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Search of human proteins with 109255230
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109255230 centrosomal protein 170kDa isoform beta [Homo
sapiens]
(1486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 2920 0.0
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 2818 0.0
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 2310 0.0
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 347 4e-95
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 307 6e-83
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 77 2e-13
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 77 2e-13
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 77 2e-13
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 77 2e-13
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 76 2e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 67 2e-10
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 65 5e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 64 8e-10
gi|50083281 KIAA1853 protein [Homo sapiens] 61 7e-09
gi|212549782 caspase 8 associated protein 2 [Homo sapiens] 60 2e-08
gi|6912288 caspase 8 associated protein 2 [Homo sapiens] 60 2e-08
gi|212549532 caspase 8 associated protein 2 [Homo sapiens] 60 2e-08
gi|148746195 trichohyalin [Homo sapiens] 58 8e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 58 8e-08
gi|155722990 solute carrier family 4 (anion exchanger), member 1... 57 1e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 55 5e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 55 5e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 55 5e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 55 7e-07
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 55 7e-07
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 2920 bits (7569), Expect = 0.0
Identities = 1486/1486 (100%), Positives = 1486/1486 (100%)
Query: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
Query: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
Sbjct: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
Query: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
Sbjct: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
Query: 421 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 480
DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
Sbjct: 421 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 480
Query: 481 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 540
GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
Sbjct: 481 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 540
Query: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
Sbjct: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
Query: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
Sbjct: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
Query: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 720
WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
Sbjct: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 720
Query: 721 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 780
QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
Sbjct: 721 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 780
Query: 781 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 840
SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
Sbjct: 781 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 840
Query: 841 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 900
STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
Sbjct: 841 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 900
Query: 901 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 960
VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
Sbjct: 901 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 960
Query: 961 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 1020
SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
Sbjct: 961 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 1020
Query: 1021 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1080
ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
Sbjct: 1021 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1080
Query: 1081 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1140
RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA
Sbjct: 1081 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1140
Query: 1141 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1200
STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
Sbjct: 1141 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1200
Query: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV
Sbjct: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
Query: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL
Sbjct: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
Query: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ
Sbjct: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
Query: 1381 ELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQ 1440
ELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQ
Sbjct: 1381 ELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQ 1440
Query: 1441 PEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1486
PEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
Sbjct: 1441 PEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1486
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapiens]
Length = 1460
Score = 2818 bits (7305), Expect = 0.0
Identities = 1450/1496 (96%), Positives = 1450/1496 (96%), Gaps = 46/1496 (3%)
Query: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
Query: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
Sbjct: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
Query: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
Sbjct: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
Query: 421 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 480
DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS
Sbjct: 421 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 480
Query: 481 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 540
GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG
Sbjct: 481 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQG 540
Query: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL
Sbjct: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
Query: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ
Sbjct: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
Query: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 720
WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS
Sbjct: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 720
Query: 721 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 780
QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER
Sbjct: 721 QTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER 780
Query: 781 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 840
SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA
Sbjct: 781 SESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTA 840
Query: 841 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 900
STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD
Sbjct: 841 STISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD 900
Query: 901 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 960
VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT
Sbjct: 901 VGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLT 960
Query: 961 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 1020
SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD
Sbjct: 961 SADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELAD 1020
Query: 1021 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1080
ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS
Sbjct: 1021 ADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASS 1080
Query: 1081 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYA 1140
RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS
Sbjct: 1081 RTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS------------- 1127
Query: 1141 STSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1200
ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH
Sbjct: 1128 -----------------------ALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAH 1164
Query: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREE----- 1255
REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREE
Sbjct: 1165 REEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLH 1224
Query: 1256 -----LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1310
LVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR
Sbjct: 1225 GEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSR 1284
Query: 1311 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1370
DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT
Sbjct: 1285 DEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKT 1344
Query: 1371 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1430
SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH
Sbjct: 1345 SSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHH 1404
Query: 1431 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1486
SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
Sbjct: 1405 SPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1460
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapiens]
Length = 1584
Score = 2310 bits (5986), Expect = 0.0
Identities = 1247/1599 (77%), Positives = 1307/1599 (81%), Gaps = 128/1599 (8%)
Query: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTK 300
Query: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD
Sbjct: 301 FTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSD 360
Query: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ
Sbjct: 361 VPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQ 420
Query: 421 DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSS 480
DQAV + P H L+K + + ++ + L S S
Sbjct: 421 DQAVTSSAHHRGGHGVP-----HGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHR-PSQE 474
Query: 481 GSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGM--------------- 525
K +Q S + D + ++ L N E+ M
Sbjct: 475 MDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNR 534
Query: 526 ---------TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAK-VVTQRSEIGEKQ 575
++ +++ A ER+ T + E+ S +K V+Q + +
Sbjct: 535 PVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANH 594
Query: 576 DTELQEKETPTQVYQKDKQDADRPLSKMNR---AVNGETLKTGGDNKTLLHLGS------ 626
QE+ + PL N + +G T+++ G +L G
Sbjct: 595 TRHDQEERI---------MEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTL 645
Query: 627 -SAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKN--------------V 671
P +EKS +V Q ++Q+ + + TPT++ K+ V
Sbjct: 646 PQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAV 705
Query: 672 SGQT------------------DKCREETFKQES--------------------QPPEKN 693
+G+T K + ET K+ S P + +
Sbjct: 706 NGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLS 765
Query: 694 SGHSTSKGDRVAQSESKRR-------------KAEEILKSQT-------------PKGGD 727
S + + + D+ + K+ K + + +S++ PKGGD
Sbjct: 766 SKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD 825
Query: 728 KKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPD 787
KKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPD
Sbjct: 826 KKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPD 885
Query: 788 SSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVT 847
SSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVT
Sbjct: 886 SSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVT 945
Query: 848 GETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADG 907
GETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADG
Sbjct: 946 GETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADG 1005
Query: 908 RKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVH 967
RKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVH
Sbjct: 1006 RKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVH 1065
Query: 968 SKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVA 1027
SKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVA
Sbjct: 1066 SKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVA 1125
Query: 1028 SEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAII 1087
SEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAII
Sbjct: 1126 SEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAII 1185
Query: 1088 RSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF 1147
RSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF
Sbjct: 1186 RSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF 1245
Query: 1148 GSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARI 1207
GSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARI
Sbjct: 1246 GSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARI 1305
Query: 1208 SQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNF 1267
SQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNF
Sbjct: 1306 SQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNF 1365
Query: 1268 RKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFS 1327
RKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFS
Sbjct: 1366 RKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFS 1425
Query: 1328 KKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEK 1387
KKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEK
Sbjct: 1426 KKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEK 1485
Query: 1388 QLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALH 1447
QLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALH
Sbjct: 1486 QLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALH 1545
Query: 1448 PAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1486
PAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
Sbjct: 1546 PAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE 1584
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
Length = 1554
Score = 347 bits (891), Expect = 4e-95
Identities = 198/402 (49%), Positives = 254/402 (63%), Gaps = 29/402 (7%)
Query: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
MS TSWFLVSS G RHRLPRE+IFVGR++CELMLQSRSVDKQHAVINYD DEH VKDL
Sbjct: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
Query: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
GSLNGTFVND+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ
Sbjct: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
Query: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
+S K + S++ + + ++ E K + + +A R TPLYGQP
Sbjct: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQP 170
Query: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
SWWG+D+ + G+P + + G ++ A A + F REPSY
Sbjct: 171 SWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSY 225
Query: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRD 296
FEIPTKE QPSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+D
Sbjct: 226 FEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
Query: 297 HVTKFTSDQRH-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSK 355
H+TKF+ QR K+++PG M++ E KVADWL QN+P + +D
Sbjct: 286 HITKFSLRQRRPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRH 336
Query: 356 SIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
S KSD+PV+ + LKG+KH+DGTQSDSE+ A + LE
Sbjct: 337 STKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 378
Score = 307 bits (786), Expect = 6e-83
Identities = 316/1057 (29%), Positives = 496/1057 (46%), Gaps = 189/1057 (17%)
Query: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 580 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 636
Query: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 637 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 677
Query: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 678 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 728
Query: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 729 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 772
Query: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 773 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 831
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 832 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 878
Query: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 879 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 922
Query: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 923 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 978
Query: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 979 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 1038
Query: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 1039 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1097
Query: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 1098 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1150
Query: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1151 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1201
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
L + + A ++SR K + + G SR R Y ST++
Sbjct: 1202 --------LCCASRKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ 1249
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
T A ++R +S P + + +I TA EI
Sbjct: 1250 ----------------TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEI 1291
Query: 1205 ARISQ----DLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
AR+SQ D+A++A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+
Sbjct: 1292 ARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRI 1351
Query: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
+ SLNF+K+PP + S D + + + R +R+EV+ DNL+L
Sbjct: 1352 PEASLNFQKVPP---------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLML 1402
Query: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
+ V Q S+ IR++ + A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+
Sbjct: 1403 NPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILK 1462
Query: 1381 ELKRVEKQLQAINAMIDPDGTLEAL-NNMGFPSAMLP 1416
EL+RV+KQL+ INA++DP G+L+ L N S+ P
Sbjct: 1463 ELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQP 1499
>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
Length = 1484
Score = 307 bits (786), Expect = 6e-83
Identities = 316/1057 (29%), Positives = 496/1057 (46%), Gaps = 189/1057 (17%)
Query: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 510 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 566
Query: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 567 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 607
Query: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 608 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 658
Query: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 659 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 702
Query: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 703 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 761
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 762 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 808
Query: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 809 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 852
Query: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 853 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 908
Query: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 909 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 968
Query: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 969 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1027
Query: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 1028 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1080
Query: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1081 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1131
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
L + + A ++SR K + + G SR R Y ST++
Sbjct: 1132 --------LCCASRKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ 1179
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
T A ++R +S P + + +I TA EI
Sbjct: 1180 ----------------TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEI 1221
Query: 1205 ARISQ----DLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
AR+SQ D+A++A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+
Sbjct: 1222 ARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRI 1281
Query: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
+ SLNF+K+PP + S D + + + R +R+EV+ DNL+L
Sbjct: 1282 PEASLNFQKVPP---------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLML 1332
Query: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
+ V Q S+ IR++ + A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+
Sbjct: 1333 NPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILK 1392
Query: 1381 ELKRVEKQLQAINAMIDPDGTLEAL-NNMGFPSAMLP 1416
EL+RV+KQL+ INA++DP G+L+ L N S+ P
Sbjct: 1393 ELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQP 1429
Score = 225 bits (574), Expect = 2e-58
Identities = 138/332 (41%), Positives = 191/332 (57%), Gaps = 29/332 (8%)
Query: 71 VRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESEL 130
+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ+S K +
Sbjct: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
Query: 131 SKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDE 190
S++ + + ++ E K + + +A R TPLYGQPSWWG+D+
Sbjct: 61 SEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQPSWWGEDDGST 110
Query: 191 KRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQ 250
+ G+P + + G ++ A A + F REPSYFEIPTKE Q
Sbjct: 111 LPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSYFEIPTKETPQ 165
Query: 251 PSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRDHVTKFTSDQR 306
PSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+DH+TKF+ QR
Sbjct: 166 PSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQR 225
Query: 307 H-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYL 365
K+++PG M++ E KVADWL QN+P + +D S KSD+PV+
Sbjct: 226 RPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHT 276
Query: 366 KRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
+ LKG+KH+DGTQSDSE+ A + LE
Sbjct: 277 RTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 308
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 77.0 bits (188), Expect = 1e-13
Identities = 167/832 (20%), Positives = 295/832 (35%), Gaps = 73/832 (8%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ ++ + S T+S +S+ + TA
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITG---------SKTTTASTEGSEATTVSTTSSETTTAS 1137
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
+G+ + + F+ ++S + S SA GS + + T AST+
Sbjct: 1138 T---TGSEM--TTVFTTVSETTTVSTIGSEATTS--SAAGSEATTTSTEGSETTTASTAG 1190
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGS----AMPTSSSFKHRIKEQEDYIRDWTAH 1200
E + + T ++ +TT ++GS A T S + +
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
E + L A + S+T+SG TA STTVS+ A D
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 37.7 bits (86), Expect = 0.083
Identities = 103/568 (18%), Positives = 197/568 (34%), Gaps = 52/568 (9%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELI-PHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAK 809
+ + +++ T+ + T++S + + + S TT +E A A
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AG 1200
Query: 810 LREDNKTDEGPDTPSYNRDNS------------ISPESDVDTASTISLVTGETERKSTQK 857
+ G +T + + S +P S +T ++ ET ST
Sbjct: 1201 SETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1260
Query: 858 RK-SFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GS 903
+ + TSL +T S +T S ++ A + T +++TDV G+
Sbjct: 1261 LEPTATSLTGSETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGT 1316
Query: 904 RADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSAD 963
R G + SS P +D T + +VP ++ +S T + T
Sbjct: 1317 RTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVR 1373
Query: 964 EHVHSKLEGSKVTKSKTSPVVSGSSSKS 991
S E + T +T PV G+++ S
Sbjct: 1374 TTTGSTREPTSSTFQETGPVSMGTNTVS 1401
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 77.0 bits (188), Expect = 1e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1147 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1200
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSESTIAS-TASLEPT 1254
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1255 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 39.3 bits (90), Expect = 0.029
Identities = 101/557 (18%), Positives = 194/557 (34%), Gaps = 40/557 (7%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELIPHINKQTS--STPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEA 808
+ + +T+ ST S A TS++ E + + S T + +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 809 KLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRK-SFTSLYKD 867
+ + + +T + +P S +T ++ E+ ST + + TSL
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGS 1261
Query: 868 RCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GSRADGRKFVQSS 914
+T S +T S ++ A + T +++TDV G+R G + SS
Sbjct: 1262 ETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASS 1317
Query: 915 GRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSK 974
P +D T + +VP ++ +S T + T S E +
Sbjct: 1318 SVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374
Query: 975 VTKSKTSPVVSGSSSKS 991
T +T PV G+++ S
Sbjct: 1375 STFQETGPVSMGTNTVS 1391
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 77.0 bits (188), Expect = 1e-13
Identities = 167/832 (20%), Positives = 295/832 (35%), Gaps = 73/832 (8%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ ++ + S T+S +S+ + TA
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITG---------SKTTTASTEGSEATTVSTTSSETTTAS 1137
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
+G+ + + F+ ++S + S SA GS + + T AST+
Sbjct: 1138 T---TGSEM--TTVFTTVSETTTVSTIGSEATTS--SAAGSEATTTSTEGSETTTASTAG 1190
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGS----AMPTSSSFKHRIKEQEDYIRDWTAH 1200
E + + T ++ +TT ++GS A T S + +
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
E + L A + S+T+SG TA STTVS+ A D
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 37.7 bits (86), Expect = 0.083
Identities = 103/568 (18%), Positives = 197/568 (34%), Gaps = 52/568 (9%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELI-PHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAK 809
+ + +++ T+ + T++S + + + S TT +E A A
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AG 1200
Query: 810 LREDNKTDEGPDTPSYNRDNS------------ISPESDVDTASTISLVTGETERKSTQK 857
+ G +T + + S +P S +T ++ ET ST
Sbjct: 1201 SETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1260
Query: 858 RK-SFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GS 903
+ + TSL +T S +T S ++ A + T +++TDV G+
Sbjct: 1261 LEPTATSLTGSETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGT 1316
Query: 904 RADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSAD 963
R G + SS P +D T + +VP ++ +S T + T
Sbjct: 1317 RTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVR 1373
Query: 964 EHVHSKLEGSKVTKSKTSPVVSGSSSKS 991
S E + T +T PV G+++ S
Sbjct: 1374 TTTGSTREPTSSTFQETGPVSMGTNTVS 1401
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 77.0 bits (188), Expect = 1e-13
Identities = 167/832 (20%), Positives = 295/832 (35%), Gaps = 73/832 (8%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ ++ + S T+S +S+ + TA
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITG---------SKTTTASTEGSEATTVSTTSSETTTAS 1137
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
+G+ + + F+ ++S + S SA GS + + T AST+
Sbjct: 1138 T---TGSEM--TTVFTTVSETTTVSTIGSEATTS--SAAGSEATTTSTEGSETTTASTAG 1190
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGS----AMPTSSSFKHRIKEQEDYIRDWTAH 1200
E + + T ++ +TT ++GS A T S + +
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250
Query: 1201 REEIARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
E + L A + S+T+SG TA STTVS+ A D
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1302
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 37.7 bits (86), Expect = 0.083
Identities = 103/568 (18%), Positives = 197/568 (34%), Gaps = 52/568 (9%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELI-PHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAK 809
+ + +++ T+ + T++S + + + S TT +E A A
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AG 1200
Query: 810 LREDNKTDEGPDTPSYNRDNS------------ISPESDVDTASTISLVTGETERKSTQK 857
+ G +T + + S +P S +T ++ ET ST
Sbjct: 1201 SETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1260
Query: 858 RK-SFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GS 903
+ + TSL +T S +T S ++ A + T +++TDV G+
Sbjct: 1261 LEPTATSLTGSETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGT 1316
Query: 904 RADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSAD 963
R G + SS P +D T + +VP ++ +S T + T
Sbjct: 1317 RTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVR 1373
Query: 964 EHVHSKLEGSKVTKSKTSPVVSGSSSKS 991
S E + T +T PV G+++ S
Sbjct: 1374 TTTGSTREPTSSTFQETGPVSMGTNTVS 1401
>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 77.0 bits (188), Expect = 1e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1147 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1200
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSESTIAS-TASLEPT 1254
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1255 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 39.3 bits (90), Expect = 0.029
Identities = 101/557 (18%), Positives = 194/557 (34%), Gaps = 40/557 (7%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELIPHINKQTS--STPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEA 808
+ + +T+ ST S A TS++ E + + S T + +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 809 KLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRK-SFTSLYKD 867
+ + + +T + +P S +T ++ E+ ST + + TSL
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGS 1261
Query: 868 RCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GSRADGRKFVQSS 914
+T S +T S ++ A + T +++TDV G+R G + SS
Sbjct: 1262 ETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASS 1317
Query: 915 GRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSK 974
P +D T + +VP ++ +S T + T S E +
Sbjct: 1318 SVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374
Query: 975 VTKSKTSPVVSGSSSKS 991
T +T PV G+++ S
Sbjct: 1375 STFQETGPVSMGTNTVS 1391
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 76.6 bits (187), Expect = 2e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1147 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1200
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSETTIAS-TASLEPT 1254
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1255 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 40.8 bits (94), Expect = 0.010
Identities = 102/557 (18%), Positives = 194/557 (34%), Gaps = 40/557 (7%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELIPHINKQTS--STPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEA 808
+ + +T+ ST S A TS++ E + + S T + +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 809 KLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRK-SFTSLYKD 867
+ + + +T + +P S +T ++ ET ST + + TSL
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1261
Query: 868 RCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GSRADGRKFVQSS 914
+T S +T S ++ A + T +++TDV G+R G + SS
Sbjct: 1262 ETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASS 1317
Query: 915 GRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSK 974
P +D T + +VP ++ +S T + T S E +
Sbjct: 1318 SVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374
Query: 975 VTKSKTSPVVSGSSSKS 991
T +T PV G+++ S
Sbjct: 1375 STFQETGPVSMGTNTVS 1391
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 76.6 bits (187), Expect = 2e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 532 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 589
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 590 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 649
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 650 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 705
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 706 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 763
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 764 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 823
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 824 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 883
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 884 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 943
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 944 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 995
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 996 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1048
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1049 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1107
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1108 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1167
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1168 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1221
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1222 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSETTIAS-TASLEPT 1275
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1276 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1313
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 596 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 654
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 655 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 706
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 707 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 766
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 767 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 826
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 827 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 883
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 884 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 930
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 931 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 990
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 991 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1049
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1050 EGSETTTVTTAGSETTAVYTTGSE 1073
Score = 48.1 bits (113), Expect = 6e-05
Identities = 99/510 (19%), Positives = 176/510 (34%), Gaps = 45/510 (8%)
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+ + + T+AS S ++ S TT+ + TE M N T
Sbjct: 94 SENTTVSSAGSGTTTASMAGSES-TISTAGSETTTVSITGTETTMVSAMGSETTTNSTTS 152
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK-- 876
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 153 SETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG 212
Query: 877 DVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHS 936
T + S+ E T T S A S+ V + T S S
Sbjct: 213 SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 272
Query: 937 AISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTT 993
+ + D ET T T + + G + T + T+ P ++ + TT
Sbjct: 273 ETTAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 325
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDL 1051
+ T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 326 MASTIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 384
Query: 1052 LAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRL 1111
S + + SE T + + S T + S A V S + +
Sbjct: 385 ----------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSI 429
Query: 1112 SDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQ 1171
+DS+ + T GS F T AST E S T ++ +TT +
Sbjct: 430 TDSETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT 488
Query: 1172 SAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEI 1225
+AGS T+ + + + T + I D + E ++ E+
Sbjct: 489 TAGSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEM 544
Query: 1226 DSVTSSG---TAPSTTVSTAATTPGSAIDT 1252
+V++ G T STT S T + ++T
Sbjct: 545 TTVSTEGSENTTVSTTGSETTTVSTTGLET 574
Score = 40.8 bits (94), Expect = 0.010
Identities = 102/557 (18%), Positives = 194/557 (34%), Gaps = 40/557 (7%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 870 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 928
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 929 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 988
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 989 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1048
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1049 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1102
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1103 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1162
Query: 751 PIELIPHINKQTS--STPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEA 808
+ + +T+ ST S A TS++ E + + S T + +
Sbjct: 1163 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1222
Query: 809 KLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRK-SFTSLYKD 867
+ + + +T + +P S +T ++ ET ST + + TSL
Sbjct: 1223 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1282
Query: 868 RCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GSRADGRKFVQSS 914
+T S +T S ++ A + T +++TDV G+R G + SS
Sbjct: 1283 ETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASS 1338
Query: 915 GRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSK 974
P +D T + +VP ++ +S T + T S E +
Sbjct: 1339 SVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1395
Query: 975 VTKSKTSPVVSGSSSKS 991
T +T PV G+++ S
Sbjct: 1396 STFQETGPVSMGTNTVS 1412
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 76.6 bits (187), Expect = 2e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1147 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1200
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSETTIAS-TASLEPT 1254
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1255 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 76.6 bits (187), Expect = 2e-13
Identities = 173/828 (20%), Positives = 295/828 (35%), Gaps = 75/828 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP 629
E + ET T D++ + + T G + T+ GS
Sbjct: 629 TSSETTTASTEGSETTTV----STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 630 GKEK-------SETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
+ S T ET+ V T ++ T + S+ + T+ ET
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEG--SET 742
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQGS 740
++ E S +T A + S I+ S+T + + S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802
Query: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTE 800
T+ + I T ST S + +++ E + + + S TT + +E
Sbjct: 803 TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862
Query: 801 AVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTGE 849
A E+ T EG +T + + + S + + + + +T+S E
Sbjct: 863 TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922
Query: 850 TERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRK 909
T ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 923 TTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT 974
Query: 910 FVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTITS 1027
Query: 970 LEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKA 1024
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTV 1086
Query: 1025 SVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146
Query: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
S V + I + + + + + TS GS + + T AST+
Sbjct: 1147 FTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG 1200
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSETTIAS-TASLEPT 1254
Query: 1205 ARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1255 A-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/755 (19%), Positives = 265/755 (35%), Gaps = 63/755 (8%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAE-------AIIRSGARLVPSDKFSPRI 1103
+ + ++SA + SE T+S + + T + +G+ + I
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722
Query: 1104 RANSI------SRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHT 1157
SI + ++ + S GS + ++ T AST+ E T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782
Query: 1158 RLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE 1217
+ ++ +TT++ +A S M T + + E I TA E +S A
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTA--SETTTVS-----TAGS 830
Query: 1218 INDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDT 1252
A S T++ T+ + +T A+T GS T
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.1 bits (131), Expect = 5e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 76.3 bits (186), Expect = 2e-13
Identities = 174/829 (20%), Positives = 297/829 (35%), Gaps = 77/829 (9%)
Query: 453 SSAAAVMEERKPLTTSGFHHSEEGT-SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP 511
S AV +TT SE T S++GS+ L T + E M +
Sbjct: 511 SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE--MTTVST 568
Query: 512 LPLENETEISE-SGMTVRST-GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS 569
E T+ +E SG T ST GS T+ S + T +E S + ++ T +
Sbjct: 569 TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628
Query: 570 EIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGE------TLKTGGDNKTLLH 623
E + ET T V D + + R + T+ G T+
Sbjct: 629 TSSETTTASTEGSETTT-VSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687
Query: 624 LGSSAPGKE--KSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREE 681
GS SET K ++ +T + + A T ++ ++ + G E
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGS------E 741
Query: 682 TFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGD--KKESSKSLVRQG 739
T ++ E S +T A + S I+ S+T + + S
Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801
Query: 740 SFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDT 799
T+ + I T ST S + +++ E + + + S TT + +
Sbjct: 802 MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS 861
Query: 800 EAVMAFLEAKLREDNKT---------DEGPDTPSYNRDNSISPESDVDTA--STISLVTG 848
E A E+ T EG +T + + + S + + + + +T+S
Sbjct: 862 ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921
Query: 849 ETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGR 908
ET ST+ ++ T+ + ++T S++G+ S +T V +
Sbjct: 922 ETTTASTEGSETTTA--------STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET 973
Query: 909 KFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHS 968
++G + T+S+ S + + S+ ET T T+ E +
Sbjct: 974 TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET-------TTVSTTGTETTIT 1026
Query: 969 KLEGSKVTK-----SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADK 1023
EGS+ T S+T+ V + S +TT T T + AS ++L +
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTT 1085
Query: 1024 ASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTA 1083
S + +TT+ST+ T I+ + + + SE T + ++ S T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145
Query: 1084 EAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTS 1143
S V + I + + + + + TS GS + + T AST+
Sbjct: 1146 VFTTVSETTTVST------IGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA 1199
Query: 1144 EDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREE 1203
E + S T + +T+ SAGS T+++F I E I TA E
Sbjct: 1200 GSETTTASTSGSETNTACTTGSETSTPSSAGS--ETNTAF---IIGSETTIAS-TASLEP 1253
Query: 1204 IARISQDLALIAREINDVAGEIDSVTSSG-TAPSTTVSTAATTPGSAID 1251
A +L E V S+T+SG TA STTVS+ A D
Sbjct: 1254 TA-----TSLTGSETTTV-----SITASGATAASTTVSSTTFVLTKATD 1292
Score = 57.8 bits (138), Expect = 8e-08
Identities = 145/752 (19%), Positives = 266/752 (35%), Gaps = 57/752 (7%)
Query: 526 TVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETP 585
TV + GS T+ A + +E ++ + ++ +T + E ET
Sbjct: 146 TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205
Query: 586 T-QVYQKDKQDADRPLSKMNRA--VNGETLK--TGGDNKTLLHLGS--SAPGKEKSETDK 638
T + A S+ A + ET K T G T+ GS +A E SET+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNT 265
Query: 639 ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHST 698
+ +T + A T ++ + + G E T P ++
Sbjct: 266 AFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGS-----ETTMASTIGPETTKVSTAS 320
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
S+ V + S+ +A + T E++ + + GS T +
Sbjct: 321 SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGSETSTDSTTG--------- 370
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ T+++ T+AS + ++ S TT+ + D+E E T
Sbjct: 371 SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T + + I+ S D+ +T T TE T + S K +TGS +
Sbjct: 431 FETTTASTEGSEITIASTSDSETT----TASTEGSETTTVTTAGSETKTAYTTGS---ET 483
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T +S++G S +T + V ++G ++ T S S
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543
Query: 939 SDIMSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSK 990
+ + ++ ET + G T T+ E EGS T S+T+ V + S
Sbjct: 544 TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 603
Query: 991 STTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRID 1050
+T T ++ + AS + ++ SE +T S+T T
Sbjct: 604 TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 663
Query: 1051 LLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISR 1110
+ + ++SA + SE T+S + S T +I S V + I + S
Sbjct: 664 TITSTEGSETTTVSA-TGSETTVS-TEGSGTTTVSITGSETTKVSTTGSETTITSTEGSE 721
Query: 1111 LSDSKV----KSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALK 1166
++ + + + S GS + + T AST+ E + + T + + +
Sbjct: 722 ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSE 781
Query: 1167 TTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEID 1226
TT + GS S+ ++ +T + E I+ A ++ E
Sbjct: 782 TTMASTIGSETTKVSTASSKMTTV------FTENSE--TTIASTTASETTTVSTAGSETI 833
Query: 1227 SVTSSGTAPSTTVS------TAATTPGSAIDT 1252
+++G+ +TT S T A+T GS T
Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTT 865
Score = 55.8 bits (133), Expect = 3e-07
Identities = 98/504 (19%), Positives = 179/504 (35%), Gaps = 36/504 (7%)
Query: 762 TSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPD 821
T ST S T+AS + ++ S +TT D+E A T
Sbjct: 575 TDSTEGS-GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633
Query: 822 TPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKS 881
T + + + S D+ +T+ TG ++ TS +T S + T
Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTG--------SERTITSTEGSETTTVSATGSETTV 685
Query: 882 SSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDI 941
S+ G+ T S +T V + + G + + T+S S +
Sbjct: 686 STEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTA 745
Query: 942 MSSDQETYSCKPHG---RTPLTSADEHVHSKLEGSKVTK-----SKTSPVVSGSSSKSTT 993
+ ET S G T T++ E + + GS+ T S+T+ V + SS +T
Sbjct: 746 STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTV 805
Query: 994 LPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T + + S + ++ SE +TT+ST T + +
Sbjct: 806 FTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE--- 862
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
+ +A ++S T + ++ S T A S + S A+ ++
Sbjct: 863 --------TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-----TE 909
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
+ S GS + + T AST E + + T ++ +TT + +
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVA--GEIDSVTSS 1231
GS T+S+ + T E + + ++ E V+ G ++TS+
Sbjct: 970 GSETTTASTAGSETTTVSTAGSETTTASIEGSE-TTTVSSTGSETTTVSTTGTETTITST 1028
Query: 1232 GTAPSTTVSTAATTPGSAIDTREE 1255
+ +TTV+TA + + T E
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSE 1052
Score = 46.6 bits (109), Expect = 2e-04
Identities = 96/508 (18%), Positives = 175/508 (34%), Gaps = 44/508 (8%)
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
+ ++ S+ + T+ + + ++ S TT+ + TE M N T
Sbjct: 74 ENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSE 133
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSK--DV 878
T + + + S V + +T + ++ T+++ T +PS
Sbjct: 134 TTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
T + S+ E T T S A S+ V + T S S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTS---PVVSGSSSKSTTLP 995
+ + D ET T T + + G + T + T+ P ++ + TT+
Sbjct: 254 TAASTEDSET-------NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMA 306
Query: 996 RPRPTRTSLLRRARLGEASDSELADAD--KASVASEVSTTSSTSKPPTGRRNISRIDLLA 1053
T+ + A E + A ++ +AS +TT ST+ T +I +
Sbjct: 307 STIGPETTKVSTAS-SEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET-- 363
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSD 1113
S + + SE T + + S T + S A V S + ++D
Sbjct: 364 --------STDSTTGSETTTASTEGSETTTASTEGSEATTV-----STTGSETTTVSITD 410
Query: 1114 SKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSA 1173
S+ + T GS F T AST E S T ++ +TT + +A
Sbjct: 411 SETTT-TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA 469
Query: 1174 GSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIARE------INDVAGEIDS 1227
GS T+ + + + T + I D + E ++ E+ +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTT----VFTIGSDTTTASTEGSETTAVSATGSEMTT 525
Query: 1228 VTSSG---TAPSTTVSTAATTPGSAIDT 1252
V++ G T STT S T + ++T
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLET 553
Score = 40.8 bits (94), Expect = 0.010
Identities = 102/557 (18%), Positives = 194/557 (34%), Gaps = 40/557 (7%)
Query: 461 ERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
E TT+ SE T+S+ S + ++ + T E ++ E T
Sbjct: 849 EGSETTTASTEGSETTTASTESSETTTA-TTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 521 SESG--MTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTE 578
+E TV +TGS T+ AS T +E ++ + ++ +T +E E
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVT 967
Query: 579 LQEKETPT------QVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAP--G 630
ET T + ++ + + + TG + T+ G+
Sbjct: 968 TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS 1027
Query: 631 KEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPP 690
E SET T+ +T A + ++ ++ + +G ET +
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGS------ETTTASTADL 1081
Query: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNI 750
E + ++ G A + I S+T + + ++ S T +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 751 PIELIPHINKQTS--STPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEA 808
+ + +T+ ST S A TS++ E + + S T + +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 809 KLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRK-SFTSLYKD 867
+ + + +T + +P S +T ++ ET ST + + TSL
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1261
Query: 868 RCSTGSPSKDVTKSSSSGAREKMEKKT--KSRSTDV-----------GSRADGRKFVQSS 914
+T S +T S ++ A + T +++TDV G+R G + SS
Sbjct: 1262 ETTTVS----ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASS 1317
Query: 915 GRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSK 974
P +D T + +VP ++ +S T + T S E +
Sbjct: 1318 SVTMAPGMDFTASAASHTVPGIVLN---TSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374
Query: 975 VTKSKTSPVVSGSSSKS 991
T +T PV G+++ S
Sbjct: 1375 STFQETGPVSMGTNTVS 1391
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 66.6 bits (161), Expect = 2e-10
Identities = 131/697 (18%), Positives = 255/697 (36%), Gaps = 41/697 (5%)
Query: 567 QRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGS 626
Q+SE G K ++ + Y D D D + + + + D + S
Sbjct: 428 QKSEPGNKVGHSNTGSDSNSDGY--DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNS 485
Query: 627 SAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVS-GQTDKCREETFKQ 685
S+ G +D+ + +K + + + T S+ N + G D + ++ K
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKG 545
Query: 686 ESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK 745
+S + +S S++ D S+S + S + D +SS S S + +
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS-SDSDSSDSSDSDSSDSSNSSDS 604
Query: 746 PSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAF 805
+ + + S + SS + + +S +S+S D +SS +
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS------------- 651
Query: 806 LEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLY 865
DN S + D+S S +S ++S+ S + ++ S S +S
Sbjct: 652 -------DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 866 KDRC---------STGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGR 916
D S+ S S D S+SS + + S S+D + +D SS
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 917 I-RQPSVDLTD--DDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGS 973
S D +D D SS + + + SSD S + S+D S
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Query: 974 KVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASD-SELADADKASVASEVST 1032
+ S S S SS S + + + R+ +SD S+ +D+ +S +S+ S
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 1033 TSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGAR 1092
++ +S + + D + S + + S+++ S +S+ + + S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 1093 LVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRN 1152
SD + +NS + S S+ S S NS +D + +S+ SN +
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 1153 SPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLA 1212
+ + + + S+ S+ + SS + D + + S D
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD-- 1062
Query: 1213 LIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSA 1249
+ + +D + DS SS ++ S+ S ++ + S+
Sbjct: 1063 --SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Score = 64.3 bits (155), Expect = 8e-10
Identities = 119/583 (20%), Positives = 218/583 (37%), Gaps = 24/583 (4%)
Query: 668 SKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRV-AQSESKRRKAEEILKSQTPKGG 726
S + S +D K +S E +S S SK D + S ++ S +
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 727 DKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDP 786
D +SS S S S + + ++ + S+ SS + +S S S S D
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 787 DSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLV 846
DSS + D+ ++ D+ S + ++S S +S + S+ S
Sbjct: 727 DSSNSS-----DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 847 TGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRAD 906
+ ++ S S +S D S S S D + SS S + + S S+D + +D
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDS-SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 907 GRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHV 966
SS S + +D +S S+ S SSD S S+D
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS-NSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 967 HSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASV 1026
S + S + S S S SS S + + +S ++ S+ +D+ +S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS-------DSSNSSDSSDSSDSSN 952
Query: 1027 ASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAI 1086
+S+ S +S +S + S + + S S+ S + S SS SS ++++
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNS-----SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 1087 IRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDE 1146
S + + S +S S S S S+ S S +S +D + +S+
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 1147 FGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIAR 1206
S+ + + + + + S+ S+ + SS + D + +
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 1207 ISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSA 1249
S D + + +D + DS SS ++ S+ S ++ + S+
Sbjct: 1128 DSSD----SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Score = 57.0 bits (136), Expect = 1e-07
Identities = 118/658 (17%), Positives = 221/658 (33%), Gaps = 14/658 (2%)
Query: 472 HSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTG 531
+S+ SS+ S S +S +++ + + S N +E S+S S+
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS---DSSD 709
Query: 532 SATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQK 591
S +S +S + N S +S + + S+ D+ ++
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSNSSDSS 768
Query: 592 DKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQ 651
D D+ N + + ++ + + + SS +D S +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 652 QQEQREEAQWTPTKLSSKNVSGQTDKC--REETFKQESQPPEKNSGHSTSKGDRVAQSES 709
+ + + + + SS + G R ++ +S +S+ D +ES
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 710 KRRK-AEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSS 768
+ + S D SS S S + S + + + S+ SS
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948
Query: 769 LALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRD 828
+ S+ S DSS + D+ ++ D+ S + D
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 829 NSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGARE 888
+S S +S + S+ S + + S S +S D + S S SS + +
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 889 KMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQET 948
+ S S+D +D SS S D +D +S S+ S S+ ++
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 949 YSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRA 1008
+ +S E S + S S S SS S + + +S
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS----- 1181
Query: 1009 RLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSD 1068
++SDS + S S S+ SS S + + S + + S S+ S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Query: 1069 SEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSA 1126
+ S SS SS ++++ + SD S N+ SDS + S H ++
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 43.9 bits (102), Expect = 0.001
Identities = 79/470 (16%), Positives = 155/470 (32%), Gaps = 17/470 (3%)
Query: 473 SEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGS 532
S +G+ S S R S +S +++ + + S N ++ S+S + S S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 533 ATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKD 592
+S +S + + S S+ + + S+ + D+ + +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS-SNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 593 KQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSET-DKETSLVKQTLAKLQ 651
+D S + + N D+ S+ + S++ D S +
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 652 QQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKR 711
++ + S + S +D S + + +S + S
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 712 RKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLAL 771
++ S + D +SS S S + S N + +S + +S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 772 TSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSI 831
+ +S + S+S D S D++ ++ D+ S + D+S
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSS-------------DSSDSSDSSDSSNSSDSSDSSDSSD 1191
Query: 832 SPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKME 891
S +S + S+ S + ++ S S +S D + S S SS + +
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251
Query: 892 KKTKSRSTDVGSRADGRKFVQS-SGRIRQPSVDLTDDDQTSSVPHSAISD 940
S S+D S ++ QS SG D D + S HS D
Sbjct: 1252 SSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 65.1 bits (157), Expect = 5e-10
Identities = 189/978 (19%), Positives = 377/978 (38%), Gaps = 128/978 (13%)
Query: 354 SKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKV 413
+KSIK V+ K+ K H +G+ S S ++ + S+ EH R +HK+ KV
Sbjct: 178 TKSIKD---VFEKKRKKPTHSEGSDSSSNSSSSSESSSESEL--EHERSRRRKHKRRPKV 232
Query: 414 QATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHS 473
+ ++K + +A N+ P + + D + ++ S+A + KP+
Sbjct: 233 KRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSA---KREKPVV-----RP 284
Query: 474 EEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSA 533
EE ++ + + + + E +I + AP+ + + +S+SG ++ G+
Sbjct: 285 EEIPPVPENRFLLRRDMPVVTA----EPEPKIPDV-APIVSDQKPSVSKSGRKIKGRGT- 338
Query: 534 TSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDK 593
+ R R+ + +++ S K QR E K +
Sbjct: 339 --IRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSR 396
Query: 594 QDADRPLSKMNRA--VNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQ 651
D +R LS+ +R+ NG D T H G +++ + + KQ +
Sbjct: 397 WD-ERSLSQRSRSWSYNGYY----SDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRH 451
Query: 652 QQEQREE----AQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQS 707
+Q ++ + +K S++ + D RE + + S +S SK D+ QS
Sbjct: 452 KQTKKRRILIPSDIESSKSSTRRMKSSCD--RERSSRSSSLSSHHSSKRDWSKSDKDVQS 509
Query: 708 ESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPS 767
S + + +S++ + SS+S S + + K+ S +P
Sbjct: 510 -SLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPR 568
Query: 768 SLALTSASRIRERSESLDPDSSMDTTLILKDTEA----VMAFLEAKLREDNKTDEGPDTP 823
A + ++E L + + ++++ A V+ ++ K + P P
Sbjct: 569 KTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKP 628
Query: 824 SYNRDNSISPESD--VDTASTISLV----TGETE-----RKSTQKRKSFTSLYKDRCSTG 872
SY R + ++ + ST SL TG + K+++ +S S Y DR S
Sbjct: 629 SYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSES 688
Query: 873 SPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSS 932
SP +S S +R + ++ +RS + S + S R D + ++SS
Sbjct: 689 SP-----RSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSS 743
Query: 933 VPHSAISD--------IMSSDQETYSCKPHGRTPLTSADEHVHSK-LEG-------SKVT 976
+ D S + + S K H +S+++ +HSK ++G K +
Sbjct: 744 YTSISSDDGRRAKRRLRSSGKKNSVSHKKHS----SSSEKTLHSKYVKGRDRSSCVRKYS 799
Query: 977 KSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSST 1036
+S++S S S +S+ + T+++ + + + ++ S+
Sbjct: 800 ESRSSLDYSSDSEQSSV----QATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPH 855
Query: 1037 SKPPTGRRNIS-RIDLLAQPRRTRL--GSLSARSDSEATISRSSASSRTAEAIIRSGARL 1093
SK T + N+S + ++P+R + S+SE ++++S +
Sbjct: 856 SKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPS--------- 906
Query: 1094 VPSDKFSPRIRANSISRLSD--SKVKSMTSAHGSASV---NSRWR----RFPTDYASTSE 1144
SDK ++S S +S+ KVK T + + S+ N W+ R T + S
Sbjct: 907 --SDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSC 964
Query: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRI----------------K 1188
+NR P+ + + LK + + KH+ +
Sbjct: 965 SNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGE 1024
Query: 1189 EQEDYIRDWTAHRE-EIARISQDLALIAREI--------NDVAGEIDSVT-SSGTAPSTT 1238
E+E+ I D +E + ++S++ I I D++G+ D+VT SS T
Sbjct: 1025 EEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTK 1084
Query: 1239 VSTAATTPGSAIDTREEL 1256
+ + +A++T E +
Sbjct: 1085 DDSKLSISPTALNTEENV 1102
Score = 33.9 bits (76), Expect = 1.2
Identities = 123/619 (19%), Positives = 228/619 (36%), Gaps = 109/619 (17%)
Query: 385 GAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEKHK 444
G R R E +S + VQAT+ Q++ + Q N++ K
Sbjct: 788 GRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK-------EKQGQMERTHNKQEK 840
Query: 445 DLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLA------ANHTR 498
+ ++ + S +++ L + H G+ S+W S + +++
Sbjct: 841 NRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSK 900
Query: 499 HDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLAS--------QGERRRRTLPQL 550
+D + ++E+E+SE + V+ T +++ S + ++R +
Sbjct: 901 NDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDS 960
Query: 551 PNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVN-- 608
+ E++R K Q+ + G K++ + +E + K K+D K +A +
Sbjct: 961 EGSCSNSENNRGK--PQKHKHGSKENLK-REHTKKVKEKLKGKKDKKHKAPKRKQAFHWQ 1017
Query: 609 -----GETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQ--------------TLAK 649
GE + D+K + E +ET K+ L + T++
Sbjct: 1018 PPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSS 1077
Query: 650 LQQQEQREEAQWT--PTKLSSK-NVSG-------------------QTDKCREETFKQES 687
Q +++++ + PT L+++ NV+ QTD E S
Sbjct: 1078 DLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRS 1137
Query: 688 QPP--EKNSGHSTSKGDR------VAQSESKRRKAEEILKSQTPKG--------GDKKES 731
P E+ S ++ D + Q + E++K ++ G + S
Sbjct: 1138 SPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSS 1197
Query: 732 SKSLVRQGSFT-----IEKPSPNI------PIELIPHI---NKQTSSTPSSLALTSASRI 777
S SL G T EK N+ P++ + ++ N TSS LT+ +
Sbjct: 1198 SASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEM 1257
Query: 778 RERSESLDPDSSMDTTL-ILKDTEAVMAFLEAKLR-EDNKTDEGPDTPSYNRDN-SISPE 834
+ + ++ S L D A L + R +++ +DE TPS + D+ S SP
Sbjct: 1258 KPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDE--QTPSRDDDSQSRSPS 1315
Query: 835 SDVDTASTISL--VTGETERKSTQKRKSFTSLYKDRC-----STGSPSKDVTKSSSSGAR 887
+ T S + S + +S TS Y+ R S G S+ T+S SS R
Sbjct: 1316 RSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYR 1375
Query: 888 EKMEKKTKSRSTDVGSRAD 906
+T SRS S D
Sbjct: 1376 SYKSHRTSSRSRSRSSSYD 1394
Score = 32.7 bits (73), Expect = 2.7
Identities = 95/470 (20%), Positives = 185/470 (39%), Gaps = 71/470 (15%)
Query: 366 KRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEH-------KKLQKVQATEK 418
K+ +G+ S+SEN + K + +E+L+R H++ KK +K +A ++
Sbjct: 952 KQRTSTSDSEGSCSNSENNRGKPQKHKHGS-KENLKREHTKKVKEKLKGKKDKKHKAPKR 1010
Query: 419 ----HQDQAVVFGVDDNQDYNRPVINEKHK--------DLIKDWALSSAAAVMEERKPLT 466
H + FG ++ ++ + + ++ K + IKD L + + E+
Sbjct: 1011 KQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEED----- 1065
Query: 467 TSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERI--------MEFSAPLPLENET 518
SG H + T SS ++ + L+ + T + EE + +E S P +E+
Sbjct: 1066 LSGKH--DTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVL 1123
Query: 519 EISESGMTV----RSTGSATSLASQGERRRRTLPQLP---NEEKSLESHRAKVVTQRSEI 571
+ ++ M + RS+ + S R P + ++ + E +A+VV
Sbjct: 1124 Q-TDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVV------ 1176
Query: 572 GEKQDTELQEKETPTQVYQKDKQDAD-----RPLSKMNRAVNGETLKTGGDNKTLLHLGS 626
KQ++ + E + +V ++D A K A + K L +G+
Sbjct: 1177 --KQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGN 1234
Query: 627 SAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKC-------- 678
A + + E V T+ +++ Q R E + + K+ ++ + K
Sbjct: 1235 LAAPNAATSSAVEVK-VLTTVPEMKPQGLRIEIK-SKNKVRPGSLFDEVRKTARLNRRPR 1292
Query: 679 REETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
+E+ E P + S S ++SE+K R + + + SS S R
Sbjct: 1293 NQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR--SRSRSSTSSYRS 1350
Query: 739 GSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDS 788
S++ S + ++SS S + ++SR R RS S DP S
Sbjct: 1351 RSYS---RSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 64.3 bits (155), Expect = 8e-10
Identities = 154/764 (20%), Positives = 275/764 (35%), Gaps = 117/764 (15%)
Query: 575 QDTELQEKETPTQVYQKDKQDADR------PLSKMNRAVNGETLKTGGDNKTLLHLGSSA 628
+++ TP Q +K K+D R P + ++ + ++ ++K H +
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234
Query: 629 PGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQ 688
K KS+ K T A ++ R + + + + ++ + T +
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGR 294
Query: 689 PPEKNSGHSTSKGD----RVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIE 744
P SG +GD + ++R + E Q + K+ K ++ S T
Sbjct: 295 SPSPASGRR-GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK---KEKSATRP 350
Query: 745 KPSPNI------PIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKD 798
PSP P P + ++ +P LA T S+ E ++P S T
Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ-----EPVNPPSEASPTRDRSP 405
Query: 799 TEAVMAFLEAKLREDNKTDEGPDTPS---YNRDNSISPESDVDTASTISLVTGETERKST 855
++ KL + + ++ P +P +R S SPES + S E T
Sbjct: 406 PKS-----PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS--HREISSSPT 458
Query: 856 QKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSS- 914
K +S +D+ + +PS+ + +S S ++ ++++ + SR+ ++ +S
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
Query: 915 ----GRIRQPSV-DLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
GR R P + Q S + + + H R+P T
Sbjct: 519 AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR------ 572
Query: 970 LEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASE 1029
++S+T P G S T R +RT RR+R +
Sbjct: 573 ------SRSRT-PARRGRSRSRTPARRRSRSRTPTRRRSRS----------------RTP 609
Query: 1030 VSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRS 1089
S S+ P RR+ +R + + R S RS S R + SRT RS
Sbjct: 610 ARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS 669
Query: 1090 GARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDY--------AS 1141
+R P+ + S R R+ + +R S+ S T G + S RR + +
Sbjct: 670 RSR-TPARR-SGRSRSRTPARRGRSR--SRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
Query: 1142 TSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHR 1201
+S + +R S + +R +SP +K +R+ S S + SS + + K + R +
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR--SLSSPRSKAKSRLSLRRSLSGSS 783
Query: 1202 EEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVF 1261
+ SQ +R +G S T P + S+++
Sbjct: 784 PCPKQKSQTPPRRSR-----SGSSQPKAKSRTPPRRSRSSSSP----------------- 821
Query: 1262 DESLNFRKIPPLVHSKTPEGNNGRSGDPRP--QAAEPPDHLTIT 1303
PP SKTP + S P P ++ PP +IT
Sbjct: 822 ---------PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT 856
Score = 63.5 bits (153), Expect = 1e-09
Identities = 169/849 (19%), Positives = 299/849 (35%), Gaps = 147/849 (17%)
Query: 396 LEEHLRRHHSEHKKLQKVQATEKHQ--DQAVVFGVDDNQDYNRPVINEKHKDLIKDWALS 453
LEE + E +++Q+ AT + ++ V G + RP + E H+
Sbjct: 73 LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQ--------- 123
Query: 454 SAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFS--AP 511
A + E++ + F S+ S D + R E AP
Sbjct: 124 -LAELNEKKNERLRAAFGISDSYVDGSS-----------------FDPQRRAREAKQPAP 165
Query: 512 LPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEI 571
P + + + ES + T + +R RR+ P E+ S + K RSE
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK---HRSE- 221
Query: 572 GEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGK 631
+++ ++ +PT ++ +D R S+ T H +SA
Sbjct: 222 ---SESKKRKHRSPTPKSKRKSKDKKRKRSRST---------TPAPKSRRAHRSTSADSA 269
Query: 632 EKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPE 691
S+T + S + A+ T L+ ++ S + + + E P
Sbjct: 270 SSSDTSRSRS-------------RSAAAKTHTTALAGRSPSPASGR------RGEGDAPF 310
Query: 692 KNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIP 751
G ++++ ++ +K+ S + DK + KS R + P
Sbjct: 311 SEPGTTSTQRPSSPETATKQ-------PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363
Query: 752 IELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLR 811
P + ++ +P LA T S+ E ++P S T ++ KL
Sbjct: 364 PAPTPLLAERHGGSPQPLATTPLSQ-----EPVNPPSEASPTRDRSPPKS-----PEKLP 413
Query: 812 EDNKTDEGPDTP---SYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDR 868
+ + ++ P +P +R S SPES + S E T K +S +D+
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS--HREISSSPTSKNRSHGRAKRDK 471
Query: 869 CSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKF-----VQSSGRIRQPS-V 922
+ +PS+ + +S S ++ ++++ + SR+ ++ Q GR R P
Sbjct: 472 SHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRR 531
Query: 923 DLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADE---------HVHSKLEGS 973
+ Q S + + + H R+P T S+
Sbjct: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
Query: 974 KVTKSKT---------SPVVSGSSSKSTTLPRPRPTRTSLLRRA-------RLGEASDSE 1017
+ ++S+T +P G S T R TR+ + RR+ R G +
Sbjct: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
Query: 1018 LADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGS-LSARSDSEATISRS 1076
A ++ + S S+ P R SR A+ R+R + RS S + + R
Sbjct: 652 PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG 711
Query: 1077 SASSRTAEAIIRSGA---RLVPSDKFSPRIRANSI-----SRLSDSKVKSMTSAHGSASV 1128
+ SRT + RSG+ R S R R+NS SR+S + +S++S A
Sbjct: 712 RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771
Query: 1129 NSRWRRF---------------PTDYASTSEDEFGSNRNSPKHTRLRTSP----ALKTTR 1169
RR P S S +R P+ +R +SP KT
Sbjct: 772 RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831
Query: 1170 LQSAGSAMP 1178
QS S+ P
Sbjct: 832 RQSHSSSSP 840
Score = 63.5 bits (153), Expect = 1e-09
Identities = 190/921 (20%), Positives = 314/921 (34%), Gaps = 172/921 (18%)
Query: 415 ATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSE 474
++E D G+ NQ + PV++ + ++ + S+++ M++ P T S
Sbjct: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS------ 1436
Query: 475 EGTSSSGSKRWVSQWASLAANHTRHDQEERIMEF-SAPLPLENETEISESGMTVRSTGSA 533
S SGS + + + H+ + + P +E + S + T
Sbjct: 1437 -RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 534 TSLA-SQGERRRRTLPQLPNEEKSLESHRAKVVT-----QRSEIGEKQDTELQEKETPTQ 587
S + S E + L S S K V QRS G Q+ +++ +P +
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 588 VYQKD-----KQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSL 642
+ D K PL + +R+ + + D+K+ L S G DK +
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEV----DSKSRLSPRRSRSGSSPEVKDKPRAA 1611
Query: 643 VKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCR----EETFKQESQPPEKNSGHST 698
+ E + A P L ++ SG + K R E + ES P +
Sbjct: 1612 PRAQSGSDSSPEPKAPA---PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTA 1668
Query: 699 SKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHI 758
+G R E KS+TP SS L R+ +
Sbjct: 1669 RRG--------SRSSPEPKTKSRTPPRRRSSRSSPELTRKAR--------------LSRR 1706
Query: 759 NKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
++ SS+P + + T R S S E ++ R +
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVS--------------SPEPAEKSRSSRRRRSASSPR 1752
Query: 819 GPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDV 878
T R S P + R +++ K+ T+ +DR
Sbjct: 1753 TKTTSRRGRSPSPKPRG------------LQRSRSRSRREKTRTTRRRDR---------- 1790
Query: 879 TKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI 938
+ SS S +R + +++SR T R G S RQ S +TSS
Sbjct: 1791 SGSSQSTSRRRQRSRSRSRVT---RRRRGGSGYHSRSPARQES------SRTSSRRR--- 1838
Query: 939 SDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVV---SGSSSKSTTLP 995
+ RTP TS K ++S+TSP S S + T
Sbjct: 1839 -------------RGRSRTPPTS-----------RKRSRSRTSPAPWKRSRSRASPATHR 1874
Query: 996 RPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQP 1055
R R +RT L+ R R + S + P + RR+ SR + +
Sbjct: 1875 RSR-SRTPLISRRR-----------------------SRSRTSPVSRRRSRSRTSVTRRR 1910
Query: 1056 RRTRLGSLSARSDSEAT--ISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSIS-RLS 1112
R+R +S R T ++R + SRT RS +R P + R R ++ R S
Sbjct: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
Query: 1113 DSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSP---KHTRLRTSPALKTTR 1169
S+ +T + + RR S +R SP + +R RT PA++ R
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR-RR 2029
Query: 1170 LQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREI--NDVAGEIDS 1227
+S +P S R + R + AR + L I +G
Sbjct: 2030 SRSRTPLLPRKRS---RSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSD 2086
Query: 1228 VTSSGTAPSTTVSTAATTPGSAID-------TREELVDRVFDESLNFRKIPPLVHSKTPE 1280
+ S T P+T + + TP A++ +R + D + + PL S+TP
Sbjct: 2087 RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPM 2146
Query: 1281 GNNGRSGDPRPQAAEP--PDH 1299
++G P PDH
Sbjct: 2147 SVLQQAGGSMMDGPGPRIPDH 2167
Score = 52.4 bits (124), Expect = 3e-06
Identities = 165/840 (19%), Positives = 294/840 (35%), Gaps = 90/840 (10%)
Query: 353 DSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSK-----RATLEEHLRRHHSEH 407
+S S +S P K+ K K D G +S+S + R+ S R+ E R+H S
Sbjct: 176 ESSSSRSPTPKQKKKKK--KKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPT 233
Query: 408 KKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEK--HKDLIKDWALSSAA----AVMEE 461
K ++ +K + ++ +R + D + + S+AA +
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
Query: 462 RKPLTTSGFH------HSEEGTSSS---GSKRWVSQWASLAANHTRHDQEERIMEFSAPL 512
R P SG SE GT+S+ S ++ S D++E+ +P
Sbjct: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS 353
Query: 513 PLENETEISESGMTV----RSTGSATSLASQ-------------GERRRRTLPQLPNEEK 555
P + T T R GS LA+ R R+ P+ P +
Sbjct: 354 PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
Query: 556 SLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTG 615
S + + + + + E P ++ + P SK NR+ +G +
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK-NRS-HGRAKR-- 469
Query: 616 GDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQT 675
+K+ H S G+ +S + + + + QW ++ + +
Sbjct: 470 --DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR-----W 522
Query: 676 DKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSL 735
+ R + S+ P++ + R +S S RR +S +G + S++
Sbjct: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS-RSPATRG---RSRSRTP 578
Query: 736 VRQGSFTIEKPSPNIPIELIPHINKQTSSTPS----SLALTSASR-------IRERSESL 784
R+G P+ P + S TP+ S + T A R +R RS S
Sbjct: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSR 638
Query: 785 DPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTIS 844
P + + R P S R S +P + S
Sbjct: 639 SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS-GRSRSRTPARRGRSRSRTP 697
Query: 845 LVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSR 904
R ++ +S + + R +GS S+ KS +S R + + + + + SR
Sbjct: 698 RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
Query: 905 -----ADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPL 959
+ R +S +R+ + + S S SS + S P R+
Sbjct: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS 817
Query: 960 TSADEHVHSKLEGSKVTKSKTSP---VVSGSSSKSTTLPRPRPTRTSLL--RRARLGEAS 1014
+S+ S+ + S +SP V SG+ + ++ P+ S+ RR+ +
Sbjct: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
Query: 1015 DSELADADKA----SVASEVSTTSSTSKPPTGRRNIS---RIDLLAQPRRTRLGSLSARS 1067
D EL + S +S SST + R+ S ++ + PR+ S+ S
Sbjct: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
Query: 1068 DSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSAS 1127
S T + SR+ +RL+P ++S S D+KVK T S S
Sbjct: 938 PSRVTSRTTPRRSRSVSPCSNVESRLLPR-------YSHSGSSSPDTKVKPETPPRQSHS 990
Score = 38.5 bits (88), Expect = 0.049
Identities = 97/437 (22%), Positives = 158/437 (36%), Gaps = 95/437 (21%)
Query: 792 TTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETE 851
T L A + L N T +Y R + + +D A + + + ++
Sbjct: 2357 TAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQ 2416
Query: 852 RKSTQKRKSFTSLYKDRCSTGS---PSKDVTKSSSSGAREKMEKKTKSRSTDV-GSRADG 907
+ T +R S + + S P++D +S A + +++T V GS++
Sbjct: 2417 SRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS-- 2474
Query: 908 RKFVQSSGRIRQPSVDLTDDDQTSSVPHSAI--SDIMSSDQETYSCKPHGRTPLTSADEH 965
SSG + + D + SVP + SD+ T + +P L A E
Sbjct: 2475 ----LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
Query: 966 VHSKLEGSKVTKSKTSPVVSGSSSKS--------------------------TTLPR--- 996
S S + S +S S SSS S T P+
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 997 -----PRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDL 1051
P PT RR+ +S S +S S++SS+S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSS----------SSSSSSSSSSS-------------- 2626
Query: 1052 LAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRL 1111
S S+ S S ++ S SS+SS ++ + + G + +P SP+ + R
Sbjct: 2627 ----------SSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPK-KPPPGERR 2674
Query: 1112 SDSKVKSMTSAHGSASVNSR--WRRFPTDYAS-----TSEDEFGSNR------NSPKHTR 1158
S S K + S S S++ RR P+ S +S E GS R SP H R
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734
Query: 1159 LRTSPALKTTRLQSAGS 1175
R +P+ + R +S+ S
Sbjct: 2735 RRETPSPRPMRHRSSRS 2751
Score = 38.1 bits (87), Expect = 0.064
Identities = 73/393 (18%), Positives = 123/393 (31%), Gaps = 58/393 (14%)
Query: 584 TPTQVYQKDKQDADR---PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
TP + + ++R P S+M +A + L D S P + +D+
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPR-----SPVPS---AFSDQSR 2460
Query: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSK 700
L+ QT Q A T T + + + +PP S
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 701 GDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINK 760
A +K R++ S + SS S GS + + ++P++ + +
Sbjct: 2521 --LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Query: 761 QTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGP 820
S TP+ R E
Sbjct: 2579 VPSPTPAPKEAVREGRPPE----------------------------------------- 2597
Query: 821 DTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTK 880
TP+ + S S S ++S+ S + + S+ S +S S+ SP+K +
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
Query: 881 SSSSGAREKM----EKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHS 936
+ A K E++++S + S D R S R+PS + DQ SS
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER 2717
Query: 937 AISDIMSSDQETYSCKPHGRTPLTSADEHVHSK 969
D + S K TP H S+
Sbjct: 2718 GSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Score = 35.0 bits (79), Expect = 0.54
Identities = 86/397 (21%), Positives = 148/397 (37%), Gaps = 67/397 (16%)
Query: 623 HLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREET 682
H GSS+P + T + T ++++ E R +++ + SS + K + ET
Sbjct: 930 HSGSSSPSPSRV-TSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT-----KVKPET 983
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKG----GDK-----KESSK 733
PP ++ S S +V K+QTP G G K ++S
Sbjct: 984 ------PPRQSHSGSISPYPKV--------------KAQTPPGPSLSGSKSPCPQEKSKD 1023
Query: 734 SLVRQ--GSFTI-------EKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRE-RSES 783
SLV+ GS ++ P + + Q+ ++P + TS+ +R+ SES
Sbjct: 1024 SLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES 1083
Query: 784 LDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTI 843
S T+ + + E R + D G + S + +SPE + +
Sbjct: 1084 PSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSS 1143
Query: 844 SLVTGETE------RKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR 897
S T ++ R T + K +L +T SP + K S +++ E +
Sbjct: 1144 SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFK 1203
Query: 898 STDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT 957
T R R + SG P +Q S++P S S D+E
Sbjct: 1204 DT---LRTPPR---ERSGAGSSPETK----EQNSALPTS------SQDEELMEVVEKSEE 1247
Query: 958 PLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTL 994
P H+ S+L+ + ++SP V + S TL
Sbjct: 1248 PAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTL 1284
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 61.2 bits (147), Expect = 7e-09
Identities = 112/560 (20%), Positives = 200/560 (35%), Gaps = 84/560 (15%)
Query: 597 DRPLSKMNRAVNGETLKTGG--DNKTLLHLGSS---APGKEKSETDKETSLVKQTLAKLQ 651
D P K+ + + E L T +KT LG++ + +K T +S K+ K
Sbjct: 57 DGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKST 116
Query: 652 QQEQREEAQWTPTKLSSKNVSGQTDKCREETF----------------------KQESQP 689
++++R + ++P+ + K R +F KQ
Sbjct: 117 RKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSR 176
Query: 690 PEKNSGHSTSK-GDRVAQSESKRRKAEEILKSQTPKGGDK------KESSKSLVRQGSFT 742
P K+ H + R SES+ E + ++P+ G K + SK+L +
Sbjct: 177 PRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEA 236
Query: 743 IEKPSPNIPIELIPHINKQTSSTPSSLAL-----TSASRIRERSESLDPDSSMDTTLILK 797
P+ P++++ +++ + T S A T++ R S + DS DT+
Sbjct: 237 QSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPS 296
Query: 798 -DTEAVMAFLEAK------------LREDNKTDEGPDTPSYNRDN------SISPES--- 835
T + + + K L N +D G + + N ++SP S
Sbjct: 297 TQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGR 356
Query: 836 -------------DVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSS 882
+V +S + + K + S+ S S+ SP+ +
Sbjct: 357 ESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRY 416
Query: 883 SSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIM 942
+ EK++ SRS S++ R S R R+ P + D
Sbjct: 417 TQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQ 476
Query: 943 SSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPV--VSGSSSKSTTLPRPRPT 1000
++E + +P+ S LE ++T ++ P+ S S S +L
Sbjct: 477 QRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSW 536
Query: 1001 RTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRL 1060
+S R+ S S + + S++SS+ P G R+ SR R+R
Sbjct: 537 YSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSR-------SRSRS 589
Query: 1061 GSLSARSDSEATISRSSASS 1080
S S RS S + S S SS
Sbjct: 590 RSRS-RSQSRSYSSADSYSS 608
Score = 36.2 bits (82), Expect = 0.24
Identities = 111/526 (21%), Positives = 185/526 (35%), Gaps = 74/526 (14%)
Query: 846 VTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKM-----EKKTKSRSTD 900
+T + +K+K T + R S+ SPS K S + K +K+ S S+
Sbjct: 100 LTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP 159
Query: 901 VGSRADGRKFV-QSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPH--GRT 957
R D ++ QS R R+ H S SS+ SC+ GR+
Sbjct: 160 KSKRRDEKRHKKQSRSRPRKSH---------RHRHHRCPSRSQSSESRPSSCESRHRGRS 210
Query: 958 PLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPR-----PRPTRTSLLRRARLGE 1012
P SK T K SP S S L R T A L
Sbjct: 211 PEEGQKSRRRHSRRCSK-TLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
Query: 1013 ASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEAT 1072
+ S L + S E + + TS PP+ + + +R Q + + G LS + +
Sbjct: 270 KTASPLTTSRGRS--QEYDSGNDTSSPPSTQTSSARSR--GQEKGSPSGGLSKSRELNSG 325
Query: 1073 ISRSSASSRTAEAIIRSGARL------------------------------VPSDKFSPR 1102
+ S +S T + GA L VPS S
Sbjct: 326 NTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSP 385
Query: 1103 IRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRL--R 1160
++ S S S + +S+H S S N R T STS ++ +R SP ++ +
Sbjct: 386 MKGCS---RSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR-SPSYSSKSGK 441
Query: 1161 TSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREIND 1220
SP +++R + + S S S + K E + RE R + + + + D
Sbjct: 442 RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ--RERERARRRRRSYSPMRKRRRD 499
Query: 1221 VAGEIDS--VTSSGTAPSTTVSTAATTPGSAIDT-------REELVDRVFDESLNFRKIP 1271
+++ +TS+ P + ++ GS T R + S + +
Sbjct: 500 SPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSR 559
Query: 1272 PLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDN 1317
++T ++ RS P ++ + +R R+ SR D+
Sbjct: 560 RRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
>gi|212549782 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 60.1 bits (144), Expect = 2e-08
Identities = 165/796 (20%), Positives = 305/796 (38%), Gaps = 118/796 (14%)
Query: 369 KGNKHDDGTQSDSENAGAHRRCSKRATLEE-HLRRHHSEHKKLQKVQATEKHQDQAVVFG 427
K +K + SD + + K E H R KKL++ ++ ++ V
Sbjct: 301 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEV-- 358
Query: 428 VDDNQDYNRPVINEKHKDLIKD---WALSSAAAVMEERKPLT---TSGFHHSEEGTSSSG 481
+QD +++K K ++KD W S A++ + +T S +H EE
Sbjct: 359 --KSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWED 416
Query: 482 SKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENET---EISESGMTVRSTGSATSLAS 538
KR S +H+ D P L N I + T L +
Sbjct: 417 CKRDKS-----VNSHSFQDGR-------CPSSLSNSRTHKNIDSKEVDAMHQWENTPLKA 464
Query: 539 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR 598
+ R RT + E++S E +R +R Q T + K+T T + ++++ D+
Sbjct: 465 E---RHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDK 521
Query: 599 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQ---TLAKLQQQEQ 655
V + G DNK L S P + K++ D + S +K+ TL+ ++Q
Sbjct: 522 G------EVLDNGVSEGADNKELAMKAESGPNETKNK-DLKLSFMKKLNLTLSPAKKQPV 574
Query: 656 REEAQWTPTKL-SSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKA 714
++ Q T + S V + +T E G + + +++S +
Sbjct: 575 SQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEP 634
Query: 715 EEILKSQT-PKGG----DKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSL 769
+ L + T P+ G +K++ + LVR T+ P E +S PS +
Sbjct: 635 KVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTE---------TSFPSPM 685
Query: 770 ALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDN 829
+ +++ESL P + M T + + A + L+ D + G + + DN
Sbjct: 686 EI-------QQTESLFPSTGMKQT--INNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDN 736
Query: 830 S----ISP--ESDVDTASTISLVTGETERKSTQKRKSF-TSLYKDRCSTGSPSKDVT--- 879
S IS E V ++T+S T + S ++ L +D PS VT
Sbjct: 737 SDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLV 796
Query: 880 KSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAIS 939
+S S + K+T S D R ++G +T+SV H +
Sbjct: 797 ESKSCHLEPCLPKETLDSSLQQTELMDHR---MATG-------------ETNSVYHDDDN 840
Query: 940 DIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRP 999
++S D P +PL S V +KV ++++ P V ++ + P
Sbjct: 841 SVLSIDLNHLRPIPEAISPLNSPVRPV------AKVLRNESPPQVPVYNNSHKDVFLPNS 894
Query: 1000 TRTSLLRRARLGEASDSELADADKASVA-------------SEVSTTSSTSKPPTGRRNI 1046
++ ++ L + + + +DK + A E+ + S TSKP
Sbjct: 895 AHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKN 954
Query: 1047 SRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRAN 1106
S+ + A R+++ ++ R S T+ S +T I ++ ++K++ R +
Sbjct: 955 SKRRVSADVRKSK--TIPRRGKS--TVCLDKDSRKTHVRIHQT------NNKWNKRPDKS 1004
Query: 1107 SISRLSDSKVKSMTSA 1122
S S ++ K K M+++
Sbjct: 1005 SRSSKTEKKDKVMSTS 1020
>gi|6912288 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 60.1 bits (144), Expect = 2e-08
Identities = 165/796 (20%), Positives = 305/796 (38%), Gaps = 118/796 (14%)
Query: 369 KGNKHDDGTQSDSENAGAHRRCSKRATLEE-HLRRHHSEHKKLQKVQATEKHQDQAVVFG 427
K +K + SD + + K E H R KKL++ ++ ++ V
Sbjct: 301 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEV-- 358
Query: 428 VDDNQDYNRPVINEKHKDLIKD---WALSSAAAVMEERKPLT---TSGFHHSEEGTSSSG 481
+QD +++K K ++KD W S A++ + +T S +H EE
Sbjct: 359 --KSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWED 416
Query: 482 SKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENET---EISESGMTVRSTGSATSLAS 538
KR S +H+ D P L N I + T L +
Sbjct: 417 CKRDKS-----VNSHSFQDGR-------CPSSLSNSRTHKNIDSKEVDAMHQWENTPLKA 464
Query: 539 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR 598
+ R RT + E++S E +R +R Q T + K+T T + ++++ D+
Sbjct: 465 E---RHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDK 521
Query: 599 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQ---TLAKLQQQEQ 655
V + G DNK L S P + K++ D + S +K+ TL+ ++Q
Sbjct: 522 G------EVLDNGVSEGADNKELAMKAESGPNETKNK-DLKLSFMKKLNLTLSPAKKQPV 574
Query: 656 REEAQWTPTKL-SSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKA 714
++ Q T + S V + +T E G + + +++S +
Sbjct: 575 SQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEP 634
Query: 715 EEILKSQT-PKGG----DKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSL 769
+ L + T P+ G +K++ + LVR T+ P E +S PS +
Sbjct: 635 KVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTE---------TSFPSPM 685
Query: 770 ALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDN 829
+ +++ESL P + M T + + A + L+ D + G + + DN
Sbjct: 686 EI-------QQTESLFPSTGMKQT--INNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDN 736
Query: 830 S----ISP--ESDVDTASTISLVTGETERKSTQKRKSF-TSLYKDRCSTGSPSKDVT--- 879
S IS E V ++T+S T + S ++ L +D PS VT
Sbjct: 737 SDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLV 796
Query: 880 KSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAIS 939
+S S + K+T S D R ++G +T+SV H +
Sbjct: 797 ESKSCHLEPCLPKETLDSSLQQTELMDHR---MATG-------------ETNSVYHDDDN 840
Query: 940 DIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRP 999
++S D P +PL S V +KV ++++ P V ++ + P
Sbjct: 841 SVLSIDLNHLRPIPEAISPLNSPVRPV------AKVLRNESPPQVPVYNNSHKDVFLPNS 894
Query: 1000 TRTSLLRRARLGEASDSELADADKASVA-------------SEVSTTSSTSKPPTGRRNI 1046
++ ++ L + + + +DK + A E+ + S TSKP
Sbjct: 895 AHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKN 954
Query: 1047 SRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRAN 1106
S+ + A R+++ ++ R S T+ S +T I ++ ++K++ R +
Sbjct: 955 SKRRVSADVRKSK--TIPRRGKS--TVCLDKDSRKTHVRIHQT------NNKWNKRPDKS 1004
Query: 1107 SISRLSDSKVKSMTSA 1122
S S ++ K K M+++
Sbjct: 1005 SRSSKTEKKDKVMSTS 1020
>gi|212549532 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 60.1 bits (144), Expect = 2e-08
Identities = 165/796 (20%), Positives = 305/796 (38%), Gaps = 118/796 (14%)
Query: 369 KGNKHDDGTQSDSENAGAHRRCSKRATLEE-HLRRHHSEHKKLQKVQATEKHQDQAVVFG 427
K +K + SD + + K E H R KKL++ ++ ++ V
Sbjct: 301 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEV-- 358
Query: 428 VDDNQDYNRPVINEKHKDLIKD---WALSSAAAVMEERKPLT---TSGFHHSEEGTSSSG 481
+QD +++K K ++KD W S A++ + +T S +H EE
Sbjct: 359 --KSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWED 416
Query: 482 SKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENET---EISESGMTVRSTGSATSLAS 538
KR S +H+ D P L N I + T L +
Sbjct: 417 CKRDKS-----VNSHSFQDGR-------CPSSLSNSRTHKNIDSKEVDAMHQWENTPLKA 464
Query: 539 QGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADR 598
+ R RT + E++S E +R +R Q T + K+T T + ++++ D+
Sbjct: 465 E---RHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDK 521
Query: 599 PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQ---TLAKLQQQEQ 655
V + G DNK L S P + K++ D + S +K+ TL+ ++Q
Sbjct: 522 G------EVLDNGVSEGADNKELAMKAESGPNETKNK-DLKLSFMKKLNLTLSPAKKQPV 574
Query: 656 REEAQWTPTKL-SSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKA 714
++ Q T + S V + +T E G + + +++S +
Sbjct: 575 SQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEP 634
Query: 715 EEILKSQT-PKGG----DKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSL 769
+ L + T P+ G +K++ + LVR T+ P E +S PS +
Sbjct: 635 KVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTE---------TSFPSPM 685
Query: 770 ALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDN 829
+ +++ESL P + M T + + A + L+ D + G + + DN
Sbjct: 686 EI-------QQTESLFPSTGMKQT--INNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDN 736
Query: 830 S----ISP--ESDVDTASTISLVTGETERKSTQKRKSF-TSLYKDRCSTGSPSKDVT--- 879
S IS E V ++T+S T + S ++ L +D PS VT
Sbjct: 737 SDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLV 796
Query: 880 KSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAIS 939
+S S + K+T S D R ++G +T+SV H +
Sbjct: 797 ESKSCHLEPCLPKETLDSSLQQTELMDHR---MATG-------------ETNSVYHDDDN 840
Query: 940 DIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRP 999
++S D P +PL S V +KV ++++ P V ++ + P
Sbjct: 841 SVLSIDLNHLRPIPEAISPLNSPVRPV------AKVLRNESPPQVPVYNNSHKDVFLPNS 894
Query: 1000 TRTSLLRRARLGEASDSELADADKASVA-------------SEVSTTSSTSKPPTGRRNI 1046
++ ++ L + + + +DK + A E+ + S TSKP
Sbjct: 895 AHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKN 954
Query: 1047 SRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRAN 1106
S+ + A R+++ ++ R S T+ S +T I ++ ++K++ R +
Sbjct: 955 SKRRVSADVRKSK--TIPRRGKS--TVCLDKDSRKTHVRIHQT------NNKWNKRPDKS 1004
Query: 1107 SISRLSDSKVKSMTSA 1122
S S ++ K K M+++
Sbjct: 1005 SRSSKTEKKDKVMSTS 1020
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.8 bits (138), Expect = 8e-08
Identities = 76/394 (19%), Positives = 156/394 (39%), Gaps = 44/394 (11%)
Query: 348 ERTEEDSKSIKSDVPVYLKR---LKGNKHDDGTQSDSENAGAHRRCSK------RATLEE 398
E+ E + +K + P +R LK + ++ Q RR + LE+
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 399 HLRRHHSEHKKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIK--DWALSSAA 456
L+R H E ++ Q++ E+ Q+QA E+ K I W L S A
Sbjct: 671 RLKREHEEERREQEL--AEEEQEQA----------------RERIKSRIPKWQWQLESEA 712
Query: 457 AVMEER---KPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLP 513
+ + +P G +E + QW H + +EE+ +F+
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 514 LENETEISESGMTVRS--TGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEI 571
E ++E ++ R ER++R LP EE+ + R + ++
Sbjct: 773 AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 572 GEKQDTELQEKETPTQVYQKD---KQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSA 628
+++ +LQ +E Q+ +++ ++D +R S+ R + + K H +
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
Query: 629 PGKEKSETDKETSLVKQTLAKLQQQE------QREEAQWTPTKLSSKNVSGQTDKCREET 682
P ++ + KE L+++ +LQ++E Q +E Q+ + + + RE+
Sbjct: 893 PALQE-QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 683 FKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEE 716
+QE + + K +++ E ++R+ +E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Score = 42.0 bits (97), Expect = 0.004
Identities = 74/403 (18%), Positives = 151/403 (37%), Gaps = 28/403 (6%)
Query: 348 ERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEH 407
ER EE+ + + L+R + + + Q + RR + E+ LRR E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERRE--QQEERREQQERREQQEERREQQLRREQEER 346
Query: 408 KK--LQKVQATEKHQDQAVVFGVDDN--QDYNRPVINEKHKDLIKDWALSSAAAVMEERK 463
++ L++ Q E+ + Q ++ Q R + + L ++ L + E++
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 464 PLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAP-------LPLEN 516
++ +R + + +H+QE R L E
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEE----ERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 517 ETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQD 576
ETE E + + ERR R L E + + R + + + E +Q
Sbjct: 463 ETERHEQERRKQQL----KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 577 TELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSET 636
+ QE+E Q + +Q R + E L + K L K + E
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERR-----EQLLKREEEKRLEQERREQRLKREQE- 572
Query: 637 DKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSG-QTDKCREETFKQESQPPEKNSG 695
++ L+K+ + QQ+ +RE+ + +L + V + ++ RE+ K+E E+
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 696 HSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
S+ + + RR+ +E + + + +++ + L R+
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Score = 36.6 bits (83), Expect = 0.19
Identities = 40/198 (20%), Positives = 80/198 (40%), Gaps = 14/198 (7%)
Query: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
E RR QL +S + H + ++ ++ EL+ K +++KQ R
Sbjct: 184 EERRAEEEQL----QSCKGHETEEFPDEEQLRRRELLELRRKG------REEKQQQRR-- 231
Query: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
+ +R E K +T+L +E+ + +E ++ L KL++QE R E Q
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKS 720
+ Q + +EE ++ Q E+ + + + RR+ EE +
Sbjct: 292 EEEQQQQRLRREQQLRRKQEE--ERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 721 QTPKGGDKKESSKSLVRQ 738
Q + +++ + L R+
Sbjct: 350 QLRREQEEERREQQLRRE 367
Score = 32.7 bits (73), Expect = 2.7
Identities = 43/209 (20%), Positives = 83/209 (39%), Gaps = 32/209 (15%)
Query: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQ---DAD 597
+RRR+ L + EE+ L+ +++ + E +Q+ E Q +E QK KQ D D
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQE-KRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 598 R--------PLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAK 649
+ K N + + G +N+ L S +S+ D + L +Q
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ--- 1275
Query: 650 LQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSES 709
++ ++E +W + R+ F +E Q E+ + DR +Q E
Sbjct: 1276 -ERDREQERRRW---------------QQRDRHFPEEEQ-LEREEQKEAKRRDRKSQEEK 1318
Query: 710 KRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
+ + E K + + K + L+++
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQE 1347
Score = 31.2 bits (69), Expect = 7.8
Identities = 38/193 (19%), Positives = 85/193 (44%), Gaps = 10/193 (5%)
Query: 541 ERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPL 600
+RRR+ + EE+ L+ +++ + E +Q+ E Q ++ Q++++ R
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK--KDELQQEEEQLLREE 1037
Query: 601 SKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQ 660
+ R E + + + L G+E+ ET + L +Q + +++ Q+EE Q
Sbjct: 1038 REKRRLQERE--RQYREEEELQQEEEQLLGEER-ETRRRQELERQ--YRKEEELQQEEEQ 1092
Query: 661 WTPTKLSSKNVSGQTDKCREETFKQESQPP---EKNSGHSTSKGDRVAQSESKRRKAEEI 717
+ + + +CREE Q+ + E+ + +R + E + ++ EE
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 718 LKSQTPKGGDKKE 730
L + P+ ++E
Sbjct: 1153 LLREEPEKRRRQE 1165
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 57.8 bits (138), Expect = 8e-08
Identities = 236/1221 (19%), Positives = 435/1221 (35%), Gaps = 241/1221 (19%)
Query: 215 DAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHIT- 273
D ++V+++ A +EV ++P+++ ++ E T + D+ +T
Sbjct: 354 DTQKVKDEKQAKEKEV--------ESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTD 405
Query: 274 ---GAGHASFTIEFDDSTPGKVTIRDHVTK--FTSDQRHKSKKSSPGTQDLLGIQTGMMA 328
+ H S F++ T +V D + + TSD K+K++ TQ
Sbjct: 406 ITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTS--------- 456
Query: 329 PENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHR 388
+ +E +KS++ V+ L + D SD E R
Sbjct: 457 -------------------DSSEGKTKSVRHAY-VHKPYLYSKYYSD---SDDELTVEQR 493
Query: 389 RCSKRATLEEHL-----RRHHSEHKKLQKVQATEKHQDQAVVFGVDDNQDYNRPVINEKH 443
R S EE L R E K+ QK + T+ + + D ++ + + K
Sbjct: 494 RQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKA 553
Query: 444 ---KDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHD 500
K+++K+ V+E++ L+ S +S K+ + + + H
Sbjct: 554 ARIKEVLKE------RKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHC 607
Query: 501 QEERIME-------FSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNE 553
++E+I + P + +SES V + + L + +RR T +
Sbjct: 608 EKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGV 667
Query: 554 EKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLK 613
++ ++ K +RSEI TE +K+ T +K
Sbjct: 668 QEETDTRDVKRQVERSEI----CTEEPQKQKSTLKNEK---------------------- 701
Query: 614 TGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSG 673
HL K+ SET SL+K+ + +++ +RE+ + KLS K+
Sbjct: 702 ---------HL-----KKDDSETPHLKSLLKKEVKSSKEKPEREKTP-SEDKLSVKH--K 744
Query: 674 QTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSK 733
C +T ++ HS+ KG +V ++ K+ + ++ + K + +
Sbjct: 745 YKGDCMHKT-------GDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNER 797
Query: 734 SLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTT 793
L G KP I+ ++ K+ + L SA + + +S S D+
Sbjct: 798 KLSVLGK--DGKPVSEYIIKTDENVRKENNKKERRL---SAEKTKAEHKS---RRSSDSK 849
Query: 794 LILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDV--DTASTISLVTGETE 851
+ + + + R ++ +++ D S N D+++ PE V + T SL+ E
Sbjct: 850 IQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLL----E 905
Query: 852 RKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREK--------MEKKTKSRSTDVGS 903
K K KS T + + + TK +++ +K EK+ KS+ D
Sbjct: 906 EKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPF 965
Query: 904 RADGRKFV-------------QSSGRIRQPSVD---LTDDDQTSSVPHSAISDIMSSDQE 947
G + V SS R + P +D D TS+ +SD +
Sbjct: 966 EETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSD----GHK 1021
Query: 948 TYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRR 1007
+ S K H + DE+ +G +V S + S+ + + R RR
Sbjct: 1022 SRSLK-HSSKDIKKKDENKSDDKDGKEVDSSHEK-----ARGNSSLMEKKLSRRLCENRR 1075
Query: 1008 ARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARS 1067
L + E+A ++ A+ +ST S +S +R D+ P + +
Sbjct: 1076 GSLSQ----EMAKGEEKLAANTLSTPSGSSL----QRPKKSGDMTLIPEQEPM-----EI 1122
Query: 1068 DSEATISRSSASSRTAEAIIRSGARLVPSD----KFSPRIRANSI-SRLSDSKVKSMTSA 1122
DSE + S+T + + + + S+ K S ++ + + + +DSK +
Sbjct: 1123 DSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPAYK 1182
Query: 1123 HGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSS 1182
G + G N NS KH R S K +QSA S M
Sbjct: 1183 PGRGT--------------------GVNSNSEKHADHR-STLTKKMHIQSAVSKMNPGEK 1221
Query: 1183 FKHRIKEQEDYIRDWTAHR------EEIARISQDLALIAREINDVAGEIDSVTSSGTAPS 1236
E I T HR E R+ ++L A E + G+ S+ S
Sbjct: 1222 EPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLKNTAAEEHVAQGDATLEHSTNLDSS 1281
Query: 1237 TTVSTAATTP--------------------GSAIDTREELVDRVFDESLNFRKIPPLVHS 1276
++S+ P GS T + ++SL R+ L S
Sbjct: 1282 PSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHSALPNQSLTVRESEVLKTS 1341
Query: 1277 KTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKI------ 1330
+ EG G + D +A+ +T R + + D + K+
Sbjct: 1342 DSKEGGEGFTVDTPAKAS-----ITSKRHIPEAHQATLLDGKQGKVIMPLGSKLTGVIVE 1396
Query: 1331 RQSIDKTAGKIRILFKDKDRN 1351
++I K G + + K+ D N
Sbjct: 1397 NENITKEGGLVDMAKKENDLN 1417
Score = 56.6 bits (135), Expect = 2e-07
Identities = 134/609 (22%), Positives = 231/609 (37%), Gaps = 76/609 (12%)
Query: 474 EEGTSSSGSKRWVSQWASLAANHTRHDQ-EERIMEFSAPL-----------PLENETEIS 521
+ G SG R +SQ NHT Q E+ + EF A L P + + + S
Sbjct: 123 KSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEKPDTS 182
Query: 522 ESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQE 581
V + G + ++A+ T+ L N+E S + RA T ++ E+ +L
Sbjct: 183 LITQGVPTPGPSANVANDAMSILETITSL-NQEAS--AARASTETSNAKTSERASKKLPS 239
Query: 582 KETPTQVYQKDKQDADRPLSKMNRA-VNGETLKTGGDNKTLLHLGSSAPGKE-KSETDKE 639
+ T K++ D + + A GE L+T ++ L P +E K+ T +
Sbjct: 240 QPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDL--PCPVEEIKNYTKEH 297
Query: 640 TSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTS 699
+L+ L K QQE E+ + K K S + + E K++ + EK HS
Sbjct: 298 NNLI--LLNKDVQQESSEQKNKSTDKGEKKPDSNE----KGERKKEKKEKTEKKFDHSKK 351
Query: 700 KGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHIN 759
D + K+ K +E+ + P +K S+K+ T+E + + + ++
Sbjct: 352 SEDTQKVKDEKQAKEKEVESLKLP---SEKNSNKAK------TVEGTKEDFSL-IDSDVD 401
Query: 760 KQTSSTPSSLALTSASRIRE-RSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDE 818
T T SS+ + S E E + SM+ I D E + + NKT
Sbjct: 402 GLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDE--------EKNKQNKTKT 453
Query: 819 GPDTPSYNRDNSISPE------------SDVDTASTI----SLVTGETERKSTQKRKSFT 862
S + S+ SD D T+ + E E + +++ +
Sbjct: 454 QTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINRE 513
Query: 863 SLYKDRCSTGSPSK-DVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPS 921
L + R +K TK + + E TKS + +A K V ++ +
Sbjct: 514 KLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKS----LEPKAARIKEVLKERKVLEKK 569
Query: 922 VDLT----DDDQTSSVPHSAISDIMSSDQETYSCKPH-GRTPLTSADE--HVHSKLEGSK 974
V L+ D + +ET H + ++S+ E HVH+K E SK
Sbjct: 570 VALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSK 629
Query: 975 VTK--SKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVST 1032
+ S++ VV + ++S L R RTS G +++ D + SE+ T
Sbjct: 630 PARRLSESLHVVDENKNES-KLEREHKRRTS-TPVIMEGVQEETDTRDVKRQVERSEICT 687
Query: 1033 TSSTSKPPT 1041
+ T
Sbjct: 688 EEPQKQKST 696
Score = 34.3 bits (77), Expect = 0.92
Identities = 105/505 (20%), Positives = 187/505 (37%), Gaps = 96/505 (19%)
Query: 473 SEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRS--T 530
SE+ +S +K Q + +A +HT + AP E +T+++ +
Sbjct: 2559 SEDNLKTSTTKCITGQESKIAPSHTMIPPATYSVALLAPK--------CEQDLTIKNDYS 2610
Query: 531 GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQ 590
G T AS + + KS +VT SE + ++ +E+P V
Sbjct: 2611 GKWTDQASAEKTGDDN-----STRKSFPEEGDIMVTVSSE---ENVCDIGNEESPLNVLG 2662
Query: 591 KDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEK--SETDKETSLVKQTLA 648
K A+ KM V E K G + L S GK +E +E LV ++L
Sbjct: 2663 GLKLKANL---KMEAYVPSEEEKNG---EILAPPESLCGGKPSGIAELQREPLLVNESLN 2716
Query: 649 KLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSE 708
+ E + + + SG+ D E SGHS + + E
Sbjct: 2717 VENSGFRTNEEIHSESYNKGEISSGRKDNA------------EAISGHSVEADPKEVEEE 2764
Query: 709 S----KRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIP-----------IE 753
KR++ + L S+ D+ + + ++ T ++ P +E
Sbjct: 2765 ERHMPKRKRKQHYLSSE-----DEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLE 2819
Query: 754 LIPHINKQTSSTPSSLA-----LTSASRIRERSESLDPDS----SMDTTLILKDTEA--- 801
+P + +T+ST S + +S+ E+ E D D+ D +I+K
Sbjct: 2820 ELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPR 2879
Query: 802 -VMAFLEAKLREDNKTDEGPDTPSYNRDNSI-----SPESDVDTAS----TISLVTGETE 851
K+++D+KTD G T + +S + ES+ +TA+ +IS GE +
Sbjct: 2880 KYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEK 2939
Query: 852 ------RKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTD----- 900
R+ + ++S T D + P + KS S +K E+++ +
Sbjct: 2940 IVTSVRRRGRKPKRSLT--VSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDE 2997
Query: 901 ---VGSRADGRKFVQSSGRIRQPSV 922
+R+ R Q S PS+
Sbjct: 2998 PSGATTRSTTRSEAQRSKTQLSPSI 3022
>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
adaptor protein [Homo sapiens]
Length = 796
Score = 57.0 bits (136), Expect = 1e-07
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 13 GTRHRLPREMIFVGR-DDCELMLQSRSVDKQHAVINYDASTDE---------HLVKDLGS 62
GTR GR C++ L+ SV + HAV+ + AS + + DLGS
Sbjct: 179 GTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGS 238
Query: 63 LNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS 122
+GTF+N RIP +TY + + +RFG T LF ++QG PEE + E QL
Sbjct: 239 THGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLF-ILQG----PEEDREAESELTVTQLK 293
Query: 123 QKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEE 162
+ + ++ DS + + K + +E
Sbjct: 294 ELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDE 333
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 55.1 bits (131), Expect = 5e-07
Identities = 138/702 (19%), Positives = 258/702 (36%), Gaps = 102/702 (14%)
Query: 411 QKVQATEKHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGF 470
++ + E+ +D G D+ Q I ++ K+ ++ +M+ER P T S
Sbjct: 272 EEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDER-PKTRS-- 328
Query: 471 HHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRST 530
E+ G + SQ +H Q+E+ M+ ++PL E E EI S +
Sbjct: 329 --QEQEVLERGGRFTRSQ-EEARKSHLARQQQEKEMKTTSPLE-EEEREIKSSQGLKEKS 384
Query: 531 GSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRS-------EIGEKQDTELQEKE 583
S + +R++ +L LP + S E ++T+ + ++ +++ E E
Sbjct: 385 KSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGP 444
Query: 584 TPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDK--ETS 641
P + Q + D ++ V+ T++ G L L S + K +S +K E S
Sbjct: 445 APPVLIQLSPPNTDADTREL--LVSQHTVQLVGG---LSPLSSPSDTKAESPAEKVPEES 499
Query: 642 LV----KQTLAKLQQQEQRE-----EAQWTPTKLSSKNVS-GQTDKCREETFKQESQPPE 691
++ K TLA Q+ E AQ P K+ ++ G T++C ++ ++ +
Sbjct: 500 VLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKE--G 557
Query: 692 KNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIP 751
+ + H+ R+ QS S + + + S S + +
Sbjct: 558 RRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSG---SRSHSPLRSKQRDV 614
Query: 752 IELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLR 811
+ H N + S + TS SR R RS S S+ +L
Sbjct: 615 AQARTHANPRGRPKMGSRS-TSESRSRSRSRSRSASSNSRKSL----------------- 656
Query: 812 EDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCST 871
+P +RD+S S D +S + T + + K+R ST
Sbjct: 657 ----------SPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEP-------KERTST 699
Query: 872 GSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTS 931
S S + S + EK T+ + GS QP T + QTS
Sbjct: 700 SSSSVQARRLSQPESAEK--HVTQRLQPERGSPKKCEAEEAEPPAATQPQ---TSETQTS 754
Query: 932 SVP-----HSAISDIMSSDQETYSCKPHG---RTPLTSADEHVH-SKLEGSKVTKSKTSP 982
+P H + + +T +P P+ AD+ + + EGS
Sbjct: 755 HLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGS--------- 805
Query: 983 VVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTG 1042
V K ++LP+ + S++ + A +S+ ++T++T K P+
Sbjct: 806 -VEDEEKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPS- 863
Query: 1043 RRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
I + + ++ + + + EA + + SR +E
Sbjct: 864 ------ISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISE 899
Score = 43.9 bits (102), Expect = 0.001
Identities = 158/753 (20%), Positives = 265/753 (35%), Gaps = 145/753 (19%)
Query: 488 QWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTL 547
Q ++LA + D E + PLPL+ E G+T + +G R TL
Sbjct: 505 QKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTL 564
Query: 548 PQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQD--ADRPLSKMNR 605
L SHR K Q ++ + + + ++ D + PL R
Sbjct: 565 ---------LPSHRLK---QSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQR 612
Query: 606 AVNGETLKTGGDNKTLLHLGSSAPGKEKSET-DKETSLVKQTLAKLQQQEQREEA-QWTP 663
V +T + + +GS + + +S + + S + L R+ + +T
Sbjct: 613 DV--AQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTE 670
Query: 664 TKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTS-KGDRVAQSESKRRKAEEILKSQT 722
TK S SGQ Q +P E+ S S+S + R++Q ES + + L Q
Sbjct: 671 TKDPS---SGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRL--QP 725
Query: 723 PKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSE 782
+G KK ++ E P+ P QTS T +S L + RI E
Sbjct: 726 ERGSPKKCEAEE--------AEPPAATQP---------QTSETQTS-HLPESERIHHTVE 767
Query: 783 SLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTAST 842
+ + +MDT ++ R +N E P + N PE V+
Sbjct: 768 EKE-EVTMDT---------------SENRPENDVPEPPMPIADQVSNDDRPEGSVE---- 807
Query: 843 ISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVG 902
+ E+K + KSF K + S S +K V +S T+ G
Sbjct: 808 ------DEEKKESSLPKSF----KRKISVVSATKGVPAGNS--------------DTEGG 843
Query: 903 SRADGRKFVQSSGRI-RQPSVDLTDDDQTSSVP-------HSAISDIMS-----SDQETY 949
R++ S+ ++PS+ +T + S +P A+ D+ + S+ ET
Sbjct: 844 QPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETE 903
Query: 950 SCKPHGR-----------TPLTSADEHVHSKLEGSKVTKS-KTSPVVSGSSSKSTTLPRP 997
G T + A+ + + E + K + P V S LP P
Sbjct: 904 RNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPP 963
Query: 998 RPTRTSLLRRARLGEASDSELADADKASVASEVS---TTSSTSKPPTGR-RNISRIDLLA 1053
+++ LG+ K+ V+ + T+ PP G+ NI I L
Sbjct: 964 AEHE---VKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLV 1020
Query: 1054 QPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLS- 1112
+P LG L E + R+G LV + +I+++ S
Sbjct: 1021 RP--FTLGQLK-------------------ELLGRTGT-LVEEAFWIDKIKSHCFVTYST 1058
Query: 1113 -DSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF--GSNRNSPKHTRLRTSPALKTTR 1169
+ V + T+ HG S + DYA E ++ G + P T+ +
Sbjct: 1059 VEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGIPRPLH 1118
Query: 1170 LQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHRE 1202
P + +EQE +R+ A RE
Sbjct: 1119 PPPPPPVQPPQHP-RAEQREQERAVREQWAERE 1150
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.1 bits (131), Expect = 5e-07
Identities = 153/731 (20%), Positives = 261/731 (35%), Gaps = 107/731 (14%)
Query: 509 SAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQR 568
++P+P+ E+ ++ + + L + E+ +T + EK E+ + +
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQ-----VKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPM 1188
Query: 569 SEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLK--------TGGDNKT 620
+KQ+ EK+ + + +K ++ L + E K T D K
Sbjct: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
Query: 621 LLHLGSSAPGKEKSETDK------ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQ 674
L +SAP ++K + K E L + K Q+ ++ + + + +
Sbjct: 1249 LPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPK 1308
Query: 675 TDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKS 734
D +T K++ QPP T+K D+V + K K ++ KS T + +S +
Sbjct: 1309 EDDKTTKTIKEQPQPP------CTAKPDQVEPGKEKTEKEDD--KSDT-SSSQQPKSPQG 1359
Query: 735 LVRQG--SFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDT 792
L G S I IP LIP T L S +E S S D +
Sbjct: 1360 LSDTGYSSDGISSSLGEIP-SLIP-----TDEKDILKGLKKDSFSQESSPSSPSDLAKLE 1413
Query: 793 TLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRD----NSISPESDVDTASTISLVTG 848
+ +L EA + L A + + KT +P +D S+S ++ T S +
Sbjct: 1414 STVLSILEAQASTL-ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEI-TISEEEIKES 1471
Query: 849 ETERKSTQKR------------KSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKS 896
+ ERK T K+ K + D + P V +SS S E +
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES---ENSPVPQRK 1528
Query: 897 RSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGR 956
R T VGS + + S Q S + D + + SA D S+ + +
Sbjct: 1529 RRTSVGSSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEF------- 1577
Query: 957 TPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSL---LRRARLGEA 1013
+ + + + S E K ++K ++ + T R + TS+ R
Sbjct: 1578 --IRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT----RKSSTSIDEDAGRRHSWHD 1631
Query: 1014 SDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATI 1073
D E D E + S TG + R + + T SA S + T
Sbjct: 1632 EDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI-ELNSTIADKYSAESSQKKT- 1689
Query: 1074 SRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWR 1133
S E + S +D R R S L S TS
Sbjct: 1690 --SLYFDEEPELEMES-----LTDSPEDRSRGEGSSSLHASSFTPGTS------------ 1730
Query: 1134 RFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPT--SSSFKHRIKEQE 1191
PT +S ED + +SP H + S + R + G +PT SS + ++E+E
Sbjct: 1731 --PTSVSSLDED----SDSSPSHKK-GESKQQRKARHRPHGPLLPTIEDSSEEEELREEE 1783
Query: 1192 DYIRDWTAHRE 1202
+ +++ RE
Sbjct: 1784 ELLKEQEKQRE 1794
Score = 36.6 bits (83), Expect = 0.19
Identities = 149/748 (19%), Positives = 258/748 (34%), Gaps = 155/748 (20%)
Query: 73 IPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSK 132
+P Q + K E +++ + + V+ E L EK + QK ES+L K
Sbjct: 1150 VPPQVKLVKKQEQEVKTEAEKVILEKVK-------ETLSMEKIPPMVTTDQKQEESKLEK 1202
Query: 133 SASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKR 192
A ++ K + E ++SEEK PL + +D+
Sbjct: 1203 D-KASALQEKKPLPEEKKLIPEEEKIRSEEKK----------PLLEEKKPTPEDKKLLPE 1251
Query: 193 AFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPS 252
A KT+ PEE+ H+ S I +++E + A + ++P TK PS
Sbjct: 1252 A-KTSA-PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQE----GKQPQ-----TKMEGLPS 1300
Query: 253 QITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIR--DHVTKFTSDQRHKSK 310
+S E D + I T + D PGK D + +S Q+ KS
Sbjct: 1301 GTPQSLPKE---DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 311 K-------SSPGTQDLLGIQTGMMAPENK------VADWLAQNNPPQMLWERTEEDSKSI 357
+ SS G LG ++ + K D +Q + P + + +S ++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES-TV 1416
Query: 358 KSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATE 417
S + L K + TQ + + K +L E L SE + E
Sbjct: 1417 LSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEE------EIKE 1470
Query: 418 KHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWAL------------SSAAAVMEERKPL 465
+++ F D QD +++ + + D S + + +RK
Sbjct: 1471 SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Query: 466 TTSGFHHSEE--GTSSSGS--------KRWVSQWASLAANHTRHDQ--EERIMEFSAPLP 513
T+ G S+E S GS K+ + A A+ + D+ ++ E S+
Sbjct: 1531 TSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTE 1590
Query: 514 LENETEISESGMTVR------STGSATSLASQGERRRR----------TLPQLP-NEEKS 556
+ + E G + S+TS+ RR P+L E KS
Sbjct: 1591 SQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKS 1650
Query: 557 LESH-----------RAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNR 605
ES R K + S I +K E +K+T ++ P +M
Sbjct: 1651 QESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE-------PELEMES 1703
Query: 606 AVNGETLKTGGDNKTLLHLGSSAPG------------KEKSETDKETSLVKQTLAK---- 649
+ ++ G+ + LH S PG + S + K+ +Q A+
Sbjct: 1704 LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPH 1763
Query: 650 ----------------------LQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQES 687
L++QE++ E + K SSK D+ R + ++
Sbjct: 1764 GPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 688 QPPEKNSGHSTSKGDRVAQSESKRRKAE 715
+ P N S + + +E R+ AE
Sbjct: 1824 KTPPSN----LSPIEDASPTEELRQAAE 1847
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.1 bits (131), Expect = 5e-07
Identities = 153/731 (20%), Positives = 261/731 (35%), Gaps = 107/731 (14%)
Query: 509 SAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQR 568
++P+P+ E+ ++ + + L + E+ +T + EK E+ + +
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQ-----VKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPM 1188
Query: 569 SEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLK--------TGGDNKT 620
+KQ+ EK+ + + +K ++ L + E K T D K
Sbjct: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
Query: 621 LLHLGSSAPGKEKSETDK------ETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQ 674
L +SAP ++K + K E L + K Q+ ++ + + + +
Sbjct: 1249 LPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPK 1308
Query: 675 TDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKS 734
D +T K++ QPP T+K D+V + K K ++ KS T + +S +
Sbjct: 1309 EDDKTTKTIKEQPQPP------CTAKPDQVEPGKEKTEKEDD--KSDT-SSSQQPKSPQG 1359
Query: 735 LVRQG--SFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDT 792
L G S I IP LIP T L S +E S S D +
Sbjct: 1360 LSDTGYSSDGISSSLGEIP-SLIP-----TDEKDILKGLKKDSFSQESSPSSPSDLAKLE 1413
Query: 793 TLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRD----NSISPESDVDTASTISLVTG 848
+ +L EA + L A + + KT +P +D S+S ++ T S +
Sbjct: 1414 STVLSILEAQASTL-ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEI-TISEEEIKES 1471
Query: 849 ETERKSTQKR------------KSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKS 896
+ ERK T K+ K + D + P V +SS S E +
Sbjct: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES---ENSPVPQRK 1528
Query: 897 RSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGR 956
R T VGS + + S Q S + D + + SA D S+ + +
Sbjct: 1529 RRTSVGSSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEF------- 1577
Query: 957 TPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSL---LRRARLGEA 1013
+ + + + S E K ++K ++ + T R + TS+ R
Sbjct: 1578 --IRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT----RKSSTSIDEDAGRRHSWHD 1631
Query: 1014 SDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATI 1073
D E D E + S TG + R + + T SA S + T
Sbjct: 1632 EDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTI-ELNSTIADKYSAESSQKKT- 1689
Query: 1074 SRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWR 1133
S E + S +D R R S L S TS
Sbjct: 1690 --SLYFDEEPELEMES-----LTDSPEDRSRGEGSSSLHASSFTPGTS------------ 1730
Query: 1134 RFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPT--SSSFKHRIKEQE 1191
PT +S ED + +SP H + S + R + G +PT SS + ++E+E
Sbjct: 1731 --PTSVSSLDED----SDSSPSHKK-GESKQQRKARHRPHGPLLPTIEDSSEEEELREEE 1783
Query: 1192 DYIRDWTAHRE 1202
+ +++ RE
Sbjct: 1784 ELLKEQEKQRE 1794
Score = 36.6 bits (83), Expect = 0.19
Identities = 149/748 (19%), Positives = 258/748 (34%), Gaps = 155/748 (20%)
Query: 73 IPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSK 132
+P Q + K E +++ + + V+ E L EK + QK ES+L K
Sbjct: 1150 VPPQVKLVKKQEQEVKTEAEKVILEKVK-------ETLSMEKIPPMVTTDQKQEESKLEK 1202
Query: 133 SASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKR 192
A ++ K + E ++SEEK PL + +D+
Sbjct: 1203 D-KASALQEKKPLPEEKKLIPEEEKIRSEEKK----------PLLEEKKPTPEDKKLLPE 1251
Query: 193 AFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPS 252
A KT+ PEE+ H+ S I +++E + A + ++P TK PS
Sbjct: 1252 A-KTSA-PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQE----GKQPQ-----TKMEGLPS 1300
Query: 253 QITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIR--DHVTKFTSDQRHKSK 310
+S E D + I T + D PGK D + +S Q+ KS
Sbjct: 1301 GTPQSLPKE---DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 311 K-------SSPGTQDLLGIQTGMMAPENK------VADWLAQNNPPQMLWERTEEDSKSI 357
+ SS G LG ++ + K D +Q + P + + +S ++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES-TV 1416
Query: 358 KSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATE 417
S + L K + TQ + + K +L E L SE + E
Sbjct: 1417 LSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEE------EIKE 1470
Query: 418 KHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWAL------------SSAAAVMEERKPL 465
+++ F D QD +++ + + D S + + +RK
Sbjct: 1471 SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Query: 466 TTSGFHHSEE--GTSSSGS--------KRWVSQWASLAANHTRHDQ--EERIMEFSAPLP 513
T+ G S+E S GS K+ + A A+ + D+ ++ E S+
Sbjct: 1531 TSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTE 1590
Query: 514 LENETEISESGMTVR------STGSATSLASQGERRRR----------TLPQLP-NEEKS 556
+ + E G + S+TS+ RR P+L E KS
Sbjct: 1591 SQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKS 1650
Query: 557 LESH-----------RAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNR 605
ES R K + S I +K E +K+T ++ P +M
Sbjct: 1651 QESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE-------PELEMES 1703
Query: 606 AVNGETLKTGGDNKTLLHLGSSAPG------------KEKSETDKETSLVKQTLAK---- 649
+ ++ G+ + LH S PG + S + K+ +Q A+
Sbjct: 1704 LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPH 1763
Query: 650 ----------------------LQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQES 687
L++QE++ E + K SSK D+ R + ++
Sbjct: 1764 GPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 688 QPPEKNSGHSTSKGDRVAQSESKRRKAE 715
+ P N S + + +E R+ AE
Sbjct: 1824 KTPPSN----LSPIEDASPTEELRQAAE 1847
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 54.7 bits (130), Expect = 7e-07
Identities = 102/602 (16%), Positives = 231/602 (38%), Gaps = 50/602 (8%)
Query: 494 ANHTRHDQEERI--MEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLP 551
+ H + EE+I +E S + E + E+ +T T A + E +
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK-------- 484
Query: 552 NEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGET 611
EE+ E A+ + ++ ++ EKE + V ++ K A+ + A +
Sbjct: 485 -EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 612 LKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNV 671
+K+ K +P KE++++ E ++ AK + + E +P K +K+
Sbjct: 544 VKSPEKAK--------SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 672 SGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESK---RRKAEEILKSQTPKGGDK 728
+ E ++++ P K S ++ + E+K K+ E KS T +
Sbjct: 596 A-------EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 729 KESSKSLVRQGSFTIEKPSPNIPIEL-IPHINKQTSSTPSSLALTSASRIRERSESLDPD 787
E +KS ++ + + EK + E P K + + S ++E ++S +
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708
Query: 788 SSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVT 847
S +K+ ++ ++E+ KT E +P S + A T+ + +
Sbjct: 709 KSP-----VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763
Query: 848 GETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADG 907
E + + ++ +S + ++ SP K+ KS A+ +++ K+ ++ + +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAK--SPVKEEVKSPEK-AKSPLKEDAKAPEKEIPKKEEV 820
Query: 908 RKFVQSSGRIRQPSV----DLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSAD 963
+ V+ + ++ V ++++ + P + ++ P P +
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE-----APKKEAPKPKVE 875
Query: 964 EHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADK 1023
E +E K +K + + K T + P + + A+ E ++ + D
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Query: 1024 ASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTA 1083
A A E S + K + ++ + +P A+ D + T+S+ + +
Sbjct: 936 AK-AKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED-DKTLSKEPSKPKAE 992
Query: 1084 EA 1085
+A
Sbjct: 993 KA 994
Score = 48.1 bits (113), Expect = 6e-05
Identities = 128/656 (19%), Positives = 233/656 (35%), Gaps = 90/656 (13%)
Query: 72 RIPE-QTYITLKLEDKLRFGYDTNLFTVVQGEM----RVPEEALKHE-KFTIQLQLSQKS 125
+IP T+I +K E+K++ + TV+ E +V EE + E K + + ++
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 126 SESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGD 185
E + S A+ A + + +K E K+ + P
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 186 DEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPF-CREPSYFEIP 244
++ + PE K+ E + + K E+ + A EE P + P + P
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 245 TKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSD 304
KE + +S + E + + + A + + +P K + +
Sbjct: 608 VKEEAKSPAEAKSPVKE---EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK-----EE 659
Query: 305 QRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSI-KSDVPV 363
+ K SP ++ +PE + A+ P+ +E++KS K+ PV
Sbjct: 660 AKSPEKAKSP-------VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 364 YLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQ------KVQATE 417
+ K + +++ + K + + K L K A E
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 418 KHQDQAVVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGT 477
+ + A F EK K +K+ S A + PL +E
Sbjct: 773 EARSPADKFP-------------EKAKSPVKEEVKSPEKA----KSPLKEDAKAPEKEIP 815
Query: 478 SSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLA 537
K V + EE+ E P + E ++ T ++ S
Sbjct: 816 KKEEVKSPVKE-------------EEKPQEVKVKEP-PKKAEEEKAPATPKTEEKKDSKK 861
Query: 538 SQGERRRRTLPQL-----PNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKD 592
+ ++ P++ P EK ES KV ++ E +K+ EKE P +V +
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKES---KVEAKKEEAEDKKKVPTPEKEAPAKV--EV 916
Query: 593 KQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQ 652
K+DA +P K E K D+ A KE + K+T K+ AK +
Sbjct: 917 KEDA-KPKEKT------EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT---KEEKAKKPE 966
Query: 653 QEQREEAQWTPTKLSSKNVSGQTDKCREE-------TFKQESQPPEKNSGHSTSKG 701
++ + EA+ K K +S + K + E T +++S+PPEK + +KG
Sbjct: 967 EKPKTEAK---AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 54.7 bits (130), Expect = 7e-07
Identities = 203/1004 (20%), Positives = 370/1004 (36%), Gaps = 149/1004 (14%)
Query: 246 KEFQQPSQITESTIHEIP-TKDTPSSHITGAGHASFTIEFDDSTPGKVTIRD-HVTKFTS 303
+E P + I P T+ ++ G H S I + P K++ RD H K +
Sbjct: 823 RENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNI--GSNYPEKLSARDGHNQKDNT 880
Query: 304 DQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPV 363
+ K +++PG D G + K + NP + R + ++ +
Sbjct: 881 KSKEKESENAPG--DGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTD 938
Query: 364 YLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQA 423
L L DD T E A K + ++ R K K T++ D +
Sbjct: 939 SLFVLPSR--DDATPVRDEPMDAESITFKSVSEKDKRERD----KPKAKGDKTKRKNDGS 992
Query: 424 VVFGVDDNQDYNRPVINEKHK-DLIKDWALSSAAAVME--ERKPLT--TSGFHHSEEGTS 478
V ++ +P + K D ++ + S + + E P T T S++
Sbjct: 993 AV---SKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEK 1049
Query: 479 SSGSKRWVSQWASLAANHTRHDQEERIM-EFSAPLPLENETEISESGMTVRSTGSATSLA 537
+G+ R ++ T+ +EE++ ++S + E T E L
Sbjct: 1050 ITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKP--LD 1107
Query: 538 SQGERRRRTLPQLPNEEKSLESHRAKV----VTQRSEIGEKQDTELQEKETPTQVYQKDK 593
++GE+R+R + +K ES K+ VT+ + K+ E + E + +KDK
Sbjct: 1108 NKGEKRKRKTEE-KGVDKDFESSSMKISKLEVTEIVKPSPKRKME-PDTEKMDRTPEKDK 1165
Query: 594 QDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSL-VKQTLAKLQQ 652
P K+ +N ET K G + + + KE SE + TS VKQ K +
Sbjct: 1166 ISLSAPAKKIK--LNRETGKKIGSTENISNT------KEPSEKLESTSSKVKQEKVKGKV 1217
Query: 653 QEQREEAQWTPTKL----SSKNVSGQTDKCREE---TFKQESQPPEKNSGHSTSKGD--- 702
+ + + + + L S+ + G + EE T + + E+ + +T+ +
Sbjct: 1218 RRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVI 1277
Query: 703 ---RVAQSESKR---RKAEEILKSQTPKGGDKKESS---------KSLVR------QGSF 741
+V QS+ + EE +KS P K +S ++V+ + S
Sbjct: 1278 IMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSE 1337
Query: 742 TIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEA 801
I+K + ++ E+I H K + ++ SS + R E +P+ ++T K
Sbjct: 1338 KIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEK---- 1393
Query: 802 VMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
E+ L N+ +++ S + D AS+ T ++K+ + +
Sbjct: 1394 -----ESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREY 1448
Query: 862 TSLYK-DRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQP 920
+S + D + + KD + A + K + R D +K S R R+P
Sbjct: 1449 SSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP 1508
Query: 921 SVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHV-----HSKLEGSKV 975
H A D ++ET S + P ++HV + + G+K+
Sbjct: 1509 H------------DHKATYDTKRPNEETKSVD---KNPCKDREKHVLEARNNKESSGNKL 1553
Query: 976 TKSKTSPV-------VSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSEL-ADADKASVA 1027
P ++G KST P+P+ + +S L E ++ D +++
Sbjct: 1554 LYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSE 1613
Query: 1028 SEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAII 1087
S VS S NIS+ DL + SL + + ISR+ + S
Sbjct: 1614 SNVSVKEEESS-----GNISK-DLKDKIVEKAKESLDTAAVVQVGISRNQSHS------- 1660
Query: 1088 RSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF 1147
SP + S SR S S S T +H S+ AS++E +
Sbjct: 1661 ------------SPSV---SPSR-SHSPSGSQTRSHSSS-------------ASSAESQD 1691
Query: 1148 GSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQE 1191
+ K + + AG+ + S KH+ K+++
Sbjct: 1692 SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKK 1735
Score = 33.1 bits (74), Expect = 2.1
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 8/84 (9%)
Query: 958 PLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSE 1017
P+TS+ H + +S +P VSG+ S + P P P T+ + + E SD
Sbjct: 372 PVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSA---PAPVPDITATVSISVHSEKSDGP 428
Query: 1018 LADADK-----ASVASEVSTTSST 1036
D+D A++ASE S +S+
Sbjct: 429 FRDSDNKILPAAALASEHSKGTSS 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,945,456
Number of Sequences: 37866
Number of extensions: 2701940
Number of successful extensions: 13708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 609
Number of HSP's that attempted gapping in prelim test: 11079
Number of HSP's gapped (non-prelim): 2649
length of query: 1486
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1371
effective length of database: 13,892,928
effective search space: 19047204288
effective search space used: 19047204288
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.