Search of human proteins with 46309463

Search of human proteins with 46309463

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46309463 vitamin K epoxide reductase complex, subunit 1-like
1 [Homo sapiens]
         (176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46309463 vitamin K epoxide reductase complex, subunit 1-like ...   352   7e-98
gi|13124770 vitamin K epoxide reductase complex, subunit 1 isofo...   162   1e-40
gi|45827739 vitamin K epoxide reductase complex, subunit 1 isofo...    54   5e-08
gi|16933561 sarcospan isoform 1 [Homo sapiens]                         30   1.1  
gi|23397518 hypothetical protein LOC169693 [Homo sapiens]              29   1.8  
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          29   2.4  
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          29   2.4  
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]         29   2.4  
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          29   2.4  
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]          29   2.4  
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]          29   2.4  
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          29   2.4  
gi|169171558 PREDICTED: hypothetical protein [Homo sapiens]            29   2.4  
gi|14210520 solute carrier family 30, member 2 isoform 2 [Homo s...    29   2.4  
gi|52352805 solute carrier family 30, member 2 isoform 1 [Homo s...    29   2.4  
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ...    28   3.1  
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ...    28   3.1  
gi|21389473 transmembrane protein 42 [Homo sapiens]                    27   7.0  
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    27   9.2  
gi|133778974 transketolase-like 2 [Homo sapiens]                       27   9.2  

>gi|46309463 vitamin K epoxide reductase complex, subunit 1-like 1
           [Homo sapiens]
          Length = 176

 Score =  352 bits (904), Expect = 7e-98
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSA 60
           MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSA
Sbjct: 1   MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSA 60

Query: 61  ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS 120
           ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS
Sbjct: 61  ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS 120

Query: 121 VVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD 176
           VVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD
Sbjct: 121 VVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD 176


>gi|13124770 vitamin K epoxide reductase complex, subunit 1 isoform
           1 [Homo sapiens]
          Length = 163

 Score =  162 bits (411), Expect = 1e-40
 Identities = 72/149 (48%), Positives = 111/149 (74%), Gaps = 3/149 (2%)

Query: 12  PRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFG 71
           P W R+A   +C  G++LS+YA HV+  + RD ++RALCD+G  + CS   +SRWGRGFG
Sbjct: 8   PGWVRLA---LCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFG 64

Query: 72  LLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYIL 131
           L+  + G+D +LNQ NS+FG IFY LQLLLG   +  A+++++ SS++S+ GS+YLA+IL
Sbjct: 65  LVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWIL 124

Query: 132 YFVLKEFCIICIVTYVLNFLLLIINYKRL 160
           +FVL +FCI+CI TY +N  L+ ++++++
Sbjct: 125 FFVLYDFCIVCITTYAINVSLMWLSFRKV 153


>gi|45827739 vitamin K epoxide reductase complex, subunit 1
          isoform 2 [Homo sapiens]
          Length = 92

 Score = 54.3 bits (129), Expect = 5e-08
 Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)

Query: 12 PRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASR 65
          P W R+A   +C  G++LS+YA HV+  + RD ++RALCD+G  + CS   +SR
Sbjct: 8  PGWVRLA---LCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSR 58


>gi|16933561 sarcospan isoform 1 [Homo sapiens]
          Length = 243

 Score = 30.0 bits (66), Expect = 1.1
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 10/69 (14%)

Query: 90  FGLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLN 149
           F L+  +LQL LG+  + V  L+   SS + V  + + A I         I+C+V Y L 
Sbjct: 52  FPLLLALLQLALGIAVTVVGFLMASISSSLLVRDTPFWAGI---------IVCLVAY-LG 101

Query: 150 FLLLIINYK 158
             +L ++Y+
Sbjct: 102 LFMLCVSYQ 110


>gi|23397518 hypothetical protein LOC169693 [Homo sapiens]
          Length = 170

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/41 (39%), Positives = 20/41 (48%)

Query: 91  GLIFYILQLLLGMTASAVAALILMTSSIMSVVGSLYLAYIL 131
           GLI   L LL+G     + A  +   SI    GSL  AY+L
Sbjct: 6   GLILCALALLMGFLMVCLGAFFISWGSIFDCQGSLIAAYLL 46


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 197 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 244


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 129 YILYFVLKEFCIIC-IVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQ 175
           Y ++ V K + I C +V + + FLL+++ Y R+    +    Q+Q  Q
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQ 230


>gi|169171558 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 303

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 9/75 (12%)

Query: 95  YILQLLLGMTASAVAALILMTSSIMSVVGSL-------YLAYILYFVLKEFCIICIVTYV 147
           Y+ ++  G    AVA  I++   I+ V+G         Y+A +L+ +   FCII + T V
Sbjct: 175 YLRRMTAGFMGMAVA--IILFGWIIGVLGCCWDRGLMQYVAGLLFLMGGTFCIISLCTCV 232

Query: 148 LNFLLLIINYKRLVY 162
                 +  Y R +Y
Sbjct: 233 AGINFELSRYPRYLY 247


>gi|14210520 solute carrier family 30, member 2 isoform 2 [Homo
           sapiens]
          Length = 323

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 18/48 (37%), Positives = 25/48 (52%)

Query: 106 SAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLL 153
           S  AA I +    M  +G L  AYILYF  +   +  I T+V + L+L
Sbjct: 167 SVRAAFIHVIGDFMQSMGVLVAAYILYFKPEYKYVDPICTFVFSILVL 214


>gi|52352805 solute carrier family 30, member 2 isoform 1 [Homo
           sapiens]
          Length = 372

 Score = 28.9 bits (63), Expect = 2.4
 Identities = 18/48 (37%), Positives = 25/48 (52%)

Query: 106 SAVAALILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLL 153
           S  AA I +    M  +G L  AYILYF  +   +  I T+V + L+L
Sbjct: 216 SVRAAFIHVIGDFMQSMGVLVAAYILYFKPEYKYVDPICTFVFSILVL 263


>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
            sapiens]
          Length = 1642

 Score = 28.5 bits (62), Expect = 3.1
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 111  LILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLI-INYKRLVYLNEAW 167
            LILM  S+++    LY  Y + F+   FC+I  V  V+ F  +    +K+++   E W
Sbjct: 1081 LILMLGSLLAFHYGLYF-YTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFW 1137


>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
            sapiens]
          Length = 1642

 Score = 28.5 bits (62), Expect = 3.1
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 111  LILMTSSIMSVVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLI-INYKRLVYLNEAW 167
            LILM  S+++    LY  Y + F+   FC+I  V  V+ F  +    +K+++   E W
Sbjct: 1081 LILMLGSLLAFHYGLYF-YTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFW 1137


>gi|21389473 transmembrane protein 42 [Homo sapiens]
          Length = 159

 Score = 27.3 bits (59), Expect = 7.0
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 17/94 (18%)

Query: 61  ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS 120
           A  S    G  +LG I     V+   NS+    F       G++ S  +A+  +T +  +
Sbjct: 60  AFGSEVSMGLCVLGII-----VMASTNSLMWTFFS-----RGLSFSMSSAIASVTVTFSN 109

Query: 121 VVGSLYLAYILYFVLKE-------FCIICIVTYV 147
           ++ S +L Y+LY   +E       F I+C +T +
Sbjct: 110 ILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLI 143


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 26.9 bits (58), Expect = 9.2
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 13/136 (9%)

Query: 17  VARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSI 76
           +A + V AA  L  +  Y++  EK   P        GP  K   A  S       LLGSI
Sbjct: 301 MAYFGVSAA--LTLMMPYYLLDEKSPLPVAFEYVGWGP-AKYVVAAGSLCALSTSLLGSI 357

Query: 77  FGKDGVLNQPNSVFGLIFYILQ---------LLLGMTASAVAALILMTSSIMSVVGSLYL 127
           F    V+    +  GL+F  L          ++  +++ AVAAL+     + ++V  + +
Sbjct: 358 FPMPRVI-YAMAEDGLLFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSI 416

Query: 128 AYILYFVLKEFCIICI 143
             ++ + L   C++ +
Sbjct: 417 GTLMAYSLVAACVLIL 432


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score = 26.9 bits (58), Expect = 9.2
 Identities = 9/24 (37%), Positives = 16/24 (66%)

Query: 23 CAAGILLSIYAYHVEREKERDPEH 46
          C+A  ++S+  +H  + K+ DPEH
Sbjct: 43 CSAAEVVSVLFFHTMKYKQTDPEH 66


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.143    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,099,868
Number of Sequences: 37866
Number of extensions: 233088
Number of successful extensions: 755
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 748
Number of HSP's gapped (non-prelim): 20
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.