BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo sapiens] (1336 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo... 2776 0.0 gi|45505169 immunoglobulin superfamily, member 1 isoform 2 [Homo... 473 e-133 gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (... 209 1e-53 gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A... 201 3e-51 gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 200 9e-51 gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 200 9e-51 gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 196 1e-49 gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens] 184 4e-46 gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 182 2e-45 gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 181 3e-45 gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 178 4e-44 gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 178 4e-44 gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 178 4e-44 gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 177 5e-44 gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 177 6e-44 gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 172 2e-42 gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 172 2e-42 gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 172 3e-42 gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 172 3e-42 gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens] 146 1e-34 gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens] 144 6e-34 gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens] 144 7e-34 gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens] 144 7e-34 gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 140 1e-32 gi|46488946 killer cell immunoglobulin-like receptor, three doma... 130 1e-29 gi|208879429 hypothetical LOC441864 [Homo sapiens] 128 3e-29 gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like... 119 1e-26 gi|134268644 killer cell immunoglobulin-like receptor, three dom... 118 4e-26 gi|134133244 killer cell immunoglobulin-like receptor, three dom... 117 6e-26 gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens] 117 6e-26 >gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo sapiens] Length = 1336 Score = 2776 bits (7196), Expect = 0.0 Identities = 1336/1336 (100%), Positives = 1336/1336 (100%) Query: 1 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS Sbjct: 1 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60 Query: 61 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV Sbjct: 61 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120 Query: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT Sbjct: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP Sbjct: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240 Query: 241 GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD 300 GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD Sbjct: 241 GESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYD 300 Query: 301 ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360 ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED Sbjct: 301 ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360 Query: 361 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK Sbjct: 361 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420 Query: 421 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG 480 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG Sbjct: 421 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQKFSVNGDFIISNVDGKGTG 480 Query: 481 TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540 TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR Sbjct: 481 TYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540 Query: 541 WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF 600 WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF Sbjct: 541 WKCRRLRIREAWLLGTAQGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNF 600 Query: 601 PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC 660 PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC Sbjct: 601 PLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHC 660 Query: 661 HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ 720 HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ Sbjct: 661 HSWEEMAVSEPSEALELVGTDILPKPVISASPTIRGQELQLRCKGWLAGMGFALYKEGEQ 720 Query: 721 EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF 780 EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF Sbjct: 721 EPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPF 780 Query: 781 FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG 840 FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG Sbjct: 781 FKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG 840 Query: 841 IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900 IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ Sbjct: 841 IGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900 Query: 901 GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL 960 GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL Sbjct: 901 GMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPL 960 Query: 961 MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND 1020 MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND Sbjct: 961 MIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND 1020 Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG Sbjct: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080 Query: 1081 ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140 ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS Sbjct: 1081 ENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE 1200 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE Sbjct: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEE 1200 Query: 1201 APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG 1260 APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG Sbjct: 1201 APQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVG 1260 Query: 1261 NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS 1320 NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS Sbjct: 1261 NIVRSSLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGEPGTPANS 1320 Query: 1321 PSSTSQRISVELPVPI 1336 PSSTSQRISVELPVPI Sbjct: 1321 PSSTSQRISVELPVPI 1336 >gi|45505169 immunoglobulin superfamily, member 1 isoform 2 [Homo sapiens] Length = 242 Score = 473 bits (1216), Expect = e-133 Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 1 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS Sbjct: 1 MTLDRPGEGATMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRS 60 Query: 61 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV Sbjct: 61 PSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKV 120 Query: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT Sbjct: 121 LELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGT 180 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG 223 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG Sbjct: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAG 223 Score = 187 bits (476), Expect = 4e-47 Identities = 101/238 (42%), Positives = 138/238 (57%), Gaps = 10/238 (4%) Query: 558 QGVTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSG 617 +G TML T LL C + + T IVM P+PELW E+N+P APW+N+TLWCRSPS Sbjct: 8 EGATMLKTFTVLL---FCIRMSLGMTSIVMD-PQPELWIESNYPQAPWENITLWCRSPSR 63 Query: 618 STKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALEL 677 + +F+LLKD T RP+ + + +F +GALT+S+ G Y C W+E S+PS+ LEL Sbjct: 64 ISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLEL 123 Query: 678 VGTDILPKPVI---SASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAF 734 LPKP+ + +P + G + + C GWL + F L+KEG EPV G A Sbjct: 124 EAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAI 183 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 F+I + +DEG Y CRTH + P WSEPS PL+LV+ + W +V PG Sbjct: 184 FSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGGCG---YGCWHLAIVVPG 238 Score = 96.3 bits (238), Expect = 2e-19 Identities = 61/189 (32%), Positives = 92/189 (48%), Gaps = 4/189 (2%) Query: 969 PKPWLFAEPSSVVPMGQNVTLWCRGPVH-GVGYILHKEGEATSMQLWGSTSNDGAFPITN 1027 P+P L+ E + +N+TLWCR P ++L K+ + + +F I Sbjct: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 Query: 1028 ISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087 ++ ++ G Y CCY W + +PS LEL G LPKP Q PG N+ + C Sbjct: 96 LTESNAGLYRCCY---WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152 Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147 G L D F+L KEG EP++ Q P+G A F + + ED G+Y C ++ P S Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212 Query: 1148 HSDSLEIWV 1156 S+ L++ V Sbjct: 213 PSNPLKLVV 221 Score = 80.9 bits (198), Expect = 8e-15 Identities = 57/192 (29%), Positives = 90/192 (46%), Gaps = 8/192 (4%) Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELP-DSTFVLLKEGAQEPLEQQRPSGYRADFWMPA 1123 P+P L + AP EN+TL C+ S F+LLK+ Q + ++ F + A Sbjct: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 Query: 1124 VRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183 + ++G+Y C Y+ ++ S S LE+ + PKP T G ++ + C Sbjct: 96 LTESNAGLYRCCYWKET---GWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152 Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSEDGD----FVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239 G L + F+L +G P + F I+N+ + G Y C +Q P +WSE Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212 Query: 1240 PSDPLELVGAAG 1251 PS+PL+LV A G Sbjct: 213 PSNPLKLVVAGG 224 Score = 73.6 bits (179), Expect = 1e-12 Identities = 55/193 (28%), Positives = 86/193 (44%), Gaps = 8/193 (4%) Query: 775 MYPKPFFKTWASPVVTPGARVTFNCSTPHQHMS-FILYKDGSEIASSDRSWASPGASA-- 831 M P+P ++ P +T C +P + S F+L KD +++ +W P Sbjct: 34 MDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQM-----TWIRPSHKTFQ 88 Query: 832 AHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891 FLI ++ + G Y C Y+ + WS+PS +EL PKP Q PG +V Sbjct: 89 VSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNV 148 Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSN 951 + C G Q + F L +EG P+ ++ +G A F + + ED G Y C + + Sbjct: 149 NILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPT 208 Query: 952 RGSYLSMPLMIWV 964 S S PL + V Sbjct: 209 LWSEPSNPLKLVV 221 Score = 62.4 bits (150), Expect = 3e-09 Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 4/191 (2%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQ-GMRFALLQEGAHVPLQFRSVSGNSADFLLHT 931 P+P L + P +++ L C+ + +F LL++ + S FL+ Sbjct: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 Query: 932 VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991 + ++G Y C Y++ T ++ S + L + PKP + + + G NV + C Sbjct: 96 LTESNAGLYRCCYWKETGWSKPSKV---LELEAPGQLPKPIFWIQAETPALPGCNVNILC 152 Query: 992 RGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQ 1051 G + + ++L KEG A + T F I N++ G Y C H ++ + Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSE 212 Query: 1052 PSNTLELLVTG 1062 PSN L+L+V G Sbjct: 213 PSNPLKLVVAG 223 Score = 62.4 bits (150), Expect = 3e-09 Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 9/137 (6%) Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F I + + + G Y C E WS+PS+ LEL PKP F A PG Sbjct: 91 FLIGALTESNAGLYRCCYWKETG---WSKPSKVLELEAPGQLPKPIFWIQAETPALPGCN 147 Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYYDF 854 V C Q + F+L+K+G + + P + A F I ++ D G Y CR + Sbjct: 148 VNILCHGWLQDLVFMLFKEG---YAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 Query: 855 ---SIWSEPSDPVELVV 868 ++WSEPS+P++LVV Sbjct: 205 MLPTLWSEPSNPLKLVV 221 Score = 56.6 bits (135), Expect = 2e-07 Identities = 46/168 (27%), Positives = 67/168 (39%), Gaps = 5/168 (2%) Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQ-DLVFMLFKEGYAEPVDYQVPTGTMAIFSIDN 188 P+P WI++ P P N+ + C + F+L K+ F I Sbjct: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 Query: 189 LTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248 LT + G+Y C T WS+PS L+L G PKP PG ++N+ C Sbjct: 96 LTESNAGLYRC---CYWKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILC 152 Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLC 296 G + + F L + E Y T A F +L +D G Y+C Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFSIDNLTPEDEGVYIC 199 Score = 54.7 bits (130), Expect = 6e-07 Identities = 54/209 (25%), Positives = 84/209 (40%), Gaps = 14/209 (6%) Query: 316 VTDTFPKTWLLAR-PSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDN 374 V D P+ W+ + P A +N++L CR P L K + + + ++ + Sbjct: 33 VMDPQPELWIESNYPQAP---WENITLWCRSPSRISSKFLLLKDKTQ-MTWIRPSHKTFQ 88 Query: 375 TSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLG 434 SF + +T S+ G+Y C Y WK + +EL + PKP T G Sbjct: 89 VSFLIGALTESNAGLYRCCY---WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPG 145 Query: 435 KAITLQCRVSHPVLEFSLEWEERETFQKFSVNGD----FIISNVDGKGTGTYSCSYRVET 490 + + C L F L E + V F I N+ + G Y C ++ Sbjct: 146 CNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQM 205 Query: 491 HPNIWSHRSEPLKLM--GPAGYLTWNYVL 517 P +WS S PLKL+ G GY W+ + Sbjct: 206 LPTLWSEPSNPLKLVVAGGCGYGCWHLAI 234 Score = 53.1 bits (126), Expect = 2e-06 Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 7/191 (3%) Query: 226 PKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQS 285 P+P L AP E++ L C+ P + L+ + + ++ + +F + Sbjct: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 Query: 286 LKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKT--WLLARPSAVVQMGQNVSLRC 343 L + G Y C Y+ + S S VL++ PK W+ A A+ G NV++ C Sbjct: 96 LTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKPIFWIQAETPALP--GCNVNILC 152 Query: 344 RGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIR 403 G + + L+K+G +P+ + T F ++N+T D G+Y C + ++ Sbjct: 153 HGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIFSIDNLTPEDEGVYICRTHIQMLPTLW 210 Query: 404 MPSHNTVELMV 414 N ++L+V Sbjct: 211 SEPSNPLKLVV 221 >gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 isoform b [Homo sapiens] Length = 466 Score = 209 bits (533), Expect = 1e-53 Identities = 155/428 (36%), Positives = 210/428 (49%), Gaps = 25/428 (5%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFR-SVSGNSADFLLHT 931 PKPTL A+PG V+ G V LRCQG+ Q + L +E R G + F + + Sbjct: 27 PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIPS 86 Query: 932 VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991 + E +G Y C YY N S S PL + VT + KP L A PS VV +G NVTL C Sbjct: 87 ITWEHAGRYHCQYYS---HNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQC 143 Query: 992 RGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWTS 1046 V G+IL KEGE Q S S+ F + +S + Y C + + Sbjct: 144 VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSP 203 Query: 1047 SIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG---- 1102 + PS+ LELLV G+ KPSL QPGPMVAPGE++TLQC ++ FVL KEG Sbjct: 204 YVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDF 263 Query: 1103 AQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDK-PP 1161 Q P Q + +A+F + V G Y C Y + S SD L+I +T + Sbjct: 264 LQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQFYD 322 Query: 1162 KPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDGDFVI 1213 +PSLS P GK++TL C+ F+L +G P Q +F + Sbjct: 323 RPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRM 382 Query: 1214 NNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAA--GPVAQECTVGNIVRSSLIVVV 1271 V +G Y C L + P + S PSDPLELV +A G Q+ TV N++R + +V Sbjct: 383 GPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTVENLIRMGVAGLV 442 Query: 1272 VVALGVVL 1279 +V LG++L Sbjct: 443 LVVLGILL 450 Score = 193 bits (491), Expect = 8e-49 Identities = 138/413 (33%), Positives = 198/413 (47%), Gaps = 25/413 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ S +E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYH 59 Query: 624 LLKDGTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682 L ++ R E + FP+ ++T H G YHC + SE S+ LELV T Sbjct: 60 LYRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119 Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGRE-----AF 734 KP +SA P+ G + L+C +A GF L KEGE E Q+L + A Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F++ + +Y C + P+ WS PS+ LEL++ + KP P+V PG Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239 Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSW-ASPGASAAHFLIISVGIGDGGNYSC--RY 851 +T C + + F+LYK+G W G S A+F + V GG Y C + Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299 Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910 S WS PSDP+++++T +FY +P+L QP P V PGK+V L CQ Q F L +EG Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359 Query: 911 A-HVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959 A H PL RS N A+F + V + G Y C +++S+ LS+P Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCY---SSLSSNPYLLSLP 409 Score = 169 bits (428), Expect = 2e-41 Identities = 142/399 (35%), Positives = 190/399 (47%), Gaps = 25/399 (6%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+ G+ VT C Q + LY++ AS R PG + F Sbjct: 27 PKPTL--WAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS-ASWVRRIQEPGKNG-QF 82 Query: 835 LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894 I S+ G Y C+YY + SE SDP+ELVVT Y KPTL A P PVV G +V L+ Sbjct: 83 PIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQ 142 Query: 895 C--QGTFQGMRFALLQEGA-HVPLQFRSVS----GNSADFLLHTVGAEDSGNYSCIYYET 947 C Q F G F L +EG P + S S + A F + V +Y C Y++ Sbjct: 143 CVSQVAFDG--FILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200 Query: 948 TMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE 1007 S S L + V KP L +P +V G+++TL C V ++L+KEGE Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260 Query: 1008 ATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG- 1062 +Q G G F + +S + G+Y CY SS PS+ L++L+TG Sbjct: 261 RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYR-CYSAHNLSSEWSAPSDPLDILITGQ 319 Query: 1063 LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRAD 1118 +PSL QP P VAPG+N+TL CQ TF+L KEGA P + + +A+ Sbjct: 320 FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379 Query: 1119 FWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 F M V G Y C L S P+ S SD LE+ V+ Sbjct: 380 FRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418 Score = 131 bits (329), Expect = 5e-30 Identities = 114/412 (27%), Positives = 184/412 (44%), Gaps = 17/412 (4%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ S + ++ L ++ Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYHLYRENK 65 Query: 76 QMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134 +W+R + + F I ++T +AG Y C Y+ S+ S LEL G KP Sbjct: 66 SASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTL 125 Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSIDNL 189 G NV + C + F+L KEG E + AIFS+ + Sbjct: 126 SALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPV 185 Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQ 249 +P Y C + P +WS PS+ L+L+V G+ KP+L+ PGP++APGESL L+C Sbjct: 186 SPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCV 245 Query: 250 GPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASYRG 305 + F L + + L++ + + ++ANF + G Y C+ ++ S Sbjct: 246 SDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEW 305 Query: 306 SLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ 364 S SD L I +T F + L +P V G+NV+L C+ L K+G P Sbjct: 306 SAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPL 365 Query: 365 FL--DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 L + + + F + VT + G Y C+ L+ + + +EL+V Sbjct: 366 HLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVV 417 Score = 127 bits (319), Expect = 7e-29 Identities = 123/442 (27%), Positives = 192/442 (43%), Gaps = 46/442 (10%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFS 185 G LPKP W + + + G V + C G LQ + L++E + ++ G F Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83 Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245 I ++T E G Y C+ + SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 IPSITWEHAGRYHCQYYSHNHS---SEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140 Query: 246 LRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLCF 297 L+C + F L + + E H + + + ++ S I G Y C+ Sbjct: 141 LQCVSQVAFDGFILCKEGEDE----HPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCY 196 Query: 298 YYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALY 355 YD++ Y SL SD+L++ V K L +P +V G++++L+C V LY Sbjct: 197 AYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLY 256 Query: 356 KKGEDKPLQF--LDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELM 413 K+GE LQ + +F L V+ S G Y C+ + PS L+ Sbjct: 257 KEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILI 316 Query: 414 VVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERET 459 +PSLS P GK +TL C+ HP L E + ++ Sbjct: 317 TGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN 376 Query: 460 FQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPA--GYLTWNYVL 517 +F + V GTY C + ++P + S S+PL+L+ A G +Y + Sbjct: 377 ------QAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTV 430 Query: 518 NEAIRLSLIMQLVALLLVVLWI 539 IR M + L+LVVL I Sbjct: 431 ENLIR----MGVAGLVLVVLGI 448 Score = 106 bits (265), Expect = 1e-22 Identities = 91/301 (30%), Positives = 129/301 (42%), Gaps = 13/301 (4%) Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTI 275 P V AG PKPTL A PG ++ G + LRCQG + + L R + Sbjct: 17 PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEP 76 Query: 276 KNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQM 335 F S+ + G Y C YY ++ S SD L++ VT + K L A PS VV + Sbjct: 77 GKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTGAYSKPTLSALPSPVVTL 135 Query: 336 GQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSC 392 G NV+L+C V G L K+GED+ Q L++ S S F + V+ S Y C Sbjct: 136 GGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRC 195 Query: 393 HYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL 452 + + + + +EL+V KPSLS P + G+++TLQC F L Sbjct: 196 YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVL 255 Query: 453 EWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKL 504 E F Q +F + V G Y C Y + WS S+PL + Sbjct: 256 YKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDI 314 Query: 505 M 505 + Sbjct: 315 L 315 Score = 99.4 bits (246), Expect = 2e-20 Identities = 71/197 (36%), Positives = 104/197 (52%), Gaps = 15/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP-LEQQRPSGYRADFW 1120 G LPKP+L A+PG ++ G +TL+CQG L + L +E + + + G F Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83 Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180 +P++ E +G Y C YY + +S +SD LE+ VT KP+LSA PS + LG ++T Sbjct: 84 IPSITWEHAGRYHCQYYSHN---HSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140 Query: 1181 LQCRGPLPGVEFVLEHDGE-EAPQQFSEDG-----DFVINNVEGKGIGNYSCSYRLQAY- 1233 LQC + F+L +GE E PQ+ + + I +V G + SYR AY Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSV-GPVSPSRRWSYRCYAYD 199 Query: 1234 ---PDIWSEPSDPLELV 1247 P +WS PSD LEL+ Sbjct: 200 SNSPYVWSLPSDLLELL 216 Score = 76.3 bits (186), Expect = 2e-13 Identities = 65/210 (30%), Positives = 96/210 (45%), Gaps = 19/210 (9%) Query: 37 QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92 +P L ++ AP E++TL C S +F+L K D Q +P Q +F Sbjct: 223 KPSLSVQPGPMVAPGESLTLQCVSDVGYD-RFVLYKEGERDFLQRPGWQPQAGLSQANFT 281 Query: 93 IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQL-PKPIFWIQAETPALPGCNVN 149 +G ++ S+ G YRC + + WS PS L++ GQ +P +Q PG NV Sbjct: 282 LGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVT 341 Query: 150 ILCHGWLQDLVFMLFKEGYAEPV-----DYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 +LC Q F+L KEG P ++Q A F + +T G Y C + + Sbjct: 342 LLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN-QAEFRMGPVTSAHVGTYRCYSSLS 400 Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP 234 P L S PS+PL+LVV+ +L HP Sbjct: 401 SNPYLLSLPSDPLELVVSA-----SLGQHP 425 Score = 74.3 bits (181), Expect = 7e-13 Identities = 64/208 (30%), Positives = 98/208 (47%), Gaps = 23/208 (11%) Query: 584 EIVMP--TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-------GWIAT 634 E+++P + KP L + +AP ++LTL C S G + FVL K+G GW Sbjct: 214 ELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDR-FVLYKEGERDFLQRPGW--- 269 Query: 635 RPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV--SEPSEALELVGT-DILPKPVISAS 691 +P + +A F LG ++ SH G Y C+S ++ S PS+ L+++ T +P +S Sbjct: 270 QPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQ 329 Query: 692 PT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGREAFFTIQRMEDKD 744 P G+ + L C+ F L KEG P L A +A F + + Sbjct: 330 PVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAH 389 Query: 745 EGNYSCRTHTEKRPFKWSEPSEPLELVI 772 G Y C + P+ S PS+PLELV+ Sbjct: 390 VGTYRCYSSLSSNPYLLSLPSDPLELVV 417 >gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 isoform a [Homo sapiens] Length = 483 Score = 201 bits (512), Expect = 3e-51 Identities = 154/445 (34%), Positives = 209/445 (46%), Gaps = 42/445 (9%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFR-SVSGNSADFLLHT 931 PKPTL A+PG V+ G V LRCQG+ Q + L +E R G + F + + Sbjct: 27 PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFPIPS 86 Query: 932 VGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991 + E +G Y C YY N S S PL + VT + KP L A PS VV +G NVTL C Sbjct: 87 ITWEHAGRYHCQYYS---HNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQC 143 Query: 992 RGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWTS 1046 V G+IL KEGE Q S S+ F + +S + Y C + + Sbjct: 144 VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDSNSP 203 Query: 1047 SIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG---- 1102 + PS+ LELLV G+ KPSL QPGPMVAPGE++TLQC ++ FVL KEG Sbjct: 204 YVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDF 263 Query: 1103 AQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDK-PP 1161 Q P Q + +A+F + V G Y C Y + S SD L+I +T + Sbjct: 264 LQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDILITGQFYD 322 Query: 1162 KPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDGDFVI 1213 +PSLS P GK++TL C+ F+L +G P Q +F + Sbjct: 323 RPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRM 382 Query: 1214 NNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-------------------GAAGPVA 1254 V +G Y C L + P + S PSDPLELV + G Sbjct: 383 GPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHP 442 Query: 1255 QECTVGNIVRSSLIVVVVVALGVVL 1279 Q+ TV N++R + +V+V LG++L Sbjct: 443 QDYTVENLIRMGVAGLVLVVLGILL 467 Score = 193 bits (491), Expect = 8e-49 Identities = 138/413 (33%), Positives = 198/413 (47%), Gaps = 25/413 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ S +E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYH 59 Query: 624 LLKDGTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682 L ++ R E + FP+ ++T H G YHC + SE S+ LELV T Sbjct: 60 LYRENKSASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119 Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGRE-----AF 734 KP +SA P+ G + L+C +A GF L KEGE E Q+L + A Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F++ + +Y C + P+ WS PS+ LEL++ + KP P+V PG Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239 Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSW-ASPGASAAHFLIISVGIGDGGNYSC--RY 851 +T C + + F+LYK+G W G S A+F + V GG Y C + Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299 Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910 S WS PSDP+++++T +FY +P+L QP P V PGK+V L CQ Q F L +EG Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359 Query: 911 A-HVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959 A H PL RS N A+F + V + G Y C +++S+ LS+P Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCY---SSLSSNPYLLSLP 409 Score = 172 bits (437), Expect = 1e-42 Identities = 148/421 (35%), Positives = 200/421 (47%), Gaps = 27/421 (6%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+ G+ VT C Q + LY++ AS R PG + F Sbjct: 27 PKPTL--WAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS-ASWVRRIQEPGKNG-QF 82 Query: 835 LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894 I S+ G Y C+YY + SE SDP+ELVVT Y KPTL A P PVV G +V L+ Sbjct: 83 PIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTLQ 142 Query: 895 C--QGTFQGMRFALLQEGA-HVPLQFRSVS----GNSADFLLHTVGAEDSGNYSCIYYET 947 C Q F G F L +EG P + S S + A F + V +Y C Y++ Sbjct: 143 CVSQVAFDG--FILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200 Query: 948 TMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE 1007 S S L + V KP L +P +V G+++TL C V ++L+KEGE Sbjct: 201 NSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGE 260 Query: 1008 ATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG- 1062 +Q G G F + +S + G+Y CY SS PS+ L++L+TG Sbjct: 261 RDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYR-CYSAHNLSSEWSAPSDPLDILITGQ 319 Query: 1063 LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRAD 1118 +PSL QP P VAPG+N+TL CQ TF+L KEGA P + + +A+ Sbjct: 320 FYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAE 379 Query: 1119 FWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD--KPPKPSLSAWPSTMFKLG 1176 F M V G Y C L S P+ S SD LE+ V++ + PS + ST LG Sbjct: 380 FRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLG 439 Query: 1177 K 1177 + Sbjct: 440 Q 440 Score = 134 bits (337), Expect = 6e-31 Identities = 120/435 (27%), Positives = 194/435 (44%), Gaps = 19/435 (4%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ S + ++ L ++ Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQG-SLQAEEYHLYRENK 65 Query: 76 QMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134 +W+R + + F I ++T +AG Y C Y+ S+ S LEL G KP Sbjct: 66 SASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGAYSKPTL 125 Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSIDNL 189 G NV + C + F+L KEG E + AIFS+ + Sbjct: 126 SALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPV 185 Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQ 249 +P Y C + P +WS PS+ L+L+V G+ KP+L+ PGP++APGESL L+C Sbjct: 186 SPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCV 245 Query: 250 GPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASYRG 305 + F L + + L++ + + ++ANF + G Y C+ ++ S Sbjct: 246 SDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEW 305 Query: 306 SLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ 364 S SD L I +T F + L +P V G+NV+L C+ L K+G P Sbjct: 306 SAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPL 365 Query: 365 FL--DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVD--KPPK 420 L + + + F + VT + G Y C+ L+ + + +EL+V + + Sbjct: 366 HLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLS 425 Query: 421 PSLSAWPSTVFKLGK 435 PS + ST LG+ Sbjct: 426 PSQNKTDSTTTSLGQ 440 Score = 121 bits (304), Expect = 4e-27 Identities = 111/406 (27%), Positives = 176/406 (43%), Gaps = 40/406 (9%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT-GTMAIFS 185 G LPKP W + + + G V + C G LQ + L++E + ++ G F Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83 Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245 I ++T E G Y C+ + SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 IPSITWEHAGRYHCQYYSHNHS---SEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140 Query: 246 LRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLCF 297 L+C + F L + + E H + + + ++ S I G Y C+ Sbjct: 141 LQCVSQVAFDGFILCKEGEDE----HPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCY 196 Query: 298 YYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALY 355 YD++ Y SL SD+L++ V K L +P +V G++++L+C V LY Sbjct: 197 AYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLY 256 Query: 356 KKGEDKPLQF--LDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELM 413 K+GE LQ + +F L V+ S G Y C+ + PS L+ Sbjct: 257 KEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILI 316 Query: 414 VVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERET 459 +PSLS P GK +TL C+ HP L E + ++ Sbjct: 317 TGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQN 376 Query: 460 FQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 +F + V GTY C + ++P + S S+PL+L+ Sbjct: 377 ------QAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELV 416 Score = 106 bits (265), Expect = 1e-22 Identities = 91/301 (30%), Positives = 129/301 (42%), Gaps = 13/301 (4%) Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTI 275 P V AG PKPTL A PG ++ G + LRCQG + + L R + Sbjct: 17 PRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEP 76 Query: 276 KNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQM 335 F S+ + G Y C YY ++ S SD L++ VT + K L A PS VV + Sbjct: 77 GKNGQFPIPSITWEHAGRYHCQYYSHNH-SSEYSDPLELVVTGAYSKPTLSALPSPVVTL 135 Query: 336 GQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSC 392 G NV+L+C V G L K+GED+ Q L++ S S F + V+ S Y C Sbjct: 136 GGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRC 195 Query: 393 HYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL 452 + + + + +EL+V KPSLS P + G+++TLQC F L Sbjct: 196 YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVL 255 Query: 453 EWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKL 504 E F Q +F + V G Y C Y + WS S+PL + Sbjct: 256 YKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLSSEWSAPSDPLDI 314 Query: 505 M 505 + Sbjct: 315 L 315 Score = 99.4 bits (246), Expect = 2e-20 Identities = 71/197 (36%), Positives = 104/197 (52%), Gaps = 15/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP-LEQQRPSGYRADFW 1120 G LPKP+L A+PG ++ G +TL+CQG L + L +E + + + G F Sbjct: 24 GHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKSASWVRRIQEPGKNGQFP 83 Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180 +P++ E +G Y C YY + +S +SD LE+ VT KP+LSA PS + LG ++T Sbjct: 84 IPSITWEHAGRYHCQYYSHN---HSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVT 140 Query: 1181 LQCRGPLPGVEFVLEHDGE-EAPQQFSEDG-----DFVINNVEGKGIGNYSCSYRLQAY- 1233 LQC + F+L +GE E PQ+ + + I +V G + SYR AY Sbjct: 141 LQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSV-GPVSPSRRWSYRCYAYD 199 Query: 1234 ---PDIWSEPSDPLELV 1247 P +WS PSD LEL+ Sbjct: 200 SNSPYVWSLPSDLLELL 216 Score = 76.3 bits (186), Expect = 2e-13 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 23/210 (10%) Query: 584 EIVMP--TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-------GWIAT 634 E+++P + KP L + +AP ++LTL C S G + FVL K+G GW Sbjct: 214 ELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDR-FVLYKEGERDFLQRPGW--- 269 Query: 635 RPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV--SEPSEALELVGT-DILPKPVISAS 691 +P + +A F LG ++ SH G Y C+S ++ S PS+ L+++ T +P +S Sbjct: 270 QPQAGLSQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQ 329 Query: 692 PT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGREAFFTIQRMEDKD 744 P G+ + L C+ F L KEG P L A +A F + + Sbjct: 330 PVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAH 389 Query: 745 EGNYSCRTHTEKRPFKWSEPSEPLELVIKE 774 G Y C + P+ S PS+PLELV+ E Sbjct: 390 VGTYRCYSSLSSNPYLLSLPSDPLELVVSE 419 Score = 64.7 bits (156), Expect = 6e-10 Identities = 56/198 (28%), Positives = 86/198 (43%), Gaps = 17/198 (8%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDD-NTSFFL 379 PK L A P +V+ G V+LRC+G + LY+ E+K ++ N F + Sbjct: 27 PKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYR--ENKSASWVRRIQEPGKNGQFPI 84 Query: 380 NNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 ++T+ G Y C Y + + + +EL+V KP+LSA PS V LG +TL Sbjct: 85 PSITWEHAGRYHCQY---YSHNHSSEYSDPLELVVTGAYSKPTLSALPSPVVTLGGNVTL 141 Query: 440 QCRVSHPVLEFSLEWEERETFQKFSVNGD----------FIISNVDGKGTGTYSCSYRVE 489 QC VS + + +E E +N F + V +Y C Sbjct: 142 QC-VSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFSVGPVSPSRRWSYRCYAYDS 200 Query: 490 THPNIWSHRSEPLKLMGP 507 P +WS S+ L+L+ P Sbjct: 201 NSPYVWSLPSDLLELLVP 218 >gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 1 [Homo sapiens] Length = 632 Score = 200 bits (508), Expect = 9e-51 Identities = 139/416 (33%), Positives = 204/416 (49%), Gaps = 32/416 (7%) Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624 +TALLC GL G T + P PKP LWAE ++ +T+WC+ S +E+ L Sbjct: 5 LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRL 60 Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682 K+G+ R P + +A F + ++T+ H G Y CH + SEPS+ LE+V T Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120 Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734 KP +SA P+ G + LRC F L KEGE + QQL + G +A Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F + + ++C + P+ WS PS+PLE++ + KP T PV+ PG Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240 Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851 +T C + + F+LYK+G + G S A+F + V +GG Y C + Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300 Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910 S WS PSDP+ +++ + Y +L AQPGP V G++V L CQ +Q F L +EG Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360 Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962 AH PL+ RS+ G A+F + V + +G Y C GSY S P ++ Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY---------GSYSSNPHLL 407 Score = 182 bits (463), Expect = 1e-45 Identities = 140/398 (35%), Positives = 191/398 (47%), Gaps = 20/398 (5%) Query: 776 YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833 +PKP WA P V++ G+ VT C + + L+K+GS DR+ + A Sbjct: 26 FPKPTL--WAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSP-EPLDRNNPLEPKNKAR 82 Query: 834 FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 F I S+ G Y C YY + WSEPSDP+E+V+T Y KPTL A P PVV G ++ L Sbjct: 83 FSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 RC F L++EG H + Q G A F + V ++C YY T Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S+ S PL I + KP L V+ GQ++TL C V ++L+KEGE Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +Q G G F + +S ++ G+Y CY SS PS+ L +L+ G + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119 SL AQPGP VA GEN+TL CQ TF+L KEGA P + R Y+A+F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 M V +G Y C S P S+ S+ LE+ V+ Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVS 419 Score = 166 bits (420), Expect = 1e-40 Identities = 127/396 (32%), Positives = 188/396 (47%), Gaps = 24/396 (6%) Query: 872 YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929 +PKPTL A+PG V+ G V + CQG+ + + L +EG+ PL + N A F + Sbjct: 26 FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85 Query: 930 HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 ++ +G Y C YY S S S PL + +T + KP L A PS VV G N+TL Sbjct: 86 PSMTEHHAGRYRCHYYS---SAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 990 WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044 C ++L KEGE Q S FP+ ++ + R++C Y+ Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103 T + PS+ LE+L +G+ KPSLL GP++APG+++TLQC ++ + FVL KEG Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160 Q P +Q + +A+F + V + G Y C Y + S SD L I + + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211 SLSA P G+++TL C+ F+L +G P +F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247 ++ V G Y C + P + S PS+PLELV Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELV 417 Score = 156 bits (394), Expect = 1e-37 Identities = 103/297 (34%), Positives = 145/297 (48%), Gaps = 19/297 (6%) Query: 968 FPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWG--STSNDGAFPI 1025 FPKP L+AEP SV+ G VT+WC+G Y LHKEG + N F I Sbjct: 26 FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85 Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085 +++ GRY C Y+ +S+ +PS+ LE+++TG KP+L A P P+VA G NMTL Sbjct: 86 PSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 1086 QCQGELPDSTFVLLKEGAQE-----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140 +C + FVL+KEG + +Q G++A F + V ++C YY + Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199 TP+ S+ SD LEI + KPSL + G+ +TLQC + FVL +GE Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249 + PQ +F + V G Y C Y WS PSDPL ++ A Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMA 318 Score = 139 bits (351), Expect = 1e-32 Identities = 110/396 (27%), Positives = 180/396 (45%), Gaps = 28/396 (7%) Query: 20 LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76 L C+ +SLG + V P+P LW E + +T+WC+ S+ + ++ L K+ + Sbjct: 8 LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRLHKEGSP 66 Query: 77 MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134 R P + F I ++TE +AG YRC Y+ GWS+PS LE+ G KP Sbjct: 67 EPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTL 126 Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184 G N+ + C F+L KEG ++Q+P G A+F Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSRGFQALF 181 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 + +TP + C + P +WS PS+PL+++ +G+ KP+L GP++APG+SL Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241 Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300 L+C + F L + + L++ + ++ANF + + G Y C+ ++ Sbjct: 242 TLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHN 301 Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359 S S SD L I + + L A+P V G+NV+L C+ L K+G Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGA 361 Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393 P L + + F ++ VT + G Y C+ Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397 Score = 136 bits (342), Expect = 2e-31 Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 54/455 (11%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184 G PKP W + + G V I C G + + L KEG EP+D P A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 SI ++T G Y C + WSEPS+PL++V+ G Y KPTL+A P P++A G ++ Sbjct: 84 SIPSMTEHHAGRYRCHYYSS---AGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140 Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298 LRC F LM+ + L+ H + +A F + + C+Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGF--QALFPVGPVTPSHRWRFTCYY 198 Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 Y + + S SD L+I + K LL V+ GQ+++L+C V LYK Sbjct: 199 YYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYK 258 Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 +GE +P Q A N F L V+ S+ G Y C+ + PS L Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNIL 316 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458 M SLSA P G+ +TL C+ +HP L R Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRL------RS 370 Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM------------- 505 + +F +S V GTY C ++P++ SH SEPL+L+ Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPT 430 Query: 506 GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540 GP L I +S+ L+ LL+ L +R Sbjct: 431 GPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465 Score = 99.0 bits (245), Expect = 3e-20 Identities = 67/197 (34%), Positives = 98/197 (49%), Gaps = 14/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G PKP+L A+PG +++ G +T+ CQG + L KEG+ EPL++ P +A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ +G Y C YY + S SD LE+ +T KP+LSA PS + G ++ Sbjct: 84 SIPSMTEHHAGRYRCHYYSSA---GWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140 Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230 TL+C FVL +GE QQ G F + V ++C Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYY 200 Query: 1231 QAYPDIWSEPSDPLELV 1247 P +WS PSDPLE++ Sbjct: 201 TNTPWVWSHPSDPLEIL 217 Score = 76.6 bits (187), Expect = 1e-13 Identities = 64/196 (32%), Positives = 87/196 (44%), Gaps = 15/196 (7%) Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQV----RAAFP 646 KP L LAP ++LTL C S G + FVL K+G RP + +A F Sbjct: 224 KPSLLTLQGPVLAPGQSLTLQCGSDVGYNR-FVLYKEGERDFLQRPGQQPQAGLSQANFT 282 Query: 647 LGALTQSHTGSYHCHSWEEMAV--SEPSEALE-LVGTDILPKPVISASP---TIRGQELQ 700 LG ++ S+ G Y C+ ++ S PS+ L L+ I +SA P G+ + Sbjct: 283 LGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVT 342 Query: 701 LRCKGWLAGMGFALYKEGEQEPVQQL----GAVGREAFFTIQRMEDKDEGNYSCRTHTEK 756 L C+ W F L KEG P +L GA +A F + + G Y C Sbjct: 343 LLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSS 402 Query: 757 RPFKWSEPSEPLELVI 772 P S PSEPLELV+ Sbjct: 403 NPHLLSHPSEPLELVV 418 >gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B, member 3 isoform 2 [Homo sapiens] Length = 631 Score = 200 bits (508), Expect = 9e-51 Identities = 139/416 (33%), Positives = 204/416 (49%), Gaps = 32/416 (7%) Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624 +TALLC GL G T + P PKP LWAE ++ +T+WC+ S +E+ L Sbjct: 5 LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRL 60 Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682 K+G+ R P + +A F + ++T+ H G Y CH + SEPS+ LE+V T Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120 Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734 KP +SA P+ G + LRC F L KEGE + QQL + G +A Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F + + ++C + P+ WS PS+PLE++ + KP T PV+ PG Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240 Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851 +T C + + F+LYK+G + G S A+F + V +GG Y C + Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300 Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910 S WS PSDP+ +++ + Y +L AQPGP V G++V L CQ +Q F L +EG Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360 Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962 AH PL+ RS+ G A+F + V + +G Y C GSY S P ++ Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY---------GSYSSNPHLL 407 Score = 182 bits (463), Expect = 1e-45 Identities = 140/398 (35%), Positives = 191/398 (47%), Gaps = 20/398 (5%) Query: 776 YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833 +PKP WA P V++ G+ VT C + + L+K+GS DR+ + A Sbjct: 26 FPKPTL--WAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSP-EPLDRNNPLEPKNKAR 82 Query: 834 FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 F I S+ G Y C YY + WSEPSDP+E+V+T Y KPTL A P PVV G ++ L Sbjct: 83 FSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 RC F L++EG H + Q G A F + V ++C YY T Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S+ S PL I + KP L V+ GQ++TL C V ++L+KEGE Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +Q G G F + +S ++ G+Y CY SS PS+ L +L+ G + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119 SL AQPGP VA GEN+TL CQ TF+L KEGA P + R Y+A+F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 M V +G Y C S P S+ S+ LE+ V+ Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVS 419 Score = 166 bits (420), Expect = 1e-40 Identities = 127/396 (32%), Positives = 188/396 (47%), Gaps = 24/396 (6%) Query: 872 YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929 +PKPTL A+PG V+ G V + CQG+ + + L +EG+ PL + N A F + Sbjct: 26 FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85 Query: 930 HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 ++ +G Y C YY S S S PL + +T + KP L A PS VV G N+TL Sbjct: 86 PSMTEHHAGRYRCHYYS---SAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 990 WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044 C ++L KEGE Q S FP+ ++ + R++C Y+ Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103 T + PS+ LE+L +G+ KPSLL GP++APG+++TLQC ++ + FVL KEG Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160 Q P +Q + +A+F + V + G Y C Y + S SD L I + + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211 SLSA P G+++TL C+ F+L +G P +F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247 ++ V G Y C + P + S PS+PLELV Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELV 417 Score = 156 bits (394), Expect = 1e-37 Identities = 103/297 (34%), Positives = 145/297 (48%), Gaps = 19/297 (6%) Query: 968 FPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWG--STSNDGAFPI 1025 FPKP L+AEP SV+ G VT+WC+G Y LHKEG + N F I Sbjct: 26 FPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSI 85 Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085 +++ GRY C Y+ +S+ +PS+ LE+++TG KP+L A P P+VA G NMTL Sbjct: 86 PSMTEHHAGRYRCHYY---SSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTL 142 Query: 1086 QCQGELPDSTFVLLKEGAQE-----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140 +C + FVL+KEG + +Q G++A F + V ++C YY + Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199 TP+ S+ SD LEI + KPSL + G+ +TLQC + FVL +GE Sbjct: 203 TPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGER 262 Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249 + PQ +F + V G Y C Y WS PSDPL ++ A Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRC-YGAHNLSSEWSAPSDPLNILMA 318 Score = 139 bits (351), Expect = 1e-32 Identities = 110/396 (27%), Positives = 180/396 (45%), Gaps = 28/396 (7%) Query: 20 LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76 L C+ +SLG + V P+P LW E + +T+WC+ S+ + ++ L K+ + Sbjct: 8 LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SQEAQEYRLHKEGSP 66 Query: 77 MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134 R P + F I ++TE +AG YRC Y+ GWS+PS LE+ G KP Sbjct: 67 EPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTL 126 Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184 G N+ + C F+L KEG ++Q+P G A+F Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSRGFQALF 181 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 + +TP + C + P +WS PS+PL+++ +G+ KP+L GP++APG+SL Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241 Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300 L+C + F L + + L++ + ++ANF + + G Y C+ ++ Sbjct: 242 TLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHN 301 Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359 S S SD L I + + L A+P V G+NV+L C+ L K+G Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGA 361 Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393 P L + + F ++ VT + G Y C+ Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 397 Score = 136 bits (342), Expect = 2e-31 Identities = 130/455 (28%), Positives = 188/455 (41%), Gaps = 54/455 (11%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184 G PKP W + + G V I C G + + L KEG EP+D P A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 SI ++T G Y C + WSEPS+PL++V+ G Y KPTL+A P P++A G ++ Sbjct: 84 SIPSMTEHHAGRYRCHYYSS---AGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140 Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298 LRC F LM+ + L+ H + +A F + + C+Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGF--QALFPVGPVTPSHRWRFTCYY 198 Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 Y + + S SD L+I + K LL V+ GQ+++L+C V LYK Sbjct: 199 YYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYK 258 Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 +GE +P Q A N F L V+ S+ G Y C+ + PS L Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNIL 316 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458 M SLSA P G+ +TL C+ +HP L R Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRL------RS 370 Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM------------- 505 + +F +S V GTY C ++P++ SH SEPL+L+ Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPT 430 Query: 506 GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIR 540 GP L I +S+ L+ LL+ L +R Sbjct: 431 GPPSTPGLGRYLEVLIGVSVAFVLLLFLLLFLLLR 465 Score = 99.0 bits (245), Expect = 3e-20 Identities = 67/197 (34%), Positives = 98/197 (49%), Gaps = 14/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G PKP+L A+PG +++ G +T+ CQG + L KEG+ EPL++ P +A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ +G Y C YY + S SD LE+ +T KP+LSA PS + G ++ Sbjct: 84 SIPSMTEHHAGRYRCHYYSSA---GWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNM 140 Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230 TL+C FVL +GE QQ G F + V ++C Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYY 200 Query: 1231 QAYPDIWSEPSDPLELV 1247 P +WS PSDPLE++ Sbjct: 201 TNTPWVWSHPSDPLEIL 217 Score = 76.6 bits (187), Expect = 1e-13 Identities = 64/196 (32%), Positives = 87/196 (44%), Gaps = 15/196 (7%) Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQV----RAAFP 646 KP L LAP ++LTL C S G + FVL K+G RP + +A F Sbjct: 224 KPSLLTLQGPVLAPGQSLTLQCGSDVGYNR-FVLYKEGERDFLQRPGQQPQAGLSQANFT 282 Query: 647 LGALTQSHTGSYHCHSWEEMAV--SEPSEALE-LVGTDILPKPVISASP---TIRGQELQ 700 LG ++ S+ G Y C+ ++ S PS+ L L+ I +SA P G+ + Sbjct: 283 LGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVT 342 Query: 701 LRCKGWLAGMGFALYKEGEQEPVQQL----GAVGREAFFTIQRMEDKDEGNYSCRTHTEK 756 L C+ W F L KEG P +L GA +A F + + G Y C Sbjct: 343 LLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSS 402 Query: 757 RPFKWSEPSEPLELVI 772 P S PSEPLELV+ Sbjct: 403 NPHLLSHPSEPLELVV 418 >gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A, member 6 [Homo sapiens] Length = 481 Score = 196 bits (498), Expect = 1e-49 Identities = 140/419 (33%), Positives = 204/419 (48%), Gaps = 23/419 (5%) Query: 566 VTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVL 624 +TALLC GL G T + P PKP LWAE ++ +T+WC+ S +E+ L Sbjct: 5 LTALLCLGLSLG---PRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SLEAQEYQL 60 Query: 625 LKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDI 682 K+G+ R P + +A F + ++TQ H G Y CH + SEPS+ LELV T Sbjct: 61 DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120 Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQE-----PVQQLGAVGREAF 734 KP +SA P+ G + LRC F L KEGE + QQL + G +A Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F + + ++C + P WS PS+PLE++ + KP T PV+ PG Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240 Query: 795 VTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC--RY 851 +T C + + F+LYK+G + G S A+F + V GG Y C + Sbjct: 241 LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH 300 Query: 852 YDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG 910 S WS PSDP+ +++ + Y +L AQPGP V G++V L CQ F L +EG Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEG 360 Query: 911 -AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965 AH PL+ RS+ G A+F + V + +G Y C ++ + S+ S PL + V+ Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVS 419 Score = 187 bits (475), Expect = 6e-47 Identities = 150/425 (35%), Positives = 200/425 (47%), Gaps = 22/425 (5%) Query: 776 YPKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAH 833 +PKP WA P V++ G+ VT C + + L K+GS DR+ + A Sbjct: 26 FPKPTL--WAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSP-EPLDRNNPLEPKNKAR 82 Query: 834 FLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 F I S+ G Y C YY + WSEPSDP+ELV+T FY KPTL A P PVV G ++ L Sbjct: 83 FSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTL 142 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 RC F L++EG H + Q G A F + V ++C YY T Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S+ S PL I + KP L V+ GQ++TL C V ++L+KEGE Sbjct: 203 TPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGER 262 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +Q G G F + +S + G+Y CY SS PS+ L +L+ G + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYR-CYGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQR----PSGYRADF 1119 SL AQPGP VA GEN+TL CQ TF+L KEGA P + R Y+A+F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSL--SAWPSTMFKLGK 1177 M V +G Y C S P S S+ LE+ V+ SL + PST K Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAK 441 Query: 1178 DITLQ 1182 D T++ Sbjct: 442 DYTVE 446 Score = 171 bits (432), Expect = 6e-42 Identities = 138/444 (31%), Positives = 209/444 (47%), Gaps = 40/444 (9%) Query: 872 YPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV--SGNSADFLL 929 +PKPTL A+PG V+ G V + CQG+ + + L +EG+ PL + N A F + Sbjct: 26 FPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARFSI 85 Query: 930 HTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 ++ +G Y C YY S S S PL + +T + KP L A PS VV G N+TL Sbjct: 86 PSMTQHHAGRYRCHYYS---SAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTL 142 Query: 990 WCRGPVHGVGYILHKEGE-----ATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDW 1044 C ++L KEGE Q S FP+ ++ + R++C Y+ Sbjct: 143 RCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTN 202 Query: 1045 TSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGA- 1103 T + PS+ LE+L +G+ KPSLL GP++APG+++TLQC ++ FVL KEG Sbjct: 203 TPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGER 262 Query: 1104 ---QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKP 1160 Q P +Q + +A+F + V G Y C Y + S SD L I + + Sbjct: 263 DFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRC-YGAHNLSSEWSAPSDPLNILMAGQI 321 Query: 1161 -PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ--------QFSEDGDF 1211 SLSA P G+++TL C+ F+L +G P +F Sbjct: 322 YDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEF 381 Query: 1212 VINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV------GAAGPV----------AQ 1255 ++ V G Y C + P + S PS+PLEL+ G++ P A+ Sbjct: 382 PMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAK 441 Query: 1256 ECTVGNIVRSSLIVVVVVALGVVL 1279 + TV N++R + +V+V LG++L Sbjct: 442 DYTVENLIRMGMAGLVLVFLGILL 465 Score = 136 bits (342), Expect = 2e-31 Identities = 121/445 (27%), Positives = 195/445 (43%), Gaps = 30/445 (6%) Query: 20 LFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQ 76 L C+ +SLG + V P+P LW E + +T+WC+ S + ++ L K+ + Sbjct: 8 LLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQG-SLEAQEYQLDKEGSP 66 Query: 77 MTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIF 134 R P + F I ++T+ +AG YRC Y+ GWS+PS LEL G KP Sbjct: 67 EPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGFYNKPTL 126 Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT----------GTMAIF 184 G N+ + C F+L KEG ++Q+P G A+F Sbjct: 127 SALPSPVVASGGNMTLRCGSQKGYHHFVLMKEG-----EHQLPRTLDSQQLHSGGFQALF 181 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 + +TP + C + P +WS PS+PL+++ +G+ KP+L GP++APG+SL Sbjct: 182 PVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSL 241 Query: 245 NLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYD 300 L+C + F L + + L++ + ++ANF + G Y C+ ++ Sbjct: 242 TLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHN 301 Query: 301 ASYRGSLLSDVLKIWVT-DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359 S S SD L I + + L A+P V G+NV+L C+ L K+G Sbjct: 302 LSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGA 361 Query: 360 DKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDK 417 P L + + F ++ VT + G Y C+ + + +ELMV Sbjct: 362 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGH 421 Query: 418 PPKPSL--SAWPSTVFKLGKAITLQ 440 SL + PST K T++ Sbjct: 422 SGGSSLPPTGPPSTPASHAKDYTVE 446 Score = 132 bits (331), Expect = 3e-30 Identities = 122/407 (29%), Positives = 170/407 (41%), Gaps = 41/407 (10%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTG--TMAIF 184 G PKP W + + G V I C G L+ + L KEG EP+D P A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 SI ++T G Y C + WSEPS+PL+LV+ G Y KPTL+A P P++A G ++ Sbjct: 84 SIPSMTQHHAGRYRCHYYSS---AGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNM 140 Query: 245 NLRCQGPIYGMTFALMRVED------LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFY 298 LRC F LM+ + L+ H +A F + + C+Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGF--QALFPVGPVTPSHRWRFTCYY 198 Query: 299 Y--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 Y + S SD L+I + K LL V+ GQ+++L+C V LYK Sbjct: 199 YYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYK 258 Query: 357 KGE----DKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 +GE +P Q A N F L V+ S G Y C+ + PS L Sbjct: 259 EGERDFLQRPGQQPQAGLSQAN--FTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPLNIL 316 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCR--------------VSHPVLEFSLEWEERE 458 M SLSA P G+ +TL C+ +HP L R Sbjct: 317 MAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRL------RS 370 Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 + +F +S V GTY C ++P++ S SEPL+LM Sbjct: 371 MYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELM 417 Score = 101 bits (252), Expect = 4e-21 Identities = 68/197 (34%), Positives = 99/197 (50%), Gaps = 14/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G PKP+L A+PG +++ G +T+ CQG L + L KEG+ EPL++ P +A F Sbjct: 24 GPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPLDRNNPLEPKNKARF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ +G Y C YY + S SD LE+ +T KP+LSA PS + G ++ Sbjct: 84 SIPSMTQHHAGRYRCHYYSSA---GWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNM 140 Query: 1180 TLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGD---FVINNVEGKGIGNYSCSYRL 1230 TL+C FVL +GE QQ G F + V ++C Y Sbjct: 141 TLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYY 200 Query: 1231 QAYPDIWSEPSDPLELV 1247 P +WS PSDPLE++ Sbjct: 201 TNTPRVWSHPSDPLEIL 217 >gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens] Length = 495 Score = 184 bits (468), Expect = 4e-46 Identities = 159/511 (31%), Positives = 236/511 (46%), Gaps = 31/511 (6%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKE 621 M +V LL G+ G + E + +P LWAE+ L P N+TL C++ T + Sbjct: 1 MSMLVVFLLLWGVTWGPVTEAA--IFYETQPSLWAESESLLKPLANVTLTCQAHL-ETPD 57 Query: 622 FVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTD 681 F L K+G S ++ F L TQ G Y C S ++ S+ LEL G Sbjct: 58 FQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQ---GRYRCRSGLSTGWTQLSKLLELTGPK 114 Query: 682 ILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGA-VGREAFFTI 737 LP P +S +P G + C+G L G+ F L +EG+ E ++ A EA F + Sbjct: 115 SLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV 174 Query: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTW--ASPVVTPGARV 795 + GNYSC T+ SEPS + + P P +S V+ PG +V Sbjct: 175 HQ-----PGNYSCSYRTDGEG-ALSEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKV 228 Query: 796 TFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--- 852 T C P + F L + E+ RS SP F + +V +GDGG+Y+CRY Sbjct: 229 TLTCVAPLSGVDFQLRRGEKELL-VPRSSTSP--DRIFFHLNAVALGDGGHYTCRYRLHD 285 Query: 853 DFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-- 909 + + WS S PVEL+++ E P P +P G+++ LRC +G RFAL++E Sbjct: 286 NQNGWSGDSAPVELILSDETLPAPEFSPEPE----SGRALRLRCLAPLEGARFALVREDR 341 Query: 910 GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFP 969 G +F+S +G A F LH + DS NYSC+Y + GS S L + V P Sbjct: 342 GGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPP 401 Query: 970 KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029 +P L A S V G++ L C GP+ V + L +EGE +++ + + + Sbjct: 402 RPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVG 461 Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLV 1060 G Y C Y + + + S+ +ELLV Sbjct: 462 PQHAGNYRCRYRSWVPHTFESELSDPVELLV 492 Score = 152 bits (383), Expect = 3e-36 Identities = 151/480 (31%), Positives = 209/480 (43%), Gaps = 32/480 (6%) Query: 784 WASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGI 841 WA ++ P A VT C + F L+K+G +A SP A FL+ Sbjct: 32 WAESESLLKPLANVTLTCQAHLETPDFQLFKNG--VAQEPVHLDSP-AIKHQFLLT---- 84 Query: 842 GDG-GNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQ 900 GD G Y CR + W++ S +EL + P P L P + PG C+G + Sbjct: 85 GDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLR 144 Query: 901 GMRFALLQEGAHVPLQFRSVSGN-SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959 G+ F L +EG H L+ + A F +H GNYSC Y T S S Sbjct: 145 GVTFLLRREGDHEFLEVPEAQEDVEATFPVH-----QPGNYSCSY-RTDGEGALSEPSAT 198 Query: 960 LMIWVTDTFPKPWLF--AEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGST 1017 + I P P L E S V+ G VTL C P+ GV + L + GE + ST Sbjct: 199 VTIEELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRR-GEKELLVPRSST 257 Query: 1018 SNDGAFPITN-ISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-LLPKPSLLAQPGP 1075 S D F N ++ G Y+C Y + S +EL+++ LP P +P Sbjct: 258 SPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEP-- 315 Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKE--GAQEPLEQQRPSGYRADFWMPAVRGEDSGIYS 1133 G + L+C L + F L++E G + Q P+G A F + + DS YS Sbjct: 316 --ESGRALRLRCLAPLEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYS 373 Query: 1134 CVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFV 1193 CVY PF S S+ LE+ V PP+P L A S G+D L+C GP+P V F Sbjct: 374 CVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFE 433 Query: 1194 LEHDGE-EAPQQFSEDG---DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGA 1249 L +GE +A + G + + V + GNY C YR SE SDP+EL+ A Sbjct: 434 LLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVA 493 Score = 141 bits (356), Expect = 4e-33 Identities = 132/469 (28%), Positives = 196/469 (41%), Gaps = 32/469 (6%) Query: 701 LRCKGWLAGMGFALYKEG-EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPF 759 L C+ L F L+K G QEPV + F + +G Y CR+ Sbjct: 47 LTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFL----LTGDTQGRYRCRSGLSTG-- 100 Query: 760 KWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIAS 819 W++ S+ LEL + P P+ +TPG + T C + ++F+L ++G Sbjct: 101 -WTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREG----- 154 Query: 820 SDRSWASPGASAAHFLIISVGIGDGGNYSCRYY--DFSIWSEPSDPVELVVTEFYPKPTL 877 D + A + + + GNYSC Y SEPS V + P P L Sbjct: 155 -DHEFLEV-PEAQEDVEATFPVHQPGNYSCSYRTDGEGALSEPSATVTIEELAAPPPPVL 212 Query: 878 L--AQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAE 935 + + V+ PG V L C G+ F L + + + S S + F L+ V Sbjct: 213 MHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALG 272 Query: 936 DSGNYSCIYYETTMSNRGSYLSMPLMIWVTD-TFPKPWLFAEPSSVVPMGQNVTLWCRGP 994 D G+Y+C Y N S S P+ + ++D T P P EP S G+ + L C P Sbjct: 273 DGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPES----GRALRLRCLAP 328 Query: 995 VHGVGYILHKE--GEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCY---HPDWTSSIK 1049 + G + L +E G + + F + NIS YSC Y P + S Sbjct: 329 LEGARFALVREDRGGRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGS-- 386 Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109 PS LEL V G P+P L A V G + L+C+G +PD TF LL+EG + ++ Sbjct: 387 -APSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKT 445 Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158 R G A+ + V + +G Y C Y S SD +E+ V + Sbjct: 446 VRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAE 494 Score = 136 bits (343), Expect = 1e-31 Identities = 132/509 (25%), Positives = 201/509 (39%), Gaps = 33/509 (6%) Query: 11 TMLKTFTVLLFCIRMSLGMTSIVMDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLL 70 +ML F +L + +I + QP LW ES P N+TL C++ + F L Sbjct: 2 SMLVVFLLLWGVTWGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLE-TPDFQL 60 Query: 71 LKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLP 130 K+ + + FL LT G YRC TGW++ SK+LEL P LP Sbjct: 61 FKNGVAQEPVHLDSPAIKHQFL---LTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLP 117 Query: 131 KPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-QVPTGTMAIFSIDNL 189 P + + PG +C G L+ + F+L +EG E ++ + A F + Sbjct: 118 APWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPV--- 174 Query: 190 TPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAH--PGPIMAPGESLNLR 247 G Y C L SEPS + + P P L H ++ PG + L Sbjct: 175 --HQPGNYSCSYRTDGEGAL-SEPSATVTIEELAAPPPPVLMHHGESSQVLHPGNKVTLT 231 Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSL 307 C P+ G+ F L R E E T + F ++ + D GHY C Y Sbjct: 232 CVAPLSGVDFQLRRGEK-ELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRY--------R 282 Query: 308 LSDVLKIWVTDTFPKTWLLARP-------SAVVQMGQNVSLRCRGPVDGVGLALYKKGED 360 L D W D+ P +L+ S + G+ + LRC P++G AL ++ Sbjct: 283 LHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRLRCLAPLEGARFALVREDRG 342 Query: 361 KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPK 420 + F L+N++ +D+ YSC Y+ +EL V PP+ Sbjct: 343 GRRVHRFQSPAGTEALFELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPR 402 Query: 421 PSLSAWPSTVFKLGKAITLQCRVSHPVLEFSL----EWEERETFQKFSVNGDFIISNVDG 476 P L A S G+ L+C P + F L E + +T + + + V Sbjct: 403 PQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGP 462 Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 + G Y C YR S S+P++L+ Sbjct: 463 QHAGNYRCRYRSWVPHTFESELSDPVELL 491 Score = 121 bits (304), Expect = 4e-27 Identities = 103/358 (28%), Positives = 157/358 (43%), Gaps = 22/358 (6%) Query: 622 FVLLKDGTGWIATRP-ASEQVRAAFPLGALTQSHTGSYHC--HSWEEMAVSEPSEALELV 678 F+L ++G P A E V A FP+ G+Y C + E A+SEPS + + Sbjct: 148 FLLRREGDHEFLEVPEAQEDVEATFPV-----HQPGNYSCSYRTDGEGALSEPSATVTIE 202 Query: 679 GTDILPKPVI-----SASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREA 733 P PV+ S+ G ++ L C L+G+ F L + ++ V + Sbjct: 203 ELAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRI 262 Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIK-EMYPKPFFKTWASPVVTPG 792 FF + + D G+Y+CR WS S P+EL++ E P P F SP G Sbjct: 263 FFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEF----SPEPESG 318 Query: 793 ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852 + C P + F L ++ R + SP + A F + ++ + D NYSC Y Sbjct: 319 RALRLRCLAPLEGARFALVREDRGGRRVHR-FQSPAGTEALFELHNISVADSANYSCVYV 377 Query: 853 DFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909 D S PS+ +EL V P+P L A V G+ +LRC+G + F LL+E Sbjct: 378 DLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRDAVLRCEGPIPDVTFELLRE 437 Query: 910 GAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDT 967 G ++ G +A+ L VG + +GNY C Y S LS P+ + V ++ Sbjct: 438 GETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPHTFESELSDPVELLVAES 495 Score = 70.9 bits (172), Expect = 8e-12 Identities = 61/188 (32%), Positives = 83/188 (44%), Gaps = 9/188 (4%) Query: 1066 KPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG-AQEPLEQQRPSGYRADFWMPAV 1124 +PSL A+ ++ P N+TL CQ L F L K G AQEP+ P+ + F + Sbjct: 28 QPSLWAESESLLKPLANVTLTCQAHLETPDFQLFKNGVAQEPVHLDSPA-IKHQF---LL 83 Query: 1125 RGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCR 1184 G+ G Y C L + + S LE+ P P LS P + G T CR Sbjct: 84 TGDTQGRYRCRSGLST---GWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCR 140 Query: 1185 GPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPL 1244 G L GV F+L +G+ + E + V GNYSCSYR + SEPS + Sbjct: 141 GVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNYSCSYRTDGEGAL-SEPSATV 199 Query: 1245 ELVGAAGP 1252 + A P Sbjct: 200 TIEELAAP 207 Score = 52.4 bits (124), Expect = 3e-06 Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 3/135 (2%) Query: 91 FLIGALTESNAGLYRCCYWK---ETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCN 147 F + ++ +++ Y C Y G S PS+ LEL G P+P L G + Sbjct: 359 FELHNISVADSANYSCVYVDLKPPFGGSAPSERLELHVDGPPPRPQLRATWSGAVLAGRD 418 Query: 148 VNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLP 207 + C G + D+ F L +EG + V G A + + P+ G Y CR + Sbjct: 419 AVLRCEGPIPDVTFELLREGETKAVKTVRTPGAAANLELIFVGPQHAGNYRCRYRSWVPH 478 Query: 208 TLWSEPSNPLKLVVA 222 T SE S+P++L+VA Sbjct: 479 TFESELSDPVELLVA 493 >gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 1 [Homo sapiens] Length = 591 Score = 182 bits (461), Expect = 2e-45 Identities = 146/421 (34%), Positives = 194/421 (46%), Gaps = 27/421 (6%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+ G VT C P + + L K+G A ++ PGA A F Sbjct: 27 PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83 Query: 835 LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894 I S G Y C Y + WSEPSDP+ELV T FY +PTLLA P PVV G +V L+ Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQ 143 Query: 895 CQGTFQGMRFALLQEGAHVPLQFRS----VSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950 C + F L++E +P S + A F + V + C YY Sbjct: 144 CDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNP 203 Query: 951 NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS 1010 S S L I V KP L SVV G ++TL CR V ++L+KEGE Sbjct: 204 QVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDL 263 Query: 1011 MQLWGSTSNDGA----FPITNISGTSMGRYSCC----YHPDWTSSIKIQPSNTLELLVTG 1062 +Q G G F + +S + G+Y C P W++ PS+ L++L+ G Sbjct: 264 VQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSA-----PSDPLDILIAG 318 Query: 1063 LLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRA 1117 L+P P+L QPGP VA GEN+TL CQ TF L KEGA P + + ++A Sbjct: 319 LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378 Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGK 1177 +F M V G Y C + S P+ S+ S E+ V+ PSLS ST G Sbjct: 379 EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAGP 438 Query: 1178 D 1178 + Sbjct: 439 E 439 Score = 164 bits (414), Expect = 7e-40 Identities = 138/460 (30%), Positives = 203/460 (44%), Gaps = 27/460 (5%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620 M ++ L+C GL G T + T PKP LWAE +A K +TLWC+ P T+ Sbjct: 1 MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56 Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678 E+ L K+G W R P +A F + + G Y C+ SEPS+ LELV Sbjct: 57 EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 679 GTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP----VQQLGAVGR 731 T +P + A P+ G + L+C + F L +E ++ P Q+L Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176 Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTP 791 +A F + + + C + K P WS PS+ LE+++ + KP VV Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236 Query: 792 GARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850 G +T C + + F+LYK+G ++ G S A+F + V GG Y C Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295 Query: 851 YYDFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906 Y ++ WS PSDP+++++ P P L QPGP V G++V L CQ Q F L Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355 Query: 907 LQEG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962 +EG AH PL +S + A+F + V + G Y C + S S P + Sbjct: 356 TKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQEL 415 Query: 963 WVTDTFPKPWLFAEPSSVVPMG---QNVTLWCRGPVHGVG 999 V+ P L S+ P G Q +T P G+G Sbjct: 416 VVSGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLG 455 Score = 152 bits (385), Expect = 2e-36 Identities = 128/403 (31%), Positives = 189/403 (46%), Gaps = 32/403 (7%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926 PKPTL A+P V+ GK V L CQG + + L +EG PL+ G A Sbjct: 27 PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + + + +G Y C YYET S S PL + T + +P L A PS VV G N Sbjct: 83 FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGFYAEPTLLALPSPVVASGGN 139 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHP 1042 VTL C + ++L +E + L+ G FP+ ++ + R+ C Y+ Sbjct: 140 VTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYY 199 Query: 1043 DWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG 1102 + PS+ LE+LV G+ KPSLL G +VA G ++TLQC+ ++ FVL KEG Sbjct: 200 RKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEG 259 Query: 1103 AQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158 + ++ QQ +G +A+F + V G Y C + +P S SD L+I + Sbjct: 260 EHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 318 Query: 1159 KPPK-PSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDG 1209 P P+LS P G+++TL C+ F L +G P Q + Sbjct: 319 LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378 Query: 1210 DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F ++ V G Y C +++YP + S PS P ELV +GP Sbjct: 379 EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSGP 420 Score = 144 bits (364), Expect = 4e-34 Identities = 109/295 (36%), Positives = 142/295 (48%), Gaps = 18/295 (6%) Query: 967 TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG--EATSMQLWGSTSNDGAFP 1024 T PKP L+AEP+SV+ G+ VTLWC+GP+ Y L KEG A Q F Sbjct: 25 TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84 Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084 I + S GRY C Y T + +PS+ LEL+ TG +P+LLA P P+VA G N+T Sbjct: 85 IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVT 141 Query: 1085 LQCQGELPDSTFVLLKEGAQEP---LEQQRPSG-YRADFWMPAVRGEDSGIYSCVYYLDS 1140 LQC TFVL++E + P Q+ P G +A F + V + C YY Sbjct: 142 LQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRK 201 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199 P SN SD LEI V KPSL ++ G +TLQCR + FVL +GE Sbjct: 202 NPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH 261 Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247 + PQ +F + V G Y C Y WS PSDPL+++ Sbjct: 262 DLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDIL 315 Score = 142 bits (359), Expect = 2e-33 Identities = 129/409 (31%), Positives = 177/409 (43%), Gaps = 30/409 (7%) Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733 LPKP + A P RG+ + L C+G L + L KEG Q P++ G +A Sbjct: 26 LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81 Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793 F I G Y C T P WSEPS+PLELV Y +P SPVV G Sbjct: 82 KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGG 138 Query: 794 RVTFNCSTPHQHMSFILYKDGSEIASSDRSWASP-GASAAHFLIISVGIGDGGNYSCRYY 852 VT C T ++F+L ++ ++ + S P G S A F + V + C YY Sbjct: 139 NVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY 198 Query: 853 ---DFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909 + +WS PSD +E++V KP+LL G VV G S+ L+C+ F L +E Sbjct: 199 YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKE 258 Query: 910 GAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965 G H +Q + A+F L V G Y C Y +S R S S PL I + Sbjct: 259 GEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILIA 317 Query: 966 DTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA----TSMQLWGSTSND 1020 P P L +P V G+NVTL C+ + L KEG A + S + Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377 Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSL 1069 F ++ ++ G Y C + PS EL+V+G PSL Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSL 426 Score = 138 bits (347), Expect = 4e-32 Identities = 126/437 (28%), Positives = 195/437 (44%), Gaps = 24/437 (5%) Query: 12 MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68 M T +VL+ C+ +S+G + V P+P LW E A + +TLWC+ P Sbjct: 1 MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59 Query: 69 LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124 L DK + W R P + F I + +AG YRC Y GWS+PS LEL Sbjct: 60 L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEP---VDYQVPTG-T 180 A G +P G NV + C L F+L +E P ++P G + Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240 A+F + +TP + C + + P +WS PS+ L+++V G+ KP+L G ++A Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236 Query: 241 GESLNLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297 G SL L+C+ + F L + + ++ S + ++ANF + G Y C+ Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296 Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLA-RPSAVVQMGQNVSLRCRGPVDGVGLALY 355 ++ S R S SD L I + P L+ +P V G+NV+L C+ L Sbjct: 297 GAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLT 356 Query: 356 KKGEDKPLQFLDA--TSIDDNTSFFLNNVTYSDTGIYSCHYLL-TWKTSIRMPSHNTVEL 412 K+G P L + S F ++ VT + G Y C+ + ++ + PS+ EL Sbjct: 357 KEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY-PQEL 415 Query: 413 MVVDKPPKPSLSAWPST 429 +V PSLS ST Sbjct: 416 VVSGPSGDPSLSPTGST 432 Score = 137 bits (344), Expect = 9e-32 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 28/405 (6%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIF 184 G LPKP W + + G V + C G L+ + L KEG +A + G A F Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I + + G Y C P WSEPS+PL+LV G Y +PTL A P P++A G ++ Sbjct: 84 HIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140 Query: 245 NLRCQGPIYGMTFALMRVED-LEKSFYHKKTIKNEANFFFQSLKIQDT--GHYLCFYYDA 301 L+C +TF L+ E L ++ Y +K K + F + + + C+YY Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY-- 198 Query: 302 SYR-----GSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 YR S SD+L+I V K LL +VV G +++L+CR V LYK Sbjct: 199 -YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257 Query: 357 KGEDKPLQ--FLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 +GE +Q + +F L V+ S G Y C+ PS L+ Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIA 317 Query: 415 VDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVN 466 P P+LS P G+ +TL C+ H + F L E + +Q + Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377 Query: 467 GDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F +S V GTY C + ++P + S S P +L+ GP+G Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 422 Score = 94.4 bits (233), Expect = 7e-19 Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 13/196 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G LPKP+L A+P ++A G+ +TL CQG L + L KEG ++Q P G +A F Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P+ + +G Y C Y TP S SD LE+ T +P+L A PS + G ++ Sbjct: 84 HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140 Query: 1180 TLQCRGPLPGVEFVLEHDGEEAPQQF--------SEDGDFVINNVEGKGIGNYSCSYRLQ 1231 TLQC + FVL + ++ P+ F + V + C Y + Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYR 200 Query: 1232 AYPDIWSEPSDPLELV 1247 P +WS PSD LE++ Sbjct: 201 KNPQVWSNPSDLLEIL 216 >gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 2 [Homo sapiens] Length = 590 Score = 181 bits (460), Expect = 3e-45 Identities = 145/414 (35%), Positives = 192/414 (46%), Gaps = 27/414 (6%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+ G VT C P + + L K+G A ++ PGA A F Sbjct: 27 PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83 Query: 835 LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894 I S G Y C Y + WSEPSDP+ELV T FY +PTLLA P PVV G +V L+ Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQ 143 Query: 895 CQGTFQGMRFALLQEGAHVPLQFRS----VSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950 C + F L++E +P S + A F + V + C YY Sbjct: 144 CDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNP 203 Query: 951 NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS 1010 S S L I V KP L SVV G ++TL CR V ++L+KEGE Sbjct: 204 QVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDL 263 Query: 1011 MQLWGSTSNDGA----FPITNISGTSMGRYSCC----YHPDWTSSIKIQPSNTLELLVTG 1062 +Q G G F + +S + G+Y C P W++ PS+ L++L+ G Sbjct: 264 VQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSA-----PSDPLDILIAG 318 Query: 1063 LLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEP----LEQQRPSGYRA 1117 L+P P+L QPGP VA GEN+TL CQ TF L KEGA P + + ++A Sbjct: 319 LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378 Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPST 1171 +F M V G Y C + S P+ S+ S E+ V+ PSLS ST Sbjct: 379 EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGST 432 Score = 163 bits (412), Expect = 1e-39 Identities = 124/400 (31%), Positives = 183/400 (45%), Gaps = 24/400 (6%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620 M ++ L+C GL G T + T PKP LWAE +A K +TLWC+ P T+ Sbjct: 1 MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56 Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678 E+ L K+G W R P +A F + + G Y C+ SEPS+ LELV Sbjct: 57 EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 679 GTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP----VQQLGAVGR 731 T +P + A P+ G + L+C + F L +E ++ P Q+L Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176 Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTP 791 +A F + + + C + K P WS PS+ LE+++ + KP VV Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236 Query: 792 GARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850 G +T C + + F+LYK+G ++ G S A+F + V GG Y C Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC- 295 Query: 851 YYDFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906 Y ++ WS PSDP+++++ P P L QPGP V G++V L CQ Q F L Sbjct: 296 YGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFL 355 Query: 907 LQEG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSC 942 +EG AH PL +S + A+F + V + G Y C Sbjct: 356 TKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRC 395 Score = 152 bits (385), Expect = 2e-36 Identities = 128/403 (31%), Positives = 189/403 (46%), Gaps = 32/403 (7%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926 PKPTL A+P V+ GK V L CQG + + L +EG PL+ G A Sbjct: 27 PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + + + +G Y C YYET S S PL + T + +P L A PS VV G N Sbjct: 83 FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGFYAEPTLLALPSPVVASGGN 139 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHP 1042 VTL C + ++L +E + L+ G FP+ ++ + R+ C Y+ Sbjct: 140 VTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYY 199 Query: 1043 DWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG 1102 + PS+ LE+LV G+ KPSLL G +VA G ++TLQC+ ++ FVL KEG Sbjct: 200 RKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEG 259 Query: 1103 AQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTD 1158 + ++ QQ +G +A+F + V G Y C + +P S SD L+I + Sbjct: 260 EHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAG 318 Query: 1159 KPPK-PSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAP--------QQFSEDG 1209 P P+LS P G+++TL C+ F L +G P Q + Sbjct: 319 LIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQA 378 Query: 1210 DFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F ++ V G Y C +++YP + S PS P ELV +GP Sbjct: 379 EFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSGP 420 Score = 144 bits (364), Expect = 4e-34 Identities = 109/295 (36%), Positives = 142/295 (48%), Gaps = 18/295 (6%) Query: 967 TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG--EATSMQLWGSTSNDGAFP 1024 T PKP L+AEP+SV+ G+ VTLWC+GP+ Y L KEG A Q F Sbjct: 25 TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84 Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084 I + S GRY C Y T + +PS+ LEL+ TG +P+LLA P P+VA G N+T Sbjct: 85 IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVT 141 Query: 1085 LQCQGELPDSTFVLLKEGAQEP---LEQQRPSG-YRADFWMPAVRGEDSGIYSCVYYLDS 1140 LQC TFVL++E + P Q+ P G +A F + V + C YY Sbjct: 142 LQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRK 201 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE- 1199 P SN SD LEI V KPSL ++ G +TLQCR + FVL +GE Sbjct: 202 NPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEH 261 Query: 1200 -------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV 1247 + PQ +F + V G Y C Y WS PSDPL+++ Sbjct: 262 DLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDIL 315 Score = 144 bits (363), Expect = 6e-34 Identities = 137/435 (31%), Positives = 187/435 (42%), Gaps = 32/435 (7%) Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733 LPKP + A P RG+ + L C+G L + L KEG Q P++ G +A Sbjct: 26 LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81 Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793 F I G Y C T P WSEPS+PLELV Y +P SPVV G Sbjct: 82 KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGG 138 Query: 794 RVTFNCSTPHQHMSFILYKDGSEIASSDRSWASP-GASAAHFLIISVGIGDGGNYSCRYY 852 VT C T ++F+L ++ ++ + S P G S A F + V + C YY Sbjct: 139 NVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY 198 Query: 853 ---DFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE 909 + +WS PSD +E++V KP+LL G VV G S+ L+C+ F L +E Sbjct: 199 YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKE 258 Query: 910 GAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT 965 G H +Q + A+F L V G Y C Y +S R S S PL I + Sbjct: 259 GEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLSPRWSAPSDPLDILIA 317 Query: 966 DTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA----TSMQLWGSTSND 1020 P P L +P V G+NVTL C+ + L KEG A + S + Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377 Query: 1021 GAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPG 1080 F ++ ++ G Y C + PS EL+V+G PS L+ G PG Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPS-LSPTGSTPTPG 436 Query: 1081 -ENMTLQCQGELPDS 1094 E+ L G P S Sbjct: 437 PEDQPLTPTGLDPQS 451 Score = 138 bits (347), Expect = 4e-32 Identities = 126/437 (28%), Positives = 195/437 (44%), Gaps = 24/437 (5%) Query: 12 MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68 M T +VL+ C+ +S+G + V P+P LW E A + +TLWC+ P Sbjct: 1 MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59 Query: 69 LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124 L DK + W R P + F I + +AG YRC Y GWS+PS LEL Sbjct: 60 L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEP---VDYQVPTG-T 180 A G +P G NV + C L F+L +E P ++P G + Sbjct: 117 ATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPS 176 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240 A+F + +TP + C + + P +WS PS+ L+++V G+ KP+L G ++A Sbjct: 177 QALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVAR 236 Query: 241 GESLNLRCQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297 G SL L+C+ + F L + + ++ S + ++ANF + G Y C+ Sbjct: 237 GGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCY 296 Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLA-RPSAVVQMGQNVSLRCRGPVDGVGLALY 355 ++ S R S SD L I + P L+ +P V G+NV+L C+ L Sbjct: 297 GAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLT 356 Query: 356 KKGEDKPLQFLDA--TSIDDNTSFFLNNVTYSDTGIYSCHYLL-TWKTSIRMPSHNTVEL 412 K+G P L + S F ++ VT + G Y C+ + ++ + PS+ EL Sbjct: 357 KEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSY-PQEL 415 Query: 413 MVVDKPPKPSLSAWPST 429 +V PSLS ST Sbjct: 416 VVSGPSGDPSLSPTGST 432 Score = 137 bits (344), Expect = 9e-32 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 28/405 (6%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIF 184 G LPKP W + + G V + C G L+ + L KEG +A + G A F Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I + + G Y C P WSEPS+PL+LV G Y +PTL A P P++A G ++ Sbjct: 84 HIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140 Query: 245 NLRCQGPIYGMTFALMRVED-LEKSFYHKKTIKNEANFFFQSLKIQDT--GHYLCFYYDA 301 L+C +TF L+ E L ++ Y +K K + F + + + C+YY Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYY-- 198 Query: 302 SYR-----GSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 YR S SD+L+I V K LL +VV G +++L+CR V LYK Sbjct: 199 -YRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYK 257 Query: 357 KGEDKPLQ--FLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 +GE +Q + +F L V+ S G Y C+ PS L+ Sbjct: 258 EGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIA 317 Query: 415 VDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVN 466 P P+LS P G+ +TL C+ H + F L E + +Q + Sbjct: 318 GLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQ 377 Query: 467 GDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F +S V GTY C + ++P + S S P +L+ GP+G Sbjct: 378 AEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 422 Score = 94.4 bits (233), Expect = 7e-19 Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 13/196 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G LPKP+L A+P ++A G+ +TL CQG L + L KEG ++Q P G +A F Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P+ + +G Y C Y TP S SD LE+ T +P+L A PS + G ++ Sbjct: 84 HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNV 140 Query: 1180 TLQCRGPLPGVEFVLEHDGEEAPQQF--------SEDGDFVINNVEGKGIGNYSCSYRLQ 1231 TLQC + FVL + ++ P+ F + V + C Y + Sbjct: 141 TLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYR 200 Query: 1232 AYPDIWSEPSDPLELV 1247 P +WS PSD LE++ Sbjct: 201 KNPQVWSNPSDLLEIL 216 >gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 1 [Homo sapiens] Length = 598 Score = 178 bits (451), Expect = 4e-44 Identities = 137/406 (33%), Positives = 194/406 (47%), Gaps = 25/406 (6%) Query: 867 VVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE--GAHVPLQFRSVSGNS 924 V T PKPTL A+P V+ G V L CQG+ + + L +E A + R + Sbjct: 21 VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80 Query: 925 ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMG 984 F + ++ E +G Y C YY R S LS PL++ +T +PKP L A+PS VV G Sbjct: 81 GQFHIPSITWEHTGRYGCQYYSRA---RWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137 Query: 985 QNVTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCC 1039 VTL C V G+IL KEGE Q S S+ F + +S + C Sbjct: 138 GRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCY 197 Query: 1040 YHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLL 1099 + + + PS+ LELLV G+ KPSL QPGP+VAPGE++TLQC ++ FVL Sbjct: 198 GYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLY 257 Query: 1100 KEGAQE----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIW 1155 KEG ++ P Q + +A+F + V G Y C Y + S SD L+I Sbjct: 258 KEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDIL 316 Query: 1156 VTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE-EAPQQFSE------ 1207 +T + P +S P G+++TL C+ F+L G +AP + Sbjct: 317 ITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK 376 Query: 1208 -DGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F ++ V G Y C L + P + S PS+PLELV +GP Sbjct: 377 YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELV-VSGP 421 Score = 171 bits (432), Expect = 6e-42 Identities = 131/399 (32%), Positives = 193/399 (48%), Gaps = 27/399 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 IVT L+C GL G T + T PKP LWAE + + +TL C+ S +E+ Sbjct: 4 IVTVLICLGLSLG---PRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYR 59 Query: 624 LLKD--GTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGT 680 L ++ WI TR E V+ F + ++T HTG Y C + SE S+ L LV T Sbjct: 60 LYREKKSASWI-TRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118 Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 PKP +SA P+ G + L+C+ +A GF L KEGE+E Q L + Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + ++ C + P+ WS PS+ LEL++ + KP PVV PG Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851 +T C + + F+LYK+G ++ G S A+F + V GG Y C Y Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-Y 297 Query: 852 YDFSIWSE---PSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907 ++ SE PSDP+++++T + P + QPGP V G++V L CQ Q F L Sbjct: 298 GAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLT 357 Query: 908 QEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSC 942 + G A PL+ RS+ A+F + V + +G Y C Sbjct: 358 KAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRC 396 Score = 170 bits (430), Expect = 1e-41 Identities = 139/414 (33%), Positives = 195/414 (47%), Gaps = 34/414 (8%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS----PGAS 830 PKP WA P V+T G+ VT +C + + LY++ SW + Sbjct: 27 PKPTL--WAEPDSVITQGSPVTLSCQGSLEAQEYRLYRE-----KKSASWITRIRPELVK 79 Query: 831 AAHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKS 890 F I S+ G Y C+YY + WSE SDP+ LV+T YPKPTL AQP PVV G Sbjct: 80 NGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139 Query: 891 VILRCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945 V L+C+ F L +EG + Q + + A F + V ++ C Y Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199 Query: 946 ETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKE 1005 + S S L + V KP L +P VV G+++TL C V ++L+KE Sbjct: 200 DLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKE 259 Query: 1006 GEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVT 1061 GE QL G G F + +S + G+Y CY SS PS+ L++L+T Sbjct: 260 GERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSECSAPSDPLDILIT 318 Query: 1062 G-LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE-PLE----QQRPSGY 1115 G + P + QPGP VA GEN+TL CQ TF+L K GA + PL + P Y Sbjct: 319 GQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-Y 377 Query: 1116 RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWP 1169 +A+F M V +G Y C L+S P+ S+ S+ LE+ V+ PS+ + P Sbjct: 378 QAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSP 427 Score = 162 bits (409), Expect = 3e-39 Identities = 137/442 (30%), Positives = 199/442 (45%), Gaps = 34/442 (7%) Query: 678 VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGRE 732 V T +PKP + A P +G + L C+G L + LY+E + + + + Sbjct: 21 VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 F I + + G Y C+ ++ R WSE S+PL LV+ YPKP SPVVT G Sbjct: 81 GQFHIPSITWEHTGRYGCQYYSRAR---WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137 Query: 793 ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG-IGDGGNYSCRY 851 RVT C + FIL K+G E + + P A + I SVG + +S R Sbjct: 138 GRVTLQCESQVAFGGFILCKEGEEEHPQCLN-SQPHARGSSRAIFSVGPVSPNRRWSHRC 196 Query: 852 YDFS-----IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906 Y + +WS PSD +EL+V KP+L QPGPVV PG+S+ L+C RF L Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256 Query: 907 LQEG----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962 +EG +P + + A+F L V G Y C Y +S+ S S PL I Sbjct: 257 YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDI 315 Query: 963 WVTDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGST 1017 +T P++ +P V G+NVTL C+ ++L K G A + + Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375 Query: 1018 SNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQP---G 1074 FP++ ++ G Y C + + PS LEL+V+G PS+ + P G Sbjct: 376 KYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSPPPTG 431 Query: 1075 PMVAPG--ENMTLQCQGELPDS 1094 P+ P E+ L G P S Sbjct: 432 PISTPAGPEDQPLTPTGSDPQS 453 Score = 128 bits (322), Expect = 3e-29 Identities = 117/414 (28%), Positives = 180/414 (43%), Gaps = 20/414 (4%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E + +TL C+ S + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYRLYREKK 65 Query: 76 QMTWI---RPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKP 132 +WI RP F I ++T + G Y C Y+ WS+ S L L G PKP Sbjct: 66 SASWITRIRPE-LVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKP 124 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G V + C + F+L KEG E + AIFS+ Sbjct: 125 TLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVG 184 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P + C + P +WS PS+ L+L+V G+ KP+L+ PGP++APGESL L+ Sbjct: 185 PVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQ 244 Query: 248 CQGPIYGMTFALMR--VEDLEK-SFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303 C + F L + DL + + ++ANF + G Y C+ ++ S Sbjct: 245 CVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSS 304 Query: 304 RGSLLSDVLKIWVTDTFPKT-WLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361 S SD L I +T T ++ +P V G+NV+L C+ L K G D Sbjct: 305 ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADA 364 Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 PL+ F ++ VT + G Y C+ L + +EL+V Sbjct: 365 PLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVV 418 Score = 122 bits (306), Expect = 2e-27 Identities = 112/409 (27%), Positives = 179/409 (43%), Gaps = 37/409 (9%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G +PKP W + ++ G V + C G L+ + L++E + ++ + F Sbjct: 24 GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C+ + + WSE S+PL LV+ G YPKPTL+A P P++ G + Sbjct: 84 HIPSITWEHTGRYGCQYYSR---ARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRV 140 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296 L+C+ + F L + + E H + + ++ + S I G + C Sbjct: 141 TLQCESQVAFGGFILCKEGEEE----HPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD + Y S SD+L++ V K L +P VV G++++L+C V L Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256 Query: 355 YKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVE 411 YK+GE + L+ L S F L V+ S G Y C+ + PS Sbjct: 257 YKEGE-RDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDI 315 Query: 412 LMVVDKPPKPSLSAWPSTVFKLGKAITLQC---RVSHPVL-------EFSLEWEERETFQ 461 L+ P +S P G+ +TL C R H L + L + Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375 Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPA 508 K+ +F +S V GTY C + + P + SH SEPL+L+ GP+ Sbjct: 376 KYQA--EFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPS 422 Score = 76.3 bits (186), Expect = 2e-13 Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 21/219 (9%) Query: 37 QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92 +P L ++ AP E++TL C S +F+L K D Q+ +P Q +F Sbjct: 224 KPSLSVQPGPVVAPGESLTLQCVSDVGYD-RFVLYKEGERDLRQLPGRQPQAGLSQANFT 282 Query: 93 IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149 +G ++ S G YRC + + S PS L++ GQ+ P +Q G NV Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342 Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 +LC W Q F+L K G A+ P+ ++ P A F + +T G Y C + Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLN 401 Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP---GPIMAP 240 P L S PS PL+LVV+G P++ + P GPI P Sbjct: 402 SDPYLLSHPSEPLELVVSG----PSMGSSPPPTGPISTP 436 Score = 68.6 bits (166), Expect = 4e-11 Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 12/200 (6%) Query: 317 TDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS 376 T T PK L A P +V+ G V+L C+G ++ LY++ + + N Sbjct: 23 TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82 Query: 377 FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKA 436 F + ++T+ TG Y C Y + S + + L++ PKP+LSA PS V G Sbjct: 83 FHIPSITWEHTGRYGCQYYSRARWS---ELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139 Query: 437 ITLQCRVSHPVLEFSL--EWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYR 487 +TLQC F L E EE + + S F + V ++ C Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199 Query: 488 VETHPNIWSHRSEPLKLMGP 507 P +WS S+ L+L+ P Sbjct: 200 DLNSPYVWSSPSDLLELLVP 219 Score = 39.7 bits (91), Expect = 0.020 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 12/102 (11%) Query: 602 LAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPAS----EQVRAAFPLGALTQSHTGS 657 +A +N+TL C+S F+L K G R S + +A FP+ +T +H G+ Sbjct: 335 VASGENVTLLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGT 393 Query: 658 YHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIRG 696 Y C+ + + +S PSE LELV + P + +SP G Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELV----VSGPSMGSSPPPTG 431 >gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B, member 2 isoform 2 [Homo sapiens] Length = 597 Score = 178 bits (451), Expect = 4e-44 Identities = 137/406 (33%), Positives = 194/406 (47%), Gaps = 25/406 (6%) Query: 867 VVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE--GAHVPLQFRSVSGNS 924 V T PKPTL A+P V+ G V L CQG+ + + L +E A + R + Sbjct: 21 VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80 Query: 925 ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMG 984 F + ++ E +G Y C YY R S LS PL++ +T +PKP L A+PS VV G Sbjct: 81 GQFHIPSITWEHTGRYGCQYYSRA---RWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137 Query: 985 QNVTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCC 1039 VTL C V G+IL KEGE Q S S+ F + +S + C Sbjct: 138 GRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCY 197 Query: 1040 YHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLL 1099 + + + PS+ LELLV G+ KPSL QPGP+VAPGE++TLQC ++ FVL Sbjct: 198 GYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLY 257 Query: 1100 KEGAQE----PLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIW 1155 KEG ++ P Q + +A+F + V G Y C Y + S SD L+I Sbjct: 258 KEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDIL 316 Query: 1156 VTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE-EAPQQFSE------ 1207 +T + P +S P G+++TL C+ F+L G +AP + Sbjct: 317 ITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK 376 Query: 1208 -DGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F ++ V G Y C L + P + S PS+PLELV +GP Sbjct: 377 YQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELV-VSGP 421 Score = 171 bits (432), Expect = 6e-42 Identities = 131/399 (32%), Positives = 193/399 (48%), Gaps = 27/399 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 IVT L+C GL G T + T PKP LWAE + + +TL C+ S +E+ Sbjct: 4 IVTVLICLGLSLG---PRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYR 59 Query: 624 LLKD--GTGWIATRPASEQVR-AAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGT 680 L ++ WI TR E V+ F + ++T HTG Y C + SE S+ L LV T Sbjct: 60 LYREKKSASWI-TRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118 Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 PKP +SA P+ G + L+C+ +A GF L KEGE+E Q L + Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSR 178 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + ++ C + P+ WS PS+ LEL++ + KP PVV PG Sbjct: 179 AIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPG 238 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851 +T C + + F+LYK+G ++ G S A+F + V GG Y C Y Sbjct: 239 ESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-Y 297 Query: 852 YDFSIWSE---PSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907 ++ SE PSDP+++++T + P + QPGP V G++V L CQ Q F L Sbjct: 298 GAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLT 357 Query: 908 QEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSC 942 + G A PL+ RS+ A+F + V + +G Y C Sbjct: 358 KAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRC 396 Score = 170 bits (430), Expect = 1e-41 Identities = 139/414 (33%), Positives = 195/414 (47%), Gaps = 34/414 (8%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS----PGAS 830 PKP WA P V+T G+ VT +C + + LY++ SW + Sbjct: 27 PKPTL--WAEPDSVITQGSPVTLSCQGSLEAQEYRLYRE-----KKSASWITRIRPELVK 79 Query: 831 AAHFLIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKS 890 F I S+ G Y C+YY + WSE SDP+ LV+T YPKPTL AQP PVV G Sbjct: 80 NGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139 Query: 891 VILRCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945 V L+C+ F L +EG + Q + + A F + V ++ C Y Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199 Query: 946 ETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKE 1005 + S S L + V KP L +P VV G+++TL C V ++L+KE Sbjct: 200 DLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKE 259 Query: 1006 GEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVT 1061 GE QL G G F + +S + G+Y CY SS PS+ L++L+T Sbjct: 260 GERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSECSAPSDPLDILIT 318 Query: 1062 G-LLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE-PLE----QQRPSGY 1115 G + P + QPGP VA GEN+TL CQ TF+L K GA + PL + P Y Sbjct: 319 GQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-Y 377 Query: 1116 RADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWP 1169 +A+F M V +G Y C L+S P+ S+ S+ LE+ V+ PS+ + P Sbjct: 378 QAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSP 427 Score = 164 bits (416), Expect = 4e-40 Identities = 138/441 (31%), Positives = 200/441 (45%), Gaps = 33/441 (7%) Query: 678 VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGRE 732 V T +PKP + A P +G + L C+G L + LY+E + + + + Sbjct: 21 VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 F I + + G Y C+ ++ R WSE S+PL LV+ YPKP SPVVT G Sbjct: 81 GQFHIPSITWEHTGRYGCQYYSRAR---WSELSDPLVLVMTGAYPKPTLSAQPSPVVTSG 137 Query: 793 ARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVG-IGDGGNYSCRY 851 RVT C + FIL K+G E + + P A + I SVG + +S R Sbjct: 138 GRVTLQCESQVAFGGFILCKEGEEEHPQCLN-SQPHARGSSRAIFSVGPVSPNRRWSHRC 196 Query: 852 YDFS-----IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFAL 906 Y + +WS PSD +EL+V KP+L QPGPVV PG+S+ L+C RF L Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256 Query: 907 LQEG----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMI 962 +EG +P + + A+F L V G Y C Y +S+ S S PL I Sbjct: 257 YKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSECSAPSDPLDI 315 Query: 963 WVTDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGST 1017 +T P++ +P V G+NVTL C+ ++L K G A + + Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375 Query: 1018 SNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQP---G 1074 FP++ ++ G Y C + + PS LEL+V+G PS+ + P G Sbjct: 376 KYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG----PSMGSSPPPTG 431 Query: 1075 PMVAPG-ENMTLQCQGELPDS 1094 P+ PG E+ L G P S Sbjct: 432 PISTPGPEDQPLTPTGSDPQS 452 Score = 128 bits (322), Expect = 3e-29 Identities = 117/414 (28%), Positives = 180/414 (43%), Gaps = 20/414 (4%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E + +TL C+ S + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQG-SLEAQEYRLYREKK 65 Query: 76 QMTWI---RPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKP 132 +WI RP F I ++T + G Y C Y+ WS+ S L L G PKP Sbjct: 66 SASWITRIRPE-LVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKP 124 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G V + C + F+L KEG E + AIFS+ Sbjct: 125 TLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVG 184 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P + C + P +WS PS+ L+L+V G+ KP+L+ PGP++APGESL L+ Sbjct: 185 PVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQ 244 Query: 248 CQGPIYGMTFALMR--VEDLEK-SFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303 C + F L + DL + + ++ANF + G Y C+ ++ S Sbjct: 245 CVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSS 304 Query: 304 RGSLLSDVLKIWVTDTFPKT-WLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361 S SD L I +T T ++ +P V G+NV+L C+ L K G D Sbjct: 305 ECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADA 364 Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 PL+ F ++ VT + G Y C+ L + +EL+V Sbjct: 365 PLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVV 418 Score = 122 bits (306), Expect = 2e-27 Identities = 112/409 (27%), Positives = 179/409 (43%), Gaps = 37/409 (9%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G +PKP W + ++ G V + C G L+ + L++E + ++ + F Sbjct: 24 GTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C+ + + WSE S+PL LV+ G YPKPTL+A P P++ G + Sbjct: 84 HIPSITWEHTGRYGCQYYSR---ARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRV 140 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296 L+C+ + F L + + E H + + ++ + S I G + C Sbjct: 141 TLQCESQVAFGGFILCKEGEEE----HPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRC 196 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD + Y S SD+L++ V K L +P VV G++++L+C V L Sbjct: 197 YGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVL 256 Query: 355 YKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVE 411 YK+GE + L+ L S F L V+ S G Y C+ + PS Sbjct: 257 YKEGE-RDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDI 315 Query: 412 LMVVDKPPKPSLSAWPSTVFKLGKAITLQC---RVSHPVL-------EFSLEWEERETFQ 461 L+ P +S P G+ +TL C R H L + L + Sbjct: 316 LITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYP 375 Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPA 508 K+ +F +S V GTY C + + P + SH SEPL+L+ GP+ Sbjct: 376 KYQA--EFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPS 422 Score = 78.6 bits (192), Expect = 4e-14 Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 21/220 (9%) Query: 37 QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92 +P L ++ AP E++TL C S +F+L K D Q+ +P Q +F Sbjct: 224 KPSLSVQPGPVVAPGESLTLQCVSDVGYD-RFVLYKEGERDLRQLPGRQPQAGLSQANFT 282 Query: 93 IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149 +G ++ S G YRC + + S PS L++ GQ+ P +Q G NV Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342 Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 +LC W Q F+L K G A+ P+ ++ P A F + +T G Y C + Sbjct: 343 LLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHAGTYRCYGSLN 401 Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLTAHP---GPIMAPG 241 P L S PS PL+LVV+G P++ + P GPI PG Sbjct: 402 SDPYLLSHPSEPLELVVSG----PSMGSSPPPTGPISTPG 437 Score = 68.6 bits (166), Expect = 4e-11 Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 12/200 (6%) Query: 317 TDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS 376 T T PK L A P +V+ G V+L C+G ++ LY++ + + N Sbjct: 23 TGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQ 82 Query: 377 FFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKA 436 F + ++T+ TG Y C Y + S + + L++ PKP+LSA PS V G Sbjct: 83 FHIPSITWEHTGRYGCQYYSRARWS---ELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGR 139 Query: 437 ITLQCRVSHPVLEFSL--EWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYR 487 +TLQC F L E EE + + S F + V ++ C Sbjct: 140 VTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGY 199 Query: 488 VETHPNIWSHRSEPLKLMGP 507 P +WS S+ L+L+ P Sbjct: 200 DLNSPYVWSSPSDLLELLVP 219 Score = 39.7 bits (91), Expect = 0.020 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 12/102 (11%) Query: 602 LAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPAS----EQVRAAFPLGALTQSHTGS 657 +A +N+TL C+S F+L K G R S + +A FP+ +T +H G+ Sbjct: 335 VASGENVTLLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGT 393 Query: 658 YHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIRG 696 Y C+ + + +S PSE LELV + P + +SP G Sbjct: 394 YRCYGSLNSDPYLLSHPSEPLELV----VSGPSMGSSPPPTG 431 >gi|47519953 leukocyte immunoglobulin-like receptor subfamily A member 4 [Homo sapiens] Length = 499 Score = 178 bits (451), Expect = 4e-44 Identities = 134/426 (31%), Positives = 205/426 (48%), Gaps = 30/426 (7%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKN-LTLWCRSPSGST 619 M I+T+LL GL G T + PKP LWAE P+ W N +T+WC+ Sbjct: 1 MTLILTSLLFFGLSLG---PRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTL-EA 55 Query: 620 KEFVLLKDGTGW----IATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEAL 675 + + L K+G + T + +V+ + P ++ H G YHC+ SEPS+ L Sbjct: 56 QGYRLDKEGNSMSRHILKTLESENKVKLSIP--SMMWEHAGRYHCYYQSPAGWSEPSDPL 113 Query: 676 ELVGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR- 731 ELV T +P +SA P+ G + LRC L F L +EG+ L + Sbjct: 114 ELVVT-AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHN 172 Query: 732 ----EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787 +A F + + + G + C + P+ WSEPS+PL+L++ + KP T P Sbjct: 173 HGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGP 232 Query: 788 VVTPGARVTFNCSTPHQHMSFILYKDGSE-IASSDRSWASPGASAAHFLIISVGIGDGGN 846 VVTPG +T C + ++ + LYK+G++ + G S A+F + V GG Sbjct: 233 VVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQ 292 Query: 847 YSC--RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMR 903 Y C + S WS PSDP+++++ + +P+L QPGP V G+ V L CQ Sbjct: 293 YRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFT 352 Query: 904 FALLQEG-AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959 F L +EG AH PL+ RS+ G A+F + V + +G Y C ++ S+ S P Sbjct: 353 FLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEP 412 Query: 960 LMIWVT 965 L + V+ Sbjct: 413 LELVVS 418 Score = 166 bits (419), Expect = 2e-40 Identities = 140/453 (30%), Positives = 208/453 (45%), Gaps = 41/453 (9%) Query: 863 PVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV-- 920 P V E PKP L A+PGPV+ V + CQGT + + L +EG + Sbjct: 17 PRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLE 76 Query: 921 SGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSV 980 S N + ++ E +G Y C YY++ S S PL + VT + +P L A PS V Sbjct: 77 SENKVKLSIPSMMWEHAGRYHC-YYQSPAG--WSEPSDPLELVVT-AYSRPTLSALPSPV 132 Query: 981 VPMGQNVTLWCRGPVHGVGYILHKEGE-ATSMQLWGSTSNDGAF----PITNISGTSMGR 1035 V G NVTL C + + L +EG+ S L N G F P+ ++ ++ G Sbjct: 133 VTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGT 192 Query: 1036 YSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDST 1095 + C + + T + +PS+ L+LLV+G+ KPSLL GP+V PGEN+TLQC ++ Sbjct: 193 FRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252 Query: 1096 FVLLKEGA----QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDS 1151 + L KEGA Q P Q + +A+F + V G Y C Y + S SD Sbjct: 253 YTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC-YGAHNVSSEWSAPSDP 311 Query: 1152 LEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ------- 1203 L+I + + +PSLS P G+ +TL C+ P F+L +G P Sbjct: 312 LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMY 371 Query: 1204 -QFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV--------------- 1247 +F ++ V G Y C + P + S PS+PLELV Sbjct: 372 GAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKS 431 Query: 1248 -GAAGPVAQECTVGNIVRSSLIVVVVVALGVVL 1279 P Q+ TV N++R + +V++ LG++L Sbjct: 432 DSKTAPHLQDYTVENLIRMGVAGLVLLFLGILL 464 Score = 128 bits (322), Expect = 3e-29 Identities = 119/398 (29%), Positives = 176/398 (44%), Gaps = 28/398 (7%) Query: 129 LPKPIFWIQAETPALPGCN-VNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIFS 185 LPKPI W + P + N V I C G L+ + L KEG + + + + S Sbjct: 26 LPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84 Query: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245 I ++ E G Y C P WSEPS+PL+LVV Y +PTL+A P P++ G ++ Sbjct: 85 IPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVT 140 Query: 246 LRCQGPIYGMTFALMRVEDLEKSF----YHKKTIKNEANFFFQSLKIQDTGHYLCFYYDA 301 LRC + F L+ D S+ + K +A F L + G + C+ Y+ Sbjct: 141 LRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYEN 200 Query: 302 S--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359 + Y S SD L++ V+ K LL VV G+N++L+C V + LYK+G Sbjct: 201 NTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGA 260 Query: 360 D----KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVV 415 D +P + A N F L+ V+ S G Y C+ + PS L+ Sbjct: 261 DGLPQRPGRQPQAGLSQAN--FTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAG 318 Query: 416 DKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVNG 467 +PSLS P G+ +TL C+ P+ F L E R + Sbjct: 319 QISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQA 378 Query: 468 DFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 +F +S V GTY C ++P + SH SEPL+L+ Sbjct: 379 EFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELV 416 Score = 112 bits (281), Expect = 2e-24 Identities = 113/402 (28%), Positives = 172/402 (42%), Gaps = 26/402 (6%) Query: 12 MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWEN-ITLWCRSPSRISSK 67 M T LLF +SLG + V P+P LW E P W N +T+WC+ Sbjct: 1 MTLILTSLLF-FGLSLGPRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGY 58 Query: 68 FLLLKDKTQMTWIRPSHKTFQ----VSFLIGALTESNAGLYRCCYWKETGWSKPSKVLEL 123 L DK + R KT + V I ++ +AG Y C Y GWS+PS LEL Sbjct: 59 RL---DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLEL 115 Query: 124 EAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPV----DYQVPTG 179 +P G NV + C L F L +EG +Q G Sbjct: 116 VVTAY-SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG 174 Query: 180 TM-AIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIM 238 A+F + LT + G + C + P +WSEPS+PL+L+V+G+ KP+L GP++ Sbjct: 175 KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVV 234 Query: 239 APGESLNLRCQGPIYGMTFALMR--VEDL-EKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295 PGE+L L+C + + + L + + L ++ + ++ANF + G Y Sbjct: 235 TPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294 Query: 296 CF-YYDASYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLA 353 C+ ++ S S SD L I + + L +P V G+ V+L C+ Sbjct: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354 Query: 354 LYKKGEDKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393 L K+G P L + + F ++ VT + G Y C+ Sbjct: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 396 Score = 67.8 bits (164), Expect = 7e-11 Identities = 57/185 (30%), Positives = 81/185 (43%), Gaps = 12/185 (6%) Query: 50 PWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKT----FQVSFLIGALTESNAGLYR 105 P EN+TL C S ++ L K+ RP + Q +F + ++ S G YR Sbjct: 236 PGENLTLQCGSDVGYI-RYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294 Query: 106 C--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVNILCHGWLQDLVFM 162 C + + WS PS L++ GQ+ +P +Q G V +LC W F+ Sbjct: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354 Query: 163 LFKEGYAEP-VDYQVPTGT---MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLK 218 L KEG A P + + G A F + +T G Y C P L S PS PL+ Sbjct: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLE 414 Query: 219 LVVAG 223 LVV+G Sbjct: 415 LVVSG 419 Score = 60.1 bits (144), Expect = 1e-08 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 15/198 (7%) Query: 318 DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSF 377 + PK L A P V+ V++ C+G ++ G L K+G L ++ Sbjct: 24 ENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKL 83 Query: 378 FLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAI 437 + ++ + G Y C+Y S PS + +EL VV +P+LSA PS V G + Sbjct: 84 SIPSMMWEHAGRYHCYYQSPAGWS--EPS-DPLEL-VVTAYSRPTLSALPSPVVTSGVNV 139 Query: 438 TLQCRVSHPVLEFSLEWEERETFQKFSVNGD----------FIISNVDGKGTGTYSCSYR 487 TL+C + F+L EE + +++N F + + GT+ C Sbjct: 140 TLRCASRLGLGRFTL-IEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198 Query: 488 VETHPNIWSHRSEPLKLM 505 P +WS S+PL+L+ Sbjct: 199 ENNTPYVWSEPSDPLQLL 216 >gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 [Homo sapiens] Length = 489 Score = 177 bits (450), Expect = 5e-44 Identities = 135/407 (33%), Positives = 187/407 (45%), Gaps = 26/407 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 IVT L+C L G T + T PKP LWAE + +TLWC+ T+E+ Sbjct: 4 IVTVLICLRLSLG---PRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGIL-ETQEYR 59 Query: 624 LL--KDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMA-VSEPSEALELVGT 680 L K WI P + FP+ ++T HTG Y C A SEPS+ LELV T Sbjct: 60 LYREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVT 119 Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR-----E 732 KP +SA P+ G + L C +A F L KEGE E Q L + R Sbjct: 120 GAYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSR 179 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + +Y C + P WS PS+ LEL++ + KP P+V PG Sbjct: 180 AIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPG 239 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849 +T C + + F+LYK+G + G S A+F + V GG Y C Sbjct: 240 ESLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSG 299 Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 Y S WS PSDP+++++ +F +P + PGP V G++V L CQ F L + Sbjct: 300 AYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTK 359 Query: 909 EG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSCIYYETTMSN 951 G A PL+ RS+ A+F + V + SG Y C Y + SN Sbjct: 360 AGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRC--YGSLSSN 404 Score = 169 bits (428), Expect = 2e-41 Identities = 146/458 (31%), Positives = 205/458 (44%), Gaps = 56/458 (12%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSG--NSADFLLH 930 PKPTL A+PG V+ G V L CQG + + L +E P R F + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPIP 86 Query: 931 TVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLW 990 ++ E +G Y C Y T S S PL + VT + KP L A PS VV G NVTL Sbjct: 87 SITWEHTGRYRCFYGSHTAG--WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNVTLH 144 Query: 991 CRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISGTSMGRYSCCYHPDWT 1045 C V +IL KEGE Q S F + +S + Y C + + Sbjct: 145 CVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNS 204 Query: 1046 SSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE 1105 + PS+ LELLV G+ KPSL QPGP+VAPGE++TLQC ++ FVL KEG ++ Sbjct: 205 PHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERD 264 Query: 1106 PLEQQRPSGY----RADFWMPAVRGEDSGIYSC--VYYLDSTPFAASNHSDSLEIWVTDK 1159 L+ P +A+F + V G Y C Y L S S SD L+I + + Sbjct: 265 FLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSS---EWSAPSDPLDILIAGQ 321 Query: 1160 -PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG-EEAPQQFSE-------DGD 1210 +P +S P G+++TL C+ P F+L G +AP + + Sbjct: 322 FRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAE 381 Query: 1211 FVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-------------------GAAG 1251 F ++ V G Y C L + P + S PSD LEL+ GAA Sbjct: 382 FPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAAN 441 Query: 1252 PVA----------QECTVGNIVRSSLIVVVVVALGVVL 1279 ++ Q+ TV N++R + +V+V LG++L Sbjct: 442 TLSPSQNKTASHPQDYTVENLIRMGIAGLVLVVLGILL 479 Score = 158 bits (399), Expect = 4e-38 Identities = 131/406 (32%), Positives = 188/406 (46%), Gaps = 36/406 (8%) Query: 683 LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEP--VQQLGAVGREAFFTI 737 LPKP + A P +G + L C+G L + LY+E + P + + ++ F I Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFPI 85 Query: 738 QRMEDKDEGNYSC--RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARV 795 + + G Y C +HT WSEPS+PLELV+ Y KP SPVVT G V Sbjct: 86 PSITWEHTGRYRCFYGSHTAG----WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141 Query: 796 TFNCSTPHQHMSFILYKDGSE-----IASSDRSWASPGASAAHFLIISVGIGDGGNYSCR 850 T +C + SFIL K+G + + S R + G S A F + V +Y C Sbjct: 142 TLHCVSQVAFGSFILCKEGEDEHPQCLNSQPR---THGWSRAIFSVGPVSPSRRWSYRCY 198 Query: 851 YYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALL 907 YD + +WS PSD +EL+V KP+L QPGP+V PG+S+ L+C RF L Sbjct: 199 AYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLY 258 Query: 908 QEGAHVPLQF----RSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIW 963 +EG LQ + A+F L V G Y C +S+ S S PL I Sbjct: 259 KEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRC-SGAYNLSSEWSAPSDPLDIL 317 Query: 964 VTDTF-PKPWLFAEPSSVVPMGQNVTLWCR--GPVHGVGYILHKEGEATS----MQLWGS 1016 + F +P++ P V G+NVTL C+ GP H ++L K G A + + Sbjct: 318 IAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFH--TFLLTKAGAADAPLRLRSIHEY 375 Query: 1017 TSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG 1062 FP++ ++ G Y C + PS++LEL+V+G Sbjct: 376 PKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSG 421 Score = 150 bits (378), Expect = 1e-35 Identities = 107/301 (35%), Positives = 146/301 (48%), Gaps = 28/301 (9%) Query: 967 TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS--MQLWGSTSNDGAFP 1024 T PKP L+AEP SV+ G VTLWC+G + Y L++E + ++ G FP Sbjct: 25 TLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQFP 84 Query: 1025 ITNISGTSMGRYSCCY---HPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGE 1081 I +I+ GRY C Y W+ +PS+ LEL+VTG KP+L A P P+V G Sbjct: 85 IPSITWEHTGRYRCFYGSHTAGWS-----EPSDPLELVVTGAYIKPTLSALPSPVVTSGG 139 Query: 1082 NMTLQCQGELPDSTFVLLKEGAQEPLE----QQRPSGY-RADFWMPAVRGEDSGIYSCVY 1136 N+TL C ++ +F+L KEG E + Q R G+ RA F + V Y C Sbjct: 140 NVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYA 199 Query: 1137 YLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEH 1196 Y ++P S SD LE+ V KPSLS P + G+ +TLQC + FVL Sbjct: 200 YDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYK 259 Query: 1197 DGEE--------APQQFSEDGDFVINNVEGKGIGNYSCS--YRLQAYPDIWSEPSDPLEL 1246 +GE PQ +F + V G Y CS Y L + WS PSDPL++ Sbjct: 260 EGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSE---WSAPSDPLDI 316 Query: 1247 V 1247 + Sbjct: 317 L 317 Score = 147 bits (370), Expect = 9e-35 Identities = 124/414 (29%), Positives = 189/414 (45%), Gaps = 19/414 (4%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+R+SLG + V P+P LW E +TLWC+ + ++ L ++K Sbjct: 7 VLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILE-TQEYRLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T + G YRC Y T GWS+PS LEL G KP Sbjct: 66 TAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKP 125 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEG---YAEPVDYQVPTG--TMAIFSID 187 G NV + C + F+L KEG + + ++ Q T + AIFS+ Sbjct: 126 TLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVG 185 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P +WS PS+ L+L+V G+ KP+L+ PGPI+APGESL L+ Sbjct: 186 PVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQ 245 Query: 248 CQGPIYGMTFALMRVED---LEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF-YYDASY 303 C + F L + + L+ + ++ANF + G Y C Y+ S Sbjct: 246 CVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSS 305 Query: 304 RGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-EDK 361 S SD L I + F + ++ P V G+NV+L C+ L K G D Sbjct: 306 EWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADA 365 Query: 362 PLQFLDATSIDD-NTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 PL+ F ++ VT + +G Y C+ L+ + +++ELMV Sbjct: 366 PLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMV 419 Score = 128 bits (322), Expect = 3e-29 Identities = 111/401 (27%), Positives = 172/401 (42%), Gaps = 28/401 (6%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G L+ + L++E P ++P + F Sbjct: 24 GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C WSEPS+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 PIPSITWEHTGRYRCFYGSHTAG--WSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HYLC 296 L C + +F L + + E H + + ++ S I G Y C Sbjct: 142 TLHCVSQVAFGSFILCKEGEDE----HPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRC 197 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD++ + SL SD+L++ V K L +P +V G++++L+C V L Sbjct: 198 YAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVL 257 Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 YK+GE LQ +F L V+ S G Y C + PS L Sbjct: 258 YKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDIL 317 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464 + +P +S P G+ +TL C+ P F L R + Sbjct: 318 IAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPK 377 Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 +F +S V +GTY C + ++P + SH S+ L+LM Sbjct: 378 YQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELM 418 Score = 103 bits (256), Expect = 1e-21 Identities = 91/304 (29%), Positives = 130/304 (42%), Gaps = 17/304 (5%) Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYH-KKT 274 P V AG PKPTL A PG ++ G + L CQG + + L R + + Sbjct: 17 PRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQE 76 Query: 275 IKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQ 334 I + F S+ + TG Y CFY + S SD L++ VT + K L A PS VV Sbjct: 77 IVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVT 136 Query: 335 MGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIYS 391 G NV+L C V L K+GED+ Q L++ S F + V+ S Y Sbjct: 137 SGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYR 196 Query: 392 CHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFS 451 C+ + + + +EL+V+ KPSLS P + G+++TLQC F Sbjct: 197 CYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFV 256 Query: 452 LEWEERETF--------QKFSVNGDFIISNVDGKGTGTYSCS--YRVETHPNIWSHRSEP 501 L E F Q +F + V G Y CS Y + + WS S+P Sbjct: 257 LYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSE---WSAPSDP 313 Query: 502 LKLM 505 L ++ Sbjct: 314 LDIL 317 Score = 88.6 bits (218), Expect = 4e-17 Identities = 66/197 (33%), Positives = 92/197 (46%), Gaps = 13/197 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL CQG L + L +E P + P + F Sbjct: 24 GTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKTAPWITRIPQEIVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ E +G Y C Y S S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PIPSITWEHTGRYRCFY--GSHTAGWSEPSDPLELVVTGAYIKPTLSALPSPVVTSGGNV 141 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSED--------GDFVINNVEGKGIGNYSCSYRL 1230 TL C + F+L +GE E PQ + F + V +Y C Sbjct: 142 TLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYD 201 Query: 1231 QAYPDIWSEPSDPLELV 1247 P +WS PSD LEL+ Sbjct: 202 SNSPHVWSLPSDLLELL 218 Score = 71.6 bits (174), Expect = 5e-12 Identities = 60/199 (30%), Positives = 91/199 (45%), Gaps = 14/199 (7%) Query: 37 QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92 +P L ++ AP E++TL C S +F+L K D Q+ +P Q +F Sbjct: 225 KPSLSVQPGPIVAPGESLTLQCVSDVSYD-RFVLYKEGERDFLQLPGPQPQAGLSQANFT 283 Query: 93 IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVN 149 +G ++ S G YRC Y + WS PS L++ GQ +P + G NV Sbjct: 284 LGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVT 343 Query: 150 ILCHGWLQDLVFMLFKEGYAE-PVD----YQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 +LC W F+L K G A+ P+ ++ P A F + +T G Y C + Sbjct: 344 LLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPK-YQAEFPMSPVTSAHSGTYRCYGSLS 402 Query: 205 MLPTLWSEPSNPLKLVVAG 223 P L S PS+ L+L+V+G Sbjct: 403 SNPYLLSHPSDSLELMVSG 421 Score = 47.4 bits (111), Expect = 9e-05 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 10/100 (10%) Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETF-------QKFSVNGDFII 471 PKP+L A P +V G +TL C+ E+ L + E++T Q+ G F I Sbjct: 27 PKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL-YREKKTAPWITRIPQEIVKKGQFPI 85 Query: 472 SNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYL 511 ++ + TG Y C Y +H WS S+PL+L+ Y+ Sbjct: 86 PSITWEHTGRYRCFYG--SHTAGWSEPSDPLELVVTGAYI 123 >gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 [Homo sapiens] Length = 439 Score = 177 bits (449), Expect = 6e-44 Identities = 132/410 (32%), Positives = 197/410 (48%), Gaps = 26/410 (6%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620 M I+T L+C GL L T + P PKP LWAE + +TL C+ S T+ Sbjct: 1 MTSILTVLICLGLS---LDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQ 56 Query: 621 EFVLLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHC-HSWEEMAVSEPSEALEL 677 E+ L ++ WI P + FP+ ++T H G Y C + + +SE S+ LEL Sbjct: 57 EYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLEL 116 Query: 678 VGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR--- 731 V T KP +SA P+ G + ++C +A GF L KEGE E Q L + Sbjct: 117 VVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARG 176 Query: 732 --EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVV 789 A F++ + +Y C + + P+ WS PS+ L L++ + KP PVV Sbjct: 177 SSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVV 236 Query: 790 TPGARVTFNCSTPHQHMSFILYKD-GSEIASSDRSWASPGASAAHFLIISVGIGDGGNYS 848 PG ++TF C + + F+LYK+ G + G S A+F + V GG Y+ Sbjct: 237 APGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYT 296 Query: 849 C--RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFA 905 C Y S WS PSDP+++++T + +P L +PGP V G++V L CQ F Sbjct: 297 CSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFL 356 Query: 906 LLQEG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSN 951 L +EG A PL+ +S + A+F + V + +G Y C Y + SN Sbjct: 357 LTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRC--YGSLSSN 404 Score = 168 bits (426), Expect = 3e-41 Identities = 140/417 (33%), Positives = 190/417 (45%), Gaps = 37/417 (8%) Query: 862 DPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPL 915 DP V PKPTL A+PG V+ G V LRCQG+ + + L +E +P Sbjct: 16 DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75 Query: 916 QFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFA 975 + F + ++ E +G Y CIY T+ S S PL + VT + KP L A Sbjct: 76 ELVK----KGQFPILSITWEHAGRYCCIYGSHTVGLSES--SDPLELVVTGAYSKPTLSA 129 Query: 976 EPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISG 1030 PS VV G NVT+ C V G+IL KEGE Q S S+ F + +S Sbjct: 130 LPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSP 189 Query: 1031 TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGE 1090 + Y C + + PS+ L LLV G+ KPSL QPGP+VAPGE +T QC + Sbjct: 190 SRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSD 249 Query: 1091 LPDSTFVLLKEGA----QEPLEQQRPSGYRADFWMPAVRGEDSGIYSC--VYYLDSTPFA 1144 FVL KE Q P Q + +A+F + V G Y+C Y L S Sbjct: 250 AGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSS---E 306 Query: 1145 ASNHSDSLEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----- 1198 S SD L+I +T + +P LS P G+++TL C+ F+L +G Sbjct: 307 WSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSP 366 Query: 1199 ---EEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV--GAA 1250 + Q +F ++ V G Y C L + P + + PSDPLELV GAA Sbjct: 367 LRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSGAA 423 Score = 127 bits (320), Expect = 5e-29 Identities = 119/420 (28%), Positives = 180/420 (42%), Gaps = 19/420 (4%) Query: 13 LKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFL 69 + + +L C+ +SL + V P+P LW E +TL C+ S + ++ Sbjct: 1 MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYH 59 Query: 70 LLKDKTQMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAP 126 L ++K WI P + F I ++T +AG Y C Y T G S+ S LEL Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVT 119 Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTM 181 G KP G NV I C + F+L KEG E + Sbjct: 120 GAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSR 179 Query: 182 AIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPG 241 AIFS+ ++P Y C + P +WS PS+ L L+V G+ KP+L+ PGP++APG Sbjct: 180 AIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPG 239 Query: 242 ESLNLRCQGPIYGMTFALMRV---EDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF- 297 E L +C F L + + L++ + ++ANF + G Y C Sbjct: 240 EKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSG 299 Query: 298 YYDASYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYK 356 Y+ S S SD L I +T + +L RP V G+NV+L C+ L K Sbjct: 300 AYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTK 359 Query: 357 KG-EDKPLQFLD-ATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMV 414 +G D PL+ S F ++ VT + G Y C+ L+ + + +EL+V Sbjct: 360 EGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVV 419 Score = 113 bits (283), Expect = 1e-24 Identities = 110/407 (27%), Positives = 170/407 (41%), Gaps = 40/407 (9%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G L+ + L++E ++P + F Sbjct: 24 GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQF 83 Query: 185 SIDNLTPEDEGVYIC--RTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGE 242 I ++T E G Y C +H L SE S+PL+LVV G Y KPTL+A P P++ G Sbjct: 84 PILSITWEHAGRYCCIYGSHTVGL----SESSDPLELVVTGAYSKPTLSALPSPVVTSGG 139 Query: 243 SLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTG--------HY 294 ++ ++C + F L + + E H + + + ++ S I G Y Sbjct: 140 NVTIQCDSQVAFDGFILCKEGEDE----HPQCLNSHSHARGSSRAIFSVGPVSPSRRWSY 195 Query: 295 LCFYYD--ASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGL 352 C+ YD A Y SL SD+L + V K L +P VV G+ ++ +C Sbjct: 196 RCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRF 255 Query: 353 ALYKK-GEDKPLQFLDATSID-----DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPS 406 LYK+ G D FL +F L V+ S G Y+C + PS Sbjct: 256 VLYKEWGRD----FLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPS 311 Query: 407 HNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RE 458 L+ +P LS P G+ +TL C+ + F L E + Sbjct: 312 DPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKS 371 Query: 459 TFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 Q +F +S V GTY C + ++P + +H S+PL+L+ Sbjct: 372 KRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELV 418 Score = 85.1 bits (209), Expect = 4e-16 Identities = 88/302 (29%), Positives = 133/302 (44%), Gaps = 28/302 (9%) Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTG-----WIATRPASEQVRAAF 645 KP L A + + N+T+ C S + F+L K+G + A RA F Sbjct: 124 KPTLSALPSPVVTSGGNVTIQCDSQV-AFDGFILCKEGEDEHPQCLNSHSHARGSSRAIF 182 Query: 646 PLGALTQSHTGSYHCHSWEEMAV---SEPSEALELVGTDILPKPVISASP---TIRGQEL 699 +G ++ S SY C+ ++ A S PS+ L L+ + KP +S P G++L Sbjct: 183 SVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKL 242 Query: 700 QLRCKGWLAGMGFALYKEGE----QEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTE 755 +C F LYKE Q P +Q A +A FT+ + G Y+C + Sbjct: 243 TFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTC-SGAY 301 Query: 756 KRPFKWSEPSEPLELVIK-EMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDG 814 +WS PS+PL+++I ++ +PF P V G VT C + +F+L K+G Sbjct: 302 NLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEG 361 Query: 815 SEIASSDRSWASPGAS---AAHFLIISVGIGDGGNYSCRYYDFS----IWSEPSDPVELV 867 + A S S S A F + V G Y C Y S + + PSDP+ELV Sbjct: 362 A--ADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRC-YGSLSSNPYLLTHPSDPLELV 418 Query: 868 VT 869 V+ Sbjct: 419 VS 420 Score = 70.5 bits (171), Expect = 1e-11 Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 12/208 (5%) Query: 27 LGMTSIVMDPQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRP 82 LG+ + +P L ++ AP E +T C S + +F+L K D Q +P Sbjct: 215 LGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYD-RFVLYKEWGRDFLQRPGRQP 273 Query: 83 SHKTFQVSFLIGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQL-PKPIFWIQAE 139 Q +F +G ++ S G Y C Y + WS PS L++ GQ+ +P ++ Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPG 333 Query: 140 TPALPGCNVNILCHGWLQDLVFMLFKEGYAE-PVDYQVPTGT---MAIFSIDNLTPEDEG 195 G NV +LC F+L KEG A+ P+ + + A F + +T G Sbjct: 334 PTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAG 393 Query: 196 VYICRTHIQMLPTLWSEPSNPLKLVVAG 223 Y C + P L + PS+PL+LVV+G Sbjct: 394 TYRCYGSLSSNPYLLTHPSDPLELVVSG 421 Score = 56.6 bits (135), Expect = 2e-07 Identities = 52/196 (26%), Positives = 82/196 (41%), Gaps = 11/196 (5%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380 PK L A P +V+ G V+LRC+G ++ LY++ + + F + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86 Query: 381 NVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQ 440 ++T+ G Y C Y T S + +EL+V KP+LSA PS V G +T+Q Sbjct: 87 SITWEHAGRYCCIY--GSHTVGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQ 144 Query: 441 C--RVSHPVLEFSLEWEER-------ETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETH 491 C +V+ E E+ + + S F + V +Y C Sbjct: 145 CDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRA 204 Query: 492 PNIWSHRSEPLKLMGP 507 P +WS S+ L L+ P Sbjct: 205 PYVWSLPSDLLGLLVP 220 >gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 3 [Homo sapiens] Length = 651 Score = 172 bits (436), Expect = 2e-42 Identities = 139/458 (30%), Positives = 210/458 (45%), Gaps = 27/458 (5%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ T+E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59 Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680 L ++ WI P + FP+ ++T H G Y C+ + A SE S+ LELV T Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119 Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 KP +SA P+ G + L+C +A GF+L KEGE E Q L + Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + Y C + P++WS PS+ LEL++ + KP P+V P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849 +T C + + F+LYKDG + + G S A+F + V GG Y C Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299 Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 + S WS PSDP+++++ +FY + +L QPGP V G++V L CQ F L + Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359 Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 EG A P + RS + A+F + V + +G Y C +++ ++ S PL + V Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419 Query: 965 TDTF---PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVG 999 + P +S P Q +T P G+G Sbjct: 420 SGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLG 457 Score = 159 bits (401), Expect = 2e-38 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+T G+ VT C + + LY++ R F Sbjct: 27 PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83 Query: 835 LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 I S+ G Y C Y D + SE SDP+ELVVT Y KPTL AQP PVV G +VIL Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 +C F+L +EG + Q + + A F + V Y C Y++ Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S S L + V KP L +P +V + +TL C ++L+K+GE Sbjct: 204 SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +QL G+ G F + +S + G+Y CY SS PS+ L++L+ G Sbjct: 264 DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119 + SL QPGP VA GEN+TL CQ + TF+L KEGA + + R + Y+A+F Sbjct: 323 YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164 M V +G Y C S P+ ++ SD LE+ V+ PS Sbjct: 383 PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427 Score = 155 bits (391), Expect = 3e-37 Identities = 139/451 (30%), Positives = 199/451 (44%), Gaps = 49/451 (10%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926 PKPTL A+PG V+ G V LRCQG + + L +E +P + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + ++ E +G Y C Y T S S PL + VT + KP L A+PS VV G N Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041 V L C V G+ L KEGE Q S S+ F + +S + Y C + Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200 Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101 + PS+ LELLV G+ KPSL QPGP+VAP E +TLQC + + FVL K+ Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260 Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 G ++ L+ Q + +A+F + V G Y C Y + S SD L+I + Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319 Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208 + + SLS P G+++TL C+ F+L +G Q Sbjct: 320 GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379 Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-----------------GAAG 1251 +F + V G Y C + P + + PSDPLELV +AG Sbjct: 380 AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439 Query: 1252 PVAQECT-VGNIVRSSLIVVVVVALGVVLAI 1281 P Q T G+ +S L + V +G+++A+ Sbjct: 440 PEDQPLTPTGSDPQSGLGRHLGVVIGILVAV 470 Score = 125 bits (315), Expect = 2e-28 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T +AG YRC Y +T G S+ S LEL G KP Sbjct: 66 TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G NV + C + F L KEG E + AIFS+ Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P WS PS+ L+L+V G+ KP+L+ PGPI+AP E+L L+ Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245 Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301 C F L + D E+ F + ++ANF + G Y C+ ++ Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303 Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359 S S SD L I + F + L +P V G+NV+L C+ L K+G Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363 Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418 D P + S F + VT + G Y C+ + K + + +EL+V Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423 Query: 419 PKPS 422 PS Sbjct: 424 GGPS 427 Score = 124 bits (311), Expect = 6e-28 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G + + L++E ++P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296 L+C + F+L + + E H + + ++ + S I G Y C Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD++ Y SL SD+L++ V K L +P +V + ++L+C L Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257 Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 YK GE LQ A +F L V+ S G Y C+ + PS L Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464 + + SLS P G+ +TL C+ + F L W R T+Q Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377 Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F + V GTY C + P + +H S+PL+L+ GP+G Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424 Score = 80.9 bits (198), Expect = 8e-15 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL+CQG + L +E + P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ E +G Y C Y D+ S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233 LQC + F L +GE E PQ + ++ +G S S YR AY Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201 Query: 1234 ---PDIWSEPSDPLELV 1247 P WS PSD LEL+ Sbjct: 202 SNSPYEWSLPSDLLELL 218 >gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 2 [Homo sapiens] Length = 652 Score = 172 bits (436), Expect = 2e-42 Identities = 139/458 (30%), Positives = 210/458 (45%), Gaps = 27/458 (5%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ T+E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59 Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680 L ++ WI P + FP+ ++T H G Y C+ + A SE S+ LELV T Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119 Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 KP +SA P+ G + L+C +A GF+L KEGE E Q L + Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + Y C + P++WS PS+ LEL++ + KP P+V P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849 +T C + + F+LYKDG + + G S A+F + V GG Y C Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299 Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 + S WS PSDP+++++ +FY + +L QPGP V G++V L CQ F L + Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359 Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 EG A P + RS + A+F + V + +G Y C +++ ++ S PL + V Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419 Query: 965 TDTF---PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVG 999 + P +S P Q +T P G+G Sbjct: 420 SGPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLG 457 Score = 159 bits (401), Expect = 2e-38 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+T G+ VT C + + LY++ R F Sbjct: 27 PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83 Query: 835 LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 I S+ G Y C Y D + SE SDP+ELVVT Y KPTL AQP PVV G +VIL Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 +C F+L +EG + Q + + A F + V Y C Y++ Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S S L + V KP L +P +V + +TL C ++L+K+GE Sbjct: 204 SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +QL G+ G F + +S + G+Y CY SS PS+ L++L+ G Sbjct: 264 DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119 + SL QPGP VA GEN+TL CQ + TF+L KEGA + + R + Y+A+F Sbjct: 323 YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164 M V +G Y C S P+ ++ SD LE+ V+ PS Sbjct: 383 PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427 Score = 155 bits (391), Expect = 3e-37 Identities = 139/451 (30%), Positives = 199/451 (44%), Gaps = 49/451 (10%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926 PKPTL A+PG V+ G V LRCQG + + L +E +P + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + ++ E +G Y C Y T S S PL + VT + KP L A+PS VV G N Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041 V L C V G+ L KEGE Q S S+ F + +S + Y C + Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200 Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101 + PS+ LELLV G+ KPSL QPGP+VAP E +TLQC + + FVL K+ Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260 Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 G ++ L+ Q + +A+F + V G Y C Y + S SD L+I + Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319 Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208 + + SLS P G+++TL C+ F+L +G Q Sbjct: 320 GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379 Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV-----------------GAAG 1251 +F + V G Y C + P + + PSDPLELV +AG Sbjct: 380 AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439 Query: 1252 PVAQECT-VGNIVRSSLIVVVVVALGVVLAI 1281 P Q T G+ +S L + V +G+++A+ Sbjct: 440 PEDQPLTPTGSDPQSGLGRHLGVVIGILVAV 470 Score = 125 bits (315), Expect = 2e-28 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T +AG YRC Y +T G S+ S LEL G KP Sbjct: 66 TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G NV + C + F L KEG E + AIFS+ Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P WS PS+ L+L+V G+ KP+L+ PGPI+AP E+L L+ Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245 Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301 C F L + D E+ F + ++ANF + G Y C+ ++ Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303 Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359 S S SD L I + F + L +P V G+NV+L C+ L K+G Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363 Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418 D P + S F + VT + G Y C+ + K + + +EL+V Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423 Query: 419 PKPS 422 PS Sbjct: 424 GGPS 427 Score = 124 bits (311), Expect = 6e-28 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G + + L++E ++P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296 L+C + F+L + + E H + + ++ + S I G Y C Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD++ Y SL SD+L++ V K L +P +V + ++L+C L Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257 Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 YK GE LQ A +F L V+ S G Y C+ + PS L Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464 + + SLS P G+ +TL C+ + F L W R T+Q Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377 Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F + V GTY C + P + +H S+PL+L+ GP+G Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424 Score = 80.9 bits (198), Expect = 8e-15 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL+CQG + L +E + P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ E +G Y C Y D+ S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233 LQC + F L +GE E PQ + ++ +G S S YR AY Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201 Query: 1234 ---PDIWSEPSDPLELV 1247 P WS PSD LEL+ Sbjct: 202 SNSPYEWSLPSDLLELL 218 >gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 4 [Homo sapiens] Length = 651 Score = 172 bits (435), Expect = 3e-42 Identities = 131/421 (31%), Positives = 199/421 (47%), Gaps = 24/421 (5%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ T+E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59 Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680 L ++ WI P + FP+ ++T H G Y C+ + A SE S+ LELV T Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119 Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 KP +SA P+ G + L+C +A GF+L KEGE E Q L + Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + Y C + P++WS PS+ LEL++ + KP P+V P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849 +T C + + F+LYKDG + + G S A+F + V GG Y C Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299 Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 + S WS PSDP+++++ +FY + +L QPGP V G++V L CQ F L + Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359 Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 EG A P + RS + A+F + V + +G Y C +++ ++ S PL + V Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419 Query: 965 T 965 + Sbjct: 420 S 420 Score = 159 bits (401), Expect = 2e-38 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+T G+ VT C + + LY++ R F Sbjct: 27 PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83 Query: 835 LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 I S+ G Y C Y D + SE SDP+ELVVT Y KPTL AQP PVV G +VIL Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 +C F+L +EG + Q + + A F + V Y C Y++ Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S S L + V KP L +P +V + +TL C ++L+K+GE Sbjct: 204 SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +QL G+ G F + +S + G+Y CY SS PS+ L++L+ G Sbjct: 264 DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119 + SL QPGP VA GEN+TL CQ + TF+L KEGA + + R + Y+A+F Sbjct: 323 YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164 M V +G Y C S P+ ++ SD LE+ V+ PS Sbjct: 383 PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427 Score = 154 bits (390), Expect = 4e-37 Identities = 130/404 (32%), Positives = 182/404 (45%), Gaps = 32/404 (7%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926 PKPTL A+PG V+ G V LRCQG + + L +E +P + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + ++ E +G Y C Y T S S PL + VT + KP L A+PS VV G N Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041 V L C V G+ L KEGE Q S S+ F + +S + Y C + Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200 Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101 + PS+ LELLV G+ KPSL QPGP+VAP E +TLQC + + FVL K+ Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260 Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 G ++ L+ Q + +A+F + V G Y C Y + S SD L+I + Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319 Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208 + + SLS P G+++TL C+ F+L +G Q Sbjct: 320 GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379 Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F + V G Y C + P + + PSDPLELV +GP Sbjct: 380 AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELV-VSGP 422 Score = 135 bits (339), Expect = 3e-31 Identities = 131/436 (30%), Positives = 183/436 (41%), Gaps = 32/436 (7%) Query: 683 LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734 LPKP + A P +G + LRC+G + LY+E + Q+L G+ Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ--- 82 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F I + + G Y C ++ SE S+PLELV+ Y KP SPVV G Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN---YSCRY 851 V C + F L K+G + + + P A + I SVG Y C Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLN-SQPHARGSSRAIFSVGPVSPSRRWWYRCYA 199 Query: 852 YDFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 YD + WS PSD +EL+V KP+L QPGP+V P +++ L+C RF L + Sbjct: 200 YDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYK 259 Query: 909 EGAHVPLQFRSVSGNS----ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 +G LQ + A+F L V G Y C Y +S+ S S PL I + Sbjct: 260 DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILI 318 Query: 965 TDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGSTSN 1019 F + L +P V G+NVTL C+ ++L KEG A + S Sbjct: 319 AGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKY 378 Query: 1020 DGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAP 1079 FP+ ++ G Y C + PS+ LEL+V+G PS GP Sbjct: 379 QAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTS 437 Query: 1080 G-ENMTLQCQGELPDS 1094 G E+ L G P S Sbjct: 438 GPEDQPLTPTGSDPQS 453 Score = 125 bits (315), Expect = 2e-28 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T +AG YRC Y +T G S+ S LEL G KP Sbjct: 66 TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G NV + C + F L KEG E + AIFS+ Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P WS PS+ L+L+V G+ KP+L+ PGPI+AP E+L L+ Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245 Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301 C F L + D E+ F + ++ANF + G Y C+ ++ Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303 Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359 S S SD L I + F + L +P V G+NV+L C+ L K+G Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363 Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418 D P + S F + VT + G Y C+ + K + + +EL+V Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423 Query: 419 PKPS 422 PS Sbjct: 424 GGPS 427 Score = 124 bits (311), Expect = 6e-28 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G + + L++E ++P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296 L+C + F+L + + E H + + ++ + S I G Y C Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD++ Y SL SD+L++ V K L +P +V + ++L+C L Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257 Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 YK GE LQ A +F L V+ S G Y C+ + PS L Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464 + + SLS P G+ +TL C+ + F L W R T+Q Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377 Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F + V GTY C + P + +H S+PL+L+ GP+G Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424 Score = 80.9 bits (198), Expect = 8e-15 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL+CQG + L +E + P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ E +G Y C Y D+ S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233 LQC + F L +GE E PQ + ++ +G S S YR AY Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201 Query: 1234 ---PDIWSEPSDPLELV 1247 P WS PSD LEL+ Sbjct: 202 SNSPYEWSLPSDLLELL 218 >gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B, member 1 isoform 1 [Homo sapiens] Length = 650 Score = 172 bits (435), Expect = 3e-42 Identities = 131/421 (31%), Positives = 199/421 (47%), Gaps = 24/421 (5%) Query: 565 IVTALLCCGLCNGVLIEETEIVMP-TPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL G T + PKP LWAE + +TL C+ T+E+ Sbjct: 4 ILTVLICLGLSLG---PRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYR 59 Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAV-SEPSEALELVGT 680 L ++ WI P + FP+ ++T H G Y C+ + A SE S+ LELV T Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVT 119 Query: 681 DILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAV-----GRE 732 KP +SA P+ G + L+C +A GF+L KEGE E Q L + Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSR 179 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + Y C + P++WS PS+ LEL++ + KP P+V P Sbjct: 180 AIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPE 239 Query: 793 ARVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSC-- 849 +T C + + F+LYKDG + + G S A+F + V GG Y C Sbjct: 240 ETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYG 299 Query: 850 RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 + S WS PSDP+++++ +FY + +L QPGP V G++V L CQ F L + Sbjct: 300 AHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTK 359 Query: 909 EG-AHVPLQFRSVSGN---SADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 EG A P + RS + A+F + V + +G Y C +++ ++ S PL + V Sbjct: 360 EGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVV 419 Query: 965 T 965 + Sbjct: 420 S 420 Score = 159 bits (401), Expect = 2e-38 Identities = 133/405 (32%), Positives = 186/405 (45%), Gaps = 21/405 (5%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+T G+ VT C + + LY++ R F Sbjct: 27 PKPTL--WAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRI-PQELVKKGQF 83 Query: 835 LIISVGIGDGGNYSCRY-YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 I S+ G Y C Y D + SE SDP+ELVVT Y KPTL AQP PVV G +VIL Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVIL 143 Query: 894 RCQGTFQGMRFALLQEGAH-----VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 +C F+L +EG + Q + + A F + V Y C Y++ Sbjct: 144 QCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSN 203 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 S S L + V KP L +P +V + +TL C ++L+K+GE Sbjct: 204 SPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGER 263 Query: 1009 TSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG-L 1063 +QL G+ G F + +S + G+Y CY SS PS+ L++L+ G Sbjct: 264 DFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR-CYGAHNLSSEWSAPSDPLDILIAGQF 322 Query: 1064 LPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPS----GYRADF 1119 + SL QPGP VA GEN+TL CQ + TF+L KEGA + + R + Y+A+F Sbjct: 323 YDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQAEF 382 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPS 1164 M V +G Y C S P+ ++ SD LE+ V+ PS Sbjct: 383 PMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS 427 Score = 154 bits (390), Expect = 4e-37 Identities = 130/404 (32%), Positives = 182/404 (45%), Gaps = 32/404 (7%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPLQFRSVSGNSAD 926 PKPTL A+PG V+ G V LRCQG + + L +E +P + Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVK----KGQ 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + ++ E +G Y C Y T S S PL + VT + KP L A+PS VV G N Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGRSES--SDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGST-----SNDGAFPITNISGTSMGRYSCCYH 1041 V L C V G+ L KEGE Q S S+ F + +S + Y C + Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAY 200 Query: 1042 PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKE 1101 + PS+ LELLV G+ KPSL QPGP+VAP E +TLQC + + FVL K+ Sbjct: 201 DSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKD 260 Query: 1102 GAQEPLE----QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVT 1157 G ++ L+ Q + +A+F + V G Y C Y + S SD L+I + Sbjct: 261 GERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILIA 319 Query: 1158 DK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG--------EEAPQQFSED 1208 + + SLS P G+++TL C+ F+L +G Q Sbjct: 320 GQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKYQ 379 Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGP 1252 +F + V G Y C + P + + PSDPLELV +GP Sbjct: 380 AEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELV-VSGP 422 Score = 135 bits (339), Expect = 3e-31 Identities = 131/436 (30%), Positives = 183/436 (41%), Gaps = 32/436 (7%) Query: 683 LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734 LPKP + A P +G + LRC+G + LY+E + Q+L G+ Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQ--- 82 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F I + + G Y C ++ SE S+PLELV+ Y KP SPVV G Sbjct: 83 FPIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGN 140 Query: 795 VTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN---YSCRY 851 V C + F L K+G + + + P A + I SVG Y C Sbjct: 141 VILQCDSQVAFDGFSLCKEGEDEHPQCLN-SQPHARGSSRAIFSVGPVSPSRRWWYRCYA 199 Query: 852 YDFSI---WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 YD + WS PSD +EL+V KP+L QPGP+V P +++ L+C RF L + Sbjct: 200 YDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYK 259 Query: 909 EGAHVPLQFRSVSGNS----ADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 +G LQ + A+F L V G Y C Y +S+ S S PL I + Sbjct: 260 DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRC-YGAHNLSSEWSAPSDPLDILI 318 Query: 965 TDTF-PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATS----MQLWGSTSN 1019 F + L +P V G+NVTL C+ ++L KEG A + S Sbjct: 319 AGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQKY 378 Query: 1020 DGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAP 1079 FP+ ++ G Y C + PS+ LEL+V+G PS GP Sbjct: 379 QAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTS 437 Query: 1080 G-ENMTLQCQGELPDS 1094 G E+ L G P S Sbjct: 438 GPEDQPLTPTGSDPQS 453 Score = 125 bits (315), Expect = 2e-28 Identities = 122/424 (28%), Positives = 181/424 (42%), Gaps = 23/424 (5%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SLG + V P+P LW E +TL C+ + ++ L ++K Sbjct: 7 VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQE-TQEYRLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T +AG YRC Y +T G S+ S LEL G KP Sbjct: 66 TALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKP 125 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 Q G NV + C + F L KEG E + AIFS+ Sbjct: 126 TLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVG 185 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P WS PS+ L+L+V G+ KP+L+ PGPI+AP E+L L+ Sbjct: 186 PVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQ 245 Query: 248 CQGPIYGMTFALMRVEDLEKSFYHKKTIK-----NEANFFFQSLKIQDTGHYLCF-YYDA 301 C F L + D E+ F + ++ANF + G Y C+ ++ Sbjct: 246 CGSDAGYNRFVLYK--DGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNL 303 Query: 302 SYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG-E 359 S S SD L I + F + L +P V G+NV+L C+ L K+G Sbjct: 304 SSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAA 363 Query: 360 DKPLQFLDA-TSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKP 418 D P + S F + VT + G Y C+ + K + + +EL+V Sbjct: 364 DDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPS 423 Query: 419 PKPS 422 PS Sbjct: 424 GGPS 427 Score = 124 bits (311), Expect = 6e-28 Identities = 111/407 (27%), Positives = 172/407 (42%), Gaps = 30/407 (7%) Query: 127 GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIF 184 G LPKP W + + G V + C G + + L++E ++P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 185 SIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESL 244 I ++T E G Y C SE S+PL+LVV G Y KPTL+A P P++ G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTAGR--SESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 245 NLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGH--------YLC 296 L+C + F+L + + E H + + ++ + S I G Y C Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDE----HPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRC 197 Query: 297 FYYDAS--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLAL 354 + YD++ Y SL SD+L++ V K L +P +V + ++L+C L Sbjct: 198 YAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVL 257 Query: 355 YKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVEL 412 YK GE LQ A +F L V+ S G Y C+ + PS L Sbjct: 258 YKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDIL 317 Query: 413 MVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLE--------WEERETFQKFS 464 + + SLS P G+ +TL C+ + F L W R T+Q Sbjct: 318 IAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQSQK 377 Query: 465 VNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM--GPAG 509 +F + V GTY C + P + +H S+PL+L+ GP+G Sbjct: 378 YQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG 424 Score = 80.9 bits (198), Expect = 8e-15 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 13/197 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL+CQG + L +E + P + F Sbjct: 24 GHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P++ E +G Y C Y D+ S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PIPSITWEHAGRYRCYYGSDTA--GRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNV 141 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQQFSEDGDFVINNVEGKGIGNYSCS----YRLQAY- 1233 LQC + F L +GE E PQ + ++ +G S S YR AY Sbjct: 142 ILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYD 201 Query: 1234 ---PDIWSEPSDPLELV 1247 P WS PSD LEL+ Sbjct: 202 SNSPYEWSLPSDLLELL 218 >gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens] Length = 286 Score = 146 bits (369), Expect = 1e-34 Identities = 88/234 (37%), Positives = 122/234 (52%), Gaps = 14/234 (5%) Query: 957 SMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGS 1016 S+ +++ PKPWL A+P++VV G NVTL CR P + L K GE + Sbjct: 23 SVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV 82 Query: 1017 TSNDGAFPITNISGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGP 1075 +S F + ++ G Y CCY PDW + QPS+ LELLVT LP+PSL+A PGP Sbjct: 83 SSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGP 142 Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCV 1135 +V PG N++L+C G L + +FVL +EG PL+ + + ADF + R G YSC Sbjct: 143 VVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCY 200 Query: 1136 YYLDSTPFAASNHSDSLEI-WVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLP 1188 Y+ S P+ S S+ L I W + P S+ P +Q GP P Sbjct: 201 YHTPSAPYVLSQRSEVLVISWEGEGPEARPASSAPG----------MQAPGPPP 244 Score = 124 bits (310), Expect = 8e-28 Identities = 75/186 (40%), Positives = 99/186 (53%), Gaps = 9/186 (4%) Query: 764 PSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRS 823 PS + + +PKP+ + VVTPG VT C P F L+K G EIA Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--L 78 Query: 824 WASPGASAAHFLIISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLA 879 + + A F + V GG Y C Y + +WS+PSD +EL+VTE P+P+L+A Sbjct: 79 FRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVA 138 Query: 880 QPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGN 939 PGPVV PG +V LRC G + M F L +EG PLQ+R + ADF L +GA G Sbjct: 139 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGT 196 Query: 940 YSCIYY 945 YSC Y+ Sbjct: 197 YSCYYH 202 Score = 105 bits (263), Expect = 2e-22 Identities = 71/200 (35%), Positives = 100/200 (50%), Gaps = 7/200 (3%) Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109 I PS + + PKP L AQP +V PG N+TL+C+ P F L K G PL Sbjct: 20 ITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79 Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAW 1168 + S A+F++ V GIY C Y D P S SD LE+ VT++ P+PSL A Sbjct: 80 RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVAL 139 Query: 1169 PSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNY 1224 P + G +++L+C G L + FVL +G AP Q+ DF + + + G Y Sbjct: 140 PGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTY 197 Query: 1225 SCSYRLQAYPDIWSEPSDPL 1244 SC Y + P + S+ S+ L Sbjct: 198 SCYYHTPSAPYVLSQRSEVL 217 Score = 98.2 bits (243), Expect = 5e-20 Identities = 65/201 (32%), Positives = 101/201 (50%), Gaps = 6/201 (2%) Query: 117 PSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQV 176 PS + + PKP Q T PG NV + C F LFK G P+ ++ Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81 Query: 177 PTGTMAIFSIDNLTPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPG 235 + +A F ++ +TP G+Y C P +WS+PS+ L+L+V P+P+L A PG Sbjct: 82 VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141 Query: 236 PIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295 P++ PG +++LRC G + M+F L R E + ++ + + A+F L + G Y Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYS 198 Query: 296 CFYY--DASYRGSLLSDVLKI 314 C+Y+ A Y S S+VL I Sbjct: 199 CYYHTPSAPYVLSQRSEVLVI 219 Score = 97.8 bits (242), Expect = 6e-20 Identities = 68/190 (35%), Positives = 94/190 (49%), Gaps = 15/190 (7%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380 PK WL A+P+ VV G NV+LRCR P L+K GE PL F D +S + FFL Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 92 Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 VT + GIY C Y W + + +EL+V ++ P+PSL A P V G ++L Sbjct: 93 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 152 Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492 +C + F L E R + Q ++ DF + + + GTYSC Y + P Sbjct: 153 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 207 Query: 493 NIWSHRSEPL 502 + S RSE L Sbjct: 208 YVLSQRSEVL 217 Score = 90.5 bits (223), Expect = 1e-17 Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 16/221 (7%) Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPT----PKPELWAETNFPLAPWKNLTLWCRSP 615 + ++ I+ L LC+ + I++P PKP L A+ + P N+TL CR+P Sbjct: 1 MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60 Query: 616 SGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSE 670 + + F L K G + R S ++ A F L +T + G Y C W S+ Sbjct: 61 QPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQ 118 Query: 671 PSEALELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727 PS+ LEL+ T+ LP+P + A P G + LRC G L M F LY+EG P+Q Sbjct: 119 PSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRH 178 Query: 728 AVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768 + A FT+ + + G YSC HT P+ S+ SE L Sbjct: 179 SAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 217 Score = 90.5 bits (223), Expect = 1e-17 Identities = 63/210 (30%), Positives = 96/210 (45%), Gaps = 7/210 (3%) Query: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 P+P L + P N+TL CR+P + +F L K + + F + Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 93 Query: 96 LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151 +T + G+YRCCY W WS+PS VLEL +LP+P PG NV++ Sbjct: 94 VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 153 Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211 C G L+++ F+L++EG A P+ Y+ A F++ L G Y C H P + S Sbjct: 154 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 211 Query: 212 EPSNPLKLVVAGLYPKPTLTAHPGPIMAPG 241 + S L + G P+ + + APG Sbjct: 212 QRSEVLVISWEGEGPEARPASSAPGMQAPG 241 Score = 86.7 bits (213), Expect = 1e-16 Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 16/202 (7%) Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256 I L TLW PS + + A +PKP L A P ++ PG ++ LRC+ P Sbjct: 6 ILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 65 Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312 F L + ++ + + + +E A FF + + G Y C Y + + S DVL Sbjct: 66 FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 123 Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372 ++ VT+ P+ L+A P VV G NVSLRC G + + LY++G PLQ+ S Sbjct: 124 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 181 Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394 F L + G YSC+Y Sbjct: 182 PWADFTL--LGARAPGTYSCYY 201 Score = 84.7 bits (208), Expect = 5e-16 Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 9/186 (4%) Query: 671 PSEALELVGTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727 PS A+ + PKP + A P G + LRC+ F L+K GE P+ Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81 Query: 728 AVGREAFFTIQRMEDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWAS 786 A F ++ + G Y C + P WS+PS+ LEL++ E P+P Sbjct: 82 VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141 Query: 787 PVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN 846 PVV PGA V+ C+ ++MSF+LY++G R A P A +G G Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGT 196 Query: 847 YSCRYY 852 YSC Y+ Sbjct: 197 YSCYYH 202 Score = 65.1 bits (157), Expect = 4e-10 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Query: 1161 PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQF----SEDGDFVINNV 1216 PKP L A P+T+ G ++TL+CR P P F L GE AP F SE +F + V Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 94 Query: 1217 EGKGIGNYSCSYRLQAY-PDIWSEPSDPLELV 1247 G Y C YR + P +WS+PSD LEL+ Sbjct: 95 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELL 126 Score = 45.8 bits (107), Expect = 3e-04 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 7/93 (7%) Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERE----TFQKFSVN-GDFIISN 473 PKP L A P+TV G +TL+CR P F L ++ E F+ S +F + Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGL-FKPGEIAPLLFRDVSSELAEFFLEE 93 Query: 474 VDGKGTGTYSCSY-RVETHPNIWSHRSEPLKLM 505 V G Y C Y R + P +WS S+ L+L+ Sbjct: 94 VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELL 126 >gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens] Length = 267 Score = 144 bits (363), Expect = 6e-34 Identities = 80/199 (40%), Positives = 111/199 (55%), Gaps = 3/199 (1%) Query: 957 SMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGS 1016 S+ +++ PKPWL A+P++VV G NVTL CR P + L K GE + Sbjct: 23 SVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV 82 Query: 1017 TSNDGAFPITNISGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGP 1075 +S F + ++ G Y CCY PDW + QPS+ LELLVT LP+PSL+A PGP Sbjct: 83 SSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGP 142 Query: 1076 MVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCV 1135 +V PG N++L+C G L + +FVL +EG PL+ + + ADF + R G YSC Sbjct: 143 VVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCY 200 Query: 1136 YYLDSTPFAASNHSDSLEI 1154 Y+ S P+ S S+ L I Sbjct: 201 YHTPSAPYVLSQRSEVLVI 219 Score = 124 bits (310), Expect = 8e-28 Identities = 75/186 (40%), Positives = 99/186 (53%), Gaps = 9/186 (4%) Query: 764 PSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRS 823 PS + + +PKP+ + VVTPG VT C P F L+K G EIA Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--L 78 Query: 824 WASPGASAAHFLIISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLA 879 + + A F + V GG Y C Y + +WS+PSD +EL+VTE P+P+L+A Sbjct: 79 FRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVA 138 Query: 880 QPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGN 939 PGPVV PG +V LRC G + M F L +EG PLQ+R + ADF L +GA G Sbjct: 139 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGT 196 Query: 940 YSCIYY 945 YSC Y+ Sbjct: 197 YSCYYH 202 Score = 123 bits (308), Expect = 1e-27 Identities = 82/244 (33%), Positives = 124/244 (50%), Gaps = 8/244 (3%) Query: 1050 IQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQ 1109 I PS + + PKP L AQP +V PG N+TL+C+ P F L K G PL Sbjct: 20 ITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF 79 Query: 1110 QRPSGYRADFWMPAVRGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAW 1168 + S A+F++ V GIY C Y D P S SD LE+ VT++ P+PSL A Sbjct: 80 RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVAL 139 Query: 1169 PSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNY 1224 P + G +++L+C G L + FVL +G AP Q+ DF + + + G Y Sbjct: 140 PGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTY 197 Query: 1225 SCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWK 1284 SC Y + P + S+ S+ L ++ + + T GN+VR L +V+++LG ++ +W+ Sbjct: 198 SCYYHTPSAPYVLSQRSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWR 256 Query: 1285 KWPR 1288 R Sbjct: 257 SQNR 260 Score = 99.0 bits (245), Expect = 3e-20 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380 PK WL A+P+ VV G NV+LRCR P L+K GE PL F D +S + FFL Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 92 Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 VT + GIY C Y W + + +EL+V ++ P+PSL A P V G ++L Sbjct: 93 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 152 Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492 +C + F L E R + Q ++ DF + + + GTYSC Y + P Sbjct: 153 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 207 Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542 + S RSE L + + +Y +RL L ++ L ++ W+ Sbjct: 208 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 256 Score = 98.2 bits (243), Expect = 5e-20 Identities = 65/201 (32%), Positives = 101/201 (50%), Gaps = 6/201 (2%) Query: 117 PSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQV 176 PS + + PKP Q T PG NV + C F LFK G P+ ++ Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81 Query: 177 PTGTMAIFSIDNLTPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPG 235 + +A F ++ +TP G+Y C P +WS+PS+ L+L+V P+P+L A PG Sbjct: 82 VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141 Query: 236 PIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295 P++ PG +++LRC G + M+F L R E + ++ + + A+F L + G Y Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYS 198 Query: 296 CFYY--DASYRGSLLSDVLKI 314 C+Y+ A Y S S+VL I Sbjct: 199 CYYHTPSAPYVLSQRSEVLVI 219 Score = 90.5 bits (223), Expect = 1e-17 Identities = 72/221 (32%), Positives = 106/221 (47%), Gaps = 16/221 (7%) Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPT----PKPELWAETNFPLAPWKNLTLWCRSP 615 + ++ I+ L LC+ + I++P PKP L A+ + P N+TL CR+P Sbjct: 1 MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60 Query: 616 SGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSE 670 + + F L K G + R S ++ A F L +T + G Y C W S+ Sbjct: 61 QPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQ 118 Query: 671 PSEALELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727 PS+ LEL+ T+ LP+P + A P G + LRC G L M F LY+EG P+Q Sbjct: 119 PSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRH 178 Query: 728 AVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768 + A FT+ + + G YSC HT P+ S+ SE L Sbjct: 179 SAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 217 Score = 86.7 bits (213), Expect = 1e-16 Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 16/202 (7%) Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256 I L TLW PS + + A +PKP L A P ++ PG ++ LRC+ P Sbjct: 6 ILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 65 Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312 F L + ++ + + + +E A FF + + G Y C Y + + S DVL Sbjct: 66 FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 123 Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372 ++ VT+ P+ L+A P VV G NVSLRC G + + LY++G PLQ+ S Sbjct: 124 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 181 Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394 F L + G YSC+Y Sbjct: 182 PWADFTL--LGARAPGTYSCYY 201 Score = 86.7 bits (213), Expect = 1e-16 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%) Query: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 P+P L + P N+TL CR+P + +F L K + + F + Sbjct: 35 PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 93 Query: 96 LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151 +T + G+YRCCY W WS+PS VLEL +LP+P PG NV++ Sbjct: 94 VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 153 Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211 C G L+++ F+L++EG A P+ Y+ A F++ L G Y C H P + S Sbjct: 154 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 211 Query: 212 EPSNPL 217 + S L Sbjct: 212 QRSEVL 217 Score = 84.7 bits (208), Expect = 5e-16 Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 9/186 (4%) Query: 671 PSEALELVGTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG 727 PS A+ + PKP + A P G + LRC+ F L+K GE P+ Sbjct: 22 PSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRD 81 Query: 728 AVGREAFFTIQRMEDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWAS 786 A F ++ + G Y C + P WS+PS+ LEL++ E P+P Sbjct: 82 VSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPG 141 Query: 787 PVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGN 846 PVV PGA V+ C+ ++MSF+LY++G R A P A +G G Sbjct: 142 PVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGT 196 Query: 847 YSCRYY 852 YSC Y+ Sbjct: 197 YSCYYH 202 >gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens] Length = 263 Score = 144 bits (362), Expect = 7e-34 Identities = 79/187 (42%), Positives = 106/187 (56%), Gaps = 3/187 (1%) Query: 969 PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028 PKPWL A+P++VV G NVTL CR P + L K GE + +S F + + Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90 Query: 1029 SGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087 + G Y CCY PDW + QPS+ LELLVT LP+PSL+A PGP+V PG N++L+C Sbjct: 91 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150 Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147 G L + +FVL +EG PL+ + + ADF + R G YSC Y+ S P+ S Sbjct: 151 AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPSAPYVLSQ 208 Query: 1148 HSDSLEI 1154 S+ L I Sbjct: 209 RSEVLVI 215 Score = 123 bits (309), Expect = 1e-27 Identities = 73/174 (41%), Positives = 95/174 (54%), Gaps = 9/174 (5%) Query: 776 YPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFL 835 +PKP+ + VVTPG VT C P F L+K G EIA + + A F Sbjct: 30 HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--LFRDVSSELAEFF 86 Query: 836 IISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891 + V GG Y C Y + +WS+PSD +EL+VTE P+P+L+A PGPVV PG +V Sbjct: 87 LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 146 Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945 LRC G + M F L +EG PLQ+R + ADF L +GA G YSC Y+ Sbjct: 147 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 198 Score = 122 bits (306), Expect = 2e-27 Identities = 79/229 (34%), Positives = 119/229 (51%), Gaps = 8/229 (3%) Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAV 1124 PKP L AQP +V PG N+TL+C+ P F L K G PL + S A+F++ V Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90 Query: 1125 RGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183 GIY C Y D P S SD LE+ VT++ P+PSL A P + G +++L+C Sbjct: 91 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150 Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239 G L + FVL +G AP Q+ DF + + + G YSC Y + P + S+ Sbjct: 151 AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQ 208 Query: 1240 PSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWKKWPR 1288 S+ L ++ + + T GN+VR L +V+++LG ++ +W+ R Sbjct: 209 RSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 256 Score = 103 bits (258), Expect = 8e-22 Identities = 68/187 (36%), Positives = 88/187 (47%), Gaps = 3/187 (1%) Query: 871 FYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLH 930 ++PKP L AQP VV PG +V LRC+ RF L + G PL FR VS A+F L Sbjct: 29 YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 88 Query: 931 TVGAEDSGNYSCIYYETTMS-NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 V G Y C Y S S L + VT+ P+P L A P VV G NV+L Sbjct: 89 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 148 Query: 990 WCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIK 1049 C G + + ++L++EG A +Q S F T + + G YSC YH + Sbjct: 149 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADF--TLLGARAPGTYSCYYHTPSAPYVL 206 Query: 1050 IQPSNTL 1056 Q S L Sbjct: 207 SQRSEVL 213 Score = 99.0 bits (245), Expect = 3e-20 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380 PK WL A+P+ VV G NV+LRCR P L+K GE PL F D +S + FFL Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 88 Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 VT + GIY C Y W + + +EL+V ++ P+PSL A P V G ++L Sbjct: 89 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 148 Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492 +C + F L E R + Q ++ DF + + + GTYSC Y + P Sbjct: 149 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 203 Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542 + S RSE L + + +Y +RL L ++ L ++ W+ Sbjct: 204 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 252 Score = 97.4 bits (241), Expect = 8e-20 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 6/188 (3%) Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNL 189 PKP Q T PG NV + C F LFK G P+ ++ + +A F ++ + Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90 Query: 190 TPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248 TP G+Y C P +WS+PS+ L+L+V P+P+L A PGP++ PG +++LRC Sbjct: 91 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150 Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYY--DASYRGS 306 G + M+F L R E + ++ + + A+F L + G Y C+Y+ A Y S Sbjct: 151 AGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 207 Query: 307 LLSDVLKI 314 S+VL I Sbjct: 208 QRSEVLVI 215 Score = 87.4 bits (215), Expect = 8e-17 Identities = 70/217 (32%), Positives = 102/217 (47%), Gaps = 12/217 (5%) Query: 560 VTMLFIVTALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGST 619 + ++ I+ L LC+ + PKP L A+ + P N+TL CR+P + Sbjct: 1 MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 60 Query: 620 KEFVLLKDGT-GWIATRPASEQVRAAFPLGALTQSHTGSYHC----HSWEEMAVSEPSEA 674 + F L K G + R S ++ A F L +T + G Y C W S+PS+ Sbjct: 61 R-FGLFKPGEIAPLLFRDVSSEL-AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDV 118 Query: 675 LELVGTDILPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR 731 LEL+ T+ LP+P + A P G + LRC G L M F LY+EG P+Q + Sbjct: 119 LELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP 178 Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPL 768 A FT+ + + G YSC HT P+ S+ SE L Sbjct: 179 WADFTL--LGARAPGTYSCYYHTPSAPYVLSQRSEVL 213 Score = 86.7 bits (213), Expect = 1e-16 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%) Query: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 P+P L + P N+TL CR+P + +F L K + + F + Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 89 Query: 96 LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151 +T + G+YRCCY W WS+PS VLEL +LP+P PG NV++ Sbjct: 90 VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 149 Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211 C G L+++ F+L++EG A P+ Y+ A F++ L G Y C H P + S Sbjct: 150 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 207 Query: 212 EPSNPL 217 + S L Sbjct: 208 QRSEVL 213 Score = 84.7 bits (208), Expect = 5e-16 Identities = 65/202 (32%), Positives = 94/202 (46%), Gaps = 20/202 (9%) Query: 203 IQMLPTLWS------EPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMT 256 I L TLW PS P A +PKP L A P ++ PG ++ LRC+ P Sbjct: 6 ILQLLTLWPLCHTDITPSVP----PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWR 61 Query: 257 FALMRVEDLEKSFYHKKTIKNE-ANFFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVL 312 F L + ++ + + + +E A FF + + G Y C Y + + S DVL Sbjct: 62 FGLFKPGEIAPLLF--RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVL 119 Query: 313 KIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSID 372 ++ VT+ P+ L+A P VV G NVSLRC G + + LY++G PLQ+ S Sbjct: 120 ELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQ 177 Query: 373 DNTSFFLNNVTYSDTGIYSCHY 394 F L + G YSC+Y Sbjct: 178 PWADFTL--LGARAPGTYSCYY 197 Score = 82.8 bits (203), Expect = 2e-15 Identities = 55/173 (31%), Positives = 78/173 (45%), Gaps = 9/173 (5%) Query: 684 PKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRM 740 PKP + A P G + LRC+ F L+K GE P+ A F ++ + Sbjct: 31 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 90 Query: 741 EDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNC 799 G Y C + P WS+PS+ LEL++ E P+P PVV PGA V+ C Sbjct: 91 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 150 Query: 800 STPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852 + ++MSF+LY++G R A P A +G G YSC Y+ Sbjct: 151 AGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGTYSCYYH 198 >gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens] Length = 252 Score = 144 bits (362), Expect = 7e-34 Identities = 79/187 (42%), Positives = 106/187 (56%), Gaps = 3/187 (1%) Query: 969 PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028 PKPWL A+P++VV G NVTL CR P + L K GE + +S F + + Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79 Query: 1029 SGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087 + G Y CCY PDW + QPS+ LELLVT LP+PSL+A PGP+V PG N++L+C Sbjct: 80 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139 Query: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147 G L + +FVL +EG PL+ + + ADF + R G YSC Y+ S P+ S Sbjct: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPSAPYVLSQ 197 Query: 1148 HSDSLEI 1154 S+ L I Sbjct: 198 RSEVLVI 204 Score = 123 bits (309), Expect = 1e-27 Identities = 73/174 (41%), Positives = 95/174 (54%), Gaps = 9/174 (5%) Query: 776 YPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFL 835 +PKP+ + VVTPG VT C P F L+K G EIA + + A F Sbjct: 19 HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--LFRDVSSELAEFF 75 Query: 836 IISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891 + V GG Y C Y + +WS+PSD +EL+VTE P+P+L+A PGPVV PG +V Sbjct: 76 LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135 Query: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945 LRC G + M F L +EG PLQ+R + ADF L +GA G YSC Y+ Sbjct: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 187 Score = 122 bits (306), Expect = 2e-27 Identities = 79/229 (34%), Positives = 119/229 (51%), Gaps = 8/229 (3%) Query: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAV 1124 PKP L AQP +V PG N+TL+C+ P F L K G PL + S A+F++ V Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79 Query: 1125 RGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183 GIY C Y D P S SD LE+ VT++ P+PSL A P + G +++L+C Sbjct: 80 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139 Query: 1184 RGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239 G L + FVL +G AP Q+ DF + + + G YSC Y + P + S+ Sbjct: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQ 197 Query: 1240 PSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWKKWPR 1288 S+ L ++ + + T GN+VR L +V+++LG ++ +W+ R Sbjct: 198 RSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 245 Score = 103 bits (258), Expect = 8e-22 Identities = 68/187 (36%), Positives = 88/187 (47%), Gaps = 3/187 (1%) Query: 871 FYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLH 930 ++PKP L AQP VV PG +V LRC+ RF L + G PL FR VS A+F L Sbjct: 18 YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 77 Query: 931 TVGAEDSGNYSCIYYETTMS-NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 V G Y C Y S S L + VT+ P+P L A P VV G NV+L Sbjct: 78 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137 Query: 990 WCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIK 1049 C G + + ++L++EG A +Q S F T + + G YSC YH + Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADF--TLLGARAPGTYSCYYHTPSAPYVL 195 Query: 1050 IQPSNTL 1056 Q S L Sbjct: 196 SQRSEVL 202 Score = 99.0 bits (245), Expect = 3e-20 Identities = 74/230 (32%), Positives = 109/230 (47%), Gaps = 16/230 (6%) Query: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380 PK WL A+P+ VV G NV+LRCR P L+K GE PL F D +S + FFL Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 77 Query: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 VT + GIY C Y W + + +EL+V ++ P+PSL A P V G ++L Sbjct: 78 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137 Query: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492 +C + F L E R + Q ++ DF + + + GTYSC Y + P Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 192 Query: 493 NIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWK 542 + S RSE L + + +Y +RL L ++ L ++ W+ Sbjct: 193 YVLSQRSEVLVISWEDSGSS-DYTRGNLVRLGLAGLVLISLGALVTFDWR 241 Score = 97.4 bits (241), Expect = 8e-20 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 6/188 (3%) Query: 130 PKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNL 189 PKP Q T PG NV + C F LFK G P+ ++ + +A F ++ + Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79 Query: 190 TPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248 TP G+Y C P +WS+PS+ L+L+V P+P+L A PGP++ PG +++LRC Sbjct: 80 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139 Query: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYY--DASYRGS 306 G + M+F L R E + ++ + + A+F L + G Y C+Y+ A Y S Sbjct: 140 AGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196 Query: 307 LLSDVLKI 314 S+VL I Sbjct: 197 QRSEVLVI 204 Score = 86.7 bits (213), Expect = 1e-16 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%) Query: 36 PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95 P+P L + P N+TL CR+P + +F L K + + F + Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 78 Query: 96 LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151 +T + G+YRCCY W WS+PS VLEL +LP+P PG NV++ Sbjct: 79 VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 138 Query: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211 C G L+++ F+L++EG A P+ Y+ A F++ L G Y C H P + S Sbjct: 139 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196 Query: 212 EPSNPL 217 + S L Sbjct: 197 QRSEVL 202 Score = 85.9 bits (211), Expect = 2e-16 Identities = 66/187 (35%), Positives = 92/187 (49%), Gaps = 12/187 (6%) Query: 590 PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLG 648 PKP L A+ + P N+TL CR+P + + F L K G + R S ++ A F L Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLE 77 Query: 649 ALTQSHTGSYHC----HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQELQL 701 +T + G Y C W S+PS+ LEL+ T+ LP+P + A P G + L Sbjct: 78 EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137 Query: 702 RCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKW 761 RC G L M F LY+EG P+Q + A FT+ + + G YSC HT P+ Sbjct: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVL 195 Query: 762 SEPSEPL 768 S+ SE L Sbjct: 196 SQRSEVL 202 Score = 84.0 bits (206), Expect = 9e-16 Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 10/177 (5%) Query: 222 AGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNE-AN 280 A +PKP L A P ++ PG ++ LRC+ P F L + ++ + + + +E A Sbjct: 16 ASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF--RDVSSELAE 73 Query: 281 FFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVLKIWVTDTFPKTWLLARPSAVVQMGQ 337 FF + + G Y C Y + + S DVL++ VT+ P+ L+A P VV G Sbjct: 74 FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133 Query: 338 NVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHY 394 NVSLRC G + + LY++G PLQ+ S F L + G YSC+Y Sbjct: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQPWADFTL--LGARAPGTYSCYY 186 Score = 82.8 bits (203), Expect = 2e-15 Identities = 55/173 (31%), Positives = 78/173 (45%), Gaps = 9/173 (5%) Query: 684 PKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRM 740 PKP + A P G + LRC+ F L+K GE P+ A F ++ + Sbjct: 20 PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79 Query: 741 EDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNC 799 G Y C + P WS+PS+ LEL++ E P+P PVV PGA V+ C Sbjct: 80 TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139 Query: 800 STPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852 + ++MSF+LY++G R A P A +G G YSC Y+ Sbjct: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGTYSCYYH 187 >gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B, member 5 isoform 3 [Homo sapiens] Length = 491 Score = 140 bits (352), Expect = 1e-32 Identities = 112/325 (34%), Positives = 153/325 (47%), Gaps = 31/325 (9%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA------HVPLQFRSVSGNSAD 926 PKPTL A+P V+ GK V L CQG + + L +EG PL+ G A Sbjct: 27 PKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE----PGAKAK 82 Query: 927 FLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQN 986 F + + + +G Y C YYET S S PL + T KP L SVV G + Sbjct: 83 FHIPSTVYDSAGRYRC-YYETPAG--WSEPSDPLELVATGVSRKPSLLIPQGSVVARGGS 139 Query: 987 VTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCC--- 1039 +TL CR V ++L+KEGE +Q G G F + +S + G+Y C Sbjct: 140 LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 199 Query: 1040 -YHPDWTSSIKIQPSNTLELLVTGLLPK-PSLLAQPGPMVAPGENMTLQCQGELPDSTFV 1097 P W++ PS+ L++L+ GL+P P+L QPGP VA GEN+TL CQ TF Sbjct: 200 NLSPRWSA-----PSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFF 254 Query: 1098 LLKEGAQEP----LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLE 1153 L KEGA P + + ++A+F M V G Y C + S P+ S+ S E Sbjct: 255 LTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQE 314 Query: 1154 IWVTDKPPKPSLSAWPSTMFKLGKD 1178 + V+ PSLS ST G + Sbjct: 315 LVVSGPSGDPSLSPTGSTPTPAGPE 339 Score = 136 bits (343), Expect = 1e-31 Identities = 105/301 (34%), Positives = 149/301 (49%), Gaps = 20/301 (6%) Query: 967 TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGE--ATSMQLWGSTSNDGAFP 1024 T PKP L+AEP+SV+ G+ VTLWC+GP+ Y L KEG A Q F Sbjct: 25 TLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFH 84 Query: 1025 ITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMT 1084 I + S GRY C Y T + +PS+ LEL+ TG+ KPSLL G +VA G ++T Sbjct: 85 IPSTVYDSAGRYRCYYE---TPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLT 141 Query: 1085 LQCQGELPDSTFVLLKEGAQEPLE---QQRPSGY-RADFWMPAVRGEDSGIYSCVYYLDS 1140 LQC+ ++ FVL KEG + ++ QQ +G +A+F + V G Y C + Sbjct: 142 LQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNL 201 Query: 1141 TPFAASNHSDSLEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGE 1199 +P S SD L+I + P P+LS P G+++TL C+ F L +G Sbjct: 202 SP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGA 260 Query: 1200 EAP--------QQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAG 1251 P Q + +F ++ V G Y C +++YP + S PS P ELV +G Sbjct: 261 AHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELV-VSG 319 Query: 1252 P 1252 P Sbjct: 320 P 320 Score = 134 bits (338), Expect = 4e-31 Identities = 112/336 (33%), Positives = 154/336 (45%), Gaps = 30/336 (8%) Query: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKNLTLWCRSPSGSTK 620 M ++ L+C GL G T + T PKP LWAE +A K +TLWC+ P T+ Sbjct: 1 MTLTLSVLICLGLSVG---PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPL-ETE 56 Query: 621 EFVLLKDGTGWIATR--PASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELV 678 E+ L K+G W R P +A F + + G Y C+ SEPS+ LELV Sbjct: 57 EYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 679 GTDILPKP---VISASPTIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLG----AVGR 731 T + KP + S RG L L+C+ + F LYKEGE + VQ G A Sbjct: 117 ATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLS 176 Query: 732 EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPK-PFFKTWASPVVT 790 +A FT+ + G Y C P +WS PS+PL+++I + P P P V Sbjct: 177 QANFTLGPVSRSHGGQYRCYGAHNLSP-RWSAPSDPLDILIAGLIPDIPALSVQPGPKVA 235 Query: 791 PGARVTFNCSTPHQHMSFILYKDGSE-----IASSDRSWASPGASAAHFLIISVGIGDGG 845 G VT C + HQ +F L K+G+ + S +S+ A F + V GG Sbjct: 236 SGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSY----RHQAEFSMSPVTSAQGG 291 Query: 846 NYSC----RYYDFSIWSEPSDPVELVVTEFYPKPTL 877 Y C R Y + + S PS P ELVV+ P+L Sbjct: 292 TYRCYSAIRSYPY-LLSSPSYPQELVVSGPSGDPSL 326 Score = 120 bits (302), Expect = 7e-27 Identities = 108/338 (31%), Positives = 148/338 (43%), Gaps = 29/338 (8%) Query: 683 LPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEG------EQEPVQQLGAVGREA 733 LPKP + A P RG+ + L C+G L + L KEG Q P++ G +A Sbjct: 26 LPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEP----GAKA 81 Query: 734 FFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGA 793 F I G Y C T P WSEPS+PLELV + KP VV G Sbjct: 82 KFHIPSTVYDSAGRYRCYYET---PAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGG 138 Query: 794 RVTFNCSTPHQHMSFILYKDGS-EIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852 +T C + + F+LYK+G ++ G S A+F + V GG Y C Y Sbjct: 139 SLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YG 197 Query: 853 DFSI---WSEPSDPVELVVTEFYPK-PTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQ 908 ++ WS PSDP+++++ P P L QPGP V G++V L CQ Q F L + Sbjct: 198 AHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTK 257 Query: 909 EG-AHVPLQFRS---VSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWV 964 EG AH PL +S + A+F + V + G Y C + S S P + V Sbjct: 258 EGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVV 317 Query: 965 TDTFPKPWLFAEPSSVVPMG---QNVTLWCRGPVHGVG 999 + P L S+ P G Q +T P G+G Sbjct: 318 SGPSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLG 355 Score = 115 bits (289), Expect = 2e-25 Identities = 96/309 (31%), Positives = 142/309 (45%), Gaps = 24/309 (7%) Query: 12 MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKF 68 M T +VL+ C+ +S+G + V P+P LW E A + +TLWC+ P Sbjct: 1 MTLTLSVLI-CLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYR 59 Query: 69 LLLKDKTQMTWIR----PSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELE 124 L DK + W R P + F I + +AG YRC Y GWS+PS LEL Sbjct: 60 L---DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELV 116 Query: 125 APGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVD---YQVPTG-T 180 A G KP I + G ++ + C + +F+L+KEG + V Q G + Sbjct: 117 ATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLS 176 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPK-PTLTAHPGPIMA 239 A F++ ++ G Y C + P WS PS+PL +++AGL P P L+ PGP +A Sbjct: 177 QANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVA 235 Query: 240 PGESLNLRCQGPIYGMTFALMRVEDLE-----KSFYHKKTIKNEANFFFQSLKIQDTGHY 294 GE++ L CQ TF L + KS Y ++ +++A F + G Y Sbjct: 236 SGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY--QSYRHQAEFSMSPVTSAQGGTY 293 Query: 295 LCFYYDASY 303 C+ SY Sbjct: 294 RCYSAIRSY 302 Score = 111 bits (278), Expect = 4e-24 Identities = 100/304 (32%), Positives = 131/304 (43%), Gaps = 15/304 (4%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+ G VT C P + + L K+G A ++ PGA A F Sbjct: 27 PKPTL--WAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAK-F 83 Query: 835 LIISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILR 894 I S G Y C Y + WSEPSDP+ELV T KP+LL G VV G S+ L+ Sbjct: 84 HIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLTLQ 143 Query: 895 CQGTFQGMRFALLQEGAHVPLQFR----SVSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950 C+ F L +EG H +Q + A+F L V G Y C Y +S Sbjct: 144 CRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAHNLS 202 Query: 951 NRGSYLSMPLMIWVTDTFPK-PWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA- 1008 R S S PL I + P P L +P V G+NVTL C+ + L KEG A Sbjct: 203 PRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAH 262 Query: 1009 ---TSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLP 1065 + S + F ++ ++ G Y C + PS EL+V+G Sbjct: 263 PPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSG 322 Query: 1066 KPSL 1069 PSL Sbjct: 323 DPSL 326 Score = 99.0 bits (245), Expect = 3e-20 Identities = 91/315 (28%), Positives = 131/315 (41%), Gaps = 30/315 (9%) Query: 216 PLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIY---------GMTFALMRVEDLE 266 P V AG PKPTL A P ++A G+ + L CQGP+ G+ +A R LE Sbjct: 17 PRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLE 76 Query: 267 KSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLL 326 +A F S G Y C YY+ S SD L++ T K LL Sbjct: 77 PGA--------KAKFHIPSTVYDSAGRYRC-YYETPAGWSEPSDPLELVATGVSRKPSLL 127 Query: 327 ARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQ--FLDATSIDDNTSFFLNNVTY 384 +VV G +++L+CR V LYK+GE +Q + +F L V+ Sbjct: 128 IPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSR 187 Query: 385 SDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVS 444 S G Y C+ PS L+ P P+LS P G+ +TL C+ Sbjct: 188 SHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSW 247 Query: 445 HPVLEFSLEWEE--------RETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWS 496 H + F L E + +Q + +F +S V GTY C + ++P + S Sbjct: 248 HQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLS 307 Query: 497 HRSEPLKLM--GPAG 509 S P +L+ GP+G Sbjct: 308 SPSYPQELVVSGPSG 322 Score = 98.6 bits (244), Expect = 4e-20 Identities = 68/196 (34%), Positives = 94/196 (47%), Gaps = 14/196 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRP--SGYRADF 1119 G LPKP+L A+P ++A G+ +TL CQG L + L KEG ++Q P G +A F Sbjct: 24 GTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 +P+ + +G Y C Y TP S SD LE+ T KPSL ++ G + Sbjct: 84 HIPSTVYDSAGRYRCYY---ETPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSL 140 Query: 1180 TLQCRGPLPGVEFVLEHDGE--------EAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQ 1231 TLQCR + FVL +GE + PQ +F + V G Y C Y Sbjct: 141 TLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRC-YGAH 199 Query: 1232 AYPDIWSEPSDPLELV 1247 WS PSDPL+++ Sbjct: 200 NLSPRWSAPSDPLDIL 215 Score = 80.1 bits (196), Expect = 1e-14 Identities = 68/207 (32%), Positives = 93/207 (44%), Gaps = 14/207 (6%) Query: 37 QPELWIESNYPQAPWENITLWCRSPSRISSKFLLLK----DKTQMTWIRPSHKTFQVSFL 92 +P L I A ++TL CRS F+L K D Q + +P Q +F Sbjct: 123 KPSLLIPQGSVVARGGSLTLQCRSDVGYDI-FVLYKEGEHDLVQGSGQQPQAGLSQANFT 181 Query: 93 IGALTESNAGLYRC--CYWKETGWSKPSKVLELEAPGQLPK-PIFWIQAETPALPGCNVN 149 +G ++ S+ G YRC + WS PS L++ G +P P +Q G NV Sbjct: 182 LGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVT 241 Query: 150 ILCHGWLQDLVFMLFKEGYAEPV-----DYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQ 204 +LC W Q F L KEG A P YQ A FS+ +T G Y C + I+ Sbjct: 242 LLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQ-SYRHQAEFSMSPVTSAQGGTYRCYSAIR 300 Query: 205 MLPTLWSEPSNPLKLVVAGLYPKPTLT 231 P L S PS P +LVV+G P+L+ Sbjct: 301 SYPYLLSSPSYPQELVVSGPSGDPSLS 327 >gi|46488946 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [Homo sapiens] Length = 410 Score = 130 bits (326), Expect = 1e-29 Identities = 101/330 (30%), Positives = 156/330 (47%), Gaps = 24/330 (7%) Query: 970 KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029 KP+L A P +VV GQ+VTL CR + + L KE +L+ + +F + ++ Sbjct: 28 KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRN-SFLMGPVT 86 Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089 G Y CC + + PSN + ++VTG+ KPSLLA PGP+V GE + LQC Sbjct: 87 PAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWS 146 Query: 1090 ELPDSTFVLLKEG-AQEPLE---QQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145 ++ F+L +EG ++PL Q +G + ++ M + +G Y C + P+ Sbjct: 147 DVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYEL 206 Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQF 1205 S SD L+I V KPSLSA P + G+++TL C + L + E + Sbjct: 207 SAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRL 266 Query: 1206 SE----DGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTV 1259 + +G F N G GNY C +A P WS+PSDPL PV+ Sbjct: 267 TAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPL-------PVS---VT 316 Query: 1260 GNIVRSSLIV---VVVVALGVVLAIEWKKW 1286 GN +++ VV++ ++L +W Sbjct: 317 GNSRHLHVLIGTSVVIIPFAILLFFLLHRW 346 Score = 103 bits (256), Expect = 1e-21 Identities = 93/296 (31%), Positives = 131/296 (44%), Gaps = 17/296 (5%) Query: 778 KPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYK-DGSEIASS-DRSWASPGASAAHFL 835 KPF W VV+ G VT C + F L K DG + +R + + FL Sbjct: 28 KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRNS------FL 81 Query: 836 IISVGIGDGGNYSC---RYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVI 892 + V G Y C + + WS PS+PV ++VT + KP+LLA PGP+V G++VI Sbjct: 82 MGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVI 141 Query: 893 LRCQGTFQGMRFALLQEG-AHVPLQFRSV---SGNSADFLLHTVGAEDSGNYSCIYYETT 948 L+C + RF L +EG PL+ +G+ ++ + + +G Y C T Sbjct: 142 LQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTH 201 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEA 1008 + S S PL I V + KP L A+P V G+NVTL C Y L +E EA Sbjct: 202 LPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEA 261 Query: 1009 TSMQLWGSTSNDGAFPITNISG--TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTG 1062 ++L +G F G T G Y C PS+ L + VTG Sbjct: 262 GELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSVTG 317 Score = 100 bits (249), Expect = 9e-21 Identities = 68/204 (33%), Positives = 99/204 (48%), Gaps = 9/204 (4%) Query: 52 ENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCY--- 108 +++TL CRS R+ L + M ++ F+ SFL+G +T ++AG YRCC Sbjct: 43 QHVTLQCRS--RLGFNEFSLSKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHP 100 Query: 109 WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGY 168 TGWS PS + + G KP G V + C ++ F+L +EG Sbjct: 101 HSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGI 160 Query: 169 AEP----VDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGL 224 E V G+ +S+ +TP G Y C + LP S PS+PL +VV GL Sbjct: 161 TEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGL 220 Query: 225 YPKPTLTAHPGPIMAPGESLNLRC 248 Y KP+L+A PGP + GE++ L C Sbjct: 221 YGKPSLSAQPGPTVQAGENVTLSC 244 Score = 93.2 bits (230), Expect = 1e-18 Identities = 86/297 (28%), Positives = 132/297 (44%), Gaps = 26/297 (8%) Query: 591 KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGAL 650 KP L A ++ +++TL CRS G EF L K+ G + R +F +G + Sbjct: 28 KPFLSAWPGTVVSEGQHVTLQCRSRLGFN-EFSLSKED-GMPVPELYNRIFRNSFLMGPV 85 Query: 651 TQSHTGSYHC---HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQELQLRCK 704 T +H G+Y C H S PS + ++ T + KP + A P G+ + L+C Sbjct: 86 TPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCW 145 Query: 705 GWLAGMGFALYKEGEQEP----VQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFK 760 + F L++EG E V QL G + +++ M G Y C P++ Sbjct: 146 SDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYE 205 Query: 761 WSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASS 820 S PS+PL++V+ +Y KP P V G VT +CS+ F +Y E + Sbjct: 206 LSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSS---RSLFDIYHLSREAEAG 262 Query: 821 DRSWAS----PGASAAHFLIISVGIGDGGNYSCRYYDF----SIWSEPSDPVELVVT 869 + + G A+F + V GGNY C + F WS+PSDP+ + VT Sbjct: 263 ELRLTAVLRVNGTFQANFPLGPV--THGGNYRC-FGSFRALPHAWSDPSDPLPVSVT 316 Score = 88.6 bits (218), Expect = 4e-17 Identities = 73/230 (31%), Positives = 99/230 (43%), Gaps = 10/230 (4%) Query: 123 LEAP----GQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPT 178 LE P G KP T G +V + C L F L KE PV Sbjct: 16 LEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKED-GMPVPELYNR 74 Query: 179 GTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIM 238 F + +TP G Y C + PT WS PSNP+ ++V G++ KP+L AHPGP++ Sbjct: 75 IFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLV 134 Query: 239 APGESLNLRCQGPIYGMTFALMR---VEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295 GE++ L+C + F L R ED + ++ N+ + G Y Sbjct: 135 KSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYR 194 Query: 296 CF--YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC 343 CF Y S SD L I V + K L A+P VQ G+NV+L C Sbjct: 195 CFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSC 244 Score = 82.8 bits (203), Expect = 2e-15 Identities = 86/325 (26%), Positives = 141/325 (43%), Gaps = 16/325 (4%) Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286 KP L+A PG +++ G+ + L+C+ + F+L + + + + + +N +F + Sbjct: 28 KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRN--SFLMGPV 85 Query: 287 KIQDTGHY-LCFYYDASYRG-SLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344 G Y C + S G S S+ + I VT K LLA P +V+ G+ V L+C Sbjct: 86 TPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCW 145 Query: 345 GPVDGVGLALYKKG-EDKPLQFL-DATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402 V L+++G + PL+ + ++ + +T + G Y C +T Sbjct: 146 SDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYE 205 Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEWE--ERE 458 + ++++VV KPSLSA P + G+ +TL C R + S E E E Sbjct: 206 LSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELR 265 Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYV 516 VNG F + G T G Y C P+ WS S+PL P + Sbjct: 266 LTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPL----PVSVTGNSRH 321 Query: 517 LNEAIRLSLIMQLVALLLVVLWIRW 541 L+ I S+++ A+LL L RW Sbjct: 322 LHVLIGTSVVIIPFAILLFFLLHRW 346 Score = 44.3 bits (103), Expect = 8e-04 Identities = 50/182 (27%), Positives = 75/182 (41%), Gaps = 12/182 (6%) Query: 52 ENITLWCRSPSRISSKFLLLKD---KTQMTWIRPSHKT-FQVSFLIGALTESNAGLYRCC 107 E + L C S R +FLL ++ + + + H QV++ +G +T + AG YRC Sbjct: 138 ETVILQCWSDVRFE-RFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRC- 195 Query: 108 YWKETGW----SKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFML 163 + T S PS L++ G KP Q G NV + C ++ L Sbjct: 196 FGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255 Query: 164 FKEGYAEPVDYQVPTGTMAIFSID-NLTPEDEGV-YICRTHIQMLPTLWSEPSNPLKLVV 221 +E A + F + L P G Y C + LP WS+PS+PL + V Sbjct: 256 SREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSV 315 Query: 222 AG 223 G Sbjct: 316 TG 317 >gi|208879429 hypothetical LOC441864 [Homo sapiens] Length = 271 Score = 128 bits (322), Expect = 3e-29 Identities = 87/216 (40%), Positives = 108/216 (50%), Gaps = 8/216 (3%) Query: 967 TFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEAT-SMQLWGSTSNDGAFPI 1025 + PKP L A PSSVVP NVTL C P GV ++L K G S + ST F + Sbjct: 25 SLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHL 84 Query: 1026 TNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTL 1085 N+ + G Y+C Y+ + I Q S+ L LLVTG L KP L V G +TL Sbjct: 85 NNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTL 144 Query: 1086 QCQGELPDSTFV-----LLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDS 1140 QCQ D FV LLK G P++ Q P+G DF + V D+G YSC+YY Sbjct: 145 QCQKR--DQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTK 202 Query: 1141 TPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLG 1176 +PF AS SD LEI VT P S + +LG Sbjct: 203 SPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLG 238 Score = 105 bits (261), Expect = 4e-22 Identities = 73/195 (37%), Positives = 99/195 (50%), Gaps = 8/195 (4%) Query: 777 PKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLI 836 PKP W S VV + VT C TP + +SF+L K G + S ++ GA A F + Sbjct: 27 PKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGA--AEFHL 84 Query: 837 ISVGIGDGGNYSCRYYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 ++ + + G Y+C YY + I S+ SD + L+VT KP L V G V L Sbjct: 85 NNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTL 144 Query: 894 RCQGT---FQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMS 950 +CQ F + FALL+ G P+Q +S +G DF L V A D+GNYSC+YY+T Sbjct: 145 QCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSP 204 Query: 951 NRGSYLSMPLMIWVT 965 S S L I VT Sbjct: 205 FWASEPSDQLEILVT 219 Score = 104 bits (260), Expect = 5e-22 Identities = 77/235 (32%), Positives = 111/235 (47%), Gaps = 16/235 (6%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEG----AQEPLEQQRPSGYRA 1117 G LPKPSL A P +V N+TL+C +FVL K G + +PL+ + A Sbjct: 24 GSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGA---A 80 Query: 1118 DFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGK 1177 +F + ++ ++G Y+C YY ++P S SD L + VT KP L + G Sbjct: 81 EFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGG 140 Query: 1178 DITLQCRGP---LPGVEFVLEHDGEEAPQQF----SEDGDFVINNVEGKGIGNYSCSYRL 1230 +TLQC+ + F L G +P Q ++ DF + +V GNYSC Y Sbjct: 141 RVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQ 200 Query: 1231 QAYPDIWSEPSDPLELVGAA--GPVAQECTVGNIVRSSLIVVVVVALGVVLAIEW 1283 P SEPSD LE++ G + ++GN VR L V+VV +G L W Sbjct: 201 TKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAW 255 Score = 90.9 bits (224), Expect = 7e-18 Identities = 67/201 (33%), Positives = 94/201 (46%), Gaps = 13/201 (6%) Query: 679 GTDILPKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGE-QEPVQQLGAVGREAF 734 G LPKP +SA P+ + LRC G+ F L K G E + L + A Sbjct: 22 GDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAE 81 Query: 735 FTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGAR 794 F + ++ ++ G Y+C + + P S+ S+ L L++ KPF +T+ VT G R Sbjct: 82 FHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGR 141 Query: 795 VTFNCSTPHQ---HMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRY 851 VT C Q + F L K G+ S SP F ++ V GD GNYSC Y Sbjct: 142 VTLQCQKRDQLFVPIMFALLKAGT---PSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMY 198 Query: 852 YDFS--IW-SEPSDPVELVVT 869 Y W SEPSD +E++VT Sbjct: 199 YQTKSPFWASEPSDQLEILVT 219 Score = 82.0 bits (201), Expect = 3e-15 Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 14/198 (7%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHV--PLQFRSVSGNSADFLLH 930 PKP+L A P VV +V LRC +G+ F L + G + P S G +A+F L+ Sbjct: 27 PKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEG-AAEFHLN 85 Query: 931 TVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLW 990 + ++G Y+C YY + S S L++ VT KP+L V G VTL Sbjct: 86 NLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQ 145 Query: 991 CRGPVH---GVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYH----PD 1043 C+ + + L K G + +QL + F + +++ G YSC Y+ P Sbjct: 146 CQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPF 205 Query: 1044 WTSSIKIQPSNTLELLVT 1061 W S +PS+ LE+LVT Sbjct: 206 WAS----EPSDQLEILVT 219 Score = 81.3 bits (199), Expect = 6e-15 Identities = 71/241 (29%), Positives = 100/241 (41%), Gaps = 18/241 (7%) Query: 319 TFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKG----EDKPLQFLDATSIDDN 374 + PK L A PS+VV NV+LRC P GV L K G KPL S + Sbjct: 25 SLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLD-----STEGA 79 Query: 375 TSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLG 434 F LNN+ + G Y+C Y I + + L+V KP L + G Sbjct: 80 AEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAG 139 Query: 435 KAITLQC----RVSHPVLEFSLEWEERETFQKFSVNG---DFIISNVDGKGTGTYSCSYR 487 +TLQC ++ P++ L+ Q S G DF + +V G YSC Y Sbjct: 140 GRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYY 199 Query: 488 VETHPNIWSHRSEPLKLM--GPAGYLTWNYVLNEAIRLSLIMQLVALLLVVLWIRWKCRR 545 P S S+ L+++ P G + NY L +RL L +V ++ L W R Sbjct: 200 QTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRN 259 Query: 546 L 546 + Sbjct: 260 V 260 Score = 79.7 bits (195), Expect = 2e-14 Identities = 65/215 (30%), Positives = 98/215 (45%), Gaps = 13/215 (6%) Query: 568 ALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKD 627 +LLC LC G + +P P W + P N+TL C +P+ FVL K Sbjct: 7 SLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPAN--SNVTLRCWTPARGVS-FVLRKG 63 Query: 628 GTGWIATRPA-SEQVRAAFPLGALTQSHTGSYHCHSWEEMA---VSEPSEALELVGTDIL 683 G + +P S + A F L L + G Y C + + + +S+ S+ L L+ T L Sbjct: 64 GIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHL 123 Query: 684 PKPVISA---SPTIRGQELQLRCKG---WLAGMGFALYKEGEQEPVQQLGAVGREAFFTI 737 KP + G + L+C+ + FAL K G P+Q G+E F++ Sbjct: 124 SKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSL 183 Query: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVI 772 + D GNYSC + K PF SEPS+ LE+++ Sbjct: 184 VDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILV 218 Score = 78.6 bits (192), Expect = 4e-14 Identities = 62/222 (27%), Positives = 97/222 (43%), Gaps = 7/222 (3%) Query: 223 GLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFF 282 G PKP+L+A P ++ ++ LRC P G++F L + + +S + + A F Sbjct: 24 GSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFH 83 Query: 283 FQSLKIQDTGHYLCFYY--DASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVS 340 +LK+++ G Y C YY + + S SDVL + VT K +L V G V+ Sbjct: 84 LNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVT 143 Query: 341 LRCRGPVD---GVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLT 397 L+C+ + AL K G P+Q + F L +VT D G YSC Y T Sbjct: 144 LQCQKRDQLFVPIMFALLKAGTPSPIQL--QSPAGKEIDFSLVDVTAGDAGNYSCMYYQT 201 Query: 398 WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439 + +E++V P S + +LG A + Sbjct: 202 KSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVI 243 Score = 69.7 bits (169), Expect = 2e-11 Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 15/214 (7%) Query: 20 LFCIRMSLGMTSIVMD---PQPEL--WIESNYPQAPWENITLWCRSPSRISSKFLLLKDK 74 L C R+ +G D P+P L W S P N+TL C +P+R S F+L K Sbjct: 8 LLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPAN--SNVTLRCWTPARGVS-FVLRKGG 64 Query: 75 TQMTWIRPSHKTFQVS-FLIGALTESNAGLYRCCYWKETG---WSKPSKVLELEAPGQLP 130 + +P T + F + L NAG Y C Y+++ S+ S VL L G L Sbjct: 65 IILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLS 124 Query: 131 KPIFWIQAETPALPGCNVNILCHGWLQ---DLVFMLFKEGYAEPVDYQVPTGTMAIFSID 187 KP G V + C Q ++F L K G P+ Q P G FS+ Sbjct: 125 KPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLV 184 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVV 221 ++T D G Y C + P SEPS+ L+++V Sbjct: 185 DVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILV 218 Score = 58.9 bits (141), Expect = 3e-08 Identities = 57/202 (28%), Positives = 87/202 (43%), Gaps = 17/202 (8%) Query: 127 GQLPKPIF--WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA----EPVDYQVPTGT 180 G LPKP W + PA NV + C + + F+L K G +P+D T Sbjct: 24 GSLPKPSLSAWPSSVVPA--NSNVTLRCWTPARGVSFVLRKGGIILESPKPLD---STEG 78 Query: 181 MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAP 240 A F ++NL + G Y C + + P + S+ S+ L L+V G KP L + + Sbjct: 79 AAEFHLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTA 138 Query: 241 GESLNLRCQGP---IYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCF 297 G + L+CQ + FAL++ + E +F + D G+Y C Sbjct: 139 GGRVTLQCQKRDQLFVPIMFALLKA-GTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCM 197 Query: 298 YYD--ASYRGSLLSDVLKIWVT 317 YY + + S SD L+I VT Sbjct: 198 YYQTKSPFWASEPSDQLEILVT 219 >gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like receptor, partial [Homo sapiens] Length = 256 Score = 119 bits (299), Expect = 1e-26 Identities = 90/248 (36%), Positives = 117/248 (47%), Gaps = 18/248 (7%) Query: 862 DPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEG------AHVPL 915 DP V PKPTL A+PG V+ G V LRCQG+ + + L +E +P Sbjct: 16 DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75 Query: 916 QFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFA 975 + F + ++ E +G Y CIY T S S PL + VT + KP L A Sbjct: 76 ELVK----KGQFPILSITWEHAGRYCCIYGSHTAGLSES--SDPLELVVT-AYSKPTLSA 128 Query: 976 EPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSND-----GAFPITNISG 1030 PS VV G NVT+ C V G+IL KEGE Q S S+ F + +S Sbjct: 129 LPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSP 188 Query: 1031 TSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGE 1090 + Y C + + PS+ L LLV G+ KPSL QPGP+VAPGE +T QC + Sbjct: 189 SRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSD 248 Query: 1091 LPDSTFVL 1098 FVL Sbjct: 249 PGYDRFVL 256 Score = 112 bits (280), Expect = 2e-24 Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 17/258 (6%) Query: 565 IVTALLCCGLCNGVLIEETEIVM-PTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFV 623 I+T L+C GL L T + P PKP LWAE + +TL C+ S T+E+ Sbjct: 4 ILTVLICLGLS---LDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYH 59 Query: 624 LLKDGTG--WIATRPASEQVRAAFPLGALTQSHTGSYHC-HSWEEMAVSEPSEALELVGT 680 L ++ WI P + FP+ ++T H G Y C + +SE S+ LELV T Sbjct: 60 LYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVT 119 Query: 681 DILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR-----E 732 KP +SA P+ G + ++C +A GF L KEGE E Q L + Sbjct: 120 -AYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSR 178 Query: 733 AFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 A F++ + +Y C + + P+ WS PS+ L L++ + KP PVV PG Sbjct: 179 AIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPG 238 Query: 793 ARVTFNCSTPHQHMSFIL 810 ++TF C + + F+L Sbjct: 239 EKLTFQCGSDPGYDRFVL 256 Score = 110 bits (276), Expect = 7e-24 Identities = 84/237 (35%), Positives = 114/237 (48%), Gaps = 18/237 (7%) Query: 969 PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLW-----GSTSNDGAF 1023 PKP L+AEP SV+ G VTL C+G + Y L++E + LW G F Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTA---LWITRIPQELVKKGQF 83 Query: 1024 PITNISGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENM 1083 PI +I+ GRY CC + T+ + + S+ LEL+VT KP+L A P P+V G N+ Sbjct: 84 PILSITWEHAGRY-CCIYGSHTAGLS-ESSDPLELVVTAY-SKPTLSALPSPVVTSGGNV 140 Query: 1084 TLQCQGELPDSTFVLLKEGAQEPLE-----QQRPSGYRADFWMPAVRGEDSGIYSCVYYL 1138 T+QC ++ F+L KEG E + RA F + V Y C Y Sbjct: 141 TIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYD 200 Query: 1139 DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVE-FVL 1194 P+ S SD L + V KPSLS P + G+ +T QC G PG + FVL Sbjct: 201 SRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC-GSDPGYDRFVL 256 Score = 95.1 bits (235), Expect = 4e-19 Identities = 80/229 (34%), Positives = 108/229 (47%), Gaps = 25/229 (10%) Query: 683 LPKPVISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQ-----EPVQQLGAVGREAF 734 LPKP + A P +G + LRC+G L + LY+E + Q+L G+ Sbjct: 26 LPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQ--- 82 Query: 735 FTIQRMEDKDEGNYSC--RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPG 792 F I + + G Y C +HT SE S+PLELV+ Y KP SPVVT G Sbjct: 83 FPILSITWEHAGRYCCIYGSHTAGL----SESSDPLELVVTA-YSKPTLSALPSPVVTSG 137 Query: 793 ARVTFNCSTPHQHMSFILYKDGSEI---ASSDRSWASPGASAAHFLIISVGIGDGGNYSC 849 VT C + FIL K+G + + S A G+S A F + V +Y C Sbjct: 138 GNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHAR-GSSRAIFSVGPVSPSRRWSYRC 196 Query: 850 RYYDFS---IWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRC 895 YD +WS PSD + L+V KP+L QPGPVV PG+ + +C Sbjct: 197 YGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245 Score = 93.6 bits (231), Expect = 1e-18 Identities = 75/241 (31%), Positives = 108/241 (44%), Gaps = 13/241 (5%) Query: 19 LLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKT 75 +L C+ +SL + V P+P LW E +TL C+ S + ++ L ++K Sbjct: 7 VLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQG-SLETQEYHLYREKK 65 Query: 76 QMTWIR--PSHKTFQVSFLIGALTESNAGLYRCCYWKET-GWSKPSKVLELEAPGQLPKP 132 WI P + F I ++T +AG Y C Y T G S+ S LEL KP Sbjct: 66 TALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTAY-SKP 124 Query: 133 IFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDY-----QVPTGTMAIFSID 187 G NV I C + F+L KEG E + AIFS+ Sbjct: 125 TLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVG 184 Query: 188 NLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLR 247 ++P Y C + P +WS PS+ L L+V G+ KP+L+ PGP++APGE L + Sbjct: 185 PVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQ 244 Query: 248 C 248 C Sbjct: 245 C 245 Score = 89.0 bits (219), Expect = 3e-17 Identities = 72/231 (31%), Positives = 106/231 (45%), Gaps = 5/231 (2%) Query: 215 NPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYH-KK 273 +P V AG PKPTL A PG ++ G + LRCQG + + L R + + Sbjct: 16 DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQ 75 Query: 274 TIKNEANFFFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVV 333 + + F S+ + G Y C Y + S SD L++ VT + K L A PS VV Sbjct: 76 ELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVT-AYSKPTLSALPSPVV 134 Query: 334 QMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTS---FFLNNVTYSDTGIY 390 G NV+++C V G L K+GED+ Q L++ S +S F + V+ S Y Sbjct: 135 TSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSY 194 Query: 391 SCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC 441 C+ + + + + L+V KPSLS P V G+ +T QC Sbjct: 195 RCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245 Score = 79.7 bits (195), Expect = 2e-14 Identities = 64/197 (32%), Positives = 93/197 (47%), Gaps = 14/197 (7%) Query: 1062 GLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGY--RADF 1119 G LPKP+L A+PG ++ G +TL+CQG L + L +E + P + F Sbjct: 24 GPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQF 83 Query: 1120 WMPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDI 1179 + ++ E +G Y C+Y S S SD LE+ VT KP+LSA PS + G ++ Sbjct: 84 PILSITWEHAGRYCCIY--GSHTAGLSESSDPLELVVT-AYSKPTLSALPSPVVTSGGNV 140 Query: 1180 TLQCRGPLPGVEFVLEHDGE-EAPQ--------QFSEDGDFVINNVEGKGIGNYSCSYRL 1230 T+QC + F+L +GE E PQ + S F + V +Y C Sbjct: 141 TIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYD 200 Query: 1231 QAYPDIWSEPSDPLELV 1247 P +WS PSD L L+ Sbjct: 201 SRAPYVWSLPSDLLGLL 217 Score = 76.3 bits (186), Expect = 2e-13 Identities = 69/223 (30%), Positives = 93/223 (41%), Gaps = 12/223 (5%) Query: 777 PKPFFKTWASP--VVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHF 834 PKP WA P V+T G+ VT C + + LY++ R F Sbjct: 27 PKPTL--WAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRI-PQELVKKGQF 83 Query: 835 LIISVGIGDGGNYSCRYYDFSIW-SEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVIL 893 I+S+ G Y C Y + SE SDP+ELVVT Y KPTL A P PVV G +V + Sbjct: 84 PILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA-YSKPTLSALPSPVVTSGGNVTI 142 Query: 894 RCQGTFQGMRFALLQEGAHVPLQ-----FRSVSGNSADFLLHTVGAEDSGNYSCIYYETT 948 +C F L +EG Q + + A F + V +Y C Y++ Sbjct: 143 QCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSR 202 Query: 949 MSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWC 991 S S L + V KP L +P VV G+ +T C Sbjct: 203 APYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQC 245 Score = 52.4 bits (124), Expect = 3e-06 Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 8/96 (8%) Query: 1161 PKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEA------PQQFSEDGDFVIN 1214 PKP+L A P ++ G +TL+C+G L E+ L + + A PQ+ + G F I Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86 Query: 1215 NVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAA 1250 ++ + G Y C Y ++ SE SDPLELV A Sbjct: 87 SITWEHAGRYCCIYG--SHTAGLSESSDPLELVVTA 120 Score = 42.7 bits (99), Expect = 0.002 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 8/93 (8%) Query: 419 PKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETF------QKFSVNGDFIIS 472 PKP+L A P +V G +TL+C+ S E+ L E++ Q+ G F I Sbjct: 27 PKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPIL 86 Query: 473 NVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505 ++ + G Y C Y +H S S+PL+L+ Sbjct: 87 SITWEHAGRYCCIY--GSHTAGLSESSDPLELV 117 >gi|134268644 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 precursor [Homo sapiens] Length = 444 Score = 118 bits (295), Expect = 4e-26 Identities = 100/338 (29%), Positives = 155/338 (45%), Gaps = 26/338 (7%) Query: 970 KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029 KP+L A PS+VVP G +VTL C ++L+KE + + ++ +F ++ ++ Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-DRIHIPIFHGRIFQESFNMSPVT 86 Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089 G Y+C + + PSN + ++VTG KPSLLA PGP+V GE + LQC Sbjct: 87 TAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146 Query: 1090 ELPDSTFVLLKEG-AQEP---LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145 ++ F L KEG +++P + Q +A+F + + +G Y C + TP+ Sbjct: 147 DIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206 Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----EEA 1201 S SD L+I VT KPSLSA P + G+ +TL C + L +G Sbjct: 207 SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRL 266 Query: 1202 PQQFSEDGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAG-------- 1251 P + F + G G Y C + P WS+PSDPL LV G Sbjct: 267 PAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL-LVSVTGNPSSSWPS 325 Query: 1252 PVAQECTVGN------IVRSSLIVVVVVALGVVLAIEW 1283 P GN ++ +S+++++ + L L W Sbjct: 326 PTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLW 363 Score = 107 bits (266), Expect = 1e-22 Identities = 100/311 (32%), Positives = 138/311 (44%), Gaps = 23/311 (7%) Query: 685 KPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRME 741 KP +SA P+ RG + LRC F LYKE G + +E+F + + Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESF-NMSPVT 86 Query: 742 DKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCST 801 GNY+CR P WS PS P+ +++ + KP P+V G RV C + Sbjct: 87 TAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146 Query: 802 PHQHMSFILYKDG-SEIASSDRSWASPGASAAHFLIISVGIGDGGNYSC----RYYDFSI 856 F L+K+G S+ S G S A+F I + + G Y C + + + Sbjct: 147 DIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206 Query: 857 WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-GAH--- 912 S PSDP+++VVT Y KP+L AQPGP V G+SV L C + L +E GAH Sbjct: 207 -SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265 Query: 913 VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT----DTF 968 +P + ADF L A G Y C S S PL++ VT ++ Sbjct: 266 LPAVRKVNRTFQADFPLGP--ATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323 Query: 969 PKPWLFAEPSS 979 P P EPSS Sbjct: 324 PSP---TEPSS 331 Score = 100 bits (248), Expect = 1e-20 Identities = 96/303 (31%), Positives = 133/303 (43%), Gaps = 31/303 (10%) Query: 778 KPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWAS---PGASAAHF 834 KPF W S VV G VT C H+ +F+LYK+ DR F Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKE-------DRIHIPIFHGRIFQESF 80 Query: 835 LIISVGIGDGGNYSCRY---YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891 + V GNY+CR + + WS PS+PV ++VT + KP+LLA PGP+V G+ V Sbjct: 81 NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERV 140 Query: 892 ILRCQGTFQGMRFALLQEG-----AHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYE 946 IL+C F L +EG + + Q + A+F + + +G Y C Sbjct: 141 ILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVSKANFSIGPMMLALAGTYRCYGSV 199 Query: 947 TTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEG 1006 T + S S PL I VT + KP L A+P V G++VTL C Y L +EG Sbjct: 200 THTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259 Query: 1007 EATSMQLWGSTSNDGAFPITNISG--TSMGRYSCC----YHP-DWTSSIKIQPSNTLELL 1059 A +L + F G T G Y C + P +W+ PS+ L + Sbjct: 260 GAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWS-----DPSDPLLVS 314 Query: 1060 VTG 1062 VTG Sbjct: 315 VTG 317 Score = 90.1 bits (222), Expect = 1e-17 Identities = 92/319 (28%), Positives = 134/319 (42%), Gaps = 52/319 (16%) Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTM--AIFSIDNLTPE 192 W A P G +V + CH + FML+KE + + + G + F++ +T Sbjct: 34 WPSAVVPR--GGHVTLRCHYRHRFNNFMLYKE---DRIHIPIFHGRIFQESFNMSPVTTA 88 Query: 193 DEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPI 252 G Y CR PT WS PSNP+ ++V G + KP+L AHPGP++ GE + L+C I Sbjct: 89 HAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDI 148 Query: 253 YGMTFALMRVEDLEKSFYHKKTIK--------------NEANFFFQSLKIQDTGHYLCF- 297 E F HK+ I ++ANF + + G Y C+ Sbjct: 149 M-----------FEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYG 197 Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC--RGPVDGVGLAL 354 Y+ S SD L I VT + K L A+P VQ G++V+L C R D L+ Sbjct: 198 SVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSR 257 Query: 355 YKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSC-----HYLLTWKTSIRMPSHNT 409 ++ L + + F L T+ G Y C H W PS Sbjct: 258 EGGAHERRLPAVRKVNRTFQADFPLGPATHG--GTYRCFGSFRHSPYEWSD----PS--- 308 Query: 410 VELMVVDKPPKPSLSAWPS 428 + ++V PS S+WPS Sbjct: 309 -DPLLVSVTGNPS-SSWPS 325 Score = 81.6 bits (200), Expect = 4e-15 Identities = 79/282 (28%), Positives = 114/282 (40%), Gaps = 12/282 (4%) Query: 53 NITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRC---CYW 109 ++TL C R ++ L +D+ + + FQ SF + +T ++AG Y C Sbjct: 44 HVTLRCHYRHRFNNFMLYKEDRIHIPIFHG--RIFQESFNMSPVTTAHAGNYTCRGSHPH 101 Query: 110 KETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA 169 TGWS PS + + G KP G V + C + F L KEG + Sbjct: 102 SPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGIS 161 Query: 170 EPVDY---QVPTG-TMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLY 225 + Q+ G + A FSI + G Y C + P S PS+PL +VV G Y Sbjct: 162 KDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPY 221 Query: 226 PKPTLTAHPGPIMAPGESLNLRCQG-PIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQ 284 KP+L+A PGP + GES+ L C Y M E+ + + F Sbjct: 222 EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFP 281 Query: 285 SLKIQDTGHYLCF--YYDASYRGSLLSDVLKIWVTDTFPKTW 324 G Y CF + + Y S SD L + VT +W Sbjct: 282 LGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323 Score = 80.1 bits (196), Expect = 1e-14 Identities = 71/260 (27%), Positives = 115/260 (44%), Gaps = 38/260 (14%) Query: 644 AFPLGALTQSHTGSYHC---HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQ 697 +F + +T +H G+Y C H S PS + ++ T KP + A P G+ Sbjct: 79 SFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGE 138 Query: 698 ELQLRCKGWLAGMGFALYKEG-EQEPVQQLGAVG---REAFFTIQRMEDKDEGNYSCRTH 753 + L+C + F L+KEG ++P + +G + +A F+I M G Y C Sbjct: 139 RVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGS 198 Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKD 813 P++ S PS+PL++V+ Y KP P V G VT +CS+ + + L ++ Sbjct: 199 VTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSRE 258 Query: 814 GS-------EIASSDRSWAS--PGASAAHFLIISVGIGDGGNYSC----RYYDFSIWSEP 860 G + +R++ + P A H GG Y C R+ + WS+P Sbjct: 259 GGAHERRLPAVRKVNRTFQADFPLGPATH----------GGTYRCFGSFRHSPYE-WSDP 307 Query: 861 SDPVELVVT----EFYPKPT 876 SDP+ + VT +P PT Sbjct: 308 SDPLLVSVTGNPSSSWPSPT 327 Score = 74.3 bits (181), Expect = 7e-13 Identities = 75/286 (26%), Positives = 116/286 (40%), Gaps = 12/286 (4%) Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286 KP L+A P ++ G + LRC F L + + + +H + + N + Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESFNM--SPV 85 Query: 287 KIQDTGHYLC--FYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344 G+Y C + + S S+ + I VT K LLA P +V+ G+ V L+C Sbjct: 86 TTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145 Query: 345 GPVDGVGLALYKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402 + L+K+G K L D +F + + + G Y C+ +T Sbjct: 146 SDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQ 205 Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEW--EERE 458 + ++++V KPSLSA P + G+++TL C R S+ + S E ER Sbjct: 206 LSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265 Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPL 502 VN F G T GTY C P WS S+PL Sbjct: 266 LPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL 311 Score = 50.4 bits (119), Expect = 1e-05 Identities = 74/290 (25%), Positives = 112/290 (38%), Gaps = 40/290 (13%) Query: 420 KPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEER---ETFQKFSVNGDFIISNVDG 476 KP LSAWPS V G +TL+C H F L E+R F F +S V Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESFNMSPVTT 87 Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLS----LIMQLVAL 532 G Y+C P WS S P+ +M + + + + + +I+Q + Sbjct: 88 AHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSD 147 Query: 533 LLVVLWIRWKCRRLRIREAWLLGTAQ----------GVTMLFIVTALLCCGLCNGVLIE- 581 ++ + K + + L+G G ML + C G + Sbjct: 148 IMFEHFFLHK-EGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQL 206 Query: 582 -------ETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIAT 634 + + P KP L A+ + +++TL C S S S + L ++G Sbjct: 207 SAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRS-SYDMYHLSREGGAHERR 265 Query: 635 RPASEQV----RAAFPLGALTQSHTGSYHC-----HSWEEMAVSEPSEAL 675 PA +V +A FPLG T H G+Y C HS E S+PS+ L Sbjct: 266 LPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEW--SDPSDPL 311 Score = 47.4 bits (111), Expect = 9e-05 Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 12/154 (7%) Query: 642 RAAFPLGALTQSHTGSYHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIR--- 695 +A F +G + + G+Y C+ + +S PS+ L++V T KP +SA P + Sbjct: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236 Query: 696 GQELQLRCKGWLAGMGFALYKEG--EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTH 753 G+ + L C + + L +EG + + + V R G Y C Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGS 296 Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787 P++WS+PS+PL LV P +W SP Sbjct: 297 FRHSPYEWSDPSDPL-LVSVTGNPS---SSWPSP 326 >gi|134133244 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 [Homo sapiens] Length = 382 Score = 117 bits (294), Expect = 6e-26 Identities = 101/338 (29%), Positives = 152/338 (44%), Gaps = 23/338 (6%) Query: 970 KPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNIS 1029 KP+L A PS+VVP G +VTL C ++L+KE G +G F ++ ++ Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG-FNMSPVT 86 Query: 1030 GTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQG 1089 G Y+C + + PSN + ++VTG KPSLLA PGP+V GE + LQC Sbjct: 87 TAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146 Query: 1090 ELPDSTFVLLKEG-AQEP---LEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAA 1145 ++ F L KE +++P + Q +A+F + ++ +G Y C + TP+ Sbjct: 147 DIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQL 206 Query: 1146 SNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDG----EEA 1201 S SD L+I VT KPSLSA P + G+ +TL C + L +G Sbjct: 207 SAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRL 266 Query: 1202 PQQFSEDGDFVINNVEGKGI--GNYSCSYRLQAYPDIWSEPSDPLELVGAAG-------- 1251 P + F + G G Y C + P WS+PSDPL LV G Sbjct: 267 PAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL-LVSVTGNPSSSWPS 325 Query: 1252 PVAQECTVGNIVRSSLIV---VVVVALGVVLAIEWKKW 1286 P GN+ +++ VV + ++L +W Sbjct: 326 PTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLLHRW 363 Score = 117 bits (294), Expect = 6e-26 Identities = 99/307 (32%), Positives = 134/307 (43%), Gaps = 19/307 (6%) Query: 874 KPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGA-HVPLQFRSVSGNSADFLLHTV 932 KP L A P VV G V LRC + F L +E HVP+ + F + V Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG--FNMSPV 85 Query: 933 GAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTLWCR 992 +GNY+C S S P++I VT KP L A P +V G+ V L C Sbjct: 86 TTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145 Query: 993 GPVHGVGYILHKEGEATSMQLWGSTSNDGA----FPITNISGTSMGRYSCCYHPDWTSSI 1048 + + LHKE + +DG F I ++ G Y C T Sbjct: 146 SDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQ 205 Query: 1049 KIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQE--- 1105 PS+ L+++VTGL KPSL AQPGP V GE++TL C + L +EG Sbjct: 206 LSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265 Query: 1106 -PLEQQRPSGYRADFWM-PAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKP 1163 P ++ ++ADF + PA G G Y C +P+ S+ SD L + VT P Sbjct: 266 LPAVRKVNRTFQADFPLGPATHG---GTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPS-- 320 Query: 1164 SLSAWPS 1170 S+WPS Sbjct: 321 --SSWPS 325 Score = 105 bits (263), Expect = 2e-22 Identities = 100/311 (32%), Positives = 136/311 (43%), Gaps = 23/311 (7%) Query: 685 KPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRME 741 KP +SA P+ RG + LRC F LYKE G + +E F + + Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGF-NMSPVT 86 Query: 742 DKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCST 801 GNY+CR P WS PS P+ +++ + KP P+V G RV C + Sbjct: 87 TAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWS 146 Query: 802 PHQHMSFILYKDG-SEIASSDRSWASPGASAAHFLIISVGIGDGGNYSC----RYYDFSI 856 F L+K+ S+ S G S A+F I S+ G Y C + + + Sbjct: 147 DIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQL 206 Query: 857 WSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQE-GAH--- 912 S PSDP+++VVT Y KP+L AQPGP V G+SV L C + L +E GAH Sbjct: 207 -SAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265 Query: 913 VPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVT----DTF 968 +P + ADF L A G Y C S S PL++ VT ++ Sbjct: 266 LPAVRKVNRTFQADFPLGP--ATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323 Query: 969 PKPWLFAEPSS 979 P P EPSS Sbjct: 324 PSP---TEPSS 331 Score = 89.7 bits (221), Expect = 2e-17 Identities = 93/319 (29%), Positives = 134/319 (42%), Gaps = 52/319 (16%) Query: 135 WIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAI--FSIDNLTPE 192 W A P G +V + CH + FML+KE + + + G + F++ +T Sbjct: 34 WPSAVVPR--GGHVTLRCHYRHRFNNFMLYKE---DRIHVPIFHGRIFQEGFNMSPVTTA 88 Query: 193 DEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPI 252 G Y CR PT WS PSNP+ ++V G + KP+L AHPGP++ GE + L+C I Sbjct: 89 HAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDI 148 Query: 253 YGMTFALMRVEDLEKSFYHKKTIK--------------NEANFFFQSLKIQDTGHYLCF- 297 E F HK+ I ++ANF S+ G Y C+ Sbjct: 149 M-----------FEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG 197 Query: 298 -YYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRC--RGPVDGVGLAL 354 Y+ S SD L I VT + K L A+P VQ G++V+L C R D L+ Sbjct: 198 SVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSR 257 Query: 355 YKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSC-----HYLLTWKTSIRMPSHNT 409 ++ L + + F L T+ G Y C H W PS Sbjct: 258 EGGAHERRLPAVRKVNRTFQADFPLGPATHG--GTYRCFGSFRHSPYEWSD----PS--- 308 Query: 410 VELMVVDKPPKPSLSAWPS 428 + ++V PS S+WPS Sbjct: 309 -DPLLVSVTGNPS-SSWPS 325 Score = 81.6 bits (200), Expect = 4e-15 Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 12/282 (4%) Query: 53 NITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGALTESNAGLYRCCY---W 109 ++TL C R ++ L +D+ + + FQ F + +T ++AG Y C Sbjct: 44 HVTLRCHYRHRFNNFMLYKEDRIHVPIFHG--RIFQEGFNMSPVTTAHAGNYTCRGSHPH 101 Query: 110 KETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYA 169 TGWS PS + + G KP G V + C + F L KE + Sbjct: 102 SPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWIS 161 Query: 170 EPVDY---QVPTG-TMAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLY 225 + Q+ G + A FSI ++ G Y C + P S PS+PL +VV GLY Sbjct: 162 KDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLY 221 Query: 226 PKPTLTAHPGPIMAPGESLNLRCQG-PIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQ 284 KP+L+A PGP + GES+ L C Y M E+ + + F Sbjct: 222 EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFP 281 Query: 285 SLKIQDTGHYLCF--YYDASYRGSLLSDVLKIWVTDTFPKTW 324 G Y CF + + Y S SD L + VT +W Sbjct: 282 LGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSW 323 Score = 72.0 bits (175), Expect = 4e-12 Identities = 74/286 (25%), Positives = 116/286 (40%), Gaps = 12/286 (4%) Query: 227 KPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSL 286 KP L+A P ++ G + LRC F L + + + +H + + F + Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQE--GFNMSPV 85 Query: 287 KIQDTGHYLC--FYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCR 344 G+Y C + + S S+ + I VT K LLA P +V+ G+ V L+C Sbjct: 86 TTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERVILQCW 145 Query: 345 GPVDGVGLALYKKGEDKPLQFLDATSID--DNTSFFLNNVTYSDTGIYSCHYLLTWKTSI 402 + L+K+ K L D +F + ++ + G Y C+ +T Sbjct: 146 SDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQ 205 Query: 403 RMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQC--RVSHPVLEFSLEW--EERE 458 + ++++V KPSLSA P + G+++TL C R S+ + S E ER Sbjct: 206 LSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERR 265 Query: 459 TFQKFSVNGDFIISNVDGKGT--GTYSCSYRVETHPNIWSHRSEPL 502 VN F G T GTY C P WS S+PL Sbjct: 266 LPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPL 311 Score = 51.2 bits (121), Expect = 7e-06 Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 12/154 (7%) Query: 642 RAAFPLGALTQSHTGSYHCH---SWEEMAVSEPSEALELVGTDILPKPVISASPTIR--- 695 +A F +G++ ++ G+Y C+ + +S PS+ L++V T + KP +SA P + Sbjct: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236 Query: 696 GQELQLRCKGWLAGMGFALYKEG--EQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTH 753 G+ + L C + + L +EG + + + V R G Y C Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGS 296 Query: 754 TEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787 P++WS+PS+PL LV P +W SP Sbjct: 297 FRHSPYEWSDPSDPL-LVSVTGNPS---SSWPSP 326 Score = 48.5 bits (114), Expect = 4e-05 Identities = 73/294 (24%), Positives = 113/294 (38%), Gaps = 48/294 (16%) Query: 420 KPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEER---ETFQKFSVNGDFIISNVDG 476 KP LSAWPS V G +TL+C H F L E+R F F +S V Sbjct: 28 KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEGFNMSPVTT 87 Query: 477 KGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAIRLSLIMQLVALLLVV 536 G Y+C P WS S P+ +M + + + + +++ +++ Sbjct: 88 AHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHP----GPLVKSGERVILQ 143 Query: 537 LWIRWKCRRLRIREAW-------LLG------TAQGVTMLFIVTALLCCGLCNGVLIEET 583 W + + W L+G + ++ ++ AL C G + T Sbjct: 144 CWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYG-SVTHT 202 Query: 584 EIVMPTP-------------KPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTG 630 + P KP L A+ + +++TL C S S S + L ++G Sbjct: 203 PYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRS-SYDMYHLSREGGA 261 Query: 631 WIATRPASEQV----RAAFPLGALTQSHTGSYHC-----HSWEEMAVSEPSEAL 675 PA +V +A FPLG T H G+Y C HS E S+PS+ L Sbjct: 262 HERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEW--SDPSDPL 311 >gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens] Length = 339 Score = 117 bits (294), Expect = 6e-26 Identities = 105/326 (32%), Positives = 139/326 (42%), Gaps = 50/326 (15%) Query: 969 PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028 PKP L A PSS+VP+ + VTL C+GP G L++ + +S + + I + Sbjct: 26 PKPSLQALPSSLVPLEKPVTLRCQGPP---GVDLYRLEKLSSSRY----QDQAVLFIPAM 78 Query: 1029 SGTSMGRYSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQ 1088 + GRY C Y S+ PS+ LEL+ TG+ KPSL AQPGP V+ G ++TLQCQ Sbjct: 79 KRSLAGRYRCSYQ---NGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQ 135 Query: 1089 GELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNH 1148 F L KEG P + YRA F + V SG Y C + P+ S Sbjct: 136 TRYGFDQFALYKEGDPAPYKNPE-RWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAP 194 Query: 1149 SDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSED 1208 SD LE+ VT PS L P P EF EA + + Sbjct: 195 SDPLELVVTGTSVTPS---------------RLPTEPPSPVAEF------SEATAELTVS 233 Query: 1209 GDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELVGAAGPVAQECTVGNIVRSSLI 1268 + E S + P E AGP Q T GN+VR L Sbjct: 234 FTNEVFTTETSR-----------------SITASPKESDSPAGPARQYYTKGNLVRICLG 276 Query: 1269 VVVVVALGVVLAIEW-KKWPRLRTRG 1293 V+++ L LA +W + RLR RG Sbjct: 277 AVILIILAGFLAEDWHSRRKRLRHRG 302 Score = 90.5 bits (223), Expect = 1e-17 Identities = 82/275 (29%), Positives = 119/275 (43%), Gaps = 23/275 (8%) Query: 567 TALLCCGLCNGVLIEETEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLK 626 TAL C GLC G + ++ P PKP L A + + K +TL C+ P G + L K Sbjct: 6 TALFCLGLCLGRVPAQSG---PLPKPSLQALPSSLVPLEKPVTLRCQGPPG-VDLYRLEK 61 Query: 627 DGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKP 686 + + Q +A + A+ +S G Y C S PS+ LELV T + KP Sbjct: 62 LSS-------SRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKP 114 Query: 687 VISASP---TIRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRMEDK 743 +SA P G ++ L+C+ FALYKEG+ P + R A F I + Sbjct: 115 SLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYR-ASFPIITVTAA 173 Query: 744 DEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNCSTPH 803 G Y C + + + P+ WS PS+PLELV+ P P P F+ +T Sbjct: 174 HSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPS----RLPTEPPSPVAEFSEATAE 229 Query: 804 QHMSF----ILYKDGSEIASSDRSWASPGASAAHF 834 +SF + I +S + SP A + Sbjct: 230 LTVSFTNEVFTTETSRSITASPKESDSPAGPARQY 264 Score = 88.2 bits (217), Expect = 5e-17 Identities = 68/190 (35%), Positives = 89/190 (46%), Gaps = 13/190 (6%) Query: 1061 TGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFW 1120 +G LPKPSL A P +V + +TL+CQG + L K + +Q A + Sbjct: 22 SGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQDQ-------AVLF 74 Query: 1121 MPAVRGEDSGIYSCVYYLDSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDIT 1180 +PA++ +G Y C Y S S SD LE+ T KPSLSA P G D+T Sbjct: 75 IPAMKRSLAGRYRCSYQNGSL---WSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVT 131 Query: 1181 LQCRGPLPGVEFVLEHDGEEAPQQFSE---DGDFVINNVEGKGIGNYSCSYRLQAYPDIW 1237 LQC+ +F L +G+ AP + E F I V G Y C P +W Sbjct: 132 LQCQTRYGFDQFALYKEGDPAPYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLW 191 Query: 1238 SEPSDPLELV 1247 S PSDPLELV Sbjct: 192 SAPSDPLELV 201 Score = 86.3 bits (212), Expect = 2e-16 Identities = 69/206 (33%), Positives = 92/206 (44%), Gaps = 12/206 (5%) Query: 777 PKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLI 836 PKP + S +V VT C P G ++ ++ +S A I Sbjct: 26 PKPSLQALPSSLVPLEKPVTLRCQGP----------PGVDLYRLEKLSSSRYQDQAVLFI 75 Query: 837 ISVGIGDGGNYSCRYYDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQ 896 ++ G Y C Y + S+WS PSD +ELV T + KP+L AQPGP V G V L+CQ Sbjct: 76 PAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQ 135 Query: 897 GTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYL 956 + +FAL +EG P + A F + TV A SG Y C + + S Sbjct: 136 TRYGFDQFALYKEGDPAPYK-NPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAP 194 Query: 957 SMPLMIWVTDTFPKP-WLFAEPSSVV 981 S PL + VT T P L EP S V Sbjct: 195 SDPLELVVTGTSVTPSRLPTEPPSPV 220 Score = 85.5 bits (210), Expect = 3e-16 Identities = 72/224 (32%), Positives = 98/224 (43%), Gaps = 17/224 (7%) Query: 20 LFCIRMSLGMTSIVMDPQPELWIESNYPQA--PWEN-ITLWCRSPSRISSKFLLLKDKTQ 76 LFC+ + LG P P+ +++ P + P E +TL C+ P + D + Sbjct: 8 LFCLGLCLGRVPAQSGPLPKPSLQA-LPSSLVPLEKPVTLRCQGPPGV--------DLYR 58 Query: 77 MTWIRPSHKTFQVSFLIGALTESNAGLYRCCYWKETGWSKPSKVLELEAPGQLPKPIFWI 136 + + S Q I A+ S AG YRC Y + WS PS LEL A G KP Sbjct: 59 LEKLSSSRYQDQAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVFAKPSLSA 118 Query: 137 QAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVP-TGTMAIFSIDNLTPEDEG 195 Q G +V + C F L+KEG +P Y+ P A F I +T G Sbjct: 119 QPGPAVSSGGDVTLQCQTRYGFDQFALYKEG--DPAPYKNPERWYRASFPIITVTAAHSG 176 Query: 196 VYICRTHIQMLPTLWSEPSNPLKLVVAG--LYPKPTLTAHPGPI 237 Y C + P LWS PS+PL+LVV G + P T P P+ Sbjct: 177 TYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPV 220 Score = 79.3 bits (194), Expect = 2e-14 Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 50/328 (15%) Query: 222 AGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNEANF 281 +G PKP+L A P ++ + + LRCQGP L R+E L S Y +++A Sbjct: 22 SGPLPKPSLQALPSSLVPLEKPVTLRCQGP---PGVDLYRLEKLSSSRY-----QDQAVL 73 Query: 282 FFQSLKIQDTGHYLCFYYDASYRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSL 341 F ++K G Y C Y + S SL SD L++ T F K L A+P V G +V+L Sbjct: 74 FIPAMKRSLAGRYRCSYQNGSL-WSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132 Query: 342 RCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTS 401 +C+ ALYK+G+ P + + SF + VT + +G Y C+ + Sbjct: 133 QCQTRYGFDQFALYKEGDPAPYKNPERWY---RASFPIITVTAAHSGTYRCYSFSSRDPY 189 Query: 402 IRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEERETFQ 461 + + +EL+V PS L PV EFS Sbjct: 190 LWSAPSDPLELVVTGTSVTPS---------------RLPTEPPSPVAEFS---------- 224 Query: 462 KFSVNGDFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLMGPAGYLTWNYVLNEAI 521 + T S + V T S + P + PAG Y + Sbjct: 225 -------------EATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLV 271 Query: 522 RLSLIMQLVALLLVVLWIRWKCRRLRIR 549 R+ L ++ +L L W RR R+R Sbjct: 272 RICLGAVILIILAGFLAEDWHSRRKRLR 299 Score = 77.8 bits (190), Expect = 6e-14 Identities = 70/215 (32%), Positives = 95/215 (44%), Gaps = 32/215 (14%) Query: 683 LPKPVISASPTIR---GQELQLRCKGWLAGMGFALYKEGEQEPVQQLGA--VGREAFFTI 737 LPKP + A P+ + + LRC+G G LY+ +++L + +A I Sbjct: 25 LPKPSLQALPSSLVPLEKPVTLRCQG---PPGVDLYR------LEKLSSSRYQDQAVLFI 75 Query: 738 QRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTF 797 M+ G Y C + + WS PS+ LELV ++ KP P V+ G VT Sbjct: 76 PAMKRSLAGRYRC---SYQNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132 Query: 798 NCSTPHQHMSFILYKDGSEIA-SSDRSWASPGASAAHFLIISVGIGDGGNYSCRYYDFS- 855 C T + F LYK+G + W A F II+V G Y C Y FS Sbjct: 133 QCQTRYGFDQFALYKEGDPAPYKNPERW-----YRASFPIITVTAAHSGTYRC--YSFSS 185 Query: 856 ----IWSEPSDPVELVVTEFYPKPTLL--AQPGPV 884 +WS PSDP+ELVVT P+ L P PV Sbjct: 186 RDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPV 220 Score = 71.6 bits (174), Expect = 5e-12 Identities = 72/251 (28%), Positives = 103/251 (41%), Gaps = 26/251 (10%) Query: 873 PKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTV 932 PKP+L A P +V K V LRCQG G+ L++ + Q ++V + + Sbjct: 26 PKPSLQALPSSLVPLEKPVTLRCQGP-PGVDLYRLEKLSSSRYQDQAV------LFIPAM 78 Query: 933 GAEDSGNYSCIYYETTMSNRGSYLSMP---LMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989 +G Y C Y GS S+P L + T F KP L A+P V G +VTL Sbjct: 79 KRSLAGRYRCSY------QNGSLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTL 132 Query: 990 WCRGPVHGVGYILHKEGEAT---SMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTS 1046 C+ + L+KEG+ + + W S FPI ++ G Y C Sbjct: 133 QCQTRYGFDQFALYKEGDPAPYKNPERWYRAS----FPIITVTAAHSGTYRCYSFSSRDP 188 Query: 1047 SIKIQPSNTLELLVTGLLPKPSLL-AQPGPMVAPGENMTLQCQGELPDSTFV--LLKEGA 1103 + PS+ LEL+VTG PS L +P VA T + + F + Sbjct: 189 YLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSEATAELTVSFTNEVFTTETSRSIT 248 Query: 1104 QEPLEQQRPSG 1114 P E P+G Sbjct: 249 ASPKESDSPAG 259 Score = 57.4 bits (137), Expect = 9e-08 Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 208 TLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEK 267 +LWS PS+ L+LV G++ KP+L+A PGP ++ G + L+CQ FAL + D Sbjct: 94 SLWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGD--P 151 Query: 268 SFYHKKTIKNEANFFFQSLKIQDTGHYLCFYYDA--SYRGSLLSDVLKIWVTDT 319 + Y A+F ++ +G Y C+ + + Y S SD L++ VT T Sbjct: 152 APYKNPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGT 205 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.433 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,503,965 Number of Sequences: 37866 Number of extensions: 3132959 Number of successful extensions: 12611 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 86 Number of HSP's successfully gapped in prelim test: 185 Number of HSP's that attempted gapping in prelim test: 8169 Number of HSP's gapped (non-prelim): 2389 length of query: 1336 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1222 effective length of database: 13,930,794 effective search space: 17023430268 effective search space used: 17023430268 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.