Guide to the Human Genome
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Search of human proteins with 45387931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45387931 hypothetical protein LOC167555 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45387931 hypothetical protein LOC167555 [Homo sapiens]             571   e-163
gi|194097418 hypothetical protein LOC338094 [Homo sapiens]            219   2e-57
gi|238908501 sciellin isoform 3 [Homo sapiens]                         30   1.8  
gi|238908499 sciellin isoform 1 [Homo sapiens]                         30   1.8  
gi|238908497 sciellin isoform 2 [Homo sapiens]                         30   1.8  
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid...    30   1.8  
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            30   2.3  
gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]      28   8.7  
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho...    28   8.7  
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho...    28   8.7  
gi|33188445 microfilament and actin filament cross-linker protei...    28   8.7  

>gi|45387931 hypothetical protein LOC167555 [Homo sapiens]
          Length = 276

 Score =  571 bits (1472), Expect = e-163
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADV 60
           MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADV
Sbjct: 1   MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADV 60

Query: 61  LLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENV 120
           LLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENV
Sbjct: 61  LLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENV 120

Query: 121 KRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGY 180
           KRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGY
Sbjct: 121 KRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGY 180

Query: 181 SWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVE 240
           SWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVE
Sbjct: 181 SWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVE 240

Query: 241 DLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL 276
           DLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL
Sbjct: 241 DLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL 276


>gi|194097418 hypothetical protein LOC338094 [Homo sapiens]
          Length = 585

 Score =  219 bits (559), Expect = 2e-57
 Identities = 121/261 (46%), Positives = 160/261 (61%), Gaps = 6/261 (2%)

Query: 14  NILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADVLLPSDGS--EHSQ 71
           ++L+Y L   QI+  D  E+TWYHAAN K     AL S   ++EADV +   G+  E   
Sbjct: 51  DMLDYLLSLGQISRRDALEVTWYHAANSKKAMTAALNSNITVLEADVNVEGLGTANETGV 110

Query: 72  PIMAHPPETNSDNTLQEWLTEVM-KSNKGIKLDFKSLAVVEPSMMLLENVKRH--LKRPV 128
           PIMAHPP   SDNTL++WL  V+  S KGIKLDFK++  V PS+ LL  +     ++RP+
Sbjct: 111 PIMAHPPTIYSDNTLEQWLDAVLGSSQKGIKLDFKNIKAVGPSLDLLRQLTEEGKVRRPI 170

Query: 129 WINADILPGPNGN-SKVIDAKPFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYSWTMVKE 187
           WINADIL GPN   S  ++A  FL  V   +P  T S GWTT +     N  Y+  MV++
Sbjct: 171 WINADILKGPNMLISTEVNATQFLALVQEKYPKATLSPGWTTFYMSTSPNRTYTQAMVEK 230

Query: 188 MEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVEDLLYIRD 247
           M  +   + Q VTFPVR+++VR +     WLL +S RYSLT+W   +D  SVEDLLY+RD
Sbjct: 231 MHELVGGVPQRVTFPVRSSMVRAAWPHFSWLLSQSERYSLTLWQAASDPMSVEDLLYVRD 290

Query: 248 HFDKKQVFYDILEPQNHEFKQ 268
           +    QV+YDI EP   +FKQ
Sbjct: 291 NTAVHQVYYDIFEPLLSQFKQ 311



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 69/259 (26%), Positives = 109/259 (42%), Gaps = 19/259 (7%)

Query: 24  QITAEDGAEITWY--HAANHKAQTNEALKSTAHMIEADVLLPSDGSEHSQPIMAHPPETN 81
           Q+  +DG  + W               L  T  MI  +  L    +E+  PI+ H P  N
Sbjct: 333 QLPGDDGLNVEWLVPDVQGSGKTATMTLPDTEGMILLNTGLEGTVAENPVPIV-HTPSGN 391

Query: 82  S---DNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENVKRH--LKRPVWINADILP 136
               ++ LQ+  T     + GI L     A + PS+ LL  +     L  PVW+ A I  
Sbjct: 392 ILTLESCLQQLATH--PGHWGIHLQIAEPAALRPSLALLARLSSLGLLHWPVWVGAKISH 449

Query: 137 GPNGNSKVIDAKPFLDTVTSFFPDVTFSLGWTTGWHPEKV-NEGYSWTMVKEMEYICNEL 195
           G       +  +  L  V   FP VT + GW     PE+V   GY   ++ +M  +C  L
Sbjct: 450 GSFSVPGHVAGRELLTAVAEVFPHVTVAPGW-----PEEVLGSGYREQLLTDMLELCQGL 504

Query: 196 SQPVTFPVRAALVRQSCSQLLW-LLKKSNRYSLTIW--TGKNDNYSVEDLLYIRDHFDKK 252
            QPV+F ++A L+  S +  +  LL  S R ++T+       D  SV   L      D+ 
Sbjct: 505 WQPVSFQMQAMLLGHSTAGAIGRLLASSPRATVTVEHNPAGGDYASVRTALLAARAVDRT 564

Query: 253 QVFYDILEPQNHEFKQAIG 271
           +V+Y + +  + +    +G
Sbjct: 565 RVYYRLPQGYHKDLLAHVG 583


>gi|238908501 sciellin isoform 3 [Homo sapiens]
          Length = 646

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 64  SDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGI-----KLDFKSLAVVEPSMMLLE 118
           +DG +    ++   PE  ++N   + L  ++K N  +       D  +L  V+PS +   
Sbjct: 440 TDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNT 499

Query: 119 NVKRHLKRPVWINADILPGPNGNS 142
           N  ++L+  + +N+ +    NG+S
Sbjct: 500 NRDQNLENLIEVNSHVSENKNGSS 523


>gi|238908499 sciellin isoform 1 [Homo sapiens]
          Length = 688

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 64  SDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGI-----KLDFKSLAVVEPSMMLLE 118
           +DG +    ++   PE  ++N   + L  ++K N  +       D  +L  V+PS +   
Sbjct: 482 TDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNT 541

Query: 119 NVKRHLKRPVWINADILPGPNGNS 142
           N  ++L+  + +N+ +    NG+S
Sbjct: 542 NRDQNLENLIEVNSHVSENKNGSS 565


>gi|238908497 sciellin isoform 2 [Homo sapiens]
          Length = 668

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 64  SDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGI-----KLDFKSLAVVEPSMMLLE 118
           +DG +    ++   PE  ++N   + L  ++K N  +       D  +L  V+PS +   
Sbjct: 462 TDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNT 521

Query: 119 NVKRHLKRPVWINADILPGPNGNS 142
           N  ++L+  + +N+ +    NG+S
Sbjct: 522 NRDQNLENLIEVNSHVSENKNGSS 545


>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
            [Homo sapiens]
          Length = 1686

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 8/71 (11%)

Query: 182  WTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKS-----NRYSLTIWTGKNDN 236
            + +  +M Y+ N   +P    +R  L    C Q   L++K      N  SL I +G  + 
Sbjct: 1289 FVLTSDMAYVINGGEKPT---IRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPEL 1345

Query: 237  YSVEDLLYIRD 247
             S++DL Y+RD
Sbjct: 1346 TSIQDLKYVRD 1356


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 8/85 (9%)

Query: 16  LEYFLRNSQITAEDGAEITWYHAANHKAQTNEALK----STAHMIEADVLLPSDGSEHSQ 71
           L YF   S  T E+G E +W+ A  H+ Q  EA K    S    +    ++ +  S+   
Sbjct: 148 LMYF---SGATGENGIEQSWFPAVGHERQ-EEARKFDIPSMESTLNQSAMMETLYSDPHH 203

Query: 72  PIMAHPPETNSDNTLQEWLTEVMKS 96
            +  H P T++   L   L E  K+
Sbjct: 204 RVRFHNPRTSTSKELYRVLPEAKKA 228


>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
          Length = 527

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 4/47 (8%)

Query: 50  KSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKS 96
           KS  H+I A +L   + S+   P    PPE         WLTE++++
Sbjct: 274 KSIGHLIFARLLRLQESSQGEHP----PPEDEGGEPEHTWLTEMLEN 316


>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
           sapiens]
          Length = 551

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 4/47 (8%)

Query: 50  KSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKS 96
           KS  H+I A +L   + S+   P    PPE         WLTE++++
Sbjct: 284 KSIGHLIFARLLRLQESSQGEHP----PPEDEGGEPEHTWLTEMLEN 326


>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
           sapiens]
          Length = 541

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 4/47 (8%)

Query: 50  KSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKS 96
           KS  H+I A +L   + S+   P    PPE         WLTE++++
Sbjct: 274 KSIGHLIFARLLRLQESSQGEHP----PPEDEGGEPEHTWLTEMLEN 316


>gi|33188445 microfilament and actin filament cross-linker protein
           isoform a [Homo sapiens]
          Length = 5430

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 9/72 (12%)

Query: 208 VRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVE---------DLLYIRDHFDKKQVFYDI 258
           V ++ ++L+WL +K        W+  N N S +         +L   +D F   Q   ++
Sbjct: 686 VSRATAELIWLNEKEEEELAYDWSDNNSNISAKRNYFSELTMELEEKQDVFRSLQDTAEL 745

Query: 259 LEPQNHEFKQAI 270
           L  +NH  KQ +
Sbjct: 746 LSLENHPAKQTV 757


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,232,697
Number of Sequences: 37866
Number of extensions: 463116
Number of successful extensions: 1093
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1084
Number of HSP's gapped (non-prelim): 13
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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