Guide to the Human Genome
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Search of human proteins with 108773793

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108773793 glucose-6-phosphate dehydrogenase isoform b [Homo
sapiens]
         (515 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109389365 glucose-6-phosphate dehydrogenase isoform a [Homo s...  1054   0.0  
gi|108773793 glucose-6-phosphate dehydrogenase isoform b [Homo s...  1054   0.0  
gi|52145310 hexose-6-phosphate dehydrogenase precursor [Homo sap...   224   2e-58
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    30   4.0  
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    30   4.0  
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    30   4.0  
gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]        30   5.3  
gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]              30   6.9  
gi|194097448 RELT-like 2 [Homo sapiens]                                29   9.0  
gi|194097446 RELT-like 2 [Homo sapiens]                                29   9.0  
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       29   9.0  
gi|157671949 rearranged L-myc fusion [Homo sapiens]                    29   9.0  

>gi|109389365 glucose-6-phosphate dehydrogenase isoform a [Homo
           sapiens]
          Length = 545

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL 60
           MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
Sbjct: 31  MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL 90

Query: 61  LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR 120
           LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
Sbjct: 91  LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR 150

Query: 121 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS 180
           LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
Sbjct: 151 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS 210

Query: 181 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP 240
           DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
Sbjct: 211 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP 270

Query: 241 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA 300
           FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
Sbjct: 271 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA 330

Query: 301 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK 360
           NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
Sbjct: 331 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK 390

Query: 361 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL 420
           ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
Sbjct: 391 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL 450

Query: 421 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI 480
           DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
Sbjct: 451 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI 510

Query: 481 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL 515
           PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Sbjct: 511 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL 545


>gi|108773793 glucose-6-phosphate dehydrogenase isoform b [Homo
           sapiens]
          Length = 515

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL 60
           MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
Sbjct: 1   MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL 60

Query: 61  LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR 120
           LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
Sbjct: 61  LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR 120

Query: 121 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS 180
           LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
Sbjct: 121 LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS 180

Query: 181 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP 240
           DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
Sbjct: 181 DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP 240

Query: 241 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA 300
           FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
Sbjct: 241 FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA 300

Query: 301 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK 360
           NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
Sbjct: 301 NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK 360

Query: 361 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL 420
           ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
Sbjct: 361 ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL 420

Query: 421 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI 480
           DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
Sbjct: 421 DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI 480

Query: 481 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL 515
           PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
Sbjct: 481 PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL 515


>gi|52145310 hexose-6-phosphate dehydrogenase precursor [Homo
           sapiens]
          Length = 791

 Score =  224 bits (570), Expect = 2e-58
 Identities = 156/484 (32%), Positives = 251/484 (51%), Gaps = 47/484 (9%)

Query: 35  IIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKA---- 90
           I++GA+GDLAKK ++  ++ L+ D     ++F   +  + LT    ++  E   KA    
Sbjct: 29  ILLGATGDLAKKYLWQGLFQLYLDEAGRGHSF--SFHGAALTAP--KQGQELMAKALESL 84

Query: 91  ------TPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNAL--HLG-SQANRLFYLA 141
                  P    + +D F + S    Q   A  YQ LN  + A   H G  +A R+FY +
Sbjct: 85  SCPKDMAPSHCAEHKDQFLQLSQYR-QLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFS 143

Query: 142 LPPTVYEAVTKNIHESCMSQIG-WNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRID 200
           +PP  YE + +NI+ SC    G W R+++EKPFG D  S+ +L+  + + F+E+++YR+D
Sbjct: 144 VPPFAYEDIARNINSSCRPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVD 203

Query: 201 HYLGKEMVQNLMVLRFANR-IFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDV 259
           HYLGK+ V  ++  R  NR     +WNR ++  V +  KE    EGR  +++E+G+IRDV
Sbjct: 204 HYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDV 263

Query: 260 MQNHLLQMLCLVAMEKPASTNS-DDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEA 318
           +QNHL ++L LVAME P + +S + V   K++V + +  +Q  + V+GQY        E 
Sbjct: 264 LQNHLTEVLTLVAMELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQY----QSYSEQ 319

Query: 319 TKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAG 378
            +  L  P     S T TFAAV+++++N RW+GVPFIL  GKAL+ER    R+ F + A 
Sbjct: 320 VRRELQKPD-SFHSLTPTFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQAC 378

Query: 379 DI--------FHQQCKRNELVIRVQPNE----AVYTKMMTKKPGMFFNPEESE------- 419
            +           QC   +LV  +   +    AV       +P +  + +E E       
Sbjct: 379 CVQSEKHWAAAQSQCLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRL 438

Query: 420 --LDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKP 477
               L+    Y  V+  DA+  L+  +F G +  F+ ++ L  +W  +TPLL  +  + P
Sbjct: 439 FGSPLSDYYAYSPVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAP 498

Query: 478 KPIP 481
           +  P
Sbjct: 499 RLYP 502


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 12/77 (15%)

Query: 127 ALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNH 186
           A  +  +A   F++ L  T YE +T  I ++ +  I W  ++V++        + RL N+
Sbjct: 844 AFKMKREAQVKFHVLL--TSYELIT--IDQAALGSIRWACLVVDE--------AHRLKNN 891

Query: 187 ISSLFREDQIYRIDHYL 203
            S  FR    Y+IDH L
Sbjct: 892 QSKFFRVLNGYKIDHKL 908


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 12/77 (15%)

Query: 127 ALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNH 186
           A  +  +A   F++ L  T YE +T  I ++ +  I W  ++V++        + RL N+
Sbjct: 844 AFKMKREAQVKFHVLL--TSYELIT--IDQAALGSIRWACLVVDE--------AHRLKNN 891

Query: 187 ISSLFREDQIYRIDHYL 203
            S  FR    Y+IDH L
Sbjct: 892 QSKFFRVLNGYKIDHKL 908


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 12/77 (15%)

Query: 127 ALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNH 186
           A  +  +A   F++ L  T YE +T  I ++ +  I W  ++V++        + RL N+
Sbjct: 903 AFKMKREAQVKFHVLL--TSYELIT--IDQAALGSIRWACLVVDE--------AHRLKNN 950

Query: 187 ISSLFREDQIYRIDHYL 203
            S  FR    Y+IDH L
Sbjct: 951 QSKFFRVLNGYKIDHKL 967


>gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]
          Length = 589

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 1/41 (2%)

Query: 288 KVKVLKC-ISEVQANNVVLGQYVGNPDGEGEATKGYLDDPT 327
           ++++LKC +  V +   VLG ++GN + + +  KG L D T
Sbjct: 120 EIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDAT 160


>gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]
          Length = 713

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 12/34 (35%), Positives = 23/34 (67%), Gaps = 1/34 (2%)

Query: 479 PIPYIYG-SRGPTEADELMKRVGFQYEGTYKWVN 511
           P  YI G  +GPT A+E +++ G + +G ++W++
Sbjct: 143 PSTYIEGLPQGPTTAEETVQKEGMRKQGLFQWLD 176


>gi|194097448 RELT-like 2 [Homo sapiens]
          Length = 303

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/44 (29%), Positives = 27/44 (61%), Gaps = 1/44 (2%)

Query: 282 DDVRDEKV-KVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLD 324
           DD+ ++ V ++++CI + +AN   L + +G+ +GEG      +D
Sbjct: 65  DDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVD 108


>gi|194097446 RELT-like 2 [Homo sapiens]
          Length = 303

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/44 (29%), Positives = 27/44 (61%), Gaps = 1/44 (2%)

Query: 282 DDVRDEKV-KVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLD 324
           DD+ ++ V ++++CI + +AN   L + +G+ +GEG      +D
Sbjct: 65  DDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVD 108


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 15/48 (31%), Positives = 25/48 (52%)

Query: 254 GIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQAN 301
           G    VM+  L+Q+ C  +  KPA+       D+++K +K + E  AN
Sbjct: 133 GFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDAN 180


>gi|157671949 rearranged L-myc fusion [Homo sapiens]
          Length = 1914

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 6/89 (6%)

Query: 176 DLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVIL 235
           D  SSD+LS+  S+   E+ I  +DH    E +Q+  VL    ++FGP   ++  + + +
Sbjct: 893 DSNSSDQLSHSSSASMNEELIDTLDH---SETMQD--VLLSNEKVFGPSSLKEKCSSMAV 947

Query: 236 TFKEPFGTEGRGGYFDEFGIIRDVMQNHL 264
            F     T G  G    +   R  MQ HL
Sbjct: 948 CFDGTKFTCGFDGCGSTYKNARG-MQKHL 975


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,728,778
Number of Sequences: 37866
Number of extensions: 874072
Number of successful extensions: 1527
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1515
Number of HSP's gapped (non-prelim): 15
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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