Guide to the Human Genome
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Search of human proteins with 4557625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557625 glutamate-cysteine ligase, catalytic subunit [Homo
sapiens]
         (637 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557625 glutamate-cysteine ligase, catalytic subunit [Homo sa...  1302   0.0  
gi|7662284 microtubule associated monoxygenase, calponin and LIM...    31   3.0  
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    30   5.2  
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    30   5.2  
gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens]         30   5.2  
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           30   5.2  
gi|57863271 hypothetical protein LOC23078 isoform a [Homo sapiens]     30   8.9  
gi|57863273 hypothetical protein LOC23078 isoform b [Homo sapiens]     30   8.9  

>gi|4557625 glutamate-cysteine ligase, catalytic subunit [Homo
           sapiens]
          Length = 637

 Score = 1302 bits (3369), Expect = 0.0
 Identities = 637/637 (100%), Positives = 637/637 (100%)

Query: 1   MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH 60
           MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
Sbjct: 1   MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH 60

Query: 61  ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV 120
           ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
Sbjct: 61  ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV 120

Query: 121 EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI 180
           EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI
Sbjct: 121 EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI 180

Query: 181 NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDA 240
           NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDA
Sbjct: 181 NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDA 240

Query: 241 MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI 300
           MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
Sbjct: 241 MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI 300

Query: 301 SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ 360
           SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
Sbjct: 301 SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ 360

Query: 361 EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI 420
           EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
Sbjct: 361 EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI 420

Query: 421 GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL 480
           GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
Sbjct: 421 GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL 480

Query: 481 QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS 540
           QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
Sbjct: 481 QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS 540

Query: 541 YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS 600
           YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
Sbjct: 541 YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS 600

Query: 601 LILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN 637
           LILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN
Sbjct: 601 LILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN 637


>gi|7662284 microtubule associated monoxygenase, calponin and LIM
           domain containing 2 [Homo sapiens]
          Length = 1124

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 19/89 (21%)

Query: 352 KEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRF 411
           K+ Y +     IDH+  + +  +  +  L L  E IH+               N + ++ 
Sbjct: 143 KKFYGKFCAGSIDHISIRQLQLILFKVALMLGVE-IHV---------------NVEFVKV 186

Query: 412 KPPPP---NSDIGWRVEFRPMEVQLTDFE 437
             PP    N  IGWR EF P +  L++FE
Sbjct: 187 LEPPEDQENQKIGWRAEFLPTDHSLSEFE 215


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 282 ASPFYRGY-VSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCG 340
           A  FY G+ V    C W  I+ + ++    E+    +   N+R+ KS +    SY+    
Sbjct: 9   ACSFYTGHLVKTHFCTWRDIARTNENVVLAEKMNRAVTCYNFRLQKSVFHHWHSYMEDQK 68

Query: 341 EKYNDIDLTIDKEIY 355
           EK  +I L I + IY
Sbjct: 69  EKLKNILLRIQQIIY 83


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 282 ASPFYRGY-VSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCG 340
           A  FY G+ V    C W  I+ + ++    E+    +   N+R+ KS +    SY+    
Sbjct: 9   ACSFYTGHLVKTHFCTWRDIARTNENVVLAEKMNRAVTCYNFRLQKSVFHHWHSYMEDQK 68

Query: 341 EKYNDIDLTIDKEIY 355
           EK  +I L I + IY
Sbjct: 69  EKLKNILLRIQQIIY 83


>gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens]
          Length = 1171

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 16/56 (28%), Positives = 28/56 (50%), Gaps = 6/56 (10%)

Query: 127 RRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAINK 182
           RR   T +++EN ++  ++SFP    P   LP   P P + G   ++  P + + K
Sbjct: 162 RRAHPTVLIQENGSVSAVSSFP---SPSLLLP---PQPADAGDLSTILSPIKLVQK 211


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 33  IYHAVKDRHKDV--LKWGDEVEYMLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHP 90
           +Y  + D ++ V   KW D  + ++  +  E K + +  +  K+++T QE+G      H 
Sbjct: 99  VYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELH- 157

Query: 91  TLWRPEYGSYMIEGTPGQ 108
            LWR +   ++ E T  Q
Sbjct: 158 QLWR-KLTQFLAESTEDQ 174


>gi|57863271 hypothetical protein LOC23078 isoform a [Homo sapiens]
          Length = 1905

 Score = 29.6 bits (65), Expect = 8.9
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 487 RKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENME 546
           R++I  G    +D C     +   A E  TL     I+ G E     ++P+LN+ LEN E
Sbjct: 148 RREIRAGTAFYIDQC-----AVRAATEGRTL-----ILEGLEKAERNVLPVLNNLLENRE 197

Query: 547 VDVDTRCSILN---YLKLIKKRASGEL 570
           + ++    +++   Y KL++     EL
Sbjct: 198 MQLEDGRFLMSAERYDKLLRDHTKKEL 224


>gi|57863273 hypothetical protein LOC23078 isoform b [Homo sapiens]
          Length = 1039

 Score = 29.6 bits (65), Expect = 8.9
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 487 RKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENME 546
           R++I  G    +D C     +   A E  TL     I+ G E     ++P+LN+ LEN E
Sbjct: 148 RREIRAGTAFYIDQC-----AVRAATEGRTL-----ILEGLEKAERNVLPVLNNLLENRE 197

Query: 547 VDVDTRCSILN---YLKLIKKRASGEL 570
           + ++    +++   Y KL++     EL
Sbjct: 198 MQLEDGRFLMSAERYDKLLRDHTKKEL 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,854,195
Number of Sequences: 37866
Number of extensions: 1102213
Number of successful extensions: 2548
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2547
Number of HSP's gapped (non-prelim): 8
length of query: 637
length of database: 18,247,518
effective HSP length: 109
effective length of query: 528
effective length of database: 14,120,124
effective search space: 7455425472
effective search space used: 7455425472
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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