Search of human proteins with 4557032

Search of human proteins with 4557032

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557032 L-lactate dehydrogenase B [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557032 L-lactate dehydrogenase B [Homo sapiens]                   660   0.0  
gi|5031857 L-lactate dehydrogenase A isoform 1 [Homo sapiens]         523   e-149
gi|9257228 L-lactate dehydrogenase C [Homo sapiens]                   477   e-135
gi|4504973 L-lactate dehydrogenase C [Homo sapiens]                   477   e-135
gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens]            459   e-129
gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens]           456   e-128
gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens]            456   e-128
gi|207028494 L-lactate dehydrogenase A isoform 2 [Homo sapiens]       312   2e-85
gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Hom...   230   2e-60
gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Hom...   154   8e-38
gi|21735621 mitochondrial malate dehydrogenase precursor [Homo s...    57   2e-08
gi|5174539 cytosolic malate dehydrogenase [Homo sapiens]               55   1e-07
gi|14150171 THO complex 3 [Homo sapiens]                               30   2.3  
gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartat...    29   5.2  
gi|110347568 centrosomal protein 152kDa [Homo sapiens]                 29   5.2  
gi|183227691 proline dehydrogenase 1 [Homo sapiens]                    29   6.7  
gi|37537689 zinc finger protein 354A [Homo sapiens]                    29   6.7  

>gi|4557032 L-lactate dehydrogenase B [Homo sapiens]
          Length = 334

 Score =  660 bits (1702), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK
Sbjct: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
Sbjct: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
Sbjct: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
Sbjct: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
Sbjct: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL 334
           LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
Sbjct: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL 334


>gi|5031857 L-lactate dehydrogenase A isoform 1 [Homo sapiens]
          Length = 332

 Score =  523 bits (1347), Expect = e-149
 Identities = 251/332 (75%), Positives = 296/332 (89%), Gaps = 1/332 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           MATLK++LI  + +EE T P NKITVVGVG VGMACAISIL K LADELALVDV+EDKLK
Sbjct: 1   MATLKDQLIYNLLKEEQT-PQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLK 59

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GEMMDLQHGSLFL+TPKIV+ KDY+VTANSK+V++TAG RQQEGESRLNLVQRNVN+FKF
Sbjct: 60  GEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKF 119

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           IIP +VKYSP+C +++VSNPVDILTYV WK+SG PK+RVIGSGCNLDSARFRYLM E+LG
Sbjct: 120 IIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLG 179

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           +HP SCHGW+LGEHGDSSV VWSG+NVAGVSL+ L+P++GTD D E WKEVHK VVESAY
Sbjct: 180 VHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAY 239

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           EVIKLKGYT+WAIGLSVADL ES++KNL R+HPVSTM+KG+YGI+++VFLS+PCIL   G
Sbjct: 240 EVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNG 299

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332
           ++ ++   L  +E A+LKKSADTLW IQK+L+
Sbjct: 300 ISDLVKVTLTSEEEARLKKSADTLWGIQKELQ 331


>gi|9257228 L-lactate dehydrogenase C [Homo sapiens]
          Length = 332

 Score =  477 bits (1228), Expect = e-135
 Identities = 231/331 (69%), Positives = 278/331 (83%), Gaps = 1/331 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           M+T+KE+LI  + E++      KIT+VG G VGMACAISIL K LADELALVDV  DKLK
Sbjct: 1   MSTVKEQLIEKLIEDDEN-SQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLK 59

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GEMMDLQHGSLF  T KI + KDYSV+ANS+IV+VTAG RQQEGE+RL LVQRNV + K 
Sbjct: 60  GEMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKS 119

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           IIP IV YSPDC I+VVSNPVDILTY+ WK+SGLP  RVIGSGCNLDSARFRYL+ EKLG
Sbjct: 120 IIPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLG 179

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           +HP+SCHGWI+GEHGDSSV +WSGVNVAGV+L+ L+P++GTD+D E+WK +HK V++SAY
Sbjct: 180 VHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAY 239

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           E+IKLKGYT+WAIGLSV DL+ S+LKNL R+HPVSTMVKG+YGI+ E+FLS+PC+L   G
Sbjct: 240 EIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNG 299

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDL 331
           ++ V+   L  +E A  KKSA+TLW+IQKDL
Sbjct: 300 VSDVVKINLNSEEEALFKKSAETLWNIQKDL 330


>gi|4504973 L-lactate dehydrogenase C [Homo sapiens]
          Length = 332

 Score =  477 bits (1228), Expect = e-135
 Identities = 231/331 (69%), Positives = 278/331 (83%), Gaps = 1/331 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           M+T+KE+LI  + E++      KIT+VG G VGMACAISIL K LADELALVDV  DKLK
Sbjct: 1   MSTVKEQLIEKLIEDDEN-SQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLK 59

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GEMMDLQHGSLF  T KI + KDYSV+ANS+IV+VTAG RQQEGE+RL LVQRNV + K 
Sbjct: 60  GEMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKS 119

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           IIP IV YSPDC I+VVSNPVDILTY+ WK+SGLP  RVIGSGCNLDSARFRYL+ EKLG
Sbjct: 120 IIPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLG 179

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           +HP+SCHGWI+GEHGDSSV +WSGVNVAGV+L+ L+P++GTD+D E+WK +HK V++SAY
Sbjct: 180 VHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAY 239

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           E+IKLKGYT+WAIGLSV DL+ S+LKNL R+HPVSTMVKG+YGI+ E+FLS+PC+L   G
Sbjct: 240 EIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNG 299

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDL 331
           ++ V+   L  +E A  KKSA+TLW+IQKDL
Sbjct: 300 VSDVVKINLNSEEEALFKKSAETLWNIQKDL 330


>gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens]
          Length = 381

 Score =  459 bits (1181), Expect = e-129
 Identities = 222/332 (66%), Positives = 271/332 (81%), Gaps = 1/332 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           MAT+K +LI     E+  V ++K++++G G VGMACAISIL K L+DELALVD+ EDKLK
Sbjct: 50  MATVKSELIERFTSEKP-VHHSKVSIIGTGSVGMACAISILLKGLSDELALVDLDEDKLK 108

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GE MDLQHGS F + P IV  KDY VTANS +V++TAG RQ++GE+RLNLVQRNV +FK 
Sbjct: 109 GETMDLQHGSPFTKMPNIVCSKDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKL 168

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           +I  IV+YSP C +I+VSNPVDILTYV WKLS  PK+R+IGSGCNLD+ARFR+L+ +KLG
Sbjct: 169 MISSIVQYSPHCKLIIVSNPVDILTYVAWKLSAFPKNRIIGSGCNLDTARFRFLIGQKLG 228

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           IH  SCHGWILGEHGDSSV VWSGVN+AGV L++LN ++GTD D E WK VHK V  +AY
Sbjct: 229 IHSESCHGWILGEHGDSSVPVWSGVNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAY 288

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           E+IK+KGYT+WAIGLSVADL ES+LKNL RIHPVST++KG+YGI+ EVFLS+PCIL   G
Sbjct: 289 EIIKMKGYTSWAIGLSVADLTESILKNLRRIHPVSTIIKGLYGIDEEVFLSIPCILGENG 348

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332
           +T++I  KL  +E A LKKSA TLW+IQ  LK
Sbjct: 349 ITNLIKIKLTPEEEAHLKKSAKTLWEIQNKLK 380


>gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens]
          Length = 332

 Score =  456 bits (1172), Expect = e-128
 Identities = 218/332 (65%), Positives = 273/332 (82%), Gaps = 1/332 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           MAT+K +LI   AEEEA + +NKI++VG G VG+ACAISIL K L+DEL LVDV E KLK
Sbjct: 1   MATIKSELIKNFAEEEA-IHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLK 59

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GE MDLQHGS F++ P IV+ KDY VTANS +V++TAG RQ++GE+RL+LVQRNV++FK 
Sbjct: 60  GETMDLQHGSPFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKL 119

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           +IP I +YSP C +++V+NPVDILTYV WKLSG PK+RVIGSGCNLDSARFRY + ++LG
Sbjct: 120 MIPNITQYSPHCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLG 179

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           IH  SCHG ILGEHGDSSV VWSGVN+AGV L++LNP++GTD D E W+ VHK V+ S Y
Sbjct: 180 IHSESCHGLILGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGY 239

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           E++K+KGYT+W I LSVADL ES+LKNL R+HPVST+ KG+YGI  ++FLS+PCIL   G
Sbjct: 240 EMVKMKGYTSWGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENG 299

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332
           +T +I  KL  +E A L+KSA+TLW+IQK+LK
Sbjct: 300 ITDLIKVKLTLEEEACLQKSAETLWEIQKELK 331


>gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens]
          Length = 332

 Score =  456 bits (1172), Expect = e-128
 Identities = 218/332 (65%), Positives = 273/332 (82%), Gaps = 1/332 (0%)

Query: 1   MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
           MAT+K +LI   AEEEA + +NKI++VG G VG+ACAISIL K L+DEL LVDV E KLK
Sbjct: 1   MATIKSELIKNFAEEEA-IHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLK 59

Query: 61  GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF 120
           GE MDLQHGS F++ P IV+ KDY VTANS +V++TAG RQ++GE+RL+LVQRNV++FK 
Sbjct: 60  GETMDLQHGSPFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKL 119

Query: 121 IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG 180
           +IP I +YSP C +++V+NPVDILTYV WKLSG PK+RVIGSGCNLDSARFRY + ++LG
Sbjct: 120 MIPNITQYSPHCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLG 179

Query: 181 IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY 240
           IH  SCHG ILGEHGDSSV VWSGVN+AGV L++LNP++GTD D E W+ VHK V+ S Y
Sbjct: 180 IHSESCHGLILGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGY 239

Query: 241 EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG 300
           E++K+KGYT+W I LSVADL ES+LKNL R+HPVST+ KG+YGI  ++FLS+PCIL   G
Sbjct: 240 EMVKMKGYTSWGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENG 299

Query: 301 LTSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332
           +T +I  KL  +E A L+KSA+TLW+IQK+LK
Sbjct: 300 ITDLIKVKLTLEEEACLQKSAETLWEIQKELK 331


>gi|207028494 L-lactate dehydrogenase A isoform 2 [Homo sapiens]
          Length = 274

 Score =  312 bits (800), Expect = 2e-85
 Identities = 143/197 (72%), Positives = 172/197 (87%)

Query: 136 VVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHG 195
           +VS  VDILTYV WK+SG PK+RVIGSGCNLDSARFRYLM E+LG+HP SCHGW+LGEHG
Sbjct: 77  IVSGKVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHG 136

Query: 196 DSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGL 255
           DSSV VWSG+NVAGVSL+ L+P++GTD D E WKEVHK VVESAYEVIKLKGYT+WAIGL
Sbjct: 137 DSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGL 196

Query: 256 SVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVA 315
           SVADL ES++KNL R+HPVSTM+KG+YGI+++VFLS+PCIL   G++ ++   L  +E A
Sbjct: 197 SVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEA 256

Query: 316 QLKKSADTLWDIQKDLK 332
           +LKKSADTLW IQK+L+
Sbjct: 257 RLKKSADTLWGIQKELQ 273



 Score =  121 bits (304), Expect = 8e-28
 Identities = 65/82 (79%), Positives = 72/82 (87%), Gaps = 1/82 (1%)

Query: 1  MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK 60
          MATLK++LI  + +EE T P NKITVVGVG VGMACAISIL K LADELALVDV+EDKLK
Sbjct: 1  MATLKDQLIYNLLKEEQT-PQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLK 59

Query: 61 GEMMDLQHGSLFLQTPKIVADK 82
          GEMMDLQHGSLFL+TPKIV+ K
Sbjct: 60 GEMMDLQHGSLFLRTPKIVSGK 81


>gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Homo
           sapiens]
          Length = 471

 Score =  230 bits (586), Expect = 2e-60
 Identities = 126/314 (40%), Positives = 190/314 (60%), Gaps = 29/314 (9%)

Query: 22  NKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81
           NKITVVG G++G+AC ++I  K +AD L L+D L +  KG  MDL+  +L    P +   
Sbjct: 183 NKITVVGGGELGIACTLAISAKGIADRLVLLD-LSEGTKGATMDLEIFNL----PNVEIS 237

Query: 82  KDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPV 141
           KD S +A+SK+V+ T        +S L++VQ NV++F+ ++P +  YS   +++V S PV
Sbjct: 238 KDLSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPV 296

Query: 142 DILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAV 201
           +I+TYVTWKLS  P +RVIG GCNLDS R +Y++   L    S    W++GE G+  V  
Sbjct: 297 EIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLT 356

Query: 202 WSGVN--VAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVAD 259
           WSG    V+  S  +L+                      A E++++KG  +W++GLSVAD
Sbjct: 357 WSGQEEVVSHTSQVQLS--------------------NRAMELLRVKGQRSWSVGLSVAD 396

Query: 260 LIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQ-LK 318
           +++S++ N  ++H VS + KG Y I +EVFLSLPCIL   G++ VI   LK+D V + L+
Sbjct: 397 MVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQ 456

Query: 319 KSADTLWDIQKDLK 332
            SA ++  +Q+ LK
Sbjct: 457 SSASSIHSLQQQLK 470


>gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Homo
           sapiens]
          Length = 379

 Score =  154 bits (390), Expect = 8e-38
 Identities = 80/183 (43%), Positives = 116/183 (63%), Gaps = 6/183 (3%)

Query: 22  NKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81
           NKITVVG G++G+AC ++I  K +AD L L+D L +  KG  MDL+  +L    P +   
Sbjct: 183 NKITVVGGGELGIACTLAISAKGIADRLVLLD-LSEGTKGATMDLEIFNL----PNVEIS 237

Query: 82  KDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPV 141
           KD S +A+SK+V+ T        +S L++VQ NV++F+ ++P +  YS   +++V S PV
Sbjct: 238 KDLSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPV 296

Query: 142 DILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAV 201
           +I+TYVTWKLS  P +RVIG GCNLDS R +Y++   L    S    W++GE G+  V  
Sbjct: 297 EIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLT 356

Query: 202 WSG 204
           WSG
Sbjct: 357 WSG 359


>gi|21735621 mitochondrial malate dehydrogenase precursor [Homo
           sapiens]
          Length = 338

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 75/337 (22%), Positives = 136/337 (40%), Gaps = 47/337 (13%)

Query: 21  NNKITVVGV-GQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIV 79
           N K+ V+G  G +G   ++ +    L   L L D+      G   DL H    ++T   V
Sbjct: 24  NAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTP--GVAADLSH----IETKAAV 77

Query: 80  ADKDY-------SVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDC 132
             K Y              +VV+ AGV ++ G +R +L   N  +   +     ++ P+ 
Sbjct: 78  --KGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEA 135

Query: 133 IIIVVSNPVDI---LTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGW 189
           +I V++NPV+    +T   +K  G+     I     LD  R    +AE  G+ P+  +  
Sbjct: 136 MICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVP 195

Query: 190 ILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLK--- 246
           ++G H   ++            + +  P++  D   +    +   + E+  EV+K K   
Sbjct: 196 VIGGHAGKTII---------PLISQCTPKV--DFPQDQLTALTGRIQEAGTEVVKAKAGA 244

Query: 247 GYTNWAIGLSVADLIESMLKNLSRIHPV--STMVKGMYGIENE-VFLSLPCILNARGL-- 301
           G    ++  + A  + S++  ++    V   + VK     E E  + S P +L  +G+  
Sbjct: 245 GSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ---ETECTYFSTPLLLGKKGIEK 301

Query: 302 ------TSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332
                  S   +K+  D + +LK S     D  K LK
Sbjct: 302 NLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK 338


>gi|5174539 cytosolic malate dehydrogenase [Homo sapiens]
          Length = 334

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 67/271 (24%), Positives = 117/271 (43%), Gaps = 19/271 (7%)

Query: 39  SILGKSLADELALVDV--LEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVT 96
           S+ GK     L L+D+  +   L G +M+LQ  +L L    I  DK+     +  + ++ 
Sbjct: 28  SVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILV 87

Query: 97  AGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCI-IIVVSNPVDILTYVTWKLS-GL 154
             + ++EG  R +L++ NV +FK     + KY+   + +IVV NP +       K +  +
Sbjct: 88  GSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSI 147

Query: 155 PKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQ- 213
           PK         LD  R +  +A KLG+  +     I+   G+ S   +  VN A V LQ 
Sbjct: 148 PKEN-FSCLTRLDHNRAKAQIALKLGVTANDVKNVII--WGNHSSTQYPDVNHAKVKLQG 204

Query: 214 -ELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIH 272
            E+       +DS    E    V +    VIK +  ++    +S A  I   ++++    
Sbjct: 205 KEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSS---AMSAAKAICDHVRDIWFGT 261

Query: 273 PVSTMVK-------GMYGIENEVFLSLPCIL 296
           P    V          YG+ +++  S P ++
Sbjct: 262 PEGEFVSMGVISDGNSYGVPDDLLYSFPVVI 292


>gi|14150171 THO complex 3 [Homo sapiens]
          Length = 351

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%)

Query: 29  VGQVGMACAISILGKSLADELALVDVLE-DKLKGEMMDLQHGSLFLQTPKIVADKDYSVT 87
           V  V  +C    L     D+ A V +LE D+L  E     HG    Q     ++ D  VT
Sbjct: 58  VHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVT 117

Query: 88  ANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYV 147
           A+    +    VR  +  + +N    N+N+          +SPD   I V N  D++T++
Sbjct: 118 ASGDKTIRIWDVRTTKCIATVNTKGENINIC---------WSPDGQTIAVGNKDDVVTFI 168

Query: 148 TWK 150
             K
Sbjct: 169 DAK 171


>gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartate
           3A [Homo sapiens]
          Length = 1115

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 26/158 (16%)

Query: 60  KGEMMDLQHGSLFLQTPKIVADK-----------------DYSVTANSKIVVVTAGVRQQ 102
           +GEMM+L   SL L  P I   +                 + S+++++ + V    +   
Sbjct: 203 QGEMMELDLVSLVLHIPVISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNW 262

Query: 103 EGESRLNLVQRNVNVFKFII--PQIVKYSPDCIIIVVSN---PVDILTYVTWKLSGLPKH 157
              S L L Q + N+  F++      K+    II + +N     D+L+++  +L  +   
Sbjct: 263 YNFSLL-LCQEDWNITDFLLLTQNNSKFHLGSIINITANLPSTQDLLSFLQIQLESIKNS 321

Query: 158 --RVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGE 193
              V+  GC+++S R  + +  + G+ P     W+LG+
Sbjct: 322 TPTVVMFGCDMESIRRIFEITTQFGVMPPELR-WVLGD 358


>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
          Length = 1654

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 52/222 (23%), Positives = 85/222 (38%), Gaps = 45/222 (20%)

Query: 40  ILGKSLADELALVDVLEDKLKGEMMDL-----------QHGSLFLQTPKIVADKDYSVTA 88
           ++ KS   E+AL     + LK +++DL           QH S+ +   K   ++  S+  
Sbjct: 325 MIKKSRTTEMAL-----ESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVLSLQK 379

Query: 89  NSKIVVVTAGVRQQEGESRLN----LVQRNVNVFKFIIPQIV--------KYSPDCIIIV 136
           N     VTA   Q++  SRL      ++RN    K    +I+        +    C  ++
Sbjct: 380 NLD-ATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINKLTRSLEESQKQCAHLL 438

Query: 137 VSNPVDILTYVTWKLSGLPKHRVIGSGCN---------LDSARFRYLMAEKLGIHPSSCH 187
            S  V  +  + ++L    K   + +  N         L      Y  A KLGIHPS   
Sbjct: 439 QSGSVQEVAQLQFQLQQAQKAHAMSANMNKALQEELTELKDEISLYESAAKLGIHPSDSE 498

Query: 188 GWILGEHGDSSVAV------WSGVNVAGVSLQE-LNPEMGTD 222
           G +  E  +S V +      W    V  +  +E  N E+  D
Sbjct: 499 GELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNEELSKD 540


>gi|183227691 proline dehydrogenase 1 [Homo sapiens]
          Length = 600

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 15/41 (36%), Positives = 23/41 (56%)

Query: 144 LTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPS 184
           L YV  +L    K +V+ +  N D+ RF     E+LG+HP+
Sbjct: 478 LDYVLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPA 518


>gi|37537689 zinc finger protein 354A [Homo sapiens]
          Length = 605

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 14/38 (36%), Positives = 20/38 (52%)

Query: 66  LQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQE 103
           L+  S  L  PKI ADK Y  +   K  + T+ +R+ E
Sbjct: 196 LKQNSQLLNQPKITADKRYKCSLCEKTFINTSSLRKHE 233


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,428,365
Number of Sequences: 37866
Number of extensions: 462883
Number of successful extensions: 1009
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 985
Number of HSP's gapped (non-prelim): 18
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.