Search of human proteins with 46255066

Search of human proteins with 46255066

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             760   0.0  
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            760   0.0  
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            760   0.0  
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             760   0.0  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]             760   0.0  
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]             760   0.0  
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             738   0.0  
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             667   0.0  
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            667   0.0  
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       328   4e-90
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      294   1e-79
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      294   1e-79
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            259   3e-69
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             259   3e-69
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            257   1e-68
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      195   6e-50
gi|238550198 synaptotagmin III [Homo sapiens]                         112   7e-25
gi|238550196 synaptotagmin III [Homo sapiens]                         112   7e-25
gi|14150054 synaptotagmin III [Homo sapiens]                          112   7e-25
gi|45504376 synaptotagmin VI [Homo sapiens]                           111   9e-25
gi|211059429 synaptotagmin II [Homo sapiens]                          110   2e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           110   2e-24
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            107   1e-23
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             107   1e-23
gi|39752671 synaptotagmin X [Homo sapiens]                            107   2e-23
gi|6005997 double C2-like domains, beta [Homo sapiens]                107   2e-23
gi|209447073 synaptotagmin I [Homo sapiens]                           102   7e-22
gi|5032139 synaptotagmin I [Homo sapiens]                             102   7e-22
gi|209447070 synaptotagmin I [Homo sapiens]                           102   7e-22
gi|28376627 synaptotagmin IX [Homo sapiens]                           101   1e-21

>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 361 EATLPLRMLLIAKISK 376
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 560 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 619

Query: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 620 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 679

Query: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 680 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 739

Query: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 740 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 799

Query: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 800 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 859

Query: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 860 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 919

Query: 361 EATLPLRMLLIAKISK 376
           EATLPLRMLLIAKISK
Sbjct: 920 EATLPLRMLLIAKISK 935


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 559 MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 618

Query: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 619 YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 678

Query: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 679 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 738

Query: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 739 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 798

Query: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 799 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 858

Query: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 859 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 918

Query: 361 EATLPLRMLLIAKISK 376
           EATLPLRMLLIAKISK
Sbjct: 919 EATLPLRMLLIAKISK 934


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 361 EATLPLRMLLIAKISK 376
           EATLPLRMLLIAKISK
Sbjct: 361 EATLPLRMLLIAKISK 376


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1    MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
            MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 881  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 940

Query: 61   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 941  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1000

Query: 121  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 1001 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1060

Query: 181  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 1061 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1120

Query: 241  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 1121 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1180

Query: 301  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 1181 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1240

Query: 361  EATLPLRMLLIAKISK 376
            EATLPLRMLLIAKISK
Sbjct: 1241 EATLPLRMLLIAKISK 1256


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1    MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
            MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 897  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 956

Query: 61   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 957  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1016

Query: 121  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 1017 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1076

Query: 181  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 1077 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1136

Query: 241  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 1137 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1196

Query: 301  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 1197 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1256

Query: 361  EATLPLRMLLIAKISK 376
            EATLPLRMLLIAKISK
Sbjct: 1257 EATLPLRMLLIAKISK 1272


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 13  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 72
           SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 2   SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61

Query: 73  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 132
           NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 62  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121

Query: 133 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 192
           TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181

Query: 193 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 252
           RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241

Query: 253 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 312
           HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 242 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301

Query: 313 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 372
           KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 302 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361

Query: 373 KISK 376
           KISK
Sbjct: 362 KISK 365


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  667 bits (1721), Expect = 0.0
 Identities = 328/342 (95%), Positives = 329/342 (96%)

Query: 35  PSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC 94
           P  L  +S S        VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC
Sbjct: 569 PDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQC 628

Query: 95  KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ 154
           KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ
Sbjct: 629 KDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQ 688

Query: 155 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM 214
           KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM
Sbjct: 689 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEM 748

Query: 215 KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT 274
           KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT
Sbjct: 749 KLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKT 808

Query: 275 RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT 334
           RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT
Sbjct: 809 RAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGT 868

Query: 335 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 376
           EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Sbjct: 869 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK 910


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 1   MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 1   MSKSVPAFLQDE----------------------------------------VSGSVMSV 20

Query: 61  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120
           YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 21  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80

Query: 121 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180
           KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 81  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140

Query: 181 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240
           TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 141 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200

Query: 241 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300
           KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 201 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260

Query: 301 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360
           EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 261 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320

Query: 361 EATLPLRMLLIAKISK 376
           EATLPLRMLLIAKISK
Sbjct: 321 EATLPLRMLLIAKISK 336


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  328 bits (842), Expect = 4e-90
 Identities = 167/335 (49%), Positives = 229/335 (68%), Gaps = 11/335 (3%)

Query: 35  PSSLTNLSSSSGMTSLSS--VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVA 92
           PS    LSSSS ++SL+S  +SGS MS+ SGD   ++V+G++ FA+ Y     EL V V 
Sbjct: 218 PSLDRMLSSSSSVSSLNSSTLSGSQMSL-SGDAEAVQVRGSVHFALHYEPGAAELRVHVI 276

Query: 93  QCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILK 152
           QC+ LAAA  +++RSDPYVK+YLLPDK    K+KT V K+ LNPV+NE LRY + +  L+
Sbjct: 277 QCQGLAAA--RRRRSDPYVKSYLLPDK--QSKRKTAVKKRNLNPVFNETLRYSVPQAELQ 332

Query: 153 TQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRG 212
            + L+LS+WHR++  RN FLGEVE+ L+TWDW ++      W PL+ +  P   +  +RG
Sbjct: 333 GRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPT----WLPLQPRVPPSPDDLPSRG 388

Query: 213 EMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQ 272
            + L+L+YVP    G  LP +GE+H WVKE  DL  LR   L+++V+C +LPD S+ SRQ
Sbjct: 389 LLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPLRAGSLDTYVQCFVLPDDSQASRQ 448

Query: 273 KTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSY 332
           +TR V ++ +P+FNHTMVYDGF P DL +AC EL++WDH  L N+ LGG R+  GTG SY
Sbjct: 449 RTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALANRQLGGTRLSLGTGSSY 508

Query: 333 GTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367
           G +V WMDST EE  LW+ ++  P  W++  LPLR
Sbjct: 509 GLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLR 543


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  294 bits (752), Expect = 1e-79
 Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%)

Query: 2   SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61
           SKSVP    D  ++ E +   +   +L R K + SS+ + SS S +       GS+MS+Y
Sbjct: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345

Query: 62  S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119
           S  GDFGN+ V G I F+++Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK
Sbjct: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405

Query: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179
            + GK+KT + + T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +
Sbjct: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465

Query: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233
           ++W  D K +  L  +      +P  L + ++GE+ ++L+Y+P    PV G +  +    
Sbjct: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524

Query: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
            GE+ +W+KE  +L   + G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY
Sbjct: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584

Query: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350
           +G R EDL   C+ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+
Sbjct: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644

Query: 351 KMVNSPNTWIEATLPLR 367
           KM   P +W E TL LR
Sbjct: 645 KMRQYPGSWAEGTLQLR 661


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  294 bits (752), Expect = 1e-79
 Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%)

Query: 2   SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61
           SKSVP    D  ++ E +   +   +L R K + SS+ + SS S +       GS+MS+Y
Sbjct: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345

Query: 62  S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119
           S  GDFGN+ V G I F+++Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK
Sbjct: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405

Query: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179
            + GK+KT + + T+NP+Y+E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +
Sbjct: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465

Query: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233
           ++W  D K +  L  +      +P  L + ++GE+ ++L+Y+P    PV G +  +    
Sbjct: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524

Query: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
            GE+ +W+KE  +L   + G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY
Sbjct: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584

Query: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350
           +G R EDL   C+ELTVWD   L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+
Sbjct: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644

Query: 351 KMVNSPNTWIEATLPLR 367
           KM   P +W E TL LR
Sbjct: 645 KMRQYPGSWAEGTLQLR 661


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  259 bits (662), Expect = 3e-69
 Identities = 156/393 (39%), Positives = 230/393 (58%), Gaps = 42/393 (10%)

Query: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+    MSV
Sbjct: 345 SKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSV 394

Query: 61  YS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPD 118
           YS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPD
Sbjct: 395 YSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPD 454

Query: 119 KGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD 178
           K +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+ 
Sbjct: 455 KSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIP 513

Query: 179 LETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPG 227
            ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G
Sbjct: 514 FDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQG 569

Query: 228 KK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTR 275
            K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT 
Sbjct: 570 NKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTL 629

Query: 276 AVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGT 334
            + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G 
Sbjct: 630 VIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGK 689

Query: 335 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367
            VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 690 NVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  259 bits (662), Expect = 3e-69
 Identities = 156/393 (39%), Positives = 230/393 (58%), Gaps = 42/393 (10%)

Query: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60
           SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+    MSV
Sbjct: 345 SKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM----MSV 394

Query: 61  YS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPD 118
           YS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK+YLLPD
Sbjct: 395 YSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPD 454

Query: 119 KGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD 178
           K +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFLGEVE+ 
Sbjct: 455 KSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIP 513

Query: 179 LETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV---------PEPVPG 227
            ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         PE + G
Sbjct: 514 FDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLPPEQLQG 569

Query: 228 KK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTR 275
            K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ ++ KT 
Sbjct: 570 NKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTL 629

Query: 276 AVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGT 334
            + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+G S+G 
Sbjct: 630 VIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGK 689

Query: 335 EVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367
            VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 690 NVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  257 bits (657), Expect = 1e-68
 Identities = 156/405 (38%), Positives = 232/405 (57%), Gaps = 44/405 (10%)

Query: 2   SKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------------ 48
           SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G              
Sbjct: 345 SKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDAD 404

Query: 49  SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQR 106
           S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR
Sbjct: 405 SDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQR 464

Query: 107 SDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTF 166
           +D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F
Sbjct: 465 TDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRF 523

Query: 167 KRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--- 221
            RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+   
Sbjct: 524 GRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPE 579

Query: 222 ------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 263
                 PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +L
Sbjct: 580 ENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLL 639

Query: 264 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 322
           PD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+
Sbjct: 640 PDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGV 699

Query: 323 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 367
           R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 700 RLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  195 bits (495), Expect = 6e-50
 Identities = 124/348 (35%), Positives = 188/348 (54%), Gaps = 27/348 (7%)

Query: 40  NLSSSSGMTSLSSVS---GSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFV 91
           NL SS   +++ S     GS++S+ S     G+F N  V G I+FAI Y      L + +
Sbjct: 200 NLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICI 259

Query: 92  AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 151
             CK+LA  + KK++ +PYVK YLLPD+   GK+KT V + T++P + E L+Y++    L
Sbjct: 260 KACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQL 319

Query: 152 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-EN 210
            T++L +S+WH  T  R  FLGEV + L TWD+++   +  RW+PL+ K         ++
Sbjct: 320 VTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQS 379

Query: 211 RGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-C 260
            GE+    KL L   P    E   G   P+  G++ + V    +LP+     LNSFVK C
Sbjct: 380 NGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGC 439

Query: 261 TILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQF 318
             LPD  +K R K+  + K   P + H+ V+ G  P  L ++ +ELTVWD   + + ++ 
Sbjct: 440 LTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRL 498

Query: 319 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 366
           LGG R+G     S G      D+ S     W+K+++SPN W + TL L
Sbjct: 499 LGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 62  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 121
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 122 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 179
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 239
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 240 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 298
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 299 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 353
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 62  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 121
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 122 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 179
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 239
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 240 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 298
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 299 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 353
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 7e-25
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 62  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 121
           SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 122 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 179
             K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 239
           E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408 ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 240 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 298
           + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452 IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 299 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 353
           +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511 VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  111 bits (278), Expect = 9e-25
 Identities = 84/295 (28%), Positives = 152/295 (51%), Gaps = 25/295 (8%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G I F++ Y    + L V + +  DL A D     SDPYVK YLLPD+    K +T V +
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHR 202

Query: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 191
           KTLNP ++E   + +  + L  +KL+LS++  D F R+  +GEV LD   ++  +   + 
Sbjct: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRET 261

Query: 192 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 250
             W  ++  T+    E+ + GE+  +L Y         LPT G + + V +C +L  +  
Sbjct: 262 SIWKDIQYATS----ESVDLGEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDI 308

Query: 251 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 310
             + + +VK ++L D  R  ++KT     T NP++N  +++D   PE++ +  + ++V D
Sbjct: 309 TGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMD 367

Query: 311 HYKL-TNQFLGGLRIGF---GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 361
           + ++  N+ +G  R+G    G G+ +  E+  +    + +A W  +V    ++ E
Sbjct: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 6/189 (3%)

Query: 11  DESDDRETDTASESSYQLSRHKK-SPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLE 69
           +E  DR+   +     + SRH       L NL  +S ++  +S+   +    S       
Sbjct: 220 EELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVD--- 276

Query: 70  VKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLV 129
             G I F++ Y+ +   L + V +C++L A D+    SDPYVK  LL D  ++ KKKT +
Sbjct: 277 -LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY-SDPYVKVSLLCDGRRLKKKKTTI 334

Query: 130 VKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQN 189
            K TLNPVYNE + + I  + +    L +S+   D    N  +G   + +          
Sbjct: 335 KKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHW 394

Query: 190 KQLRWYPLK 198
            ++  YP K
Sbjct: 395 NEMLAYPRK 403


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 191
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 192 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 250
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 251 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 310
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 311 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 364
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 69  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 128
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 129 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 181
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 182 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 211
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 2e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 191
           KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 192 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 250
             W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257 --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 251 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 310
           G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303 GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 311 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 364
           + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362 YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 69  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 128
           E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 129 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 181
           V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 182 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 211
           W     N +    +W+ LK +    AL  +N+
Sbjct: 388 WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 394 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 452

Query: 132 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 190
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 453 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512

Query: 191 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 232
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 513 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 563

Query: 233 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 564 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 623

Query: 292 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 349
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 624 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 682

Query: 350 EKMVN 354
            ++ N
Sbjct: 683 HQLQN 687



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 66  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 125
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 546 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 604

Query: 126 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 178
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 605 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 179 LETW--DWDNKQNKQLRWYPLKRK 200
           L+ W     NK  K  RW+ L+ +
Sbjct: 665 LKHWYECLKNKDKKIERWHQLQNE 688


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  107 bits (268), Expect = 1e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 390 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448

Query: 132 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 190
            T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508

Query: 191 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 232
            +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559

Query: 233 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
            G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 560 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619

Query: 292 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 349
           D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 620 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678

Query: 350 EKMVN 354
            ++ N
Sbjct: 679 HQLQN 683



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 66  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 125
           G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600

Query: 126 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 178
           KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 179 LETW--DWDNKQNKQLRWYPLKRK 200
           L+ W     NK  K  RW+ L+ +
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQNE 684


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/276 (28%), Positives = 144/276 (52%), Gaps = 25/276 (9%)

Query: 67  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 126
           ++++ G + F ++Y    + L V + +  DL A D     SDPYVK YLLPD+ K  K +
Sbjct: 228 DVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGT-SDPYVKMYLLPDRKK--KFQ 284

Query: 127 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDN 186
           T V +KTLNP+++E  ++ +    L  +KL+ S++  D F R+  +GEV LD   ++  +
Sbjct: 285 TRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD-NLFEVSD 343

Query: 187 KQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 246
              +   W  +   T     E+ + GE+  +L Y         LPT G + + V +C +L
Sbjct: 344 LSREATVWKDIHCATT----ESIDLGEIMFSLCY---------LPTAGRMTLTVIKCRNL 390

Query: 247 PL--LRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 304
               + GS  + +VK +++ +  R  ++KT     T NP++N  +++D   PE++ +  +
Sbjct: 391 KAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSL 448

Query: 305 ELTVWDHYKL-TNQFLGGLRIGF---GTGKSYGTEV 336
            + V D+ ++  N+ +G  R G    G G+ +  E+
Sbjct: 449 SIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEM 484


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  107 bits (266), Expect = 2e-23
 Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 23/291 (7%)

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G + F++ Y +    LH  + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMD-HNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 132 KTLNPVYNEILR-YKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 190
            TLNP +NE L  Y I  + +  + L +S+   D F+ N F+GE  + L+      K N 
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL----KPNH 242

Query: 191 QLRWYPLKRKTAPV----ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 246
              +     K  PV        E RG + ++L+Y  +            + + +  C  L
Sbjct: 243 TKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQ---------KQGLLVGIVRCAHL 293

Query: 247 PLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE 305
             +    + + +VK  + PD  +KS+ KT    KT NP FN    Y+  +  DL +  +E
Sbjct: 294 AAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLE 352

Query: 306 LTVWDH-YKLTNQFLGGLRIGF-GTGKSYGTEVDWMDSTSEEVALWEKMVN 354
           +TVWD+    +N F+GG+ +G    G+      D + +  + +  W  + +
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTS 403



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 67  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 126
           +LE +G I  +++Y    + L V + +C  LAA D     SDPYVK YL PD  K  K K
Sbjct: 263 SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHK 321

Query: 127 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD-------L 179
           T V KKTLNP +NE   Y+I+   L  + L +++W  D  K N F+G V L        L
Sbjct: 322 TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERL 381

Query: 180 ETW--DWDNKQNKQLRWYPL 197
           + W     NK  +  RW+ L
Sbjct: 382 KHWFDCLKNKDKRIERWHTL 401


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 69  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 128
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 129 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 188
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 189 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 248
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 249 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 307
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 308 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 356
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 69  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 128
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 129 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 188
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 189 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 248
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 249 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 307
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 308 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 356
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 69  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 128
           E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 129 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 188
           V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198 VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 189 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 248
            +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258 EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 249 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 307
           +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303 MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 308 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 356
           V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362 VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  101 bits (252), Expect = 1e-21
 Identities = 86/347 (24%), Positives = 169/347 (48%), Gaps = 31/347 (8%)

Query: 18  TDTASESSYQLSRHKKSPS-SLTNLSSSSGMTSLSSVSGSVMSVYS-----GDFGNLEVK 71
           T +A  +S +   +  +P  ++  L     +T +  +   +    S     G   N +  
Sbjct: 162 TSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKAC 221

Query: 72  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
           G + F ++Y   L++L V + +  +L A D     SDPYVK YLLPD+    K +T V +
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKT--KHQTKVHR 278

Query: 132 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 191
           KTLNPV++E+  + +    L+ +KL+ S++  D F R+  +G+V +D    D  +   + 
Sbjct: 279 KTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD-HFLDLADFPREC 337

Query: 192 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 251
           + W  ++     V  +  + GE+  +L Y         LPT G + I + +  +L  +  
Sbjct: 338 ILWKDIEY----VTNDNVDLGELMFSLCY---------LPTAGRLTITIIKARNLKAMDI 384

Query: 252 SHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 310
           +  +  +VK +++ D  R  ++KT     T NP++N  +V+D   PE++ +  + + V D
Sbjct: 385 TGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFD-VPPENIDQIHLSIAVMD 443

Query: 311 HYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDSTSEEVALWEKMV 353
           + ++  N+ +G  ++G      G+ + +E+  +    + +A W  +V
Sbjct: 444 YDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSYPRKPIAHWHSLV 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,956,755
Number of Sequences: 37866
Number of extensions: 622894
Number of successful extensions: 2486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 2048
Number of HSP's gapped (non-prelim): 320
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.