Search of human proteins with 45439329

Search of human proteins with 45439329

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45439329 porcupine isoform A [Homo sapiens]
         (450 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45439329 porcupine isoform A [Homo sapiens]                        923   0.0  
gi|45439333 porcupine isoform C [Homo sapiens]                        917   0.0  
gi|45439331 porcupine isoform B [Homo sapiens]                        915   0.0  
gi|45439335 porcupine isoform D [Homo sapiens]                        914   0.0  
gi|45439337 porcupine isoform E [Homo sapiens]                        777   0.0  
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    60   4e-09
gi|122937404 membrane bound O-acyltransferase domain containing ...    56   6e-08
gi|40548387 O-acyltransferase (membrane bound) domain containing...    50   3e-06
gi|225703081 membrane bound O-acyltransferase domain containing ...    44   3e-04
gi|225703079 membrane bound O-acyltransferase domain containing ...    44   3e-04
gi|225703033 membrane bound O-acyltransferase domain containing ...    44   3e-04
gi|225703037 membrane bound O-acyltransferase domain containing ...    40   0.006
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]             34   0.31 
gi|19424128 alkaline ceramidase 1 [Homo sapiens]                       32   0.90 
gi|52317265 olfactory receptor, family 51, subfamily I, member 2...    32   0.90 
gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]       31   2.6  
gi|221316556 ATP-binding cassette, sub-family C, member 3 isofor...    30   4.5  
gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform ...    30   4.5  
gi|4885335 G protein-coupled receptor 4 [Homo sapiens]                 30   4.5  
gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]                    30   4.5  
gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ...    29   7.6  

>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score =  923 bits (2386), Expect = 0.0
 Identities = 450/450 (100%), Positives = 450/450 (100%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSF 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSF
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSF 240

Query: 241 HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY 300
           HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY
Sbjct: 241 HFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSY 300

Query: 301 WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI 360
           WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI
Sbjct: 301 WLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARI 360

Query: 361 LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG 420
           LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG
Sbjct: 361 LSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYG 420

Query: 421 MAYTVHKWSELSWASHWVTFGCWIFYRLIG 450
           MAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 MAYTVHKWSELSWASHWVTFGCWIFYRLIG 450


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score =  917 bits (2370), Expect = 0.0
 Identities = 450/455 (98%), Positives = 450/455 (98%), Gaps = 5/455 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRK-----WLRAYE 235
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRK     WLRAYE
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKGTMVRWLRAYE 240

Query: 236 SAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWN 295
           SAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWN
Sbjct: 241 SAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWN 300

Query: 296 LPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRK 355
           LPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRK
Sbjct: 301 LPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRK 360

Query: 356 RLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTE 415
           RLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTE
Sbjct: 361 RLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTE 420

Query: 416 EQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450
           EQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 EQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 455


>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score =  915 bits (2366), Expect = 0.0
 Identities = 449/456 (98%), Positives = 450/456 (98%), Gaps = 6/456 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KWLRAY 234
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR      +WLRAY
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240

Query: 235 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 294
           ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW
Sbjct: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300

Query: 295 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 354
           NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR
Sbjct: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360

Query: 355 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 414
           KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT
Sbjct: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420

Query: 415 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450
           EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456


>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score =  914 bits (2361), Expect = 0.0
 Identities = 449/461 (97%), Positives = 450/461 (97%), Gaps = 11/461 (2%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR-----------K 229
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR           +
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240

Query: 230 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 289
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300

Query: 290 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 349
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360

Query: 350 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 409
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420

Query: 410 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461


>gi|45439337 porcupine isoform E [Homo sapiens]
          Length = 379

 Score =  777 bits (2006), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 72  MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 131
           MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA
Sbjct: 1   MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 60

Query: 132 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 191
           MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ
Sbjct: 61  MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 120

Query: 192 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFSNYFVGFLS 251
           KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFSNYFVGFLS
Sbjct: 121 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFSNYFVGFLS 180

Query: 252 EATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNAL 311
           EATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNAL
Sbjct: 181 EATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNAL 240

Query: 312 RLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACVLSKRCP 371
           RLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACVLSKRCP
Sbjct: 241 RLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACVLSKRCP 300

Query: 372 PDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSEL 431
           PDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSEL
Sbjct: 301 PDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTVHKWSEL 360

Query: 432 SWASHWVTFGCWIFYRLIG 450
           SWASHWVTFGCWIFYRLIG
Sbjct: 361 SWASHWVTFGCWIFYRLIG 379


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 65/265 (24%), Positives = 103/265 (38%), Gaps = 29/265 (10%)

Query: 79  SLLCYLVLFLCRHSSHRGVFLSVTI----LIYLLMGEMHMVDTVTWHKMRGAQMIVAMKA 134
           SLLC ++ FL      R +   +T     + YLL G  +        K      ++ +K 
Sbjct: 93  SLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKL 152

Query: 135 VSLGFD-LDRGE-------------VGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           + L  D  D G+             +  VPS +E  G+ YF G  + GP  S + Y++ V
Sbjct: 153 IGLAVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLV 212

Query: 181 QGRPLSC-----RWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKWLRAYE 235
           QG  +         +    + L+L L  LV  T + P++   ++          W R   
Sbjct: 213 QGELIDIPGKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFWFRCMY 272

Query: 236 SAV--SFHFSNYFVGFL-SEATATLAGAGFT--EEKDHLEWDLTVS-KPLNVELPRSMVE 289
             +   F    Y   +L +E    L G GF   EEK   +WD   + K    E       
Sbjct: 273 MLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTG 332

Query: 290 VVTSWNLPMSYWLNNYVFKNALRLG 314
            + S+N+  + W+  Y+FK    LG
Sbjct: 333 TIASFNINTNAWVARYIFKRLKFLG 357


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 79/350 (22%), Positives = 143/350 (40%), Gaps = 64/350 (18%)

Query: 49  SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
           S ++HA     G + +   F  + V + +L L+CY ++     S+ HR   F+++  L  
Sbjct: 61  SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120

Query: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
             +  +++    +      G  MIV  K  +L F +  G                +   P
Sbjct: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180

Query: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
           S +E++ YL    +++ GP  +F  Y+  ++G+      L   W +K             
Sbjct: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240

Query: 193 VARSLALALLCLVL---------STCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFS 243
           V   L + L+ L+L          TC+    F +       RL   ++    S   +   
Sbjct: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPA-RLCYLYVVMQASKPKY--- 296

Query: 244 NYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSY 300
            YF   L++A    AG GF+  ++  +  WDL  +  +  +E   S    + +WN+  + 
Sbjct: 297 -YFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTAT 355

Query: 301 WLNNYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 344
           WL    ++   R+  +  VL T+  SAL HG      F+F L  +L++LA
Sbjct: 356 WLKCVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400


>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 76/367 (20%), Positives = 142/367 (38%), Gaps = 56/367 (15%)

Query: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91

Query: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149

Query: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209

Query: 188 RWLQK------------------VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRK 229
               +                  V + L +  L L+    +   L   +      +    
Sbjct: 210 TQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLFHLTICTTLPVEYNIDEHFQATAS 269

Query: 230 W----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN-VE 282
           W    +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  +E
Sbjct: 270 WPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIE 329

Query: 283 LPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFHLA 337
           +  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   L 
Sbjct: 330 MSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTFLT 385

Query: 338 AVLLSLA 344
            VL++LA
Sbjct: 386 GVLMTLA 392


>gi|225703081 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 186

Query: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 187 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 241

Query: 291 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 344
             +  WN+ + +WL  Y++K+A           T   SA  H    G+      + L LA
Sbjct: 242 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 301

Query: 345 FITYVEHVLRKRLA 358
               +E  LR RL+
Sbjct: 302 AEGRLESALRGRLS 315


>gi|225703079 membrane bound O-acyltransferase domain containing 7
           isoform 1 [Homo sapiens]
          Length = 472

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 259

Query: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 260 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 314

Query: 291 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 344
             +  WN+ + +WL  Y++K+A           T   SA  H    G+      + L LA
Sbjct: 315 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 374

Query: 345 FITYVEHVLRKRLA 358
               +E  LR RL+
Sbjct: 375 AEGRLESALRGRLS 388


>gi|225703033 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 186

Query: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 187 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 241

Query: 291 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 344
             +  WN+ + +WL  Y++K+A           T   SA  H    G+      + L LA
Sbjct: 242 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 301

Query: 345 FITYVEHVLRKRLA 358
               +E  LR RL+
Sbjct: 302 AEGRLESALRGRLS 315


>gi|225703037 membrane bound O-acyltransferase domain containing 7
           isoform 3 [Homo sapiens]
          Length = 344

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/202 (24%), Positives = 77/202 (38%), Gaps = 41/202 (20%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 259

Query: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 260 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 314

Query: 291 --VTSWNLPMSYWLNNYVFKNA 310
             +  WN+ + +WL  Y++K+A
Sbjct: 315 DGMRYWNMTVQWWLAQYIYKSA 336


>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
          Length = 1496

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 32  LLAICLA--CRLLWRLGLPSYLKHASTVAGGFFSLYHFF-QLHMVWVVLLSLLCYLVLF- 87
           L A CL   C  LW L LP+Y++ A +      + YH   Q+    VVL   +CY VL  
Sbjct: 762 LWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQ 821

Query: 88  LCRH 91
           LC H
Sbjct: 822 LCSH 825


>gi|19424128 alkaline ceramidase 1 [Homo sapiens]
          Length = 264

 Score = 32.3 bits (72), Expect = 0.90
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215


>gi|52317265 olfactory receptor, family 51, subfamily I, member 2
           [Homo sapiens]
          Length = 312

 Score = 32.3 bits (72), Expect = 0.90
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 14/94 (14%)

Query: 288 VEVVTSWNLPMSYWLNNYVFKN-ALRLGTFSAVLVTYAASA-------------LLHGFS 333
           V V  S + PM Y+L+   F + A+ + T   VL T+  +A             L+H FS
Sbjct: 49  VRVEPSLHEPMYYFLSMLSFSDVAISMATLPTVLRTFCLNARNITFDACLIQMFLIHFFS 108

Query: 334 FHLAAVLLSLAFITYVEHVLRKRLARILSACVLS 367
              + +LL+++F  YV      R A +L+  V++
Sbjct: 109 MMESGILLAMSFDRYVAICDPLRYATVLTTEVIA 142


>gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]
          Length = 522

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 51/203 (25%), Positives = 76/203 (37%), Gaps = 34/203 (16%)

Query: 143 RGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALL 202
           RGE    PS   F  YLYF+    F P + +         R    RW   VA++ A AL 
Sbjct: 259 RGEGIQAPS---FSSYLYFL----FCPTLIYRE----TYPRTPYVRW-NYVAKNFAQALG 306

Query: 203 CLVLSTC--VGPYLFPYFI-----PLNGDRLLRKWLRAYESAVSFHFSNYFVGFLSEATA 255
           C VL  C  +G    P F      P +   L+   L A    +      +F        A
Sbjct: 307 C-VLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNA 365

Query: 256 TLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRL-- 313
                 F +   + +W  + S                +WN+ +  WL +YV+++ LRL  
Sbjct: 366 FAEMLRFGDRMFYRDWWNSTS----------FSNYYRTWNVVVHDWLYSYVYQDGLRLLG 415

Query: 314 --GTFSAVLVTYAASALLHGFSF 334
                 A+L  +  SA+ H + F
Sbjct: 416 ARARGVAMLGVFLVSAVAHEYIF 438


>gi|221316556 ATP-binding cassette, sub-family C, member 3 isoform 2
           [Homo sapiens]
          Length = 572

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform 1
           [Homo sapiens]
          Length = 1527

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
          Length = 362

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 158 YLYFVGTIVFGPW----ISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           Y  FVG +   PW    +S+   L+AV+G   + R  +   + LAL+L+ +VL  C  PY
Sbjct: 184 YRVFVGFLF--PWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVL-VCFAPY 240


>gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]
          Length = 353

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)

Query: 154 EFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           +F+ Y + VGT V    I   +  QA++  P  CRW++   RS      C +L  C  P+
Sbjct: 122 KFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLL--CWAPH 179

Query: 214 L 214
           +
Sbjct: 180 V 180


>gi|164519076 transmembrane 9 superfamily protein member 4 [Homo
           sapiens]
          Length = 642

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 4/34 (11%)

Query: 409 DVDDTTEEQGYGMAYTVHKW--SELSWASHWVTF 440
           ++D T E Q Y   Y+VH W  S++ WAS W T+
Sbjct: 239 EIDPTKENQLY-FTYSVH-WEESDIKWASRWDTY 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.141    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,831,225
Number of Sequences: 37866
Number of extensions: 694618
Number of successful extensions: 1843
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1822
Number of HSP's gapped (non-prelim): 25
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.