Search of human proteins with 46255062

Search of human proteins with 46255062

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
         (1272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]            2538   0.0  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]            2492   0.0  
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]            889   0.0  
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]            889   0.0  
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]             842   0.0  
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]             760   0.0  
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]             760   0.0  
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]             738   0.0  
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]            667   0.0  
gi|14249614 synaptotagmin-like 1 [Homo sapiens]                       332   1e-90
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      298   2e-80
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      298   2e-80
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            260   7e-69
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]             260   7e-69
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            258   3e-68
gi|110227631 synaptotagmin-like 3 [Homo sapiens]                      195   3e-49
gi|39752671 synaptotagmin X [Homo sapiens]                            115   2e-25
gi|45504376 synaptotagmin VI [Homo sapiens]                           115   3e-25
gi|238550198 synaptotagmin III [Homo sapiens]                         112   3e-24
gi|238550196 synaptotagmin III [Homo sapiens]                         112   3e-24
gi|14150054 synaptotagmin III [Homo sapiens]                          112   3e-24
gi|211059429 synaptotagmin II [Homo sapiens]                          110   9e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           110   9e-24
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            107   6e-23
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             107   6e-23
gi|6005997 double C2-like domains, beta [Homo sapiens]                107   9e-23
gi|209447073 synaptotagmin I [Homo sapiens]                           102   3e-21
gi|5032139 synaptotagmin I [Homo sapiens]                             102   3e-21
gi|209447070 synaptotagmin I [Homo sapiens]                           102   3e-21
gi|28376627 synaptotagmin IX [Homo sapiens]                           101   4e-21

>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score = 2538 bits (6578), Expect = 0.0
 Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)

Query: 1    MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK 60
            MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK
Sbjct: 1    MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK 60

Query: 61   LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS 120
            LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS
Sbjct: 61   LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS 120

Query: 121  KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA 180
            KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA
Sbjct: 121  KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA 180

Query: 181  IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN 240
            IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN
Sbjct: 181  IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN 240

Query: 241  SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL 300
            SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL
Sbjct: 241  SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL 300

Query: 301  APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP 360
            APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP
Sbjct: 301  APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP 360

Query: 361  PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA 420
            PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA
Sbjct: 361  PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA 420

Query: 421  GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG 480
            GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG
Sbjct: 421  GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG 480

Query: 481  SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE 540
            SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE
Sbjct: 481  SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE 540

Query: 541  ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG 600
            ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG
Sbjct: 541  ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG 600

Query: 601  FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG 660
            FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG
Sbjct: 601  FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG 660

Query: 661  LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS 720
            LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS
Sbjct: 661  LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS 720

Query: 721  ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK 780
            ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK
Sbjct: 721  ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK 780

Query: 781  EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD 840
            EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD
Sbjct: 781  EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD 840

Query: 841  SSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKS 900
            SSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKS
Sbjct: 841  SSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKS 900

Query: 901  VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD 960
            VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD
Sbjct: 901  VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD 960

Query: 961  FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK 1020
            FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK
Sbjct: 961  FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK 1020

Query: 1021 KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW 1080
            KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW
Sbjct: 1021 KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW 1080

Query: 1081 DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL 1140
            DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL
Sbjct: 1081 DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL 1140

Query: 1141 DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 1200
            DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV
Sbjct: 1141 DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 1200

Query: 1201 ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL 1260
            ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL
Sbjct: 1201 ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL 1260

Query: 1261 PLRMLLIAKISK 1272
            PLRMLLIAKISK
Sbjct: 1261 PLRMLLIAKISK 1272


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score = 2492 bits (6459), Expect = 0.0
 Identities = 1255/1272 (98%), Positives = 1256/1272 (98%), Gaps = 16/1272 (1%)

Query: 1    MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK 60
            MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK
Sbjct: 1    MDEPNAEQVYNPSQFENLRKFWDLEANSNSKDNDKNITTTSQKNSAPFNRQKHKEFSDIK 60

Query: 61   LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS 120
            LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS
Sbjct: 61   LSGKNTHEAEVLLSPKKVMAREEMEKLNSKGILQVLPDEITFPLSPLRKYTYQLPGNESS 120

Query: 121  KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA 180
            KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA
Sbjct: 121  KENVEKNTEGIVTPVFKEEKDYSEQEIQESIIKTNVLSKDCKDTFNDSLQKLLSETSTPA 180

Query: 181  IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN 240
            IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN
Sbjct: 181  IQPSGGKVHGKQVLEPSVSENRTWPQKTDFADTEEEVKGPEKIINEHVDKTVVHPKVKRN 240

Query: 241  SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL 300
            SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL
Sbjct: 241  SLTASLDKLLKEATGTSPSPLQAKLAPVITGTNSKLEEGRFFGKGIEQSHNTSADKREIL 300

Query: 301  APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP 360
            APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP
Sbjct: 301  APFPVRDETFGNTALLKKAESGECQLSTQNLIQMAAEDSHPLDPTSQLSRKGSFGDVASP 360

Query: 361  PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA 420
            PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA
Sbjct: 361  PQDMLFPQDAHLVPQARVHPSQTEISETVEKVILPPRPVLNDVSAALQKLCGEVWLSYPA 420

Query: 421  GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG 480
            GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG
Sbjct: 421  GREVGPGEVNPEFPEAVQPVCSPLNPPGVISPWATMDTIVPDRKDFYSSNVVPDKTHEVG 480

Query: 481  SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE 540
            SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE
Sbjct: 481  SYLAAQMSPSDQTLSSFASIVAQYGKGLPQEVEEIVRETIVQPKSEFLEFSAGLEKLLKE 540

Query: 541  ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG 600
            ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG
Sbjct: 541  ETETFPSKYESDTGNLSPSKLIGSTEEPRRATSECHPEELKETVEKAEAPLITESAFDAG 600

Query: 601  FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG 660
            FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG
Sbjct: 601  FEKLLKEITEAPPYQPQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNG 660

Query: 661  LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS 720
            LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS
Sbjct: 661  LESQVNQCDKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDS 720

Query: 721  ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK 780
            ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK
Sbjct: 721  ESGVAGGQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEK 780

Query: 781  EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD 840
            EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD
Sbjct: 781  EEEKEGFSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSD 840

Query: 841  SSNQAKVDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKS 900
            SSNQAKVDNQPEELVRSAED                +STVPTQPDNPFSHPDKLKRMSKS
Sbjct: 841  SSNQAKVDNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKS 884

Query: 901  VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD 960
            VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD
Sbjct: 885  VPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGD 944

Query: 961  FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK 1020
            FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK
Sbjct: 945  FGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGK 1004

Query: 1021 KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW 1080
            KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW
Sbjct: 1005 KKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDW 1064

Query: 1081 DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL 1140
            DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL
Sbjct: 1065 DNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECL 1124

Query: 1141 DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 1200
            DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV
Sbjct: 1125 DLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 1184

Query: 1201 ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL 1260
            ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL
Sbjct: 1185 ELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATL 1244

Query: 1261 PLRMLLIAKISK 1272
            PLRMLLIAKISK
Sbjct: 1245 PLRMLLIAKISK 1256


>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
          Length = 935

 Score =  889 bits (2298), Expect = 0.0
 Identities = 482/665 (72%), Positives = 514/665 (77%), Gaps = 40/665 (6%)

Query: 616  PQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQC 668
            P +++ E   EKE S  + +      P  +   S   +   +S GL       E  V + 
Sbjct: 303  PGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES 362

Query: 669  DKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQ 728
            D++  G        ++  G     +    P  Y    +    T +P   + SE+      
Sbjct: 363  DRLKNG--------MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSK-SETHQPMTS 413

Query: 729  GTLQEPGFGEASEAISVS-RNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEGF 787
            G+    G    SE ++   ++ +  P +    N  K    ELT     + +   +E    
Sbjct: 414  GSFPINGLHSHSEVLTARPQSMENSPTI----NEPKDKSSELTRLESVLPRSPADELSHC 469

Query: 788  SESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 847
             E + S     S+ +       SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV
Sbjct: 470  VEPEPSQVPGGSSRD---RQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 526

Query: 848  DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 907
            DNQPEELVRSAED                +STVPTQPDNPFSHPDKLKRMSKSVPAFLQD
Sbjct: 527  DNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 570

Query: 908  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 967
            ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK
Sbjct: 571  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 630

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK
Sbjct: 631  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 690

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ
Sbjct: 691  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 750

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 1147
            LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG
Sbjct: 751  LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 810

Query: 1148 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 1207
            SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH
Sbjct: 811  SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 870

Query: 1208 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 1267
            YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI
Sbjct: 871  YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 930

Query: 1268 AKISK 1272
            AKISK
Sbjct: 931  AKISK 935


>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
          Length = 934

 Score =  889 bits (2298), Expect = 0.0
 Identities = 482/665 (72%), Positives = 514/665 (77%), Gaps = 40/665 (6%)

Query: 616  PQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQC 668
            P +++ E   EKE S  + +      P  +   S   +   +S GL       E  V + 
Sbjct: 302  PGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES 361

Query: 669  DKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQ 728
            D++  G        ++  G     +    P  Y    +    T +P   + SE+      
Sbjct: 362  DRLKNG--------MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSK-SETHQPMTS 412

Query: 729  GTLQEPGFGEASEAISVS-RNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEGF 787
            G+    G    SE ++   ++ +  P +    N  K    ELT     + +   +E    
Sbjct: 413  GSFPINGLHSHSEVLTARPQSMENSPTI----NEPKDKSSELTRLESVLPRSPADELSHC 468

Query: 788  SESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 847
             E + S     S+ +       SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV
Sbjct: 469  VEPEPSQVPGGSSRD---RQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 525

Query: 848  DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 907
            DNQPEELVRSAED                +STVPTQPDNPFSHPDKLKRMSKSVPAFLQD
Sbjct: 526  DNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 569

Query: 908  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 967
            ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK
Sbjct: 570  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 629

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK
Sbjct: 630  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 689

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ
Sbjct: 690  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 749

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 1147
            LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG
Sbjct: 750  LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 809

Query: 1148 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 1207
            SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH
Sbjct: 810  SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 869

Query: 1208 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 1267
            YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI
Sbjct: 870  YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 929

Query: 1268 AKISK 1272
            AKISK
Sbjct: 930  AKISK 934


>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
          Length = 910

 Score =  842 bits (2174), Expect = 0.0
 Identities = 459/665 (69%), Positives = 490/665 (73%), Gaps = 64/665 (9%)

Query: 616  PQVSVREETHEKESSQSEQTRFLGTVPHFYRAASQTSEMKDKSNGL-------ESQVNQC 668
            P +++ E   EKE S  + +      P  +   S   +   +S GL       E  V + 
Sbjct: 302  PGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES 361

Query: 669  DKMLGGDALVTDLLVDFCGSRSGVEIPRTPQLYVAHEIGTIKTVTPPEDRDSESGVAGGQ 728
            D++  G        ++  G     +    P  Y    +    T +P   + SE+      
Sbjct: 362  DRLKNG--------MEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSK-SETHQPMTS 412

Query: 729  GTLQEPGFGEASEAISVS-RNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEGF 787
            G+    G    SE ++   ++ +  P +    N  K    ELT     + +   +E    
Sbjct: 413  GSFPINGLHSHSEVLTARPQSMENSPTI----NEPKDKSSELTRLESVLPRSPADELSHC 468

Query: 788  SESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 847
             E + S     S+ +       SEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV
Sbjct: 469  VEPEPSQVPGGSSRD---RQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKV 525

Query: 848  DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 907
            DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD
Sbjct: 526  DNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQD 585

Query: 908  ESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVK 967
            E                                        VSGSVMSVYSGDFGNLEVK
Sbjct: 586  E----------------------------------------VSGSVMSVYSGDFGNLEVK 605

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK
Sbjct: 606  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 665

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ
Sbjct: 666  KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 725

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 1147
            LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG
Sbjct: 726  LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 785

Query: 1148 SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 1207
            SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH
Sbjct: 786  SHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH 845

Query: 1208 YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 1267
            YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI
Sbjct: 846  YKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLI 905

Query: 1268 AKISK 1272
            AKISK
Sbjct: 906  AKISK 910


>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 897  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 956
            MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1    MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 957  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1016
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 1017 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1076
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 1077 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1136
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 1137 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1196
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 1197 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1256
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 1257 EATLPLRMLLIAKISK 1272
            EATLPLRMLLIAKISK
Sbjct: 361  EATLPLRMLLIAKISK 376


>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
          Length = 376

 Score =  760 bits (1963), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 897  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 956
            MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV
Sbjct: 1    MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 60

Query: 957  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1016
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 61   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 120

Query: 1017 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1076
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 121  KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 180

Query: 1077 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1136
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 181  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 240

Query: 1137 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1196
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 241  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 300

Query: 1197 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1256
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 301  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 360

Query: 1257 EATLPLRMLLIAKISK 1272
            EATLPLRMLLIAKISK
Sbjct: 361  EATLPLRMLLIAKISK 376


>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
          Length = 365

 Score =  738 bits (1904), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 909  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 968
            SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG
Sbjct: 2    SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 61

Query: 969  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 1028
            NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK
Sbjct: 62   NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121

Query: 1029 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 1088
            TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL
Sbjct: 122  TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181

Query: 1089 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 1148
            RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS
Sbjct: 182  RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 241

Query: 1149 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 1208
            HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY
Sbjct: 242  HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 301

Query: 1209 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 1268
            KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA
Sbjct: 302  KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIA 361

Query: 1269 KISK 1272
            KISK
Sbjct: 362  KISK 365


>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
          Length = 336

 Score =  667 bits (1720), Expect = 0.0
 Identities = 336/376 (89%), Positives = 336/376 (89%), Gaps = 40/376 (10%)

Query: 897  MSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSV 956
            MSKSVPAFLQDE                                        VSGSVMSV
Sbjct: 1    MSKSVPAFLQDE----------------------------------------VSGSVMSV 20

Query: 957  YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 1016
            YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG
Sbjct: 21   YSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKG 80

Query: 1017 KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 1076
            KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE
Sbjct: 81   KMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLE 140

Query: 1077 TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 1136
            TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV
Sbjct: 141  TWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWV 200

Query: 1137 KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 1196
            KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM
Sbjct: 201  KECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLM 260

Query: 1197 EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 1256
            EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI
Sbjct: 261  EACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWI 320

Query: 1257 EATLPLRMLLIAKISK 1272
            EATLPLRMLLIAKISK
Sbjct: 321  EATLPLRMLLIAKISK 336


>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
          Length = 550

 Score =  332 bits (852), Expect = 1e-90
 Identities = 179/415 (43%), Positives = 257/415 (61%), Gaps = 26/415 (6%)

Query: 849  NQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDE 908
            + PEE  ++ ED  + DQ+    E  P +         P   P + +  +K+    L++ 
Sbjct: 155  SDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEP--RPQQAQ--TKAASQILENG 210

Query: 909  SDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKG 968
             +    D +      L R   S SS+++L+SS+       +SGS MS+ SGD   ++V+G
Sbjct: 211  EEAPGPDPS------LDRMLSSSSSVSSLNSST-------LSGSQMSL-SGDAEAVQVRG 256

Query: 969  NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 1028
            ++ FA+ Y     EL V V QC+ LAAA  +++RSDPYVK+YLLPDK    K+KT V K+
Sbjct: 257  SVHFALHYEPGAAELRVHVIQCQGLAAA--RRRRSDPYVKSYLLPDK--QSKRKTAVKKR 312

Query: 1029 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 1088
             LNPV+NE LRY + +  L+ + L+LS+WHR++  RN FLGEVE+ L+TWDW ++     
Sbjct: 313  NLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDTWDWGSEPT--- 369

Query: 1089 RWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGS 1148
             W PL+ +  P   +  +RG + L+L+YVP    G  LP +GE+H WVKE  DL  LR  
Sbjct: 370  -WLPLQPRVPPSPDDLPSRGLLALSLKYVPAGSEGAGLPPSGELHFWVKEARDLLPLRAG 428

Query: 1149 HLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHY 1208
             L+++V+C +LPD S+ SRQ+TR V ++ +P+FNHTMVYDGF P DL +AC EL++WDH 
Sbjct: 429  SLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHG 488

Query: 1209 KLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
             L N+ LGG R+  GTG SYG +V WMDST EE  LW+ ++  P  W++  LPLR
Sbjct: 489  ALANRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALLEQPCEWVDGLLPLR 543


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  298 bits (764), Expect = 2e-80
 Identities = 189/538 (35%), Positives = 284/538 (52%), Gaps = 23/538 (4%)

Query: 740  SEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG---FSESDFSDGN 796
            SE I +S   +P          +   + ++    P  K  +E +KE    F       G 
Sbjct: 133  SEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGK 192

Query: 797  TSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVR 856
            ++  AES    S + +  S   +     +      K +    S    + +   Q    V 
Sbjct: 193  SALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVD 252

Query: 857  SAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDT 916
              E   K + + +        S +  +P++       L   SKSVP    D  ++ E + 
Sbjct: 253  EGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEED 312

Query: 917  ASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAI 974
              +   +L R K + SS+ + SS S +       GS+MS+YS  GDFGN+ V G I F++
Sbjct: 313  I-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSL 364

Query: 975  EYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVY 1034
            +Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y
Sbjct: 365  KYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLY 424

Query: 1035 NEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLK 1094
            +E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L  +   
Sbjct: 425  DETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKI 484

Query: 1095 RKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR- 1146
               +P  L + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +L   + 
Sbjct: 485  SAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKA 543

Query: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
            G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+ELTVWD
Sbjct: 544  GGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWD 603

Query: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
               L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E TL LR
Sbjct: 604  REPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  298 bits (764), Expect = 2e-80
 Identities = 189/538 (35%), Positives = 284/538 (52%), Gaps = 23/538 (4%)

Query: 740  SEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG---FSESDFSDGN 796
            SE I +S   +P          +   + ++    P  K  +E +KE    F       G 
Sbjct: 133  SEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGK 192

Query: 797  TSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVR 856
            ++  AES    S + +  S   +     +      K +    S    + +   Q    V 
Sbjct: 193  SALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVD 252

Query: 857  SAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDT 916
              E   K + + +        S +  +P++       L   SKSVP    D  ++ E + 
Sbjct: 253  EGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEED 312

Query: 917  ASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAI 974
              +   +L R K + SS+ + SS S +       GS+MS+YS  GDFGN+ V G I F++
Sbjct: 313  I-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSL 364

Query: 975  EYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVY 1034
            +Y +  + L V V +C  LA AD  K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y
Sbjct: 365  KYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLY 424

Query: 1035 NEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLK 1094
            +E LRY+I + +L  + L  S+WH   F RN+FLGE E+ +++W  D K +  L  +   
Sbjct: 425  DETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKI 484

Query: 1095 RKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR- 1146
               +P  L + ++GE+ ++L+Y+P    PV G +  +     GE+ +W+KE  +L   + 
Sbjct: 485  SAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKA 543

Query: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
            G   +SFVK  +LP  ++ S++KT  + KT NP +NHT VY+G R EDL   C+ELTVWD
Sbjct: 544  GGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWD 603

Query: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
               L +N FLGG+R+G GTG S G  VDWMDST EEV+LW+KM   P +W E TL LR
Sbjct: 604  REPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  260 bits (664), Expect = 7e-69
 Identities = 157/399 (39%), Positives = 232/399 (58%), Gaps = 42/399 (10%)

Query: 892  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVS 950
            D +   SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+ 
Sbjct: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM- 391

Query: 951  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 1008
               MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK
Sbjct: 392  ---MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVK 448

Query: 1009 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 1068
            +YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFL
Sbjct: 449  SYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFL 507

Query: 1069 GEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--------- 1117
            GEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         
Sbjct: 508  GEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLP 563

Query: 1118 PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRK 1165
            PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ 
Sbjct: 564  PEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKA 623

Query: 1166 SRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT 1224
            ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+
Sbjct: 624  TKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGS 683

Query: 1225 GKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
            G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 684  GVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  260 bits (664), Expect = 7e-69
 Identities = 157/399 (39%), Positives = 232/399 (58%), Gaps = 42/399 (10%)

Query: 892  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVS 950
            D +   SKSVP  L  +S ++ E    +  S QLS      ++   L+S    TSL+S+ 
Sbjct: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLS------TNTHRLASGLSTTSLNSM- 391

Query: 951  GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 1008
               MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  D KKQR+D YVK
Sbjct: 392  ---MSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVK 448

Query: 1009 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 1068
            +YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+WH D F RNSFL
Sbjct: 449  SYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFL 507

Query: 1069 GEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLALQYV--------- 1117
            GEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L+Y+         
Sbjct: 508  GEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVLRYIPPEENLMLP 563

Query: 1118 PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRK 1165
            PE + G K           + + G + +++KE  +L  ++ G   +SFVK  +LPD S+ 
Sbjct: 564  PEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKA 623

Query: 1166 SRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGT 1224
            ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N FLGG+R+  G+
Sbjct: 624  TKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGS 683

Query: 1225 GKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
            G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 684  GVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 722


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  258 bits (659), Expect = 3e-68
 Identities = 157/411 (38%), Positives = 234/411 (56%), Gaps = 44/411 (10%)

Query: 892  DKLKRMSKSVPAFLQDES-DDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMT------ 944
            D +   SKSVP  L  +S ++ E    +  S QLS +    +S  + SS +G        
Sbjct: 339  DTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYL 398

Query: 945  ------SLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAA 996
                  S ++   S+MSVYS  GD+GN++V G I   I Y      L++FV  C++LA  
Sbjct: 399  NVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIG 458

Query: 997  DVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSI 1056
            D KKQR+D YVK+YLLPDK +  K+KT +   T NP +NE L+Y I    L+T+ L LS+
Sbjct: 459  DEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSV 517

Query: 1057 WHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT--APVALEAENRGEMKLAL 1114
            WH D F RNSFLGEVE+  ++W+++N  ++   W+ L+ K   AP  +  + +GE+ + L
Sbjct: 518  WHYDRFGRNSFLGEVEIPFDSWNFENPTDE---WFVLQPKVEFAP-DIGLQYKGELTVVL 573

Query: 1115 QYV---------PEPVPGKK-----------LPTTGEVHIWVKECLDLPLLR-GSHLNSF 1153
            +Y+         PE + G K           + + G + +++KE  +L  ++ G   +SF
Sbjct: 574  RYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSF 633

Query: 1154 VKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TN 1212
            VK  +LPD S+ ++ KT  + K+ NP +NHT ++ G  P+D+   C+ELT+WD     +N
Sbjct: 634  VKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSN 693

Query: 1213 QFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
             FLGG+R+  G+G S+G  VDWMDS  EE  LW+KM N+P T  E  L LR
Sbjct: 694  IFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLR 744


>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
          Length = 542

 Score =  195 bits (495), Expect = 3e-49
 Identities = 124/348 (35%), Positives = 188/348 (54%), Gaps = 27/348 (7%)

Query: 936  NLSSSSGMTSLSSVS---GSVMSVYS-----GDFGNLEVKGNIQFAIEYVESLKELHVFV 987
            NL SS   +++ S     GS++S+ S     G+F N  V G I+FAI Y      L + +
Sbjct: 200  NLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICI 259

Query: 988  AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 1047
              CK+LA  + KK++ +PYVK YLLPD+   GK+KT V + T++P + E L+Y++    L
Sbjct: 260  KACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQL 319

Query: 1048 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEA-EN 1106
             T++L +S+WH  T  R  FLGEV + L TWD+++   +  RW+PL+ K         ++
Sbjct: 320  VTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQS 379

Query: 1107 RGEM----KLALQYVP----EPVPGKKLPTT-GEVHIWVKECLDLPLLRGSHLNSFVK-C 1156
             GE+    KL L   P    E   G   P+  G++ + V    +LP+     LNSFVK C
Sbjct: 380  NGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGC 439

Query: 1157 TILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH--YKLTNQF 1214
              LPD  +K R K+  + K   P + H+ V+ G  P  L ++ +ELTVWD   + + ++ 
Sbjct: 440  LTLPD-QQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRL 498

Query: 1215 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPL 1262
            LGG R+G     S G      D+ S     W+K+++SPN W + TL L
Sbjct: 499  LGGTRLG-----SKGDTAVGGDACSLSKLQWQKVLSSPNLWTDMTLVL 541


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  115 bits (289), Expect = 2e-25
 Identities = 110/423 (26%), Positives = 194/423 (45%), Gaps = 45/423 (10%)

Query: 832  KSLEDISSDSSNQAKVDNQPEELVRSAEDDE-KPDQKPVTNECVPRISTVPTQPDNPFSH 890
            KS    S+ ++    + + P E+  + E  E K ++KP      P I    T PD P   
Sbjct: 85   KSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAVKAIEPAIKISHTSPDIPAEV 144

Query: 891  PDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGM------- 943
               LK     +            T +   SS++  RH      ++++  S G        
Sbjct: 145  QTALKE--HLIKHARVQRQITEPTSSTRHSSFR--RHLPRQMQVSSVDFSMGTEPVLQRG 200

Query: 944  ---TSLSSVSGSVMSVYSGDF-GN----LEVKGNIQFAIEYVESLKELHVFVAQCKDLAA 995
               TS+  +   +    S D  GN    +++ G + F ++Y    + L V + +  DL A
Sbjct: 201  ETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPA 260

Query: 996  ADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLS 1055
             D     SDPYVK YLLPD+ K  K +T V +KTLNP+++E  ++ +    L  +KL+ S
Sbjct: 261  KDFTGT-SDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFS 317

Query: 1056 IWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQ 1115
            ++  D F R+  +GEV LD   ++  +   +   W  +   T     E+ + GE+  +L 
Sbjct: 318  VYDFDRFSRHDMIGEVILD-NLFEVSDLSREATVWKDIHCATT----ESIDLGEIMFSLC 372

Query: 1116 YVPEPVPGKKLPTTGEVHIWVKECLDLPL--LRGSHLNSFVKCTILPDTSRKSRQKTRAV 1173
            Y         LPT G + + V +C +L    + GS  + +VK +++ +  R  ++KT   
Sbjct: 373  Y---------LPTAGRMTLTVIKCRNLKAMDITGSS-DPYVKVSLMCEGRRLKKRKTTTK 422

Query: 1174 GKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGF---GTGKSYG 1229
              T NP++N  +++D   PE++ +  + + V D+ ++  N+ +G  R G    G G+ + 
Sbjct: 423  KNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHW 481

Query: 1230 TEV 1232
             E+
Sbjct: 482  NEM 484


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  115 bits (287), Expect = 3e-25
 Identities = 116/462 (25%), Positives = 210/462 (45%), Gaps = 52/462 (11%)

Query: 804  WRNP-SSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE 862
            WRN  +SS    +P L+ L+  + R   +  L+D S+    +A V     ++  ++ D  
Sbjct: 3    WRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAV-----KISHTSPDIP 57

Query: 863  KPDQKPVTNECV--PRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASES 920
               Q  V    +   R+    T+P +   H    + + + +     D  +  E   A+E 
Sbjct: 58   AEVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGN--ELPPAAEQ 115

Query: 921  SYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESL 980
               + R K     L    S  G  + S  + S               G I F++ Y    
Sbjct: 116  PTSIGRIKPE---LYKQKSVDGEDAKSEATKSC--------------GKINFSLRYDYET 158

Query: 981  KELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRY 1040
            + L V + +  DL A D     SDPYVK YLLPD+    K +T V +KTLNP ++E   +
Sbjct: 159  ETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHRKTLNPTFDENFHF 215

Query: 1041 KIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPV 1100
             +  + L  +KL+LS++  D F R+  +GEV LD   ++  +   +   W  ++  T+  
Sbjct: 216  PVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWKDIQYATS-- 272

Query: 1101 ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 1159
              E+ + GE+  +L Y         LPT G + + V +C +L  +    + + +VK ++L
Sbjct: 273  --ESVDLGEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLL 321

Query: 1160 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 1218
             D  R  ++KT     T NP++N  +++D   PE++ +  + ++V D+ ++  N+ +G  
Sbjct: 322  CDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMDYDRVGHNEIIGVC 380

Query: 1219 RIGF---GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 1257
            R+G    G G+ +  E+  +    + +A W  +V    ++ E
Sbjct: 381  RVGITAEGLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 3e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 958  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 1017
            SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291  SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 1018 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 1075
              K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350  --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 1076 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 1135
            E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408  ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 1136 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 1194
            + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452  IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 1195 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 1249
            +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511  VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 3e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 958  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 1017
            SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291  SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 1018 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 1075
              K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350  --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 1076 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 1135
            E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408  ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 1136 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 1194
            + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452  IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 1195 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 1249
            +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511  VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  112 bits (279), Expect = 3e-24
 Identities = 88/298 (29%), Positives = 145/298 (48%), Gaps = 26/298 (8%)

Query: 958  SGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGK 1017
            SG+ G     G I FA+ Y+    +L V + Q  DL A D     SDPYVK YLLPD+ K
Sbjct: 291  SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKD-SNGFSDPYVKIYLLPDRKK 349

Query: 1018 MGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD--L 1075
              K +T V +KTLNPV+NE  ++ +    L  +KL+ S++  D F R+  +G+V LD  L
Sbjct: 350  --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLL 407

Query: 1076 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIW 1135
            E  +    +       PL R       E  + GE+  +L Y         LPT G + + 
Sbjct: 408  ELAEQPPDR-------PLWRDIVEGGSEKADLGELNFSLCY---------LPTAGRLTVT 451

Query: 1136 VKECLDLPLLRGSHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPED 1194
            + +  +L  +  +  +  +VK +++ +  R  ++KT     T NP +N  +V+D   PE 
Sbjct: 452  IIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFD-VAPES 510

Query: 1195 LMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTE--VDWMDSTSEEVALWEKMV 1249
            +    + + V D+  +  N+ +G  R+G      +G E   + + +  + V  W ++V
Sbjct: 511  VENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLV 568


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 9e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141  GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198  KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 1146
              W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257  --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
            G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303  GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 1260
            + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362  YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 965  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 1024
            E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269  EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 1025 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 1077
            V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328  VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 1078 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 1107
            W     N +    +W+ LK +    AL  +N+
Sbjct: 388  WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  110 bits (275), Expect = 9e-24
 Identities = 89/299 (29%), Positives = 150/299 (50%), Gaps = 30/299 (10%)

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G +QF+++Y     +L V V Q  +L A D+    SDPYVK +LLPDK K  K +T V +
Sbjct: 141  GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNP +NE   +K+  Q L  + L ++I+  D F ++  +GEV++ + T D      + 
Sbjct: 198  KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE- 256

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR- 1146
              W  L+        E E  G++  +L+YV         PT G++ + + E  +L  +  
Sbjct: 257  --WRDLQGGEKE---EPEKLGDICTSLRYV---------PTAGKLTVCILEAKNLKKMDV 302

Query: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
            G   + +VK  ++ +  R  ++KT    KT NP FN +  ++    E + +  V +TV D
Sbjct: 303  GGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLD 361

Query: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEV----DWMDSTSEEVALWEKMVNSPNTWIEATL 1260
            + KL  N+ +G + +G     + GTE+    D + +    +A W  +   P   ++A L
Sbjct: 362  YDKLGKNEAIGKIFVG---SNATGTELRHWSDMLANPRRPIAQWHSL--KPEEEVDALL 415



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 10/152 (6%)

Query: 965  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 1024
            E  G+I  ++ YV +  +L V + + K+L   DV    SDPYVK +L+ +  ++ KKKT 
Sbjct: 269  EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL-SDPYVKIHLMQNGKRLKKKKTT 327

Query: 1025 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVEL-------DLET 1077
            V KKTLNP +NE   ++I  + ++  ++ +++   D   +N  +G++ +       +L  
Sbjct: 328  VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRH 387

Query: 1078 WD--WDNKQNKQLRWYPLKRKTAPVALEAENR 1107
            W     N +    +W+ LK +    AL  +N+
Sbjct: 388  WSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  107 bits (268), Expect = 6e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 394  GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 452

Query: 1028 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 1086
             T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 453  NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512

Query: 1087 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 1128
             +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 513  NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 563

Query: 1129 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 1187
             G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 564  QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 623

Query: 1188 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 1245
            D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 624  D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 682

Query: 1246 EKMVN 1250
             ++ N
Sbjct: 683  HQLQN 687



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 962  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 1021
            G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 546  GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 604

Query: 1022 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 1074
            KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 605  KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 664

Query: 1075 LETW--DWDNKQNKQLRWYPLKRK 1096
            L+ W     NK  K  RW+ L+ +
Sbjct: 665  LKHWYECLKNKDKKIERWHQLQNE 688


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  107 bits (268), Expect = 6e-23
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G ++F++ Y +    L   + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 390  GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448

Query: 1028 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 1086
             T NP++NE L Y  I  + ++ + L +S+   D F  N F+GE    L+    + ++N 
Sbjct: 449  NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508

Query: 1087 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 1128
             +   R  P+KR         +AL          + E RG++ ++L Y  +         
Sbjct: 509  NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559

Query: 1129 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 1187
             G + + +  C+ L  +    + + FVK  + PD  +K++ KT+   KT NP FN    Y
Sbjct: 560  QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619

Query: 1188 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 1245
            D  +  DL +  ++++VWD+    +N ++GG ++G    G+      + + +  +++  W
Sbjct: 620  D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678

Query: 1246 EKMVN 1250
             ++ N
Sbjct: 679  HQLQN 683



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)

Query: 962  GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 1021
            G++E +G I  ++ Y      L V + +C  LAA D     SDP+VK +L PD GK  K 
Sbjct: 542  GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600

Query: 1022 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 1074
            KT + KKTLNP +NE   Y I+   L  + L++S+W  D  K N ++G  +L        
Sbjct: 601  KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660

Query: 1075 LETW--DWDNKQNKQLRWYPLKRK 1096
            L+ W     NK  K  RW+ L+ +
Sbjct: 661  LKHWYECLKNKDKKIERWHQLQNE 684


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  107 bits (266), Expect = 9e-23
 Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 23/291 (7%)

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G + F++ Y +    LH  + + K L   D     +DPYVK +LLP   K  K +T  ++
Sbjct: 128  GTLDFSLLYDQENNALHCTITKAKGLKPMD-HNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 1028 KTLNPVYNEILR-YKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 1086
             TLNP +NE L  Y I  + +  + L +S+   D F+ N F+GE  + L+      K N 
Sbjct: 187  NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKL----KPNH 242

Query: 1087 QLRWYPLKRKTAPV----ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDL 1142
               +     K  PV        E RG + ++L+Y  +            + + +  C  L
Sbjct: 243  TKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQ---------KQGLLVGIVRCAHL 293

Query: 1143 PLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVE 1201
              +    + + +VK  + PD  +KS+ KT    KT NP FN    Y+  +  DL +  +E
Sbjct: 294  AAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLE 352

Query: 1202 LTVWDH-YKLTNQFLGGLRIGF-GTGKSYGTEVDWMDSTSEEVALWEKMVN 1250
            +TVWD+    +N F+GG+ +G    G+      D + +  + +  W  + +
Sbjct: 353  VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTS 403



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 963  NLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKK 1022
            +LE +G I  +++Y    + L V + +C  LAA D     SDPYVK YL PD  K  K K
Sbjct: 263  SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKKSKHK 321

Query: 1023 TLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD-------L 1075
            T V KKTLNP +NE   Y+I+   L  + L +++W  D  K N F+G V L        L
Sbjct: 322  TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERL 381

Query: 1076 ETW--DWDNKQNKQLRWYPL 1093
            + W     NK  +  RW+ L
Sbjct: 382  KHWFDCLKNKDKRIERWHTL 401


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 3e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 965  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 1024
            E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141  EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 1025 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 1084
            V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198  VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 1085 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 1144
             +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258  EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 1145 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 1203
            +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303  MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 1204 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 1252
            V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362  VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 3e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 965  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 1024
            E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141  EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 1025 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 1084
            V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198  VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 1085 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 1144
             +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258  EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 1145 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 1203
            +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303  MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 1204 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 1252
            V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362  VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 3e-21
 Identities = 80/290 (27%), Positives = 144/290 (49%), Gaps = 34/290 (11%)

Query: 965  EVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTL 1024
            E  G +Q++++Y     +L V + Q  +L A D+    SDPYVK +LLPDK K  K +T 
Sbjct: 141  EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETK 197

Query: 1025 VVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQ 1084
            V +KTLNPV+NE   +K+    L  + L ++++  D F ++  +GE ++ + T D+ +  
Sbjct: 198  VHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVT 257

Query: 1085 NKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPL 1144
             +   W  L+        E E  G++  +L+YV         PT G++ + + E  +L  
Sbjct: 258  EE---WRDLQSAEKE---EQEKLGDICFSLRYV---------PTAGKLTVVILEAKNLKK 302

Query: 1145 LR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELT 1203
            +  G   + +VK  ++ +  R  ++KT     T NP +N +  ++    E + +  V +T
Sbjct: 303  MDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVT 361

Query: 1204 VWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSP 1252
            V D+ K+  N  +G + +G+             +ST  E+  W  M+ +P
Sbjct: 362  VLDYDKIGKNDAIGKVFVGY-------------NSTGAELRHWSDMLANP 398


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  101 bits (252), Expect = 4e-21
 Identities = 86/347 (24%), Positives = 169/347 (48%), Gaps = 31/347 (8%)

Query: 914  TDTASESSYQLSRHKKSPS-SLTNLSSSSGMTSLSSVSGSVMSVYS-----GDFGNLEVK 967
            T +A  +S +   +  +P  ++  L     +T +  +   +    S     G   N +  
Sbjct: 162  TSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKAC 221

Query: 968  GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 1027
            G + F ++Y   L++L V + +  +L A D     SDPYVK YLLPD+    K +T V +
Sbjct: 222  GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKT--KHQTKVHR 278

Query: 1028 KTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQ 1087
            KTLNPV++E+  + +    L+ +KL+ S++  D F R+  +G+V +D    D  +   + 
Sbjct: 279  KTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD-HFLDLADFPREC 337

Query: 1088 LRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRG 1147
            + W  ++     V  +  + GE+  +L Y         LPT G + I + +  +L  +  
Sbjct: 338  ILWKDIEY----VTNDNVDLGELMFSLCY---------LPTAGRLTITIIKARNLKAMDI 384

Query: 1148 SHLNS-FVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
            +  +  +VK +++ D  R  ++KT     T NP++N  +V+D   PE++ +  + + V D
Sbjct: 385  TGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFD-VPPENIDQIHLSIAVMD 443

Query: 1207 HYKL-TNQFLGGLRIGFGT---GKSYGTEVDWMDSTSEEVALWEKMV 1249
            + ++  N+ +G  ++G      G+ + +E+  +    + +A W  +V
Sbjct: 444  YDRVGHNEIIGVCQVGNEAERLGRDHWSEM--LSYPRKPIAHWHSLV 488


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,012,931
Number of Sequences: 37866
Number of extensions: 2509748
Number of successful extensions: 9724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 365
Number of HSP's that attempted gapping in prelim test: 8377
Number of HSP's gapped (non-prelim): 1363
length of query: 1272
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1158
effective length of database: 13,930,794
effective search space: 16131859452
effective search space used: 16131859452
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.