Search of human proteins with 45439335

Search of human proteins with 45439335

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45439335 porcupine isoform D [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45439335 porcupine isoform D [Homo sapiens]                        944   0.0  
gi|45439331 porcupine isoform B [Homo sapiens]                        929   0.0  
gi|45439333 porcupine isoform C [Homo sapiens]                        925   0.0  
gi|45439329 porcupine isoform A [Homo sapiens]                        914   0.0  
gi|45439337 porcupine isoform E [Homo sapiens]                        767   0.0  
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    55   1e-07
gi|122937404 membrane bound O-acyltransferase domain containing ...    55   1e-07
gi|40548387 O-acyltransferase (membrane bound) domain containing...    50   4e-06
gi|225703081 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703079 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703033 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703037 membrane bound O-acyltransferase domain containing ...    37   0.049
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]             34   0.32 
gi|19424128 alkaline ceramidase 1 [Homo sapiens]                       32   0.93 
gi|52317265 olfactory receptor, family 51, subfamily I, member 2...    32   0.93 
gi|221316556 ATP-binding cassette, sub-family C, member 3 isofor...    30   4.6  
gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform ...    30   4.6  
gi|4885335 G protein-coupled receptor 4 [Homo sapiens]                 30   4.6  
gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]                    30   4.6  
gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]             30   6.0  
gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]       30   6.0  
gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ...    29   7.9  

>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score =  944 bits (2441), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240

Query: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300

Query: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360

Query: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420

Query: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461


>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score =  929 bits (2400), Expect = 0.0
 Identities = 456/461 (98%), Positives = 456/461 (98%), Gaps = 5/461 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA     R
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA-----R 235

Query: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 236 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 295

Query: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 296 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 355

Query: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 356 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 415

Query: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 416 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score =  925 bits (2391), Expect = 0.0
 Identities = 454/461 (98%), Positives = 455/461 (98%), Gaps = 6/461 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR      +GTMVR
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KGTMVR 234

Query: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 235 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 294

Query: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 295 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 354

Query: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 355 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 414

Query: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 415 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 455


>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score =  914 bits (2361), Expect = 0.0
 Identities = 449/461 (97%), Positives = 450/461 (97%), Gaps = 11/461 (2%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR           +
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR-----------K 229

Query: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 230 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 289

Query: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 290 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 349

Query: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 350 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 409

Query: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 410 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450


>gi|45439337 porcupine isoform E [Homo sapiens]
          Length = 379

 Score =  767 bits (1981), Expect = 0.0
 Identities = 378/390 (96%), Positives = 379/390 (97%), Gaps = 11/390 (2%)

Query: 72  MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 131
           MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA
Sbjct: 1   MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 60

Query: 132 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 191
           MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ
Sbjct: 61  MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 120

Query: 192 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSF 251
           KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR           +WLRAYESAVSF
Sbjct: 121 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR-----------KWLRAYESAVSF 169

Query: 252 HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY 311
           HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY
Sbjct: 170 HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY 229

Query: 312 WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI 371
           WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI
Sbjct: 230 WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI 289

Query: 372 LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG 431
           LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG
Sbjct: 290 LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG 349

Query: 432 MAYTVHKWSELSWASHWVTFGCWIFYRLIG 461
           MAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 350 MAYTVHKWSELSWASHWVTFGCWIFYRLIG 379


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 62/273 (22%), Positives = 107/273 (39%), Gaps = 34/273 (12%)

Query: 79  SLLCYLVLFLCRHSSHRGVFLSVTI----LIYLLMGEMHMVDTVTWHKMRGAQMIVAMKA 134
           SLLC ++ FL      R +   +T     + YLL G  +        K      ++ +K 
Sbjct: 93  SLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKL 152

Query: 135 VSLGFD-LDRGE-------------VGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           + L  D  D G+             +  VPS +E  G+ YF G  + GP  S + Y++ V
Sbjct: 153 IGLAVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLV 212

Query: 181 QGRPLSC-----RWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKAR 235
           QG  +         +    + L+L L  LV  T + P++   ++      L  +      
Sbjct: 213 QGELIDIPGKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYL------LTEDYDNHPF 266

Query: 236 GTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVS-KPLNV 292
                ++  +   V + +   ++  ++E    L G GF   EEK   +WD   + K    
Sbjct: 267 WFRCMYMLIWGKFVLYKYVTCWL--VTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLF 324

Query: 293 ELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLG 325
           E        + S+N+  + W+  Y+FK    LG
Sbjct: 325 ETNPRFTGTIASFNINTNAWVARYIFKRLKFLG 357


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 81/352 (23%), Positives = 145/352 (41%), Gaps = 57/352 (16%)

Query: 49  SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
           S ++HA     G + +   F  + V + +L L+CY ++     S+ HR   F+++  L  
Sbjct: 61  SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120

Query: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
             +  +++    +      G  MIV  K  +L F +  G                +   P
Sbjct: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180

Query: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
           S +E++ YL    +++ GP  +F  Y+  ++G+      L   W +K             
Sbjct: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240

Query: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSFH 252
           V   L + L+ L+L   +    FP    L  D  +      AR   + +L     A    
Sbjct: 241 VIHKLGITLVSLLLFLTL-TKTFPVTC-LVDDWFVHKASFPAR---LCYLYVVMQASKPK 295

Query: 253 FSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPM 309
           +  YF   L++A    AG GF+  ++  +  WDL  +  +  +E   S    + +WN+  
Sbjct: 296 Y--YFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQT 353

Query: 310 SYWLNNYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 355
           + WL    ++   R+  +  VL T+  SAL HG      F+F L  +L++LA
Sbjct: 354 ATWLKCVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400


>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 78/368 (21%), Positives = 146/368 (39%), Gaps = 47/368 (12%)

Query: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91

Query: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149

Query: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209

Query: 188 RW----------LQKVARSLALALLCLVLSTCVGPYLFPYFI--PLNGDRLLRNKKRKAR 235
                        ++   S   A++  +L  C    LF   I   L  +  +    +   
Sbjct: 210 TQSGENGKEETQYERTEPSPNTAVVQKLL-VCGLSLLFHLTICTTLPVEYNIDEHFQATA 268

Query: 236 GTMVRWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN-V 292
               + +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  +
Sbjct: 269 SWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQI 328

Query: 293 ELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFHL 347
           E+  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   L
Sbjct: 329 EMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTFL 384

Query: 348 AAVLLSLA 355
             VL++LA
Sbjct: 385 TGVLMTLA 392


>gi|225703081 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 48/261 (18%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244
             L  +LS+ + P         Y  P      Y IP+     +R          V W+ A
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 179

Query: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295
               ++  F  Y V     A    AG G T         E+   LE+D    + ++    
Sbjct: 180 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 234

Query: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLA 348
              V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+     
Sbjct: 235 DFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFL 294

Query: 349 AVLLSLAFITYVEHVLRKRLA 369
            + L LA    +E  LR RL+
Sbjct: 295 TIPLCLAAEGRLESALRGRLS 315


>gi|225703079 membrane bound O-acyltransferase domain containing 7
           isoform 1 [Homo sapiens]
          Length = 472

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 48/261 (18%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244
             L  +LS+ + P         Y  P      Y IP+     +R          V W+ A
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 252

Query: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295
               ++  F  Y V     A    AG G T         E+   LE+D    + ++    
Sbjct: 253 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 307

Query: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLA 348
              V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+     
Sbjct: 308 DFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFL 367

Query: 349 AVLLSLAFITYVEHVLRKRLA 369
            + L LA    +E  LR RL+
Sbjct: 368 TIPLCLAAEGRLESALRGRLS 388


>gi|225703033 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 48/261 (18%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244
             L  +LS+ + P         Y  P      Y IP+     +R          V W+ A
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 179

Query: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295
               ++  F  Y V     A    AG G T         E+   LE+D    + ++    
Sbjct: 180 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 234

Query: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLA 348
              V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+     
Sbjct: 235 DFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFL 294

Query: 349 AVLLSLAFITYVEHVLRKRLA 369
            + L LA    +E  LR RL+
Sbjct: 295 TIPLCLAAEGRLESALRGRLS 315


>gi|225703037 membrane bound O-acyltransferase domain containing 7
           isoform 3 [Homo sapiens]
          Length = 344

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 53/209 (25%), Positives = 81/209 (38%), Gaps = 44/209 (21%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244
             L  +LS+ + P         Y  P      Y IP+     +R          V W+ A
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 252

Query: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295
               ++  F  Y V     A    AG G T         E+   LE+D    + ++    
Sbjct: 253 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 307

Query: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNA 321
              V V   +  WN+ + +WL  Y++K+A
Sbjct: 308 DFCVRVRDGMRYWNMTVQWWLAQYIYKSA 336


>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
          Length = 1496

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 32  LLAICLA--CRLLWRLGLPSYLKHASTVAGGFFSLYHFF-QLHMVWVVLLSLLCYLVLF- 87
           L A CL   C  LW L LP+Y++ A +      + YH   Q+    VVL   +CY VL  
Sbjct: 762 LWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQ 821

Query: 88  LCRH 91
           LC H
Sbjct: 822 LCSH 825


>gi|19424128 alkaline ceramidase 1 [Homo sapiens]
          Length = 264

 Score = 32.3 bits (72), Expect = 0.93
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215


>gi|52317265 olfactory receptor, family 51, subfamily I, member 2
           [Homo sapiens]
          Length = 312

 Score = 32.3 bits (72), Expect = 0.93
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 14/94 (14%)

Query: 299 VEVVTSWNLPMSYWLNNYVFKN-ALRLGTFSAVLVTYAASA-------------LLHGFS 344
           V V  S + PM Y+L+   F + A+ + T   VL T+  +A             L+H FS
Sbjct: 49  VRVEPSLHEPMYYFLSMLSFSDVAISMATLPTVLRTFCLNARNITFDACLIQMFLIHFFS 108

Query: 345 FHLAAVLLSLAFITYVEHVLRKRLARILSACVLS 378
              + +LL+++F  YV      R A +L+  V++
Sbjct: 109 MMESGILLAMSFDRYVAICDPLRYATVLTTEVIA 142


>gi|221316556 ATP-binding cassette, sub-family C, member 3 isoform 2
           [Homo sapiens]
          Length = 572

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform 1
           [Homo sapiens]
          Length = 1527

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
          Length = 362

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 158 YLYFVGTIVFGPW----ISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           Y  FVG +   PW    +S+   L+AV+G   + R  +   + LAL+L+ +VL  C  PY
Sbjct: 184 YRVFVGFLF--PWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVL-VCFAPY 240


>gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]
          Length = 353

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 154 EFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           +F+ Y + VGT V    I   +  QA++  P  CRW++   RS      C +L  C  P+
Sbjct: 122 KFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLL--CWAPH 179

Query: 214 L 214
           +
Sbjct: 180 V 180


>gi|23238240 angiotensin II receptor, type 2 [Homo sapiens]
          Length = 363

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 9/85 (10%)

Query: 170 WISFH--SYLQAV--QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDR 225
           W+ FH  ++L A+   G   SC  +  +  +L  A+L    ++CV P+L+ +     G+R
Sbjct: 269 WLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFV----GNR 324

Query: 226 LLRNKKRKARGTMVRWLRAYESAVS 250
             + K R      + WL+    ++S
Sbjct: 325 -FQQKLRSVFRVPITWLQGKRESMS 348


>gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]
          Length = 522

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 304 SWNLPMSYWLNNYVFKNALRL----GTFSAVLVTYAASALLHGFSF 345
           +WN+ +  WL +YV+++ LRL        A+L  +  SA+ H + F
Sbjct: 393 TWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIF 438


>gi|164519076 transmembrane 9 superfamily protein member 4 [Homo
           sapiens]
          Length = 642

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 4/34 (11%)

Query: 420 DVDDTTEEQGYGMAYTVHKW--SELSWASHWVTF 451
           ++D T E Q Y   Y+VH W  S++ WAS W T+
Sbjct: 239 EIDPTKENQLY-FTYSVH-WEESDIKWASRWDTY 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.141    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,123,550
Number of Sequences: 37866
Number of extensions: 705065
Number of successful extensions: 1860
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1839
Number of HSP's gapped (non-prelim): 26
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.