Search of human proteins with 46094058

Search of human proteins with 46094058

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46094058 3'-phosphoadenosine 5'-phosphosulfate synthase 1
[Homo sapiens]
         (624 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46094058 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Ho...  1293   0.0  
gi|34447231 3'-phosphoadenosine 5'-phosphosulfate synthase 2 iso...  1011   0.0  
gi|62912492 3'-phosphoadenosine 5'-phosphosulfate synthase 2 iso...  1008   0.0  
gi|14150100 nucleoside-triphosphatase C1orf57 [Homo sapiens]           32   1.3  
gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sa...    31   3.0  
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...    31   3.9  
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...    31   3.9  
gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]          31   3.9  
gi|6631095 minichromosome maintenance complex component 3 [Homo ...    31   3.9  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]       30   8.7  
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]        30   8.7  

>gi|46094058 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Homo
           sapiens]
          Length = 624

 Score = 1293 bits (3347), Expect = 0.0
 Identities = 624/624 (100%), Positives = 624/624 (100%)

Query: 1   MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60
           MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL
Sbjct: 1   MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL 60

Query: 61  SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120
           SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF
Sbjct: 61  SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF 120

Query: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180
           ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG
Sbjct: 121 ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG 180

Query: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240
           EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP
Sbjct: 181 EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP 240

Query: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300
           ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG
Sbjct: 241 ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG 300

Query: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360
           VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC
Sbjct: 301 VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC 360

Query: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL 420
           KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL
Sbjct: 361 KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL 420

Query: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480
           RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV
Sbjct: 421 RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV 480

Query: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540
           LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS
Sbjct: 481 LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS 540

Query: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600
           HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK
Sbjct: 541 HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK 600

Query: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624
           PPEGFMAPKAWTVLTEYYKSLEKA
Sbjct: 601 PPEGFMAPKAWTVLTEYYKSLEKA 624


>gi|34447231 3'-phosphoadenosine 5'-phosphosulfate synthase 2
           isoform a [Homo sapiens]
          Length = 614

 Score = 1011 bits (2615), Expect = 0.0
 Identities = 475/615 (77%), Positives = 542/615 (88%), Gaps = 6/615 (0%)

Query: 9   KKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTV 68
           KK K  N       Q++TNV YQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTT+
Sbjct: 5   KKQKTENQ------QKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTI 58

Query: 69  SMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCI 128
           S ALEEYLV H IPCY+LDGDN+R GLN+NLGFSP DREEN+RRIAEVAKLFADAGLVCI
Sbjct: 59  SFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCI 118

Query: 129 TSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGI 188
           TSFISP+ +DR NAR+IHE A LPFFE+FVDAPL++CE RDVKGLYK+ARAGEIKGFTGI
Sbjct: 119 TSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGI 178

Query: 189 DSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVPENKLHLAK 248
           DS+YEKPE PE VLKT+   V+DCV QVVELLQE++IVP     ++ EL+VPENKL   +
Sbjct: 179 DSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPYTIIKDIHELFVPENKLDHVR 238

Query: 249 TDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPI 308
            +AETLP+L I K+D+QWVQVL+EGWATPL GFMRE+EYLQ +HFD LLD GVIN+S+PI
Sbjct: 239 AEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLDDGVINMSIPI 298

Query: 309 VLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKM 368
           VL  + EDK RL+GC+ F L + GRRVAILR+ EF+EHRKEERC+R WGTTC  HP+IKM
Sbjct: 299 VLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKHPHIKM 358

Query: 369 VMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGH 428
           VME GDWL+GGDLQVL+++ WNDGLDQYRLTP ELKQK K+MNADAVFAFQLRNPVHNGH
Sbjct: 359 VMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVHNGH 418

Query: 429 ALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNPETTVV 488
           ALLMQDT ++LLERGY+ PVLLLHPLGGWTKDDDVPL WRMKQHAAVLEEGVL+P++T+V
Sbjct: 419 ALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIV 478

Query: 489 AIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGAKVLTM 548
           AIFPSPM+YAGPTEVQWHCR+RM+AGANFYIVGRDPAGMPHPET KDLYEP+HG KVL+M
Sbjct: 479 AIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKKDLYEPTHGGKVLSM 538

Query: 549 APGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAP 608
           APGL ++EI+PFRVAAYNK KK MD+YD   H +F+FISGTRMRKLAREG+ PP+GFMAP
Sbjct: 539 APGLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAP 598

Query: 609 KAWTVLTEYYKSLEK 623
           KAW VLT+YY+SLEK
Sbjct: 599 KAWKVLTDYYRSLEK 613


>gi|62912492 3'-phosphoadenosine 5'-phosphosulfate synthase 2
           isoform b [Homo sapiens]
          Length = 619

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 476/620 (76%), Positives = 543/620 (87%), Gaps = 11/620 (1%)

Query: 9   KKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTV 68
           KK K  N       Q++TNV YQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTT+
Sbjct: 5   KKQKTENQ------QKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTI 58

Query: 69  SMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCI 128
           S ALEEYLV H IPCY+LDGDN+R GLN+NLGFSP DREEN+RRIAEVAKLFADAGLVCI
Sbjct: 59  SFALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCI 118

Query: 129 TSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGI 188
           TSFISP+ +DR NAR+IHE A LPFFE+FVDAPL++CE RDVKGLYK+ARAGEIKGFTGI
Sbjct: 119 TSFISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGI 178

Query: 189 DSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVPENKLHLAK 248
           DS+YEKPE PE VLKT+   V+DCV QVVELLQE++IVP     ++ EL+VPENKL   +
Sbjct: 179 DSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPYTIIKDIHELFVPENKLDHVR 238

Query: 249 TDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDG-----GVIN 303
            +AETLP+L I K+D+QWVQVL+EGWATPL GFMRE+EYLQ +HFD LLDG     GVIN
Sbjct: 239 AEAETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLDGMALPDGVIN 298

Query: 304 LSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNH 363
           +S+PIVL  + EDK RL+GC+ F L + GRRVAILR+ EF+EHRKEERC+R WGTTC  H
Sbjct: 299 MSIPIVLPVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKH 358

Query: 364 PYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNP 423
           P+IKMVME GDWL+GGDLQVL+++ WNDGLDQYRLTP ELKQK K+MNADAVFAFQLRNP
Sbjct: 359 PHIKMVMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNP 418

Query: 424 VHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGVLNP 483
           VHNGHALLMQDT ++LLERGY+ PVLLLHPLGGWTKDDDVPL WRMKQHAAVLEEGVL+P
Sbjct: 419 VHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDP 478

Query: 484 ETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPSHGA 543
           ++T+VAIFPSPM+YAGPTEVQWHCR+RM+AGANFYIVGRDPAGMPHPET KDLYEP+HG 
Sbjct: 479 KSTIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKKDLYEPTHGG 538

Query: 544 KVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPE 603
           KVL+MAPGL ++EI+PFRVAAYNK KK MD+YD   H +F+FISGTRMRKLAREG+ PP+
Sbjct: 539 KVLSMAPGLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPD 598

Query: 604 GFMAPKAWTVLTEYYKSLEK 623
           GFMAPKAW VLT+YY+SLEK
Sbjct: 599 GFMAPKAWKVLTDYYRSLEK 618


>gi|14150100 nucleoside-triphosphatase C1orf57 [Homo sapiens]
          Length = 190

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 55  VWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGF 101
           V+LTG  G GKTT+     E L   G+P      + +RQG  + +GF
Sbjct: 5   VFLTGPPGVGKTTLIHKASEVLKSSGVPVDGFYTEEVRQG-GRRIGF 50


>gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo
           sapiens]
          Length = 842

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 7/59 (11%)

Query: 52  GCTVWLTGLSGAGKTTV-SMALEEYLVCHGIPCYTLDGDNIRQ----GLNKNLGFSPED 105
           G T+ L G SGAGK+T+  +    Y +  G  C  +DG +I Q     L  ++G  P+D
Sbjct: 616 GQTLALVGPSGAGKSTILRLLFRFYDISSG--CIRIDGQDISQVTQASLRSHIGVVPQD 672


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 519 IVGRDPAGMPHPETGKDLYEPSHGAKVLTMAP------GLITLEIVP 559
           I G+ P+ MP P  GK++Y    G+  L  AP      G +  +I+P
Sbjct: 677 IHGKIPSEMPSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADIMP 723


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 6/47 (12%)

Query: 519 IVGRDPAGMPHPETGKDLYEPSHGAKVLTMAP------GLITLEIVP 559
           I G+ P+ MP P  GK++Y    G+  L  AP      G +  +I+P
Sbjct: 570 IHGKIPSEMPSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADIMP 616


>gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]
          Length = 229

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 2/40 (5%)

Query: 400 PTELKQKFKDMNADAVFAFQLRNPVHNGH--ALLMQDTHK 437
           PT+L QKF D ++  +F    +NP  N H  A+ M   HK
Sbjct: 159 PTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHK 198


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 17/59 (28%), Positives = 27/59 (45%)

Query: 105 DREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLH 163
           D+E   RR+   A + AD G+VCI  F      DR    ++ E   +   +  + A L+
Sbjct: 385 DQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLN 443


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 9/72 (12%)

Query: 291 LHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEE 350
           +  DCL+ GG    +V + +    ED  R      F L    R+V+ L+N         +
Sbjct: 788 MSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQN---------Q 838

Query: 351 RCARQWGTTCKN 362
           R  R W   C++
Sbjct: 839 RSQRSWRLACES 850


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 9/72 (12%)

Query: 291 LHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEE 350
           +  DCL+ GG    +V + +    ED  R      F L    R+V+ L+N         +
Sbjct: 787 MSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQN---------Q 837

Query: 351 RCARQWGTTCKN 362
           R  R W   C++
Sbjct: 838 RSQRSWRLACES 849


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,423,625
Number of Sequences: 37866
Number of extensions: 1191456
Number of successful extensions: 2455
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2447
Number of HSP's gapped (non-prelim): 11
length of query: 624
length of database: 18,247,518
effective HSP length: 108
effective length of query: 516
effective length of database: 14,157,990
effective search space: 7305522840
effective search space used: 7305522840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.