Search of human proteins with 46255032

Search of human proteins with 46255032

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255032 family with sequence similarity 3, member B isoform
b [Homo sapiens]
         (187 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46255032 family with sequence similarity 3, member B isoform ...   387   e-108
gi|46255030 family with sequence similarity 3, member B isoform ...   379   e-106
gi|91807125 family with sequence similarity 3, member C precurso...   147   4e-36
gi|7661714 family with sequence similarity 3, member C precursor...   147   4e-36
gi|13324682 family 3, member A protein [Homo sapiens]                 139   2e-33
gi|20270363 family with sequence similarity 3, member D [Homo sa...   133   1e-31
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    64   6e-11
gi|38638698 KIAA1199 [Homo sapiens]                                    49   3e-06
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]          37   0.008
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]            37   0.008
gi|223633991 vanin 1 precursor [Homo sapiens]                          30   1.6  
gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]           27   7.9  
gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens]           27   7.9  
gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo sap...    27   7.9  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    27   7.9  

>gi|46255032 family with sequence similarity 3, member B isoform b
           [Homo sapiens]
          Length = 187

 Score =  387 bits (994), Expect = e-108
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MRPLAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARG 60
           MRPLAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARG
Sbjct: 1   MRPLAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARG 60

Query: 61  INIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAK 120
           INIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAK
Sbjct: 61  INIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAK 120

Query: 121 NAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEG 180
           NAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEG
Sbjct: 121 NAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEG 180

Query: 181 CIPKERS 187
           CIPKERS
Sbjct: 181 CIPKERS 187


>gi|46255030 family with sequence similarity 3, member B isoform a
           [Homo sapiens]
          Length = 235

 Score =  379 bits (973), Expect = e-106
 Identities = 183/186 (98%), Positives = 184/186 (98%)

Query: 2   RPLAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI 61
           RP+  APVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI
Sbjct: 50  RPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI 109

Query: 62  NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN 121
           NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN
Sbjct: 110 NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN 169

Query: 122 AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC 181
           AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC
Sbjct: 170 AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC 229

Query: 182 IPKERS 187
           IPKERS
Sbjct: 230 IPKERS 235


>gi|91807125 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  147 bits (372), Expect = 4e-36
 Identities = 72/177 (40%), Positives = 107/177 (60%), Gaps = 3/177 (1%)

Query: 10  PKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYV 69
           P R KC     CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  
Sbjct: 53  PPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGK 112

Query: 70  TGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSK 129
           TG V  T+ FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS 
Sbjct: 113 TGEVLDTKYFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGST 171

Query: 130 EIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 186
            I N+ FR +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 172 SITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226


>gi|7661714 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  147 bits (372), Expect = 4e-36
 Identities = 72/177 (40%), Positives = 107/177 (60%), Gaps = 3/177 (1%)

Query: 10  PKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYV 69
           P R KC     CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  
Sbjct: 53  PPRYKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGK 112

Query: 70  TGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSK 129
           TG V  T+ FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS 
Sbjct: 113 TGEVLDTKYFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGST 171

Query: 130 EIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 186
            I N+ FR +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 172 SITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226


>gi|13324682 family 3, member A protein [Homo sapiens]
          Length = 230

 Score =  139 bits (349), Expect = 2e-33
 Identities = 68/181 (37%), Positives = 106/181 (58%), Gaps = 3/181 (1%)

Query: 4   LAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINI 63
           +  AP  ++ KC    PCP +  A+R++SG       KIC ED +LM     NV RG+NI
Sbjct: 48  VTAAPRARKYKCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNI 107

Query: 64  AIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAI 123
           A+VN V+G +   R FDM+ GD    + KFI+     +L+F+ +YDD +T++N + +   
Sbjct: 108 ALVNGVSGELIEARAFDMWAGD-VNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLF 166

Query: 124 EALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIP 183
             LGS+  + + FR SWVF+ AKG++  S  ++   N     +N+Y G P  +++EGCIP
Sbjct: 167 SELGSRNAKELAFRDSWVFVGAKGVQNKSPFEQHVKN--SKHSNKYEGCPEALEMEGCIP 224

Query: 184 K 184
           +
Sbjct: 225 R 225


>gi|20270363 family with sequence similarity 3, member D [Homo
           sapiens]
          Length = 224

 Score =  133 bits (334), Expect = 1e-31
 Identities = 69/186 (37%), Positives = 105/186 (56%), Gaps = 7/186 (3%)

Query: 2   RPLAGAPVP----KRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNV 57
           R LA +P      K+ KC    PCP++ +A+++ SG        +CFED ++M     NV
Sbjct: 38  RWLAASPTKEIQVKKYKCGLIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNV 97

Query: 58  ARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNN 117
            RG+NIA+VN  TG V   + FDMY GD    + KF++     +L+ + +YDD  T++N+
Sbjct: 98  GRGLNIALVNGTTGAVLGQKAFDMYSGDVM-HLVKFLKEIPGGALVLVASYDDPGTKMND 156

Query: 118 DAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQ 177
           +++     LGS   + + FR SWVFI AK L   S  ++   N  D   N+Y GWP  ++
Sbjct: 157 ESRKLFSDLGSSYAKQLGFRDSWVFIGAKDLRGKSPFEQFLKNSPD--TNKYEGWPELLE 214

Query: 178 IEGCIP 183
           +EGC+P
Sbjct: 215 MEGCMP 220


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 64.3 bits (155), Expect = 6e-11
 Identities = 31/106 (29%), Positives = 53/106 (50%)

Query: 42  ICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKS 101
           +  +   ++ ++     RGI++ ++N  TG+V A R FD Y       M  F+   AP  
Sbjct: 112 VAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGR 171

Query: 102 LLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKG 147
           +L     D+GS  L + AK  + +LGS+    + +R +W F+  KG
Sbjct: 172 VLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKG 217


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 1/90 (1%)

Query: 59  RGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLNN 117
           RG+ + +++  +G V  +  FD Y     S  + +++ +     +L +   D+GS  L++
Sbjct: 187 RGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDD 246

Query: 118 DAKNAIEALGSKEIRNMKFRSSWVFIAAKG 147
            A+ A+  LGSK   ++ FR  W F+  KG
Sbjct: 247 MARKAMTKLGSKHFLHLGFRHPWSFLTVKG 276


>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
          Length = 1320

 Score = 37.4 bits (85), Expect = 0.008
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 58  ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323

Query: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372


>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
          Length = 1383

 Score = 37.4 bits (85), Expect = 0.008
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 58  ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 116
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323

Query: 117 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 162
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372


>gi|223633991 vanin 1 precursor [Homo sapiens]
          Length = 513

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 3/89 (3%)

Query: 7   APVPKRQKCDHWTP-CPSD-TYAYRL-LSGGGRSKYAKICFEDNLLMGEQLGNVARGINI 63
           A +  ++ CD   P CP D  Y Y   +    + K      + NL MGE   NV +   I
Sbjct: 137 ANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGENQFNVPKEPEI 196

Query: 64  AIVNYVTGNVTATRCFDMYEGDNSGPMTK 92
              N   G+     CFD+   D +  + K
Sbjct: 197 VTFNTTFGSFGIFTCFDILFHDPAVTLVK 225


>gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]
          Length = 541

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 7/59 (11%)

Query: 54  LGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVT-YDDG 111
           LG   R   +    Y+ G V      D  +GD+ GP+T       P+ +LF VT + DG
Sbjct: 197 LGPGLRPSTMLCAGYLAGGV------DSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDG 249


>gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens]
          Length = 541

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 7/59 (11%)

Query: 54  LGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVT-YDDG 111
           LG   R   +    Y+ G V      D  +GD+ GP+T       P+ +LF VT + DG
Sbjct: 197 LGPGLRPSTMLCAGYLAGGV------DSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDG 249


>gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo
           sapiens]
          Length = 541

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 7/59 (11%)

Query: 54  LGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVT-YDDG 111
           LG   R   +    Y+ G V      D  +GD+ GP+T       P+ +LF VT + DG
Sbjct: 197 LGPGLRPSTMLCAGYLAGGV------DSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDG 249


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta
           [Homo sapiens]
          Length = 1983

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 18/81 (22%), Positives = 38/81 (46%)

Query: 100 KSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKI 159
           K LL     ++    L  + +    AL + E +  +   + V I  +  +L  ++Q E+ 
Sbjct: 886 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 945

Query: 160 NHSDAKNNRYSGWPAEIQIEG 180
           N +DA+   +    +++Q+EG
Sbjct: 946 NLADAEERCHLLIKSKVQLEG 966


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,201,412
Number of Sequences: 37866
Number of extensions: 300495
Number of successful extensions: 553
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 15
length of query: 187
length of database: 18,247,518
effective HSP length: 96
effective length of query: 91
effective length of database: 14,612,382
effective search space: 1329726762
effective search space used: 1329726762
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.