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Search of human proteins with 4557010
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557010 acid phosphatase 2, lysosomal isoform 1 precursor
[Homo sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557010 acid phosphatase 2, lysosomal isoform 1 precursor [Ho... 872 0.0
gi|197116348 acid phosphatase, prostate long isoform precursor [... 388 e-108
gi|6382064 acid phosphatase, prostate short isoform precursor [H... 380 e-105
gi|14861860 testicular acid phosphatase precursor [Homo sapiens] 320 2e-87
gi|197100230 acid phosphatase 2, lysosomal isoform 2 [Homo sapiens] 316 3e-86
gi|151301213 acid phosphatase 6, lysophosphatidic [Homo sapiens] 92 7e-19
gi|81295410 acid phosphatase-like 2 [Homo sapiens] 57 4e-08
gi|22748649 acid phosphatase-like 2 [Homo sapiens] 57 4e-08
gi|156104886 CC chemokine receptor 10 [Homo sapiens] 30 4.1
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 30 5.4
gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens] 29 7.1
gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprot... 29 7.1
gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprot... 29 7.1
gi|46409657 WD repeat domain 56 [Homo sapiens] 29 7.1
gi|21389523 leucine zipper-EF-hand containing transmembrane prot... 29 7.1
gi|4503057 crystallin, alpha B [Homo sapiens] 29 9.2
gi|25952134 dispatched A [Homo sapiens] 29 9.2
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 29 9.2
gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 29 9.2
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 29 9.2
>gi|4557010 acid phosphatase 2, lysosomal isoform 1 precursor [Homo
sapiens]
Length = 423
Score = 872 bits (2253), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE 60
MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE
Sbjct: 1 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE 60
Query: 61 WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG 120
WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG
Sbjct: 61 WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG 120
Query: 121 LFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESS 180
LFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESS
Sbjct: 121 LFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESS 180
Query: 181 RNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSF 240
RNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSF
Sbjct: 181 RNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSF 240
Query: 241 RFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVY 300
RFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVY
Sbjct: 241 RFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVY 300
Query: 301 NGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEP 360
NGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEP
Sbjct: 301 NGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEP 360
Query: 361 VVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGE 420
VVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGE
Sbjct: 361 VVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGE 420
Query: 421 DHA 423
DHA
Sbjct: 421 DHA 423
>gi|197116348 acid phosphatase, prostate long isoform precursor
[Homo sapiens]
Length = 418
Score = 388 bits (996), Expect = e-108
Identities = 186/374 (49%), Positives = 251/374 (67%), Gaps = 2/374 (0%)
Query: 30 ARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHG 89
A+ L+FVTL++RHGDRSP+ T+P DP +E WPQGFGQLT+ GM QH+ELG+ +R+RY
Sbjct: 32 AKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRK 91
Query: 90 FLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITED 149
FLN SY ++VY+RSTD DRTLMSA NLA LFPP G+ +NP + WQPIPVHTVP++ED
Sbjct: 92 FLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSED 151
Query: 150 RLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWN-VYD 208
+LL P CPR+++L++ET ++ E+Q F+ + +GL L +W+ VYD
Sbjct: 152 QLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYD 211
Query: 209 TLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNL 268
L+CE H LP WA+ TM +L L + S L+GI++Q EK+RLQGGVL+ +I ++
Sbjct: 212 PLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHM 271
Query: 269 TLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMY 328
KL++YSAHDTT+ LQMALDVYNG PYASCH+ ELY E G + VEMY
Sbjct: 272 KRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE-KGEYFVEMY 330
Query: 329 FRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVC 388
+RNE+ P+PL LPGC CPL+ F L PV+P+DW EC + +VI A+A C
Sbjct: 331 YRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQVLKVIFAVAFC 390
Query: 389 GSILFLLIVLLLTV 402
L+++L + +
Sbjct: 391 LISAVLMVLLFIHI 404
>gi|6382064 acid phosphatase, prostate short isoform precursor [Homo
sapiens]
Length = 386
Score = 380 bits (977), Expect = e-105
Identities = 181/352 (51%), Positives = 239/352 (67%), Gaps = 2/352 (0%)
Query: 30 ARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHG 89
A+ L+FVTL++RHGDRSP+ T+P DP +E WPQGFGQLT+ GM QH+ELG+ +R+RY
Sbjct: 32 AKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRK 91
Query: 90 FLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITED 149
FLN SY ++VY+RSTD DRTLMSA NLA LFPP G+ +NP + WQPIPVHTVP++ED
Sbjct: 92 FLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSED 151
Query: 150 RLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWN-VYD 208
+LL P CPR+++L++ET ++ E+Q F+ + +GL L +W+ VYD
Sbjct: 152 QLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYD 211
Query: 209 TLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNL 268
L+CE H LP WA+ TM +L L + S L+GI++Q EK+RLQGGVL+ +I ++
Sbjct: 212 PLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHM 271
Query: 269 TLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMY 328
KL++YSAHDTT+ LQMALDVYNG PYASCH+ ELY E G + VEMY
Sbjct: 272 KRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE-KGEYFVEMY 330
Query: 329 FRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTE 380
+RNE+ P+PL LPGC CPL+ F L PV+P+DW EC + TE
Sbjct: 331 YRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTE 382
>gi|14861860 testicular acid phosphatase precursor [Homo sapiens]
Length = 426
Score = 320 bits (819), Expect = 2e-87
Identities = 183/404 (45%), Positives = 240/404 (59%), Gaps = 22/404 (5%)
Query: 1 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARS--LRFVTLLYRHGDRSPVKTYPKDPYQE 58
MAG A L LLL L+V+PP L FV L++RHGDR+P+ +YP DP++E
Sbjct: 1 MAGLGFWGHPAGPLLLLL---LLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE 57
Query: 59 EE---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAE 115
WP+G GQLT EG+ Q ELG+ LR RY FL+ Y R+EVY+RSTDFDRTL SA+
Sbjct: 58 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ 117
Query: 116 ANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEY 175
ANLAGLFP +P W+PIPVHTVP+ ED+LL+FP+ CPRY +L E + EY
Sbjct: 118 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY 175
Query: 176 QNESSRNAQFLDMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLS 233
Q FL + N TGL+ + L W V DTL C+Q HGL LP WASP ++ L+
Sbjct: 176 QEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLA 235
Query: 234 RLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVAL 293
++ G + AEKA+L GG+LL I N + + K+++YSAHD+TL+AL
Sbjct: 236 QISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLAL 295
Query: 294 QMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPGCPH 347
Q AL +Y+G PYA+C FE + +D GN +V +++RN+S P PLSLPGCP
Sbjct: 296 QGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPA 355
Query: 348 RCPLQDFLRLTEPVVPKDWQQEC----QLASGPADTEVIVALAV 387
CPL F +LT P P C + A PA ++A AV
Sbjct: 356 PCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAV 399
>gi|197100230 acid phosphatase 2, lysosomal isoform 2 [Homo sapiens]
Length = 160
Score = 316 bits (809), Expect = 3e-86
Identities = 150/151 (99%), Positives = 151/151 (100%)
Query: 1 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE 60
MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE
Sbjct: 1 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEE 60
Query: 61 WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG 120
WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG
Sbjct: 61 WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAG 120
Query: 121 LFPPNGMQRFNPNISWQPIPVHTVPITEDRL 151
LFPPNGMQRFNPNISWQPIPVHTVPITEDR+
Sbjct: 121 LFPPNGMQRFNPNISWQPIPVHTVPITEDRV 151
>gi|151301213 acid phosphatase 6, lysophosphatidic [Homo sapiens]
Length = 428
Score = 92.4 bits (228), Expect = 7e-19
Identities = 101/373 (27%), Positives = 152/373 (40%), Gaps = 73/373 (19%)
Query: 33 LRFVTLLYRHGDRSPVKTYPKDPYQEEEW-----------------------PQGF---- 65
L+ V +++RHG RSP+K P + ++ EW P+ +
Sbjct: 50 LKMVQVVFRHGARSPLKPLPLE--EQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYD 107
Query: 66 --------------GQLTKEGMLQHWELGQALRQRYHG---FLNTSYHRQEVYVRSTDFD 108
GQLTK GM Q + LG+ LR+ Y FL+ +++ QEV++RST+
Sbjct: 108 SQYHETTLKGGMFAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFNPQEVFIRSTNIF 167
Query: 109 RTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNE 168
R L S LAGLF PI +HT + +L C Q
Sbjct: 168 RNLESTRCLLAGLFQCQ---------KEGPIIIHTDE-ADSEVLYPNYQSCWSLRQRTRG 217
Query: 169 TRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQT 228
RQT Q S + L V + G+ + + D + EQ H L P
Sbjct: 218 RRQTASLQPGISED---LKKVKDRMGIDSSDKVDFFILLDNVAAEQAHNLPSCPMLKRFA 274
Query: 229 MQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP----KLLVYS 284
R D S L + E ++ G L + NL ++ P KL +Y+
Sbjct: 275 RMIEQRAVDTSLYIL--PKEDRESLQMAVGPFLHILESNLLKAVDSATAPDKIRKLYLYA 332
Query: 285 AHDTTLVALQMALDVYNGEQAPYASCHIFELYQE-DSGNFSVEMYFRNESDKAPWPLSLP 343
AHD T + L M L +++ + P+A ELYQ +S + V++Y+ + ++ P
Sbjct: 333 AHDVTFIPLLMTLGIFDHKWPPFAVDLTMELYQHLESKEWFVQLYYHGK-EQVP-----R 386
Query: 344 GCPH-RCPLQDFL 355
GCP CPL FL
Sbjct: 387 GCPDGLCPLDMFL 399
>gi|81295410 acid phosphatase-like 2 [Homo sapiens]
Length = 480
Score = 56.6 bits (135), Expect = 4e-08
Identities = 82/335 (24%), Positives = 132/335 (39%), Gaps = 57/335 (17%)
Query: 51 YPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRY---HGFLNTSYHRQEVYVRSTDF 107
YP P E G+LT+ G++QH + GQ LR Y H L + ++Y+ +T
Sbjct: 154 YPNHPLCE------MGELTQTGVVQHLQNGQLLRDIYLKKHKLLPNDWSADQLYLETTGK 207
Query: 108 DRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPC---PRYEQ 164
RTL S A L G F P+ W+ I P F G C R +
Sbjct: 208 SRTLQSGLALLYG---------FLPDFDWKKIYFRHQPSA-----LFCSGSCYCPVRNQY 253
Query: 165 LQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWA 224
L+ E R+ + ++S+ + +A + L N D++ C H + P
Sbjct: 254 LEKEQRRQYLLRLKNSQLEKTYGEMAKIVDVPTKQLRAA-NPIDSMLCHFCHNVSFP--C 310
Query: 225 SPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLL-AQIRKNLTL----MATTSQLPK 279
+ + K + ++ EK G LL A N T+ AT + +
Sbjct: 311 TRNGCVDMEHFKVIKTHQIEDERERREKKLYFGYSLLGAHPILNQTIGRMQRATEGRKEE 370
Query: 280 LL-VYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQ--EDSGNFSVEMYF------- 329
L +YSAHD TL + AL + +A+ IFEL+Q E SV + +
Sbjct: 371 LFALYSAHDVTLSPVLSALGLSEARFPRFAARLIFELWQDREKPSEHSVRILYNGVDVTF 430
Query: 330 -----RNESDKAPWPLSLPGCPHRCPLQDFLRLTE 359
++ ++P P+ CPL++ +R +
Sbjct: 431 HTSFCQDHHKRSPKPM--------CPLENLVRFVK 457
>gi|22748649 acid phosphatase-like 2 [Homo sapiens]
Length = 480
Score = 56.6 bits (135), Expect = 4e-08
Identities = 82/335 (24%), Positives = 132/335 (39%), Gaps = 57/335 (17%)
Query: 51 YPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRY---HGFLNTSYHRQEVYVRSTDF 107
YP P E G+LT+ G++QH + GQ LR Y H L + ++Y+ +T
Sbjct: 154 YPNHPLCE------MGELTQTGVVQHLQNGQLLRDIYLKKHKLLPNDWSADQLYLETTGK 207
Query: 108 DRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPC---PRYEQ 164
RTL S A L G F P+ W+ I P F G C R +
Sbjct: 208 SRTLQSGLALLYG---------FLPDFDWKKIYFRHQPSA-----LFCSGSCYCPVRNQY 253
Query: 165 LQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWA 224
L+ E R+ + ++S+ + +A + L N D++ C H + P
Sbjct: 254 LEKEQRRQYLLRLKNSQLEKTYGEMAKIVDVPTKQLRAA-NPIDSMLCHFCHNVSFP--C 310
Query: 225 SPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLL-AQIRKNLTL----MATTSQLPK 279
+ + K + ++ EK G LL A N T+ AT + +
Sbjct: 311 TRNGCVDMEHFKVIKTHQIEDERERREKKLYFGYSLLGAHPILNQTIGRMQRATEGRKEE 370
Query: 280 LL-VYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQ--EDSGNFSVEMYF------- 329
L +YSAHD TL + AL + +A+ IFEL+Q E SV + +
Sbjct: 371 LFALYSAHDVTLSPVLSALGLSEARFPRFAARLIFELWQDREKPSEHSVRILYNGVDVTF 430
Query: 330 -----RNESDKAPWPLSLPGCPHRCPLQDFLRLTE 359
++ ++P P+ CPL++ +R +
Sbjct: 431 HTSFCQDHHKRSPKPM--------CPLENLVRFVK 457
>gi|156104886 CC chemokine receptor 10 [Homo sapiens]
Length = 362
Score = 30.0 bits (66), Expect = 4.1
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 72 GMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFP 123
G LQ W LG A + G + S+H +++ DR + A A AG P
Sbjct: 101 GALQGWSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRP 152
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 29.6 bits (65), Expect = 5.4
Identities = 37/156 (23%), Positives = 57/156 (36%), Gaps = 18/156 (11%)
Query: 59 EEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTD-FDRTL---MSA 114
+E G L E + QH E+ + Q+ H N + YV D D+ +
Sbjct: 179 QERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLE 238
Query: 115 EANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPE 174
EAN G FP + + NIS ++ + L P E+ E TP
Sbjct: 239 EAN-RGSFPAEMVNKIFSNIS-------SINAFHSKFL------LPELEKRMQEWETTPR 284
Query: 175 YQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTL 210
+ + A FL M D +E V N+ + +
Sbjct: 285 IGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERI 320
>gi|21493033 A-kinase anchor protein 10 precursor [Homo sapiens]
Length = 662
Score = 29.3 bits (64), Expect = 7.1
Identities = 19/86 (22%), Positives = 37/86 (43%)
Query: 135 SWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETG 194
+W I H++ + L P+ P ++E + + + + E S +AQ +
Sbjct: 165 TWSRIRAHSLNTVKQSSLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGID 224
Query: 195 LTDLTLETVWNVYDTLFCEQTHGLRL 220
L + T T ++ + C+ H LRL
Sbjct: 225 LNNRTNSTQNHLLLSQECDSAHSLRL 250
>gi|19923395 beta-site APP-cleaving enzyme 2 isoform A preproprotein
[Homo sapiens]
Length = 518
Score = 29.3 bits (64), Expect = 7.1
Identities = 15/26 (57%), Positives = 21/26 (80%), Gaps = 1/26 (3%)
Query: 385 LAVCGSILFLLIVLLLTVLFRMQAQP 410
++VCG+IL +LIVLLL + FR Q +P
Sbjct: 476 MSVCGAILLVLIVLLL-LPFRCQRRP 500
>gi|21040360 beta-site APP-cleaving enzyme 2 isoform C preproprotein
[Homo sapiens]
Length = 468
Score = 29.3 bits (64), Expect = 7.1
Identities = 15/26 (57%), Positives = 21/26 (80%), Gaps = 1/26 (3%)
Query: 385 LAVCGSILFLLIVLLLTVLFRMQAQP 410
++VCG+IL +LIVLLL + FR Q +P
Sbjct: 426 MSVCGAILLVLIVLLL-LPFRCQRRP 450
>gi|46409657 WD repeat domain 56 [Homo sapiens]
Length = 777
Score = 29.3 bits (64), Expect = 7.1
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 245 GIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAH-DTTLVALQMALDVYNGE 303
G Q+AE LQ G++ I+ N+ L L + Y H DT L Q L+ + +
Sbjct: 670 GNIQEAEIVLLQAGLVYQAIQININLYNWERALELAVKYKTHVDTVLAYRQKFLETFGKQ 729
Query: 304 QAPYASCHIFELYQED 319
+ H E Q D
Sbjct: 730 ETNKRYLHYAEGLQID 745
>gi|21389523 leucine zipper-EF-hand containing transmembrane protein
2 [Homo sapiens]
Length = 396
Score = 29.3 bits (64), Expect = 7.1
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 137 QPIPVHTVPITEDRLLKFPLGPCPRYEQ--LQNETRQTPEYQNESSRNA 183
QP PV + PIT + P GP E+ LQ +++ T + SS+ A
Sbjct: 348 QPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMTAQNSKASSKGA 396
>gi|4503057 crystallin, alpha B [Homo sapiens]
Length = 175
Score = 28.9 bits (63), Expect = 9.2
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 84 RQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHT 143
RQ HGF++ +HR+ Y D D +++ + G+ NG ++ +S P T
Sbjct: 107 RQDEHGFISREFHRK--YRIPADVDPLTITSSLSSDGVLTVNGPRK---QVSG---PERT 158
Query: 144 VPITED 149
+PIT +
Sbjct: 159 IPITRE 164
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 28.9 bits (63), Expect = 9.2
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 9/55 (16%)
Query: 334 DKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVC 388
D P LP C H CP P+ QEC +GPA ALA C
Sbjct: 70 DNQRMPQMLPQCCHPCPYH------HPLTSHSSHQECHPEAGPAAPS---ALASC 115
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 28.9 bits (63), Expect = 9.2
Identities = 11/25 (44%), Positives = 15/25 (60%)
Query: 320 SGNFSVEMYFRNESDKAPWPLSLPG 344
S +FS ++YFR + WP LPG
Sbjct: 124 SPSFSAQLYFRPTIQRGQWPPGLPG 148
>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
sapiens]
Length = 246
Score = 28.9 bits (63), Expect = 9.2
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 382 IVALAVCGSILF-----LLIVLLLTVLFRMQAQPPGYRHV 416
I ++AV S+LF L+VL T +AQPP Y H+
Sbjct: 21 IASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHI 60
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 28.9 bits (63), Expect = 9.2
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 382 IVALAVCGSILF-----LLIVLLLTVLFRMQAQPPGYRHV 416
I ++AV S+LF L+VL T +AQPP Y H+
Sbjct: 63 IASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHI 102
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,229,837
Number of Sequences: 37866
Number of extensions: 784406
Number of successful extensions: 1720
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1693
Number of HSP's gapped (non-prelim): 25
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.