjct: 902 CGEKSEATQEQYTES--EEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPE 956
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 48.9 bits (115), Expect = 9e-06
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 14/137 (10%)
Query: 211 VDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEED----PTPAGEEDV 266
VD + E+ EEDV+ + D E+ +E+ DA + P PA EE V
Sbjct: 242 VDDNNEE-----EEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAV 296
Query: 267 KDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG---EEEGADSGEEDGA 323
+D ++ED +E++T+ GE R++D D E D T E E S E
Sbjct: 297 EDCKDEDFAK--DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEE 354
Query: 324 DASEEDDTITNEKAHSI 340
+S ++D + E+ I
Sbjct: 355 LSSNQEDAVIVEQPEVI 371
>gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens]
Length = 213
Score = 48.9 bits (115), Expect = 9e-06
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 14/137 (10%)
Query: 211 VDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEED----PTPAGEEDV 266
VD + E+ EEDV+ + D E+ +E+ DA + P PA EE V
Sbjct: 7 VDDNNEE-----EEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAV 61
Query: 267 KDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG---EEEGADSGEEDGA 323
+D ++ED +E++T+ GE R++D D E D T E E S E
Sbjct: 62 EDCKDEDFAK--DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEE 119
Query: 324 DASEEDDTITNEKAHSI 340
+S ++D + E+ I
Sbjct: 120 LSSNQEDAVIVEQPEVI 136
Score = 34.7 bits (78), Expect = 0.18
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 198 EGEGVGEACEEDGVDTSEEDPTLAGEEDV----KDTREEDGADASEEDLTRAR-QEEGAD 252
E E E + + +++ED + + +V +D E++G A ED R + EG+
Sbjct: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
Query: 253 ASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEED 289
E P P E + + + D ++ +ED AG +D
Sbjct: 167 DLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQD 203
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 48.9 bits (115), Expect = 9e-06
Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 28/132 (21%)
Query: 190 YQPEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEE 249
Y ED E E DGVD EED E+ +D +ED D EE+ E+
Sbjct: 148 YDREDQ----EAPDSDAEVDGVDEEEED------EEGEDEEDEDDEDGEEEEFDEEDDED 197
Query: 250 GADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWA 309
+ED +++V + EE G+D EED E++ +D EE+G +
Sbjct: 198 EDVEGDED-----DDEVSEEEEEFGLD--EED-----EDEDEDEEEEEGGKGEKR----- 240
Query: 310 GEEEGADSGEED 321
+ E D GE+D
Sbjct: 241 -KRETDDEGEDD 251
Score = 46.2 bits (108), Expect = 6e-05
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 12/105 (11%)
Query: 233 DGADASEEDLTRARQE-EGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGK 291
DG D +++ + E +G D EED E+ +D +ED D EE+ +ED
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEED------EEGEDEEDEDDEDGEEEEFDEEDDEDED 199
Query: 292 DTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEK 336
+ED + SEE+ EE G D +ED + EE++ EK
Sbjct: 200 VEGDEDDDEVSEEE-----EEFGLDEEDEDEDEDEEEEEGGKGEK 239
Score = 43.5 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 230 REEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEED 289
RE+ A S+ ++ +EE + E++ +ED +D EE+ + +ED G+ED
Sbjct: 150 REDQEAPDSDAEVDGVDEEEEDEEGEDEE----DEDDEDGEEEEFDEEDDEDEDVEGDED 205
Query: 290 GKDTREED---GADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
+ EE+ G D +ED EEE GE+ + +E +
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGE 249
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 48.9 bits (115), Expect = 9e-06
Identities = 62/261 (23%), Positives = 102/261 (39%), Gaps = 41/261 (15%)
Query: 98 DDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTI 157
DDT+D P + K+RR + S+++ ++ E E +K++ K + D T
Sbjct: 923 DDTDDDLPISKKKKRR-KGSGSEQEGEDE-----EGGERKKKKRRRHPKGEEGSDDDETE 976
Query: 158 S--KNKKRKLKKKQQIKRKKAAGLAAKAAGV----SFMYQPEDSSNE--------GEGVG 203
+ K KKR+ K ++ K K L G + + +DSS+E G
Sbjct: 977 NGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRN 1036
Query: 204 EACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPT---- 259
D + + + E D + + + G++A R RQ D+ + P+
Sbjct: 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPR-RQRSDQDSDSDQPSRKRR 1095
Query: 260 PAGEED-----VKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGAD--------ASEEDP 306
P+G E V+ R GV E D A D E G+D +E +P
Sbjct: 1096 PSGSEQSDNESVQSGRSHSGVS--ENDSRPASPSAESDHESERGSDNEGSGQGSGNESEP 1153
Query: 307 TWAGEEEGADSGEEDGADASE 327
E +D G E G+D S+
Sbjct: 1154 E-GSNNEASDRGSEHGSDDSD 1173
Score = 40.0 bits (92), Expect = 0.004
Identities = 44/228 (19%), Positives = 74/228 (32%), Gaps = 28/228 (12%)
Query: 97 GDDTEDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTT 156
G D ++ + +PK+RR K KKK P + K ++++ D
Sbjct: 969 GSDDDETENGPKPKKRRPPK-AEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLK 1027
Query: 157 IS-----KNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGV 211
I+ +N + +RKK A + + N+ + EA
Sbjct: 1028 IADEGHPRNSNSNSDSDEDEQRKKCAS-----------SESDSDENQNKSGSEAGSPRRP 1076
Query: 212 DTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDARE 271
D ++ + R + E + R G SE D PA D
Sbjct: 1077 RRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSG--VSENDSRPASPSAESDHES 1134
Query: 272 EDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGE 319
E G D E G+ + E + S + + G E G+D +
Sbjct: 1135 ERGSD---------NEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
Score = 34.3 bits (77), Expect = 0.23
Identities = 47/241 (19%), Positives = 90/241 (37%), Gaps = 33/241 (13%)
Query: 103 QDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQR-QHTDGTTISKNK 161
Q+ + R+++ K + +K+ + E E+Q+ LL++++Q + T + +
Sbjct: 845 QEQEKELLRQKLLKEQEEKRLR----------EKEEQKKLLEQRAQYVEKTKNILMFTGE 894
Query: 162 KRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPED-------SSNEGEGVGEACEEDGVDTS 214
K+K KR G +K G + +D S + G E++G D
Sbjct: 895 TEATKEK---KRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
Query: 215 EEDPTLA-------GEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVK 267
+ GEE D E+G + +A +++ P+ G+ K
Sbjct: 952 GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSK 1011
Query: 268 DAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGAD-----SGEEDG 322
+ E+ L A E +++ +D E+ A E +D SG E G
Sbjct: 1012 AIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAG 1071
Query: 323 A 323
+
Sbjct: 1072 S 1072
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/255 (23%), Positives = 101/255 (39%), Gaps = 44/255 (17%)
Query: 85 PSSCGSPEN--------ASSGDDTEDQDPHDQPKRRRIRKHKSKKKFKNP---NNVLIEQ 133
P+ C PE + SG + D P + + S K +NP + + E
Sbjct: 83 PTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEES 142
Query: 134 AELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPE 193
++ E+Q+ L +QR K K K +KK +K K+A G KA+ + E
Sbjct: 143 SDEERQRDL---PAQRGEESSEEEEKGYKGKTRKKPVVK-KQAPG---KASVSRKQAREE 195
Query: 194 DSSNEGEGVGEACEE----DGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEE 249
+E E V ++ G + +E + EE + +E+ EE++ +EE
Sbjct: 196 SEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQ-----REEEVEEEEKEE 250
Query: 250 GADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWA 309
+ + P K AREE R+ ++ + R +D+ EE
Sbjct: 251 DEEKGDWKPRTRSNGRRKSAREE-----------RSCKQKSQAKRLLGDSDSEEE----- 294
Query: 310 GEEEGADSGEEDGAD 324
++E A SG++ G D
Sbjct: 295 -QKEAASSGDDSGRD 308
Score = 28.9 bits (63), Expect = 9.8
Identities = 41/225 (18%), Positives = 83/225 (36%), Gaps = 40/225 (17%)
Query: 101 EDQDPHDQPKRRRIRKHKSKKKFKNPNNVLIEQAELEKQQSLLQEKSQRQHTDGTTISKN 160
E ++ +P +R +K + K K+ ++++E E ++ +L +K +++ + + +
Sbjct: 195 ESEESEAEPVQRTAKKVEGNKGTKS-----LKESEQESEEEILAQKKEQREEE---VEEE 246
Query: 161 KKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGVDTSEEDPTL 220
+K + ++K K + + K+A EE + L
Sbjct: 247 EKEEDEEKGDWKPRTRSNGRRKSAR---------------------EERSCKQKSQAKRL 285
Query: 221 AGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPT--------PAGEEDVKDAREE 272
G+ D + EE AS D + +E ED T ED +D+ +
Sbjct: 286 LGDSD---SEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKG 342
Query: 273 DGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADS 317
+ + R G G+++ E SE GE + S
Sbjct: 343 EPTAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSS 387
>gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 1070
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/201 (23%), Positives = 77/201 (38%), Gaps = 18/201 (8%)
Query: 192 PEDSSNEGEGVGE--------ACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLT 243
PED+ G+ + + E GVD E+ P A + +EEDG + +
Sbjct: 344 PEDARPTEHGIDQEEDGPEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPT-- 401
Query: 244 RARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDG-KDTREEDGADAS 302
E G D E+ P A + +EEDG + +EDG +D R +
Sbjct: 402 ----EHGVDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHGVDQEDGPEDARPTEHGVDQ 457
Query: 303 EEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLKSTQE---MYFYDGVSRD 359
E+ P A E E+ DAS + + + + FL S ++ + F S
Sbjct: 458 EDGPEDARPTEHGVDQEDGPEDASRTEHGVGHRAGRACAAFLSSRRDNLYLSFKKANSAH 517
Query: 360 AASAALADAAEELLDRLASHS 380
+ + ELLD + H+
Sbjct: 518 VTGIISSRSDSELLDWNSKHT 538
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/145 (28%), Positives = 62/145 (42%), Gaps = 6/145 (4%)
Query: 194 DSSNEGEGVGEACE-EDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGAD 252
D E +G +A E GVD E+ P A + +E+ DAS + +QE+G +
Sbjct: 286 DVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQEDGPE 345
Query: 253 ASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG-E 311
+ PT G + +D E+ + D G ED T E G D E+ P A
Sbjct: 346 --DARPTEHGIDQEEDGPEDASLTEHGVDQQEDGPEDASPT--EHGIDQEEDGPEDASPT 401
Query: 312 EEGADSGEEDGADASEEDDTITNEK 336
E G D E+ DAS + + E+
Sbjct: 402 EHGVDQEEDGPEDASPTEHGVDQEE 426
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,884,714
Number of Sequences: 37866
Number of extensions: 1128168
Number of successful extensions: 15359
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 719
Number of HSP's that attempted gapping in prelim test: 5579
Number of HSP's gapped (non-prelim): 4275
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.