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Search of human proteins with 45433552
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
(874 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 1770 0.0
gi|163792198 latrophilin 3 precursor [Homo sapiens] 230 4e-60
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 228 1e-59
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 228 1e-59
gi|6912464 latrophilin 2 precursor [Homo sapiens] 218 2e-56
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 213 6e-55
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 208 2e-53
gi|40807489 egf-like module containing, mucin-like, hormone rece... 203 6e-52
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 198 2e-50
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 194 2e-49
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 191 2e-48
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 191 2e-48
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 191 2e-48
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 189 7e-48
gi|240120161 G protein-coupled receptor 144 [Homo sapiens] 184 4e-46
gi|23397681 egf-like module containing, mucin-like, hormone rece... 179 1e-44
gi|23397687 egf-like module containing, mucin-like, hormone rece... 179 1e-44
gi|23397685 egf-like module containing, mucin-like, hormone rece... 179 1e-44
gi|23397683 egf-like module containing, mucin-like, hormone rece... 179 1e-44
gi|23397693 egf-like module containing, mucin-like, hormone rece... 177 3e-44
gi|23397691 egf-like module containing, mucin-like, hormone rece... 177 3e-44
gi|23397689 egf-like module containing, mucin-like, hormone rece... 177 3e-44
gi|148719671 G-protein coupled receptor 116 [Homo sapiens] 165 2e-40
gi|148719673 G-protein coupled receptor 116 [Homo sapiens] 165 2e-40
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 159 1e-38
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 159 1e-38
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens] 159 1e-38
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens] 159 1e-38
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 158 2e-38
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 155 2e-37
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 1770 bits (4585), Expect = 0.0
Identities = 874/874 (100%), Positives = 874/874 (100%)
Query: 1 MEKLLRLCCWYSWLLLFYYNFQVRGVYSRSQDHPGFQVLASASHYWPLENVDGIHELQDT 60
MEKLLRLCCWYSWLLLFYYNFQVRGVYSRSQDHPGFQVLASASHYWPLENVDGIHELQDT
Sbjct: 1 MEKLLRLCCWYSWLLLFYYNFQVRGVYSRSQDHPGFQVLASASHYWPLENVDGIHELQDT 60
Query: 61 TGDIVEGKVNKGIYLKEEKGVTLLYYGRYNSSCISKPEQCGPEGVTFSFFWKTQGEQSRP 120
TGDIVEGKVNKGIYLKEEKGVTLLYYGRYNSSCISKPEQCGPEGVTFSFFWKTQGEQSRP
Sbjct: 61 TGDIVEGKVNKGIYLKEEKGVTLLYYGRYNSSCISKPEQCGPEGVTFSFFWKTQGEQSRP 120
Query: 121 IPSAYGGQVISNGFKVCSSGGRGSVELYTRDNSMTWEASFSPPGPYWTHVLFTWKSKEGL 180
IPSAYGGQVISNGFKVCSSGGRGSVELYTRDNSMTWEASFSPPGPYWTHVLFTWKSKEGL
Sbjct: 121 IPSAYGGQVISNGFKVCSSGGRGSVELYTRDNSMTWEASFSPPGPYWTHVLFTWKSKEGL 180
Query: 181 KVYVNGTLSTSDPSGKVSRDYGESNVNLVIGSEQDQAKCYENGAFDEFIIWERALTPDEI 240
KVYVNGTLSTSDPSGKVSRDYGESNVNLVIGSEQDQAKCYENGAFDEFIIWERALTPDEI
Sbjct: 181 KVYVNGTLSTSDPSGKVSRDYGESNVNLVIGSEQDQAKCYENGAFDEFIIWERALTPDEI 240
Query: 241 AMYFTAAIGKHALLSSTLPSLFMTSTASPVMPTDAYHPIITNLTEERKTFQSPGVILSYL 300
AMYFTAAIGKHALLSSTLPSLFMTSTASPVMPTDAYHPIITNLTEERKTFQSPGVILSYL
Sbjct: 241 AMYFTAAIGKHALLSSTLPSLFMTSTASPVMPTDAYHPIITNLTEERKTFQSPGVILSYL 300
Query: 301 QNVSLSLPSKSLSEQTALNLTKTFLKAVGEILLLPGWIALSEDSAVVLSLIDTIDTVMGH 360
QNVSLSLPSKSLSEQTALNLTKTFLKAVGEILLLPGWIALSEDSAVVLSLIDTIDTVMGH
Sbjct: 301 QNVSLSLPSKSLSEQTALNLTKTFLKAVGEILLLPGWIALSEDSAVVLSLIDTIDTVMGH 360
Query: 361 VSSNLHGSTPQVTVEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAW 420
VSSNLHGSTPQVTVEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAW
Sbjct: 361 VSSNLHGSTPQVTVEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAW 420
Query: 421 STVVGLLYHSMHYYLNNIWPAHTKIAEAMHHQDCLLFATSHLISLEVSPPPTLSQNLSGS 480
STVVGLLYHSMHYYLNNIWPAHTKIAEAMHHQDCLLFATSHLISLEVSPPPTLSQNLSGS
Sbjct: 421 STVVGLLYHSMHYYLNNIWPAHTKIAEAMHHQDCLLFATSHLISLEVSPPPTLSQNLSGS 480
Query: 481 PLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCR 540
PLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCR
Sbjct: 481 PLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCR 540
Query: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ
Sbjct: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
Query: 601 RYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM 660
RYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM
Sbjct: 601 RYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM 660
Query: 661 VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPA 720
VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPA
Sbjct: 661 VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPA 720
Query: 721 LFVIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAV 780
LFVIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAV
Sbjct: 721 LFVIVVNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAV 780
Query: 781 NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFH 840
NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFH
Sbjct: 781 NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFH 840
Query: 841 SDLMNGTRPGMASTKLSPWDKSSHSAHRVDLSAV 874
SDLMNGTRPGMASTKLSPWDKSSHSAHRVDLSAV
Sbjct: 841 SDLMNGTRPGMASTKLSPWDKSSHSAHRVDLSAV 874
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 230 bits (587), Expect = 4e-60
Identities = 130/358 (36%), Positives = 194/358 (54%), Gaps = 20/358 (5%)
Query: 510 CAFLDFSSGE--GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARG-HQVAL 566
C+F +S G WS GC L N T++ C C HLTNFA+LM V ++ + H + L
Sbjct: 818 CSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLL 877
Query: 567 SSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLE 626
I++VG LS++CL+ + TF + + RN IH NL ++ VA++L LI
Sbjct: 878 DVITWVGILLSLVCLLICIFTFCFFRGLQSDRNT---IHKNLCISLFVAELLFLIGINRT 934
Query: 627 PGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C V A LLH+FFL+AF WM +EG+ LY M+++VF SE S+ +Y+Y +G+G P LI
Sbjct: 935 DQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALI 994
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGIL-IAVTRVISQIS--- 742
+S + SYGT CWL L + IW+F+ PA +I++N+ L IA+ ++ +
Sbjct: 995 VAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILK 1054
Query: 743 -----ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSL 797
DN + K LL +LG +W FG++ +N V+ Y+F NSL
Sbjct: 1055 PESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSL 1114
Query: 798 QGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNGTR-PGMAST 854
QG+FIF+FHC+L +VR + + + S +S S +G+R PG ST
Sbjct: 1115 QGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESS----IGSGKTSGSRTPGRYST 1168
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 228 bits (582), Expect = 1e-59
Identities = 125/328 (38%), Positives = 186/328 (56%), Gaps = 16/328 (4%)
Query: 496 HSEATNSSNRVFVYCAFLDFSSGE--GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQV 553
H E N N C+F ++S G WS GC L N T++ C C+HLTNFA+LM
Sbjct: 791 HLEDKNHFN---ANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAH 847
Query: 554 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVL 613
+ R +++ LS I++VG +S++CL + TF L + T RN IH NL +
Sbjct: 848 REIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNT---IHKNLCINLF 904
Query: 614 VAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHR 673
+A++L L+ C + A LLHYFFL+AF+W+ +EG+HLY ++++VF SE S+ +
Sbjct: 905 LAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTK 964
Query: 674 YYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA 733
YYY G+ FP L+ I+ + SYGT CWL + + IW+F+ P FVIVVN+ L+
Sbjct: 965 YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMV 1024
Query: 734 ----VTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQY 789
+ R S + D+ ++ K A LL +LG +W FG+L +N +VV Y
Sbjct: 1025 TLHKMIRSSSVLKPDSSRLDN----IKSWALGAIALLFLLGLTWAFGLLFINKESVVMAY 1080
Query: 790 MFATLNSLQGLFIFLFHCLLNSEVRAAF 817
+F T N+ QG+FIF+FHC L +V +
Sbjct: 1081 LFTTFNAFQGVFIFVFHCALQKKVHKEY 1108
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 228 bits (582), Expect = 1e-59
Identities = 125/328 (38%), Positives = 186/328 (56%), Gaps = 16/328 (4%)
Query: 496 HSEATNSSNRVFVYCAFLDFSSGE--GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQV 553
H E N N C+F ++S G WS GC L N T++ C C+HLTNFA+LM
Sbjct: 786 HLEDKNHFN---ANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAH 842
Query: 554 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVL 613
+ R +++ LS I++VG +S++CL + TF L + T RN IH NL +
Sbjct: 843 REIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNT---IHKNLCINLF 899
Query: 614 VAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHR 673
+A++L L+ C + A LLHYFFL+AF+W+ +EG+HLY ++++VF SE S+ +
Sbjct: 900 LAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTK 959
Query: 674 YYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA 733
YYY G+ FP L+ I+ + SYGT CWL + + IW+F+ P FVIVVN+ L+
Sbjct: 960 YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMV 1019
Query: 734 ----VTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQY 789
+ R S + D+ ++ K A LL +LG +W FG+L +N +VV Y
Sbjct: 1020 TLHKMIRSSSVLKPDSSRLDN----IKSWALGAIALLFLLGLTWAFGLLFINKESVVMAY 1075
Query: 790 MFATLNSLQGLFIFLFHCLLNSEVRAAF 817
+F T N+ QG+FIF+FHC L +V +
Sbjct: 1076 LFTTFNAFQGVFIFVFHCALQKKVHKEY 1103
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 218 bits (555), Expect = 2e-56
Identities = 153/511 (29%), Positives = 251/511 (49%), Gaps = 42/511 (8%)
Query: 341 SEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVTVEGSSAMAEFSVAKILPKTVNSSHYRF 400
SE + L+DT++ ++ NL T +V++ + + E +V L ++F
Sbjct: 618 SEQAHTATMLLDTLEEGAFVLADNLLEPT-RVSMPTENIVLEVAV---LSTEGQIQDFKF 673
Query: 401 PAH---GQSFIQIPHEAFH---RHAWSTVVGLLYHSMHYYLNNIWPAHTKIAEAMHHQDC 454
P S IQ+ R+ + +V ++Y S+ +L+ A K+ ++
Sbjct: 674 PLGIKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTE-NATIKLGADFIGRNS 732
Query: 455 LLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLD 514
+ SH+IS+ ++ + L+ L T+ H + N N C+F +
Sbjct: 733 TIAVNSHVISVSINKESSRVY-LTDPVLFTL---------PHIDPDNYFN---ANCSFWN 779
Query: 515 FSSGE--GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARG-HQVALSSISY 571
+S G WS GC L N T + C C+HLTNFAILM + G H++ L+ I++
Sbjct: 780 YSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITW 839
Query: 572 VGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTP 631
VG +S++CL + TF + + RN IH NL + +A+ + LI
Sbjct: 840 VGIVISLVCLAICIFTFCFFRGLQSDRNT---IHKNLCINLFIAEFIFLIGIDKTKYAIA 896
Query: 632 CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISL 691
C + A LLH+FFL+AFAWM +EG+ LY M+++VF SE S+ +YYY G+ FP + +S
Sbjct: 897 CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSA 956
Query: 692 SFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILI----AVTRVISQISADNYK 747
+ SYGT CWL + + IW+F+ P F+I++NI L+ + + + + D+ +
Sbjct: 957 AIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSR 1016
Query: 748 IHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHC 807
+ K LL +LG +W FG+L +N +V Y+F N+ QG+FIF+FHC
Sbjct: 1017 LEN----IKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHC 1072
Query: 808 LLNSEVR----AAFKHKTKVWSLTSSSARTS 834
L +VR F+H L + S +S
Sbjct: 1073 ALQKKVRKEYGKCFRHSYCCGGLPTESPHSS 1103
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 213 bits (542), Expect = 6e-55
Identities = 127/364 (34%), Positives = 200/364 (54%), Gaps = 27/364 (7%)
Query: 460 SHLISLEVSP-PPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSG 518
S +IS+ +S PPTL + IT L HR ++R CAF ++S
Sbjct: 333 SSVISVSMSSNPPTLYE----LEKITFTLSHRKV----------TDRYRSLCAFWNYSPD 378
Query: 519 --EGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSL 576
G WS+ GC LT N T++ CRC HLT+FAILM P + + + L+ I+ +G +
Sbjct: 379 TMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNI-LTRITQLGIII 437
Query: 577 SVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMA 636
S++CL + TF S + + R IH NL ++ +A+++ L+ C ++A
Sbjct: 438 SLICLAICIFTFWFFSEIQSTRTT---IHKNLCCSLFLAELVFLVGINTNTNKLFCSIIA 494
Query: 637 VLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMD 696
LLHYFFL+AFAWM +EG+HLY +V+ V ++ H+ +Y G+ P ++ S +
Sbjct: 495 GLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYR 554
Query: 697 SYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNYKIHGDPSAF- 755
YGT+ CWLS + IW+F+ PA +I+VN L+A +I ++ + + S F
Sbjct: 555 YYGTTKVCWLSTENNFIWSFIGPACLIILVN---LLAFGVIIYKVFRHTAGLKPEVSCFE 611
Query: 756 --KLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEV 813
+ A+ LL +LGT+W+FGVL V +VV Y+F N+ QG+FIFLF C+L+ ++
Sbjct: 612 NIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKI 671
Query: 814 RAAF 817
+ +
Sbjct: 672 QEEY 675
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 208 bits (529), Expect = 2e-53
Identities = 117/314 (37%), Positives = 171/314 (54%), Gaps = 16/314 (5%)
Query: 510 CAFLDFS---SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVAL 566
C F + S G G WS GC L N T+ C+C+H +FA+LM + E G + L
Sbjct: 2411 CVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRRE--NGEVLPL 2468
Query: 567 SSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLE 626
++Y SLS L A LV F +LS V +R+ + IH +L+ A+ ++Q++ +I
Sbjct: 2469 KIVTYAAVSLS---LAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQT 2525
Query: 627 PGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C V+A+LLHY ++S FAW LVE LH+Y M+ +V + R+YY +GWG P ++
Sbjct: 2526 ENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIV 2585
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNY 746
+++ YG + CWLSL IW+F P VI++N VT V+S +
Sbjct: 2586 TGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIIN-----TVTSVLSAKVSCQR 2640
Query: 747 KIH--GDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFL 804
K H G L A +LL ++ +W+ G+LAVN A+ F Y+FA + LQG F+ L
Sbjct: 2641 KHHYYGKKGIVSLLRTAFLLLL-LISATWLLGLLAVNRDALSFHYLFAIFSGLQGPFVLL 2699
Query: 805 FHCLLNSEVRAAFK 818
FHC+LN EVR K
Sbjct: 2700 FHCVLNQEVRKHLK 2713
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 203 bits (516), Expect = 6e-52
Identities = 116/321 (36%), Positives = 172/321 (53%), Gaps = 14/321 (4%)
Query: 520 GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVL 579
G W++ GC + + TY++C C + N A++M L + +L IS+VG +S++
Sbjct: 560 GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM----DFSLYIISHVGIIISLV 615
Query: 580 CLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLL 639
CLV + TF + S IRN ++H +L +L+A+ L L C ++A L
Sbjct: 616 CLVLAIATFLLCRS---IRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFL 672
Query: 640 HYFFLSAFAWMLVEGLHLYSMV-----IKVFGSEDSKHRYYYGMGWGFPLLICIISLSFA 694
HY FL+ F WMLVE + L+ MV + F S + K + G+G P+L+ +IS S
Sbjct: 673 HYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQ 732
Query: 695 MDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQ-ISADNYKIHGDPS 753
YG N CWL+ +G IW+F+ P VIV+N +L ++ Q +S+ N ++
Sbjct: 733 PQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKD 792
Query: 754 AFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEV 813
LT KA A L ILG SWV G+ + A V Y+F +NSLQG FIFL HCLLN +V
Sbjct: 793 TRLLTFKAFAQLF-ILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQV 851
Query: 814 RAAFKHKTKVWSLTSSSARTS 834
R +K + SS ++TS
Sbjct: 852 REEYKRWITGKTKPSSQSQTS 872
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 198 bits (504), Expect = 2e-50
Identities = 129/406 (31%), Positives = 213/406 (52%), Gaps = 37/406 (9%)
Query: 456 LFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF 515
++ S ++S + P +N+S S +T+ QH + T S+ +VF C +
Sbjct: 263 VYLNSQVVSAAIGP----KRNVSLSKSVTLTF-------QHVKMTPSTKKVF--CVYWKS 309
Query: 516 SSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCS 575
+ WS GC L N ++++C C+HL++FA+LM + E L+ I+YVG S
Sbjct: 310 TGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQE----EDPVLTVITYVGLS 365
Query: 576 LSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISF-RLEPGTTPCQV 634
+S+LCL+ +TF + + IRN +H LS + +A +L L+ R EP C +
Sbjct: 366 VSLLCLLLAALTFLLCKA---IRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVL-CSI 421
Query: 635 MAVLLHYFFLSAFAWMLVEGLHLY----SMVIKVFGSEDSKHRY-YYGMGWGFPLLICII 689
+A LHY +L+AF WML+EG+HL+ ++ + + S + ++ + +G+G P + I
Sbjct: 422 IAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAI 481
Query: 690 SLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVIS-QISADNYKI 748
S + YGT++ CWL L G +W+F+ P + N+ + I V ++ ++S+ N ++
Sbjct: 482 SAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEV 541
Query: 749 HGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCL 808
+ L KA A L ILG +W G+L V A V Y+F +NSLQG FIFL +CL
Sbjct: 542 STIQNTRMLAFKATAQLF-ILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCL 600
Query: 809 LNSEV--------RAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNG 846
L+ +V R K K++ + T SS ++KP D+ G
Sbjct: 601 LSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPG 646
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 194 bits (494), Expect = 2e-49
Identities = 106/319 (33%), Positives = 171/319 (53%), Gaps = 11/319 (3%)
Query: 502 SSNRVFVYCAFLD---FSSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLEL 558
++NR C D + GVW+ C L N +++ CRC+ F +LM P E
Sbjct: 2472 TANRSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRER 2531
Query: 559 ARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVL 618
G L+ ++V ++SV LV +T A+L S+ ++++ IHAN++ A+ VA++L
Sbjct: 2532 LEGDLELLAVFTHVVVAVSVAALV---LTAAILLSLRSLKSNVRGIHANVAAALGVAELL 2588
Query: 619 LLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGM 678
L+ C +A+LLHYFFLS FAW+ V+GLHLY M ++ + R+Y+ +
Sbjct: 2589 FLLGIHRTHNQLVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHAL 2648
Query: 679 GWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVI 738
GWG P ++ +++ + YG + CW+S+ IW+F P + VIV+N + + R
Sbjct: 2649 GWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMFLLAARTS 2708
Query: 739 SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQ 798
K LT ++ +LL ++ SW+FG+LAVN + F Y+ A L LQ
Sbjct: 2709 CSTGQREAK-----KTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGLCGLQ 2763
Query: 799 GLFIFLFHCLLNSEVRAAF 817
GL + L C+LN++ RAA+
Sbjct: 2764 GLAVLLLFCVLNADARAAW 2782
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 191 bits (486), Expect = 2e-48
Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%)
Query: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568
CAF S G W+ GC + + C+C+HL++FAILM +E L+
Sbjct: 446 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 500
Query: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628
I+ VG +LS+ CL+ ++TF + V I+ R IH +L + V + L E G
Sbjct: 501 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 557
Query: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C+++A LLHY FL+AF WM +EGL LY +V++VF + R+ +G+G PLLI
Sbjct: 558 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 617
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742
+S + YG CWL G +W+F+ P F+I+ N I + +T+ S+I+
Sbjct: 618 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 677
Query: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802
D K+ A LT A+A L +LG +WVFG+ + ++V Y+F LN LQG F+
Sbjct: 678 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 733
Query: 803 FLFHCLLNSEVRAAFK 818
+L HCLLN +VR ++
Sbjct: 734 YLLHCLLNKKVREEYR 749
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 191 bits (486), Expect = 2e-48
Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%)
Query: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568
CAF S G W+ GC + + C+C+HL++FAILM +E L+
Sbjct: 402 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 456
Query: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628
I+ VG +LS+ CL+ ++TF + V I+ R IH +L + V + L E G
Sbjct: 457 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 513
Query: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C+++A LLHY FL+AF WM +EGL LY +V++VF + R+ +G+G PLLI
Sbjct: 514 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 573
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742
+S + YG CWL G +W+F+ P F+I+ N I + +T+ S+I+
Sbjct: 574 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 633
Query: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802
D K+ A LT A+A L +LG +WVFG+ + ++V Y+F LN LQG F+
Sbjct: 634 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 689
Query: 803 FLFHCLLNSEVRAAFK 818
+L HCLLN +VR ++
Sbjct: 690 YLLHCLLNKKVREEYR 705
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 191 bits (486), Expect = 2e-48
Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%)
Query: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568
CAF S G W+ GC + + C+C+HL++FAILM +E L+
Sbjct: 495 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 549
Query: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628
I+ VG +LS+ CL+ ++TF + V I+ R IH +L + V + L E G
Sbjct: 550 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 606
Query: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C+++A LLHY FL+AF WM +EGL LY +V++VF + R+ +G+G PLLI
Sbjct: 607 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 666
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742
+S + YG CWL G +W+F+ P F+I+ N I + +T+ S+I+
Sbjct: 667 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 726
Query: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802
D K+ A LT A+A L +LG +WVFG+ + ++V Y+F LN LQG F+
Sbjct: 727 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 782
Query: 803 FLFHCLLNSEVRAAFK 818
+L HCLLN +VR ++
Sbjct: 783 YLLHCLLNKKVREEYR 798
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 189 bits (481), Expect = 7e-48
Identities = 105/312 (33%), Positives = 170/312 (54%), Gaps = 12/312 (3%)
Query: 510 CAFLDFS---SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVAL 566
C F + S SG G WS GC + N ++ C+C H+T+FA+LM V E G + L
Sbjct: 2319 CVFWNHSILVSGTGGWSARGCEVVFRNESHVSCQCNHMTSFAVLMDVSRRE--NGEILPL 2376
Query: 567 SSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLE 626
+++YV ++ L A L+TF L+ + +R+ ++ I NL+ A+ +AQ++ L+
Sbjct: 2377 KTLTYVALGVT---LAALLLTFFFLTLLRILRSNQHGIRRNLTAALGLAQLVFLLGINQA 2433
Query: 627 PGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686
C V+A+LLH+ +L F+W L+E LHLY + +V R+YY +GWG P I
Sbjct: 2434 DLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVRDVNTGPMRFYYMLGWGVPAFI 2493
Query: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNY 746
+++ + YG + CWLS+ IW+F P F + +++ + I R +
Sbjct: 2494 TGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAGPVAFAVSMSVFLYILAARASCAAQRQGF 2553
Query: 747 KIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFH 806
+ G S + + AVLL +L +W+ +L+VN ++F Y+FAT N +QG FIFL +
Sbjct: 2554 EKKGPVSGLQ---PSFAVLL-LLSATWLLALLSVNSDTLLFHYLFATCNCIQGPFIFLSY 2609
Query: 807 CLLNSEVRAAFK 818
+L+ EVR A K
Sbjct: 2610 VVLSKEVRKALK 2621
>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
Length = 963
Score = 184 bits (466), Expect = 4e-46
Identities = 104/307 (33%), Positives = 160/307 (52%), Gaps = 13/307 (4%)
Query: 520 GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVL 579
G W+ GC++ L + C C H T+FAIL+Q+ ++ + L ++S+VGC +S
Sbjct: 612 GAWATTGCSVAALYLDSTACFCNHSTSFAILLQIYEVQRGPEEESLLRTLSFVGCGVSFC 671
Query: 580 CLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLL 639
L T + F V +++R +H NL+F++ A+ L+ S + C + V +
Sbjct: 672 ALTTTFLLFLV---AGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKANEVACVAVTVAM 728
Query: 640 HYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYG 699
H+ FL AF+WMLVEGL L+ V+ V R Y+ GWG P+ I ++L+ Y
Sbjct: 729 HFLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGMRLYHATGWGVPVGIVAVTLAMLPHDYV 788
Query: 700 TSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRV-ISQISADNYKIHGDP------ 752
+CWL++ + AIWAFV P LFV+ N IL V + +S + P
Sbjct: 789 APGHCWLNVHTNAIWAFVGPVLFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQI 848
Query: 753 -SAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNS 811
+ T K V VLLP+LG +W+ G+L + + Y LNS+QGL+IFL + N
Sbjct: 849 WTQIWATVKPVLVLLPVLGLTWLAGILV--HLSPAWAYAAVGLNSIQGLYIFLVYAACNE 906
Query: 812 EVRAAFK 818
EVR+A +
Sbjct: 907 EVRSALQ 913
Score = 32.3 bits (72), Expect = 2.0
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 140 GGRGSVELYTRDNSMTWEASFSPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSR 199
GG L R + A+F G W HV TW+ + G + + G +
Sbjct: 182 GGVVRAALVVRGQHAPFLAAFRADGR-WHHVCATWEQRGGRWALFSDGRRRAGARGLGAG 240
Query: 200 DYGESNVNLVIGSEQDQ------AKCYENGAFDEFIIWERALTPDEI 240
S LV+G +QD + +G +F +W RAL+P ++
Sbjct: 241 HPVPSGGILVLGQDQDSLGGGFSVRHALSGNLTDFHLWARALSPAQL 287
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 179 bits (453), Expect = 1e-44
Identities = 151/552 (27%), Positives = 257/552 (46%), Gaps = 59/552 (10%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 297 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 356
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHA--WSTVVGLLYHSM 431
+ ++ V K + ++V Q+ +Q+ + +VVGL+
Sbjct: 357 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSGDPGPSVVGLV---- 405
Query: 432 HYYLNNIWPAHTKIAEA---MHHQDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLK 488
+I +AEA + + +L +H L+ P LS +I+ L
Sbjct: 406 -----SIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSD------VISAFLS 454
Query: 489 HRLTRKQHSEATNSSN------RVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRC 541
+ T+ S T + + R V C F + +G G W+ GC+ T ++CRC
Sbjct: 455 NNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 514
Query: 542 THLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQR 601
THL++FA+LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N
Sbjct: 515 THLSSFAVLMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTS 568
Query: 602 YHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM- 660
+H LS + +A +L L++ C ++A LHY +L+ WML+E L+L+
Sbjct: 569 TSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTA 628
Query: 661 ----VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAF 716
V+ + + +G+G P + IS + YGT + CWL G IW F
Sbjct: 629 RNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGF 688
Query: 717 VAPALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVF 775
+ P + VN+ + + ++ +++S+ N ++ + L KA A L ILG +W
Sbjct: 689 LGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCL 747
Query: 776 GVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT 827
G+L V A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T
Sbjct: 748 GILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHT 807
Query: 828 -SSSARTSNAKP 838
SSSA+ +KP
Sbjct: 808 LSSSAKADTSKP 819
>gi|23397687 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform d [Homo sapiens]
Length = 681
Score = 179 bits (453), Expect = 1e-44
Identities = 151/552 (27%), Positives = 257/552 (46%), Gaps = 59/552 (10%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 155 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 214
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHA--WSTVVGLLYHSM 431
+ ++ V K + ++V Q+ +Q+ + +VVGL+
Sbjct: 215 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSGDPGPSVVGLV---- 263
Query: 432 HYYLNNIWPAHTKIAEA---MHHQDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLK 488
+I +AEA + + +L +H L+ P LS +I+ L
Sbjct: 264 -----SIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSD------VISAFLS 312
Query: 489 HRLTRKQHSEATNSSN------RVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRC 541
+ T+ S T + + R V C F + +G G W+ GC+ T ++CRC
Sbjct: 313 NNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 372
Query: 542 THLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQR 601
THL++FA+LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N
Sbjct: 373 THLSSFAVLMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTS 426
Query: 602 YHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM- 660
+H LS + +A +L L++ C ++A LHY +L+ WML+E L+L+
Sbjct: 427 TSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTA 486
Query: 661 ----VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAF 716
V+ + + +G+G P + IS + YGT + CWL G IW F
Sbjct: 487 RNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGF 546
Query: 717 VAPALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVF 775
+ P + VN+ + + ++ +++S+ N ++ + L KA A L ILG +W
Sbjct: 547 LGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCL 605
Query: 776 GVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT 827
G+L V A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T
Sbjct: 606 GILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHT 665
Query: 828 -SSSARTSNAKP 838
SSSA+ +KP
Sbjct: 666 LSSSAKADTSKP 677
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 179 bits (453), Expect = 1e-44
Identities = 151/552 (27%), Positives = 257/552 (46%), Gaps = 59/552 (10%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 204 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 263
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHA--WSTVVGLLYHSM 431
+ ++ V K + ++V Q+ +Q+ + +VVGL+
Sbjct: 264 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSGDPGPSVVGLV---- 312
Query: 432 HYYLNNIWPAHTKIAEA---MHHQDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLK 488
+I +AEA + + +L +H L+ P LS +I+ L
Sbjct: 313 -----SIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSD------VISAFLS 361
Query: 489 HRLTRKQHSEATNSSN------RVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRC 541
+ T+ S T + + R V C F + +G G W+ GC+ T ++CRC
Sbjct: 362 NNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 421
Query: 542 THLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQR 601
THL++FA+LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N
Sbjct: 422 THLSSFAVLMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTS 475
Query: 602 YHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM- 660
+H LS + +A +L L++ C ++A LHY +L+ WML+E L+L+
Sbjct: 476 TSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTA 535
Query: 661 ----VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAF 716
V+ + + +G+G P + IS + YGT + CWL G IW F
Sbjct: 536 RNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGF 595
Query: 717 VAPALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVF 775
+ P + VN+ + + ++ +++S+ N ++ + L KA A L ILG +W
Sbjct: 596 LGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCL 654
Query: 776 GVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT 827
G+L V A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T
Sbjct: 655 GILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHT 714
Query: 828 -SSSARTSNAKP 838
SSSA+ +KP
Sbjct: 715 LSSSAKADTSKP 726
>gi|23397683 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform b [Homo sapiens]
Length = 774
Score = 179 bits (453), Expect = 1e-44
Identities = 151/552 (27%), Positives = 257/552 (46%), Gaps = 59/552 (10%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 248 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 307
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHA--WSTVVGLLYHSM 431
+ ++ V K + ++V Q+ +Q+ + +VVGL+
Sbjct: 308 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSGDPGPSVVGLV---- 356
Query: 432 HYYLNNIWPAHTKIAEA---MHHQDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLK 488
+I +AEA + + +L +H L+ P LS +I+ L
Sbjct: 357 -----SIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSD------VISAFLS 405
Query: 489 HRLTRKQHSEATNSSN------RVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRC 541
+ T+ S T + + R V C F + +G G W+ GC+ T ++CRC
Sbjct: 406 NNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 465
Query: 542 THLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQR 601
THL++FA+LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N
Sbjct: 466 THLSSFAVLMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTS 519
Query: 602 YHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM- 660
+H LS + +A +L L++ C ++A LHY +L+ WML+E L+L+
Sbjct: 520 TSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTA 579
Query: 661 ----VIKVFGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAF 716
V+ + + +G+G P + IS + YGT + CWL G IW F
Sbjct: 580 RNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGF 639
Query: 717 VAPALFVIVVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVF 775
+ P + VN+ + + ++ +++S+ N ++ + L KA A L ILG +W
Sbjct: 640 LGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCL 698
Query: 776 GVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT 827
G+L V A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T
Sbjct: 699 GILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHT 758
Query: 828 -SSSARTSNAKP 838
SSSA+ +KP
Sbjct: 759 LSSSAKADTSKP 770
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 177 bits (450), Expect = 3e-44
Identities = 149/544 (27%), Positives = 248/544 (45%), Gaps = 54/544 (9%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 204 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 263
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAWSTVVGLLYHSMHY 433
+ ++ V K + ++V Q+ +Q+ + +G L
Sbjct: 264 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSG-DPGMGKLLAEAPL 315
Query: 434 YLNNIWPAHTKIAEAMHH---QDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHR 490
L P + H QD S +IS +S T QNLS T +
Sbjct: 316 VLE---PEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDT--QNLSSPVTFTFSHRSV 370
Query: 491 LTRKQHSEATNSSNRVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAI 549
+ R++ V C F + +G G W+ GC+ T ++CRCTHL++FA+
Sbjct: 371 IPRQK------------VLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAV 418
Query: 550 LMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLS 609
LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N +H LS
Sbjct: 419 LMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTSTSLHLQLS 472
Query: 610 FAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM-----VIKV 664
+ +A +L L++ C ++A LHY +L+ WML+E L+L+ V+
Sbjct: 473 LCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 532
Query: 665 FGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVI 724
+ + +G+G P + IS + YGT + CWL G IW F+ P +
Sbjct: 533 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIF 592
Query: 725 VVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGC 783
VN+ + + ++ +++S+ N ++ + L KA A L ILG +W G+L V
Sbjct: 593 SVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGPA 651
Query: 784 AVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT-SSSARTS 834
A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T SSSA+
Sbjct: 652 ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKAD 711
Query: 835 NAKP 838
+KP
Sbjct: 712 TSKP 715
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 177 bits (450), Expect = 3e-44
Identities = 149/544 (27%), Positives = 248/544 (45%), Gaps = 54/544 (9%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 248 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 307
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAWSTVVGLLYHSMHY 433
+ ++ V K + ++V Q+ +Q+ + +G L
Sbjct: 308 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSG-DPGMGKLLAEAPL 359
Query: 434 YLNNIWPAHTKIAEAMHH---QDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHR 490
L P + H QD S +IS +S T QNLS T +
Sbjct: 360 VLE---PEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDT--QNLSSPVTFTFSHRSV 414
Query: 491 LTRKQHSEATNSSNRVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAI 549
+ R++ V C F + +G G W+ GC+ T ++CRCTHL++FA+
Sbjct: 415 IPRQK------------VLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAV 462
Query: 550 LMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLS 609
LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N +H LS
Sbjct: 463 LMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTSTSLHLQLS 516
Query: 610 FAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM-----VIKV 664
+ +A +L L++ C ++A LHY +L+ WML+E L+L+ V+
Sbjct: 517 LCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 576
Query: 665 FGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVI 724
+ + +G+G P + IS + YGT + CWL G IW F+ P +
Sbjct: 577 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIF 636
Query: 725 VVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGC 783
VN+ + + ++ +++S+ N ++ + L KA A L ILG +W G+L V
Sbjct: 637 SVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGPA 695
Query: 784 AVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT-SSSARTS 834
A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T SSSA+
Sbjct: 696 ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKAD 755
Query: 835 NAKP 838
+KP
Sbjct: 756 TSKP 759
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 177 bits (450), Expect = 3e-44
Identities = 149/544 (27%), Positives = 248/544 (45%), Gaps = 54/544 (9%)
Query: 317 ALNLTKTFLKAVGEILLLPG---WIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVT 373
A N ++ L+A+ E+L PG + + V L+D ++ V+ +S NL +
Sbjct: 297 ANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFS 356
Query: 374 VEGSSAMAEFSVAKILPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAWSTVVGLLYHSMHY 433
+ ++ V K + ++V Q+ +Q+ + +G L
Sbjct: 357 YPAGTELS-LEVQKQVDRSVTLRQ------NQAVMQLDWNQAQKSG-DPGMGKLLAEAPL 408
Query: 434 YLNNIWPAHTKIAEAMHH---QDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHR 490
L P + H QD S +IS +S T QNLS T +
Sbjct: 409 VLE---PEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDT--QNLSSPVTFTFSHRSV 463
Query: 491 LTRKQHSEATNSSNRVFVYCAFLDFS-SGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAI 549
+ R++ V C F + +G G W+ GC+ T ++CRCTHL++FA+
Sbjct: 464 IPRQK------------VLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAV 511
Query: 550 LMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLS 609
LM ++ L+ I+Y+G S+S+LCL+ +TF + + I+N +H LS
Sbjct: 512 LMAHYDVQ---EEDPVLTVITYMGLSVSLLCLLLAALTFLLCKA---IQNTSTSLHLQLS 565
Query: 610 FAVLVAQVLLLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSM-----VIKV 664
+ +A +L L++ C ++A LHY +L+ WML+E L+L+ V+
Sbjct: 566 LCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 625
Query: 665 FGSEDSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVI 724
+ + +G+G P + IS + YGT + CWL G IW F+ P +
Sbjct: 626 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIF 685
Query: 725 VVNIGILIAVTRVI-SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGC 783
VN+ + + ++ +++S+ N ++ + L KA A L ILG +W G+L V
Sbjct: 686 SVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGPA 744
Query: 784 AVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAF--------KHKTKVWSLT-SSSARTS 834
A V Y+F +NSLQG+FIFL +CLL+ +VR + K KT+ T SSSA+
Sbjct: 745 ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKAD 804
Query: 835 NAKP 838
+KP
Sbjct: 805 TSKP 808
>gi|148719671 G-protein coupled receptor 116 [Homo sapiens]
Length = 1346
Score = 165 bits (417), Expect = 2e-40
Identities = 118/379 (31%), Positives = 187/379 (49%), Gaps = 19/379 (5%)
Query: 476 NLSGSPLITVHLKHRLTRKQHSEAT---NSSNRVFVYCAFLDF--SSGEGVWSNHGCALT 530
N + S ++T + H T T NS + C F +F ++ G W + GC +
Sbjct: 917 NFAESLVMTTTVSHNTTMPFRISMTFKNNSPSGGETKCVFWNFRLANNTGGWDSSGCYVE 976
Query: 531 RGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAV 590
G+ C C HLT+F+ILM + + + L ISYVG S+L L A LV AV
Sbjct: 977 EGDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVGVGFSILSLAACLVVEAV 1036
Query: 591 LSSVSTIRNQRYHIHA---NLSFAVLVAQVLLLISFRLEPGT-----TPCQVMAVLLHYF 642
+ T Y H N++ ++LVA ++ ++ T C +H+F
Sbjct: 1037 VWKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFF 1096
Query: 643 FLSAFAWMLVEGLHLYSMVIKVFG--SEDSKHRYYYGMGWGFPLLICIISLSFAM--DSY 698
+LS F WML GL L+ ++ + S ++ + +G+G PL I +I+L + Y
Sbjct: 1097 YLSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVY 1156
Query: 699 GTSNNCWLSLA-SGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNYKIHGDPSAFKL 757
N CWL+ + A+ AF PAL ++VVNI I I V I + S + + S+
Sbjct: 1157 TRKNVCWLNWEDTKALLAFAIPALIIVVVNITITIVVITKILRPSIGDKPCKQEKSSLFQ 1216
Query: 758 TAKAVAVLLPILGTSWVFGVLAV-NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAA 816
+K++ VL P+LG +W FG+ V G +VF +FA LN QGLFI LF CL + +V+ A
Sbjct: 1217 ISKSIGVLTPLLGLTWGFGLTTVFPGTNLVFHIIFAILNVFQGLFILLFGCLWDLKVQEA 1276
Query: 817 FKHKTKVWSLTSSSARTSN 835
+K + +S +++++
Sbjct: 1277 LLNKFSLSRWSSQHSKSTS 1295
>gi|148719673 G-protein coupled receptor 116 [Homo sapiens]
Length = 1346
Score = 165 bits (417), Expect = 2e-40
Identities = 118/379 (31%), Positives = 187/379 (49%), Gaps = 19/379 (5%)
Query: 476 NLSGSPLITVHLKHRLTRKQHSEAT---NSSNRVFVYCAFLDF--SSGEGVWSNHGCALT 530
N + S ++T + H T T NS + C F +F ++ G W + GC +
Sbjct: 917 NFAESLVMTTTVSHNTTMPFRISMTFKNNSPSGGETKCVFWNFRLANNTGGWDSSGCYVE 976
Query: 531 RGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAV 590
G+ C C HLT+F+ILM + + + L ISYVG S+L L A LV AV
Sbjct: 977 EGDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVGVGFSILSLAACLVVEAV 1036
Query: 591 LSSVSTIRNQRYHIHA---NLSFAVLVAQVLLLISFRLEPGT-----TPCQVMAVLLHYF 642
+ T Y H N++ ++LVA ++ ++ T C +H+F
Sbjct: 1037 VWKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFF 1096
Query: 643 FLSAFAWMLVEGLHLYSMVIKVFG--SEDSKHRYYYGMGWGFPLLICIISLSFAM--DSY 698
+LS F WML GL L+ ++ + S ++ + +G+G PL I +I+L + Y
Sbjct: 1097 YLSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVY 1156
Query: 699 GTSNNCWLSLA-SGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNYKIHGDPSAFKL 757
N CWL+ + A+ AF PAL ++VVNI I I V I + S + + S+
Sbjct: 1157 TRKNVCWLNWEDTKALLAFAIPALIIVVVNITITIVVITKILRPSIGDKPCKQEKSSLFQ 1216
Query: 758 TAKAVAVLLPILGTSWVFGVLAV-NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAA 816
+K++ VL P+LG +W FG+ V G +VF +FA LN QGLFI LF CL + +V+ A
Sbjct: 1217 ISKSIGVLTPLLGLTWGFGLTTVFPGTNLVFHIIFAILNVFQGLFILLFGCLWDLKVQEA 1276
Query: 817 FKHKTKVWSLTSSSARTSN 835
+K + +S +++++
Sbjct: 1277 LLNKFSLSRWSSQHSKSTS 1295
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 159 bits (401), Expect = 1e-38
Identities = 102/354 (28%), Positives = 173/354 (48%), Gaps = 32/354 (9%)
Query: 483 ITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF--SSGEGVWSNHGCALTRGNLTYSVCR 540
+TV LKH S + + V C F D + G G WS++GC++ L ++C
Sbjct: 530 VTVTLKH---------INPSQDELTVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICT 580
Query: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
C+HLT+F +L+ + + +AL+ I+Y+GC LS + L TLVT+ + R+
Sbjct: 581 CSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIR--RDY 638
Query: 601 RYHIHANLSFAVLVAQVLLLIS--FRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLY 658
I L A+L+ ++ L+ L C +AV LHYF L +F WM +E H+Y
Sbjct: 639 PSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMY 698
Query: 659 SMVIKVFGSEDSKHRYYYG-MGWGFPLLICIISLSFAMDSYGTSNN-----------CWL 706
++KVF + K+ + +GWG P ++ I L+ + D+YG + CW+
Sbjct: 699 LALVKVFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI 758
Query: 707 SLASGAIWAFVAPALFVIV--VNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAV 764
+ + A++ F ++ +N+ + I V + +I ++ +++A
Sbjct: 759 N--NNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKK-QLGAQRKTSIQDLRSIAG 815
Query: 765 LLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818
L +LG +W F A V F Y+FA N+LQG FIF+F+C+ VR ++
Sbjct: 816 LTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWR 869
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 159 bits (401), Expect = 1e-38
Identities = 102/354 (28%), Positives = 173/354 (48%), Gaps = 32/354 (9%)
Query: 483 ITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF--SSGEGVWSNHGCALTRGNLTYSVCR 540
+TV LKH S + + V C F D + G G WS++GC++ L ++C
Sbjct: 538 VTVTLKH---------INPSQDELTVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICT 588
Query: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
C+HLT+F +L+ + + +AL+ I+Y+GC LS + L TLVT+ + R+
Sbjct: 589 CSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIR--RDY 646
Query: 601 RYHIHANLSFAVLVAQVLLLIS--FRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLY 658
I L A+L+ ++ L+ L C +AV LHYF L +F WM +E H+Y
Sbjct: 647 PSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMY 706
Query: 659 SMVIKVFGSEDSKHRYYYG-MGWGFPLLICIISLSFAMDSYGTSNN-----------CWL 706
++KVF + K+ + +GWG P ++ I L+ + D+YG + CW+
Sbjct: 707 LALVKVFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI 766
Query: 707 SLASGAIWAFVAPALFVIV--VNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAV 764
+ + A++ F ++ +N+ + I V + +I ++ +++A
Sbjct: 767 N--NNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKK-QLGAQRKTSIQDLRSIAG 823
Query: 765 LLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818
L +LG +W F A V F Y+FA N+LQG FIF+F+C+ VR ++
Sbjct: 824 LTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWR 877
>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
Length = 1017
Score = 159 bits (401), Expect = 1e-38
Identities = 102/354 (28%), Positives = 173/354 (48%), Gaps = 32/354 (9%)
Query: 483 ITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF--SSGEGVWSNHGCALTRGNLTYSVCR 540
+TV LKH S + + V C F D + G G WS++GC++ L ++C
Sbjct: 552 VTVTLKH---------INPSQDELTVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICT 602
Query: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
C+HLT+F +L+ + + +AL+ I+Y+GC LS + L TLVT+ + R+
Sbjct: 603 CSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIR--RDY 660
Query: 601 RYHIHANLSFAVLVAQVLLLIS--FRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLY 658
I L A+L+ ++ L+ L C +AV LHYF L +F WM +E H+Y
Sbjct: 661 PSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMY 720
Query: 659 SMVIKVFGSEDSKHRYYYG-MGWGFPLLICIISLSFAMDSYGTSNN-----------CWL 706
++KVF + K+ + +GWG P ++ I L+ + D+YG + CW+
Sbjct: 721 LALVKVFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI 780
Query: 707 SLASGAIWAFVAPALFVIV--VNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAV 764
+ + A++ F ++ +N+ + I V + +I ++ +++A
Sbjct: 781 N--NNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKK-QLGAQRKTSIQDLRSIAG 837
Query: 765 LLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818
L +LG +W F A V F Y+FA N+LQG FIF+F+C+ VR ++
Sbjct: 838 LTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWR 891
>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
Length = 1014
Score = 159 bits (401), Expect = 1e-38
Identities = 102/354 (28%), Positives = 173/354 (48%), Gaps = 32/354 (9%)
Query: 483 ITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF--SSGEGVWSNHGCALTRGNLTYSVCR 540
+TV LKH S + + V C F D + G G WS++GC++ L ++C
Sbjct: 549 VTVTLKH---------INPSQDELTVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICT 599
Query: 541 CTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQ 600
C+HLT+F +L+ + + +AL+ I+Y+GC LS + L TLVT+ + R+
Sbjct: 600 CSHLTSFGVLLDLSRTSVLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIR--RDY 657
Query: 601 RYHIHANLSFAVLVAQVLLLIS--FRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLY 658
I L A+L+ ++ L+ L C +AV LHYF L +F WM +E H+Y
Sbjct: 658 PSKILIQLCAALLLLNLVFLLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMY 717
Query: 659 SMVIKVFGSEDSKHRYYYG-MGWGFPLLICIISLSFAMDSYGTSNN-----------CWL 706
++KVF + K+ + +GWG P ++ I L+ + D+YG + CW+
Sbjct: 718 LALVKVFNTYIRKYILKFCIVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWI 777
Query: 707 SLASGAIWAFVAPALFVIV--VNIGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAV 764
+ + A++ F ++ +N+ + I V + +I ++ +++A
Sbjct: 778 N--NNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKK-QLGAQRKTSIQDLRSIAG 834
Query: 765 LLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818
L +LG +W F A V F Y+FA N+LQG FIF+F+C+ VR ++
Sbjct: 835 LTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWR 888
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 158 bits (400), Expect = 2e-38
Identities = 110/371 (29%), Positives = 182/371 (49%), Gaps = 37/371 (9%)
Query: 459 TSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSG 518
T++++S +S + QNL+ +IT+ QH + +V +CAF DF +
Sbjct: 2646 TTYVVSASISDDMFI-QNLADPVVITL---------QHIGGNQNYGQV--HCAFWDFENN 2693
Query: 519 EGV--WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSL 576
G+ W++ GC + N+ Y++C+C HLT+F +LM + + ++ L+ I+Y GC +
Sbjct: 2694 NGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGI 2753
Query: 577 SVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLE--PGTTPCQV 634
S + L +VT+ + ++ I NL A+L+ ++ LI+ L C
Sbjct: 2754 SSIFLGVAVVTYIAFHKLR--KDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCIT 2811
Query: 635 MAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGM-GWGFPLLICIISLSF 693
AV LHYF L +F WM +E +H+Y ++KVF + + + GWG P ++ I++S
Sbjct: 2812 AAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSV 2871
Query: 694 AMDSYGTSNN----CWLSLASGAIWAFVAPALFVIVVNIG----ILIAVTRVISQISADN 745
D YGT + CW+ S + VA + ++N+ +L+ + V SQI
Sbjct: 2872 KKDLYGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTR 2931
Query: 746 YK--IHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIF 803
K +H LT +LG +W F A F Y+FA N+LQG FIF
Sbjct: 2932 RKMILHDLKGTMSLTF--------LLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIF 2983
Query: 804 LFHCLLNSEVR 814
+FHC++ VR
Sbjct: 2984 VFHCVMKESVR 2994
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 155 bits (391), Expect = 2e-37
Identities = 119/402 (29%), Positives = 182/402 (45%), Gaps = 61/402 (15%)
Query: 456 LFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF 515
L TS ++++ V PP PLITV L + + + +CA D+
Sbjct: 835 LAVTSRVMTVTVRPPT----QPPAEPLITVELSYII-----------NGTTDPHCASWDY 879
Query: 516 SSGE---GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQV---VPLELARGHQVALSSI 569
S + G W C ++ C+C HL+ FA+L Q + LELA V L
Sbjct: 880 SRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPL--- 936
Query: 570 SYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGT 629
+GC++S + L+ L +A I+++R I N ++L + +L+L+
Sbjct: 937 -VIGCAVSCMALLTLLAIYAAFWRF--IKSERSIILLNFCLSILASNILILVGQSRVLSK 993
Query: 630 TPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICII 689
C + A LH+FFLS+F W+L E Y VI + + R+ +GWG P L+ +
Sbjct: 994 GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLC-LGWGLPALVVAV 1052
Query: 690 SLSFAMDS-YGTSNNCWLSLASGAIWAFVAPALFVIVVN--IGILIAVTRVISQISADNY 746
S+ F YGTS+ CWLSL G ++AFV PA +++VN IGI++ + +D
Sbjct: 1053 SVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKS 1112
Query: 747 K--------------------IHGDPSAFKLTAKA---------VAVLLPILGTSWVFGV 777
K PS +A A V+LP+L +W+ V
Sbjct: 1113 KKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAV 1172
Query: 778 LAV-NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818
LA+ + +V+FQ +FA NS QG I HC L EV+ K
Sbjct: 1173 LAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVK 1214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,076,842
Number of Sequences: 37866
Number of extensions: 1436991
Number of successful extensions: 3497
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3145
Number of HSP's gapped (non-prelim): 159
length of query: 874
length of database: 18,247,518
effective HSP length: 111
effective length of query: 763
effective length of database: 14,044,392
effective search space: 10715871096
effective search space used: 10715871096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.