Guide to the Human Genome
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Search of human proteins with 45505167

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505167 immunoglobulin superfamily, member 1 isoform 1
[Homo sapiens]
         (1336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo...  2776   0.0  
gi|45505169 immunoglobulin superfamily, member 1 isoform 2 [Homo...   473   e-133
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (...   209   1e-53
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A...   201   3e-51
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B...   200   9e-51
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B...   200   9e-51
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A...   196   1e-49
gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]            184   4e-46
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B...   182   2e-45
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ...   181   3e-45
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B...   178   4e-44
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B...   178   4e-44
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m...   178   4e-44
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (...   177   5e-44
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ...   177   6e-44
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B...   172   2e-42
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B...   172   2e-42
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B...   172   3e-42
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B...   172   3e-42
gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]   146   1e-34
gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens]   144   6e-34
gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens]   144   7e-34
gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens]   144   7e-34
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B...   140   1e-32
gi|46488946 killer cell immunoglobulin-like receptor, three doma...   130   1e-29
gi|208879429 hypothetical LOC441864 [Homo sapiens]                    128   3e-29
gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like...   119   1e-26
gi|134268644 killer cell immunoglobulin-like receptor, three dom...   118   4e-26
gi|134133244 killer cell immunoglobulin-like receptor, three dom...   117   6e-26
gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]      117   6e-26

>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
            sapiens]
          Length = 1336

 Score = 2776 bits (7196), Expect = 0.0
 Identities = 1336/1336 (100%), Positives = 1336/1336 (100%)

Query: 1    MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60
            MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS
Sbjct: 1    MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60

Query: 61   PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120
            PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV
Sbjct: 61   PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120

Query: 121  LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180
            LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT
Sbjct: 121  LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180

Query: 181  MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240
            MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP
Sbjct: 181  MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240

Query: 241  GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD 300
            GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD
Sbjct: 241  GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD 300

Query: 301  ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360
            ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED
Sbjct: 301  ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360

Query: 361  KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420
            KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK
Sbjct: 361  KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420

Query: 421  PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG 480
            PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG
Sbjct: 421  PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG 480

Query: 481  TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540
            TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR
Sbjct: 481  TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540

Query: 541  WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF 600
            WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF
Sbjct: 541  WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF 600

Query: 601  PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC 660
            PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC
Sbjct: 601  PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC 660

Query: 661  HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ 720
            HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ
Sbjct: 661  HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ 720

Query: 721  EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF 780
            EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF
Sbjct: 721  EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF 780

Query: 781  FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG 840
            FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG
Sbjct: 781  FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG 840

Query: 841  IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900
            IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ
Sbjct: 841  IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900

Query: 901  GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL 960
            GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL
Sbjct: 901  GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL 960

Query: 961  MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND 1020
            MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND
Sbjct: 961  MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND 1020

Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080
            GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG
Sbjct: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080

Query: 1081 ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140
            ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS
Sbjct: 1081 ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE 1200
            TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE
Sbjct: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE 1200

Query: 1201 APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG 1260
            APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG
Sbjct: 1201 APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG 1260

Query: 1261 NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS 1320
            NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS
Sbjct: 1261 NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS 1320

Query: 1321 PSSTSQRISVELPVPI 1336
            PSSTSQRISVELPVPI
Sbjct: 1321 PSSTSQRISVELPVPI 1336


>gi|45505169 immunoglobulin superfamily, member 1 isoform 2 [Homo
           sapiens]
          Length = 242

 Score =  473 bits (1216), Expect = e-133
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60
           MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS
Sbjct: 1   MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60

Query: 61  PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120
           PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV
Sbjct: 61  PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120

Query: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180
           LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT
Sbjct: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180

Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG 223
           MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG
Sbjct: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG 223



 Score =  187 bits (476), Expect = 4e-47
 Identities = 101/238 (42%), Positives = 138/238 (57%), Gaps = 10/238 (4%)

Query: 558 QGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSG 617
           +G TML   T LL    C  + +  T IVM  P+PELW E+N+P APW+N+TLWCRSPS 
Sbjct: 8   EGATMLKTFTVLL---FCIRMSLGMTSIVMD-PQPELWIESNYPQAPWENITLWCRSPSR 63

Query: 618 STKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALEL 677
            + +F+LLKD T     RP+ +  + +F +GALT+S+ G Y C  W+E   S+PS+ LEL
Sbjct: 64  ISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLEL 123

Query: 678 VGTDILPKPVI---SASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAF 734
                LPKP+    + +P + G  + + C GWL  + F L+KEG  EPV      G  A 
Sbjct: 124 EAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAI 183

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           F+I  +  +DEG Y CRTH +  P  WSEPS PL+LV+        +  W   +V PG
Sbjct: 184 FSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGGCG---YGCWHLAIVVPG 238



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 61/189 (32%), Positives = 92/189 (48%), Gaps = 4/189 (2%)

Query: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVH-GVGYILHKEGEATSMQLWGSTSNDGAFPITN 1027
            P+P L+ E +      +N+TLWCR P      ++L K+    +       +   +F I  
Sbjct: 36   PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 1028 ISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087
            ++ ++ G Y CCY   W  +   +PS  LEL   G LPKP    Q      PG N+ + C
Sbjct: 96   LTESNAGLYRCCY---WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152

Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147
             G L D  F+L KEG  EP++ Q P+G  A F +  +  ED G+Y C  ++   P   S 
Sbjct: 153  HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212

Query: 1148 HSDSLEIWV 1156
             S+ L++ V
Sbjct: 213  PSNPLKLVV 221



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 57/192 (29%), Positives = 90/192 (46%), Gaps = 8/192 (4%)

Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELP-DSTFVLLKEGAQEPLEQQRPSGYRADFWMPA 1123
            P+P L  +     AP EN+TL C+      S F+LLK+  Q    +     ++  F + A
Sbjct: 36   PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 1124 VRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183
            +   ++G+Y C Y+ ++     S  S  LE+    + PKP       T    G ++ + C
Sbjct: 96   LTESNAGLYRCCYWKET---GWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152

Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSEDGD----FVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239
             G L  + F+L  +G   P  +         F I+N+  +  G Y C   +Q  P +WSE
Sbjct: 153  HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212

Query: 1240 PSDPLELVGAAG 1251
            PS+PL+LV A G
Sbjct: 213  PSNPLKLVVAGG 224



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 55/193 (28%), Positives = 86/193 (44%), Gaps = 8/193 (4%)

Query: 775 MYPKPFFKTWASPVVTPGARVTFNCSTPHQHMS-FILYKDGSEIASSDRSWASPGASA-- 831
           M P+P     ++    P   +T  C +P +  S F+L KD +++     +W  P      
Sbjct: 34  MDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQM-----TWIRPSHKTFQ 88

Query: 832 AHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891
             FLI ++   + G Y C Y+  + WS+PS  +EL      PKP    Q      PG +V
Sbjct: 89  VSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNV 148

Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSN 951
            + C G  Q + F L +EG   P+ ++  +G  A F +  +  ED G Y C  +   +  
Sbjct: 149 NILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPT 208

Query: 952 RGSYLSMPLMIWV 964
             S  S PL + V
Sbjct: 209 LWSEPSNPLKLVV 221



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 4/191 (2%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQ-GMRFALLQEGAHVPLQFRSVSGNSADFLLHT 931
            P+P L  +      P +++ L C+   +   +F LL++   +     S       FL+  
Sbjct: 36   PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 932  VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991
            +   ++G Y C Y++ T  ++ S +   L +      PKP  + +  +    G NV + C
Sbjct: 96   LTESNAGLYRCCYWKETGWSKPSKV---LELEAPGQLPKPIFWIQAETPALPGCNVNILC 152

Query: 992  RGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQ 1051
             G +  + ++L KEG A  +     T     F I N++    G Y C  H     ++  +
Sbjct: 153  HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212

Query: 1052 PSNTLELLVTG 1062
            PSN L+L+V G
Sbjct: 213  PSNPLKLVVAG 223



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 9/137 (6%)

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F I  + + + G Y C    E     WS+PS+ LEL      PKP F   A     PG  
Sbjct: 91  FLIGALTESNAGLYRCCYWKETG---WSKPSKVLELEAPGQLPKPIFWIQAETPALPGCN 147

Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYYDF 854
           V   C    Q + F+L+K+G    +    +  P  + A F I ++   D G Y CR +  
Sbjct: 148 VNILCHGWLQDLVFMLFKEG---YAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204

Query: 855 ---SIWSEPSDPVELVV 868
              ++WSEPS+P++LVV
Sbjct: 205 MLPTLWSEPSNPLKLVV 221



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 46/168 (27%), Positives = 67/168 (39%), Gaps = 5/168 (2%)

Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQ-DLVFMLFKEGYAEPVDYQVPTGTMAIFSIDN 188
           P+P  WI++  P  P  N+ + C    +    F+L K+                 F I  
Sbjct: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 189 LTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248
           LT  + G+Y C        T WS+PS  L+L   G  PKP           PG ++N+ C
Sbjct: 96  LTESNAGLYRC---CYWKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152

Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLC 296
            G +  + F L +    E   Y   T    A F   +L  +D G Y+C
Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFSIDNLTPEDEGVYIC 199



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 54/209 (25%), Positives = 84/209 (40%), Gaps = 14/209 (6%)

Query: 316 VTDTFPKTWLLAR-PSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDN 374
           V D  P+ W+ +  P A     +N++L CR P       L  K + + + ++  +     
Sbjct: 33  VMDPQPELWIESNYPQAP---WENITLWCRSPSRISSKFLLLKDKTQ-MTWIRPSHKTFQ 88

Query: 375 TSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLG 434
            SF +  +T S+ G+Y C Y   WK +        +EL    + PKP       T    G
Sbjct: 89  VSFLIGALTESNAGLYRCCY---WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPG 145

Query: 435 KAITLQCRVSHPVLEFSLEWEERETFQKFSVNGD----FIISNVDGKGTGTYSCSYRVET 490
             + + C      L F L  E       + V       F I N+  +  G Y C   ++ 
Sbjct: 146 CNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQM 205

Query: 491 HPNIWSHRSEPLKLM--GPAGYLTWNYVL 517
            P +WS  S PLKL+  G  GY  W+  +
Sbjct: 206 LPTLWSEPSNPLKLVVAGGCGYGCWHLAI 234



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 7/191 (3%)

Query: 226 PKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQS 285
           P+P L        AP E++ L C+ P    +  L+  +  + ++        + +F   +
Sbjct: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 286 LKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKT--WLLARPSAVVQMGQNVSLRC 343
           L   + G Y C Y+  +   S  S VL++      PK   W+ A   A+   G NV++ C
Sbjct: 96  LTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKPIFWIQAETPALP--GCNVNILC 152

Query: 344 RGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIR 403
            G +  +   L+K+G  +P+ +   T       F ++N+T  D G+Y C   +    ++ 
Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIFSIDNLTPEDEGVYICRTHIQMLPTLW 210

Query: 404 MPSHNTVELMV 414
               N ++L+V
Sbjct: 211 SEPSNPLKLVV 221


>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (with
            TM domain), member 2 isoform b [Homo sapiens]
          Length = 466

 Score =  209 bits (533), Expect = 1e-53
 Identities = 155/428 (36%), Positives = 210/428 (49%), Gaps = 25/428 (5%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFR-SVSGNSADFLLHT 931
            PKPTL A+PG V+  G  V LRCQG+ Q   + L +E        R    G +  F + +
Sbjct: 27   PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIPS 86

Query: 932  VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991
            +  E +G Y C YY     N  S  S PL + VT  + KP L A PS VV +G NVTL C
Sbjct: 87   ITWEHAGRYHCQYYS---HNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQC 143

Query: 992  RGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWTS 1046
               V   G+IL KEGE    Q   S S+        F +  +S +    Y C  +   + 
Sbjct: 144  VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSP 203

Query: 1047 SIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG---- 1102
             +   PS+ LELLV G+  KPSL  QPGPMVAPGE++TLQC  ++    FVL KEG    
Sbjct: 204  YVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDF 263

Query: 1103 AQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDK-PP 1161
             Q P  Q +    +A+F +  V     G Y C Y   +     S  SD L+I +T +   
Sbjct: 264  LQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQFYD 322

Query: 1162 KPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDGDFVI 1213
            +PSLS  P      GK++TL C+       F+L  +G   P        Q      +F +
Sbjct: 323  RPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRM 382

Query: 1214 NNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAA--GPVAQECTVGNIVRSSLIVVV 1271
              V    +G Y C   L + P + S PSDPLELV +A  G   Q+ TV N++R  +  +V
Sbjct: 383  GPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTVENLIRMGVAGLV 442

Query: 1272 VVALGVVL 1279
            +V LG++L
Sbjct: 443  LVVLGILL 450



 Score =  193 bits (491), Expect = 8e-49
 Identities = 138/413 (33%), Positives = 198/413 (47%), Gaps = 25/413 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+  S   +E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYH 59

Query: 624 LLKDGTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682
           L ++       R   E  +   FP+ ++T  H G YHC  +     SE S+ LELV T  
Sbjct: 60  LYRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGRE-----AF 734
             KP +SA P+     G  + L+C   +A  GF L KEGE E  Q+L +         A 
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F++  +      +Y C  +    P+ WS PS+ LEL++  +  KP       P+V PG  
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239

Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSW-ASPGASAAHFLIISVGIGDGGNYSC--RY 851
           +T  C +   +  F+LYK+G         W    G S A+F +  V    GG Y C   +
Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299

Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910
              S WS PSDP+++++T +FY +P+L  QP P V PGK+V L CQ   Q   F L +EG
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359

Query: 911 A-HVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959
           A H PL  RS      N A+F +  V +   G Y C    +++S+    LS+P
Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCY---SSLSSNPYLLSLP 409



 Score =  169 bits (428), Expect = 2e-41
 Identities = 142/399 (35%), Positives = 190/399 (47%), Gaps = 25/399 (6%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+  G+ VT  C    Q   + LY++    AS  R    PG +   F
Sbjct: 27   PKPTL--WAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS-ASWVRRIQEPGKNG-QF 82

Query: 835  LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894
             I S+     G Y C+YY  +  SE SDP+ELVVT  Y KPTL A P PVV  G +V L+
Sbjct: 83   PIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQ 142

Query: 895  C--QGTFQGMRFALLQEGA-HVPLQFRSVS----GNSADFLLHTVGAEDSGNYSCIYYET 947
            C  Q  F G  F L +EG    P +  S S     + A F +  V      +Y C  Y++
Sbjct: 143  CVSQVAFDG--FILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200

Query: 948  TMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE 1007
                  S  S  L + V     KP L  +P  +V  G+++TL C   V    ++L+KEGE
Sbjct: 201  NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260

Query: 1008 ATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG- 1062
               +Q  G     G     F +  +S +  G+Y  CY     SS    PS+ L++L+TG 
Sbjct: 261  RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYR-CYSAHNLSSEWSAPSDPLDILITGQ 319

Query: 1063 LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRAD 1118
               +PSL  QP P VAPG+N+TL CQ      TF+L KEGA  P      + +    +A+
Sbjct: 320  FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379

Query: 1119 FWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
            F M  V     G Y C   L S P+  S  SD LE+ V+
Sbjct: 380  FRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418



 Score =  131 bits (329), Expect = 5e-30
 Identities = 114/412 (27%), Positives = 184/412 (44%), Gaps = 17/412 (4%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+  S  + ++ L ++  
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYHLYRENK 65

Query: 76  QMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134
             +W+R   +  +   F I ++T  +AG Y C Y+     S+ S  LEL   G   KP  
Sbjct: 66  SASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTL 125

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSIDNL 189
                     G NV + C   +    F+L KEG  E              + AIFS+  +
Sbjct: 126 SALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPV 185

Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQ 249
           +P     Y C  +    P +WS PS+ L+L+V G+  KP+L+  PGP++APGESL L+C 
Sbjct: 186 SPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCV 245

Query: 250 GPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASYRG 305
             +    F L +  +   L++  +  +   ++ANF    +     G Y C+  ++ S   
Sbjct: 246 SDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEW 305

Query: 306 SLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ 364
           S  SD L I +T  F  +  L  +P   V  G+NV+L C+         L K+G   P  
Sbjct: 306 SAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPL 365

Query: 365 FL--DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
            L  +  +  +   F +  VT +  G Y C+  L+    +     + +EL+V
Sbjct: 366 HLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVV 417



 Score =  127 bits (319), Expect = 7e-29
 Identities = 123/442 (27%), Positives = 192/442 (43%), Gaps = 46/442 (10%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFS 185
           G LPKP  W +  +  + G  V + C G LQ   + L++E  +     ++   G    F 
Sbjct: 24  GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83

Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245
           I ++T E  G Y C+ +        SE S+PL+LVV G Y KPTL+A P P++  G ++ 
Sbjct: 84  IPSITWEHAGRYHCQYYSHNHS---SEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140

Query: 246 LRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLCF 297
           L+C   +    F L +  + E    H + + + ++    S  I   G         Y C+
Sbjct: 141 LQCVSQVAFDGFILCKEGEDE----HPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCY 196

Query: 298 YYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALY 355
            YD++  Y  SL SD+L++ V     K  L  +P  +V  G++++L+C   V      LY
Sbjct: 197 AYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLY 256

Query: 356 KKGEDKPLQF--LDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELM 413
           K+GE   LQ       +     +F L  V+ S  G Y C+      +    PS     L+
Sbjct: 257 KEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILI 316

Query: 414 VVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERET 459
                 +PSLS  P      GK +TL C+                HP L    E + ++ 
Sbjct: 317 TGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN 376

Query: 460 FQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPA--GYLTWNYVL 517
                   +F +  V     GTY C   + ++P + S  S+PL+L+  A  G    +Y +
Sbjct: 377 ------QAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTV 430

Query: 518 NEAIRLSLIMQLVALLLVVLWI 539
              IR    M +  L+LVVL I
Sbjct: 431 ENLIR----MGVAGLVLVVLGI 448



 Score =  106 bits (265), Expect = 1e-22
 Identities = 91/301 (30%), Positives = 129/301 (42%), Gaps = 13/301 (4%)

Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTI 275
           P   V AG  PKPTL A PG ++  G  + LRCQG +    + L R           +  
Sbjct: 17  PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEP 76

Query: 276 KNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQM 335
                F   S+  +  G Y C YY  ++  S  SD L++ VT  + K  L A PS VV +
Sbjct: 77  GKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTGAYSKPTLSALPSPVVTL 135

Query: 336 GQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSC 392
           G NV+L+C   V   G  L K+GED+  Q L++ S     S   F +  V+ S    Y C
Sbjct: 136 GGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRC 195

Query: 393 HYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL 452
           +   +    +     + +EL+V     KPSLS  P  +   G+++TLQC        F L
Sbjct: 196 YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVL 255

Query: 453 EWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKL 504
             E    F        Q      +F +  V     G Y C Y      + WS  S+PL +
Sbjct: 256 YKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDI 314

Query: 505 M 505
           +
Sbjct: 315 L 315



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 71/197 (36%), Positives = 104/197 (52%), Gaps = 15/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP-LEQQRPSGYRADFW 1120
            G LPKP+L A+PG ++  G  +TL+CQG L    + L +E      + + +  G    F 
Sbjct: 24   GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83

Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180
            +P++  E +G Y C YY  +    +S +SD LE+ VT    KP+LSA PS +  LG ++T
Sbjct: 84   IPSITWEHAGRYHCQYYSHN---HSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140

Query: 1181 LQCRGPLPGVEFVLEHDGE-EAPQQFSEDG-----DFVINNVEGKGIGNYSCSYRLQAY- 1233
            LQC   +    F+L  +GE E PQ+ +         + I +V G    +   SYR  AY 
Sbjct: 141  LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSV-GPVSPSRRWSYRCYAYD 199

Query: 1234 ---PDIWSEPSDPLELV 1247
               P +WS PSD LEL+
Sbjct: 200  SNSPYVWSLPSDLLELL 216



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 65/210 (30%), Positives = 96/210 (45%), Gaps = 19/210 (9%)

Query: 37  QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92
           +P L ++     AP E++TL C S      +F+L K    D  Q    +P     Q +F 
Sbjct: 223 KPSLSVQPGPMVAPGESLTLQCVSDVGYD-RFVLYKEGERDFLQRPGWQPQAGLSQANFT 281

Query: 93  IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQL-PKPIFWIQAETPALPGCNVN 149
           +G ++ S+ G YRC   +   + WS PS  L++   GQ   +P   +Q      PG NV 
Sbjct: 282 LGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVT 341

Query: 150 ILCHGWLQDLVFMLFKEGYAEPV-----DYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204
           +LC    Q   F+L KEG   P      ++Q      A F +  +T    G Y C + + 
Sbjct: 342 LLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN-QAEFRMGPVTSAHVGTYRCYSSLS 400

Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP 234
             P L S PS+PL+LVV+      +L  HP
Sbjct: 401 SNPYLLSLPSDPLELVVSA-----SLGQHP 425



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 64/208 (30%), Positives = 98/208 (47%), Gaps = 23/208 (11%)

Query: 584 EIVMP--TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-------GWIAT 634
           E+++P  + KP L  +    +AP ++LTL C S  G  + FVL K+G        GW   
Sbjct: 214 ELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDR-FVLYKEGERDFLQRPGW--- 269

Query: 635 RPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV--SEPSEALELVGT-DILPKPVISAS 691
           +P +   +A F LG ++ SH G Y C+S   ++   S PS+ L+++ T     +P +S  
Sbjct: 270 QPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQ 329

Query: 692 PT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGREAFFTIQRMEDKD 744
           P      G+ + L C+       F L KEG   P   L     A   +A F +  +    
Sbjct: 330 PVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAH 389

Query: 745 EGNYSCRTHTEKRPFKWSEPSEPLELVI 772
            G Y C +     P+  S PS+PLELV+
Sbjct: 390 VGTYRCYSSLSSNPYLLSLPSDPLELVV 417


>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
            (with TM domain), member 2 isoform a [Homo sapiens]
          Length = 483

 Score =  201 bits (512), Expect = 3e-51
 Identities = 154/445 (34%), Positives = 209/445 (46%), Gaps = 42/445 (9%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFR-SVSGNSADFLLHT 931
            PKPTL A+PG V+  G  V LRCQG+ Q   + L +E        R    G +  F + +
Sbjct: 27   PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIPS 86

Query: 932  VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991
            +  E +G Y C YY     N  S  S PL + VT  + KP L A PS VV +G NVTL C
Sbjct: 87   ITWEHAGRYHCQYYS---HNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQC 143

Query: 992  RGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWTS 1046
               V   G+IL KEGE    Q   S S+        F +  +S +    Y C  +   + 
Sbjct: 144  VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSP 203

Query: 1047 SIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG---- 1102
             +   PS+ LELLV G+  KPSL  QPGPMVAPGE++TLQC  ++    FVL KEG    
Sbjct: 204  YVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDF 263

Query: 1103 AQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDK-PP 1161
             Q P  Q +    +A+F +  V     G Y C Y   +     S  SD L+I +T +   
Sbjct: 264  LQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQFYD 322

Query: 1162 KPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDGDFVI 1213
            +PSLS  P      GK++TL C+       F+L  +G   P        Q      +F +
Sbjct: 323  RPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRM 382

Query: 1214 NNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-------------------GAAGPVA 1254
              V    +G Y C   L + P + S PSDPLELV                    + G   
Sbjct: 383  GPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHP 442

Query: 1255 QECTVGNIVRSSLIVVVVVALGVVL 1279
            Q+ TV N++R  +  +V+V LG++L
Sbjct: 443  QDYTVENLIRMGVAGLVLVVLGILL 467



 Score =  193 bits (491), Expect = 8e-49
 Identities = 138/413 (33%), Positives = 198/413 (47%), Gaps = 25/413 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+  S   +E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYH 59

Query: 624 LLKDGTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682
           L ++       R   E  +   FP+ ++T  H G YHC  +     SE S+ LELV T  
Sbjct: 60  LYRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGRE-----AF 734
             KP +SA P+     G  + L+C   +A  GF L KEGE E  Q+L +         A 
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F++  +      +Y C  +    P+ WS PS+ LEL++  +  KP       P+V PG  
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239

Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSW-ASPGASAAHFLIISVGIGDGGNYSC--RY 851
           +T  C +   +  F+LYK+G         W    G S A+F +  V    GG Y C   +
Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299

Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910
              S WS PSDP+++++T +FY +P+L  QP P V PGK+V L CQ   Q   F L +EG
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359

Query: 911 A-HVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959
           A H PL  RS      N A+F +  V +   G Y C    +++S+    LS+P
Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCY---SSLSSNPYLLSLP 409



 Score =  172 bits (437), Expect = 1e-42
 Identities = 148/421 (35%), Positives = 200/421 (47%), Gaps = 27/421 (6%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+  G+ VT  C    Q   + LY++    AS  R    PG +   F
Sbjct: 27   PKPTL--WAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS-ASWVRRIQEPGKNG-QF 82

Query: 835  LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894
             I S+     G Y C+YY  +  SE SDP+ELVVT  Y KPTL A P PVV  G +V L+
Sbjct: 83   PIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQ 142

Query: 895  C--QGTFQGMRFALLQEGA-HVPLQFRSVS----GNSADFLLHTVGAEDSGNYSCIYYET 947
            C  Q  F G  F L +EG    P +  S S     + A F +  V      +Y C  Y++
Sbjct: 143  CVSQVAFDG--FILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200

Query: 948  TMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE 1007
                  S  S  L + V     KP L  +P  +V  G+++TL C   V    ++L+KEGE
Sbjct: 201  NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260

Query: 1008 ATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG- 1062
               +Q  G     G     F +  +S +  G+Y  CY     SS    PS+ L++L+TG 
Sbjct: 261  RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYR-CYSAHNLSSEWSAPSDPLDILITGQ 319

Query: 1063 LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRAD 1118
               +PSL  QP P VAPG+N+TL CQ      TF+L KEGA  P      + +    +A+
Sbjct: 320  FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379

Query: 1119 FWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD--KPPKPSLSAWPSTMFKLG 1176
            F M  V     G Y C   L S P+  S  SD LE+ V++  +   PS +   ST   LG
Sbjct: 380  FRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLG 439

Query: 1177 K 1177
            +
Sbjct: 440  Q 440



 Score =  134 bits (337), Expect = 6e-31
 Identities = 120/435 (27%), Positives = 194/435 (44%), Gaps = 19/435 (4%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+  S  + ++ L ++  
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYHLYRENK 65

Query: 76  QMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134
             +W+R   +  +   F I ++T  +AG Y C Y+     S+ S  LEL   G   KP  
Sbjct: 66  SASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTL 125

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSIDNL 189
                     G NV + C   +    F+L KEG  E              + AIFS+  +
Sbjct: 126 SALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPV 185

Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQ 249
           +P     Y C  +    P +WS PS+ L+L+V G+  KP+L+  PGP++APGESL L+C 
Sbjct: 186 SPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCV 245

Query: 250 GPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASYRG 305
             +    F L +  +   L++  +  +   ++ANF    +     G Y C+  ++ S   
Sbjct: 246 SDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEW 305

Query: 306 SLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ 364
           S  SD L I +T  F  +  L  +P   V  G+NV+L C+         L K+G   P  
Sbjct: 306 SAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPL 365

Query: 365 FL--DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVD--KPPK 420
            L  +  +  +   F +  VT +  G Y C+  L+    +     + +EL+V +  +   
Sbjct: 366 HLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLS 425

Query: 421 PSLSAWPSTVFKLGK 435
           PS +   ST   LG+
Sbjct: 426 PSQNKTDSTTTSLGQ 440



 Score =  121 bits (304), Expect = 4e-27
 Identities = 111/406 (27%), Positives = 176/406 (43%), Gaps = 40/406 (9%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFS 185
           G LPKP  W +  +  + G  V + C G LQ   + L++E  +     ++   G    F 
Sbjct: 24  GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83

Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245
           I ++T E  G Y C+ +        SE S+PL+LVV G Y KPTL+A P P++  G ++ 
Sbjct: 84  IPSITWEHAGRYHCQYYSHNHS---SEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140

Query: 246 LRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLCF 297
           L+C   +    F L +  + E    H + + + ++    S  I   G         Y C+
Sbjct: 141 LQCVSQVAFDGFILCKEGEDE----HPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCY 196

Query: 298 YYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALY 355
            YD++  Y  SL SD+L++ V     K  L  +P  +V  G++++L+C   V      LY
Sbjct: 197 AYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLY 256

Query: 356 KKGEDKPLQF--LDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELM 413
           K+GE   LQ       +     +F L  V+ S  G Y C+      +    PS     L+
Sbjct: 257 KEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILI 316

Query: 414 VVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERET 459
                 +PSLS  P      GK +TL C+                HP L    E + ++ 
Sbjct: 317 TGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN 376

Query: 460 FQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
                   +F +  V     GTY C   + ++P + S  S+PL+L+
Sbjct: 377 ------QAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELV 416



 Score =  106 bits (265), Expect = 1e-22
 Identities = 91/301 (30%), Positives = 129/301 (42%), Gaps = 13/301 (4%)

Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTI 275
           P   V AG  PKPTL A PG ++  G  + LRCQG +    + L R           +  
Sbjct: 17  PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEP 76

Query: 276 KNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQM 335
                F   S+  +  G Y C YY  ++  S  SD L++ VT  + K  L A PS VV +
Sbjct: 77  GKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTGAYSKPTLSALPSPVVTL 135

Query: 336 GQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSC 392
           G NV+L+C   V   G  L K+GED+  Q L++ S     S   F +  V+ S    Y C
Sbjct: 136 GGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRC 195

Query: 393 HYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL 452
           +   +    +     + +EL+V     KPSLS  P  +   G+++TLQC        F L
Sbjct: 196 YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVL 255

Query: 453 EWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKL 504
             E    F        Q      +F +  V     G Y C Y      + WS  S+PL +
Sbjct: 256 YKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDI 314

Query: 505 M 505
           +
Sbjct: 315 L 315



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 71/197 (36%), Positives = 104/197 (52%), Gaps = 15/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP-LEQQRPSGYRADFW 1120
            G LPKP+L A+PG ++  G  +TL+CQG L    + L +E      + + +  G    F 
Sbjct: 24   GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83

Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180
            +P++  E +G Y C YY  +    +S +SD LE+ VT    KP+LSA PS +  LG ++T
Sbjct: 84   IPSITWEHAGRYHCQYYSHN---HSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140

Query: 1181 LQCRGPLPGVEFVLEHDGE-EAPQQFSEDG-----DFVINNVEGKGIGNYSCSYRLQAY- 1233
            LQC   +    F+L  +GE E PQ+ +         + I +V G    +   SYR  AY 
Sbjct: 141  LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSV-GPVSPSRRWSYRCYAYD 199

Query: 1234 ---PDIWSEPSDPLELV 1247
               P +WS PSD LEL+
Sbjct: 200  SNSPYVWSLPSDLLELL 216



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 23/210 (10%)

Query: 584 EIVMP--TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-------GWIAT 634
           E+++P  + KP L  +    +AP ++LTL C S  G  + FVL K+G        GW   
Sbjct: 214 ELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDR-FVLYKEGERDFLQRPGW--- 269

Query: 635 RPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV--SEPSEALELVGT-DILPKPVISAS 691
           +P +   +A F LG ++ SH G Y C+S   ++   S PS+ L+++ T     +P +S  
Sbjct: 270 QPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQ 329

Query: 692 PT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGREAFFTIQRMEDKD 744
           P      G+ + L C+       F L KEG   P   L     A   +A F +  +    
Sbjct: 330 PVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAH 389

Query: 745 EGNYSCRTHTEKRPFKWSEPSEPLELVIKE 774
            G Y C +     P+  S PS+PLELV+ E
Sbjct: 390 VGTYRCYSSLSSNPYLLSLPSDPLELVVSE 419



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 56/198 (28%), Positives = 86/198 (43%), Gaps = 17/198 (8%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDD-NTSFFL 379
           PK  L A P +V+  G  V+LRC+G +      LY+  E+K   ++        N  F +
Sbjct: 27  PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYR--ENKSASWVRRIQEPGKNGQFPI 84

Query: 380 NNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
            ++T+   G Y C Y   +  +      + +EL+V     KP+LSA PS V  LG  +TL
Sbjct: 85  PSITWEHAGRYHCQY---YSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTL 141

Query: 440 QCRVSHPVLEFSLEWEERETFQKFSVNGD----------FIISNVDGKGTGTYSCSYRVE 489
           QC VS    +  +  +E E      +N            F +  V      +Y C     
Sbjct: 142 QC-VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200

Query: 490 THPNIWSHRSEPLKLMGP 507
             P +WS  S+ L+L+ P
Sbjct: 201 NSPYVWSLPSDLLELLVP 218


>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 1 [Homo sapiens]
          Length = 632

 Score =  200 bits (508), Expect = 9e-51
 Identities = 139/416 (33%), Positives = 204/416 (49%), Gaps = 32/416 (7%)

Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624
           +TALLC GL  G     T +   P PKP LWAE    ++    +T+WC+  S   +E+ L
Sbjct: 5   LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRL 60

Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682
            K+G+     R  P   + +A F + ++T+ H G Y CH +     SEPS+ LE+V T  
Sbjct: 61  HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734
             KP +SA P+     G  + LRC        F L KEGE +       QQL + G +A 
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F +  +       ++C  +    P+ WS PS+PLE++   +  KP   T   PV+ PG  
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851
           +T  C +   +  F+LYK+G  +           G S A+F +  V   +GG Y C   +
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300

Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910
              S WS PSDP+ +++  + Y   +L AQPGP V  G++V L CQ  +Q   F L +EG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360

Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962
            AH PL+ RS+ G     A+F +  V +  +G Y C          GSY S P ++
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY---------GSYSSNPHLL 407



 Score =  182 bits (463), Expect = 1e-45
 Identities = 140/398 (35%), Positives = 191/398 (47%), Gaps = 20/398 (5%)

Query: 776  YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833
            +PKP    WA P  V++ G+ VT  C    +   + L+K+GS     DR+      + A 
Sbjct: 26   FPKPTL--WAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSP-EPLDRNNPLEPKNKAR 82

Query: 834  FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
            F I S+     G Y C YY  + WSEPSDP+E+V+T  Y KPTL A P PVV  G ++ L
Sbjct: 83   FSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            RC        F L++EG H     +  Q     G  A F +  V       ++C YY T 
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S+ S PL I  +    KP L      V+  GQ++TL C   V    ++L+KEGE 
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +Q  G     G     F +  +S ++ G+Y  CY     SS    PS+ L +L+ G +
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119
                SL AQPGP VA GEN+TL CQ      TF+L KEGA  P  + R       Y+A+F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
             M  V    +G Y C     S P   S+ S+ LE+ V+
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVS 419



 Score =  166 bits (420), Expect = 1e-40
 Identities = 127/396 (32%), Positives = 188/396 (47%), Gaps = 24/396 (6%)

Query: 872  YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929
            +PKPTL A+PG V+  G  V + CQG+ +   + L +EG+  PL   +     N A F +
Sbjct: 26   FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85

Query: 930  HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
             ++    +G Y C YY    S   S  S PL + +T  + KP L A PS VV  G N+TL
Sbjct: 86   PSMTEHHAGRYRCHYYS---SAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 990  WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044
             C        ++L KEGE         Q   S      FP+  ++ +   R++C Y+   
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103
            T  +   PS+ LE+L +G+  KPSLL   GP++APG+++TLQC  ++  + FVL KEG  
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160
               Q P +Q +    +A+F +  V   + G Y C Y   +     S  SD L I +  + 
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211
                SLSA P      G+++TL C+       F+L  +G   P               +F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247
             ++ V     G Y C     + P + S PS+PLELV
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELV 417



 Score =  156 bits (394), Expect = 1e-37
 Identities = 103/297 (34%), Positives = 145/297 (48%), Gaps = 19/297 (6%)

Query: 968  FPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWG--STSNDGAFPI 1025
            FPKP L+AEP SV+  G  VT+WC+G      Y LHKEG    +         N   F I
Sbjct: 26   FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85

Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085
             +++    GRY C Y+   +S+   +PS+ LE+++TG   KP+L A P P+VA G NMTL
Sbjct: 86   PSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 1086 QCQGELPDSTFVLLKEGAQE-----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140
            +C  +     FVL+KEG  +       +Q    G++A F +  V       ++C YY  +
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199
            TP+  S+ SD LEI  +    KPSL      +   G+ +TLQC   +    FVL  +GE 
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249
                   + PQ      +F +  V     G Y C Y        WS PSDPL ++ A
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMA 318



 Score =  139 bits (351), Expect = 1e-32
 Identities = 110/396 (27%), Positives = 180/396 (45%), Gaps = 28/396 (7%)

Query: 20  LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76
           L C+ +SLG  + V     P+P LW E     +    +T+WC+  S+ + ++ L K+ + 
Sbjct: 8   LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRLHKEGSP 66

Query: 77  MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134
               R  P     +  F I ++TE +AG YRC Y+   GWS+PS  LE+   G   KP  
Sbjct: 67  EPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTL 126

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184
                     G N+ + C        F+L KEG     ++Q+P           G  A+F
Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSRGFQALF 181

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            +  +TP     + C  +    P +WS PS+PL+++ +G+  KP+L    GP++APG+SL
Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241

Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300
            L+C   +    F L +  +   L++     +   ++ANF    +   + G Y C+  ++
Sbjct: 242 TLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHN 301

Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359
            S   S  SD L I +    +    L A+P   V  G+NV+L C+         L K+G 
Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGA 361

Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393
             P   L +   +      F ++ VT +  G Y C+
Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397



 Score =  136 bits (342), Expect = 2e-31
 Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 54/455 (11%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184
           G  PKP  W +  +    G  V I C G  +   + L KEG  EP+D   P      A F
Sbjct: 24  GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
           SI ++T    G Y C  +       WSEPS+PL++V+ G Y KPTL+A P P++A G ++
Sbjct: 84  SIPSMTEHHAGRYRCHYYSS---AGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140

Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298
            LRC        F LM+  +      L+    H +    +A F    +       + C+Y
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGF--QALFPVGPVTPSHRWRFTCYY 198

Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
           Y  +  +  S  SD L+I  +    K  LL     V+  GQ+++L+C   V      LYK
Sbjct: 199 YYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYK 258

Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           +GE     +P Q   A     N  F L  V+ S+ G Y C+      +    PS     L
Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNIL 316

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458
           M        SLSA P      G+ +TL C+               +HP L        R 
Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRL------RS 370

Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM------------- 505
            +       +F +S V     GTY C     ++P++ SH SEPL+L+             
Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPT 430

Query: 506 GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540
           GP         L   I +S+   L+  LL+ L +R
Sbjct: 431 GPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 67/197 (34%), Positives = 98/197 (49%), Gaps = 14/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G  PKP+L A+PG +++ G  +T+ CQG      + L KEG+ EPL++  P     +A F
Sbjct: 24   GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++    +G Y C YY  +     S  SD LE+ +T    KP+LSA PS +   G ++
Sbjct: 84   SIPSMTEHHAGRYRCHYYSSA---GWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140

Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230
            TL+C        FVL  +GE         QQ    G    F +  V       ++C Y  
Sbjct: 141  TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYY 200

Query: 1231 QAYPDIWSEPSDPLELV 1247
               P +WS PSDPLE++
Sbjct: 201  TNTPWVWSHPSDPLEIL 217



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 64/196 (32%), Positives = 87/196 (44%), Gaps = 15/196 (7%)

Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQV----RAAFP 646
           KP L       LAP ++LTL C S  G  + FVL K+G      RP  +      +A F 
Sbjct: 224 KPSLLTLQGPVLAPGQSLTLQCGSDVGYNR-FVLYKEGERDFLQRPGQQPQAGLSQANFT 282

Query: 647 LGALTQSHTGSYHCHSWEEMAV--SEPSEALE-LVGTDILPKPVISASP---TIRGQELQ 700
           LG ++ S+ G Y C+    ++   S PS+ L  L+   I     +SA P      G+ + 
Sbjct: 283 LGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVT 342

Query: 701 LRCKGWLAGMGFALYKEGEQEPVQQL----GAVGREAFFTIQRMEDKDEGNYSCRTHTEK 756
           L C+ W     F L KEG   P  +L    GA   +A F +  +     G Y C      
Sbjct: 343 LLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSS 402

Query: 757 RPFKWSEPSEPLELVI 772
            P   S PSEPLELV+
Sbjct: 403 NPHLLSHPSEPLELVV 418


>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 2 [Homo sapiens]
          Length = 631

 Score =  200 bits (508), Expect = 9e-51
 Identities = 139/416 (33%), Positives = 204/416 (49%), Gaps = 32/416 (7%)

Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624
           +TALLC GL  G     T +   P PKP LWAE    ++    +T+WC+  S   +E+ L
Sbjct: 5   LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRL 60

Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682
            K+G+     R  P   + +A F + ++T+ H G Y CH +     SEPS+ LE+V T  
Sbjct: 61  HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734
             KP +SA P+     G  + LRC        F L KEGE +       QQL + G +A 
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F +  +       ++C  +    P+ WS PS+PLE++   +  KP   T   PV+ PG  
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851
           +T  C +   +  F+LYK+G  +           G S A+F +  V   +GG Y C   +
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300

Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910
              S WS PSDP+ +++  + Y   +L AQPGP V  G++V L CQ  +Q   F L +EG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360

Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962
            AH PL+ RS+ G     A+F +  V +  +G Y C          GSY S P ++
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY---------GSYSSNPHLL 407



 Score =  182 bits (463), Expect = 1e-45
 Identities = 140/398 (35%), Positives = 191/398 (47%), Gaps = 20/398 (5%)

Query: 776  YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833
            +PKP    WA P  V++ G+ VT  C    +   + L+K+GS     DR+      + A 
Sbjct: 26   FPKPTL--WAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSP-EPLDRNNPLEPKNKAR 82

Query: 834  FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
            F I S+     G Y C YY  + WSEPSDP+E+V+T  Y KPTL A P PVV  G ++ L
Sbjct: 83   FSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            RC        F L++EG H     +  Q     G  A F +  V       ++C YY T 
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S+ S PL I  +    KP L      V+  GQ++TL C   V    ++L+KEGE 
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +Q  G     G     F +  +S ++ G+Y  CY     SS    PS+ L +L+ G +
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119
                SL AQPGP VA GEN+TL CQ      TF+L KEGA  P  + R       Y+A+F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
             M  V    +G Y C     S P   S+ S+ LE+ V+
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVS 419



 Score =  166 bits (420), Expect = 1e-40
 Identities = 127/396 (32%), Positives = 188/396 (47%), Gaps = 24/396 (6%)

Query: 872  YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929
            +PKPTL A+PG V+  G  V + CQG+ +   + L +EG+  PL   +     N A F +
Sbjct: 26   FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85

Query: 930  HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
             ++    +G Y C YY    S   S  S PL + +T  + KP L A PS VV  G N+TL
Sbjct: 86   PSMTEHHAGRYRCHYYS---SAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 990  WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044
             C        ++L KEGE         Q   S      FP+  ++ +   R++C Y+   
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103
            T  +   PS+ LE+L +G+  KPSLL   GP++APG+++TLQC  ++  + FVL KEG  
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160
               Q P +Q +    +A+F +  V   + G Y C Y   +     S  SD L I +  + 
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211
                SLSA P      G+++TL C+       F+L  +G   P               +F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247
             ++ V     G Y C     + P + S PS+PLELV
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELV 417



 Score =  156 bits (394), Expect = 1e-37
 Identities = 103/297 (34%), Positives = 145/297 (48%), Gaps = 19/297 (6%)

Query: 968  FPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWG--STSNDGAFPI 1025
            FPKP L+AEP SV+  G  VT+WC+G      Y LHKEG    +         N   F I
Sbjct: 26   FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85

Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085
             +++    GRY C Y+   +S+   +PS+ LE+++TG   KP+L A P P+VA G NMTL
Sbjct: 86   PSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142

Query: 1086 QCQGELPDSTFVLLKEGAQE-----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140
            +C  +     FVL+KEG  +       +Q    G++A F +  V       ++C YY  +
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199
            TP+  S+ SD LEI  +    KPSL      +   G+ +TLQC   +    FVL  +GE 
Sbjct: 203  TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262

Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249
                   + PQ      +F +  V     G Y C Y        WS PSDPL ++ A
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMA 318



 Score =  139 bits (351), Expect = 1e-32
 Identities = 110/396 (27%), Positives = 180/396 (45%), Gaps = 28/396 (7%)

Query: 20  LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76
           L C+ +SLG  + V     P+P LW E     +    +T+WC+  S+ + ++ L K+ + 
Sbjct: 8   LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRLHKEGSP 66

Query: 77  MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134
               R  P     +  F I ++TE +AG YRC Y+   GWS+PS  LE+   G   KP  
Sbjct: 67  EPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTL 126

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184
                     G N+ + C        F+L KEG     ++Q+P           G  A+F
Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSRGFQALF 181

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            +  +TP     + C  +    P +WS PS+PL+++ +G+  KP+L    GP++APG+SL
Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241

Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300
            L+C   +    F L +  +   L++     +   ++ANF    +   + G Y C+  ++
Sbjct: 242 TLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHN 301

Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359
            S   S  SD L I +    +    L A+P   V  G+NV+L C+         L K+G 
Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGA 361

Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393
             P   L +   +      F ++ VT +  G Y C+
Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397



 Score =  136 bits (342), Expect = 2e-31
 Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 54/455 (11%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184
           G  PKP  W +  +    G  V I C G  +   + L KEG  EP+D   P      A F
Sbjct: 24  GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
           SI ++T    G Y C  +       WSEPS+PL++V+ G Y KPTL+A P P++A G ++
Sbjct: 84  SIPSMTEHHAGRYRCHYYSS---AGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140

Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298
            LRC        F LM+  +      L+    H +    +A F    +       + C+Y
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGF--QALFPVGPVTPSHRWRFTCYY 198

Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
           Y  +  +  S  SD L+I  +    K  LL     V+  GQ+++L+C   V      LYK
Sbjct: 199 YYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYK 258

Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           +GE     +P Q   A     N  F L  V+ S+ G Y C+      +    PS     L
Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNIL 316

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458
           M        SLSA P      G+ +TL C+               +HP L        R 
Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRL------RS 370

Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM------------- 505
            +       +F +S V     GTY C     ++P++ SH SEPL+L+             
Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPT 430

Query: 506 GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540
           GP         L   I +S+   L+  LL+ L +R
Sbjct: 431 GPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 67/197 (34%), Positives = 98/197 (49%), Gaps = 14/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G  PKP+L A+PG +++ G  +T+ CQG      + L KEG+ EPL++  P     +A F
Sbjct: 24   GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++    +G Y C YY  +     S  SD LE+ +T    KP+LSA PS +   G ++
Sbjct: 84   SIPSMTEHHAGRYRCHYYSSA---GWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140

Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230
            TL+C        FVL  +GE         QQ    G    F +  V       ++C Y  
Sbjct: 141  TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYY 200

Query: 1231 QAYPDIWSEPSDPLELV 1247
               P +WS PSDPLE++
Sbjct: 201  TNTPWVWSHPSDPLEIL 217



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 64/196 (32%), Positives = 87/196 (44%), Gaps = 15/196 (7%)

Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQV----RAAFP 646
           KP L       LAP ++LTL C S  G  + FVL K+G      RP  +      +A F 
Sbjct: 224 KPSLLTLQGPVLAPGQSLTLQCGSDVGYNR-FVLYKEGERDFLQRPGQQPQAGLSQANFT 282

Query: 647 LGALTQSHTGSYHCHSWEEMAV--SEPSEALE-LVGTDILPKPVISASP---TIRGQELQ 700
           LG ++ S+ G Y C+    ++   S PS+ L  L+   I     +SA P      G+ + 
Sbjct: 283 LGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVT 342

Query: 701 LRCKGWLAGMGFALYKEGEQEPVQQL----GAVGREAFFTIQRMEDKDEGNYSCRTHTEK 756
           L C+ W     F L KEG   P  +L    GA   +A F +  +     G Y C      
Sbjct: 343 LLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSS 402

Query: 757 RPFKWSEPSEPLELVI 772
            P   S PSEPLELV+
Sbjct: 403 NPHLLSHPSEPLELVV 418


>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
           member 6 [Homo sapiens]
          Length = 481

 Score =  196 bits (498), Expect = 1e-49
 Identities = 140/419 (33%), Positives = 204/419 (48%), Gaps = 23/419 (5%)

Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624
           +TALLC GL  G     T +   P PKP LWAE    ++    +T+WC+  S   +E+ L
Sbjct: 5   LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SLEAQEYQL 60

Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682
            K+G+     R  P   + +A F + ++TQ H G Y CH +     SEPS+ LELV T  
Sbjct: 61  DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734
             KP +SA P+     G  + LRC        F L KEGE +       QQL + G +A 
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F +  +       ++C  +    P  WS PS+PLE++   +  KP   T   PV+ PG  
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851
           +T  C +   +  F+LYK+G  +           G S A+F +  V    GG Y C   +
Sbjct: 241 LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH 300

Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910
              S WS PSDP+ +++  + Y   +L AQPGP V  G++V L CQ       F L +EG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEG 360

Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965
            AH PL+ RS+ G     A+F +  V +  +G Y C    ++  +  S+ S PL + V+
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVS 419



 Score =  187 bits (475), Expect = 6e-47
 Identities = 150/425 (35%), Positives = 200/425 (47%), Gaps = 22/425 (5%)

Query: 776  YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833
            +PKP    WA P  V++ G+ VT  C    +   + L K+GS     DR+      + A 
Sbjct: 26   FPKPTL--WAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSP-EPLDRNNPLEPKNKAR 82

Query: 834  FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
            F I S+     G Y C YY  + WSEPSDP+ELV+T FY KPTL A P PVV  G ++ L
Sbjct: 83   FSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTL 142

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            RC        F L++EG H     +  Q     G  A F +  V       ++C YY T 
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S+ S PL I  +    KP L      V+  GQ++TL C   V    ++L+KEGE 
Sbjct: 203  TPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGER 262

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +Q  G     G     F +  +S +  G+Y  CY     SS    PS+ L +L+ G +
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119
                SL AQPGP VA GEN+TL CQ      TF+L KEGA  P  + R       Y+A+F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSL--SAWPSTMFKLGK 1177
             M  V    +G Y C     S P   S  S+ LE+ V+      SL  +  PST     K
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAK 441

Query: 1178 DITLQ 1182
            D T++
Sbjct: 442  DYTVE 446



 Score =  171 bits (432), Expect = 6e-42
 Identities = 138/444 (31%), Positives = 209/444 (47%), Gaps = 40/444 (9%)

Query: 872  YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929
            +PKPTL A+PG V+  G  V + CQG+ +   + L +EG+  PL   +     N A F +
Sbjct: 26   FPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARFSI 85

Query: 930  HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
             ++    +G Y C YY    S   S  S PL + +T  + KP L A PS VV  G N+TL
Sbjct: 86   PSMTQHHAGRYRCHYYS---SAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTL 142

Query: 990  WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044
             C        ++L KEGE         Q   S      FP+  ++ +   R++C Y+   
Sbjct: 143  RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTN 202

Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103
            T  +   PS+ LE+L +G+  KPSLL   GP++APG+++TLQC  ++    FVL KEG  
Sbjct: 203  TPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGER 262

Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160
               Q P +Q +    +A+F +  V     G Y C Y   +     S  SD L I +  + 
Sbjct: 263  DFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321

Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211
                SLSA P      G+++TL C+       F+L  +G   P               +F
Sbjct: 322  YDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381

Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV------GAAGPV----------AQ 1255
             ++ V     G Y C     + P + S PS+PLEL+      G++ P           A+
Sbjct: 382  PMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAK 441

Query: 1256 ECTVGNIVRSSLIVVVVVALGVVL 1279
            + TV N++R  +  +V+V LG++L
Sbjct: 442  DYTVENLIRMGMAGLVLVFLGILL 465



 Score =  136 bits (342), Expect = 2e-31
 Identities = 121/445 (27%), Positives = 195/445 (43%), Gaps = 30/445 (6%)

Query: 20  LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76
           L C+ +SLG  + V     P+P LW E     +    +T+WC+  S  + ++ L K+ + 
Sbjct: 8   LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SLEAQEYQLDKEGSP 66

Query: 77  MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134
               R  P     +  F I ++T+ +AG YRC Y+   GWS+PS  LEL   G   KP  
Sbjct: 67  EPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGFYNKPTL 126

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184
                     G N+ + C        F+L KEG     ++Q+P           G  A+F
Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSGGFQALF 181

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            +  +TP     + C  +    P +WS PS+PL+++ +G+  KP+L    GP++APG+SL
Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241

Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300
            L+C   +    F L +  +   L++     +   ++ANF    +     G Y C+  ++
Sbjct: 242 TLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHN 301

Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359
            S   S  SD L I +    +    L A+P   V  G+NV+L C+         L K+G 
Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGA 361

Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDK 417
             P   L +   +      F ++ VT +  G Y C+   +    +       +ELMV   
Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGH 421

Query: 418 PPKPSL--SAWPSTVFKLGKAITLQ 440
               SL  +  PST     K  T++
Sbjct: 422 SGGSSLPPTGPPSTPASHAKDYTVE 446



 Score =  132 bits (331), Expect = 3e-30
 Identities = 122/407 (29%), Positives = 170/407 (41%), Gaps = 41/407 (10%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184
           G  PKP  W +  +    G  V I C G L+   + L KEG  EP+D   P      A F
Sbjct: 24  GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
           SI ++T    G Y C  +       WSEPS+PL+LV+ G Y KPTL+A P P++A G ++
Sbjct: 84  SIPSMTQHHAGRYRCHYYSS---AGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNM 140

Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298
            LRC        F LM+  +      L+    H      +A F    +       + C+Y
Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGF--QALFPVGPVTPSHRWRFTCYY 198

Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
           Y  +     S  SD L+I  +    K  LL     V+  GQ+++L+C   V      LYK
Sbjct: 199 YYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYK 258

Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           +GE     +P Q   A     N  F L  V+ S  G Y C+      +    PS     L
Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPLNIL 316

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458
           M        SLSA P      G+ +TL C+               +HP L        R 
Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRL------RS 370

Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
            +       +F +S V     GTY C     ++P++ S  SEPL+LM
Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELM 417



 Score =  101 bits (252), Expect = 4e-21
 Identities = 68/197 (34%), Positives = 99/197 (50%), Gaps = 14/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G  PKP+L A+PG +++ G  +T+ CQG L    + L KEG+ EPL++  P     +A F
Sbjct: 24   GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++    +G Y C YY  +     S  SD LE+ +T    KP+LSA PS +   G ++
Sbjct: 84   SIPSMTQHHAGRYRCHYYSSA---GWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNM 140

Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230
            TL+C        FVL  +GE         QQ    G    F +  V       ++C Y  
Sbjct: 141  TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYY 200

Query: 1231 QAYPDIWSEPSDPLELV 1247
               P +WS PSDPLE++
Sbjct: 201  TNTPRVWSHPSDPLEIL 217


>gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]
          Length = 495

 Score =  184 bits (468), Expect = 4e-46
 Identities = 159/511 (31%), Positives = 236/511 (46%), Gaps = 31/511 (6%)

Query: 562  MLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKE 621
            M  +V  LL  G+  G + E    +    +P LWAE+   L P  N+TL C++    T +
Sbjct: 1    MSMLVVFLLLWGVTWGPVTEAA--IFYETQPSLWAESESLLKPLANVTLTCQAHL-ETPD 57

Query: 622  FVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTD 681
            F L K+G         S  ++  F L   TQ   G Y C S      ++ S+ LEL G  
Sbjct: 58   FQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114

Query: 682  ILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGA-VGREAFFTI 737
             LP P +S +P      G +    C+G L G+ F L +EG+ E ++   A    EA F +
Sbjct: 115  SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV 174

Query: 738  QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTW--ASPVVTPGARV 795
             +      GNYSC   T+      SEPS  + +      P P       +S V+ PG +V
Sbjct: 175  HQ-----PGNYSCSYRTDGEG-ALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKV 228

Query: 796  TFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--- 852
            T  C  P   + F L +   E+    RS  SP      F + +V +GDGG+Y+CRY    
Sbjct: 229  TLTCVAPLSGVDFQLRRGEKELL-VPRSSTSP--DRIFFHLNAVALGDGGHYTCRYRLHD 285

Query: 853  DFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-- 909
            + + WS  S PVEL+++ E  P P    +P      G+++ LRC    +G RFAL++E  
Sbjct: 286  NQNGWSGDSAPVELILSDETLPAPEFSPEPE----SGRALRLRCLAPLEGARFALVREDR 341

Query: 910  GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFP 969
            G     +F+S +G  A F LH +   DS NYSC+Y +      GS  S  L + V    P
Sbjct: 342  GGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPP 401

Query: 970  KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029
            +P L A  S  V  G++  L C GP+  V + L +EGE  +++   +        +  + 
Sbjct: 402  RPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVG 461

Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLV 1060
                G Y C Y      + + + S+ +ELLV
Sbjct: 462  PQHAGNYRCRYRSWVPHTFESELSDPVELLV 492



 Score =  152 bits (383), Expect = 3e-36
 Identities = 151/480 (31%), Positives = 209/480 (43%), Gaps = 32/480 (6%)

Query: 784  WASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGI 841
            WA    ++ P A VT  C    +   F L+K+G  +A       SP A    FL+     
Sbjct: 32   WAESESLLKPLANVTLTCQAHLETPDFQLFKNG--VAQEPVHLDSP-AIKHQFLLT---- 84

Query: 842  GDG-GNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900
            GD  G Y CR    + W++ S  +EL   +  P P L   P   + PG      C+G  +
Sbjct: 85   GDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLR 144

Query: 901  GMRFALLQEGAHVPLQFRSVSGN-SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959
            G+ F L +EG H  L+      +  A F +H       GNYSC Y  T      S  S  
Sbjct: 145  GVTFLLRREGDHEFLEVPEAQEDVEATFPVH-----QPGNYSCSY-RTDGEGALSEPSAT 198

Query: 960  LMIWVTDTFPKPWLF--AEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGST 1017
            + I      P P L    E S V+  G  VTL C  P+ GV + L + GE   +    ST
Sbjct: 199  VTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR-GEKELLVPRSST 257

Query: 1018 SNDGAFPITN-ISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-LLPKPSLLAQPGP 1075
            S D  F   N ++    G Y+C Y      +     S  +EL+++   LP P    +P  
Sbjct: 258  SPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP-- 315

Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKE--GAQEPLEQQRPSGYRADFWMPAVRGEDSGIYS 1133
                G  + L+C   L  + F L++E  G +     Q P+G  A F +  +   DS  YS
Sbjct: 316  --ESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYS 373

Query: 1134 CVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFV 1193
            CVY     PF  S  S+ LE+ V   PP+P L A  S     G+D  L+C GP+P V F 
Sbjct: 374  CVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFE 433

Query: 1194 LEHDGE-EAPQQFSEDG---DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249
            L  +GE +A +     G   +  +  V  +  GNY C YR        SE SDP+EL+ A
Sbjct: 434  LLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVA 493



 Score =  141 bits (356), Expect = 4e-33
 Identities = 132/469 (28%), Positives = 196/469 (41%), Gaps = 32/469 (6%)

Query: 701  LRCKGWLAGMGFALYKEG-EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPF 759
            L C+  L    F L+K G  QEPV       +  F     +    +G Y CR+       
Sbjct: 47   LTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFL----LTGDTQGRYRCRSGLSTG-- 100

Query: 760  KWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIAS 819
             W++ S+ LEL   +  P P+        +TPG + T  C    + ++F+L ++G     
Sbjct: 101  -WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREG----- 154

Query: 820  SDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--DFSIWSEPSDPVELVVTEFYPKPTL 877
             D  +      A   +  +  +   GNYSC Y        SEPS  V +      P P L
Sbjct: 155  -DHEFLEV-PEAQEDVEATFPVHQPGNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVL 212

Query: 878  L--AQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAE 935
            +   +   V+ PG  V L C     G+ F L +    + +   S S +   F L+ V   
Sbjct: 213  MHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALG 272

Query: 936  DSGNYSCIYYETTMSNRGSYLSMPLMIWVTD-TFPKPWLFAEPSSVVPMGQNVTLWCRGP 994
            D G+Y+C Y      N  S  S P+ + ++D T P P    EP S    G+ + L C  P
Sbjct: 273  DGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPES----GRALRLRCLAP 328

Query: 995  VHGVGYILHKE--GEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCY---HPDWTSSIK 1049
            + G  + L +E  G     +       +  F + NIS      YSC Y    P +  S  
Sbjct: 329  LEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGS-- 386

Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109
              PS  LEL V G  P+P L A     V  G +  L+C+G +PD TF LL+EG  + ++ 
Sbjct: 387  -APSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKT 445

Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158
             R  G  A+  +  V  + +G Y C Y         S  SD +E+ V +
Sbjct: 446  VRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAE 494



 Score =  136 bits (343), Expect = 1e-31
 Identities = 132/509 (25%), Positives = 201/509 (39%), Gaps = 33/509 (6%)

Query: 11  TMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLL 70
           +ML  F +L       +   +I  + QP LW ES     P  N+TL C++    +  F L
Sbjct: 2   SMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLE-TPDFQL 60

Query: 71  LKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLP 130
            K+      +       +  FL   LT    G YRC     TGW++ SK+LEL  P  LP
Sbjct: 61  FKNGVAQEPVHLDSPAIKHQFL---LTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLP 117

Query: 131 KPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-QVPTGTMAIFSIDNL 189
            P   +   +   PG     +C G L+ + F+L +EG  E ++  +      A F +   
Sbjct: 118 APWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV--- 174

Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAH--PGPIMAPGESLNLR 247
                G Y C         L SEPS  + +      P P L  H     ++ PG  + L 
Sbjct: 175 --HQPGNYSCSYRTDGEGAL-SEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLT 231

Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSL 307
           C  P+ G+ F L R E  E       T  +   F   ++ + D GHY C Y         
Sbjct: 232 CVAPLSGVDFQLRRGEK-ELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRY--------R 282

Query: 308 LSDVLKIWVTDTFPKTWLLARP-------SAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360
           L D    W  D+ P   +L+         S   + G+ + LRC  P++G   AL ++   
Sbjct: 283 LHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRG 342

Query: 361 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420
                   +       F L+N++ +D+  YSC Y+              +EL V   PP+
Sbjct: 343 GRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPR 402

Query: 421 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL----EWEERETFQKFSVNGDFIISNVDG 476
           P L A  S     G+   L+C    P + F L    E +  +T +      +  +  V  
Sbjct: 403 PQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGP 462

Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
           +  G Y C YR        S  S+P++L+
Sbjct: 463 QHAGNYRCRYRSWVPHTFESELSDPVELL 491



 Score =  121 bits (304), Expect = 4e-27
 Identities = 103/358 (28%), Positives = 157/358 (43%), Gaps = 22/358 (6%)

Query: 622 FVLLKDGTGWIATRP-ASEQVRAAFPLGALTQSHTGSYHC--HSWEEMAVSEPSEALELV 678
           F+L ++G       P A E V A FP+        G+Y C   +  E A+SEPS  + + 
Sbjct: 148 FLLRREGDHEFLEVPEAQEDVEATFPV-----HQPGNYSCSYRTDGEGALSEPSATVTIE 202

Query: 679 GTDILPKPVI-----SASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREA 733
                P PV+     S+     G ++ L C   L+G+ F L +  ++  V +        
Sbjct: 203 ELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRI 262

Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIK-EMYPKPFFKTWASPVVTPG 792
           FF +  +   D G+Y+CR         WS  S P+EL++  E  P P F    SP    G
Sbjct: 263 FFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEF----SPEPESG 318

Query: 793 ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852
             +   C  P +   F L ++        R + SP  + A F + ++ + D  NYSC Y 
Sbjct: 319 RALRLRCLAPLEGARFALVREDRGGRRVHR-FQSPAGTEALFELHNISVADSANYSCVYV 377

Query: 853 DFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909
           D       S PS+ +EL V    P+P L A     V  G+  +LRC+G    + F LL+E
Sbjct: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437

Query: 910 GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDT 967
           G    ++     G +A+  L  VG + +GNY C Y         S LS P+ + V ++
Sbjct: 438 GETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAES 495



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 61/188 (32%), Positives = 83/188 (44%), Gaps = 9/188 (4%)

Query: 1066 KPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG-AQEPLEQQRPSGYRADFWMPAV 1124
            +PSL A+   ++ P  N+TL CQ  L    F L K G AQEP+    P+  +  F    +
Sbjct: 28   QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSPA-IKHQF---LL 83

Query: 1125 RGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCR 1184
             G+  G Y C   L +     +  S  LE+      P P LS  P +    G   T  CR
Sbjct: 84   TGDTQGRYRCRSGLST---GWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCR 140

Query: 1185 GPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPL 1244
            G L GV F+L  +G+    +  E  + V         GNYSCSYR      + SEPS  +
Sbjct: 141  GVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNYSCSYRTDGEGAL-SEPSATV 199

Query: 1245 ELVGAAGP 1252
             +   A P
Sbjct: 200  TIEELAAP 207



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 3/135 (2%)

Query: 91  FLIGALTESNAGLYRCCYWK---ETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCN 147
           F +  ++ +++  Y C Y       G S PS+ LEL   G  P+P          L G +
Sbjct: 359 FELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRD 418

Query: 148 VNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLP 207
             + C G + D+ F L +EG  + V      G  A   +  + P+  G Y CR    +  
Sbjct: 419 AVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPH 478

Query: 208 TLWSEPSNPLKLVVA 222
           T  SE S+P++L+VA
Sbjct: 479 TFESELSDPVELLVA 493


>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
            member 5 isoform 1 [Homo sapiens]
          Length = 591

 Score =  182 bits (461), Expect = 2e-45
 Identities = 146/421 (34%), Positives = 194/421 (46%), Gaps = 27/421 (6%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+  G  VT  C  P +   + L K+G   A   ++   PGA A  F
Sbjct: 27   PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83

Query: 835  LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894
             I S      G Y C Y   + WSEPSDP+ELV T FY +PTLLA P PVV  G +V L+
Sbjct: 84   HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQ 143

Query: 895  CQGTFQGMRFALLQEGAHVPLQFRS----VSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950
            C      + F L++E   +P    S       + A F +  V       + C YY     
Sbjct: 144  CDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNP 203

Query: 951  NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS 1010
               S  S  L I V     KP L     SVV  G ++TL CR  V    ++L+KEGE   
Sbjct: 204  QVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDL 263

Query: 1011 MQLWGSTSNDGA----FPITNISGTSMGRYSCC----YHPDWTSSIKIQPSNTLELLVTG 1062
            +Q  G     G     F +  +S +  G+Y C       P W++     PS+ L++L+ G
Sbjct: 264  VQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSA-----PSDPLDILIAG 318

Query: 1063 LLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRA 1117
            L+P  P+L  QPGP VA GEN+TL CQ      TF L KEGA  P      + +   ++A
Sbjct: 319  LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378

Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGK 1177
            +F M  V     G Y C   + S P+  S+ S   E+ V+     PSLS   ST    G 
Sbjct: 379  EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGP 438

Query: 1178 D 1178
            +
Sbjct: 439  E 439



 Score =  164 bits (414), Expect = 7e-40
 Identities = 138/460 (30%), Positives = 203/460 (44%), Gaps = 27/460 (5%)

Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620
           M   ++ L+C GL  G     T +   T PKP LWAE    +A  K +TLWC+ P   T+
Sbjct: 1   MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56

Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678
           E+ L K+G  W   R  P     +A F + +      G Y C+       SEPS+ LELV
Sbjct: 57  EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 679 GTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP----VQQLGAVGR 731
            T    +P + A P+     G  + L+C      + F L +E ++ P     Q+L     
Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176

Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTP 791
           +A F +  +       + C  +  K P  WS PS+ LE+++  +  KP        VV  
Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236

Query: 792 GARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850
           G  +T  C +   +  F+LYK+G  ++          G S A+F +  V    GG Y C 
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295

Query: 851 YYDFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906
           Y   ++   WS PSDP+++++    P  P L  QPGP V  G++V L CQ   Q   F L
Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355

Query: 907 LQEG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962
            +EG AH PL  +S      + A+F +  V +   G Y C     +     S  S P  +
Sbjct: 356 TKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQEL 415

Query: 963 WVTDTFPKPWLFAEPSSVVPMG---QNVTLWCRGPVHGVG 999
            V+     P L    S+  P G   Q +T     P  G+G
Sbjct: 416 VVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLG 455



 Score =  152 bits (385), Expect = 2e-36
 Identities = 128/403 (31%), Positives = 189/403 (46%), Gaps = 32/403 (7%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926
            PKPTL A+P  V+  GK V L CQG  +   + L +EG         PL+     G  A 
Sbjct: 27   PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + +   + +G Y C YYET      S  S PL +  T  + +P L A PS VV  G N
Sbjct: 83   FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGFYAEPTLLALPSPVVASGGN 139

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHP 1042
            VTL C      + ++L +E +     L+      G     FP+  ++ +   R+ C Y+ 
Sbjct: 140  VTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYY 199

Query: 1043 DWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG 1102
                 +   PS+ LE+LV G+  KPSLL   G +VA G ++TLQC+ ++    FVL KEG
Sbjct: 200  RKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEG 259

Query: 1103 AQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158
              + ++   QQ  +G  +A+F +  V     G Y C    + +P   S  SD L+I +  
Sbjct: 260  EHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 318

Query: 1159 KPPK-PSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDG 1209
              P  P+LS  P      G+++TL C+       F L  +G   P        Q +    
Sbjct: 319  LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378

Query: 1210 DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
            +F ++ V     G Y C   +++YP + S PS P ELV  +GP
Sbjct: 379  EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSGP 420



 Score =  144 bits (364), Expect = 4e-34
 Identities = 109/295 (36%), Positives = 142/295 (48%), Gaps = 18/295 (6%)

Query: 967  TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG--EATSMQLWGSTSNDGAFP 1024
            T PKP L+AEP+SV+  G+ VTLWC+GP+    Y L KEG   A   Q          F 
Sbjct: 25   TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84

Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084
            I +    S GRY C Y    T +   +PS+ LEL+ TG   +P+LLA P P+VA G N+T
Sbjct: 85   IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVT 141

Query: 1085 LQCQGELPDSTFVLLKEGAQEP---LEQQRPSG-YRADFWMPAVRGEDSGIYSCVYYLDS 1140
            LQC       TFVL++E  + P     Q+ P G  +A F +  V       + C YY   
Sbjct: 142  LQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRK 201

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199
             P   SN SD LEI V     KPSL     ++   G  +TLQCR  +    FVL  +GE 
Sbjct: 202  NPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH 261

Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247
                   + PQ      +F +  V     G Y C Y        WS PSDPL+++
Sbjct: 262  DLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDIL 315



 Score =  142 bits (359), Expect = 2e-33
 Identities = 129/409 (31%), Positives = 177/409 (43%), Gaps = 30/409 (7%)

Query: 683  LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733
            LPKP + A P     RG+ + L C+G L    + L KEG       Q P++     G +A
Sbjct: 26   LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81

Query: 734  FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793
             F I        G Y C   T   P  WSEPS+PLELV    Y +P      SPVV  G 
Sbjct: 82   KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGG 138

Query: 794  RVTFNCSTPHQHMSFILYKDGSEIASSDRSWASP-GASAAHFLIISVGIGDGGNYSCRYY 852
             VT  C T    ++F+L ++  ++  +  S   P G S A F +  V       + C YY
Sbjct: 139  NVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY 198

Query: 853  ---DFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909
               +  +WS PSD +E++V     KP+LL   G VV  G S+ L+C+       F L +E
Sbjct: 199  YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKE 258

Query: 910  GAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965
            G H  +Q          + A+F L  V     G Y C Y    +S R S  S PL I + 
Sbjct: 259  GEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILIA 317

Query: 966  DTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA----TSMQLWGSTSND 1020
               P  P L  +P   V  G+NVTL C+       + L KEG A         + S  + 
Sbjct: 318  GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377

Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSL 1069
              F ++ ++    G Y C         +   PS   EL+V+G    PSL
Sbjct: 378  AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSL 426



 Score =  138 bits (347), Expect = 4e-32
 Identities = 126/437 (28%), Positives = 195/437 (44%), Gaps = 24/437 (5%)

Query: 12  MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68
           M  T +VL+ C+ +S+G  + V     P+P LW E     A  + +TLWC+ P       
Sbjct: 1   MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59

Query: 69  LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124
           L   DK  + W R    P     +  F I +    +AG YRC Y    GWS+PS  LEL 
Sbjct: 60  L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEP---VDYQVPTG-T 180
           A G   +P            G NV + C      L F+L +E    P      ++P G +
Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176

Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240
            A+F +  +TP     + C  + +  P +WS PS+ L+++V G+  KP+L    G ++A 
Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236

Query: 241 GESLNLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297
           G SL L+C+  +    F L +  +   ++ S    +   ++ANF    +     G Y C+
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296

Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLA-RPSAVVQMGQNVSLRCRGPVDGVGLALY 355
             ++ S R S  SD L I +    P    L+ +P   V  G+NV+L C+         L 
Sbjct: 297 GAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLT 356

Query: 356 KKGEDKPLQFLDA--TSIDDNTSFFLNNVTYSDTGIYSCHYLL-TWKTSIRMPSHNTVEL 412
           K+G   P   L +   S      F ++ VT +  G Y C+  + ++   +  PS+   EL
Sbjct: 357 KEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY-PQEL 415

Query: 413 MVVDKPPKPSLSAWPST 429
           +V      PSLS   ST
Sbjct: 416 VVSGPSGDPSLSPTGST 432



 Score =  137 bits (344), Expect = 9e-32
 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 28/405 (6%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIF 184
           G LPKP  W +  +    G  V + C G L+   + L KEG  +A      +  G  A F
Sbjct: 24  GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I +   +  G Y C       P  WSEPS+PL+LV  G Y +PTL A P P++A G ++
Sbjct: 84  HIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140

Query: 245 NLRCQGPIYGMTFALMRVED-LEKSFYHKKTIKNEANFFFQSLKIQDT--GHYLCFYYDA 301
            L+C      +TF L+  E  L ++ Y +K  K  +   F    +  +    + C+YY  
Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY-- 198

Query: 302 SYR-----GSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
            YR      S  SD+L+I V     K  LL    +VV  G +++L+CR  V      LYK
Sbjct: 199 -YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257

Query: 357 KGEDKPLQ--FLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           +GE   +Q       +     +F L  V+ S  G Y C+           PS     L+ 
Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIA 317

Query: 415 VDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVN 466
              P  P+LS  P      G+ +TL C+  H +  F L  E         +  +Q +   
Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377

Query: 467 GDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
            +F +S V     GTY C   + ++P + S  S P +L+  GP+G
Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 422



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 13/196 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G LPKP+L A+P  ++A G+ +TL CQG L    + L KEG     ++Q P   G +A F
Sbjct: 24   GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P+   + +G Y C Y    TP   S  SD LE+  T    +P+L A PS +   G ++
Sbjct: 84   HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140

Query: 1180 TLQCRGPLPGVEFVLEHDGEEAPQQF--------SEDGDFVINNVEGKGIGNYSCSYRLQ 1231
            TLQC      + FVL  + ++ P+               F +  V       + C Y  +
Sbjct: 141  TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYR 200

Query: 1232 AYPDIWSEPSDPLELV 1247
              P +WS PSD LE++
Sbjct: 201  KNPQVWSNPSDLLEIL 216


>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
            member 5 isoform 2 [Homo sapiens]
          Length = 590

 Score =  181 bits (460), Expect = 3e-45
 Identities = 145/414 (35%), Positives = 192/414 (46%), Gaps = 27/414 (6%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+  G  VT  C  P +   + L K+G   A   ++   PGA A  F
Sbjct: 27   PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83

Query: 835  LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894
             I S      G Y C Y   + WSEPSDP+ELV T FY +PTLLA P PVV  G +V L+
Sbjct: 84   HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQ 143

Query: 895  CQGTFQGMRFALLQEGAHVPLQFRS----VSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950
            C      + F L++E   +P    S       + A F +  V       + C YY     
Sbjct: 144  CDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNP 203

Query: 951  NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS 1010
               S  S  L I V     KP L     SVV  G ++TL CR  V    ++L+KEGE   
Sbjct: 204  QVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDL 263

Query: 1011 MQLWGSTSNDGA----FPITNISGTSMGRYSCC----YHPDWTSSIKIQPSNTLELLVTG 1062
            +Q  G     G     F +  +S +  G+Y C       P W++     PS+ L++L+ G
Sbjct: 264  VQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSA-----PSDPLDILIAG 318

Query: 1063 LLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRA 1117
            L+P  P+L  QPGP VA GEN+TL CQ      TF L KEGA  P      + +   ++A
Sbjct: 319  LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378

Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPST 1171
            +F M  V     G Y C   + S P+  S+ S   E+ V+     PSLS   ST
Sbjct: 379  EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGST 432



 Score =  163 bits (412), Expect = 1e-39
 Identities = 124/400 (31%), Positives = 183/400 (45%), Gaps = 24/400 (6%)

Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620
           M   ++ L+C GL  G     T +   T PKP LWAE    +A  K +TLWC+ P   T+
Sbjct: 1   MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56

Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678
           E+ L K+G  W   R  P     +A F + +      G Y C+       SEPS+ LELV
Sbjct: 57  EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 679 GTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP----VQQLGAVGR 731
            T    +P + A P+     G  + L+C      + F L +E ++ P     Q+L     
Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176

Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTP 791
           +A F +  +       + C  +  K P  WS PS+ LE+++  +  KP        VV  
Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236

Query: 792 GARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850
           G  +T  C +   +  F+LYK+G  ++          G S A+F +  V    GG Y C 
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295

Query: 851 YYDFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906
           Y   ++   WS PSDP+++++    P  P L  QPGP V  G++V L CQ   Q   F L
Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355

Query: 907 LQEG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSC 942
            +EG AH PL  +S      + A+F +  V +   G Y C
Sbjct: 356 TKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRC 395



 Score =  152 bits (385), Expect = 2e-36
 Identities = 128/403 (31%), Positives = 189/403 (46%), Gaps = 32/403 (7%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926
            PKPTL A+P  V+  GK V L CQG  +   + L +EG         PL+     G  A 
Sbjct: 27   PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + +   + +G Y C YYET      S  S PL +  T  + +P L A PS VV  G N
Sbjct: 83   FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGFYAEPTLLALPSPVVASGGN 139

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHP 1042
            VTL C      + ++L +E +     L+      G     FP+  ++ +   R+ C Y+ 
Sbjct: 140  VTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYY 199

Query: 1043 DWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG 1102
                 +   PS+ LE+LV G+  KPSLL   G +VA G ++TLQC+ ++    FVL KEG
Sbjct: 200  RKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEG 259

Query: 1103 AQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158
              + ++   QQ  +G  +A+F +  V     G Y C    + +P   S  SD L+I +  
Sbjct: 260  EHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 318

Query: 1159 KPPK-PSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDG 1209
              P  P+LS  P      G+++TL C+       F L  +G   P        Q +    
Sbjct: 319  LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378

Query: 1210 DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
            +F ++ V     G Y C   +++YP + S PS P ELV  +GP
Sbjct: 379  EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSGP 420



 Score =  144 bits (364), Expect = 4e-34
 Identities = 109/295 (36%), Positives = 142/295 (48%), Gaps = 18/295 (6%)

Query: 967  TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG--EATSMQLWGSTSNDGAFP 1024
            T PKP L+AEP+SV+  G+ VTLWC+GP+    Y L KEG   A   Q          F 
Sbjct: 25   TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84

Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084
            I +    S GRY C Y    T +   +PS+ LEL+ TG   +P+LLA P P+VA G N+T
Sbjct: 85   IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVT 141

Query: 1085 LQCQGELPDSTFVLLKEGAQEP---LEQQRPSG-YRADFWMPAVRGEDSGIYSCVYYLDS 1140
            LQC       TFVL++E  + P     Q+ P G  +A F +  V       + C YY   
Sbjct: 142  LQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRK 201

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199
             P   SN SD LEI V     KPSL     ++   G  +TLQCR  +    FVL  +GE 
Sbjct: 202  NPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH 261

Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247
                   + PQ      +F +  V     G Y C Y        WS PSDPL+++
Sbjct: 262  DLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDIL 315



 Score =  144 bits (363), Expect = 6e-34
 Identities = 137/435 (31%), Positives = 187/435 (42%), Gaps = 32/435 (7%)

Query: 683  LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733
            LPKP + A P     RG+ + L C+G L    + L KEG       Q P++     G +A
Sbjct: 26   LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81

Query: 734  FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793
             F I        G Y C   T   P  WSEPS+PLELV    Y +P      SPVV  G 
Sbjct: 82   KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGG 138

Query: 794  RVTFNCSTPHQHMSFILYKDGSEIASSDRSWASP-GASAAHFLIISVGIGDGGNYSCRYY 852
             VT  C T    ++F+L ++  ++  +  S   P G S A F +  V       + C YY
Sbjct: 139  NVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY 198

Query: 853  ---DFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909
               +  +WS PSD +E++V     KP+LL   G VV  G S+ L+C+       F L +E
Sbjct: 199  YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKE 258

Query: 910  GAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965
            G H  +Q          + A+F L  V     G Y C Y    +S R S  S PL I + 
Sbjct: 259  GEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILIA 317

Query: 966  DTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA----TSMQLWGSTSND 1020
               P  P L  +P   V  G+NVTL C+       + L KEG A         + S  + 
Sbjct: 318  GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377

Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080
              F ++ ++    G Y C         +   PS   EL+V+G    PS L+  G    PG
Sbjct: 378  AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPS-LSPTGSTPTPG 436

Query: 1081 -ENMTLQCQGELPDS 1094
             E+  L   G  P S
Sbjct: 437  PEDQPLTPTGLDPQS 451



 Score =  138 bits (347), Expect = 4e-32
 Identities = 126/437 (28%), Positives = 195/437 (44%), Gaps = 24/437 (5%)

Query: 12  MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68
           M  T +VL+ C+ +S+G  + V     P+P LW E     A  + +TLWC+ P       
Sbjct: 1   MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59

Query: 69  LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124
           L   DK  + W R    P     +  F I +    +AG YRC Y    GWS+PS  LEL 
Sbjct: 60  L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEP---VDYQVPTG-T 180
           A G   +P            G NV + C      L F+L +E    P      ++P G +
Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176

Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240
            A+F +  +TP     + C  + +  P +WS PS+ L+++V G+  KP+L    G ++A 
Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236

Query: 241 GESLNLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297
           G SL L+C+  +    F L +  +   ++ S    +   ++ANF    +     G Y C+
Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296

Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLA-RPSAVVQMGQNVSLRCRGPVDGVGLALY 355
             ++ S R S  SD L I +    P    L+ +P   V  G+NV+L C+         L 
Sbjct: 297 GAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLT 356

Query: 356 KKGEDKPLQFLDA--TSIDDNTSFFLNNVTYSDTGIYSCHYLL-TWKTSIRMPSHNTVEL 412
           K+G   P   L +   S      F ++ VT +  G Y C+  + ++   +  PS+   EL
Sbjct: 357 KEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY-PQEL 415

Query: 413 MVVDKPPKPSLSAWPST 429
           +V      PSLS   ST
Sbjct: 416 VVSGPSGDPSLSPTGST 432



 Score =  137 bits (344), Expect = 9e-32
 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 28/405 (6%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIF 184
           G LPKP  W +  +    G  V + C G L+   + L KEG  +A      +  G  A F
Sbjct: 24  GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I +   +  G Y C       P  WSEPS+PL+LV  G Y +PTL A P P++A G ++
Sbjct: 84  HIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140

Query: 245 NLRCQGPIYGMTFALMRVED-LEKSFYHKKTIKNEANFFFQSLKIQDT--GHYLCFYYDA 301
            L+C      +TF L+  E  L ++ Y +K  K  +   F    +  +    + C+YY  
Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY-- 198

Query: 302 SYR-----GSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
            YR      S  SD+L+I V     K  LL    +VV  G +++L+CR  V      LYK
Sbjct: 199 -YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257

Query: 357 KGEDKPLQ--FLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           +GE   +Q       +     +F L  V+ S  G Y C+           PS     L+ 
Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIA 317

Query: 415 VDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVN 466
              P  P+LS  P      G+ +TL C+  H +  F L  E         +  +Q +   
Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377

Query: 467 GDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
            +F +S V     GTY C   + ++P + S  S P +L+  GP+G
Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 422



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 13/196 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G LPKP+L A+P  ++A G+ +TL CQG L    + L KEG     ++Q P   G +A F
Sbjct: 24   GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P+   + +G Y C Y    TP   S  SD LE+  T    +P+L A PS +   G ++
Sbjct: 84   HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140

Query: 1180 TLQCRGPLPGVEFVLEHDGEEAPQQF--------SEDGDFVINNVEGKGIGNYSCSYRLQ 1231
            TLQC      + FVL  + ++ P+               F +  V       + C Y  +
Sbjct: 141  TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYR 200

Query: 1232 AYPDIWSEPSDPLELV 1247
              P +WS PSD LE++
Sbjct: 201  KNPQVWSNPSDLLEIL 216


>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
            member 2 isoform 1 [Homo sapiens]
          Length = 598

 Score =  178 bits (451), Expect = 4e-44
 Identities = 137/406 (33%), Positives = 194/406 (47%), Gaps = 25/406 (6%)

Query: 867  VVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE--GAHVPLQFRSVSGNS 924
            V T   PKPTL A+P  V+  G  V L CQG+ +   + L +E   A    + R     +
Sbjct: 21   VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 925  ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMG 984
              F + ++  E +G Y C YY      R S LS PL++ +T  +PKP L A+PS VV  G
Sbjct: 81   GQFHIPSITWEHTGRYGCQYYSRA---RWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137

Query: 985  QNVTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCC 1039
              VTL C   V   G+IL KEGE    Q   S      S+   F +  +S      + C 
Sbjct: 138  GRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCY 197

Query: 1040 YHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLL 1099
             +   +  +   PS+ LELLV G+  KPSL  QPGP+VAPGE++TLQC  ++    FVL 
Sbjct: 198  GYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLY 257

Query: 1100 KEGAQE----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIW 1155
            KEG ++    P  Q +    +A+F +  V     G Y C Y   +     S  SD L+I 
Sbjct: 258  KEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDIL 316

Query: 1156 VTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE-EAPQQFSE------ 1207
            +T +    P +S  P      G+++TL C+       F+L   G  +AP +         
Sbjct: 317  ITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK 376

Query: 1208 -DGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
               +F ++ V     G Y C   L + P + S PS+PLELV  +GP
Sbjct: 377  YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELV-VSGP 421



 Score =  171 bits (432), Expect = 6e-42
 Identities = 131/399 (32%), Positives = 193/399 (48%), Gaps = 27/399 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           IVT L+C GL  G     T +   T PKP LWAE +  +     +TL C+  S   +E+ 
Sbjct: 4   IVTVLICLGLSLG---PRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYR 59

Query: 624 LLKD--GTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGT 680
           L ++     WI TR   E V+   F + ++T  HTG Y C  +     SE S+ L LV T
Sbjct: 60  LYREKKSASWI-TRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118

Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
              PKP +SA P+     G  + L+C+  +A  GF L KEGE+E  Q L +         
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +      ++ C  +    P+ WS PS+ LEL++  +  KP       PVV PG
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851
             +T  C +   +  F+LYK+G  ++          G S A+F +  V    GG Y C Y
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-Y 297

Query: 852 YDFSIWSE---PSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907
              ++ SE   PSDP+++++T +    P +  QPGP V  G++V L CQ   Q   F L 
Sbjct: 298 GAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLT 357

Query: 908 QEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSC 942
           + G A  PL+ RS+       A+F +  V +  +G Y C
Sbjct: 358 KAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRC 396



 Score =  170 bits (430), Expect = 1e-41
 Identities = 139/414 (33%), Positives = 195/414 (47%), Gaps = 34/414 (8%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS----PGAS 830
            PKP    WA P  V+T G+ VT +C    +   + LY++         SW +        
Sbjct: 27   PKPTL--WAEPDSVITQGSPVTLSCQGSLEAQEYRLYRE-----KKSASWITRIRPELVK 79

Query: 831  AAHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKS 890
               F I S+     G Y C+YY  + WSE SDP+ LV+T  YPKPTL AQP PVV  G  
Sbjct: 80   NGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139

Query: 891  VILRCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945
            V L+C+       F L +EG       +  Q  +   + A F +  V      ++ C  Y
Sbjct: 140  VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199

Query: 946  ETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKE 1005
            +       S  S  L + V     KP L  +P  VV  G+++TL C   V    ++L+KE
Sbjct: 200  DLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKE 259

Query: 1006 GEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVT 1061
            GE    QL G     G     F +  +S +  G+Y  CY     SS    PS+ L++L+T
Sbjct: 260  GERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSECSAPSDPLDILIT 318

Query: 1062 G-LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE-PLE----QQRPSGY 1115
            G +   P +  QPGP VA GEN+TL CQ      TF+L K GA + PL      + P  Y
Sbjct: 319  GQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-Y 377

Query: 1116 RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWP 1169
            +A+F M  V    +G Y C   L+S P+  S+ S+ LE+ V+     PS+ + P
Sbjct: 378  QAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSP 427



 Score =  162 bits (409), Expect = 3e-39
 Identities = 137/442 (30%), Positives = 199/442 (45%), Gaps = 34/442 (7%)

Query: 678  VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGRE 732
            V T  +PKP + A P     +G  + L C+G L    + LY+E +      +    + + 
Sbjct: 21   VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 733  AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
              F I  +  +  G Y C+ ++  R   WSE S+PL LV+   YPKP      SPVVT G
Sbjct: 81   GQFHIPSITWEHTGRYGCQYYSRAR---WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137

Query: 793  ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG-IGDGGNYSCRY 851
             RVT  C +      FIL K+G E      + + P A  +   I SVG +     +S R 
Sbjct: 138  GRVTLQCESQVAFGGFILCKEGEEEHPQCLN-SQPHARGSSRAIFSVGPVSPNRRWSHRC 196

Query: 852  YDFS-----IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906
            Y +      +WS PSD +EL+V     KP+L  QPGPVV PG+S+ L+C       RF L
Sbjct: 197  YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256

Query: 907  LQEG----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962
             +EG      +P +      + A+F L  V     G Y C Y    +S+  S  S PL I
Sbjct: 257  YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDI 315

Query: 963  WVTDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGST 1017
             +T      P++  +P   V  G+NVTL C+       ++L K G A +      +    
Sbjct: 316  LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375

Query: 1018 SNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQP---G 1074
                 FP++ ++    G Y C    +    +   PS  LEL+V+G    PS+ + P   G
Sbjct: 376  KYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSPPPTG 431

Query: 1075 PMVAPG--ENMTLQCQGELPDS 1094
            P+  P   E+  L   G  P S
Sbjct: 432  PISTPAGPEDQPLTPTGSDPQS 453



 Score =  128 bits (322), Expect = 3e-29
 Identities = 117/414 (28%), Positives = 180/414 (43%), Gaps = 20/414 (4%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E +        +TL C+  S  + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYRLYREKK 65

Query: 76  QMTWI---RPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKP 132
             +WI   RP        F I ++T  + G Y C Y+    WS+ S  L L   G  PKP
Sbjct: 66  SASWITRIRPE-LVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKP 124

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G  V + C   +    F+L KEG  E              + AIFS+ 
Sbjct: 125 TLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVG 184

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     + C  +    P +WS PS+ L+L+V G+  KP+L+  PGP++APGESL L+
Sbjct: 185 PVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQ 244

Query: 248 CQGPIYGMTFALMR--VEDLEK-SFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303
           C   +    F L +    DL +      +   ++ANF    +     G Y C+  ++ S 
Sbjct: 245 CVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSS 304

Query: 304 RGSLLSDVLKIWVTDTFPKT-WLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361
             S  SD L I +T     T ++  +P   V  G+NV+L C+         L K G  D 
Sbjct: 305 ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADA 364

Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           PL+             F ++ VT +  G Y C+  L     +       +EL+V
Sbjct: 365 PLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVV 418



 Score =  122 bits (306), Expect = 2e-27
 Identities = 112/409 (27%), Positives = 179/409 (43%), Gaps = 37/409 (9%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G +PKP  W + ++    G  V + C G L+   + L++E  +     ++    +    F
Sbjct: 24  GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C+ + +     WSE S+PL LV+ G YPKPTL+A P P++  G  +
Sbjct: 84  HIPSITWEHTGRYGCQYYSR---ARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRV 140

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296
            L+C+  +    F L +  + E    H + + ++ +    S  I   G         + C
Sbjct: 141 TLQCESQVAFGGFILCKEGEEE----HPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD +  Y  S  SD+L++ V     K  L  +P  VV  G++++L+C   V      L
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256

Query: 355 YKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVE 411
           YK+GE + L+ L         S   F L  V+ S  G Y C+      +    PS     
Sbjct: 257 YKEGE-RDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDI 315

Query: 412 LMVVDKPPKPSLSAWPSTVFKLGKAITLQC---RVSHPVL-------EFSLEWEERETFQ 461
           L+       P +S  P      G+ +TL C   R  H  L       +  L       + 
Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375

Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPA 508
           K+    +F +S V     GTY C   + + P + SH SEPL+L+  GP+
Sbjct: 376 KYQA--EFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPS 422



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 21/219 (9%)

Query: 37  QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92
           +P L ++     AP E++TL C S      +F+L K    D  Q+   +P     Q +F 
Sbjct: 224 KPSLSVQPGPVVAPGESLTLQCVSDVGYD-RFVLYKEGERDLRQLPGRQPQAGLSQANFT 282

Query: 93  IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149
           +G ++ S  G YRC   +   +  S PS  L++   GQ+   P   +Q       G NV 
Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342

Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204
           +LC  W Q   F+L K G A+ P+     ++ P    A F +  +T    G Y C   + 
Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLN 401

Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP---GPIMAP 240
             P L S PS PL+LVV+G    P++ + P   GPI  P
Sbjct: 402 SDPYLLSHPSEPLELVVSG----PSMGSSPPPTGPISTP 436



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 12/200 (6%)

Query: 317 TDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS 376
           T T PK  L A P +V+  G  V+L C+G ++     LY++ +           +  N  
Sbjct: 23  TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82

Query: 377 FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKA 436
           F + ++T+  TG Y C Y    + S      + + L++    PKP+LSA PS V   G  
Sbjct: 83  FHIPSITWEHTGRYGCQYYSRARWS---ELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139

Query: 437 ITLQCRVSHPVLEFSL--EWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYR 487
           +TLQC        F L  E EE        +   + S    F +  V      ++ C   
Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199

Query: 488 VETHPNIWSHRSEPLKLMGP 507
               P +WS  S+ L+L+ P
Sbjct: 200 DLNSPYVWSSPSDLLELLVP 219



 Score = 39.7 bits (91), Expect = 0.020
 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 12/102 (11%)

Query: 602 LAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPAS----EQVRAAFPLGALTQSHTGS 657
           +A  +N+TL C+S       F+L K G      R  S     + +A FP+  +T +H G+
Sbjct: 335 VASGENVTLLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGT 393

Query: 658 YHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIRG 696
           Y C+   + +   +S PSE LELV    +  P + +SP   G
Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELV----VSGPSMGSSPPPTG 431


>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
            member 2 isoform 2 [Homo sapiens]
          Length = 597

 Score =  178 bits (451), Expect = 4e-44
 Identities = 137/406 (33%), Positives = 194/406 (47%), Gaps = 25/406 (6%)

Query: 867  VVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE--GAHVPLQFRSVSGNS 924
            V T   PKPTL A+P  V+  G  V L CQG+ +   + L +E   A    + R     +
Sbjct: 21   VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 925  ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMG 984
              F + ++  E +G Y C YY      R S LS PL++ +T  +PKP L A+PS VV  G
Sbjct: 81   GQFHIPSITWEHTGRYGCQYYSRA---RWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137

Query: 985  QNVTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCC 1039
              VTL C   V   G+IL KEGE    Q   S      S+   F +  +S      + C 
Sbjct: 138  GRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCY 197

Query: 1040 YHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLL 1099
             +   +  +   PS+ LELLV G+  KPSL  QPGP+VAPGE++TLQC  ++    FVL 
Sbjct: 198  GYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLY 257

Query: 1100 KEGAQE----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIW 1155
            KEG ++    P  Q +    +A+F +  V     G Y C Y   +     S  SD L+I 
Sbjct: 258  KEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDIL 316

Query: 1156 VTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE-EAPQQFSE------ 1207
            +T +    P +S  P      G+++TL C+       F+L   G  +AP +         
Sbjct: 317  ITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK 376

Query: 1208 -DGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
               +F ++ V     G Y C   L + P + S PS+PLELV  +GP
Sbjct: 377  YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELV-VSGP 421



 Score =  171 bits (432), Expect = 6e-42
 Identities = 131/399 (32%), Positives = 193/399 (48%), Gaps = 27/399 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           IVT L+C GL  G     T +   T PKP LWAE +  +     +TL C+  S   +E+ 
Sbjct: 4   IVTVLICLGLSLG---PRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYR 59

Query: 624 LLKD--GTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGT 680
           L ++     WI TR   E V+   F + ++T  HTG Y C  +     SE S+ L LV T
Sbjct: 60  LYREKKSASWI-TRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118

Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
              PKP +SA P+     G  + L+C+  +A  GF L KEGE+E  Q L +         
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +      ++ C  +    P+ WS PS+ LEL++  +  KP       PVV PG
Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851
             +T  C +   +  F+LYK+G  ++          G S A+F +  V    GG Y C Y
Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-Y 297

Query: 852 YDFSIWSE---PSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907
              ++ SE   PSDP+++++T +    P +  QPGP V  G++V L CQ   Q   F L 
Sbjct: 298 GAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLT 357

Query: 908 QEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSC 942
           + G A  PL+ RS+       A+F +  V +  +G Y C
Sbjct: 358 KAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRC 396



 Score =  170 bits (430), Expect = 1e-41
 Identities = 139/414 (33%), Positives = 195/414 (47%), Gaps = 34/414 (8%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS----PGAS 830
            PKP    WA P  V+T G+ VT +C    +   + LY++         SW +        
Sbjct: 27   PKPTL--WAEPDSVITQGSPVTLSCQGSLEAQEYRLYRE-----KKSASWITRIRPELVK 79

Query: 831  AAHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKS 890
               F I S+     G Y C+YY  + WSE SDP+ LV+T  YPKPTL AQP PVV  G  
Sbjct: 80   NGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139

Query: 891  VILRCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945
            V L+C+       F L +EG       +  Q  +   + A F +  V      ++ C  Y
Sbjct: 140  VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199

Query: 946  ETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKE 1005
            +       S  S  L + V     KP L  +P  VV  G+++TL C   V    ++L+KE
Sbjct: 200  DLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKE 259

Query: 1006 GEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVT 1061
            GE    QL G     G     F +  +S +  G+Y  CY     SS    PS+ L++L+T
Sbjct: 260  GERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSECSAPSDPLDILIT 318

Query: 1062 G-LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE-PLE----QQRPSGY 1115
            G +   P +  QPGP VA GEN+TL CQ      TF+L K GA + PL      + P  Y
Sbjct: 319  GQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-Y 377

Query: 1116 RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWP 1169
            +A+F M  V    +G Y C   L+S P+  S+ S+ LE+ V+     PS+ + P
Sbjct: 378  QAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSP 427



 Score =  164 bits (416), Expect = 4e-40
 Identities = 138/441 (31%), Positives = 200/441 (45%), Gaps = 33/441 (7%)

Query: 678  VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGRE 732
            V T  +PKP + A P     +G  + L C+G L    + LY+E +      +    + + 
Sbjct: 21   VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 733  AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
              F I  +  +  G Y C+ ++  R   WSE S+PL LV+   YPKP      SPVVT G
Sbjct: 81   GQFHIPSITWEHTGRYGCQYYSRAR---WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137

Query: 793  ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG-IGDGGNYSCRY 851
             RVT  C +      FIL K+G E      + + P A  +   I SVG +     +S R 
Sbjct: 138  GRVTLQCESQVAFGGFILCKEGEEEHPQCLN-SQPHARGSSRAIFSVGPVSPNRRWSHRC 196

Query: 852  YDFS-----IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906
            Y +      +WS PSD +EL+V     KP+L  QPGPVV PG+S+ L+C       RF L
Sbjct: 197  YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256

Query: 907  LQEG----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962
             +EG      +P +      + A+F L  V     G Y C Y    +S+  S  S PL I
Sbjct: 257  YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDI 315

Query: 963  WVTDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGST 1017
             +T      P++  +P   V  G+NVTL C+       ++L K G A +      +    
Sbjct: 316  LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375

Query: 1018 SNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQP---G 1074
                 FP++ ++    G Y C    +    +   PS  LEL+V+G    PS+ + P   G
Sbjct: 376  KYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSPPPTG 431

Query: 1075 PMVAPG-ENMTLQCQGELPDS 1094
            P+  PG E+  L   G  P S
Sbjct: 432  PISTPGPEDQPLTPTGSDPQS 452



 Score =  128 bits (322), Expect = 3e-29
 Identities = 117/414 (28%), Positives = 180/414 (43%), Gaps = 20/414 (4%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E +        +TL C+  S  + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYRLYREKK 65

Query: 76  QMTWI---RPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKP 132
             +WI   RP        F I ++T  + G Y C Y+    WS+ S  L L   G  PKP
Sbjct: 66  SASWITRIRPE-LVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKP 124

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G  V + C   +    F+L KEG  E              + AIFS+ 
Sbjct: 125 TLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVG 184

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     + C  +    P +WS PS+ L+L+V G+  KP+L+  PGP++APGESL L+
Sbjct: 185 PVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQ 244

Query: 248 CQGPIYGMTFALMR--VEDLEK-SFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303
           C   +    F L +    DL +      +   ++ANF    +     G Y C+  ++ S 
Sbjct: 245 CVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSS 304

Query: 304 RGSLLSDVLKIWVTDTFPKT-WLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361
             S  SD L I +T     T ++  +P   V  G+NV+L C+         L K G  D 
Sbjct: 305 ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADA 364

Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           PL+             F ++ VT +  G Y C+  L     +       +EL+V
Sbjct: 365 PLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVV 418



 Score =  122 bits (306), Expect = 2e-27
 Identities = 112/409 (27%), Positives = 179/409 (43%), Gaps = 37/409 (9%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G +PKP  W + ++    G  V + C G L+   + L++E  +     ++    +    F
Sbjct: 24  GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C+ + +     WSE S+PL LV+ G YPKPTL+A P P++  G  +
Sbjct: 84  HIPSITWEHTGRYGCQYYSR---ARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRV 140

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296
            L+C+  +    F L +  + E    H + + ++ +    S  I   G         + C
Sbjct: 141 TLQCESQVAFGGFILCKEGEEE----HPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD +  Y  S  SD+L++ V     K  L  +P  VV  G++++L+C   V      L
Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256

Query: 355 YKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVE 411
           YK+GE + L+ L         S   F L  V+ S  G Y C+      +    PS     
Sbjct: 257 YKEGE-RDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDI 315

Query: 412 LMVVDKPPKPSLSAWPSTVFKLGKAITLQC---RVSHPVL-------EFSLEWEERETFQ 461
           L+       P +S  P      G+ +TL C   R  H  L       +  L       + 
Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375

Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPA 508
           K+    +F +S V     GTY C   + + P + SH SEPL+L+  GP+
Sbjct: 376 KYQA--EFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPS 422



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 21/220 (9%)

Query: 37  QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92
           +P L ++     AP E++TL C S      +F+L K    D  Q+   +P     Q +F 
Sbjct: 224 KPSLSVQPGPVVAPGESLTLQCVSDVGYD-RFVLYKEGERDLRQLPGRQPQAGLSQANFT 282

Query: 93  IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149
           +G ++ S  G YRC   +   +  S PS  L++   GQ+   P   +Q       G NV 
Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342

Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204
           +LC  W Q   F+L K G A+ P+     ++ P    A F +  +T    G Y C   + 
Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLN 401

Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP---GPIMAPG 241
             P L S PS PL+LVV+G    P++ + P   GPI  PG
Sbjct: 402 SDPYLLSHPSEPLELVVSG----PSMGSSPPPTGPISTPG 437



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 12/200 (6%)

Query: 317 TDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS 376
           T T PK  L A P +V+  G  V+L C+G ++     LY++ +           +  N  
Sbjct: 23  TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82

Query: 377 FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKA 436
           F + ++T+  TG Y C Y    + S      + + L++    PKP+LSA PS V   G  
Sbjct: 83  FHIPSITWEHTGRYGCQYYSRARWS---ELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139

Query: 437 ITLQCRVSHPVLEFSL--EWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYR 487
           +TLQC        F L  E EE        +   + S    F +  V      ++ C   
Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199

Query: 488 VETHPNIWSHRSEPLKLMGP 507
               P +WS  S+ L+L+ P
Sbjct: 200 DLNSPYVWSSPSDLLELLVP 219



 Score = 39.7 bits (91), Expect = 0.020
 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 12/102 (11%)

Query: 602 LAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPAS----EQVRAAFPLGALTQSHTGS 657
           +A  +N+TL C+S       F+L K G      R  S     + +A FP+  +T +H G+
Sbjct: 335 VASGENVTLLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGT 393

Query: 658 YHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIRG 696
           Y C+   + +   +S PSE LELV    +  P + +SP   G
Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELV----VSGPSMGSSPPPTG 431


>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
           member 4 [Homo sapiens]
          Length = 499

 Score =  178 bits (451), Expect = 4e-44
 Identities = 134/426 (31%), Positives = 205/426 (48%), Gaps = 30/426 (7%)

Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKN-LTLWCRSPSGST 619
           M  I+T+LL  GL  G     T +     PKP LWAE   P+  W N +T+WC+      
Sbjct: 1   MTLILTSLLFFGLSLG---PRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTL-EA 55

Query: 620 KEFVLLKDGTGW----IATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEAL 675
           + + L K+G       + T  +  +V+ + P  ++   H G YHC+       SEPS+ L
Sbjct: 56  QGYRLDKEGNSMSRHILKTLESENKVKLSIP--SMMWEHAGRYHCYYQSPAGWSEPSDPL 113

Query: 676 ELVGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR- 731
           ELV T    +P +SA P+     G  + LRC   L    F L +EG+      L +    
Sbjct: 114 ELVVT-AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHN 172

Query: 732 ----EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787
               +A F +  +   + G + C  +    P+ WSEPS+PL+L++  +  KP   T   P
Sbjct: 173 HGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGP 232

Query: 788 VVTPGARVTFNCSTPHQHMSFILYKDGSE-IASSDRSWASPGASAAHFLIISVGIGDGGN 846
           VVTPG  +T  C +   ++ + LYK+G++ +          G S A+F +  V    GG 
Sbjct: 233 VVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQ 292

Query: 847 YSC--RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMR 903
           Y C   +   S WS PSDP+++++  +   +P+L  QPGP V  G+ V L CQ       
Sbjct: 293 YRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFT 352

Query: 904 FALLQEG-AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959
           F L +EG AH PL+ RS+ G     A+F +  V +  +G Y C    ++     S+ S P
Sbjct: 353 FLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEP 412

Query: 960 LMIWVT 965
           L + V+
Sbjct: 413 LELVVS 418



 Score =  166 bits (419), Expect = 2e-40
 Identities = 140/453 (30%), Positives = 208/453 (45%), Gaps = 41/453 (9%)

Query: 863  PVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV-- 920
            P   V  E  PKP L A+PGPV+     V + CQGT +   + L +EG  +         
Sbjct: 17   PRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLE 76

Query: 921  SGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSV 980
            S N     + ++  E +G Y C YY++      S  S PL + VT  + +P L A PS V
Sbjct: 77   SENKVKLSIPSMMWEHAGRYHC-YYQSPAG--WSEPSDPLELVVT-AYSRPTLSALPSPV 132

Query: 981  VPMGQNVTLWCRGPVHGVGYILHKEGE-ATSMQLWGSTSNDGAF----PITNISGTSMGR 1035
            V  G NVTL C   +    + L +EG+   S  L     N G F    P+  ++ ++ G 
Sbjct: 133  VTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGT 192

Query: 1036 YSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDST 1095
            + C  + + T  +  +PS+ L+LLV+G+  KPSLL   GP+V PGEN+TLQC  ++    
Sbjct: 193  FRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252

Query: 1096 FVLLKEGA----QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDS 1151
            + L KEGA    Q P  Q +    +A+F +  V     G Y C Y   +     S  SD 
Sbjct: 253  YTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC-YGAHNVSSEWSAPSDP 311

Query: 1152 LEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ------- 1203
            L+I +  +   +PSLS  P      G+ +TL C+   P   F+L  +G   P        
Sbjct: 312  LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMY 371

Query: 1204 -QFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV--------------- 1247
                   +F ++ V     G Y C     + P + S PS+PLELV               
Sbjct: 372  GAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKS 431

Query: 1248 -GAAGPVAQECTVGNIVRSSLIVVVVVALGVVL 1279
                 P  Q+ TV N++R  +  +V++ LG++L
Sbjct: 432  DSKTAPHLQDYTVENLIRMGVAGLVLLFLGILL 464



 Score =  128 bits (322), Expect = 3e-29
 Identities = 119/398 (29%), Positives = 176/398 (44%), Gaps = 28/398 (7%)

Query: 129 LPKPIFWIQAETPALPGCN-VNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIFS 185
           LPKPI W +   P +   N V I C G L+   + L KEG   +  +   + +      S
Sbjct: 26  LPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84

Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245
           I ++  E  G Y C       P  WSEPS+PL+LVV   Y +PTL+A P P++  G ++ 
Sbjct: 85  IPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVT 140

Query: 246 LRCQGPIYGMTFALMRVEDLEKSF----YHKKTIKNEANFFFQSLKIQDTGHYLCFYYDA 301
           LRC   +    F L+   D   S+    +     K +A F    L   + G + C+ Y+ 
Sbjct: 141 LRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYEN 200

Query: 302 S--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359
           +  Y  S  SD L++ V+    K  LL     VV  G+N++L+C   V  +   LYK+G 
Sbjct: 201 NTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGA 260

Query: 360 D----KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVV 415
           D    +P +   A     N  F L+ V+ S  G Y C+      +    PS     L+  
Sbjct: 261 DGLPQRPGRQPQAGLSQAN--FTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAG 318

Query: 416 DKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVNG 467
               +PSLS  P      G+ +TL C+   P+  F L  E         R  +       
Sbjct: 319 QISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQA 378

Query: 468 DFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
           +F +S V     GTY C     ++P + SH SEPL+L+
Sbjct: 379 EFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELV 416



 Score =  112 bits (281), Expect = 2e-24
 Identities = 113/402 (28%), Positives = 172/402 (42%), Gaps = 26/402 (6%)

Query: 12  MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWEN-ITLWCRSPSRISSK 67
           M    T LLF   +SLG  + V     P+P LW E   P   W N +T+WC+        
Sbjct: 1   MTLILTSLLF-FGLSLGPRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGY 58

Query: 68  FLLLKDKTQMTWIRPSHKTFQ----VSFLIGALTESNAGLYRCCYWKETGWSKPSKVLEL 123
            L   DK   +  R   KT +    V   I ++   +AG Y C Y    GWS+PS  LEL
Sbjct: 59  RL---DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLEL 115

Query: 124 EAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPV----DYQVPTG 179
                  +P            G NV + C   L    F L +EG          +Q   G
Sbjct: 116 VVTAY-SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG 174

Query: 180 TM-AIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIM 238
              A+F +  LT  + G + C  +    P +WSEPS+PL+L+V+G+  KP+L    GP++
Sbjct: 175 KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVV 234

Query: 239 APGESLNLRCQGPIYGMTFALMR--VEDL-EKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295
            PGE+L L+C   +  + + L +   + L ++     +   ++ANF    +     G Y 
Sbjct: 235 TPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294

Query: 296 CF-YYDASYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLA 353
           C+  ++ S   S  SD L I +      +  L  +P   V  G+ V+L C+         
Sbjct: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354

Query: 354 LYKKGEDKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393
           L K+G   P   L +   +      F ++ VT +  G Y C+
Sbjct: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 396



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 57/185 (30%), Positives = 81/185 (43%), Gaps = 12/185 (6%)

Query: 50  PWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKT----FQVSFLIGALTESNAGLYR 105
           P EN+TL C S      ++ L K+       RP  +      Q +F +  ++ S  G YR
Sbjct: 236 PGENLTLQCGSDVGYI-RYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294

Query: 106 C--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVNILCHGWLQDLVFM 162
           C   +   + WS PS  L++   GQ+  +P   +Q       G  V +LC  W     F+
Sbjct: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354

Query: 163 LFKEGYAEP-VDYQVPTGT---MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLK 218
           L KEG A P +  +   G     A F +  +T    G Y C       P L S PS PL+
Sbjct: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLE 414

Query: 219 LVVAG 223
           LVV+G
Sbjct: 415 LVVSG 419



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 15/198 (7%)

Query: 318 DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSF 377
           +  PK  L A P  V+     V++ C+G ++  G  L K+G       L     ++    
Sbjct: 24  ENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKL 83

Query: 378 FLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAI 437
            + ++ +   G Y C+Y      S   PS + +EL VV    +P+LSA PS V   G  +
Sbjct: 84  SIPSMMWEHAGRYHCYYQSPAGWS--EPS-DPLEL-VVTAYSRPTLSALPSPVVTSGVNV 139

Query: 438 TLQCRVSHPVLEFSLEWEERETFQKFSVNGD----------FIISNVDGKGTGTYSCSYR 487
           TL+C     +  F+L  EE +    +++N            F +  +     GT+ C   
Sbjct: 140 TLRCASRLGLGRFTL-IEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198

Query: 488 VETHPNIWSHRSEPLKLM 505
               P +WS  S+PL+L+
Sbjct: 199 ENNTPYVWSEPSDPLQLL 216


>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 1 [Homo sapiens]
          Length = 489

 Score =  177 bits (450), Expect = 5e-44
 Identities = 135/407 (33%), Positives = 187/407 (45%), Gaps = 26/407 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           IVT L+C  L  G     T +   T PKP LWAE    +     +TLWC+     T+E+ 
Sbjct: 4   IVTVLICLRLSLG---PRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGIL-ETQEYR 59

Query: 624 LL--KDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMA-VSEPSEALELVGT 680
           L   K    WI   P     +  FP+ ++T  HTG Y C      A  SEPS+ LELV T
Sbjct: 60  LYREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVT 119

Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR-----E 732
               KP +SA P+     G  + L C   +A   F L KEGE E  Q L +  R      
Sbjct: 120 GAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSR 179

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +      +Y C  +    P  WS PS+ LEL++  +  KP       P+V PG
Sbjct: 180 AIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPG 239

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849
             +T  C +   +  F+LYK+G  +           G S A+F +  V    GG Y C  
Sbjct: 240 ESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSG 299

Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            Y   S WS PSDP+++++  +F  +P +   PGP V  G++V L CQ       F L +
Sbjct: 300 AYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTK 359

Query: 909 EG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSCIYYETTMSN 951
            G A  PL+ RS+       A+F +  V +  SG Y C  Y +  SN
Sbjct: 360 AGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRC--YGSLSSN 404



 Score =  169 bits (428), Expect = 2e-41
 Identities = 146/458 (31%), Positives = 205/458 (44%), Gaps = 56/458 (12%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSG--NSADFLLH 930
            PKPTL A+PG V+  G  V L CQG  +   + L +E    P   R          F + 
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPIP 86

Query: 931  TVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLW 990
            ++  E +G Y C Y   T     S  S PL + VT  + KP L A PS VV  G NVTL 
Sbjct: 87   SITWEHTGRYRCFYGSHTAG--WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNVTLH 144

Query: 991  CRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWT 1045
            C   V    +IL KEGE    Q   S           F +  +S +    Y C  +   +
Sbjct: 145  CVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNS 204

Query: 1046 SSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE 1105
              +   PS+ LELLV G+  KPSL  QPGP+VAPGE++TLQC  ++    FVL KEG ++
Sbjct: 205  PHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERD 264

Query: 1106 PLEQQRPSGY----RADFWMPAVRGEDSGIYSC--VYYLDSTPFAASNHSDSLEIWVTDK 1159
             L+   P       +A+F +  V     G Y C   Y L S     S  SD L+I +  +
Sbjct: 265  FLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSS---EWSAPSDPLDILIAGQ 321

Query: 1160 -PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG-EEAPQQFSE-------DGD 1210
               +P +S  P      G+++TL C+   P   F+L   G  +AP +            +
Sbjct: 322  FRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAE 381

Query: 1211 FVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-------------------GAAG 1251
            F ++ V     G Y C   L + P + S PSD LEL+                   GAA 
Sbjct: 382  FPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAAN 441

Query: 1252 PVA----------QECTVGNIVRSSLIVVVVVALGVVL 1279
             ++          Q+ TV N++R  +  +V+V LG++L
Sbjct: 442  TLSPSQNKTASHPQDYTVENLIRMGIAGLVLVVLGILL 479



 Score =  158 bits (399), Expect = 4e-38
 Identities = 131/406 (32%), Positives = 188/406 (46%), Gaps = 36/406 (8%)

Query: 683  LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGREAFFTI 737
            LPKP + A P     +G  + L C+G L    + LY+E +  P   +    + ++  F I
Sbjct: 26   LPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPI 85

Query: 738  QRMEDKDEGNYSC--RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARV 795
              +  +  G Y C   +HT      WSEPS+PLELV+   Y KP      SPVVT G  V
Sbjct: 86   PSITWEHTGRYRCFYGSHTAG----WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141

Query: 796  TFNCSTPHQHMSFILYKDGSE-----IASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850
            T +C +     SFIL K+G +     + S  R   + G S A F +  V      +Y C 
Sbjct: 142  TLHCVSQVAFGSFILCKEGEDEHPQCLNSQPR---THGWSRAIFSVGPVSPSRRWSYRCY 198

Query: 851  YYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907
             YD +   +WS PSD +EL+V     KP+L  QPGP+V PG+S+ L+C       RF L 
Sbjct: 199  AYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLY 258

Query: 908  QEGAHVPLQF----RSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIW 963
            +EG    LQ          + A+F L  V     G Y C      +S+  S  S PL I 
Sbjct: 259  KEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRC-SGAYNLSSEWSAPSDPLDIL 317

Query: 964  VTDTF-PKPWLFAEPSSVVPMGQNVTLWCR--GPVHGVGYILHKEGEATS----MQLWGS 1016
            +   F  +P++   P   V  G+NVTL C+  GP H   ++L K G A +      +   
Sbjct: 318  IAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFH--TFLLTKAGAADAPLRLRSIHEY 375

Query: 1017 TSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG 1062
                  FP++ ++    G Y C         +   PS++LEL+V+G
Sbjct: 376  PKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSG 421



 Score =  150 bits (378), Expect = 1e-35
 Identities = 107/301 (35%), Positives = 146/301 (48%), Gaps = 28/301 (9%)

Query: 967  TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS--MQLWGSTSNDGAFP 1024
            T PKP L+AEP SV+  G  VTLWC+G +    Y L++E +      ++       G FP
Sbjct: 25   TLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFP 84

Query: 1025 ITNISGTSMGRYSCCY---HPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGE 1081
            I +I+    GRY C Y      W+     +PS+ LEL+VTG   KP+L A P P+V  G 
Sbjct: 85   IPSITWEHTGRYRCFYGSHTAGWS-----EPSDPLELVVTGAYIKPTLSALPSPVVTSGG 139

Query: 1082 NMTLQCQGELPDSTFVLLKEGAQEPLE----QQRPSGY-RADFWMPAVRGEDSGIYSCVY 1136
            N+TL C  ++   +F+L KEG  E  +    Q R  G+ RA F +  V       Y C  
Sbjct: 140  NVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYA 199

Query: 1137 YLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEH 1196
            Y  ++P   S  SD LE+ V     KPSLS  P  +   G+ +TLQC   +    FVL  
Sbjct: 200  YDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYK 259

Query: 1197 DGEE--------APQQFSEDGDFVINNVEGKGIGNYSCS--YRLQAYPDIWSEPSDPLEL 1246
            +GE          PQ      +F +  V     G Y CS  Y L +    WS PSDPL++
Sbjct: 260  EGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSE---WSAPSDPLDI 316

Query: 1247 V 1247
            +
Sbjct: 317  L 317



 Score =  147 bits (370), Expect = 9e-35
 Identities = 124/414 (29%), Positives = 189/414 (45%), Gaps = 19/414 (4%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+R+SLG  + V     P+P LW E          +TLWC+     + ++ L ++K 
Sbjct: 7   VLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILE-TQEYRLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  + G YRC Y   T GWS+PS  LEL   G   KP
Sbjct: 66  TAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKP 125

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG---YAEPVDYQVPTG--TMAIFSID 187
                       G NV + C   +    F+L KEG   + + ++ Q  T   + AIFS+ 
Sbjct: 126 TLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVG 185

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P +WS PS+ L+L+V G+  KP+L+  PGPI+APGESL L+
Sbjct: 186 PVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQ 245

Query: 248 CQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303
           C   +    F L +  +   L+      +   ++ANF    +     G Y C   Y+ S 
Sbjct: 246 CVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSS 305

Query: 304 RGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361
             S  SD L I +   F  + ++   P   V  G+NV+L C+         L K G  D 
Sbjct: 306 EWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADA 365

Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           PL+             F ++ VT + +G Y C+  L+    +     +++ELMV
Sbjct: 366 PLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMV 419



 Score =  128 bits (322), Expect = 3e-29
 Identities = 111/401 (27%), Positives = 172/401 (42%), Gaps = 28/401 (6%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G L+   + L++E    P   ++P   +    F
Sbjct: 24  GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C          WSEPS+PL+LVV G Y KPTL+A P P++  G ++
Sbjct: 84  PIPSITWEHTGRYRCFYGSHTAG--WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296
            L C   +   +F L +  + E    H + + ++      S  I   G         Y C
Sbjct: 142 TLHCVSQVAFGSFILCKEGEDE----HPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRC 197

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD++  +  SL SD+L++ V     K  L  +P  +V  G++++L+C   V      L
Sbjct: 198 YAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVL 257

Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           YK+GE   LQ             +F L  V+ S  G Y C       +    PS     L
Sbjct: 258 YKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDIL 317

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464
           +      +P +S  P      G+ +TL C+   P   F L            R   +   
Sbjct: 318 IAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPK 377

Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
              +F +S V    +GTY C   + ++P + SH S+ L+LM
Sbjct: 378 YQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELM 418



 Score =  103 bits (256), Expect = 1e-21
 Identities = 91/304 (29%), Positives = 130/304 (42%), Gaps = 17/304 (5%)

Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYH-KKT 274
           P   V AG  PKPTL A PG ++  G  + L CQG +    + L R +          + 
Sbjct: 17  PRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQE 76

Query: 275 IKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQ 334
           I  +  F   S+  + TG Y CFY   +   S  SD L++ VT  + K  L A PS VV 
Sbjct: 77  IVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVT 136

Query: 335 MGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYS 391
            G NV+L C   V      L K+GED+  Q L++       S   F +  V+ S    Y 
Sbjct: 137 SGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYR 196

Query: 392 CHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFS 451
           C+   +    +     + +EL+V+    KPSLS  P  +   G+++TLQC        F 
Sbjct: 197 CYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFV 256

Query: 452 LEWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCS--YRVETHPNIWSHRSEP 501
           L  E    F        Q      +F +  V     G Y CS  Y + +    WS  S+P
Sbjct: 257 LYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSE---WSAPSDP 313

Query: 502 LKLM 505
           L ++
Sbjct: 314 LDIL 317



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 66/197 (33%), Positives = 92/197 (46%), Gaps = 13/197 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL CQG L    + L +E    P   + P     +  F
Sbjct: 24   GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++  E +G Y C Y   S     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PIPSITWEHTGRYRCFY--GSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSED--------GDFVINNVEGKGIGNYSCSYRL 1230
            TL C   +    F+L  +GE E PQ  +            F +  V      +Y C    
Sbjct: 142  TLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYD 201

Query: 1231 QAYPDIWSEPSDPLELV 1247
               P +WS PSD LEL+
Sbjct: 202  SNSPHVWSLPSDLLELL 218



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 60/199 (30%), Positives = 91/199 (45%), Gaps = 14/199 (7%)

Query: 37  QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92
           +P L ++     AP E++TL C S      +F+L K    D  Q+   +P     Q +F 
Sbjct: 225 KPSLSVQPGPIVAPGESLTLQCVSDVSYD-RFVLYKEGERDFLQLPGPQPQAGLSQANFT 283

Query: 93  IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149
           +G ++ S  G YRC   Y   + WS PS  L++   GQ   +P   +        G NV 
Sbjct: 284 LGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVT 343

Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204
           +LC  W     F+L K G A+ P+     ++ P    A F +  +T    G Y C   + 
Sbjct: 344 LLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHSGTYRCYGSLS 402

Query: 205 MLPTLWSEPSNPLKLVVAG 223
             P L S PS+ L+L+V+G
Sbjct: 403 SNPYLLSHPSDSLELMVSG 421



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 10/100 (10%)

Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETF-------QKFSVNGDFII 471
           PKP+L A P +V   G  +TL C+      E+ L + E++T        Q+    G F I
Sbjct: 27  PKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL-YREKKTAPWITRIPQEIVKKGQFPI 85

Query: 472 SNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYL 511
            ++  + TG Y C Y   +H   WS  S+PL+L+    Y+
Sbjct: 86  PSITWEHTGRYRCFYG--SHTAGWSEPSDPLELVVTGAYI 123


>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
           (without TM domain), member 3 [Homo sapiens]
          Length = 439

 Score =  177 bits (449), Expect = 6e-44
 Identities = 132/410 (32%), Positives = 197/410 (48%), Gaps = 26/410 (6%)

Query: 562 MLFIVTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620
           M  I+T L+C GL    L   T +   P PKP LWAE    +     +TL C+  S  T+
Sbjct: 1   MTSILTVLICLGLS---LDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQ 56

Query: 621 EFVLLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHC-HSWEEMAVSEPSEALEL 677
           E+ L ++     WI   P     +  FP+ ++T  H G Y C +    + +SE S+ LEL
Sbjct: 57  EYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLEL 116

Query: 678 VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR--- 731
           V T    KP +SA P+     G  + ++C   +A  GF L KEGE E  Q L +      
Sbjct: 117 VVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARG 176

Query: 732 --EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVV 789
              A F++  +      +Y C  +  + P+ WS PS+ L L++  +  KP       PVV
Sbjct: 177 SSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVV 236

Query: 790 TPGARVTFNCSTPHQHMSFILYKD-GSEIASSDRSWASPGASAAHFLIISVGIGDGGNYS 848
            PG ++TF C +   +  F+LYK+ G +           G S A+F +  V    GG Y+
Sbjct: 237 APGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYT 296

Query: 849 C--RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFA 905
           C   Y   S WS PSDP+++++T +   +P L  +PGP V  G++V L CQ       F 
Sbjct: 297 CSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFL 356

Query: 906 LLQEG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSN 951
           L +EG A  PL+ +S   +    A+F +  V +  +G Y C  Y +  SN
Sbjct: 357 LTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRC--YGSLSSN 404



 Score =  168 bits (426), Expect = 3e-41
 Identities = 140/417 (33%), Positives = 190/417 (45%), Gaps = 37/417 (8%)

Query: 862  DPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPL 915
            DP   V     PKPTL A+PG V+  G  V LRCQG+ +   + L +E         +P 
Sbjct: 16   DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75

Query: 916  QFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFA 975
            +          F + ++  E +G Y CIY   T+    S  S PL + VT  + KP L A
Sbjct: 76   ELVK----KGQFPILSITWEHAGRYCCIYGSHTVGLSES--SDPLELVVTGAYSKPTLSA 129

Query: 976  EPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISG 1030
             PS VV  G NVT+ C   V   G+IL KEGE    Q   S S+        F +  +S 
Sbjct: 130  LPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSP 189

Query: 1031 TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGE 1090
            +    Y C  +      +   PS+ L LLV G+  KPSL  QPGP+VAPGE +T QC  +
Sbjct: 190  SRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSD 249

Query: 1091 LPDSTFVLLKEGA----QEPLEQQRPSGYRADFWMPAVRGEDSGIYSC--VYYLDSTPFA 1144
                 FVL KE      Q P  Q +    +A+F +  V     G Y+C   Y L S    
Sbjct: 250  AGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSS---E 306

Query: 1145 ASNHSDSLEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----- 1198
             S  SD L+I +T +   +P LS  P      G+++TL C+       F+L  +G     
Sbjct: 307  WSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSP 366

Query: 1199 ---EEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV--GAA 1250
               +   Q      +F ++ V     G Y C   L + P + + PSDPLELV  GAA
Sbjct: 367  LRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSGAA 423



 Score =  127 bits (320), Expect = 5e-29
 Identities = 119/420 (28%), Positives = 180/420 (42%), Gaps = 19/420 (4%)

Query: 13  LKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFL 69
           + +   +L C+ +SL   + V     P+P LW E          +TL C+  S  + ++ 
Sbjct: 1   MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYH 59

Query: 70  LLKDKTQMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAP 126
           L ++K    WI   P     +  F I ++T  +AG Y C Y   T G S+ S  LEL   
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVT 119

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTM 181
           G   KP            G NV I C   +    F+L KEG  E              + 
Sbjct: 120 GAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSR 179

Query: 182 AIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPG 241
           AIFS+  ++P     Y C  +    P +WS PS+ L L+V G+  KP+L+  PGP++APG
Sbjct: 180 AIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPG 239

Query: 242 ESLNLRCQGPIYGMTFALMRV---EDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF- 297
           E L  +C        F L +    + L++     +   ++ANF    +     G Y C  
Sbjct: 240 EKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSG 299

Query: 298 YYDASYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356
            Y+ S   S  SD L I +T     + +L  RP   V  G+NV+L C+         L K
Sbjct: 300 AYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTK 359

Query: 357 KG-EDKPLQFLD-ATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414
           +G  D PL+      S      F ++ VT +  G Y C+  L+    +     + +EL+V
Sbjct: 360 EGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVV 419



 Score =  113 bits (283), Expect = 1e-24
 Identities = 110/407 (27%), Positives = 170/407 (41%), Gaps = 40/407 (9%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G L+   + L++E        ++P   +    F
Sbjct: 24  GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQF 83

Query: 185 SIDNLTPEDEGVYIC--RTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGE 242
            I ++T E  G Y C   +H   L    SE S+PL+LVV G Y KPTL+A P P++  G 
Sbjct: 84  PILSITWEHAGRYCCIYGSHTVGL----SESSDPLELVVTGAYSKPTLSALPSPVVTSGG 139

Query: 243 SLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HY 294
           ++ ++C   +    F L +  + E    H + + + ++    S  I   G         Y
Sbjct: 140 NVTIQCDSQVAFDGFILCKEGEDE----HPQCLNSHSHARGSSRAIFSVGPVSPSRRWSY 195

Query: 295 LCFYYD--ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGL 352
            C+ YD  A Y  SL SD+L + V     K  L  +P  VV  G+ ++ +C         
Sbjct: 196 RCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRF 255

Query: 353 ALYKK-GEDKPLQFLDATSID-----DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPS 406
            LYK+ G D    FL              +F L  V+ S  G Y+C       +    PS
Sbjct: 256 VLYKEWGRD----FLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPS 311

Query: 407 HNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RE 458
                L+      +P LS  P      G+ +TL C+    +  F L  E         + 
Sbjct: 312 DPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKS 371

Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
             Q      +F +S V     GTY C   + ++P + +H S+PL+L+
Sbjct: 372 KRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELV 418



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 88/302 (29%), Positives = 133/302 (44%), Gaps = 28/302 (9%)

Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTG-----WIATRPASEQVRAAF 645
           KP L A  +  +    N+T+ C S   +   F+L K+G         +   A    RA F
Sbjct: 124 KPTLSALPSPVVTSGGNVTIQCDSQV-AFDGFILCKEGEDEHPQCLNSHSHARGSSRAIF 182

Query: 646 PLGALTQSHTGSYHCHSWEEMAV---SEPSEALELVGTDILPKPVISASP---TIRGQEL 699
            +G ++ S   SY C+ ++  A    S PS+ L L+   +  KP +S  P      G++L
Sbjct: 183 SVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKL 242

Query: 700 QLRCKGWLAGMGFALYKEGE----QEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTE 755
             +C        F LYKE      Q P +Q  A   +A FT+  +     G Y+C +   
Sbjct: 243 TFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTC-SGAY 301

Query: 756 KRPFKWSEPSEPLELVIK-EMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDG 814
               +WS PS+PL+++I  ++  +PF      P V  G  VT  C +     +F+L K+G
Sbjct: 302 NLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEG 361

Query: 815 SEIASSDRSWASPGAS---AAHFLIISVGIGDGGNYSCRYYDFS----IWSEPSDPVELV 867
           +  A S     S   S    A F +  V     G Y C Y   S    + + PSDP+ELV
Sbjct: 362 A--ADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRC-YGSLSSNPYLLTHPSDPLELV 418

Query: 868 VT 869
           V+
Sbjct: 419 VS 420



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 12/208 (5%)

Query: 27  LGMTSIVMDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRP 82
           LG+    +  +P L ++     AP E +T  C S +    +F+L K    D  Q    +P
Sbjct: 215 LGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYD-RFVLYKEWGRDFLQRPGRQP 273

Query: 83  SHKTFQVSFLIGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQL-PKPIFWIQAE 139
                Q +F +G ++ S  G Y C   Y   + WS PS  L++   GQ+  +P   ++  
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPG 333

Query: 140 TPALPGCNVNILCHGWLQDLVFMLFKEGYAE-PVDYQVPTGT---MAIFSIDNLTPEDEG 195
                G NV +LC        F+L KEG A+ P+  +    +    A F +  +T    G
Sbjct: 334 PTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAG 393

Query: 196 VYICRTHIQMLPTLWSEPSNPLKLVVAG 223
            Y C   +   P L + PS+PL+LVV+G
Sbjct: 394 TYRCYGSLSSNPYLLTHPSDPLELVVSG 421



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 11/196 (5%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380
           PK  L A P +V+  G  V+LRC+G ++     LY++ +           +     F + 
Sbjct: 27  PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86

Query: 381 NVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQ 440
           ++T+   G Y C Y     T     S + +EL+V     KP+LSA PS V   G  +T+Q
Sbjct: 87  SITWEHAGRYCCIY--GSHTVGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQ 144

Query: 441 C--RVSHPVLEFSLEWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETH 491
           C  +V+        E E+         +  + S    F +  V      +Y C       
Sbjct: 145 CDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRA 204

Query: 492 PNIWSHRSEPLKLMGP 507
           P +WS  S+ L L+ P
Sbjct: 205 PYVWSLPSDLLGLLVP 220


>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 3 [Homo sapiens]
          Length = 651

 Score =  172 bits (436), Expect = 2e-42
 Identities = 139/458 (30%), Positives = 210/458 (45%), Gaps = 27/458 (5%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+     T+E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59

Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680
           L ++     WI   P     +  FP+ ++T  H G Y C+   + A  SE S+ LELV T
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119

Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
               KP +SA P+     G  + L+C   +A  GF+L KEGE E  Q L +         
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +       Y C  +    P++WS PS+ LEL++  +  KP       P+V P 
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849
             +T  C +   +  F+LYKDG  +      +    G S A+F +  V    GG Y C  
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299

Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            +   S WS PSDP+++++  +FY + +L  QPGP V  G++V L CQ       F L +
Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359

Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
           EG A  P + RS   +    A+F +  V +  +G Y C   +++     ++ S PL + V
Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419

Query: 965 TDTF---PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVG 999
           +        P      +S  P  Q +T     P  G+G
Sbjct: 420 SGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLG 457



 Score =  159 bits (401), Expect = 2e-38
 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+T G+ VT  C    +   + LY++        R           F
Sbjct: 27   PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83

Query: 835  LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
             I S+     G Y C Y  D +  SE SDP+ELVVT  Y KPTL AQP PVV  G +VIL
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            +C        F+L +EG       +  Q  +   + A F +  V       Y C  Y++ 
Sbjct: 144  QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S  S  L + V     KP L  +P  +V   + +TL C        ++L+K+GE 
Sbjct: 204  SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +QL G+    G     F +  +S +  G+Y  CY     SS    PS+ L++L+ G  
Sbjct: 264  DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119
              + SL  QPGP VA GEN+TL CQ +    TF+L KEGA +   + R +     Y+A+F
Sbjct: 323  YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164
             M  V    +G Y C     S P+  ++ SD LE+ V+     PS
Sbjct: 383  PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427



 Score =  155 bits (391), Expect = 3e-37
 Identities = 139/451 (30%), Positives = 199/451 (44%), Gaps = 49/451 (10%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926
            PKPTL A+PG V+  G  V LRCQG  +   + L +E         +P +          
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + ++  E +G Y C Y   T     S  S PL + VT  + KP L A+PS VV  G N
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041
            V L C   V   G+ L KEGE    Q   S      S+   F +  +S +    Y C  +
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200

Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101
               +      PS+ LELLV G+  KPSL  QPGP+VAP E +TLQC  +   + FVL K+
Sbjct: 201  DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260

Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
            G ++ L+    Q +    +A+F +  V     G Y C Y   +     S  SD L+I + 
Sbjct: 261  GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319

Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208
             +   + SLS  P      G+++TL C+       F+L  +G            Q     
Sbjct: 320  GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379

Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-----------------GAAG 1251
             +F +  V     G Y C     + P + + PSDPLELV                  +AG
Sbjct: 380  AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439

Query: 1252 PVAQECT-VGNIVRSSLIVVVVVALGVVLAI 1281
            P  Q  T  G+  +S L   + V +G+++A+
Sbjct: 440  PEDQPLTPTGSDPQSGLGRHLGVVIGILVAV 470



 Score =  125 bits (315), Expect = 2e-28
 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+     + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  +AG YRC Y  +T G S+ S  LEL   G   KP
Sbjct: 66  TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G NV + C   +    F L KEG  E              + AIFS+ 
Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P  WS PS+ L+L+V G+  KP+L+  PGPI+AP E+L L+
Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245

Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301
           C        F L +  D E+ F      +     ++ANF    +     G Y C+  ++ 
Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303

Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359
           S   S  SD L I +   F  +  L  +P   V  G+NV+L C+         L K+G  
Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363

Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418
           D P +      S      F +  VT +  G Y C+   + K  +     + +EL+V    
Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423

Query: 419 PKPS 422
             PS
Sbjct: 424 GGPS 427



 Score =  124 bits (311), Expect = 6e-28
 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G  +   + L++E        ++P   +    F
Sbjct: 24  GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C           SE S+PL+LVV G Y KPTL+A P P++  G ++
Sbjct: 84  PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296
            L+C   +    F+L +  + E    H + + ++ +    S  I   G         Y C
Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD++  Y  SL SD+L++ V     K  L  +P  +V   + ++L+C          L
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257

Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           YK GE   LQ   A         +F L  V+ S  G Y C+      +    PS     L
Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464
           +      + SLS  P      G+ +TL C+    +  F L         W  R T+Q   
Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377

Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
              +F +  V     GTY C     + P + +H S+PL+L+  GP+G
Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL+CQG      + L +E        + P     +  F
Sbjct: 24   GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++  E +G Y C Y  D+     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233
             LQC   +    F L  +GE E PQ  +       ++     +G  S S    YR  AY 
Sbjct: 142  ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201

Query: 1234 ---PDIWSEPSDPLELV 1247
               P  WS PSD LEL+
Sbjct: 202  SNSPYEWSLPSDLLELL 218


>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 2 [Homo sapiens]
          Length = 652

 Score =  172 bits (436), Expect = 2e-42
 Identities = 139/458 (30%), Positives = 210/458 (45%), Gaps = 27/458 (5%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+     T+E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59

Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680
           L ++     WI   P     +  FP+ ++T  H G Y C+   + A  SE S+ LELV T
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119

Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
               KP +SA P+     G  + L+C   +A  GF+L KEGE E  Q L +         
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +       Y C  +    P++WS PS+ LEL++  +  KP       P+V P 
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849
             +T  C +   +  F+LYKDG  +      +    G S A+F +  V    GG Y C  
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299

Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            +   S WS PSDP+++++  +FY + +L  QPGP V  G++V L CQ       F L +
Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359

Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
           EG A  P + RS   +    A+F +  V +  +G Y C   +++     ++ S PL + V
Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419

Query: 965 TDTF---PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVG 999
           +        P      +S  P  Q +T     P  G+G
Sbjct: 420 SGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLG 457



 Score =  159 bits (401), Expect = 2e-38
 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+T G+ VT  C    +   + LY++        R           F
Sbjct: 27   PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83

Query: 835  LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
             I S+     G Y C Y  D +  SE SDP+ELVVT  Y KPTL AQP PVV  G +VIL
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            +C        F+L +EG       +  Q  +   + A F +  V       Y C  Y++ 
Sbjct: 144  QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S  S  L + V     KP L  +P  +V   + +TL C        ++L+K+GE 
Sbjct: 204  SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +QL G+    G     F +  +S +  G+Y  CY     SS    PS+ L++L+ G  
Sbjct: 264  DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119
              + SL  QPGP VA GEN+TL CQ +    TF+L KEGA +   + R +     Y+A+F
Sbjct: 323  YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164
             M  V    +G Y C     S P+  ++ SD LE+ V+     PS
Sbjct: 383  PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427



 Score =  155 bits (391), Expect = 3e-37
 Identities = 139/451 (30%), Positives = 199/451 (44%), Gaps = 49/451 (10%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926
            PKPTL A+PG V+  G  V LRCQG  +   + L +E         +P +          
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + ++  E +G Y C Y   T     S  S PL + VT  + KP L A+PS VV  G N
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041
            V L C   V   G+ L KEGE    Q   S      S+   F +  +S +    Y C  +
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200

Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101
               +      PS+ LELLV G+  KPSL  QPGP+VAP E +TLQC  +   + FVL K+
Sbjct: 201  DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260

Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
            G ++ L+    Q +    +A+F +  V     G Y C Y   +     S  SD L+I + 
Sbjct: 261  GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319

Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208
             +   + SLS  P      G+++TL C+       F+L  +G            Q     
Sbjct: 320  GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379

Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-----------------GAAG 1251
             +F +  V     G Y C     + P + + PSDPLELV                  +AG
Sbjct: 380  AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439

Query: 1252 PVAQECT-VGNIVRSSLIVVVVVALGVVLAI 1281
            P  Q  T  G+  +S L   + V +G+++A+
Sbjct: 440  PEDQPLTPTGSDPQSGLGRHLGVVIGILVAV 470



 Score =  125 bits (315), Expect = 2e-28
 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+     + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  +AG YRC Y  +T G S+ S  LEL   G   KP
Sbjct: 66  TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G NV + C   +    F L KEG  E              + AIFS+ 
Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P  WS PS+ L+L+V G+  KP+L+  PGPI+AP E+L L+
Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245

Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301
           C        F L +  D E+ F      +     ++ANF    +     G Y C+  ++ 
Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303

Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359
           S   S  SD L I +   F  +  L  +P   V  G+NV+L C+         L K+G  
Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363

Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418
           D P +      S      F +  VT +  G Y C+   + K  +     + +EL+V    
Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423

Query: 419 PKPS 422
             PS
Sbjct: 424 GGPS 427



 Score =  124 bits (311), Expect = 6e-28
 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G  +   + L++E        ++P   +    F
Sbjct: 24  GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C           SE S+PL+LVV G Y KPTL+A P P++  G ++
Sbjct: 84  PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296
            L+C   +    F+L +  + E    H + + ++ +    S  I   G         Y C
Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD++  Y  SL SD+L++ V     K  L  +P  +V   + ++L+C          L
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257

Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           YK GE   LQ   A         +F L  V+ S  G Y C+      +    PS     L
Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464
           +      + SLS  P      G+ +TL C+    +  F L         W  R T+Q   
Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377

Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
              +F +  V     GTY C     + P + +H S+PL+L+  GP+G
Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL+CQG      + L +E        + P     +  F
Sbjct: 24   GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++  E +G Y C Y  D+     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233
             LQC   +    F L  +GE E PQ  +       ++     +G  S S    YR  AY 
Sbjct: 142  ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201

Query: 1234 ---PDIWSEPSDPLELV 1247
               P  WS PSD LEL+
Sbjct: 202  SNSPYEWSLPSDLLELL 218


>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 4 [Homo sapiens]
          Length = 651

 Score =  172 bits (435), Expect = 3e-42
 Identities = 131/421 (31%), Positives = 199/421 (47%), Gaps = 24/421 (5%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+     T+E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59

Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680
           L ++     WI   P     +  FP+ ++T  H G Y C+   + A  SE S+ LELV T
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119

Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
               KP +SA P+     G  + L+C   +A  GF+L KEGE E  Q L +         
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +       Y C  +    P++WS PS+ LEL++  +  KP       P+V P 
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849
             +T  C +   +  F+LYKDG  +      +    G S A+F +  V    GG Y C  
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299

Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            +   S WS PSDP+++++  +FY + +L  QPGP V  G++V L CQ       F L +
Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359

Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
           EG A  P + RS   +    A+F +  V +  +G Y C   +++     ++ S PL + V
Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419

Query: 965 T 965
           +
Sbjct: 420 S 420



 Score =  159 bits (401), Expect = 2e-38
 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+T G+ VT  C    +   + LY++        R           F
Sbjct: 27   PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83

Query: 835  LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
             I S+     G Y C Y  D +  SE SDP+ELVVT  Y KPTL AQP PVV  G +VIL
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            +C        F+L +EG       +  Q  +   + A F +  V       Y C  Y++ 
Sbjct: 144  QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S  S  L + V     KP L  +P  +V   + +TL C        ++L+K+GE 
Sbjct: 204  SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +QL G+    G     F +  +S +  G+Y  CY     SS    PS+ L++L+ G  
Sbjct: 264  DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119
              + SL  QPGP VA GEN+TL CQ +    TF+L KEGA +   + R +     Y+A+F
Sbjct: 323  YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164
             M  V    +G Y C     S P+  ++ SD LE+ V+     PS
Sbjct: 383  PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427



 Score =  154 bits (390), Expect = 4e-37
 Identities = 130/404 (32%), Positives = 182/404 (45%), Gaps = 32/404 (7%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926
            PKPTL A+PG V+  G  V LRCQG  +   + L +E         +P +          
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + ++  E +G Y C Y   T     S  S PL + VT  + KP L A+PS VV  G N
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041
            V L C   V   G+ L KEGE    Q   S      S+   F +  +S +    Y C  +
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200

Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101
               +      PS+ LELLV G+  KPSL  QPGP+VAP E +TLQC  +   + FVL K+
Sbjct: 201  DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260

Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
            G ++ L+    Q +    +A+F +  V     G Y C Y   +     S  SD L+I + 
Sbjct: 261  GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319

Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208
             +   + SLS  P      G+++TL C+       F+L  +G            Q     
Sbjct: 320  GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379

Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
             +F +  V     G Y C     + P + + PSDPLELV  +GP
Sbjct: 380  AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELV-VSGP 422



 Score =  135 bits (339), Expect = 3e-31
 Identities = 131/436 (30%), Positives = 183/436 (41%), Gaps = 32/436 (7%)

Query: 683  LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734
            LPKP + A P     +G  + LRC+G      + LY+E +         Q+L   G+   
Sbjct: 26   LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ--- 82

Query: 735  FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
            F I  +  +  G Y C   ++      SE S+PLELV+   Y KP      SPVV  G  
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 795  VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN---YSCRY 851
            V   C +      F L K+G +      + + P A  +   I SVG         Y C  
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLN-SQPHARGSSRAIFSVGPVSPSRRWWYRCYA 199

Query: 852  YDFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            YD +    WS PSD +EL+V     KP+L  QPGP+V P +++ L+C       RF L +
Sbjct: 200  YDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYK 259

Query: 909  EGAHVPLQFRSVSGNS----ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
            +G    LQ       +    A+F L  V     G Y C Y    +S+  S  S PL I +
Sbjct: 260  DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILI 318

Query: 965  TDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGSTSN 1019
               F  +  L  +P   V  G+NVTL C+       ++L KEG A         + S   
Sbjct: 319  AGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKY 378

Query: 1020 DGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAP 1079
               FP+  ++    G Y C         +   PS+ LEL+V+G    PS     GP    
Sbjct: 379  QAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTS 437

Query: 1080 G-ENMTLQCQGELPDS 1094
            G E+  L   G  P S
Sbjct: 438  GPEDQPLTPTGSDPQS 453



 Score =  125 bits (315), Expect = 2e-28
 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+     + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  +AG YRC Y  +T G S+ S  LEL   G   KP
Sbjct: 66  TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G NV + C   +    F L KEG  E              + AIFS+ 
Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P  WS PS+ L+L+V G+  KP+L+  PGPI+AP E+L L+
Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245

Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301
           C        F L +  D E+ F      +     ++ANF    +     G Y C+  ++ 
Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303

Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359
           S   S  SD L I +   F  +  L  +P   V  G+NV+L C+         L K+G  
Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363

Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418
           D P +      S      F +  VT +  G Y C+   + K  +     + +EL+V    
Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423

Query: 419 PKPS 422
             PS
Sbjct: 424 GGPS 427



 Score =  124 bits (311), Expect = 6e-28
 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G  +   + L++E        ++P   +    F
Sbjct: 24  GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C           SE S+PL+LVV G Y KPTL+A P P++  G ++
Sbjct: 84  PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296
            L+C   +    F+L +  + E    H + + ++ +    S  I   G         Y C
Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD++  Y  SL SD+L++ V     K  L  +P  +V   + ++L+C          L
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257

Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           YK GE   LQ   A         +F L  V+ S  G Y C+      +    PS     L
Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464
           +      + SLS  P      G+ +TL C+    +  F L         W  R T+Q   
Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377

Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
              +F +  V     GTY C     + P + +H S+PL+L+  GP+G
Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL+CQG      + L +E        + P     +  F
Sbjct: 24   GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++  E +G Y C Y  D+     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233
             LQC   +    F L  +GE E PQ  +       ++     +G  S S    YR  AY 
Sbjct: 142  ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201

Query: 1234 ---PDIWSEPSDPLELV 1247
               P  WS PSD LEL+
Sbjct: 202  SNSPYEWSLPSDLLELL 218


>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 1 [Homo sapiens]
          Length = 650

 Score =  172 bits (435), Expect = 3e-42
 Identities = 131/421 (31%), Positives = 199/421 (47%), Gaps = 24/421 (5%)

Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL  G     T +     PKP LWAE    +     +TL C+     T+E+ 
Sbjct: 4   ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59

Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680
           L ++     WI   P     +  FP+ ++T  H G Y C+   + A  SE S+ LELV T
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119

Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732
               KP +SA P+     G  + L+C   +A  GF+L KEGE E  Q L +         
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +       Y C  +    P++WS PS+ LEL++  +  KP       P+V P 
Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239

Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849
             +T  C +   +  F+LYKDG  +      +    G S A+F +  V    GG Y C  
Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299

Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            +   S WS PSDP+++++  +FY + +L  QPGP V  G++V L CQ       F L +
Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359

Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
           EG A  P + RS   +    A+F +  V +  +G Y C   +++     ++ S PL + V
Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419

Query: 965 T 965
           +
Sbjct: 420 S 420



 Score =  159 bits (401), Expect = 2e-38
 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+T G+ VT  C    +   + LY++        R           F
Sbjct: 27   PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83

Query: 835  LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
             I S+     G Y C Y  D +  SE SDP+ELVVT  Y KPTL AQP PVV  G +VIL
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143

Query: 894  RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
            +C        F+L +EG       +  Q  +   + A F +  V       Y C  Y++ 
Sbjct: 144  QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
                 S  S  L + V     KP L  +P  +V   + +TL C        ++L+K+GE 
Sbjct: 204  SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263

Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063
              +QL G+    G     F +  +S +  G+Y  CY     SS    PS+ L++L+ G  
Sbjct: 264  DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322

Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119
              + SL  QPGP VA GEN+TL CQ +    TF+L KEGA +   + R +     Y+A+F
Sbjct: 323  YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164
             M  V    +G Y C     S P+  ++ SD LE+ V+     PS
Sbjct: 383  PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427



 Score =  154 bits (390), Expect = 4e-37
 Identities = 130/404 (32%), Positives = 182/404 (45%), Gaps = 32/404 (7%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926
            PKPTL A+PG V+  G  V LRCQG  +   + L +E         +P +          
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + ++  E +G Y C Y   T     S  S PL + VT  + KP L A+PS VV  G N
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041
            V L C   V   G+ L KEGE    Q   S      S+   F +  +S +    Y C  +
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200

Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101
               +      PS+ LELLV G+  KPSL  QPGP+VAP E +TLQC  +   + FVL K+
Sbjct: 201  DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260

Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157
            G ++ L+    Q +    +A+F +  V     G Y C Y   +     S  SD L+I + 
Sbjct: 261  GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319

Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208
             +   + SLS  P      G+++TL C+       F+L  +G            Q     
Sbjct: 320  GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379

Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252
             +F +  V     G Y C     + P + + PSDPLELV  +GP
Sbjct: 380  AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELV-VSGP 422



 Score =  135 bits (339), Expect = 3e-31
 Identities = 131/436 (30%), Positives = 183/436 (41%), Gaps = 32/436 (7%)

Query: 683  LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734
            LPKP + A P     +G  + LRC+G      + LY+E +         Q+L   G+   
Sbjct: 26   LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ--- 82

Query: 735  FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
            F I  +  +  G Y C   ++      SE S+PLELV+   Y KP      SPVV  G  
Sbjct: 83   FPIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140

Query: 795  VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN---YSCRY 851
            V   C +      F L K+G +      + + P A  +   I SVG         Y C  
Sbjct: 141  VILQCDSQVAFDGFSLCKEGEDEHPQCLN-SQPHARGSSRAIFSVGPVSPSRRWWYRCYA 199

Query: 852  YDFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
            YD +    WS PSD +EL+V     KP+L  QPGP+V P +++ L+C       RF L +
Sbjct: 200  YDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYK 259

Query: 909  EGAHVPLQFRSVSGNS----ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
            +G    LQ       +    A+F L  V     G Y C Y    +S+  S  S PL I +
Sbjct: 260  DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILI 318

Query: 965  TDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGSTSN 1019
               F  +  L  +P   V  G+NVTL C+       ++L KEG A         + S   
Sbjct: 319  AGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKY 378

Query: 1020 DGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAP 1079
               FP+  ++    G Y C         +   PS+ LEL+V+G    PS     GP    
Sbjct: 379  QAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTS 437

Query: 1080 G-ENMTLQCQGELPDS 1094
            G E+  L   G  P S
Sbjct: 438  GPEDQPLTPTGSDPQS 453



 Score =  125 bits (315), Expect = 2e-28
 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SLG  + V     P+P LW E          +TL C+     + ++ L ++K 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  +AG YRC Y  +T G S+ S  LEL   G   KP
Sbjct: 66  TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
               Q       G NV + C   +    F L KEG  E              + AIFS+ 
Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P  WS PS+ L+L+V G+  KP+L+  PGPI+AP E+L L+
Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245

Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301
           C        F L +  D E+ F      +     ++ANF    +     G Y C+  ++ 
Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303

Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359
           S   S  SD L I +   F  +  L  +P   V  G+NV+L C+         L K+G  
Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363

Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418
           D P +      S      F +  VT +  G Y C+   + K  +     + +EL+V    
Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423

Query: 419 PKPS 422
             PS
Sbjct: 424 GGPS 427



 Score =  124 bits (311), Expect = 6e-28
 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%)

Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184
           G LPKP  W +  +    G  V + C G  +   + L++E        ++P   +    F
Sbjct: 24  GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244
            I ++T E  G Y C           SE S+PL+LVV G Y KPTL+A P P++  G ++
Sbjct: 84  PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296
            L+C   +    F+L +  + E    H + + ++ +    S  I   G         Y C
Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197

Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354
           + YD++  Y  SL SD+L++ V     K  L  +P  +V   + ++L+C          L
Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257

Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412
           YK GE   LQ   A         +F L  V+ S  G Y C+      +    PS     L
Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317

Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464
           +      + SLS  P      G+ +TL C+    +  F L         W  R T+Q   
Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377

Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509
              +F +  V     GTY C     + P + +H S+PL+L+  GP+G
Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424



 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL+CQG      + L +E        + P     +  F
Sbjct: 24   GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P++  E +G Y C Y  D+     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233
             LQC   +    F L  +GE E PQ  +       ++     +G  S S    YR  AY 
Sbjct: 142  ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201

Query: 1234 ---PDIWSEPSDPLELV 1247
               P  WS PSD LEL+
Sbjct: 202  SNSPYEWSLPSDLLELL 218


>gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]
          Length = 286

 Score =  146 bits (369), Expect = 1e-34
 Identities = 88/234 (37%), Positives = 122/234 (52%), Gaps = 14/234 (5%)

Query: 957  SMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGS 1016
            S+ +++      PKPWL A+P++VV  G NVTL CR P     + L K GE   +     
Sbjct: 23   SVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV 82

Query: 1017 TSNDGAFPITNISGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGP 1075
            +S    F +  ++    G Y CCY  PDW   +  QPS+ LELLVT  LP+PSL+A PGP
Sbjct: 83   SSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGP 142

Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCV 1135
            +V PG N++L+C G L + +FVL +EG   PL+ +  +   ADF +   R    G YSC 
Sbjct: 143  VVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCY 200

Query: 1136 YYLDSTPFAASNHSDSLEI-WVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLP 1188
            Y+  S P+  S  S+ L I W  + P     S+ P           +Q  GP P
Sbjct: 201  YHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPG----------MQAPGPPP 244



 Score =  124 bits (310), Expect = 8e-28
 Identities = 75/186 (40%), Positives = 99/186 (53%), Gaps = 9/186 (4%)

Query: 764 PSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRS 823
           PS  + +     +PKP+     + VVTPG  VT  C  P     F L+K G EIA     
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--L 78

Query: 824 WASPGASAAHFLIISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLA 879
           +    +  A F +  V    GG Y C Y    +   +WS+PSD +EL+VTE  P+P+L+A
Sbjct: 79  FRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVA 138

Query: 880 QPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGN 939
            PGPVV PG +V LRC G  + M F L +EG   PLQ+R  +   ADF L  +GA   G 
Sbjct: 139 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGT 196

Query: 940 YSCIYY 945
           YSC Y+
Sbjct: 197 YSCYYH 202



 Score =  105 bits (263), Expect = 2e-22
 Identities = 71/200 (35%), Positives = 100/200 (50%), Gaps = 7/200 (3%)

Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109
            I PS  + +      PKP L AQP  +V PG N+TL+C+   P   F L K G   PL  
Sbjct: 20   ITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79

Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAW 1168
            +  S   A+F++  V     GIY C Y   D  P   S  SD LE+ VT++ P+PSL A 
Sbjct: 80   RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVAL 139

Query: 1169 PSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNY 1224
            P  +   G +++L+C G L  + FVL  +G  AP Q+        DF +  +  +  G Y
Sbjct: 140  PGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTY 197

Query: 1225 SCSYRLQAYPDIWSEPSDPL 1244
            SC Y   + P + S+ S+ L
Sbjct: 198  SCYYHTPSAPYVLSQRSEVL 217



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 65/201 (32%), Positives = 101/201 (50%), Gaps = 6/201 (2%)

Query: 117 PSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQV 176
           PS  + +      PKP    Q  T   PG NV + C        F LFK G   P+ ++ 
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81

Query: 177 PTGTMAIFSIDNLTPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPG 235
            +  +A F ++ +TP   G+Y  C       P +WS+PS+ L+L+V    P+P+L A PG
Sbjct: 82  VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141

Query: 236 PIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295
           P++ PG +++LRC G +  M+F L R E +     ++ + +  A+F    L  +  G Y 
Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYS 198

Query: 296 CFYY--DASYRGSLLSDVLKI 314
           C+Y+   A Y  S  S+VL I
Sbjct: 199 CYYHTPSAPYVLSQRSEVLVI 219



 Score = 97.8 bits (242), Expect = 6e-20
 Identities = 68/190 (35%), Positives = 94/190 (49%), Gaps = 15/190 (7%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380
           PK WL A+P+ VV  G NV+LRCR P       L+K GE  PL F D +S  +   FFL 
Sbjct: 35  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 92

Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
            VT +  GIY C Y    W   +     + +EL+V ++ P+PSL A P  V   G  ++L
Sbjct: 93  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 152

Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492
           +C      + F L  E        R + Q ++   DF +  +  +  GTYSC Y   + P
Sbjct: 153 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 207

Query: 493 NIWSHRSEPL 502
            + S RSE L
Sbjct: 208 YVLSQRSEVL 217



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 16/221 (7%)

Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPT----PKPELWAETNFPLAPWKNLTLWCRSP 615
           + ++ I+  L    LC+  +     I++P     PKP L A+    + P  N+TL CR+P
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60

Query: 616 SGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSE 670
             + + F L K G    +  R  S ++ A F L  +T +  G Y C      W     S+
Sbjct: 61  QPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQ 118

Query: 671 PSEALELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727
           PS+ LEL+ T+ LP+P + A P      G  + LRC G L  M F LY+EG   P+Q   
Sbjct: 119 PSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRH 178

Query: 728 AVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768
           +    A FT+  +  +  G YSC  HT   P+  S+ SE L
Sbjct: 179 SAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 217



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 63/210 (30%), Positives = 96/210 (45%), Gaps = 7/210 (3%)

Query: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95
           P+P L  +      P  N+TL CR+P   + +F L K       +     +    F +  
Sbjct: 35  PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 93

Query: 96  LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151
           +T +  G+YRCCY    W    WS+PS VLEL    +LP+P           PG NV++ 
Sbjct: 94  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 153

Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211
           C G L+++ F+L++EG A P+ Y+      A F++  L     G Y C  H    P + S
Sbjct: 154 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 211

Query: 212 EPSNPLKLVVAGLYPKPTLTAHPGPIMAPG 241
           + S  L +   G  P+    +    + APG
Sbjct: 212 QRSEVLVISWEGEGPEARPASSAPGMQAPG 241



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 16/202 (7%)

Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256
           I  L TLW        PS  + +  A  +PKP L A P  ++ PG ++ LRC+ P     
Sbjct: 6   ILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 65

Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312
           F L +  ++    +  + + +E A FF + +     G Y C Y    +   + S   DVL
Sbjct: 66  FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 123

Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372
           ++ VT+  P+  L+A P  VV  G NVSLRC G +  +   LY++G   PLQ+    S  
Sbjct: 124 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 181

Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394
               F L  +     G YSC+Y
Sbjct: 182 PWADFTL--LGARAPGTYSCYY 201



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 9/186 (4%)

Query: 671 PSEALELVGTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727
           PS A+ +      PKP + A P      G  + LRC+       F L+K GE  P+    
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81

Query: 728 AVGREAFFTIQRMEDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWAS 786
                A F ++ +     G Y C     +  P  WS+PS+ LEL++ E  P+P       
Sbjct: 82  VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141

Query: 787 PVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN 846
           PVV PGA V+  C+   ++MSF+LY++G       R  A P A         +G    G 
Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGT 196

Query: 847 YSCRYY 852
           YSC Y+
Sbjct: 197 YSCYYH 202



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 5/92 (5%)

Query: 1161 PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQF----SEDGDFVINNV 1216
            PKP L A P+T+   G ++TL+CR P P   F L   GE AP  F    SE  +F +  V
Sbjct: 35   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 94

Query: 1217 EGKGIGNYSCSYRLQAY-PDIWSEPSDPLELV 1247
                 G Y C YR   + P +WS+PSD LEL+
Sbjct: 95   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELL 126



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERE----TFQKFSVN-GDFIISN 473
           PKP L A P+TV   G  +TL+CR   P   F L ++  E     F+  S    +F +  
Sbjct: 35  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGL-FKPGEIAPLLFRDVSSELAEFFLEE 93

Query: 474 VDGKGTGTYSCSY-RVETHPNIWSHRSEPLKLM 505
           V     G Y C Y R +  P +WS  S+ L+L+
Sbjct: 94  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELL 126


>gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens]
          Length = 267

 Score =  144 bits (363), Expect = 6e-34
 Identities = 80/199 (40%), Positives = 111/199 (55%), Gaps = 3/199 (1%)

Query: 957  SMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGS 1016
            S+ +++      PKPWL A+P++VV  G NVTL CR P     + L K GE   +     
Sbjct: 23   SVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV 82

Query: 1017 TSNDGAFPITNISGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGP 1075
            +S    F +  ++    G Y CCY  PDW   +  QPS+ LELLVT  LP+PSL+A PGP
Sbjct: 83   SSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGP 142

Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCV 1135
            +V PG N++L+C G L + +FVL +EG   PL+ +  +   ADF +   R    G YSC 
Sbjct: 143  VVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCY 200

Query: 1136 YYLDSTPFAASNHSDSLEI 1154
            Y+  S P+  S  S+ L I
Sbjct: 201  YHTPSAPYVLSQRSEVLVI 219



 Score =  124 bits (310), Expect = 8e-28
 Identities = 75/186 (40%), Positives = 99/186 (53%), Gaps = 9/186 (4%)

Query: 764 PSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRS 823
           PS  + +     +PKP+     + VVTPG  VT  C  P     F L+K G EIA     
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--L 78

Query: 824 WASPGASAAHFLIISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLA 879
           +    +  A F +  V    GG Y C Y    +   +WS+PSD +EL+VTE  P+P+L+A
Sbjct: 79  FRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVA 138

Query: 880 QPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGN 939
            PGPVV PG +V LRC G  + M F L +EG   PLQ+R  +   ADF L  +GA   G 
Sbjct: 139 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGT 196

Query: 940 YSCIYY 945
           YSC Y+
Sbjct: 197 YSCYYH 202



 Score =  123 bits (308), Expect = 1e-27
 Identities = 82/244 (33%), Positives = 124/244 (50%), Gaps = 8/244 (3%)

Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109
            I PS  + +      PKP L AQP  +V PG N+TL+C+   P   F L K G   PL  
Sbjct: 20   ITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79

Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAW 1168
            +  S   A+F++  V     GIY C Y   D  P   S  SD LE+ VT++ P+PSL A 
Sbjct: 80   RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVAL 139

Query: 1169 PSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNY 1224
            P  +   G +++L+C G L  + FVL  +G  AP Q+        DF +  +  +  G Y
Sbjct: 140  PGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTY 197

Query: 1225 SCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWK 1284
            SC Y   + P + S+ S+ L ++      + + T GN+VR  L  +V+++LG ++  +W+
Sbjct: 198  SCYYHTPSAPYVLSQRSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWR 256

Query: 1285 KWPR 1288
               R
Sbjct: 257  SQNR 260



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380
           PK WL A+P+ VV  G NV+LRCR P       L+K GE  PL F D +S  +   FFL 
Sbjct: 35  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 92

Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
            VT +  GIY C Y    W   +     + +EL+V ++ P+PSL A P  V   G  ++L
Sbjct: 93  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 152

Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492
           +C      + F L  E        R + Q ++   DF +  +  +  GTYSC Y   + P
Sbjct: 153 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 207

Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542
            + S RSE L +       + +Y     +RL L   ++  L  ++   W+
Sbjct: 208 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 256



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 65/201 (32%), Positives = 101/201 (50%), Gaps = 6/201 (2%)

Query: 117 PSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQV 176
           PS  + +      PKP    Q  T   PG NV + C        F LFK G   P+ ++ 
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81

Query: 177 PTGTMAIFSIDNLTPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPG 235
            +  +A F ++ +TP   G+Y  C       P +WS+PS+ L+L+V    P+P+L A PG
Sbjct: 82  VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141

Query: 236 PIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295
           P++ PG +++LRC G +  M+F L R E +     ++ + +  A+F    L  +  G Y 
Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYS 198

Query: 296 CFYY--DASYRGSLLSDVLKI 314
           C+Y+   A Y  S  S+VL I
Sbjct: 199 CYYHTPSAPYVLSQRSEVLVI 219



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 16/221 (7%)

Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPT----PKPELWAETNFPLAPWKNLTLWCRSP 615
           + ++ I+  L    LC+  +     I++P     PKP L A+    + P  N+TL CR+P
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60

Query: 616 SGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSE 670
             + + F L K G    +  R  S ++ A F L  +T +  G Y C      W     S+
Sbjct: 61  QPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQ 118

Query: 671 PSEALELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727
           PS+ LEL+ T+ LP+P + A P      G  + LRC G L  M F LY+EG   P+Q   
Sbjct: 119 PSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRH 178

Query: 728 AVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768
           +    A FT+  +  +  G YSC  HT   P+  S+ SE L
Sbjct: 179 SAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 217



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 16/202 (7%)

Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256
           I  L TLW        PS  + +  A  +PKP L A P  ++ PG ++ LRC+ P     
Sbjct: 6   ILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 65

Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312
           F L +  ++    +  + + +E A FF + +     G Y C Y    +   + S   DVL
Sbjct: 66  FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 123

Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372
           ++ VT+  P+  L+A P  VV  G NVSLRC G +  +   LY++G   PLQ+    S  
Sbjct: 124 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 181

Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394
               F L  +     G YSC+Y
Sbjct: 182 PWADFTL--LGARAPGTYSCYY 201



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%)

Query: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95
           P+P L  +      P  N+TL CR+P   + +F L K       +     +    F +  
Sbjct: 35  PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 93

Query: 96  LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151
           +T +  G+YRCCY    W    WS+PS VLEL    +LP+P           PG NV++ 
Sbjct: 94  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 153

Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211
           C G L+++ F+L++EG A P+ Y+      A F++  L     G Y C  H    P + S
Sbjct: 154 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 211

Query: 212 EPSNPL 217
           + S  L
Sbjct: 212 QRSEVL 217



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 9/186 (4%)

Query: 671 PSEALELVGTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727
           PS A+ +      PKP + A P      G  + LRC+       F L+K GE  P+    
Sbjct: 22  PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81

Query: 728 AVGREAFFTIQRMEDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWAS 786
                A F ++ +     G Y C     +  P  WS+PS+ LEL++ E  P+P       
Sbjct: 82  VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141

Query: 787 PVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN 846
           PVV PGA V+  C+   ++MSF+LY++G       R  A P A         +G    G 
Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGT 196

Query: 847 YSCRYY 852
           YSC Y+
Sbjct: 197 YSCYYH 202


>gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens]
          Length = 263

 Score =  144 bits (362), Expect = 7e-34
 Identities = 79/187 (42%), Positives = 106/187 (56%), Gaps = 3/187 (1%)

Query: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028
            PKPWL A+P++VV  G NVTL CR P     + L K GE   +     +S    F +  +
Sbjct: 31   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90

Query: 1029 SGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087
            +    G Y CCY  PDW   +  QPS+ LELLVT  LP+PSL+A PGP+V PG N++L+C
Sbjct: 91   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150

Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147
             G L + +FVL +EG   PL+ +  +   ADF +   R    G YSC Y+  S P+  S 
Sbjct: 151  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPSAPYVLSQ 208

Query: 1148 HSDSLEI 1154
             S+ L I
Sbjct: 209  RSEVLVI 215



 Score =  123 bits (309), Expect = 1e-27
 Identities = 73/174 (41%), Positives = 95/174 (54%), Gaps = 9/174 (5%)

Query: 776 YPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFL 835
           +PKP+     + VVTPG  VT  C  P     F L+K G EIA     +    +  A F 
Sbjct: 30  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--LFRDVSSELAEFF 86

Query: 836 IISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891
           +  V    GG Y C Y    +   +WS+PSD +EL+VTE  P+P+L+A PGPVV PG +V
Sbjct: 87  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 146

Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945
            LRC G  + M F L +EG   PLQ+R  +   ADF L  +GA   G YSC Y+
Sbjct: 147 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 198



 Score =  122 bits (306), Expect = 2e-27
 Identities = 79/229 (34%), Positives = 119/229 (51%), Gaps = 8/229 (3%)

Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAV 1124
            PKP L AQP  +V PG N+TL+C+   P   F L K G   PL  +  S   A+F++  V
Sbjct: 31   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90

Query: 1125 RGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183
                 GIY C Y   D  P   S  SD LE+ VT++ P+PSL A P  +   G +++L+C
Sbjct: 91   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150

Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239
             G L  + FVL  +G  AP Q+        DF +  +  +  G YSC Y   + P + S+
Sbjct: 151  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQ 208

Query: 1240 PSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWKKWPR 1288
             S+ L ++      + + T GN+VR  L  +V+++LG ++  +W+   R
Sbjct: 209  RSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 256



 Score =  103 bits (258), Expect = 8e-22
 Identities = 68/187 (36%), Positives = 88/187 (47%), Gaps = 3/187 (1%)

Query: 871  FYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLH 930
            ++PKP L AQP  VV PG +V LRC+      RF L + G   PL FR VS   A+F L 
Sbjct: 29   YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 88

Query: 931  TVGAEDSGNYSCIYYETTMS-NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
             V     G Y C Y          S  S  L + VT+  P+P L A P  VV  G NV+L
Sbjct: 89   EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 148

Query: 990  WCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIK 1049
             C G +  + ++L++EG A  +Q   S      F  T +   + G YSC YH      + 
Sbjct: 149  RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADF--TLLGARAPGTYSCYYHTPSAPYVL 206

Query: 1050 IQPSNTL 1056
             Q S  L
Sbjct: 207  SQRSEVL 213



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380
           PK WL A+P+ VV  G NV+LRCR P       L+K GE  PL F D +S  +   FFL 
Sbjct: 31  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 88

Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
            VT +  GIY C Y    W   +     + +EL+V ++ P+PSL A P  V   G  ++L
Sbjct: 89  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 148

Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492
           +C      + F L  E        R + Q ++   DF +  +  +  GTYSC Y   + P
Sbjct: 149 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 203

Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542
            + S RSE L +       + +Y     +RL L   ++  L  ++   W+
Sbjct: 204 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 252



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 6/188 (3%)

Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNL 189
           PKP    Q  T   PG NV + C        F LFK G   P+ ++  +  +A F ++ +
Sbjct: 31  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90

Query: 190 TPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248
           TP   G+Y  C       P +WS+PS+ L+L+V    P+P+L A PGP++ PG +++LRC
Sbjct: 91  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150

Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYY--DASYRGS 306
            G +  M+F L R E +     ++ + +  A+F    L  +  G Y C+Y+   A Y  S
Sbjct: 151 AGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 207

Query: 307 LLSDVLKI 314
             S+VL I
Sbjct: 208 QRSEVLVI 215



 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 70/217 (32%), Positives = 102/217 (47%), Gaps = 12/217 (5%)

Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGST 619
           + ++ I+  L    LC+  +          PKP L A+    + P  N+TL CR+P  + 
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 60

Query: 620 KEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSEPSEA 674
           + F L K G    +  R  S ++ A F L  +T +  G Y C      W     S+PS+ 
Sbjct: 61  R-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDV 118

Query: 675 LELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR 731
           LEL+ T+ LP+P + A P      G  + LRC G L  M F LY+EG   P+Q   +   
Sbjct: 119 LELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP 178

Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768
            A FT+  +  +  G YSC  HT   P+  S+ SE L
Sbjct: 179 WADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 213



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%)

Query: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95
           P+P L  +      P  N+TL CR+P   + +F L K       +     +    F +  
Sbjct: 31  PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 89

Query: 96  LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151
           +T +  G+YRCCY    W    WS+PS VLEL    +LP+P           PG NV++ 
Sbjct: 90  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 149

Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211
           C G L+++ F+L++EG A P+ Y+      A F++  L     G Y C  H    P + S
Sbjct: 150 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 207

Query: 212 EPSNPL 217
           + S  L
Sbjct: 208 QRSEVL 213



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 65/202 (32%), Positives = 94/202 (46%), Gaps = 20/202 (9%)

Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256
           I  L TLW        PS P     A  +PKP L A P  ++ PG ++ LRC+ P     
Sbjct: 6   ILQLLTLWPLCHTDITPSVP----PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 61

Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312
           F L +  ++    +  + + +E A FF + +     G Y C Y    +   + S   DVL
Sbjct: 62  FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 119

Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372
           ++ VT+  P+  L+A P  VV  G NVSLRC G +  +   LY++G   PLQ+    S  
Sbjct: 120 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 177

Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394
               F L  +     G YSC+Y
Sbjct: 178 PWADFTL--LGARAPGTYSCYY 197



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 55/173 (31%), Positives = 78/173 (45%), Gaps = 9/173 (5%)

Query: 684 PKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRM 740
           PKP + A P      G  + LRC+       F L+K GE  P+         A F ++ +
Sbjct: 31  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90

Query: 741 EDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNC 799
                G Y C     +  P  WS+PS+ LEL++ E  P+P       PVV PGA V+  C
Sbjct: 91  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150

Query: 800 STPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852
           +   ++MSF+LY++G       R  A P A         +G    G YSC Y+
Sbjct: 151 AGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGTYSCYYH 198


>gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens]
          Length = 252

 Score =  144 bits (362), Expect = 7e-34
 Identities = 79/187 (42%), Positives = 106/187 (56%), Gaps = 3/187 (1%)

Query: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028
            PKPWL A+P++VV  G NVTL CR P     + L K GE   +     +S    F +  +
Sbjct: 20   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79

Query: 1029 SGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087
            +    G Y CCY  PDW   +  QPS+ LELLVT  LP+PSL+A PGP+V PG N++L+C
Sbjct: 80   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139

Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147
             G L + +FVL +EG   PL+ +  +   ADF +   R    G YSC Y+  S P+  S 
Sbjct: 140  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPSAPYVLSQ 197

Query: 1148 HSDSLEI 1154
             S+ L I
Sbjct: 198  RSEVLVI 204



 Score =  123 bits (309), Expect = 1e-27
 Identities = 73/174 (41%), Positives = 95/174 (54%), Gaps = 9/174 (5%)

Query: 776 YPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFL 835
           +PKP+     + VVTPG  VT  C  P     F L+K G EIA     +    +  A F 
Sbjct: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--LFRDVSSELAEFF 75

Query: 836 IISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891
           +  V    GG Y C Y    +   +WS+PSD +EL+VTE  P+P+L+A PGPVV PG +V
Sbjct: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135

Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945
            LRC G  + M F L +EG   PLQ+R  +   ADF L  +GA   G YSC Y+
Sbjct: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 187



 Score =  122 bits (306), Expect = 2e-27
 Identities = 79/229 (34%), Positives = 119/229 (51%), Gaps = 8/229 (3%)

Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAV 1124
            PKP L AQP  +V PG N+TL+C+   P   F L K G   PL  +  S   A+F++  V
Sbjct: 20   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79

Query: 1125 RGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183
                 GIY C Y   D  P   S  SD LE+ VT++ P+PSL A P  +   G +++L+C
Sbjct: 80   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139

Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239
             G L  + FVL  +G  AP Q+        DF +  +  +  G YSC Y   + P + S+
Sbjct: 140  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQ 197

Query: 1240 PSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWKKWPR 1288
             S+ L ++      + + T GN+VR  L  +V+++LG ++  +W+   R
Sbjct: 198  RSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 245



 Score =  103 bits (258), Expect = 8e-22
 Identities = 68/187 (36%), Positives = 88/187 (47%), Gaps = 3/187 (1%)

Query: 871  FYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLH 930
            ++PKP L AQP  VV PG +V LRC+      RF L + G   PL FR VS   A+F L 
Sbjct: 18   YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 77

Query: 931  TVGAEDSGNYSCIYYETTMS-NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
             V     G Y C Y          S  S  L + VT+  P+P L A P  VV  G NV+L
Sbjct: 78   EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137

Query: 990  WCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIK 1049
             C G +  + ++L++EG A  +Q   S      F  T +   + G YSC YH      + 
Sbjct: 138  RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADF--TLLGARAPGTYSCYYHTPSAPYVL 195

Query: 1050 IQPSNTL 1056
             Q S  L
Sbjct: 196  SQRSEVL 202



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%)

Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380
           PK WL A+P+ VV  G NV+LRCR P       L+K GE  PL F D +S  +   FFL 
Sbjct: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 77

Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
            VT +  GIY C Y    W   +     + +EL+V ++ P+PSL A P  V   G  ++L
Sbjct: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137

Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492
           +C      + F L  E        R + Q ++   DF +  +  +  GTYSC Y   + P
Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 192

Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542
            + S RSE L +       + +Y     +RL L   ++  L  ++   W+
Sbjct: 193 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 241



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 6/188 (3%)

Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNL 189
           PKP    Q  T   PG NV + C        F LFK G   P+ ++  +  +A F ++ +
Sbjct: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79

Query: 190 TPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248
           TP   G+Y  C       P +WS+PS+ L+L+V    P+P+L A PGP++ PG +++LRC
Sbjct: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139

Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYY--DASYRGS 306
            G +  M+F L R E +     ++ + +  A+F    L  +  G Y C+Y+   A Y  S
Sbjct: 140 AGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196

Query: 307 LLSDVLKI 314
             S+VL I
Sbjct: 197 QRSEVLVI 204



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%)

Query: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95
           P+P L  +      P  N+TL CR+P   + +F L K       +     +    F +  
Sbjct: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 78

Query: 96  LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151
           +T +  G+YRCCY    W    WS+PS VLEL    +LP+P           PG NV++ 
Sbjct: 79  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 138

Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211
           C G L+++ F+L++EG A P+ Y+      A F++  L     G Y C  H    P + S
Sbjct: 139 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196

Query: 212 EPSNPL 217
           + S  L
Sbjct: 197 QRSEVL 202



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 66/187 (35%), Positives = 92/187 (49%), Gaps = 12/187 (6%)

Query: 590 PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLG 648
           PKP L A+    + P  N+TL CR+P  + + F L K G    +  R  S ++ A F L 
Sbjct: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLE 77

Query: 649 ALTQSHTGSYHC----HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQELQL 701
            +T +  G Y C      W     S+PS+ LEL+ T+ LP+P + A P      G  + L
Sbjct: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137

Query: 702 RCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKW 761
           RC G L  M F LY+EG   P+Q   +    A FT+  +  +  G YSC  HT   P+  
Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVL 195

Query: 762 SEPSEPL 768
           S+ SE L
Sbjct: 196 SQRSEVL 202



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 10/177 (5%)

Query: 222 AGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNE-AN 280
           A  +PKP L A P  ++ PG ++ LRC+ P     F L +  ++    +  + + +E A 
Sbjct: 16  ASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF--RDVSSELAE 73

Query: 281 FFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVLKIWVTDTFPKTWLLARPSAVVQMGQ 337
           FF + +     G Y C Y    +   + S   DVL++ VT+  P+  L+A P  VV  G 
Sbjct: 74  FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133

Query: 338 NVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHY 394
           NVSLRC G +  +   LY++G   PLQ+    S      F L  +     G YSC+Y
Sbjct: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQPWADFTL--LGARAPGTYSCYY 186



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 55/173 (31%), Positives = 78/173 (45%), Gaps = 9/173 (5%)

Query: 684 PKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRM 740
           PKP + A P      G  + LRC+       F L+K GE  P+         A F ++ +
Sbjct: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79

Query: 741 EDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNC 799
                G Y C     +  P  WS+PS+ LEL++ E  P+P       PVV PGA V+  C
Sbjct: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139

Query: 800 STPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852
           +   ++MSF+LY++G       R  A P A         +G    G YSC Y+
Sbjct: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGTYSCYYH 187


>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
            member 5 isoform 3 [Homo sapiens]
          Length = 491

 Score =  140 bits (352), Expect = 1e-32
 Identities = 112/325 (34%), Positives = 153/325 (47%), Gaps = 31/325 (9%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926
            PKPTL A+P  V+  GK V L CQG  +   + L +EG         PL+     G  A 
Sbjct: 27   PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82

Query: 927  FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986
            F + +   + +G Y C YYET      S  S PL +  T    KP L     SVV  G +
Sbjct: 83   FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGVSRKPSLLIPQGSVVARGGS 139

Query: 987  VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCC--- 1039
            +TL CR  V    ++L+KEGE   +Q  G     G     F +  +S +  G+Y C    
Sbjct: 140  LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 199

Query: 1040 -YHPDWTSSIKIQPSNTLELLVTGLLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFV 1097
               P W++     PS+ L++L+ GL+P  P+L  QPGP VA GEN+TL CQ      TF 
Sbjct: 200  NLSPRWSA-----PSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFF 254

Query: 1098 LLKEGAQEP----LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLE 1153
            L KEGA  P      + +   ++A+F M  V     G Y C   + S P+  S+ S   E
Sbjct: 255  LTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQE 314

Query: 1154 IWVTDKPPKPSLSAWPSTMFKLGKD 1178
            + V+     PSLS   ST    G +
Sbjct: 315  LVVSGPSGDPSLSPTGSTPTPAGPE 339



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/301 (34%), Positives = 149/301 (49%), Gaps = 20/301 (6%)

Query: 967  TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE--ATSMQLWGSTSNDGAFP 1024
            T PKP L+AEP+SV+  G+ VTLWC+GP+    Y L KEG   A   Q          F 
Sbjct: 25   TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84

Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084
            I +    S GRY C Y    T +   +PS+ LEL+ TG+  KPSLL   G +VA G ++T
Sbjct: 85   IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLT 141

Query: 1085 LQCQGELPDSTFVLLKEGAQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDS 1140
            LQC+ ++    FVL KEG  + ++   QQ  +G  +A+F +  V     G Y C    + 
Sbjct: 142  LQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNL 201

Query: 1141 TPFAASNHSDSLEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE 1199
            +P   S  SD L+I +    P  P+LS  P      G+++TL C+       F L  +G 
Sbjct: 202  SP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGA 260

Query: 1200 EAP--------QQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAG 1251
              P        Q +    +F ++ V     G Y C   +++YP + S PS P ELV  +G
Sbjct: 261  AHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSG 319

Query: 1252 P 1252
            P
Sbjct: 320  P 320



 Score =  134 bits (338), Expect = 4e-31
 Identities = 112/336 (33%), Positives = 154/336 (45%), Gaps = 30/336 (8%)

Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620
           M   ++ L+C GL  G     T +   T PKP LWAE    +A  K +TLWC+ P   T+
Sbjct: 1   MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56

Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678
           E+ L K+G  W   R  P     +A F + +      G Y C+       SEPS+ LELV
Sbjct: 57  EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 679 GTDILPKP---VISASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGR 731
            T +  KP   +   S   RG  L L+C+  +    F LYKEGE + VQ  G    A   
Sbjct: 117 ATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLS 176

Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPK-PFFKTWASPVVT 790
           +A FT+  +     G Y C       P +WS PS+PL+++I  + P  P       P V 
Sbjct: 177 QANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVA 235

Query: 791 PGARVTFNCSTPHQHMSFILYKDGSE-----IASSDRSWASPGASAAHFLIISVGIGDGG 845
            G  VT  C + HQ  +F L K+G+      + S  +S+       A F +  V    GG
Sbjct: 236 SGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSY----RHQAEFSMSPVTSAQGG 291

Query: 846 NYSC----RYYDFSIWSEPSDPVELVVTEFYPKPTL 877
            Y C    R Y + + S PS P ELVV+     P+L
Sbjct: 292 TYRCYSAIRSYPY-LLSSPSYPQELVVSGPSGDPSL 326



 Score =  120 bits (302), Expect = 7e-27
 Identities = 108/338 (31%), Positives = 148/338 (43%), Gaps = 29/338 (8%)

Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733
           LPKP + A P     RG+ + L C+G L    + L KEG       Q P++     G +A
Sbjct: 26  LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81

Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793
            F I        G Y C   T   P  WSEPS+PLELV   +  KP        VV  G 
Sbjct: 82  KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGG 138

Query: 794 RVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852
            +T  C +   +  F+LYK+G  ++          G S A+F +  V    GG Y C Y 
Sbjct: 139 SLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YG 197

Query: 853 DFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908
             ++   WS PSDP+++++    P  P L  QPGP V  G++V L CQ   Q   F L +
Sbjct: 198 AHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTK 257

Query: 909 EG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964
           EG AH PL  +S      + A+F +  V +   G Y C     +     S  S P  + V
Sbjct: 258 EGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVV 317

Query: 965 TDTFPKPWLFAEPSSVVPMG---QNVTLWCRGPVHGVG 999
           +     P L    S+  P G   Q +T     P  G+G
Sbjct: 318 SGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLG 355



 Score =  115 bits (289), Expect = 2e-25
 Identities = 96/309 (31%), Positives = 142/309 (45%), Gaps = 24/309 (7%)

Query: 12  MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68
           M  T +VL+ C+ +S+G  + V     P+P LW E     A  + +TLWC+ P       
Sbjct: 1   MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59

Query: 69  LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124
           L   DK  + W R    P     +  F I +    +AG YRC Y    GWS+PS  LEL 
Sbjct: 60  L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116

Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVD---YQVPTG-T 180
           A G   KP   I   +    G ++ + C   +   +F+L+KEG  + V     Q   G +
Sbjct: 117 ATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLS 176

Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPK-PTLTAHPGPIMA 239
            A F++  ++    G Y C     + P  WS PS+PL +++AGL P  P L+  PGP +A
Sbjct: 177 QANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVA 235

Query: 240 PGESLNLRCQGPIYGMTFALMRVEDLE-----KSFYHKKTIKNEANFFFQSLKIQDTGHY 294
            GE++ L CQ      TF L +          KS Y  ++ +++A F    +     G Y
Sbjct: 236 SGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY--QSYRHQAEFSMSPVTSAQGGTY 293

Query: 295 LCFYYDASY 303
            C+    SY
Sbjct: 294 RCYSAIRSY 302



 Score =  111 bits (278), Expect = 4e-24
 Identities = 100/304 (32%), Positives = 131/304 (43%), Gaps = 15/304 (4%)

Query: 777  PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
            PKP    WA P  V+  G  VT  C  P +   + L K+G   A   ++   PGA A  F
Sbjct: 27   PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83

Query: 835  LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894
             I S      G Y C Y   + WSEPSDP+ELV T    KP+LL   G VV  G S+ L+
Sbjct: 84   HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLTLQ 143

Query: 895  CQGTFQGMRFALLQEGAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950
            C+       F L +EG H  +Q          + A+F L  V     G Y C Y    +S
Sbjct: 144  CRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLS 202

Query: 951  NRGSYLSMPLMIWVTDTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA- 1008
             R S  S PL I +    P  P L  +P   V  G+NVTL C+       + L KEG A 
Sbjct: 203  PRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAH 262

Query: 1009 ---TSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLP 1065
                    + S  +   F ++ ++    G Y C         +   PS   EL+V+G   
Sbjct: 263  PPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 322

Query: 1066 KPSL 1069
             PSL
Sbjct: 323  DPSL 326



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 91/315 (28%), Positives = 131/315 (41%), Gaps = 30/315 (9%)

Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIY---------GMTFALMRVEDLE 266
           P   V AG  PKPTL A P  ++A G+ + L CQGP+          G+ +A  R   LE
Sbjct: 17  PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE 76

Query: 267 KSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLL 326
                      +A F   S      G Y C YY+     S  SD L++  T    K  LL
Sbjct: 77  PGA--------KAKFHIPSTVYDSAGRYRC-YYETPAGWSEPSDPLELVATGVSRKPSLL 127

Query: 327 ARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ--FLDATSIDDNTSFFLNNVTY 384
               +VV  G +++L+CR  V      LYK+GE   +Q       +     +F L  V+ 
Sbjct: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187

Query: 385 SDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVS 444
           S  G Y C+           PS     L+    P  P+LS  P      G+ +TL C+  
Sbjct: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247

Query: 445 HPVLEFSLEWEE--------RETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWS 496
           H +  F L  E         +  +Q +    +F +S V     GTY C   + ++P + S
Sbjct: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307

Query: 497 HRSEPLKLM--GPAG 509
             S P +L+  GP+G
Sbjct: 308 SPSYPQELVVSGPSG 322



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 68/196 (34%), Positives = 94/196 (47%), Gaps = 14/196 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119
            G LPKP+L A+P  ++A G+ +TL CQG L    + L KEG     ++Q P   G +A F
Sbjct: 24   GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             +P+   + +G Y C Y    TP   S  SD LE+  T    KPSL     ++   G  +
Sbjct: 84   HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSL 140

Query: 1180 TLQCRGPLPGVEFVLEHDGE--------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQ 1231
            TLQCR  +    FVL  +GE        + PQ      +F +  V     G Y C Y   
Sbjct: 141  TLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAH 199

Query: 1232 AYPDIWSEPSDPLELV 1247
                 WS PSDPL+++
Sbjct: 200  NLSPRWSAPSDPLDIL 215



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 68/207 (32%), Positives = 93/207 (44%), Gaps = 14/207 (6%)

Query: 37  QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92
           +P L I      A   ++TL CRS       F+L K    D  Q +  +P     Q +F 
Sbjct: 123 KPSLLIPQGSVVARGGSLTLQCRSDVGYDI-FVLYKEGEHDLVQGSGQQPQAGLSQANFT 181

Query: 93  IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLPK-PIFWIQAETPALPGCNVN 149
           +G ++ S+ G YRC   +     WS PS  L++   G +P  P   +Q       G NV 
Sbjct: 182 LGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVT 241

Query: 150 ILCHGWLQDLVFMLFKEGYAEPV-----DYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204
           +LC  W Q   F L KEG A P       YQ      A FS+  +T    G Y C + I+
Sbjct: 242 LLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQ-SYRHQAEFSMSPVTSAQGGTYRCYSAIR 300

Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLT 231
             P L S PS P +LVV+G    P+L+
Sbjct: 301 SYPYLLSSPSYPQELVVSGPSGDPSLS 327


>gi|46488946 killer cell immunoglobulin-like receptor, three domains,
            long cytoplasmic tail, 3 [Homo sapiens]
          Length = 410

 Score =  130 bits (326), Expect = 1e-29
 Identities = 101/330 (30%), Positives = 156/330 (47%), Gaps = 24/330 (7%)

Query: 970  KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029
            KP+L A P +VV  GQ+VTL CR  +    + L KE      +L+     + +F +  ++
Sbjct: 28   KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRN-SFLMGPVT 86

Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089
                G Y CC     + +    PSN + ++VTG+  KPSLLA PGP+V  GE + LQC  
Sbjct: 87   PAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWS 146

Query: 1090 ELPDSTFVLLKEG-AQEPLE---QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145
            ++    F+L +EG  ++PL    Q   +G + ++ M  +    +G Y C   +   P+  
Sbjct: 147  DVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYEL 206

Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQF 1205
            S  SD L+I V     KPSLSA P    + G+++TL C        + L  + E    + 
Sbjct: 207  SAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRL 266

Query: 1206 SE----DGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTV 1259
            +     +G F  N   G     GNY C    +A P  WS+PSDPL       PV+     
Sbjct: 267  TAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPL-------PVS---VT 316

Query: 1260 GNIVRSSLIV---VVVVALGVVLAIEWKKW 1286
            GN     +++   VV++   ++L     +W
Sbjct: 317  GNSRHLHVLIGTSVVIIPFAILLFFLLHRW 346



 Score =  103 bits (256), Expect = 1e-21
 Identities = 93/296 (31%), Positives = 131/296 (44%), Gaps = 17/296 (5%)

Query: 778  KPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYK-DGSEIASS-DRSWASPGASAAHFL 835
            KPF   W   VV+ G  VT  C +      F L K DG  +    +R + +       FL
Sbjct: 28   KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRNS------FL 81

Query: 836  IISVGIGDGGNYSC---RYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVI 892
            +  V     G Y C     +  + WS PS+PV ++VT  + KP+LLA PGP+V  G++VI
Sbjct: 82   MGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVI 141

Query: 893  LRCQGTFQGMRFALLQEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSCIYYETT 948
            L+C    +  RF L +EG    PL+       +G+  ++ +  +    +G Y C    T 
Sbjct: 142  LQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTH 201

Query: 949  MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008
            +    S  S PL I V   + KP L A+P   V  G+NVTL C        Y L +E EA
Sbjct: 202  LPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEA 261

Query: 1009 TSMQLWGSTSNDGAFPITNISG--TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG 1062
              ++L      +G F      G  T  G Y C             PS+ L + VTG
Sbjct: 262  GELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317



 Score =  100 bits (249), Expect = 9e-21
 Identities = 68/204 (33%), Positives = 99/204 (48%), Gaps = 9/204 (4%)

Query: 52  ENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCY--- 108
           +++TL CRS  R+      L  +  M      ++ F+ SFL+G +T ++AG YRCC    
Sbjct: 43  QHVTLQCRS--RLGFNEFSLSKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHP 100

Query: 109 WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGY 168
              TGWS PS  + +   G   KP            G  V + C   ++   F+L +EG 
Sbjct: 101 HSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGI 160

Query: 169 AEP----VDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGL 224
            E     V      G+   +S+  +TP   G Y C   +  LP   S PS+PL +VV GL
Sbjct: 161 TEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGL 220

Query: 225 YPKPTLTAHPGPIMAPGESLNLRC 248
           Y KP+L+A PGP +  GE++ L C
Sbjct: 221 YGKPSLSAQPGPTVQAGENVTLSC 244



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 86/297 (28%), Positives = 132/297 (44%), Gaps = 26/297 (8%)

Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGAL 650
           KP L A     ++  +++TL CRS  G   EF L K+  G       +   R +F +G +
Sbjct: 28  KPFLSAWPGTVVSEGQHVTLQCRSRLGFN-EFSLSKED-GMPVPELYNRIFRNSFLMGPV 85

Query: 651 TQSHTGSYHC---HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQELQLRCK 704
           T +H G+Y C   H       S PS  + ++ T +  KP + A P      G+ + L+C 
Sbjct: 86  TPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCW 145

Query: 705 GWLAGMGFALYKEGEQEP----VQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFK 760
             +    F L++EG  E     V QL   G +  +++  M     G Y C       P++
Sbjct: 146 SDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYE 205

Query: 761 WSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASS 820
            S PS+PL++V+  +Y KP       P V  G  VT +CS+      F +Y    E  + 
Sbjct: 206 LSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSS---RSLFDIYHLSREAEAG 262

Query: 821 DRSWAS----PGASAAHFLIISVGIGDGGNYSCRYYDF----SIWSEPSDPVELVVT 869
           +    +     G   A+F +  V    GGNY C +  F      WS+PSDP+ + VT
Sbjct: 263 ELRLTAVLRVNGTFQANFPLGPV--THGGNYRC-FGSFRALPHAWSDPSDPLPVSVT 316



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 73/230 (31%), Positives = 99/230 (43%), Gaps = 10/230 (4%)

Query: 123 LEAP----GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT 178
           LE P    G   KP       T    G +V + C   L    F L KE    PV      
Sbjct: 16  LEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKED-GMPVPELYNR 74

Query: 179 GTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIM 238
                F +  +TP   G Y C +     PT WS PSNP+ ++V G++ KP+L AHPGP++
Sbjct: 75  IFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLV 134

Query: 239 APGESLNLRCQGPIYGMTFALMR---VEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295
             GE++ L+C   +    F L R    ED  +         ++ N+    +     G Y 
Sbjct: 135 KSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYR 194

Query: 296 CF--YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC 343
           CF       Y  S  SD L I V   + K  L A+P   VQ G+NV+L C
Sbjct: 195 CFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSC 244



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 86/325 (26%), Positives = 141/325 (43%), Gaps = 16/325 (4%)

Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286
           KP L+A PG +++ G+ + L+C+  +    F+L + + +     + +  +N  +F    +
Sbjct: 28  KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRN--SFLMGPV 85

Query: 287 KIQDTGHY-LCFYYDASYRG-SLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344
                G Y  C  +  S  G S  S+ + I VT    K  LLA P  +V+ G+ V L+C 
Sbjct: 86  TPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCW 145

Query: 345 GPVDGVGLALYKKG-EDKPLQFL-DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402
             V      L+++G  + PL+ +          ++ +  +T +  G Y C   +T     
Sbjct: 146 SDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYE 205

Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEWE--ERE 458
                + ++++VV    KPSLSA P    + G+ +TL C  R    +   S E E  E  
Sbjct: 206 LSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELR 265

Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYV 516
                 VNG F  +   G  T  G Y C       P+ WS  S+PL    P      +  
Sbjct: 266 LTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPL----PVSVTGNSRH 321

Query: 517 LNEAIRLSLIMQLVALLLVVLWIRW 541
           L+  I  S+++   A+LL  L  RW
Sbjct: 322 LHVLIGTSVVIIPFAILLFFLLHRW 346



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 50/182 (27%), Positives = 75/182 (41%), Gaps = 12/182 (6%)

Query: 52  ENITLWCRSPSRISSKFLLLKD---KTQMTWIRPSHKT-FQVSFLIGALTESNAGLYRCC 107
           E + L C S  R   +FLL ++   +  +  +   H    QV++ +G +T + AG YRC 
Sbjct: 138 ETVILQCWSDVRFE-RFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRC- 195

Query: 108 YWKETGW----SKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFML 163
           +   T      S PS  L++   G   KP    Q       G NV + C       ++ L
Sbjct: 196 FGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255

Query: 164 FKEGYAEPVDYQVPTGTMAIFSID-NLTPEDEGV-YICRTHIQMLPTLWSEPSNPLKLVV 221
            +E  A  +           F  +  L P   G  Y C    + LP  WS+PS+PL + V
Sbjct: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSV 315

Query: 222 AG 223
            G
Sbjct: 316 TG 317


>gi|208879429 hypothetical LOC441864 [Homo sapiens]
          Length = 271

 Score =  128 bits (322), Expect = 3e-29
 Identities = 87/216 (40%), Positives = 108/216 (50%), Gaps = 8/216 (3%)

Query: 967  TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEAT-SMQLWGSTSNDGAFPI 1025
            + PKP L A PSSVVP   NVTL C  P  GV ++L K G    S +   ST     F +
Sbjct: 25   SLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHL 84

Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085
             N+   + G Y+C Y+   +  I  Q S+ L LLVTG L KP L       V  G  +TL
Sbjct: 85   NNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTL 144

Query: 1086 QCQGELPDSTFV-----LLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140
            QCQ    D  FV     LLK G   P++ Q P+G   DF +  V   D+G YSC+YY   
Sbjct: 145  QCQKR--DQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTK 202

Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLG 1176
            +PF AS  SD LEI VT  P   S +       +LG
Sbjct: 203  SPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLG 238



 Score =  105 bits (261), Expect = 4e-22
 Identities = 73/195 (37%), Positives = 99/195 (50%), Gaps = 8/195 (4%)

Query: 777 PKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLI 836
           PKP    W S VV   + VT  C TP + +SF+L K G  + S     ++ GA  A F +
Sbjct: 27  PKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGA--AEFHL 84

Query: 837 ISVGIGDGGNYSCRYYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
            ++ + + G Y+C YY  +   I S+ SD + L+VT    KP L       V  G  V L
Sbjct: 85  NNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTL 144

Query: 894 RCQGT---FQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950
           +CQ     F  + FALL+ G   P+Q +S +G   DF L  V A D+GNYSC+YY+T   
Sbjct: 145 QCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSP 204

Query: 951 NRGSYLSMPLMIWVT 965
              S  S  L I VT
Sbjct: 205 FWASEPSDQLEILVT 219



 Score =  104 bits (260), Expect = 5e-22
 Identities = 77/235 (32%), Positives = 111/235 (47%), Gaps = 16/235 (6%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG----AQEPLEQQRPSGYRA 1117
            G LPKPSL A P  +V    N+TL+C       +FVL K G    + +PL+    +   A
Sbjct: 24   GSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGA---A 80

Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGK 1177
            +F +  ++  ++G Y+C YY  ++P   S  SD L + VT    KP L  +       G 
Sbjct: 81   EFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGG 140

Query: 1178 DITLQCRGP---LPGVEFVLEHDGEEAPQQF----SEDGDFVINNVEGKGIGNYSCSYRL 1230
             +TLQC+        + F L   G  +P Q      ++ DF + +V     GNYSC Y  
Sbjct: 141  RVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQ 200

Query: 1231 QAYPDIWSEPSDPLELVGAA--GPVAQECTVGNIVRSSLIVVVVVALGVVLAIEW 1283
               P   SEPSD LE++     G  +   ++GN VR  L  V+VV +G  L   W
Sbjct: 201  TKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAW 255



 Score = 90.9 bits (224), Expect = 7e-18
 Identities = 67/201 (33%), Positives = 94/201 (46%), Gaps = 13/201 (6%)

Query: 679 GTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGE-QEPVQQLGAVGREAF 734
           G   LPKP +SA P+        + LRC     G+ F L K G   E  + L +    A 
Sbjct: 22  GDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAE 81

Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794
           F +  ++ ++ G Y+C  + +  P   S+ S+ L L++     KPF +T+    VT G R
Sbjct: 82  FHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGR 141

Query: 795 VTFNCSTPHQ---HMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851
           VT  C    Q    + F L K G+    S     SP      F ++ V  GD GNYSC Y
Sbjct: 142 VTLQCQKRDQLFVPIMFALLKAGT---PSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMY 198

Query: 852 YDFS--IW-SEPSDPVELVVT 869
           Y      W SEPSD +E++VT
Sbjct: 199 YQTKSPFWASEPSDQLEILVT 219



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 14/198 (7%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHV--PLQFRSVSGNSADFLLH 930
            PKP+L A P  VV    +V LRC    +G+ F L + G  +  P    S  G +A+F L+
Sbjct: 27   PKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEG-AAEFHLN 85

Query: 931  TVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLW 990
             +   ++G Y+C YY     +  S  S  L++ VT    KP+L       V  G  VTL 
Sbjct: 86   NLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQ 145

Query: 991  CRGPVH---GVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYH----PD 1043
            C+        + + L K G  + +QL      +  F + +++    G YSC Y+    P 
Sbjct: 146  CQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPF 205

Query: 1044 WTSSIKIQPSNTLELLVT 1061
            W S    +PS+ LE+LVT
Sbjct: 206  WAS----EPSDQLEILVT 219



 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 71/241 (29%), Positives = 100/241 (41%), Gaps = 18/241 (7%)

Query: 319 TFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG----EDKPLQFLDATSIDDN 374
           + PK  L A PS+VV    NV+LRC  P  GV   L K G      KPL      S +  
Sbjct: 25  SLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLD-----STEGA 79

Query: 375 TSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLG 434
             F LNN+   + G Y+C Y       I     + + L+V     KP L  +       G
Sbjct: 80  AEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAG 139

Query: 435 KAITLQC----RVSHPVLEFSLEWEERETFQKFSVNG---DFIISNVDGKGTGTYSCSYR 487
             +TLQC    ++  P++   L+       Q  S  G   DF + +V     G YSC Y 
Sbjct: 140 GRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYY 199

Query: 488 VETHPNIWSHRSEPLKLM--GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWKCRR 545
               P   S  S+ L+++   P G  + NY L   +RL L   +V ++   L   W  R 
Sbjct: 200 QTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRN 259

Query: 546 L 546
           +
Sbjct: 260 V 260



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 65/215 (30%), Positives = 98/215 (45%), Gaps = 13/215 (6%)

Query: 568 ALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKD 627
           +LLC  LC G      +  +P P    W  +  P     N+TL C +P+     FVL K 
Sbjct: 7   SLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPAN--SNVTLRCWTPARGVS-FVLRKG 63

Query: 628 GTGWIATRPA-SEQVRAAFPLGALTQSHTGSYHCHSWEEMA---VSEPSEALELVGTDIL 683
           G    + +P  S +  A F L  L   + G Y C  + + +   +S+ S+ L L+ T  L
Sbjct: 64  GIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHL 123

Query: 684 PKPVISA---SPTIRGQELQLRCKG---WLAGMGFALYKEGEQEPVQQLGAVGREAFFTI 737
            KP +          G  + L+C+        + FAL K G   P+Q     G+E  F++
Sbjct: 124 SKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSL 183

Query: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVI 772
             +   D GNYSC  +  K PF  SEPS+ LE+++
Sbjct: 184 VDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILV 218



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 62/222 (27%), Positives = 97/222 (43%), Gaps = 7/222 (3%)

Query: 223 GLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFF 282
           G  PKP+L+A P  ++    ++ LRC  P  G++F L +   + +S     + +  A F 
Sbjct: 24  GSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFH 83

Query: 283 FQSLKIQDTGHYLCFYY--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVS 340
             +LK+++ G Y C YY   + +  S  SDVL + VT    K +L       V  G  V+
Sbjct: 84  LNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVT 143

Query: 341 LRCRGPVD---GVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLT 397
           L+C+        +  AL K G   P+Q    +       F L +VT  D G YSC Y  T
Sbjct: 144 LQCQKRDQLFVPIMFALLKAGTPSPIQL--QSPAGKEIDFSLVDVTAGDAGNYSCMYYQT 201

Query: 398 WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439
                     + +E++V   P   S +       +LG A  +
Sbjct: 202 KSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVI 243



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 15/214 (7%)

Query: 20  LFCIRMSLGMTSIVMD---PQPEL--WIESNYPQAPWENITLWCRSPSRISSKFLLLKDK 74
           L C R+ +G      D   P+P L  W  S  P     N+TL C +P+R  S F+L K  
Sbjct: 8   LLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPAN--SNVTLRCWTPARGVS-FVLRKGG 64

Query: 75  TQMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETG---WSKPSKVLELEAPGQLP 130
             +   +P   T   + F +  L   NAG Y C Y+++      S+ S VL L   G L 
Sbjct: 65  IILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLS 124

Query: 131 KPIFWIQAETPALPGCNVNILCHGWLQ---DLVFMLFKEGYAEPVDYQVPTGTMAIFSID 187
           KP            G  V + C    Q    ++F L K G   P+  Q P G    FS+ 
Sbjct: 125 KPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLV 184

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVV 221
           ++T  D G Y C  +    P   SEPS+ L+++V
Sbjct: 185 DVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILV 218



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 57/202 (28%), Positives = 87/202 (43%), Gaps = 17/202 (8%)

Query: 127 GQLPKPIF--WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA----EPVDYQVPTGT 180
           G LPKP    W  +  PA    NV + C    + + F+L K G      +P+D    T  
Sbjct: 24  GSLPKPSLSAWPSSVVPA--NSNVTLRCWTPARGVSFVLRKGGIILESPKPLD---STEG 78

Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240
            A F ++NL   + G Y C  + +  P + S+ S+ L L+V G   KP L  +    +  
Sbjct: 79  AAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTA 138

Query: 241 GESLNLRCQGP---IYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297
           G  + L+CQ        + FAL++          +     E +F    +   D G+Y C 
Sbjct: 139 GGRVTLQCQKRDQLFVPIMFALLKA-GTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCM 197

Query: 298 YYD--ASYRGSLLSDVLKIWVT 317
           YY   + +  S  SD L+I VT
Sbjct: 198 YYQTKSPFWASEPSDQLEILVT 219


>gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like
            receptor, partial [Homo sapiens]
          Length = 256

 Score =  119 bits (299), Expect = 1e-26
 Identities = 90/248 (36%), Positives = 117/248 (47%), Gaps = 18/248 (7%)

Query: 862  DPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPL 915
            DP   V     PKPTL A+PG V+  G  V LRCQG+ +   + L +E         +P 
Sbjct: 16   DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75

Query: 916  QFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFA 975
            +          F + ++  E +G Y CIY   T     S  S PL + VT  + KP L A
Sbjct: 76   ELVK----KGQFPILSITWEHAGRYCCIYGSHTAGLSES--SDPLELVVT-AYSKPTLSA 128

Query: 976  EPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISG 1030
             PS VV  G NVT+ C   V   G+IL KEGE    Q   S S+        F +  +S 
Sbjct: 129  LPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSP 188

Query: 1031 TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGE 1090
            +    Y C  +      +   PS+ L LLV G+  KPSL  QPGP+VAPGE +T QC  +
Sbjct: 189  SRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSD 248

Query: 1091 LPDSTFVL 1098
                 FVL
Sbjct: 249  PGYDRFVL 256



 Score =  112 bits (280), Expect = 2e-24
 Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 17/258 (6%)

Query: 565 IVTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623
           I+T L+C GL    L   T +   P PKP LWAE    +     +TL C+  S  T+E+ 
Sbjct: 4   ILTVLICLGLS---LDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYH 59

Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHC-HSWEEMAVSEPSEALELVGT 680
           L ++     WI   P     +  FP+ ++T  H G Y C +      +SE S+ LELV T
Sbjct: 60  LYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVT 119

Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR-----E 732
               KP +SA P+     G  + ++C   +A  GF L KEGE E  Q L +         
Sbjct: 120 -AYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSR 178

Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           A F++  +      +Y C  +  + P+ WS PS+ L L++  +  KP       PVV PG
Sbjct: 179 AIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPG 238

Query: 793 ARVTFNCSTPHQHMSFIL 810
            ++TF C +   +  F+L
Sbjct: 239 EKLTFQCGSDPGYDRFVL 256



 Score =  110 bits (276), Expect = 7e-24
 Identities = 84/237 (35%), Positives = 114/237 (48%), Gaps = 18/237 (7%)

Query: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLW-----GSTSNDGAF 1023
            PKP L+AEP SV+  G  VTL C+G +    Y L++E +     LW           G F
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTA---LWITRIPQELVKKGQF 83

Query: 1024 PITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENM 1083
            PI +I+    GRY CC +   T+ +  + S+ LEL+VT    KP+L A P P+V  G N+
Sbjct: 84   PILSITWEHAGRY-CCIYGSHTAGLS-ESSDPLELVVTAY-SKPTLSALPSPVVTSGGNV 140

Query: 1084 TLQCQGELPDSTFVLLKEGAQEPLE-----QQRPSGYRADFWMPAVRGEDSGIYSCVYYL 1138
            T+QC  ++    F+L KEG  E  +            RA F +  V       Y C  Y 
Sbjct: 141  TIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYD 200

Query: 1139 DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVE-FVL 1194
               P+  S  SD L + V     KPSLS  P  +   G+ +T QC G  PG + FVL
Sbjct: 201  SRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC-GSDPGYDRFVL 256



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 80/229 (34%), Positives = 108/229 (47%), Gaps = 25/229 (10%)

Query: 683 LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734
           LPKP + A P     +G  + LRC+G L    + LY+E +         Q+L   G+   
Sbjct: 26  LPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQ--- 82

Query: 735 FTIQRMEDKDEGNYSC--RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792
           F I  +  +  G Y C   +HT       SE S+PLELV+   Y KP      SPVVT G
Sbjct: 83  FPILSITWEHAGRYCCIYGSHTAGL----SESSDPLELVVTA-YSKPTLSALPSPVVTSG 137

Query: 793 ARVTFNCSTPHQHMSFILYKDGSEI---ASSDRSWASPGASAAHFLIISVGIGDGGNYSC 849
             VT  C +      FIL K+G +      +  S A  G+S A F +  V      +Y C
Sbjct: 138 GNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHAR-GSSRAIFSVGPVSPSRRWSYRC 196

Query: 850 RYYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRC 895
             YD     +WS PSD + L+V     KP+L  QPGPVV PG+ +  +C
Sbjct: 197 YGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 75/241 (31%), Positives = 108/241 (44%), Gaps = 13/241 (5%)

Query: 19  LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75
           +L C+ +SL   + V     P+P LW E          +TL C+  S  + ++ L ++K 
Sbjct: 7   VLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYHLYREKK 65

Query: 76  QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132
              WI   P     +  F I ++T  +AG Y C Y   T G S+ S  LEL       KP
Sbjct: 66  TALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTAY-SKP 124

Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187
                       G NV I C   +    F+L KEG  E              + AIFS+ 
Sbjct: 125 TLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVG 184

Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247
            ++P     Y C  +    P +WS PS+ L L+V G+  KP+L+  PGP++APGE L  +
Sbjct: 185 PVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQ 244

Query: 248 C 248
           C
Sbjct: 245 C 245



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 72/231 (31%), Positives = 106/231 (45%), Gaps = 5/231 (2%)

Query: 215 NPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYH-KK 273
           +P   V AG  PKPTL A PG ++  G  + LRCQG +    + L R +          +
Sbjct: 16  DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75

Query: 274 TIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVV 333
            +  +  F   S+  +  G Y C Y   +   S  SD L++ VT  + K  L A PS VV
Sbjct: 76  ELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVT-AYSKPTLSALPSPVV 134

Query: 334 QMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIY 390
             G NV+++C   V   G  L K+GED+  Q L++ S    +S   F +  V+ S    Y
Sbjct: 135 TSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSY 194

Query: 391 SCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC 441
            C+   +    +     + + L+V     KPSLS  P  V   G+ +T QC
Sbjct: 195 RCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/197 (32%), Positives = 93/197 (47%), Gaps = 14/197 (7%)

Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119
            G LPKP+L A+PG ++  G  +TL+CQG L    + L +E        + P     +  F
Sbjct: 24   GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQF 83

Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179
             + ++  E +G Y C+Y   S     S  SD LE+ VT    KP+LSA PS +   G ++
Sbjct: 84   PILSITWEHAGRYCCIY--GSHTAGLSESSDPLELVVT-AYSKPTLSALPSPVVTSGGNV 140

Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQ--------QFSEDGDFVINNVEGKGIGNYSCSYRL 1230
            T+QC   +    F+L  +GE E PQ        + S    F +  V      +Y C    
Sbjct: 141  TIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYD 200

Query: 1231 QAYPDIWSEPSDPLELV 1247
               P +WS PSD L L+
Sbjct: 201  SRAPYVWSLPSDLLGLL 217



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 69/223 (30%), Positives = 93/223 (41%), Gaps = 12/223 (5%)

Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834
           PKP    WA P  V+T G+ VT  C    +   + LY++        R           F
Sbjct: 27  PKPTL--WAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRI-PQELVKKGQF 83

Query: 835 LIISVGIGDGGNYSCRYYDFSIW-SEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893
            I+S+     G Y C Y   +   SE SDP+ELVVT  Y KPTL A P PVV  G +V +
Sbjct: 84  PILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA-YSKPTLSALPSPVVTSGGNVTI 142

Query: 894 RCQGTFQGMRFALLQEGAHVPLQ-----FRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948
           +C        F L +EG     Q       +   + A F +  V      +Y C  Y++ 
Sbjct: 143 QCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSR 202

Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991
                S  S  L + V     KP L  +P  VV  G+ +T  C
Sbjct: 203 APYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 8/96 (8%)

Query: 1161 PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGDFVIN 1214
            PKP+L A P ++   G  +TL+C+G L   E+ L  + + A      PQ+  + G F I 
Sbjct: 27   PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86

Query: 1215 NVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAA 1250
            ++  +  G Y C Y   ++    SE SDPLELV  A
Sbjct: 87   SITWEHAGRYCCIYG--SHTAGLSESSDPLELVVTA 120



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 8/93 (8%)

Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETF------QKFSVNGDFIIS 472
           PKP+L A P +V   G  +TL+C+ S    E+ L  E++         Q+    G F I 
Sbjct: 27  PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86

Query: 473 NVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505
           ++  +  G Y C Y   +H    S  S+PL+L+
Sbjct: 87  SITWEHAGRYCCIY--GSHTAGLSESSDPLELV 117


>gi|134268644 killer cell immunoglobulin-like receptor, three domains,
            long cytoplasmic tail, 1 precursor [Homo sapiens]
          Length = 444

 Score =  118 bits (295), Expect = 4e-26
 Identities = 100/338 (29%), Positives = 155/338 (45%), Gaps = 26/338 (7%)

Query: 970  KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029
            KP+L A PS+VVP G +VTL C        ++L+KE +   + ++       +F ++ ++
Sbjct: 28   KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHIPIFHGRIFQESFNMSPVT 86

Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089
                G Y+C      + +    PSN + ++VTG   KPSLLA PGP+V  GE + LQC  
Sbjct: 87   TAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146

Query: 1090 ELPDSTFVLLKEG-AQEP---LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145
            ++    F L KEG +++P   + Q      +A+F +  +    +G Y C   +  TP+  
Sbjct: 147  DIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206

Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----EEA 1201
            S  SD L+I VT    KPSLSA P    + G+ +TL C        + L  +G       
Sbjct: 207  SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRL 266

Query: 1202 PQQFSEDGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAG-------- 1251
            P     +  F  +   G     G Y C    +  P  WS+PSDPL LV   G        
Sbjct: 267  PAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL-LVSVTGNPSSSWPS 325

Query: 1252 PVAQECTVGN------IVRSSLIVVVVVALGVVLAIEW 1283
            P       GN      ++ +S+++++ + L   L   W
Sbjct: 326  PTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLW 363



 Score =  107 bits (266), Expect = 1e-22
 Identities = 100/311 (32%), Positives = 138/311 (44%), Gaps = 23/311 (7%)

Query: 685 KPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRME 741
           KP +SA P+    RG  + LRC        F LYKE         G + +E+F  +  + 
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESF-NMSPVT 86

Query: 742 DKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCST 801
               GNY+CR      P  WS PS P+ +++   + KP       P+V  G RV   C +
Sbjct: 87  TAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146

Query: 802 PHQHMSFILYKDG-SEIASSDRSWASPGASAAHFLIISVGIGDGGNYSC----RYYDFSI 856
                 F L+K+G S+  S        G S A+F I  + +   G Y C     +  + +
Sbjct: 147 DIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206

Query: 857 WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-GAH--- 912
            S PSDP+++VVT  Y KP+L AQPGP V  G+SV L C        + L +E GAH   
Sbjct: 207 -SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265

Query: 913 VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT----DTF 968
           +P   +      ADF L    A   G Y C           S  S PL++ VT     ++
Sbjct: 266 LPAVRKVNRTFQADFPLGP--ATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323

Query: 969 PKPWLFAEPSS 979
           P P    EPSS
Sbjct: 324 PSP---TEPSS 331



 Score =  100 bits (248), Expect = 1e-20
 Identities = 96/303 (31%), Positives = 133/303 (43%), Gaps = 31/303 (10%)

Query: 778  KPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS---PGASAAHF 834
            KPF   W S VV  G  VT  C   H+  +F+LYK+       DR              F
Sbjct: 28   KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-------DRIHIPIFHGRIFQESF 80

Query: 835  LIISVGIGDGGNYSCRY---YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891
             +  V     GNY+CR    +  + WS PS+PV ++VT  + KP+LLA PGP+V  G+ V
Sbjct: 81   NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERV 140

Query: 892  ILRCQGTFQGMRFALLQEG-----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYE 946
            IL+C        F L +EG     + +  Q      + A+F +  +    +G Y C    
Sbjct: 141  ILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVSKANFSIGPMMLALAGTYRCYGSV 199

Query: 947  TTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG 1006
            T    + S  S PL I VT  + KP L A+P   V  G++VTL C        Y L +EG
Sbjct: 200  THTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259

Query: 1007 EATSMQLWGSTSNDGAFPITNISG--TSMGRYSCC----YHP-DWTSSIKIQPSNTLELL 1059
             A   +L      +  F      G  T  G Y C     + P +W+      PS+ L + 
Sbjct: 260  GAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWS-----DPSDPLLVS 314

Query: 1060 VTG 1062
            VTG
Sbjct: 315  VTG 317



 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 92/319 (28%), Positives = 134/319 (42%), Gaps = 52/319 (16%)

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIFSIDNLTPE 192
           W  A  P   G +V + CH   +   FML+KE   + +   +  G +    F++  +T  
Sbjct: 34  WPSAVVPR--GGHVTLRCHYRHRFNNFMLYKE---DRIHIPIFHGRIFQESFNMSPVTTA 88

Query: 193 DEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPI 252
             G Y CR      PT WS PSNP+ ++V G + KP+L AHPGP++  GE + L+C   I
Sbjct: 89  HAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDI 148

Query: 253 YGMTFALMRVEDLEKSFYHKKTIK--------------NEANFFFQSLKIQDTGHYLCF- 297
                        E  F HK+ I               ++ANF    + +   G Y C+ 
Sbjct: 149 M-----------FEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYG 197

Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC--RGPVDGVGLAL 354
                 Y+ S  SD L I VT  + K  L A+P   VQ G++V+L C  R   D   L+ 
Sbjct: 198 SVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSR 257

Query: 355 YKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSC-----HYLLTWKTSIRMPSHNT 409
                ++ L  +   +      F L   T+   G Y C     H    W      PS   
Sbjct: 258 EGGAHERRLPAVRKVNRTFQADFPLGPATHG--GTYRCFGSFRHSPYEWSD----PS--- 308

Query: 410 VELMVVDKPPKPSLSAWPS 428
            + ++V     PS S+WPS
Sbjct: 309 -DPLLVSVTGNPS-SSWPS 325



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 79/282 (28%), Positives = 114/282 (40%), Gaps = 12/282 (4%)

Query: 53  NITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRC---CYW 109
           ++TL C    R ++  L  +D+  +       + FQ SF +  +T ++AG Y C      
Sbjct: 44  HVTLRCHYRHRFNNFMLYKEDRIHIPIFHG--RIFQESFNMSPVTTAHAGNYTCRGSHPH 101

Query: 110 KETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA 169
             TGWS PS  + +   G   KP            G  V + C   +    F L KEG +
Sbjct: 102 SPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGIS 161

Query: 170 EPVDY---QVPTG-TMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLY 225
           +       Q+  G + A FSI  +     G Y C   +   P   S PS+PL +VV G Y
Sbjct: 162 KDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPY 221

Query: 226 PKPTLTAHPGPIMAPGESLNLRCQG-PIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQ 284
            KP+L+A PGP +  GES+ L C     Y M          E+     + +       F 
Sbjct: 222 EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFP 281

Query: 285 SLKIQDTGHYLCF--YYDASYRGSLLSDVLKIWVTDTFPKTW 324
                  G Y CF  +  + Y  S  SD L + VT     +W
Sbjct: 282 LGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 71/260 (27%), Positives = 115/260 (44%), Gaps = 38/260 (14%)

Query: 644 AFPLGALTQSHTGSYHC---HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQ 697
           +F +  +T +H G+Y C   H       S PS  + ++ T    KP + A P      G+
Sbjct: 79  SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGE 138

Query: 698 ELQLRCKGWLAGMGFALYKEG-EQEPVQQLGAVG---REAFFTIQRMEDKDEGNYSCRTH 753
            + L+C   +    F L+KEG  ++P + +G +     +A F+I  M     G Y C   
Sbjct: 139 RVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGS 198

Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKD 813
               P++ S PS+PL++V+   Y KP       P V  G  VT +CS+   +  + L ++
Sbjct: 199 VTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSRE 258

Query: 814 GS-------EIASSDRSWAS--PGASAAHFLIISVGIGDGGNYSC----RYYDFSIWSEP 860
           G         +   +R++ +  P   A H          GG Y C    R+  +  WS+P
Sbjct: 259 GGAHERRLPAVRKVNRTFQADFPLGPATH----------GGTYRCFGSFRHSPYE-WSDP 307

Query: 861 SDPVELVVT----EFYPKPT 876
           SDP+ + VT      +P PT
Sbjct: 308 SDPLLVSVTGNPSSSWPSPT 327



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 75/286 (26%), Positives = 116/286 (40%), Gaps = 12/286 (4%)

Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286
           KP L+A P  ++  G  + LRC        F L + + +    +H +  +   N     +
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESFNM--SPV 85

Query: 287 KIQDTGHYLC--FYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344
                G+Y C   +  +    S  S+ + I VT    K  LLA P  +V+ G+ V L+C 
Sbjct: 86  TTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145

Query: 345 GPVDGVGLALYKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402
             +      L+K+G  K    L     D     +F +  +  +  G Y C+  +T     
Sbjct: 146 SDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQ 205

Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEW--EERE 458
                + ++++V     KPSLSA P    + G+++TL C  R S+ +   S E    ER 
Sbjct: 206 LSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265

Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPL 502
                 VN  F      G  T  GTY C       P  WS  S+PL
Sbjct: 266 LPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL 311



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 40/290 (13%)

Query: 420 KPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEER---ETFQKFSVNGDFIISNVDG 476
           KP LSAWPS V   G  +TL+C   H    F L  E+R     F        F +S V  
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESFNMSPVTT 87

Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLS----LIMQLVAL 532
              G Y+C       P  WS  S P+ +M    +   + + +    +     +I+Q  + 
Sbjct: 88  AHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSD 147

Query: 533 LLVVLWIRWKCRRLRIREAWLLGTAQ----------GVTMLFIVTALLCCGLCNGVLIE- 581
           ++   +   K   +    + L+G             G  ML +     C G       + 
Sbjct: 148 IMFEHFFLHK-EGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206

Query: 582 -------ETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIAT 634
                  +  +  P  KP L A+    +   +++TL C S S S   + L ++G      
Sbjct: 207 SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRS-SYDMYHLSREGGAHERR 265

Query: 635 RPASEQV----RAAFPLGALTQSHTGSYHC-----HSWEEMAVSEPSEAL 675
            PA  +V    +A FPLG  T  H G+Y C     HS  E   S+PS+ L
Sbjct: 266 LPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEW--SDPSDPL 311



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 12/154 (7%)

Query: 642 RAAFPLGALTQSHTGSYHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIR--- 695
           +A F +G +  +  G+Y C+   +     +S PS+ L++V T    KP +SA P  +   
Sbjct: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236

Query: 696 GQELQLRCKGWLAGMGFALYKEG--EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTH 753
           G+ + L C    +   + L +EG   +  +  +  V R              G Y C   
Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGS 296

Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787
               P++WS+PS+PL LV     P     +W SP
Sbjct: 297 FRHSPYEWSDPSDPL-LVSVTGNPS---SSWPSP 326


>gi|134133244 killer cell immunoglobulin-like receptor, three domains,
            short cytoplasmic tail, 1 [Homo sapiens]
          Length = 382

 Score =  117 bits (294), Expect = 6e-26
 Identities = 101/338 (29%), Positives = 152/338 (44%), Gaps = 23/338 (6%)

Query: 970  KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029
            KP+L A PS+VVP G +VTL C        ++L+KE         G    +G F ++ ++
Sbjct: 28   KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG-FNMSPVT 86

Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089
                G Y+C      + +    PSN + ++VTG   KPSLLA PGP+V  GE + LQC  
Sbjct: 87   TAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146

Query: 1090 ELPDSTFVLLKEG-AQEP---LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145
            ++    F L KE  +++P   + Q      +A+F + ++    +G Y C   +  TP+  
Sbjct: 147  DIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQL 206

Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----EEA 1201
            S  SD L+I VT    KPSLSA P    + G+ +TL C        + L  +G       
Sbjct: 207  SAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRL 266

Query: 1202 PQQFSEDGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAG-------- 1251
            P     +  F  +   G     G Y C    +  P  WS+PSDPL LV   G        
Sbjct: 267  PAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL-LVSVTGNPSSSWPS 325

Query: 1252 PVAQECTVGNIVRSSLIV---VVVVALGVVLAIEWKKW 1286
            P       GN+    +++   VV +   ++L     +W
Sbjct: 326  PTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRW 363



 Score =  117 bits (294), Expect = 6e-26
 Identities = 99/307 (32%), Positives = 134/307 (43%), Gaps = 19/307 (6%)

Query: 874  KPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA-HVPLQFRSVSGNSADFLLHTV 932
            KP L A P  VV  G  V LRC    +   F L +E   HVP+    +      F +  V
Sbjct: 28   KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG--FNMSPV 85

Query: 933  GAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCR 992
                +GNY+C           S  S P++I VT    KP L A P  +V  G+ V L C 
Sbjct: 86   TTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145

Query: 993  GPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSI 1048
              +    + LHKE  +          +DG     F I ++     G Y C      T   
Sbjct: 146  SDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQ 205

Query: 1049 KIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE--- 1105
               PS+ L+++VTGL  KPSL AQPGP V  GE++TL C        + L +EG      
Sbjct: 206  LSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265

Query: 1106 -PLEQQRPSGYRADFWM-PAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKP 1163
             P  ++    ++ADF + PA  G   G Y C      +P+  S+ SD L + VT  P   
Sbjct: 266  LPAVRKVNRTFQADFPLGPATHG---GTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPS-- 320

Query: 1164 SLSAWPS 1170
              S+WPS
Sbjct: 321  --SSWPS 325



 Score =  105 bits (263), Expect = 2e-22
 Identities = 100/311 (32%), Positives = 136/311 (43%), Gaps = 23/311 (7%)

Query: 685 KPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRME 741
           KP +SA P+    RG  + LRC        F LYKE         G + +E F  +  + 
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGF-NMSPVT 86

Query: 742 DKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCST 801
               GNY+CR      P  WS PS P+ +++   + KP       P+V  G RV   C +
Sbjct: 87  TAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146

Query: 802 PHQHMSFILYKDG-SEIASSDRSWASPGASAAHFLIISVGIGDGGNYSC----RYYDFSI 856
                 F L+K+  S+  S        G S A+F I S+     G Y C     +  + +
Sbjct: 147 DIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQL 206

Query: 857 WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-GAH--- 912
            S PSDP+++VVT  Y KP+L AQPGP V  G+SV L C        + L +E GAH   
Sbjct: 207 -SAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265

Query: 913 VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT----DTF 968
           +P   +      ADF L    A   G Y C           S  S PL++ VT     ++
Sbjct: 266 LPAVRKVNRTFQADFPLGP--ATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323

Query: 969 PKPWLFAEPSS 979
           P P    EPSS
Sbjct: 324 PSP---TEPSS 331



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 93/319 (29%), Positives = 134/319 (42%), Gaps = 52/319 (16%)

Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAI--FSIDNLTPE 192
           W  A  P   G +V + CH   +   FML+KE   + +   +  G +    F++  +T  
Sbjct: 34  WPSAVVPR--GGHVTLRCHYRHRFNNFMLYKE---DRIHVPIFHGRIFQEGFNMSPVTTA 88

Query: 193 DEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPI 252
             G Y CR      PT WS PSNP+ ++V G + KP+L AHPGP++  GE + L+C   I
Sbjct: 89  HAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDI 148

Query: 253 YGMTFALMRVEDLEKSFYHKKTIK--------------NEANFFFQSLKIQDTGHYLCF- 297
                        E  F HK+ I               ++ANF   S+     G Y C+ 
Sbjct: 149 M-----------FEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197

Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC--RGPVDGVGLAL 354
                 Y+ S  SD L I VT  + K  L A+P   VQ G++V+L C  R   D   L+ 
Sbjct: 198 SVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSR 257

Query: 355 YKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSC-----HYLLTWKTSIRMPSHNT 409
                ++ L  +   +      F L   T+   G Y C     H    W      PS   
Sbjct: 258 EGGAHERRLPAVRKVNRTFQADFPLGPATHG--GTYRCFGSFRHSPYEWSD----PS--- 308

Query: 410 VELMVVDKPPKPSLSAWPS 428
            + ++V     PS S+WPS
Sbjct: 309 -DPLLVSVTGNPS-SSWPS 325



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 12/282 (4%)

Query: 53  NITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCY---W 109
           ++TL C    R ++  L  +D+  +       + FQ  F +  +T ++AG Y C      
Sbjct: 44  HVTLRCHYRHRFNNFMLYKEDRIHVPIFHG--RIFQEGFNMSPVTTAHAGNYTCRGSHPH 101

Query: 110 KETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA 169
             TGWS PS  + +   G   KP            G  V + C   +    F L KE  +
Sbjct: 102 SPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWIS 161

Query: 170 EPVDY---QVPTG-TMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLY 225
           +       Q+  G + A FSI ++     G Y C   +   P   S PS+PL +VV GLY
Sbjct: 162 KDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLY 221

Query: 226 PKPTLTAHPGPIMAPGESLNLRCQG-PIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQ 284
            KP+L+A PGP +  GES+ L C     Y M          E+     + +       F 
Sbjct: 222 EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFP 281

Query: 285 SLKIQDTGHYLCF--YYDASYRGSLLSDVLKIWVTDTFPKTW 324
                  G Y CF  +  + Y  S  SD L + VT     +W
Sbjct: 282 LGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 74/286 (25%), Positives = 116/286 (40%), Gaps = 12/286 (4%)

Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286
           KP L+A P  ++  G  + LRC        F L + + +    +H +  +    F    +
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQE--GFNMSPV 85

Query: 287 KIQDTGHYLC--FYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344
                G+Y C   +  +    S  S+ + I VT    K  LLA P  +V+ G+ V L+C 
Sbjct: 86  TTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145

Query: 345 GPVDGVGLALYKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402
             +      L+K+   K    L     D     +F + ++  +  G Y C+  +T     
Sbjct: 146 SDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQ 205

Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEW--EERE 458
                + ++++V     KPSLSA P    + G+++TL C  R S+ +   S E    ER 
Sbjct: 206 LSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265

Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPL 502
                 VN  F      G  T  GTY C       P  WS  S+PL
Sbjct: 266 LPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL 311



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 12/154 (7%)

Query: 642 RAAFPLGALTQSHTGSYHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIR--- 695
           +A F +G++ ++  G+Y C+   +     +S PS+ L++V T +  KP +SA P  +   
Sbjct: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236

Query: 696 GQELQLRCKGWLAGMGFALYKEG--EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTH 753
           G+ + L C    +   + L +EG   +  +  +  V R              G Y C   
Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGS 296

Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787
               P++WS+PS+PL LV     P     +W SP
Sbjct: 297 FRHSPYEWSDPSDPL-LVSVTGNPS---SSWPSP 326



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 73/294 (24%), Positives = 113/294 (38%), Gaps = 48/294 (16%)

Query: 420 KPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEER---ETFQKFSVNGDFIISNVDG 476
           KP LSAWPS V   G  +TL+C   H    F L  E+R     F        F +S V  
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGFNMSPVTT 87

Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVV 536
              G Y+C       P  WS  S P+ +M    +   + + +       +++    +++ 
Sbjct: 88  AHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHP----GPLVKSGERVILQ 143

Query: 537 LWIRWKCRRLRIREAW-------LLG------TAQGVTMLFIVTALLCCGLCNGVLIEET 583
            W         + + W       L+G      +    ++  ++ AL     C G  +  T
Sbjct: 144 CWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG-SVTHT 202

Query: 584 EIVMPTP-------------KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTG 630
              +  P             KP L A+    +   +++TL C S S S   + L ++G  
Sbjct: 203 PYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRS-SYDMYHLSREGGA 261

Query: 631 WIATRPASEQV----RAAFPLGALTQSHTGSYHC-----HSWEEMAVSEPSEAL 675
                PA  +V    +A FPLG  T  H G+Y C     HS  E   S+PS+ L
Sbjct: 262 HERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEW--SDPSDPL 311


>gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]
          Length = 339

 Score =  117 bits (294), Expect = 6e-26
 Identities = 105/326 (32%), Positives = 139/326 (42%), Gaps = 50/326 (15%)

Query: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028
            PKP L A PSS+VP+ + VTL C+GP    G  L++  + +S +      +     I  +
Sbjct: 26   PKPSLQALPSSLVPLEKPVTLRCQGPP---GVDLYRLEKLSSSRY----QDQAVLFIPAM 78

Query: 1029 SGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQ 1088
              +  GRY C Y      S+   PS+ LEL+ TG+  KPSL AQPGP V+ G ++TLQCQ
Sbjct: 79   KRSLAGRYRCSYQ---NGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQ 135

Query: 1089 GELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNH 1148
                   F L KEG   P +      YRA F +  V    SG Y C  +    P+  S  
Sbjct: 136  TRYGFDQFALYKEGDPAPYKNPE-RWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAP 194

Query: 1149 SDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED 1208
            SD LE+ VT     PS                L    P P  EF       EA  + +  
Sbjct: 195  SDPLELVVTGTSVTPS---------------RLPTEPPSPVAEF------SEATAELTVS 233

Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVGNIVRSSLI 1268
                +   E                    S  + P E    AGP  Q  T GN+VR  L 
Sbjct: 234  FTNEVFTTETSR-----------------SITASPKESDSPAGPARQYYTKGNLVRICLG 276

Query: 1269 VVVVVALGVVLAIEW-KKWPRLRTRG 1293
             V+++ L   LA +W  +  RLR RG
Sbjct: 277  AVILIILAGFLAEDWHSRRKRLRHRG 302



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 82/275 (29%), Positives = 119/275 (43%), Gaps = 23/275 (8%)

Query: 567 TALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLK 626
           TAL C GLC G +  ++    P PKP L A  +  +   K +TL C+ P G    + L K
Sbjct: 6   TALFCLGLCLGRVPAQSG---PLPKPSLQALPSSLVPLEKPVTLRCQGPPG-VDLYRLEK 61

Query: 627 DGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKP 686
             +       +  Q +A   + A+ +S  G Y C        S PS+ LELV T +  KP
Sbjct: 62  LSS-------SRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKP 114

Query: 687 VISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRMEDK 743
            +SA P      G ++ L+C+       FALYKEG+  P +      R A F I  +   
Sbjct: 115 SLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYR-ASFPIITVTAA 173

Query: 744 DEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPH 803
             G Y C + + + P+ WS PS+PLELV+      P       P   P     F+ +T  
Sbjct: 174 HSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPS----RLPTEPPSPVAEFSEATAE 229

Query: 804 QHMSF----ILYKDGSEIASSDRSWASPGASAAHF 834
             +SF       +    I +S +   SP   A  +
Sbjct: 230 LTVSFTNEVFTTETSRSITASPKESDSPAGPARQY 264



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 68/190 (35%), Positives = 89/190 (46%), Gaps = 13/190 (6%)

Query: 1061 TGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFW 1120
            +G LPKPSL A P  +V   + +TL+CQG      + L K  +    +Q       A  +
Sbjct: 22   SGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQDQ-------AVLF 74

Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180
            +PA++   +G Y C Y   S     S  SD LE+  T    KPSLSA P      G D+T
Sbjct: 75   IPAMKRSLAGRYRCSYQNGSL---WSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVT 131

Query: 1181 LQCRGPLPGVEFVLEHDGEEAPQQFSE---DGDFVINNVEGKGIGNYSCSYRLQAYPDIW 1237
            LQC+      +F L  +G+ AP +  E      F I  V     G Y C       P +W
Sbjct: 132  LQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLW 191

Query: 1238 SEPSDPLELV 1247
            S PSDPLELV
Sbjct: 192  SAPSDPLELV 201



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 69/206 (33%), Positives = 92/206 (44%), Gaps = 12/206 (5%)

Query: 777 PKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLI 836
           PKP  +   S +V     VT  C  P           G ++   ++  +S     A   I
Sbjct: 26  PKPSLQALPSSLVPLEKPVTLRCQGP----------PGVDLYRLEKLSSSRYQDQAVLFI 75

Query: 837 ISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQ 896
            ++     G Y C Y + S+WS PSD +ELV T  + KP+L AQPGP V  G  V L+CQ
Sbjct: 76  PAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQ 135

Query: 897 GTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYL 956
             +   +FAL +EG   P +        A F + TV A  SG Y C  + +      S  
Sbjct: 136 TRYGFDQFALYKEGDPAPYK-NPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAP 194

Query: 957 SMPLMIWVTDTFPKP-WLFAEPSSVV 981
           S PL + VT T   P  L  EP S V
Sbjct: 195 SDPLELVVTGTSVTPSRLPTEPPSPV 220



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 72/224 (32%), Positives = 98/224 (43%), Gaps = 17/224 (7%)

Query: 20  LFCIRMSLGMTSIVMDPQPELWIESNYPQA--PWEN-ITLWCRSPSRISSKFLLLKDKTQ 76
           LFC+ + LG       P P+  +++  P +  P E  +TL C+ P  +        D  +
Sbjct: 8   LFCLGLCLGRVPAQSGPLPKPSLQA-LPSSLVPLEKPVTLRCQGPPGV--------DLYR 58

Query: 77  MTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIFWI 136
           +  +  S    Q    I A+  S AG YRC Y   + WS PS  LEL A G   KP    
Sbjct: 59  LEKLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSA 118

Query: 137 QAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVP-TGTMAIFSIDNLTPEDEG 195
           Q       G +V + C        F L+KEG  +P  Y+ P     A F I  +T    G
Sbjct: 119 QPGPAVSSGGDVTLQCQTRYGFDQFALYKEG--DPAPYKNPERWYRASFPIITVTAAHSG 176

Query: 196 VYICRTHIQMLPTLWSEPSNPLKLVVAG--LYPKPTLTAHPGPI 237
            Y C +     P LWS PS+PL+LVV G  + P    T  P P+
Sbjct: 177 TYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPV 220



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 50/328 (15%)

Query: 222 AGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANF 281
           +G  PKP+L A P  ++   + + LRCQGP       L R+E L  S Y     +++A  
Sbjct: 22  SGPLPKPSLQALPSSLVPLEKPVTLRCQGP---PGVDLYRLEKLSSSRY-----QDQAVL 73

Query: 282 FFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSL 341
           F  ++K    G Y C Y + S   SL SD L++  T  F K  L A+P   V  G +V+L
Sbjct: 74  FIPAMKRSLAGRYRCSYQNGSL-WSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132

Query: 342 RCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTS 401
           +C+        ALYK+G+  P +  +        SF +  VT + +G Y C+   +    
Sbjct: 133 QCQTRYGFDQFALYKEGDPAPYKNPERWY---RASFPIITVTAAHSGTYRCYSFSSRDPY 189

Query: 402 IRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQ 461
           +     + +EL+V      PS                L      PV EFS          
Sbjct: 190 LWSAPSDPLELVVTGTSVTPS---------------RLPTEPPSPVAEFS---------- 224

Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAI 521
                        +     T S +  V T     S  + P +   PAG     Y     +
Sbjct: 225 -------------EATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLV 271

Query: 522 RLSLIMQLVALLLVVLWIRWKCRRLRIR 549
           R+ L   ++ +L   L   W  RR R+R
Sbjct: 272 RICLGAVILIILAGFLAEDWHSRRKRLR 299



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 70/215 (32%), Positives = 95/215 (44%), Gaps = 32/215 (14%)

Query: 683 LPKPVISASPTIR---GQELQLRCKGWLAGMGFALYKEGEQEPVQQLGA--VGREAFFTI 737
           LPKP + A P+      + + LRC+G     G  LY+      +++L +     +A   I
Sbjct: 25  LPKPSLQALPSSLVPLEKPVTLRCQG---PPGVDLYR------LEKLSSSRYQDQAVLFI 75

Query: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTF 797
             M+    G Y C   + +    WS PS+ LELV   ++ KP       P V+ G  VT 
Sbjct: 76  PAMKRSLAGRYRC---SYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132

Query: 798 NCSTPHQHMSFILYKDGSEIA-SSDRSWASPGASAAHFLIISVGIGDGGNYSCRYYDFS- 855
            C T +    F LYK+G      +   W       A F II+V     G Y C  Y FS 
Sbjct: 133 QCQTRYGFDQFALYKEGDPAPYKNPERW-----YRASFPIITVTAAHSGTYRC--YSFSS 185

Query: 856 ----IWSEPSDPVELVVTEFYPKPTLL--AQPGPV 884
               +WS PSDP+ELVVT     P+ L    P PV
Sbjct: 186 RDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPV 220



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 72/251 (28%), Positives = 103/251 (41%), Gaps = 26/251 (10%)

Query: 873  PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTV 932
            PKP+L A P  +V   K V LRCQG   G+    L++ +    Q ++V        +  +
Sbjct: 26   PKPSLQALPSSLVPLEKPVTLRCQGP-PGVDLYRLEKLSSSRYQDQAV------LFIPAM 78

Query: 933  GAEDSGNYSCIYYETTMSNRGSYLSMP---LMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989
                +G Y C Y        GS  S+P   L +  T  F KP L A+P   V  G +VTL
Sbjct: 79   KRSLAGRYRCSY------QNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132

Query: 990  WCRGPVHGVGYILHKEGEAT---SMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTS 1046
             C+       + L+KEG+     + + W   S    FPI  ++    G Y C        
Sbjct: 133  QCQTRYGFDQFALYKEGDPAPYKNPERWYRAS----FPIITVTAAHSGTYRCYSFSSRDP 188

Query: 1047 SIKIQPSNTLELLVTGLLPKPSLL-AQPGPMVAPGENMTLQCQGELPDSTFV--LLKEGA 1103
             +   PS+ LEL+VTG    PS L  +P   VA     T +      +  F     +   
Sbjct: 189  YLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFTTETSRSIT 248

Query: 1104 QEPLEQQRPSG 1114
              P E   P+G
Sbjct: 249  ASPKESDSPAG 259



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 4/114 (3%)

Query: 208 TLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEK 267
           +LWS PS+ L+LV  G++ KP+L+A PGP ++ G  + L+CQ       FAL +  D   
Sbjct: 94  SLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGD--P 151

Query: 268 SFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDA--SYRGSLLSDVLKIWVTDT 319
           + Y        A+F   ++    +G Y C+ + +   Y  S  SD L++ VT T
Sbjct: 152 APYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGT 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,503,965
Number of Sequences: 37866
Number of extensions: 3132959
Number of successful extensions: 12611
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 185
Number of HSP's that attempted gapping in prelim test: 8169
Number of HSP's gapped (non-prelim): 2389
length of query: 1336
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1222
effective length of database: 13,930,794
effective search space: 17023430268
effective search space used: 17023430268
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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