Guide to the Human Genome
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Search of human proteins with 13129068

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13129068 nucleolar complex associated 4 homolog [Homo
sapiens]
         (516 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13129068 nucleolar complex associated 4 homolog [Homo sapiens]    1036   0.0  
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]      50   4e-06
gi|42542392 CCAAT/enhancer binding protein zeta [Homo sapiens]         40   0.005
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s...    32   1.8  
gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo s...    32   1.8  
gi|146198864 potassium channel tetramerisation domain containing...    31   2.4  
gi|170763479 MMS19 nucleotide excision repair homolog [Homo sapi...    31   3.1  
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi...    30   4.1  
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi...    30   4.1  
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]     30   4.1  
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    30   6.9  
gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]           29   9.0  
gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens]          29   9.0  
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          29   9.0  

>gi|13129068 nucleolar complex associated 4 homolog [Homo sapiens]
          Length = 516

 Score = 1036 bits (2679), Expect = 0.0
 Identities = 516/516 (100%), Positives = 516/516 (100%)

Query: 1   MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQSEDQEEIQEAVRTCSRLFGAL 60
           MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQSEDQEEIQEAVRTCSRLFGAL
Sbjct: 1   MEREPGAAGVRRALGRRLEAVLASRSEANAVFDILAVLQSEDQEEIQEAVRTCSRLFGAL 60

Query: 61  LERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALS 120
           LERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALS
Sbjct: 61  LERGELFVGQLPSEEMVMTGSQGATRKYKVWMRHRYHSCCNRLGELLGHPSFQVKELALS 120

Query: 121 ALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSPEEDQSLLLSQFREYLDYDDT 180
           ALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSPEEDQSLLLSQFREYLDYDDT
Sbjct: 121 ALLKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSPEEDQSLLLSQFREYLDYDDT 180

Query: 181 RYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTW 240
           RYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTW
Sbjct: 181 RYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTW 240

Query: 241 KVAHLKEHRRVFQAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDL 300
           KVAHLKEHRRVFQAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDL
Sbjct: 241 KVAHLKEHRRVFQAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDL 300

Query: 301 GGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHL 360
           GGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHL
Sbjct: 301 GGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHL 360

Query: 361 PAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDP 420
           PAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDP
Sbjct: 361 PAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDP 420

Query: 421 GEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFE 480
           GEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFE
Sbjct: 421 GEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYEIFE 480

Query: 481 RDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS 516
           RDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS
Sbjct: 481 RDLKKKGPEPVPLEFIPAQGLLGRPGELCAQHFTLS 516


>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
          Length = 800

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 5/116 (4%)

Query: 367 AFAKRLARLALTAPPEALLMVLPFICNLLRRHPACRVLVHRPHGPELDADPYDPGEEDPA 426
           AF KRL  LAL   P + + +L     L+   P   +L+         +  + P  ++P 
Sbjct: 625 AFIKRLCTLALHVLPNSSIGILATTRILMHTFPKTDLLLD---SESQGSGVFLPELDEPE 681

Query: 427 QSRALESSLWELQALQRHYHPEVSK-AASVINQALSMPEVSIAP-LLELTAYEIFE 480
              A  ++LWEL AL+RHYHP V + AA +I  A S    ++ P L   +A E+FE
Sbjct: 682 YCNAQNTALWELHALRRHYHPIVQRFAAHLIAGAPSEGSGALKPELSRRSATELFE 737


>gi|42542392 CCAAT/enhancer binding protein zeta [Homo sapiens]
          Length = 1054

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 418 YDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPEVSIAPLLELTAYE 477
           YDP   +P    A  +SLWEL+ L  H+HP V+  A  I Q  +  + S  PL + T   
Sbjct: 696 YDPFSRNPLFCGAENTSLWELKKLSVHFHPSVALFAKTILQG-NYIQYSGDPLQDFTLMR 754

Query: 478 IFERDLKKKGPEP 490
             +R    + P+P
Sbjct: 755 FLDR-FVYRNPKP 766


>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
           sapiens]
          Length = 1074

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 1/34 (2%)

Query: 408 PHGPELDADPYDPGEEDPAQSRALE-SSLWELQA 440
           PHGP L+ DP  PG   P  S     SSLW L A
Sbjct: 323 PHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFA 356


>gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo
           sapiens]
          Length = 877

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 1/34 (2%)

Query: 408 PHGPELDADPYDPGEEDPAQSRALE-SSLWELQA 440
           PHGP L+ DP  PG   P  S     SSLW L A
Sbjct: 323 PHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFA 356


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 102 RLGELLGHPSFQVKELALSALLKFVQLEGAHPLEKSKWEGNYLFPRE 148
           R GELL    F+  +L L+   +F QL+G     KS+WE   L PRE
Sbjct: 94  RNGELLLPEGFRENQL-LAQEAEFFQLKGLAEEVKSRWEKEQLTPRE 139


>gi|170763479 MMS19 nucleotide excision repair homolog [Homo
           sapiens]
          Length = 1030

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 394 LLRRHPACRVLVHRPHGPELDADPYDPG-EEDPAQSRALESSLWELQALQRHYHPEVSKA 452
           LL +HPA + L       +L  D  + G    P +S+A    LW  +AL   YHP  S  
Sbjct: 764 LLNKHPAGQQL---DEFLQLAVDKVEAGLGSGPCRSQAFTLLLWVTKALVLRYHPLSSCL 820

Query: 453 ASVINQALSMPEVSIA 468
            + +   LS PE+  A
Sbjct: 821 TARLMGLLSDPELGPA 836


>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
           sapiens]
          Length = 953

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 10/114 (8%)

Query: 291 IDFLTRACD----LGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRAR 346
           +D+L+   D     G  L L+ +  ++ + H +  E   F R +Y LL  S   VKY A 
Sbjct: 206 LDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEA- 264

Query: 347 FFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPA 400
               A   ++ S  P  + AA    +  +   +     L+VL  +   L+ HPA
Sbjct: 265 ----AGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIE-LKEHPA 313


>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
           sapiens]
          Length = 953

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 10/114 (8%)

Query: 291 IDFLTRACD----LGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRAR 346
           +D+L+   D     G  L L+ +  ++ + H +  E   F R +Y LL  S   VKY A 
Sbjct: 206 LDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEA- 264

Query: 347 FFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPA 400
               A   ++ S  P  + AA    +  +   +     L+VL  +   L+ HPA
Sbjct: 265 ----AGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIE-LKEHPA 313


>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
          Length = 953

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 10/114 (8%)

Query: 291 IDFLTRACD----LGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRAR 346
           +D+L+   D     G  L L+ +  ++ + H +  E   F R +Y LL  S   VKY A 
Sbjct: 206 LDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEA- 264

Query: 347 FFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPFICNLLRRHPA 400
               A   ++ S  P  + AA    +  +   +     L+VL  +   L+ HPA
Sbjct: 265 ----AGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIE-LKEHPA 313


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
            sapiens]
          Length = 2564

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 405  VHRPHGPELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALSMPE 464
            VH+     + AD +   +E   QSR L SS+ E++ L R  H    KAA+   +  S   
Sbjct: 2050 VHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRR-HEAFRKAAAAWEERFS--- 2105

Query: 465  VSIAPLLELTAYEIFERDLKKKGPEPVPLEFIPAQGLLGRPGELCAQ 511
                 L  LT  E  + +  K+ P P     +  +   G P EL A+
Sbjct: 2106 ----SLRRLTTIEKIKAEQSKQPPTP-----LLGRKFFGDPTELAAK 2143


>gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]
          Length = 347

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 14/122 (11%)

Query: 123 LKFVQLEGAHPLEKSKWEGNYLFPRELFKLVVGGLLSPEE--DQSLLLSQFREYLDYDDT 180
           + F+ LE  HP +  KW     F +E   L    L+   E  ++ LL+   R YL+    
Sbjct: 26  ITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKW 85

Query: 181 RYHTMQAAVDAVARVTGQHPEVPPAFWNNAFTLLSAVSLPRREPTVSSFYVKRAELWDTW 240
            +        AVA +T    E+PP  +   F +   V  P R  T  +    +  +   W
Sbjct: 86  SF--------AVATIT----EIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGW 133

Query: 241 KV 242
            +
Sbjct: 134 AI 135


>gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens]
          Length = 651

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/18 (72%), Positives = 15/18 (83%)

Query: 302 GALSLLALNGLFILIHKH 319
           GAL LLAL GL +L+HKH
Sbjct: 482 GALLLLALLGLAVLVHKH 499


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/18 (72%), Positives = 15/18 (83%)

Query: 302 GALSLLALNGLFILIHKH 319
           GAL LLAL GL +L+HKH
Sbjct: 676 GALLLLALLGLAVLVHKH 693


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,383,540
Number of Sequences: 37866
Number of extensions: 898585
Number of successful extensions: 2097
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2090
Number of HSP's gapped (non-prelim): 15
length of query: 516
length of database: 18,247,518
effective HSP length: 107
effective length of query: 409
effective length of database: 14,195,856
effective search space: 5806105104
effective search space used: 5806105104
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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