Search of human proteins with 45243507

Search of human proteins with 45243507

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45243507 ribonuclease, RNase A family, 3 (eosinophil
cationic protein) [Homo sapiens]
         (160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45243507 ribonuclease, RNase A family, 3 (eosinophil cationic...   344   2e-95
gi|4506549 ribonuclease, RNase A family, 2 (liver, eosinophil-de...   238   2e-63
gi|5032045 ribonuclease, RNase A family, k6 [Homo sapiens]            115   1e-26
gi|153252081 ribonuclease, RNase A family, 7 [Homo sapiens]           108   2e-24
gi|21687143 ribonuclease, RNase A family, 8 [Homo sapiens]            104   4e-23
gi|38201686 pancreatic ribonuclease precursor [Homo sapiens]           69   1e-12
gi|38201684 pancreatic ribonuclease precursor [Homo sapiens]           69   1e-12
gi|4506547 pancreatic ribonuclease precursor [Homo sapiens]            69   1e-12
gi|38201682 pancreatic ribonuclease precursor [Homo sapiens]           69   1e-12
gi|4506557 ribonuclease, RNase A family, 4 precursor [Homo sapiens]    57   7e-09
gi|37577172 ribonuclease, RNase A family, 4 precursor [Homo sapi...    57   7e-09
gi|148277046 angiogenin, ribonuclease, RNase A family, 5 precurs...    37   0.006
gi|4557313 angiogenin, ribonuclease, RNase A family, 5 precursor...    37   0.006
gi|67459908 ribonuclease, RNase A family, 12 (non-active) [Homo ...    31   0.52 
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]        27   5.7  
gi|149363636 plexin B2 [Homo sapiens]                                  27   7.5  

>gi|45243507 ribonuclease, RNase A family, 3 (eosinophil cationic
           protein) [Homo sapiens]
          Length = 160

 Score =  344 bits (883), Expect = 2e-95
 Identities = 160/160 (100%), Positives = 160/160 (100%)

Query: 1   MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY 60
           MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
Sbjct: 1   MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY 60

Query: 61  RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI 120
           RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
Sbjct: 61  RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI 120

Query: 121 SNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           SNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
Sbjct: 121 SNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160


>gi|4506549 ribonuclease, RNase A family, 2 (liver,
           eosinophil-derived neurotoxin) [Homo sapiens]
          Length = 161

 Score =  238 bits (606), Expect = 2e-63
 Identities = 111/161 (68%), Positives = 126/161 (78%), Gaps = 1/161 (0%)

Query: 1   MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY 60
           MVPKLFTSQICLLLLLGL+ VEGSLH +PPQFT AQWF  QHI++   +CT AM+ INNY
Sbjct: 1   MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY 60

Query: 61  RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI 120
           + RCKNQNTFL TTFANVVNVCGN ++ CP N+T  NCH S  +VPL+HC+L  P  QNI
Sbjct: 61  QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI 120

Query: 121 SNCTYADRPGRRFYVVACDNRDP-RDSPRYPVVPVHLDTTI 160
           SNC YA  P   FY+VACDNRD  RD P+YPVVPVHLD  I
Sbjct: 121 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII 161


>gi|5032045 ribonuclease, RNase A family, k6 [Homo sapiens]
          Length = 150

 Score =  115 bits (289), Expect = 1e-26
 Identities = 66/149 (44%), Positives = 84/149 (56%), Gaps = 6/149 (4%)

Query: 12  LLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFL 71
           LLLLL L G    LHA P + T+A WF IQHI  +P +C  AM  INNY   CK+QNTFL
Sbjct: 8   LLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFL 67

Query: 72  RTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGR 131
             +F NV  VC   SI C + R  +NCH+S   V +  C L    +     C Y+     
Sbjct: 68  HDSFQNVAAVCDLLSIVCKNRR--HNCHQSSKPVNMTDCRLT---SGKYPQCRYSAAAQY 122

Query: 132 RFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           +F++VACD     D P Y +VPVHLD+ +
Sbjct: 123 KFFIVACDPPQKSDPP-YKLVPVHLDSIL 150


>gi|153252081 ribonuclease, RNase A family, 7 [Homo sapiens]
          Length = 156

 Score =  108 bits (270), Expect = 2e-24
 Identities = 59/151 (39%), Positives = 81/151 (53%), Gaps = 5/151 (3%)

Query: 10  ICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNT 69
           + LLLLLGL   E  + A+P   T +QWF IQH+  +P  C  AM+ IN +  RCK+ NT
Sbjct: 11  LLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINKHTKRCKDLNT 70

Query: 70  FLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRP 129
           FL   F++V   C    I C +     NCH+S   V L  C L    +    NC Y ++ 
Sbjct: 71  FLHEPFSSVAATCQTPKIACKNGD--KNCHQSHGAVSLTMCKLT---SGKYPNCRYKEKR 125

Query: 130 GRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
             + YVVAC     +DS ++ +VPVHLD  +
Sbjct: 126 QNKSYVVACKPPQKKDSQQFHLVPVHLDRVL 156


>gi|21687143 ribonuclease, RNase A family, 8 [Homo sapiens]
          Length = 154

 Score =  104 bits (259), Expect = 4e-23
 Identities = 59/149 (39%), Positives = 78/149 (52%), Gaps = 6/149 (4%)

Query: 12  LLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFL 71
           LLLLLGL   E  + A+P   T +QWF  QH+  +P  C  AM  IN Y  RCK+ NTFL
Sbjct: 12  LLLLLGLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINKYTERCKDLNTFL 71

Query: 72  RTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYADRPGR 131
              F++V   C   +I C    +  NCH+S   + L   +L    +    NC Y ++   
Sbjct: 72  HEPFSSVAITCQTPNIAC--KNSCKNCHQSHGPMSLTMGELT---SGKYPNCRYKEKHLN 126

Query: 132 RFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
             Y+VACD     D P YP+VPVHLD  +
Sbjct: 127 TPYIVACDPPQQGD-PGYPLVPVHLDKVV 154


>gi|38201686 pancreatic ribonuclease precursor [Homo sapiens]
          Length = 156

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 48/159 (30%), Positives = 73/159 (45%), Gaps = 18/159 (11%)

Query: 8   SQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI------SLNPPRCTIAMRAINNYR 61
           S + LLLL+ ++ V G +     + +RA+ F  QH+      S +   C   MR  N  +
Sbjct: 6   SLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQ 65

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
            RCK  NTF+     +V NVC  + + C + +   NC++S   + +  C L N       
Sbjct: 66  GRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN--GSRYP 121

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           NC Y   P  R  +VAC+          P VPVH D ++
Sbjct: 122 NCAYRTSPKERHIIVACEGS--------PYVPVHFDASV 152


>gi|38201684 pancreatic ribonuclease precursor [Homo sapiens]
          Length = 156

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 48/159 (30%), Positives = 73/159 (45%), Gaps = 18/159 (11%)

Query: 8   SQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI------SLNPPRCTIAMRAINNYR 61
           S + LLLL+ ++ V G +     + +RA+ F  QH+      S +   C   MR  N  +
Sbjct: 6   SLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQ 65

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
            RCK  NTF+     +V NVC  + + C + +   NC++S   + +  C L N       
Sbjct: 66  GRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN--GSRYP 121

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           NC Y   P  R  +VAC+          P VPVH D ++
Sbjct: 122 NCAYRTSPKERHIIVACEGS--------PYVPVHFDASV 152


>gi|4506547 pancreatic ribonuclease precursor [Homo sapiens]
          Length = 156

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 48/159 (30%), Positives = 73/159 (45%), Gaps = 18/159 (11%)

Query: 8   SQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI------SLNPPRCTIAMRAINNYR 61
           S + LLLL+ ++ V G +     + +RA+ F  QH+      S +   C   MR  N  +
Sbjct: 6   SLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQ 65

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
            RCK  NTF+     +V NVC  + + C + +   NC++S   + +  C L N       
Sbjct: 66  GRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN--GSRYP 121

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           NC Y   P  R  +VAC+          P VPVH D ++
Sbjct: 122 NCAYRTSPKERHIIVACEGS--------PYVPVHFDASV 152


>gi|38201682 pancreatic ribonuclease precursor [Homo sapiens]
          Length = 156

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 48/159 (30%), Positives = 73/159 (45%), Gaps = 18/159 (11%)

Query: 8   SQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHI------SLNPPRCTIAMRAINNYR 61
           S + LLLL+ ++ V G +     + +RA+ F  QH+      S +   C   MR  N  +
Sbjct: 6   SLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQ 65

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
            RCK  NTF+     +V NVC  + + C + +   NC++S   + +  C L N       
Sbjct: 66  GRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN--GSRYP 121

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
           NC Y   P  R  +VAC+          P VPVH D ++
Sbjct: 122 NCAYRTSPKERHIIVACEGS--------PYVPVHFDASV 152


>gi|4506557 ribonuclease, RNase A family, 4 precursor [Homo sapiens]
          Length = 147

 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 7   TSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPR-----CTIAMRAINNYR 61
           T  + LLLLL L+G+ G +     Q    Q F  QH+           C + M+      
Sbjct: 6   THSLLLLLLLTLLGL-GLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTL 64

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
           + CK  NTF+     N+ ++C   +I+C + +   NCH    +V     D  + G+    
Sbjct: 65  YHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKM--NCHEGVVKV----TDCRDTGSSRAP 118

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLD 157
           NC Y      R  V+AC+          P VPVH D
Sbjct: 119 NCRYRAIASTRRVVIACEGN--------PQVPVHFD 146


>gi|37577172 ribonuclease, RNase A family, 4 precursor [Homo
           sapiens]
          Length = 147

 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 20/156 (12%)

Query: 7   TSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPR-----CTIAMRAINNYR 61
           T  + LLLLL L+G+ G +     Q    Q F  QH+           C + M+      
Sbjct: 6   THSLLLLLLLTLLGL-GLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTL 64

Query: 62  WRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNIS 121
           + CK  NTF+     N+ ++C   +I+C + +   NCH    +V     D  + G+    
Sbjct: 65  YHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKM--NCHEGVVKV----TDCRDTGSSRAP 118

Query: 122 NCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLD 157
           NC Y      R  V+AC+          P VPVH D
Sbjct: 119 NCRYRAIASTRRVVIACEGN--------PQVPVHFD 146


>gi|148277046 angiogenin, ribonuclease, RNase A family, 5 precursor
           [Homo sapiens]
          Length = 147

 Score = 37.4 bits (85), Expect = 0.006
 Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 22/154 (14%)

Query: 12  LLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPR-----CTIAMRAINNYRWRCKN 66
           +LLL+ ++G+  +        +R   F  QH    P       C   MR        CK+
Sbjct: 7   VLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRR-RGLTSPCKD 65

Query: 67  QNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYA 126
            NTF+     ++  +C N++   PH   L    +S F+V    C L   G      C Y 
Sbjct: 66  INTFIHGNKRSIKAICENKNGN-PHRENLR-ISKSSFQVTT--CKL--HGGSPWPPCQYR 119

Query: 127 DRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
              G R  VVAC+N           +PVHLD +I
Sbjct: 120 ATAGFRNVVVACENG----------LPVHLDQSI 143


>gi|4557313 angiogenin, ribonuclease, RNase A family, 5 precursor
           [Homo sapiens]
          Length = 147

 Score = 37.4 bits (85), Expect = 0.006
 Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 22/154 (14%)

Query: 12  LLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPR-----CTIAMRAINNYRWRCKN 66
           +LLL+ ++G+  +        +R   F  QH    P       C   MR        CK+
Sbjct: 7   VLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRR-RGLTSPCKD 65

Query: 67  QNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNISNCTYA 126
            NTF+     ++  +C N++   PH   L    +S F+V    C L   G      C Y 
Sbjct: 66  INTFIHGNKRSIKAICENKNGN-PHRENLR-ISKSSFQVTT--CKL--HGGSPWPPCQYR 119

Query: 127 DRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI 160
              G R  VVAC+N           +PVHLD +I
Sbjct: 120 ATAGFRNVVVACENG----------LPVHLDQSI 143


>gi|67459908 ribonuclease, RNase A family, 12 (non-active) [Homo
           sapiens]
          Length = 147

 Score = 30.8 bits (68), Expect = 0.52
 Identities = 21/92 (22%), Positives = 33/92 (35%), Gaps = 2/92 (2%)

Query: 52  IAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCD 111
           I  R I      CK ++ F+      +  +C +       N +   C +S  +  +  C 
Sbjct: 50  IIQRVIREPDHTCKKEHVFIHERPRKINGICISPKKVACQNLSAIFCFQSETKFKMTVCQ 109

Query: 112 LINPGAQNISNCTYADRPGRRFYVVACDNRDP 143
           LI         C Y   P   F +V CD+  P
Sbjct: 110 LIE--GTRYPACRYHYSPTEGFVLVTCDDLRP 139


>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
          Length = 882

 Score = 27.3 bits (59), Expect = 5.7
 Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 2/49 (4%)

Query: 50  CTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNC 98
           C++ +  ++        Q+TF R    ++V  C    +RCP  R L  C
Sbjct: 57  CSVCLERLDTTAKVLPCQHTFCRRCLESIV--CSRHELRCPECRILVGC 103


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score = 26.9 bits (58), Expect = 7.5
 Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 9  QICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAIN 58
          Q+  L LLGL+G   SL  R   F R++   + H++++     + + A+N
Sbjct: 4  QLWALTLLGLLGAGASLRPRKLDFFRSE-KELNHLAVDEASGVVYLGAVN 52


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,050,786
Number of Sequences: 37866
Number of extensions: 298254
Number of successful extensions: 620
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 594
Number of HSP's gapped (non-prelim): 16
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.