Guide to the Human Genome
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Search of human proteins with 108773801

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108773801 glycine dehydrogenase (decarboxylating) [Homo
sapiens]
         (1020 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|108773801 glycine dehydrogenase (decarboxylating) [Homo sapiens]  2085   0.0  
gi|221316711 piwi-like 4 [Homo sapiens]                                35   0.36 
gi|45545409 F-box protein 38 isoform b [Homo sapiens]                  33   1.8  
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]             32   2.3  
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    32   4.0  
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C...    31   5.2  
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               31   6.8  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]       30   8.9  
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]        30   8.9  
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    30   8.9  
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    30   8.9  
gi|23821044 zinc finger/RING finger 2 [Homo sapiens]                   30   8.9  

>gi|108773801 glycine dehydrogenase (decarboxylating) [Homo sapiens]
          Length = 1020

 Score = 2085 bits (5403), Expect = 0.0
 Identities = 1020/1020 (100%), Positives = 1020/1020 (100%)

Query: 1    MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRH 60
            MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRH
Sbjct: 1    MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRH 60

Query: 61   DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATL 120
            DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATL
Sbjct: 61   DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDPVCENEILATL 120

Query: 121  HAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQ 180
            HAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQ
Sbjct: 121  HAISSKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESLLNYQ 180

Query: 181  TMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYT 240
            TMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYT
Sbjct: 181  TMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRKFLVDPRCHPQTIAVVQTRAKYT 240

Query: 241  GVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALC 300
            GVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALC
Sbjct: 241  GVLTELKLPCEMDFSGKDVSGVLFQYPDTEGKVEDFTELVERAHQSGSLACCATDLLALC 300

Query: 301  ILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEV 360
            ILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEV
Sbjct: 301  ILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEV 360

Query: 361  YRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSE 420
            YRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSE
Sbjct: 361  YRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVHNATLILSE 420

Query: 421  GLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKD 480
            GLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKD
Sbjct: 421  GLKRAGHQLQHDLFFDTLKIQCGCSVKEVLGRAAQRQINFRLFEDGTLGISLDETVNEKD 480

Query: 481  LDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKK 540
            LDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKK
Sbjct: 481  LDDLLWIFGCESSAELVAESMGEECRGIPGSVFKRTSPFLTHQVFNSYHSETNIVRYMKK 540

Query: 541  LENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEK 600
            LENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEK
Sbjct: 541  LENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQGYQQLFRELEK 600

Query: 601  DLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHM 660
            DLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHM
Sbjct: 601  DLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTVCLIPKSAHGTNPASAHM 660

Query: 661  AGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQH 720
            AGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQH
Sbjct: 661  AGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQH 720

Query: 721  GGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFL 780
            GGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFL
Sbjct: 721  GGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFL 780

Query: 781  PNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYM 840
            PNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYM
Sbjct: 781  PNHPVISLKRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYM 840

Query: 841  AKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVA 900
            AKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVA
Sbjct: 841  AKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVA 900

Query: 901  GTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW 960
            GTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW
Sbjct: 901  GTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHW 960

Query: 961  DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS 1020
            DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
Sbjct: 961  DRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS 1020


>gi|221316711 piwi-like 4 [Homo sapiens]
          Length = 852

 Score = 35.0 bits (79), Expect = 0.36
 Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 11/106 (10%)

Query: 93  KTVPANIRLKRPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLL 152
           +T+   I LKR L    PVC          I  K  +++  IG  +YN S P  I ++ L
Sbjct: 183 ETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQ--IGRNFYNPSEPMEIPQHKL 240

Query: 153 E-------NSGWITQYTPYQPEVSQG--RLESLLNYQTMVCDITGL 189
                   +  +  +   +  +VS    R E++L + T +C  TGL
Sbjct: 241 SLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGL 286


>gi|45545409 F-box protein 38 isoform b [Homo sapiens]
          Length = 1188

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 24  GGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQREMLQTLG 83
           G SGP    R+  S SG       G+S+     +  ++D+ RR +       R  L  + 
Sbjct: 824 GSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPL----TRARSRLSHVL 879

Query: 84  LASIDELIEKTVPANIRLK-----RPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGY 138
           L S  E + KT P +   +     +     DPV E++ +  L  + SKN      +G+  
Sbjct: 880 LVSESE-VAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVL-VLKSKN-----LVGVTM 932

Query: 139 YNCSVPQTILRN 150
            NC +   +L++
Sbjct: 933 TNCGITDLVLKD 944


>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
          Length = 568

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 65/296 (21%), Positives = 114/296 (38%), Gaps = 33/296 (11%)

Query: 566 SELAPITWKEFANIHPFVPLDQAQGYQQLFRELEKDLCEL-TGYDQVCFQPNSGAQGEYA 624
           +EL    + +FA  +P  P D   G +++  E+ +  C L  G    C    SG  G  +
Sbjct: 157 TELLVKAYGDFAWSNPLHP-DIFPGLRKIEAEIVRIACSLFNGGPDSCGCVTSG--GTES 213

Query: 625 GLATIRAYLNQKGE-GHRTVCLI-PKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLK 682
            L   +AY +   E G +T  ++ P+SAH     +A   GMKI  V + K   +D   ++
Sbjct: 214 ILMACKAYRDLAFEKGIKTPEIVAPQSAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMR 273

Query: 683 AMVDKHKENLAAIMITYPSTNGVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGD 742
             + ++   L      +P  +GV +  + +V  L  ++   +++D       +       
Sbjct: 274 RAISRNTAMLVCSTPQFP--HGVIDP-VPEVAKLAVKYKIPLHVDACLGGFLIVFMEKA- 329

Query: 743 FGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLAPFLPNHPVISLKRNE---------D 793
            G  + H         P      G+  I    H   + P    + L  ++         D
Sbjct: 330 -GYPLEH---------PFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQFFVD 379

Query: 794 ACPVGTVSAAPWGSSS----ILPISWAYIKMMGGKGLKQATETAILNANYMAKRLE 845
               G + A+P  + S    I    WA +   G  G  +AT+  I  A ++   LE
Sbjct: 380 TDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELE 435


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 31.6 bits (70), Expect = 4.0
 Identities = 20/38 (52%), Positives = 22/38 (57%), Gaps = 4/38 (10%)

Query: 18   GGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLER 55
            GG   AGG+ P WA   R  S GGGDS   GAS + ER
Sbjct: 1882 GGSSAAGGALP-WA---RGGSGGGGDSHHGGASYVPER 1915


>gi|20149533 Fc fragment of IgE, low affinity II, receptor for
           (CD23A) [Homo sapiens]
          Length = 321

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 37/160 (23%), Positives = 66/160 (41%), Gaps = 29/160 (18%)

Query: 789 KRNEDACPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKQATETAILNANYMAKRLETHY 848
           +R      +G V+AA W     L + W +      + LKQ  E A  N + ++K LE+H+
Sbjct: 19  RRGTQIVLLGLVTAALWAGLLTLLLLWHWDTT---QSLKQLEERAARNVSQVSKNLESHH 75

Query: 849 RILFRGARGYVGHEFILDTRPFKKSANIEAVDV-AKRLQDYGFHAPTMSWPVAGTLMVEP 907
                      G +    ++  + S  +E +    +RL+        +SW + G      
Sbjct: 76  -----------GDQMAQKSQSTQISQELEELRAEQQRLKSQDLE---LSWNLNGL----- 116

Query: 908 TESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKM 947
                +A+L  F    ++ R E +D+ E R+   V  L+M
Sbjct: 117 -----QADLSSFKSQELNERNEASDLLE-RLREEVTKLRM 150


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 30.8 bits (68), Expect = 6.8
 Identities = 19/54 (35%), Positives = 24/54 (44%)

Query: 24   GGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQRE 77
            GG GP + P  R+ S G G  AA G     E   P  + F R    P  + +RE
Sbjct: 1048 GGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRRE 1101


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 2/106 (1%)

Query: 267 PDTEGKVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGY 326
           P+    V+  T+L+ R H +  +     +L  +        F + + +   ++FG PLGY
Sbjct: 209 PNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGY 268

Query: 327 GGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHI 372
                   A RE ++R + G       + + +E+  +A +    H+
Sbjct: 269 --EDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHV 312


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 22/106 (20%), Positives = 45/106 (42%), Gaps = 2/106 (1%)

Query: 267 PDTEGKVEDFTELVERAHQSGSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGY 326
           P+    V+  T+L+ R H +  +     +L  +        F + + +   ++FG PLGY
Sbjct: 209 PNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGY 268

Query: 327 GGPHAAFFAVRESLVRMMPGRMVGVTRDATGKEVYRLALQTREQHI 372
                   A RE ++R + G       + + +E+  +A +    H+
Sbjct: 269 --EDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHV 312


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 7/87 (8%)

Query: 18  GGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQRE 77
           GG   AGG GP  A        GGG   AAGA   L      H   A   +   D+   E
Sbjct: 211 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGAL------HPHHAAGGLHFDDRFSDE 264

Query: 78  MLQTLGLASIDELIEKTVPAN-IRLKR 103
            L T+ +  ++  +        IRLK+
Sbjct: 265 QLVTMSVRELNRQLRGVSKEEVIRLKQ 291


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 7/87 (8%)

Query: 18  GGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPGDKDQRE 77
           GG   AGG GP  A        GGG   AAGA   L      H   A   +   D+   E
Sbjct: 211 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGAL------HPHHAAGGLHFDDRFSDE 264

Query: 78  MLQTLGLASIDELIEKTVPAN-IRLKR 103
            L T+ +  ++  +        IRLK+
Sbjct: 265 QLVTMSVRELNRQLRGVSKEEVIRLKQ 291


>gi|23821044 zinc finger/RING finger 2 [Homo sapiens]
          Length = 242

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 15/35 (42%), Positives = 18/35 (51%)

Query: 15 GVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGA 49
          G GG R  A G  P   P +   S+ GG +AAA A
Sbjct: 37 GGGGARAAAAGRFPAQVPSAHQPSASGGAAAAAAA 71


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,297,212
Number of Sequences: 37866
Number of extensions: 1892631
Number of successful extensions: 5218
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 5208
Number of HSP's gapped (non-prelim): 15
length of query: 1020
length of database: 18,247,518
effective HSP length: 112
effective length of query: 908
effective length of database: 14,006,526
effective search space: 12717925608
effective search space used: 12717925608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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