Guide to the Human Genome
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Search of human proteins with 4507681

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507681 thyrotropin-releasing hormone receptor [Homo
sapiens]
         (398 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]      801   0.0  
gi|170932505 neuromedin U receptor 2 [Homo sapiens]                   142   4e-34
gi|4505513 opiate receptor-like 1 [Homo sapiens]                      141   1e-33
gi|33286424 opiate receptor-like 1 [Homo sapiens]                     141   1e-33
gi|222080109 orexin receptor 2 [Homo sapiens]                         135   5e-32
gi|222080095 orexin receptor 1 [Homo sapiens]                         132   5e-31
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                   126   4e-29
gi|4502455 bombesin-like receptor 3 [Homo sapiens]                    126   4e-29
gi|188497623 neuromedin U receptor 1 [Homo sapiens]                   125   5e-29
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom...   124   2e-28
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]      122   6e-28
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]       122   6e-28
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]     122   6e-28
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]     122   6e-28
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]     122   6e-28
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]     122   6e-28
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]      122   6e-28
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]     122   6e-28
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]      122   6e-28
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]      122   6e-28
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]       122   7e-28
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]      122   7e-28
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]      122   7e-28
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 122   7e-28
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  121   1e-27
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                   117   2e-26
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]          114   2e-25
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...   114   2e-25
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]                  109   5e-24
gi|119220588 melanin-concentrating hormone receptor 2 [Homo sapi...   108   1e-23

>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
          Length = 398

 Score =  801 bits (2068), Expect = 0.0
 Identities = 398/398 (100%), Positives = 398/398 (100%)

Query: 1   MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPT 60
           MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPT
Sbjct: 1   MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPT 60

Query: 61  NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT 120
           NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
Sbjct: 61  NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT 120

Query: 121 IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCG 180
           IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCG
Sbjct: 121 IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCG 180

Query: 181 YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTH 240
           YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTH
Sbjct: 181 YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTH 240

Query: 241 QNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW 300
           QNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
Sbjct: 241 QNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW 300

Query: 301 FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKES 360
           FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKES
Sbjct: 301 FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKES 360

Query: 361 DHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS 398
           DHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS
Sbjct: 361 DHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS 398


>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
          Length = 415

 Score =  142 bits (359), Expect = 4e-34
 Identities = 100/317 (31%), Positives = 164/317 (51%), Gaps = 41/317 (12%)

Query: 38  LGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSW-----V 92
           +G++GN++V LV+++ + M+TPTN YL SLAV+DL+VL+  G+P     +Y  W     +
Sbjct: 58  VGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLL-GMPL---EVYEMWRNYPFL 113

Query: 93  YGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAF 152
           +G VGC   T L      AS  SIT  ++ERY+AI HP +A+   T  RA +I+  VW F
Sbjct: 114 FGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGF 173

Query: 153 TSLYCMLWFFLLDLNISTYKDAIVI----SCGYKISRNYYSPIYLMDFGVFYVVPMILAT 208
           + L+ +    +  +    + +  ++    +C        Y+ I  +   +FY++PM + +
Sbjct: 174 SVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVIS 233

Query: 209 VLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKML 268
           VLY  +A  L                K D + +    N N    C       RK V KML
Sbjct: 234 VLYYLMALRL----------------KKDKSLEADEGNANIQRPC-------RKSVNKML 270

Query: 269 AVVVILFALLWMPYRTLVVVNSFLSSPFQE-----NWFLLFCRICIYLNSAINPVIYNLM 323
            V+V++FA+ W P+    +  SF+    +      N   +   +  YL+SA+NP+IYNL+
Sbjct: 271 FVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLL 330

Query: 324 SQKFRAAFRKLCNCKQK 340
           S++F+AAF+ + +   K
Sbjct: 331 SRRFQAAFQNVISSFHK 347


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  141 bits (355), Expect = 1e-33
 Identities = 87/323 (26%), Positives = 162/323 (50%), Gaps = 37/323 (11%)

Query: 18  AVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVA 77
           A + L  +V  + L L +C  G++GN +V+ V++R   M+T TN Y+ +LA+AD +VL+ 
Sbjct: 44  AFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT 103

Query: 78  AGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLC 137
                 TD + G W +G   C  +  + Y  +  S+ ++TA +++RY+AICHPI+A  + 
Sbjct: 104 LPFQG-TDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR 162

Query: 138 TFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKI--SRNYYSPIYLMD 195
           T S+A+ + + +WA  S+  +    +    +   +    I C  +I   ++Y+ P++ + 
Sbjct: 163 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEE----IECLVEIPTPQDYWGPVFAIC 218

Query: 196 FGVF-YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCF 254
             +F ++VP+++ +V Y  + R L    + S  +E  +                      
Sbjct: 219 IFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDR---------------------- 256

Query: 255 NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQEN--WFLLFCRICIYLN 312
                + +++T+++ VVV +F   W P +  V+       P  E     L FC    Y+N
Sbjct: 257 -----NLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVN 311

Query: 313 SAINPVIYNLMSQKFRAAFRKLC 335
           S +NP++Y  + + F+A FRK C
Sbjct: 312 SCLNPILYAFLDENFKACFRKFC 334


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  141 bits (355), Expect = 1e-33
 Identities = 87/323 (26%), Positives = 162/323 (50%), Gaps = 37/323 (11%)

Query: 18  AVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVA 77
           A + L  +V  + L L +C  G++GN +V+ V++R   M+T TN Y+ +LA+AD +VL+ 
Sbjct: 44  AFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT 103

Query: 78  AGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLC 137
                 TD + G W +G   C  +  + Y  +  S+ ++TA +++RY+AICHPI+A  + 
Sbjct: 104 LPFQG-TDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVR 162

Query: 138 TFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKI--SRNYYSPIYLMD 195
           T S+A+ + + +WA  S+  +    +    +   +    I C  +I   ++Y+ P++ + 
Sbjct: 163 TSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEE----IECLVEIPTPQDYWGPVFAIC 218

Query: 196 FGVF-YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCF 254
             +F ++VP+++ +V Y  + R L    + S  +E  +                      
Sbjct: 219 IFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDR---------------------- 256

Query: 255 NSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQEN--WFLLFCRICIYLN 312
                + +++T+++ VVV +F   W P +  V+       P  E     L FC    Y+N
Sbjct: 257 -----NLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVN 311

Query: 313 SAINPVIYNLMSQKFRAAFRKLC 335
           S +NP++Y  + + F+A FRK C
Sbjct: 312 SCLNPILYAFLDENFKACFRKFC 334


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  135 bits (341), Expect = 5e-32
 Identities = 90/333 (27%), Positives = 161/333 (48%), Gaps = 21/333 (6%)

Query: 23  EYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPN 82
           EY+ V I   +I+  + ++GN++V + V +  HMRT TN ++V+L++AD++V +      
Sbjct: 52  EYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPAT 111

Query: 83  ITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142
           +   I  +W +G   C  I YLQ + ++ S  +++   ++R+ AICHP+   F  T  RA
Sbjct: 112 LVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL--MFKSTAKRA 169

Query: 143 KKIIIFVWAFTSLYCMLWFFLLDLNI----STYKDAIVISCGYKISRNYYSPIY-LMDFG 197
           +  I+ +W  + +  +    +++ +        K  +   C  +     Y  +Y +  F 
Sbjct: 170 RNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFL 229

Query: 198 VFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKN-DSTHQNTNLNVNTSNRCFN- 255
           V Y+ P+ L  + Y  I R L+   IP       + WK      Q       T +R    
Sbjct: 230 VTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAV 289

Query: 256 ----STVSSRKQVTKMLAVVVILFALLWMPYRTLVVV----NSFLSSPFQEN---WFLLF 304
                 + +R++  +ML +V+++FA+ ++P   L V+      F  +  +E    WF  F
Sbjct: 290 AAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWF-TF 348

Query: 305 CRICIYLNSAINPVIYNLMSQKFRAAFRKLCNC 337
               +Y NSA NP+IYN +S KFR  F+   +C
Sbjct: 349 SHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  132 bits (332), Expect = 5e-31
 Identities = 101/355 (28%), Positives = 172/355 (48%), Gaps = 26/355 (7%)

Query: 2   ENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTN 61
           E+E +  L +  L P+     +Y+ V I   + +  + +VGN +V L V R  HMRT TN
Sbjct: 28  EDEFLRYLWRDYLYPK-----QYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTN 82

Query: 62  CYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTI 121
            ++V+L++AD++V       ++   I  SW++G+  C  I YLQ + ++ +  +++   +
Sbjct: 83  YFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIAL 142

Query: 122 ERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLD----LNISTYKDAIVI 177
           +R+ AICHP+   F  T  RA+  I+ +WA +    +    +++    L     +  +  
Sbjct: 143 DRWYAICHPL--LFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFS 200

Query: 178 SCGYKISRNYYSPIY-LMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKN 236
            C  + + + Y  IY    F V Y+ P+ L  + Y  I R L+   IP       + WK 
Sbjct: 201 VCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKR 260

Query: 237 DS-----THQNTNLNVNTSNRCFNSTVS---SRKQVTKMLAVVVILFALLWMPYRTLVVV 288
            S       Q  +       R F + V    +R++  KML VV+++FAL ++P   L V+
Sbjct: 261 PSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVL 320

Query: 289 ----NSFLSSPFQENWF--LLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNC 337
                 F  +  +E  +    F    +Y NSA NP+IYN +S KFR  F+   +C
Sbjct: 321 KRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score =  126 bits (316), Expect = 4e-29
 Identities = 87/335 (25%), Positives = 162/335 (48%), Gaps = 41/335 (12%)

Query: 17  RAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLV 76
           R+  +L   +    L   +C +G++GN++V+  ++R   M+T TN Y+ +LA+AD   L 
Sbjct: 41  RSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALAD--ALA 98

Query: 77  AAGLP-NITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQF 135
            + LP      +  +W +G + C  +  + Y  +  S  ++T  +++RYIA+CHP+KA  
Sbjct: 99  TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD 158

Query: 136 LCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYY--SPIYL 193
             T ++AK I I +W   S    +   ++ + ++  +D  V+      S ++Y  +   +
Sbjct: 159 FRTPAKAKLINICIWVLAS---GVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKI 215

Query: 194 MDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRC 253
             F   +VVP+++ TV YG +   L    + S  KE  +                     
Sbjct: 216 CVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDR--------------------- 254

Query: 254 FNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICI---Y 310
                 S +++T+M+ VVV  F + W P    V+V + +    ++   +    +CI   Y
Sbjct: 255 ------SLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGY 308

Query: 311 LNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKP 345
            NS++NPV+Y  + + F+  FR+LC   +KP  +P
Sbjct: 309 ANSSLNPVLYAFLDENFKRCFRQLC---RKPCGRP 340


>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
          Length = 399

 Score =  126 bits (316), Expect = 4e-29
 Identities = 84/324 (25%), Positives = 158/324 (48%), Gaps = 35/324 (10%)

Query: 34  IICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVY 93
           +I  +GI+GN +++ V  +TK M+T  N ++ SLA  DL++L+     + T  +   W++
Sbjct: 56  VIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLF 115

Query: 94  GYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFT 153
           G +GC  +++++   +  S  ++T  + +RY A+  P++ Q      +       VW  +
Sbjct: 116 GRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVS 175

Query: 154 SLYCMLWFFLLDLNISTYKD----AIVISC-GYKISRNYYSPIY-LMDFGVFYVVPMILA 207
            ++ +     +  N+ T++D        SC  Y +S+     I+ L+ F VFY++P+ + 
Sbjct: 176 MIFALP--EAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSII 233

Query: 208 TVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKM 267
           +V Y  IAR L+ + +    +E S   K                      + SRK++ + 
Sbjct: 234 SVYYSLIARTLYKSTLNIPTEEQSHARKQ---------------------IESRKRIART 272

Query: 268 LAVVVILFALLWMPYRTLVVVNSFLSSPFQEN-----WFLLFCRICIYLNSAINPVIYNL 322
           + V+V LFAL W+P   L + +SF S  + +       F +F R+  + NS +NP     
Sbjct: 273 VLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYW 332

Query: 323 MSQKFRAAFR-KLCNCKQKPTEKP 345
           +S+ F+  F+ +L  CK +  E P
Sbjct: 333 LSKSFQKHFKAQLFCCKAERPEPP 356


>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
          Length = 426

 Score =  125 bits (315), Expect = 5e-29
 Identities = 109/358 (30%), Positives = 173/358 (48%), Gaps = 51/358 (14%)

Query: 3   NETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC 62
           N T   L    L P+          T LL+ ++   G VGN +  LV++R K MRTPTN 
Sbjct: 41  NLTDEALRLKYLGPQQTELFMPICATYLLIFVV---GAVGNGLTCLVILRHKAMRTPTNY 97

Query: 63  YLVSLAVADLMVLVAAGLPNITDSIYGSW-----VYGYVGCLCITYLQYLGINASSCSIT 117
           YL SLAV+DL+VL+  GLP     +Y  W     + G  GC   T L  +   AS  ++T
Sbjct: 98  YLFSLAVSDLLVLL-VGLPL---ELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVT 153

Query: 118 AFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCML----WFFLLDLNI---ST 170
           A ++ERY+A+ HP++A+ + T +  ++++  VW    L C L       +  L++     
Sbjct: 154 ALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAML-CSLPNTSLHGIRQLHVPCRGP 212

Query: 171 YKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIA------RILFLNPIP 224
             D+ V  C     R  Y+ +      +F+ +PM + +VLY  I       R+L +    
Sbjct: 213 VPDSAV--CMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLM---- 266

Query: 225 SDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRT 284
               + +K   + +        +   +R        R+QVTKML V+V++F + W P+  
Sbjct: 267 ----QEAKGRGSAAARSRYTCRLQQHDR-------GRRQVTKMLFVLVVVFGICWAPFHA 315

Query: 285 LVVVNSFLSSPFQENWFLLFCRICI------YLNSAINPVIYNLMSQKFRAAFRK-LC 335
             V+ S +S  + +   L F  + +      YL SA NPV+Y+LMS +FR  F++ LC
Sbjct: 316 DRVMWSVVSQ-WTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALC 372


>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
           sapiens]
          Length = 366

 Score =  124 bits (310), Expect = 2e-28
 Identities = 87/306 (28%), Positives = 140/306 (45%), Gaps = 33/306 (10%)

Query: 38  LGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVG 97
           +GI GN++ +LVV R + +RT TN YL S+A +DL++ +   L  +    Y  W +G + 
Sbjct: 56  VGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLL 115

Query: 98  CLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYC 157
           C    ++      A+  +ITA ++ERY AIC P++A+ + T  R K +I  +WA      
Sbjct: 116 CKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSA 175

Query: 158 MLWFFLLDL---NISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFI 214
              F L+ +   N +   D           R+    + +    +F+ +P+   TVLY  I
Sbjct: 176 GPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLI 235

Query: 215 ARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVIL 274
            R               K W+          ++   N          KQ  KMLAVVV  
Sbjct: 236 GR---------------KLWRRRRGDAVVGASLRDQN---------HKQTVKMLAVVVFA 271

Query: 275 FALLWMPYRT--LVVVNSFLSSPFQENWFLLFCR----ICIYLNSAINPVIYNLMSQKFR 328
           F L W+P+     +   SF     +      +C     +  YL++AINP++YN+MS+K+R
Sbjct: 272 FILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331

Query: 329 AAFRKL 334
            A  +L
Sbjct: 332 VAVFRL 337


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 164 ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 221

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 222 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 281

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 282 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 337

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 338 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 370

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 371 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 428

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 429 VLYAFLDENFKRCFREFC 446


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
          Length = 389

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
          Length = 418

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score =  122 bits (306), Expect = 6e-28
 Identities = 87/318 (27%), Positives = 153/318 (48%), Gaps = 44/318 (13%)

Query: 27  VTIL-LVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLP-NIT 84
           +TI+ L  I+C +G+ GN +V+ V++R   M+T TN Y+ +LA+AD   L  + LP    
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD--ALATSTLPFQSV 128

Query: 85  DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKK 144
           + + G+W +G + C  +  + Y  +  S  ++   +++RYIA+CHP+KA    T   AK 
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKI 188

Query: 145 IIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVF---YV 201
           I +  W  +S   +   F+     + Y+    I C    S   +    L+   VF   ++
Sbjct: 189 INVCNWILSSAIGLPVMFMA---TTKYRQG-SIDCTLTFSHPTWYWENLLKICVFIFAFI 244

Query: 202 VPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSR 261
           +P+++ TV YG +   L    + S  KE  +                           + 
Sbjct: 245 MPVLIITVCYGLMILRLKSVRMLSGSKEKDR---------------------------NL 277

Query: 262 KQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSP---FQE-NWFLLFCRICIYLNSAINP 317
           +++T+M+ VVV +F + W P    V++ + ++ P   FQ  +W   FC    Y NS +NP
Sbjct: 278 RRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWH--FCIALGYTNSCLNP 335

Query: 318 VIYNLMSQKFRAAFRKLC 335
           V+Y  + + F+  FR+ C
Sbjct: 336 VLYAFLDENFKRCFREFC 353


>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
          Length = 420

 Score =  122 bits (305), Expect = 7e-28
 Identities = 88/348 (25%), Positives = 157/348 (45%), Gaps = 65/348 (18%)

Query: 26  VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD 85
           +++  L+  +C   ++GN +V  +VMR KHM T TN ++++LA++DL+V +      + D
Sbjct: 49  IISYFLIFFLC---MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 105

Query: 86  SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKI 145
           +I   W +G   C     +Q + + AS  ++ A  ++R+  + +P K +   T   A  I
Sbjct: 106 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL--TIKTAFVI 163

Query: 146 IIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKI---SRNYYSPIY---------- 192
           I+ +W            +L +    Y         Y++   S+N  SP+Y          
Sbjct: 164 IMIIWVLAITIMSPSAVMLHVQEEKY---------YRVRLNSQNKTSPVYWCREDWPNQE 214

Query: 193 ------LMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLN 246
                  + F   Y+ P+ L  ++YG I   LF   +P   ++N + W            
Sbjct: 215 MRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW------------ 262

Query: 247 VNTSNRCFNSTVSSRKQ-VTKMLAVVVILFALLWMPYRTLVVVNSFLS-SPFQ----ENW 300
                      VS +KQ + KML +V +LF L W+P  TL++++ +   SP +      +
Sbjct: 263 ---------HVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIY 313

Query: 301 FLLFCRICIYLNSAINPVIYNLMSQKFRAAFR-----KLCNCKQKPTE 343
              F     + NS++NP+IY   ++ FR  F+     +LC  + KP E
Sbjct: 314 IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPME 361


>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
          Length = 522

 Score =  122 bits (305), Expect = 7e-28
 Identities = 88/348 (25%), Positives = 157/348 (45%), Gaps = 65/348 (18%)

Query: 26  VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD 85
           +++  L+  +C   ++GN +V  +VMR KHM T TN ++++LA++DL+V +      + D
Sbjct: 151 IISYFLIFFLC---MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 207

Query: 86  SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKI 145
           +I   W +G   C     +Q + + AS  ++ A  ++R+  + +P K +   T   A  I
Sbjct: 208 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL--TIKTAFVI 265

Query: 146 IIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKI---SRNYYSPIY---------- 192
           I+ +W            +L +    Y         Y++   S+N  SP+Y          
Sbjct: 266 IMIIWVLAITIMSPSAVMLHVQEEKY---------YRVRLNSQNKTSPVYWCREDWPNQE 316

Query: 193 ------LMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLN 246
                  + F   Y+ P+ L  ++YG I   LF   +P   ++N + W            
Sbjct: 317 MRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW------------ 364

Query: 247 VNTSNRCFNSTVSSRKQ-VTKMLAVVVILFALLWMPYRTLVVVNSFLS-SPFQ----ENW 300
                      VS +KQ + KML +V +LF L W+P  TL++++ +   SP +      +
Sbjct: 365 ---------HVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIY 415

Query: 301 FLLFCRICIYLNSAINPVIYNLMSQKFRAAFR-----KLCNCKQKPTE 343
              F     + NS++NP+IY   ++ FR  F+     +LC  + KP E
Sbjct: 416 IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPME 463


>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
          Length = 423

 Score =  122 bits (305), Expect = 7e-28
 Identities = 88/348 (25%), Positives = 157/348 (45%), Gaps = 65/348 (18%)

Query: 26  VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD 85
           +++  L+  +C   ++GN +V  +VMR KHM T TN ++++LA++DL+V +      + D
Sbjct: 52  IISYFLIFFLC---MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 108

Query: 86  SIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKI 145
           +I   W +G   C     +Q + + AS  ++ A  ++R+  + +P K +   T   A  I
Sbjct: 109 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL--TIKTAFVI 166

Query: 146 IIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKI---SRNYYSPIY---------- 192
           I+ +W            +L +    Y         Y++   S+N  SP+Y          
Sbjct: 167 IMIIWVLAITIMSPSAVMLHVQEEKY---------YRVRLNSQNKTSPVYWCREDWPNQE 217

Query: 193 ------LMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLN 246
                  + F   Y+ P+ L  ++YG I   LF   +P   ++N + W            
Sbjct: 218 MRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW------------ 265

Query: 247 VNTSNRCFNSTVSSRKQ-VTKMLAVVVILFALLWMPYRTLVVVNSFLS-SPFQ----ENW 300
                      VS +KQ + KML +V +LF L W+P  TL++++ +   SP +      +
Sbjct: 266 ---------HVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIY 316

Query: 301 FLLFCRICIYLNSAINPVIYNLMSQKFRAAFR-----KLCNCKQKPTE 343
              F     + NS++NP+IY   ++ FR  F+     +LC  + KP E
Sbjct: 317 IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPME 364


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  122 bits (305), Expect = 7e-28
 Identities = 89/372 (23%), Positives = 176/372 (47%), Gaps = 63/372 (16%)

Query: 27  VTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDS 86
           + I L  +I  + + GN+++++V+  ++ +RT TN +L+SLAV+DL++ VA     +  +
Sbjct: 56  IRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPN 115

Query: 87  IYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKII 146
           + G++++G V C  ++YL  + ++ S+ S+ A  +ERY AIC P++A+   T S A ++I
Sbjct: 116 LMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVI 175

Query: 147 IFVWAFTSLYCMLWFFLLDLNISTYKDAI---VISCGYKIS----RNYYSPIYLMDFGVF 199
           +  W  + L       ++   + T    +   V+ C ++      R  +S + L+   + 
Sbjct: 176 VATWLLSGL------LMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLL---LL 226

Query: 200 YVVPMILATVLYGFIARILFL-------NPIPSDPKENSKTWKNDSTHQNTNLNVNT--- 249
           + +P ++  V YG I+R L+L       +   S  +  ++     + HQN      T   
Sbjct: 227 FFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAV 286

Query: 250 ---SNRCF---------------------------NSTVSSRKQVTKMLAVVVILFALLW 279
              S+ C+                            + + ++K+V +ML V+V+LF L W
Sbjct: 287 GEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCW 346

Query: 280 MPYRTLVVVNSFLSSPFQENWF----LLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLC 335
           +P  +     +F   P          + F  +  Y ++ +NP++Y  M ++FR A  + C
Sbjct: 347 LPVYSANTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETC 405

Query: 336 N--CKQKPTEKP 345
              C + P  +P
Sbjct: 406 ARCCPRPPRARP 417


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  121 bits (304), Expect = 1e-27
 Identities = 105/387 (27%), Positives = 183/387 (47%), Gaps = 63/387 (16%)

Query: 1   MENETVSELNQTQLQPRAVVALEYQ-VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTP 59
           +ENET+  L+Q    PR   + E+Q  V ILL  +I  L ++GN +V+ V++R K MRT 
Sbjct: 22  LENETLFCLDQ----PRP--SKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTV 75

Query: 60  TNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAF 119
           TN +L+SLAV+DLM+ +     N+  ++   +++G   C   TY     ++ S+ ++ A 
Sbjct: 76  TNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAI 135

Query: 120 TIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFT-------SLYCMLWFFLLDLNISTYK 172
           ++ERY AIC P++++   T S A K+I   W  +        +Y  L  F  + N  T  
Sbjct: 136 SLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKN-NNQTAN 194

Query: 173 DAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLN-PIPSDPKENS 231
               +     + +++++ + L    + +++P I+  V YG I+  L+      +  K+++
Sbjct: 195 MCRFLLPNDVMQQSWHTFLLL----ILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSA 250

Query: 232 KTWKNDSTHQN---------------------TNLNVNTSNRC----FNSTVS---SRKQ 263
           K  K  +T                          L+  +S+R      NS+ +   ++K+
Sbjct: 251 KERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKR 310

Query: 264 VTKMLAVVVILFALLWMP---------YRTLVVVNSFLSSPFQENWFLLFCRICIYLNSA 314
           V +ML V+V+LF L WMP         Y T         +P      + F  +  Y +S 
Sbjct: 311 VIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTP------ISFILLLSYTSSC 364

Query: 315 INPVIYNLMSQKFRAAFRKLCNCKQKP 341
           +NP+IY  M+++FR  F     C   P
Sbjct: 365 VNPIIYCFMNKRFRLGFMATFPCCPNP 391


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score =  117 bits (293), Expect = 2e-26
 Identities = 88/329 (26%), Positives = 155/329 (47%), Gaps = 37/329 (11%)

Query: 13  QLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADL 72
           QL+P A ++    V+   +  ++  +G+VGN +V+ V++R   M+T TN Y+ +LA+AD 
Sbjct: 48  QLEP-AHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADA 106

Query: 73  MVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIK 132
           +V       + T  +  SW +G V C  +  + Y  +  S  ++T  +++RYIA+CHP+K
Sbjct: 107 LVTTTMPFQS-TVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVK 165

Query: 133 AQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIY 192
           A    T  +AK I I +W  +S   +    L    +   +D  VI C  +   + YS   
Sbjct: 166 ALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR--EDVDVIECSLQFPDDDYSWWD 223

Query: 193 L-MDFGVF---YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVN 248
           L M   VF   +V+P+++  V Y  +   L            S    + S  ++ NL   
Sbjct: 224 LFMKICVFIFAFVIPVLIIIVCYTLMILRL-----------KSVRLLSGSREKDRNL--- 269

Query: 249 TSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWF--LLFCR 306
                        +++T+++ VVV +F + W P    ++V +  S+           FC 
Sbjct: 270 -------------RRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCI 316

Query: 307 ICIYLNSAINPVIYNLMSQKFRAAFRKLC 335
              Y NS++NP++Y  + + F+  FR  C
Sbjct: 317 ALGYTNSSLNPILYAFLDENFKRCFRDFC 345


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score =  114 bits (284), Expect = 2e-25
 Identities = 86/324 (26%), Positives = 143/324 (44%), Gaps = 31/324 (9%)

Query: 24  YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNI 83
           Y +  +  V+I+  +G++GNI ++ +    K MR   N ++ SLA+ DL++L+     + 
Sbjct: 41  YVIPAVYGVIIL--IGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDA 98

Query: 84  TDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAK 143
           +  +   W++G +GC  I ++Q   +  S  ++TA + +RY AI  P+  Q      +  
Sbjct: 99  SRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKIC 158

Query: 144 KIIIFVWAFTSLYCMLWFFLLDLN--ISTYKDAIVISCG-YKISRNYYSPIYLM-DFGVF 199
               F+W  + L  +      DL+       +   ISC  Y  S   +  I+ M  F VF
Sbjct: 159 LKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVF 218

Query: 200 YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVS 259
           YV+P+ + +V Y FIA+ L  +                      NL V   N      + 
Sbjct: 219 YVIPLSIISVYYYFIAKNLIQSAY--------------------NLPVE-GNIHVKKQIE 257

Query: 260 SRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRIC----IYLNSAI 315
           SRK++ K + V V LFA  W+P   + +  S+  S    +       IC     + NS +
Sbjct: 258 SRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCV 317

Query: 316 NPVIYNLMSQKFRAAFRKLCNCKQ 339
           NP    L+S+ FR  F     C Q
Sbjct: 318 NPFALYLLSKSFRKQFNTQLLCCQ 341


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score =  114 bits (284), Expect = 2e-25
 Identities = 86/324 (26%), Positives = 143/324 (44%), Gaps = 31/324 (9%)

Query: 24  YQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNI 83
           Y +  +  V+I+  +G++GNI ++ +    K MR   N ++ SLA+ DL++L+     + 
Sbjct: 25  YVIPAVYGVIIL--IGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDA 82

Query: 84  TDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAK 143
           +  +   W++G +GC  I ++Q   +  S  ++TA + +RY AI  P+  Q      +  
Sbjct: 83  SRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKIC 142

Query: 144 KIIIFVWAFTSLYCMLWFFLLDLN--ISTYKDAIVISCG-YKISRNYYSPIYLM-DFGVF 199
               F+W  + L  +      DL+       +   ISC  Y  S   +  I+ M  F VF
Sbjct: 143 LKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVF 202

Query: 200 YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVS 259
           YV+P+ + +V Y FIA+ L  +                      NL V   N      + 
Sbjct: 203 YVIPLSIISVYYYFIAKNLIQSAY--------------------NLPVE-GNIHVKKQIE 241

Query: 260 SRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRIC----IYLNSAI 315
           SRK++ K + V V LFA  W+P   + +  S+  S    +       IC     + NS +
Sbjct: 242 SRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCV 301

Query: 316 NPVIYNLMSQKFRAAFRKLCNCKQ 339
           NP    L+S+ FR  F     C Q
Sbjct: 302 NPFALYLLSKSFRKQFNTQLLCCQ 325


>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
          Length = 381

 Score =  109 bits (272), Expect = 5e-24
 Identities = 100/388 (25%), Positives = 167/388 (43%), Gaps = 57/388 (14%)

Query: 2   ENETVSELNQTQLQPR-----------------AVVALEYQVVTILLVLIICGLGIVGNI 44
           EN+TV E+   Q  P+                 +   +E QVV IL    I  LG++GN 
Sbjct: 10  ENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNS 69

Query: 45  MVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYL 104
           +V+ VV++ K MRT TN ++ +LAVADL+V        +T ++ G W  G V C  + Y 
Sbjct: 70  LVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYA 129

Query: 105 QYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCM-LWFFL 163
           Q L +  S+ ++T   ++R+  I + ++++     S    II   W  ++L    L  F 
Sbjct: 130 QGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFL--IIGLAWGISALLASPLAIFR 187

Query: 164 LDLNISTYKDAIVISCGYK---ISRNYYSPIY-LMDFGVFYVVPMILATVLYGFIARILF 219
               I    D  +++C  K     ++ Y  +Y L    + YV+P+ + +  Y  I   L 
Sbjct: 188 EYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK 247

Query: 220 LNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLW 279
            +  P           ND  HQ                   R++ TKML  VV++FA+ W
Sbjct: 248 NHVSPGA--------ANDHYHQR------------------RQKTTKMLVCVVVVFAVSW 281

Query: 280 MP---YRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCN 336
           +P   ++  V ++S +    +         I    ++  NP++Y  M+  +R AF     
Sbjct: 282 LPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFR 341

Query: 337 CKQK----PTEKPANYSVALNYSVIKES 360
           C+Q+     +E    +    N  V K S
Sbjct: 342 CEQRLDAIHSEVSVTFKAKKNLEVRKNS 369


>gi|119220588 melanin-concentrating hormone receptor 2 [Homo
           sapiens]
          Length = 340

 Score =  108 bits (269), Expect = 1e-23
 Identities = 91/331 (27%), Positives = 161/331 (48%), Gaps = 44/331 (13%)

Query: 26  VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITD 85
           V+   ++ IIC  G+VGNI++V  ++R++    P + Y+ +LAVADL+ +V  G+P +  
Sbjct: 35  VILPSMIGIICSTGLVGNILIVFTIIRSRKKTVP-DIYICNLAVADLVHIV--GMPFLIH 91

Query: 86  SIY--GSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAK 143
                G WV+G   C  IT L      A S  +T  +++RY A+  P +     T  +  
Sbjct: 92  QWARGGEWVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFRLTRWRTRYKTI 151

Query: 144 KIIIFVWAFTSLYCM-LWFFLLDLNISTYKDAIVISCGYKISRN---YYSPIYLMDFGVF 199
           +I + +WA + +  + +W +     +  +KD  V SC + ++      +  +YL     F
Sbjct: 152 RINLGLWAASFILALPVWVY---SKVIKFKDG-VESCAFDLTSPDDVLWYTLYLTITTFF 207

Query: 200 YVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVS 259
           + +P+IL       +  IL L            TW+            N   RC N +V 
Sbjct: 208 FPLPLIL-------VCYILIL----------CYTWE--------MYQQNKDARCCNPSVP 242

Query: 260 SRK--QVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICI-YLNSAIN 316
            ++  ++TKM+ V+V++F L   PY  + +VN  +  P    +   +  IC+ Y +S+IN
Sbjct: 243 KQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSSIN 302

Query: 317 PVIYNLMSQKFRAAFRKLCNCKQKPTEKPAN 347
           P +Y L+S  F+   ++L   +++ TEK  N
Sbjct: 303 PFLYILLSGNFQ---KRLPQIQRRATEKEIN 330


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,272,173
Number of Sequences: 37866
Number of extensions: 526123
Number of successful extensions: 3649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 533
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 1793
Number of HSP's gapped (non-prelim): 1367
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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