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Search of human proteins with 45504376
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45504376 synaptotagmin VI [Homo sapiens]
(425 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45504376 synaptotagmin VI [Homo sapiens] 865 0.0
gi|39752671 synaptotagmin X [Homo sapiens] 604 e-173
gi|28376627 synaptotagmin IX [Homo sapiens] 531 e-151
gi|238550198 synaptotagmin III [Homo sapiens] 413 e-115
gi|238550196 synaptotagmin III [Homo sapiens] 413 e-115
gi|14150054 synaptotagmin III [Homo sapiens] 413 e-115
gi|209447073 synaptotagmin I [Homo sapiens] 298 8e-81
gi|5032139 synaptotagmin I [Homo sapiens] 298 8e-81
gi|209447070 synaptotagmin I [Homo sapiens] 298 8e-81
gi|211059429 synaptotagmin II [Homo sapiens] 295 4e-80
gi|31543670 synaptotagmin II [Homo sapiens] 295 4e-80
gi|92859638 synaptotagmin V [Homo sapiens] 292 3e-79
gi|38570146 synaptotagmin VII [Homo sapiens] 261 7e-70
gi|24308219 synaptotagmin IV [Homo sapiens] 230 2e-60
gi|216548478 synaptotagmin XI [Homo sapiens] 217 1e-56
gi|40068038 B/K protein [Homo sapiens] 189 3e-48
gi|29366828 synaptotagmin XII [Homo sapiens] 171 9e-43
gi|94536846 synaptotagmin VIII [Homo sapiens] 167 2e-41
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 167 2e-41
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 167 2e-41
gi|6005997 double C2-like domains, beta [Homo sapiens] 163 2e-40
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 162 4e-40
gi|47078261 double C2-like domains, alpha [Homo sapiens] 155 7e-38
gi|24308233 synaptotagmin XIII [Homo sapiens] 145 5e-35
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 141 1e-33
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 125 1e-28
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 125 1e-28
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 115 1e-25
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 114 2e-25
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 112 6e-25
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 865 bits (2234), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MPWRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEV 60
MPWRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEV
Sbjct: 1 MPWRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEV 60
Query: 61 QMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIG 120
QMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIG
Sbjct: 61 QMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIG 120
Query: 121 RIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSS 180
RIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSS
Sbjct: 121 RIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSS 180
Query: 181 DPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRH 240
DPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRH
Sbjct: 181 DPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRH 240
Query: 241 DMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKC 300
DMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKC
Sbjct: 241 DMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKC 300
Query: 301 RNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS 360
RNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS
Sbjct: 301 RNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS 360
Query: 361 LLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKE 420
LLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKE
Sbjct: 361 LLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKE 420
Query: 421 GNPRL 425
GNPRL
Sbjct: 421 GNPRL 425
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 604 bits (1558), Expect = e-173
Identities = 294/418 (70%), Positives = 345/418 (82%), Gaps = 6/418 (1%)
Query: 3 WRNKEASSPSSANPP-LEALQSPSFRGNMADKLKDPS--TLGFLEAAVKISHTSPDIPAE 59
W++K +S + P + + + F ++K+ + +E A+KISHTSPDIPAE
Sbjct: 84 WKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAVKAIEPAIKISHTSPDIPAE 143
Query: 60 VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPA---AEQP 116
VQ ++KEH+++H R+QRQ TEP SSTRH+SF+RHLPRQM VSSVD+ P E
Sbjct: 144 VQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETT 203
Query: 117 TSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDF 176
TSIGRIKPELYKQKSVD E ++E K CGK+NF+L+YDYE E L+V+I+KA DLPAKDF
Sbjct: 204 TSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDF 263
Query: 177 CGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDR 236
G+SDPYVK+YLLPDRK K QTRVHRKTLNP FDE F FPV Y++L++RKLH SV+DFDR
Sbjct: 264 TGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDR 323
Query: 237 FSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLT 296
FSRHDMIGEVILDNLFE SDLSRE ++WKDI AT+ES+DLGEIMFSLCYLPTAGR+TLT
Sbjct: 324 FSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLT 383
Query: 297 VIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENM 356
VIKCRNLKAMDITG SDPYVKVSL+C+GRRLKK+KTT KKNTLNPVYNEAIIFDIPPEN+
Sbjct: 384 VIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENV 443
Query: 357 DQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEV 414
DQVSL I+VMDYDRVGHNE+IGVCR G+ AEGLGRDHWNEMLAY RKPI HWH L+E+
Sbjct: 444 DQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLEL 501
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 531 bits (1369), Expect = e-151
Identities = 258/415 (62%), Positives = 322/415 (77%), Gaps = 7/415 (1%)
Query: 1 MPWRNKEASSPSSAN--PPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPA 58
+PWR + S S N PL + + + ++ DP T ++++KISHTSPDIP
Sbjct: 80 VPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT-PCPDSSMKISHTSPDIPL 138
Query: 59 EVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTS 118
Q ++E+ R+QRQ TEP SS RH S +R Q+++S+ D+ + EQ T
Sbjct: 139 STQTGIQENCAHGVRVQRQVTEPTSSARHNSIRR----QLNLSNPDFNIQQLQKQEQLTG 194
Query: 119 IGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCG 178
IGRIKPELYKQ+S+D +D + +K+CGK+NF L+YD + E LIV+I KA +LPAKDF G
Sbjct: 195 IGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSG 254
Query: 179 SSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFS 238
+SDPYVKIYLLPDRK K QT+VHRKTLNP FDE F FPVPY +L RKLH SV+DFDRFS
Sbjct: 255 TSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFS 314
Query: 239 RHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVI 298
RHD+IG+V++D+ + +D RE +WKDI+Y T+++VDLGE+MFSLCYLPTAGRLT+T+I
Sbjct: 315 RHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITII 374
Query: 299 KCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQ 358
K RNLKAMDITG SDPYVKVSL+CDGRRLKK+KT+ K+NTLNPVYNEAI+FD+PPEN+DQ
Sbjct: 375 KARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQ 434
Query: 359 VSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVE 413
+ L I+VMDYDRVGHNEIIGVC+VG AE LGRDHW+EML+YPRKPIAHWHSLVE
Sbjct: 435 IHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 413 bits (1062), Expect = e-115
Identities = 227/447 (50%), Positives = 292/447 (65%), Gaps = 38/447 (8%)
Query: 15 NPPLEALQSPSFRGNMADKLKDPSTLGF----------LEAAVKISHTSPDIPAE----- 59
+PP L P G +PS L + A VK S TSP++P+E
Sbjct: 139 HPPFAELLEPGSLGG--SDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGS 196
Query: 60 --VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNE--------- 108
+ + + + +Q T A +TR+ + R L +Q S D +E
Sbjct: 197 GLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLP 256
Query: 109 LPPAAEQPTSIGRIKPELYK------QKSVDGEDAKSEATKS-CGKINFSLRYDYETETL 161
LP E+ IG+IKPELY+ ++S G + T + CG+I+F+LRY Y ++ L
Sbjct: 257 LPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
Query: 162 IVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEE 221
+VRIL+A DLPAKD G SDPYVKIYLLPDRK K QT+VHRKTLNP F+E F F VP E
Sbjct: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAE 376
Query: 222 LADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIM 281
LA RKLH SV+DFDRFSRHD+IG+V+LDNL E ++ + +W+DI SE DLGE+
Sbjct: 377 LAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELN 436
Query: 282 FSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNP 341
FSLCYLPTAGRLT+T+IK NLKAMD+TG+SDPYVK SL+ +GRRLKK+KT+IKKNTLNP
Sbjct: 437 FSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP 496
Query: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVG-ITAEGLGRDHWNEMLAY 400
YNEA++FD+ PE+++ V L I+V+DYD +GHNE+IGVCRVG A+ GR+HW EMLA
Sbjct: 497 TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLAN 556
Query: 401 PRKPIAHWHSLVEVK--KSFKEGNPRL 425
PRKP+ HWH LVE K SF +G+ L
Sbjct: 557 PRKPVEHWHQLVEEKTVTSFTKGSKGL 583
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 413 bits (1062), Expect = e-115
Identities = 227/447 (50%), Positives = 292/447 (65%), Gaps = 38/447 (8%)
Query: 15 NPPLEALQSPSFRGNMADKLKDPSTLGF----------LEAAVKISHTSPDIPAE----- 59
+PP L P G +PS L + A VK S TSP++P+E
Sbjct: 139 HPPFAELLEPGSLGG--SDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGS 196
Query: 60 --VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNE--------- 108
+ + + + +Q T A +TR+ + R L +Q S D +E
Sbjct: 197 GLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLP 256
Query: 109 LPPAAEQPTSIGRIKPELYK------QKSVDGEDAKSEATKS-CGKINFSLRYDYETETL 161
LP E+ IG+IKPELY+ ++S G + T + CG+I+F+LRY Y ++ L
Sbjct: 257 LPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
Query: 162 IVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEE 221
+VRIL+A DLPAKD G SDPYVKIYLLPDRK K QT+VHRKTLNP F+E F F VP E
Sbjct: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAE 376
Query: 222 LADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIM 281
LA RKLH SV+DFDRFSRHD+IG+V+LDNL E ++ + +W+DI SE DLGE+
Sbjct: 377 LAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELN 436
Query: 282 FSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNP 341
FSLCYLPTAGRLT+T+IK NLKAMD+TG+SDPYVK SL+ +GRRLKK+KT+IKKNTLNP
Sbjct: 437 FSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP 496
Query: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVG-ITAEGLGRDHWNEMLAY 400
YNEA++FD+ PE+++ V L I+V+DYD +GHNE+IGVCRVG A+ GR+HW EMLA
Sbjct: 497 TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLAN 556
Query: 401 PRKPIAHWHSLVEVK--KSFKEGNPRL 425
PRKP+ HWH LVE K SF +G+ L
Sbjct: 557 PRKPVEHWHQLVEEKTVTSFTKGSKGL 583
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 413 bits (1062), Expect = e-115
Identities = 227/447 (50%), Positives = 292/447 (65%), Gaps = 38/447 (8%)
Query: 15 NPPLEALQSPSFRGNMADKLKDPSTLGF----------LEAAVKISHTSPDIPAE----- 59
+PP L P G +PS L + A VK S TSP++P+E
Sbjct: 139 HPPFAELLEPGSLGG--SDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGS 196
Query: 60 --VQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNE--------- 108
+ + + + +Q T A +TR+ + R L +Q S D +E
Sbjct: 197 GLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLP 256
Query: 109 LPPAAEQPTSIGRIKPELYK------QKSVDGEDAKSEATKS-CGKINFSLRYDYETETL 161
LP E+ IG+IKPELY+ ++S G + T + CG+I+F+LRY Y ++ L
Sbjct: 257 LPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
Query: 162 IVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEE 221
+VRIL+A DLPAKD G SDPYVKIYLLPDRK K QT+VHRKTLNP F+E F F VP E
Sbjct: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAE 376
Query: 222 LADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIM 281
LA RKLH SV+DFDRFSRHD+IG+V+LDNL E ++ + +W+DI SE DLGE+
Sbjct: 377 LAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELN 436
Query: 282 FSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNP 341
FSLCYLPTAGRLT+T+IK NLKAMD+TG+SDPYVK SL+ +GRRLKK+KT+IKKNTLNP
Sbjct: 437 FSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNP 496
Query: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVG-ITAEGLGRDHWNEMLAY 400
YNEA++FD+ PE+++ V L I+V+DYD +GHNE+IGVCRVG A+ GR+HW EMLA
Sbjct: 497 TYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLAN 556
Query: 401 PRKPIAHWHSLVEVK--KSFKEGNPRL 425
PRKP+ HWH LVE K SF +G+ L
Sbjct: 557 PRKPVEHWHQLVEEKTVTSFTKGSKGL 583
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 298 bits (762), Expect = 8e-81
Identities = 142/281 (50%), Positives = 202/281 (71%), Gaps = 4/281 (1%)
Query: 133 DGEDAKS-EATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD 191
DGE+ + + + GK+ +SL YD++ L+V I++A +LPA D G+SDPYVK++LLPD
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 192 RKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251
+K K +T+VHRKTLNP F+E F F VPY EL + L ++V+DFDRFS+HD+IGE +
Sbjct: 190 KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP-- 247
Query: 252 FEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITG 310
D T W+D+Q A E + LG+I FSL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG 307
Query: 311 YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDR 370
SDPYVK+ L+ +G+RLKKKKTTIKKNTLNP YNE+ F++P E + +V ++++V+DYD+
Sbjct: 308 LSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDK 367
Query: 371 VGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+G N+ IG VG + G HW++MLA PR+PIA WH+L
Sbjct: 368 IGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 298 bits (762), Expect = 8e-81
Identities = 142/281 (50%), Positives = 202/281 (71%), Gaps = 4/281 (1%)
Query: 133 DGEDAKS-EATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD 191
DGE+ + + + GK+ +SL YD++ L+V I++A +LPA D G+SDPYVK++LLPD
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 192 RKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251
+K K +T+VHRKTLNP F+E F F VPY EL + L ++V+DFDRFS+HD+IGE +
Sbjct: 190 KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP-- 247
Query: 252 FEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITG 310
D T W+D+Q A E + LG+I FSL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG 307
Query: 311 YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDR 370
SDPYVK+ L+ +G+RLKKKKTTIKKNTLNP YNE+ F++P E + +V ++++V+DYD+
Sbjct: 308 LSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDK 367
Query: 371 VGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+G N+ IG VG + G HW++MLA PR+PIA WH+L
Sbjct: 368 IGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 298 bits (762), Expect = 8e-81
Identities = 142/281 (50%), Positives = 202/281 (71%), Gaps = 4/281 (1%)
Query: 133 DGEDAKS-EATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD 191
DGE+ + + + GK+ +SL YD++ L+V I++A +LPA D G+SDPYVK++LLPD
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 192 RKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251
+K K +T+VHRKTLNP F+E F F VPY EL + L ++V+DFDRFS+HD+IGE +
Sbjct: 190 KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP-- 247
Query: 252 FEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITG 310
D T W+D+Q A E + LG+I FSL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG 307
Query: 311 YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDR 370
SDPYVK+ L+ +G+RLKKKKTTIKKNTLNP YNE+ F++P E + +V ++++V+DYD+
Sbjct: 308 LSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDK 367
Query: 371 VGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+G N+ IG VG + G HW++MLA PR+PIA WH+L
Sbjct: 368 IGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 295 bits (756), Expect = 4e-80
Identities = 141/280 (50%), Positives = 201/280 (71%), Gaps = 3/280 (1%)
Query: 133 DGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192
+GE + + ++ GK+ FSL YD++ L V +L+A +LPA D G+SDPYVK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 193 KCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLF 252
K K +T+VHRKTLNP F+E F F VPY+EL + L ++++DFDRFS+HD+IGEV +
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
Query: 253 EASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311
DL + W+D+Q E + LG+I SL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371
SDPYVK+ L+ +G+RLKKKKTT+KK TLNP +NE+ F+IP E + +V ++++V+DYD++
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
G NE IG VG A G HW++MLA PR+PIA WHSL
Sbjct: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 295 bits (756), Expect = 4e-80
Identities = 141/280 (50%), Positives = 201/280 (71%), Gaps = 3/280 (1%)
Query: 133 DGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192
+GE + + ++ GK+ FSL YD++ L V +L+A +LPA D G+SDPYVK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 193 KCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLF 252
K K +T+VHRKTLNP F+E F F VPY+EL + L ++++DFDRFS+HD+IGEV +
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
Query: 253 EASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311
DL + W+D+Q E + LG+I SL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371
SDPYVK+ L+ +G+RLKKKKTT+KK TLNP +NE+ F+IP E + +V ++++V+DYD++
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
G NE IG VG A G HW++MLA PR+PIA WHSL
Sbjct: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 292 bits (748), Expect = 3e-79
Identities = 154/331 (46%), Positives = 216/331 (65%), Gaps = 12/331 (3%)
Query: 83 SSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEAT 142
S R T K Q+H+ V + + I +++PE+ + + + A
Sbjct: 54 SCRRRTGKKSQAQAQVHLQEVKGLGQ--------SYIDKVQPEVEELEPAPSGPGQQVAD 105
Query: 143 K-SCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVH 201
K G++ +SL YD+++ L+V IL+A L A D GSSDPYV++YLLPD++ + +T+VH
Sbjct: 106 KHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVH 165
Query: 202 RKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRET 261
R+TLNP F E F F VPY EL R L ++V+DFDRFSR+D IGEV + + DL R
Sbjct: 166 RQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVP--MSSVDLGRPV 223
Query: 262 SIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSL 320
W+++Q A E + LG+I FSL Y+PTAG+LT+ V++ +NLK MD+ G SDPYVKV L
Sbjct: 224 QAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHL 283
Query: 321 LCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVC 380
L G++++KKKTTIKKNTLNP YNEA F++P + + +V + ++V+DYD++G NE IG
Sbjct: 284 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV 343
Query: 381 RVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
VG A G G HW +MLA PR+PIA WHSL
Sbjct: 344 AVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 261 bits (668), Expect = 7e-70
Identities = 131/280 (46%), Positives = 189/280 (67%), Gaps = 8/280 (2%)
Query: 138 KSEATKSC-----GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192
+ EA + C G+I FS+ Y+++ TL V+I+KA +LPAKDF G+SDP+VKIYLLPD+
Sbjct: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183
Query: 193 KCKLQTRVHRKTLNPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251
K KL+T+V RK LNP ++E F F PYE++ R L+L V D+DRFSR+D IGEV +
Sbjct: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIP-- 241
Query: 252 FEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311
DL++ + WKD++ + S GE++ SLCY P+A + + +IK RNLKAMDI G
Sbjct: 242 LNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGT 301
Query: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371
SDPYVKV L+ +R++KKKT K LNP++NE+ FDIP E + + +++I+VMD D++
Sbjct: 302 SDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKL 361
Query: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
N++IG + + HW +M+A PR+P+A WH L
Sbjct: 362 SRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 401
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 230 bits (587), Expect = 2e-60
Identities = 127/314 (40%), Positives = 190/314 (60%), Gaps = 20/314 (6%)
Query: 116 PTSIGRIKPELY---KQKSVDGEDAKS-------EATKSCGKINFSLRYDYETETLIVRI 165
P+ + P+L+ +++SV E KS E + G + FSL Y++E + +V I
Sbjct: 115 PSDLENATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNI 174
Query: 166 LKAFDLPAKDFCG-SSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF-PVPYEELA 223
+A LPA D +SDPY+K+ +LP++K K++TRV RKTL+P FDE F F +PY ++
Sbjct: 175 KEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQ 234
Query: 224 DRKLHLSVFDFDRFSRHDMIGEVILD----NLFEASDLSRETSIWKDIQYATSESVDLGE 279
+ LH ++ FDRFSR D+IGEV++ L E L I ++++ ++ GE
Sbjct: 235 ELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR----GE 290
Query: 280 IMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTL 339
++ SLCY T LT+ V+K R+L D++G SDPYVKV+L +R+ KKKT +KK T
Sbjct: 291 LLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTP 350
Query: 340 NPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLA 399
N V+NE +FDIP E ++ +S+ V+D +R NE+IG +G AEG G +HW E+
Sbjct: 351 NAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICD 410
Query: 400 YPRKPIAHWHSLVE 413
YPR+ IA WH L +
Sbjct: 411 YPRRQIAKWHVLCD 424
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 217 bits (553), Expect = 1e-56
Identities = 127/316 (40%), Positives = 187/316 (59%), Gaps = 16/316 (5%)
Query: 103 VDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLI 162
+DYG EL + I + P K S + E G + FS+ Y++ + L+
Sbjct: 126 MDYGEELR------SPITSLTPGESKTTS----PSSPEEDVMLGSLTFSVDYNFPKKALV 175
Query: 163 VRILKAFDLPAKDF-CGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF-PVPYE 220
V I +A LP D SDPY+K+ +LPD++ +++TRV RKTL+P FDE F F +PY
Sbjct: 176 VTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYS 235
Query: 221 ELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDI-QYATSESVDLGE 279
+L D LH V FDRFSR D+IGEV++ L + + + +DI + + + GE
Sbjct: 236 QLQDLVLHFLVLSFDRFSRDDVIGEVMVP-LAGVDPSTGKVQLTRDIIKRNIQKCISRGE 294
Query: 280 IMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYS-DPYVKVSLLCDGRRLKKKKTTIKKNT 338
+ SL Y P A R+T+ V+K R+L MDITG S +PYVKV++ +R+ KKKT +KK T
Sbjct: 295 LQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCT 354
Query: 339 LNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGI-TAEGLGRDHWNEM 397
LNP++NE+ I+DIP + + +S+ V+D+DR NE++G +G + G +HW E+
Sbjct: 355 LNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREV 414
Query: 398 LAYPRKPIAHWHSLVE 413
PRKP+A WHSL E
Sbjct: 415 CESPRKPVAKWHSLSE 430
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 189 bits (481), Expect = 3e-48
Identities = 112/304 (36%), Positives = 171/304 (56%), Gaps = 15/304 (4%)
Query: 121 RIKPELYKQKSVDGE-----DAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLP--- 172
+ +P LY S + D + + G ++FS +YD L VR+++A DLP
Sbjct: 156 KFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPI 215
Query: 173 ----AKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLH 228
++ S+PYVKI LLPD+K QT V RKT P F+E + F +P+ E R L
Sbjct: 216 SHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLL 275
Query: 229 LSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLP 288
L+V DFD+FSRH +IG+V + L E DL + WK + ++ V+LGE++ SL YLP
Sbjct: 276 LTVVDFDKFSRHCVIGKVSVP-LCEV-DLVKGGHWWKALIPSSQNEVELGELLLSLNYLP 333
Query: 289 TAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAII 348
+AGRL + VI+ + L D++ SDP+VK+ L+ + +K KKT+ + T++P YNE+
Sbjct: 334 SAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFS 393
Query: 349 FDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAYPRKPIAH 407
F +P E ++ SL+ +V ++ N+ IG +G + G +HW ML R +
Sbjct: 394 FKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQ 453
Query: 408 WHSL 411
WHSL
Sbjct: 454 WHSL 457
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 171 bits (434), Expect = 9e-43
Identities = 100/293 (34%), Positives = 161/293 (54%), Gaps = 9/293 (3%)
Query: 126 LYKQKSVDGEDAKSEATKS------CGKINFSLRYDYETETLIVRILKAFDLPAKDFCGS 179
L K +S D ++ S + + G++ S+ YD + TL V +++ DL ++
Sbjct: 128 LRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASF 187
Query: 180 SDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSR 239
++++ LLPD + +R+ R + FDE F P+ L ++ L SVF D R
Sbjct: 188 ESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDER 247
Query: 240 HDMIGEVILDNLFEASDLSRET-SIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVI 298
+ G V L DL + S W +Q + +GEI+ SL YLPTA RLT+ V+
Sbjct: 248 NVSTGVVELK--LSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVV 305
Query: 299 KCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQ 358
K +NL + +DP+VKV LL DGR++ KKKT +K++ NPV+NEA+IF +P +
Sbjct: 306 KAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQD 365
Query: 359 VSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+SL ++V + G + +G +G +A G+G HWN+MLA R+P++ WH++
Sbjct: 366 LSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 167 bits (423), Expect = 2e-41
Identities = 99/284 (34%), Positives = 154/284 (54%), Gaps = 10/284 (3%)
Query: 129 QKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYL 188
Q VDG ++ + G++ SL +D+ ++ + V + +A DL G+ DPY ++ +
Sbjct: 102 QPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRPG---GTVDPYARVSV 158
Query: 189 LPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVIL 248
+ +T+VHR TL P FDE F +P EL L + +F+F RFS H+ +GE+ L
Sbjct: 159 STQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRL 218
Query: 249 DNLFEASDLSRETSIWKDI-QYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMD 307
DL W + A ++ +GE+ FSL Y+P++GRLT+ V++ R L+
Sbjct: 219 P--LGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRP-- 274
Query: 308 ITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMD 367
G ++PYVKV L+ + R+ KK+KT KK T P +NEA F +P + V L+++V D
Sbjct: 275 --GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWD 332
Query: 368 YDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
E +G +G A G HW +MLA+ R+PIA H L
Sbjct: 333 RSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPL 376
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 167 bits (422), Expect = 2e-41
Identities = 112/326 (34%), Positives = 172/326 (52%), Gaps = 28/326 (8%)
Query: 112 AAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDL 171
AA QP + + P +++ + D+ EAT + G + FSL YD + +L I+KA L
Sbjct: 362 AAPQPAAARQPPPPEEEEEEANSYDS-DEAT-TLGALEFSLLYDQDNSSLQCTIIKAKGL 419
Query: 172 PAKDFCGSSDPYVKIYLLP--DRKCKLQTRVHRKTLNPTFDENF-HFPVPYEELADRKLH 228
D G +DPYVK++LLP + KL+T+ R T NP ++E + + E++ + L
Sbjct: 420 KPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLR 479
Query: 229 LSVFDFDRFSRHDMIGE-----------------VILDNLFE-----ASDLSRETSIWKD 266
+SV D D+F ++ IGE + L+ + + +R +++++
Sbjct: 480 ISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEE 539
Query: 267 IQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGR 325
Q ++ G+I+ SL Y G L + +I+C +L AMD GYSDP+VK+ L D
Sbjct: 540 EQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMG 599
Query: 326 RLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGIT 385
+ K KT IKK TLNP +NE +DI ++ + SL ISV DYD N+ IG C++GI+
Sbjct: 600 KKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGIS 659
Query: 386 AEGLGRDHWNEMLAYPRKPIAHWHSL 411
A+G HW E L K I WH L
Sbjct: 660 AKGERLKHWYECLKNKDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 167 bits (422), Expect = 2e-41
Identities = 112/326 (34%), Positives = 172/326 (52%), Gaps = 28/326 (8%)
Query: 112 AAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDL 171
AA QP + + P +++ + D+ EAT + G + FSL YD + +L I+KA L
Sbjct: 358 AAPQPAAARQPPPPEEEEEEANSYDS-DEAT-TLGALEFSLLYDQDNSSLQCTIIKAKGL 415
Query: 172 PAKDFCGSSDPYVKIYLLP--DRKCKLQTRVHRKTLNPTFDENF-HFPVPYEELADRKLH 228
D G +DPYVK++LLP + KL+T+ R T NP ++E + + E++ + L
Sbjct: 416 KPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLR 475
Query: 229 LSVFDFDRFSRHDMIGE-----------------VILDNLFE-----ASDLSRETSIWKD 266
+SV D D+F ++ IGE + L+ + + +R +++++
Sbjct: 476 ISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEE 535
Query: 267 IQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGR 325
Q ++ G+I+ SL Y G L + +I+C +L AMD GYSDP+VK+ L D
Sbjct: 536 EQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMG 595
Query: 326 RLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGIT 385
+ K KT IKK TLNP +NE +DI ++ + SL ISV DYD N+ IG C++GI+
Sbjct: 596 KKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGIS 655
Query: 386 AEGLGRDHWNEMLAYPRKPIAHWHSL 411
A+G HW E L K I WH L
Sbjct: 656 AKGERLKHWYECLKNKDKKIERWHQL 681
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 163 bits (413), Expect = 2e-40
Identities = 104/287 (36%), Positives = 153/287 (53%), Gaps = 8/287 (2%)
Query: 133 DGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLP-- 190
D + +S+ + G ++FSL YD E L I KA L D G +DPYVK++LLP
Sbjct: 115 DADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGA 174
Query: 191 DRKCKLQTRVHRKTLNPTFDENF-HFPVPYEELADRKLHLSVFDFDRFSRHDMIGE--VI 247
+ KL+T+ R TLNPT++E ++ + E++ + L +SV D D+F ++ IGE V
Sbjct: 175 SKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVP 234
Query: 248 LDNLFEASDLSRETSIWKDIQYATSESVDL---GEIMFSLCYLPTAGRLTLTVIKCRNLK 304
L L + + K + +E L G I+ SL Y L + +++C +L
Sbjct: 235 LKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLA 294
Query: 305 AMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLIS 364
AMD GYSDPYVK L D + K KT +KK TLNP +NE ++I ++ + SL ++
Sbjct: 295 AMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVT 354
Query: 365 VMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
V DYD N+ IG +GI A+G HW + L K I WH+L
Sbjct: 355 VWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401
Score = 88.2 bits (217), Expect = 1e-17
Identities = 52/125 (41%), Positives = 76/125 (60%), Gaps = 4/125 (3%)
Query: 126 LYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVK 185
L KQ VD + KS + G+I SL+Y + + L+V I++ L A D G SDPYVK
Sbjct: 250 LEKQLPVDKTEDKSLEER--GRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVK 307
Query: 186 IYLLP--DRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMI 243
YL P D+K K +T V +KTLNP F+E F + + + +LA + L ++V+D+D +D I
Sbjct: 308 TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFI 367
Query: 244 GEVIL 248
G V+L
Sbjct: 368 GGVVL 372
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 162 bits (411), Expect = 4e-40
Identities = 101/299 (33%), Positives = 163/299 (54%), Gaps = 13/299 (4%)
Query: 119 IGRIKPELYKQKSVDGEDAKSEATKSC-GKINFSLRYDYETETLIVRILKAFDLPAKDFC 177
+G I PELYK + ++++ C G++ FS+ Y+ E E L+V ++KA L A
Sbjct: 124 VGAINPELYKFPE---DKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS-- 178
Query: 178 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 237
+ P VK+YLLPD + LQ++ RKT NP FDE+F F V + + R L SV+ DR
Sbjct: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
Query: 238 SRHDMIGEVI--LDNLFEASDLSRETSIWKDIQYATSE-SVDLGEIMFSLCYLPTAGRLT 294
+H ++G+V+ L N D R IW+D++ + E + G++ F L Y RLT
Sbjct: 239 RKHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
Query: 295 LTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPE 354
+ V++ + L+ + G +VKVSL+ + +K KKT+ ++NPVYNE F
Sbjct: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
Query: 355 NMDQVSLLISVMDYDRVGHNEIIGVCRVG--ITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+D SL ++V+ ++ +G VG + G +HW+EML+ P++ + WH+L
Sbjct: 357 ELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 155 bits (392), Expect = 7e-38
Identities = 107/332 (32%), Positives = 162/332 (48%), Gaps = 38/332 (11%)
Query: 110 PPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAF 169
PPAA +G PE VD D S+ + G + F L YD + TL IL+A
Sbjct: 63 PPAA----LLGATTPE--DGAEVDSYD--SDDATALGTLEFDLLYDRASCTLHCSILRAK 114
Query: 170 DLPAKDFCGSSDPYVKIYLLPD--RKCKLQTRVHRKTLNPTFDENFHFP-VPYEELADRK 226
L DF G +DPYVK++LLP + KL+T+ R TLNP ++E+ + + +++ +
Sbjct: 115 GLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKV 174
Query: 227 LHLSVFDFDRFSRHDMIGE--VILDNLFEASDLSRETSIWKDIQYATSESV--------- 275
L ++V D D+ S ++ IGE V L L + + + + A+ S+
Sbjct: 175 LRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISC 234
Query: 276 ----------------DLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVS 319
+ G I+ SL Y L + +++C +L AMD+ GYSDPYVK
Sbjct: 235 YLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTY 294
Query: 320 LLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGV 379
L D + K KT +KK TLNP +NE ++I + +L ++V DYD N+ IG
Sbjct: 295 LRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGG 354
Query: 380 CRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
+G A G R HW++ L P + WH+L
Sbjct: 355 VSLGPGARGEARKHWSDCLQQPDAALERWHTL 386
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 145 bits (367), Expect = 5e-35
Identities = 97/320 (30%), Positives = 166/320 (51%), Gaps = 25/320 (7%)
Query: 111 PAAEQPTSIGRIKPELYKQKSVDGEDA--------------KSEATKSCGKINFSLRYDY 156
PA+ QP + R+K ++ ++ + ++ K+ + K+++ L YD
Sbjct: 111 PASPQPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLDYDC 170
Query: 157 ETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR-KCKLQTRVHRKTLNPTFDENFHF 215
+ L V L+A + G D YV+ + + QT + ++ L+ T++E
Sbjct: 171 QKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVL 227
Query: 216 PVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSE-S 274
P+ EEL L L++ DRFSRH + GE+ L + + + + W +++ + E S
Sbjct: 228 PLAEEELPTATLTLTLRTCDRFSRHSVAGELRLG--LDGTSVPLGAAQWGELKTSAKEPS 285
Query: 275 VDLGEIMFSLCYLPTAGRLTLTVIKCRNL---KAMDITGYSDPYVKVSLLCDGRRLKKKK 331
GE++ S+ YLP A RL + +IK +NL ++ ++ G D VKV+L R+LKKK+
Sbjct: 286 AGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLG-KDVSVKVTLKHQARKLKKKQ 344
Query: 332 TTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGR 391
T K+ +NPV+NE I+F++P + + S+ + V+ D G + +G C +G+ G R
Sbjct: 345 TKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSGSER 404
Query: 392 DHWNEMLAYPRKPIAHWHSL 411
HW EML PR+ IA WH L
Sbjct: 405 SHWEEMLKNPRRQIAMWHQL 424
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 141 bits (356), Expect = 1e-33
Identities = 88/252 (34%), Positives = 139/252 (55%), Gaps = 11/252 (4%)
Query: 119 IGRIKPELYKQKSVDGEDAKSEATKSC-GKINFSLRYDYETETLIVRILKAFDLPAKDFC 177
+G I PELYK + ++++ C G++ FS+ Y+ E E L+V ++KA L A
Sbjct: 124 VGAINPELYKFPE---DKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS-- 178
Query: 178 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 237
+ P VK+YLLPD + LQ++ RKT NP FDE+F F V + + R L SV+ DR
Sbjct: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
Query: 238 SRHDMIGEVI--LDNLFEASDLSRETSIWKDIQYATSE-SVDLGEIMFSLCYLPTAGRLT 294
+H ++G+V+ L N D R IW+D++ + E + G++ F L Y RLT
Sbjct: 239 RKHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
Query: 295 LTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPE 354
+ V++ + L+ + G +VKVSL+ + +K KKT+ ++NPVYNE F
Sbjct: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
Query: 355 NMDQVSLLISVM 366
+D SL ++V+
Sbjct: 357 ELDTASLSLTVV 368
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 125 bits (313), Expect = 1e-28
Identities = 88/304 (28%), Positives = 150/304 (49%), Gaps = 25/304 (8%)
Query: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPD--RKCKLQTRVHR 202
G+I FSL+Y+ +T++L+V + + L D S+PYVK YLLPD R+ K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIG--EVILDNLFEASDLSRE 260
T+NP +DE + +P LA R L SV+ RF R+ +G E+ +D+ L
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 TSIWKDI--QYATSESVDLGEIMFSLCYLPTA----------------GRLTLTVIKCRN 302
+ I + T GE++ SL Y+P + G L + + + +N
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 303 LKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSL 361
L A G SD +VK LL + K+KT + K TLNP YN +++ + E++ + L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 362 LISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEG 421
++V D + + N+ +G R+G+ G+ + + + ++ W + + S+ EG
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGV-GTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEG 656
Query: 422 NPRL 425
+L
Sbjct: 657 TLQL 660
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 125 bits (313), Expect = 1e-28
Identities = 88/304 (28%), Positives = 150/304 (49%), Gaps = 25/304 (8%)
Query: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPD--RKCKLQTRVHR 202
G+I FSL+Y+ +T++L+V + + L D S+PYVK YLLPD R+ K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 203 KTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIG--EVILDNLFEASDLSRE 260
T+NP +DE + +P LA R L SV+ RF R+ +G E+ +D+ L
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 TSIWKDI--QYATSESVDLGEIMFSLCYLPTA----------------GRLTLTVIKCRN 302
+ I + T GE++ SL Y+P + G L + + + +N
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 303 LKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSL 361
L A G SD +VK LL + K+KT + K TLNP YN +++ + E++ + L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 362 LISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEG 421
++V D + + N+ +G R+G+ G+ + + + ++ W + + S+ EG
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGV-GTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEG 656
Query: 422 NPRL 425
+L
Sbjct: 657 TLQL 660
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 115 bits (287), Expect = 1e-25
Identities = 116/462 (25%), Positives = 210/462 (45%), Gaps = 52/462 (11%)
Query: 3 WRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAV-----KISHTSPDIP 57
WRN +SS +P L+ L+ + R + L+D S+ +A V ++ ++ D
Sbjct: 804 WRNP-SSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDDE 862
Query: 58 AEVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGN--ELPPAAEQ 115
Q V + R+ T+P + H + + + + D + E A+E
Sbjct: 863 KPDQKPVTNECV--PRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASES 920
Query: 116 PTSIGRIKPE---LYKQKSVDGEDAKSEATKSC--------------GKINFSLRYDYET 158
+ R K L S G + S + S G I F++ Y
Sbjct: 921 SYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESL 980
Query: 159 ETLIVRILKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHRKTLNPTFDENFHF 215
+ L V + + DL A D SDPYVK YLLPD+ K +T V +KTLNP ++E +
Sbjct: 981 KELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRY 1040
Query: 216 PVPYEELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWKDIQYATS-- 272
+ + L +KL+LS++ D F R+ +GEV LD ++ + + W ++ T+
Sbjct: 1041 KIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPV 1100
Query: 273 --ESVDLGEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLL 321
E+ + GE+ +L Y LPT G + + V +C +L + + + +VK ++L
Sbjct: 1101 ALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 1159
Query: 322 CDGRRLKKKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMDYDRVGHNEIIGVC 380
D R ++KT T NP++N +++D PE++ + + ++V D+ ++ N+ +G
Sbjct: 1160 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 1218
Query: 381 RVGITAEGLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420
R+G G G+ + E+ + + +A W +V ++ E
Sbjct: 1219 RIGF---GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 1257
>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
Length = 1256
Score = 114 bits (285), Expect = 2e-25
Identities = 117/455 (25%), Positives = 207/455 (45%), Gaps = 54/455 (11%)
Query: 3 WRNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQM 62
WRN +SS +P L+ L+ + R + L+D S+ +A V + P E+
Sbjct: 804 WRNP-SSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVD------NQPEELVR 856
Query: 63 SVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRI 122
S ++ T+ + P R + +P + S D E A+E + R
Sbjct: 857 SAEDVSTVPTQPDNPFSHPDKLKR---MSKSVPAFLQDESDD--RETDTASESSYQLSRH 911
Query: 123 KPE---LYKQKSVDGEDAKSEATKSC--------------GKINFSLRYDYETETLIVRI 165
K L S G + S + S G I F++ Y + L V +
Sbjct: 912 KKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFV 971
Query: 166 LKAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHRKTLNPTFDENFHFPVPYEEL 222
+ DL A D SDPYVK YLLPD+ K +T V +KTLNP ++E + + + L
Sbjct: 972 AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 1031
Query: 223 ADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWKDIQYATS----ESVDL 277
+KL+LS++ D F R+ +GEV LD ++ + + W ++ T+ E+ +
Sbjct: 1032 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENR 1091
Query: 278 GEIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK 328
GE+ +L Y LPT G + + V +C +L + + + +VK ++L D R
Sbjct: 1092 GEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKS 1150
Query: 329 KKKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAE 387
++KT T NP++N +++D PE++ + + ++V D+ ++ N+ +G R+G
Sbjct: 1151 RQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGF--- 1206
Query: 388 GLGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420
G G+ + E+ + + +A W +V ++ E
Sbjct: 1207 GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 1241
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 112 bits (280), Expect = 6e-25
Identities = 114/454 (25%), Positives = 206/454 (45%), Gaps = 53/454 (11%)
Query: 4 RNKEASSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMS 63
R+++ S +P L+ L+ + R + L+D S+ +A V + P E+ S
Sbjct: 483 RDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVD------NQPEELVRS 536
Query: 64 VKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIK 123
++ T+ + P R + +P + S D E A+E + R K
Sbjct: 537 AEDVSTVPTQPDNPFSHPDKLKR---MSKSVPAFLQDESDD--RETDTASESSYQLSRHK 591
Query: 124 PE---LYKQKSVDGEDAKSEATKSC--------------GKINFSLRYDYETETLIVRIL 166
L S G + S + S G I F++ Y + L V +
Sbjct: 592 KSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVA 651
Query: 167 KAFDLPAKDFCGS-SDPYVKIYLLPDR--KCKLQTRVHRKTLNPTFDENFHFPVPYEELA 223
+ DL A D SDPYVK YLLPD+ K +T V +KTLNP ++E + + + L
Sbjct: 652 QCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILK 711
Query: 224 DRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWKDIQYATS----ESVDLG 278
+KL+LS++ D F R+ +GEV LD ++ + + W ++ T+ E+ + G
Sbjct: 712 TQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRG 771
Query: 279 EIMFSLCY---------LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKK 329
E+ +L Y LPT G + + V +C +L + + + +VK ++L D R +
Sbjct: 772 EMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSR 830
Query: 330 KKTTIKKNTLNPVYNEAIIFD-IPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEG 388
+KT T NP++N +++D PE++ + + ++V D+ ++ N+ +G R+G G
Sbjct: 831 QKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGF---G 886
Query: 389 LGRDHWNEM--LAYPRKPIAHWHSLVEVKKSFKE 420
G+ + E+ + + +A W +V ++ E
Sbjct: 887 TGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIE 920
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,606,170
Number of Sequences: 37866
Number of extensions: 722072
Number of successful extensions: 2686
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 1828
Number of HSP's gapped (non-prelim): 555
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.