Search of human proteins with 4507013

Search of human proteins with 4507013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507013 solute carrier family 2 (facilitated
glucose/fructose transporter), member 5 isoform 1 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   979   0.0  
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   598   e-171
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   439   e-123
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...   435   e-122
gi|166795299 solute carrier family 2 (facilitated glucose transp...   393   e-109
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   389   e-108
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   389   e-108
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   389   e-108
gi|4507011 glucose transporter 4 [Homo sapiens]                       387   e-107
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   373   e-103
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   363   e-100
gi|23592238 glucose transporter 14 [Homo sapiens]                     350   1e-96
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   341   1e-93
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   153   4e-37
gi|203098995 solute carrier family 2 (facilitated glucose transp...   145   1e-34
gi|223029432 solute carrier family 2 (facilitated glucose transp...   134   1e-31
gi|223029430 solute carrier family 2 (facilitated glucose transp...   124   2e-28
gi|21553331 solute carrier family 2 (facilitated glucose transpo...   114   2e-25
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           98   2e-20
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            70   3e-12
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    68   2e-11
gi|11415038 solute carrier family 22 member 3 [Homo sapiens]           67   5e-11
gi|166197673 solute carrier family 22, member 15 [Homo sapiens]        65   2e-10
gi|170650643 solute carrier family 22, member 23 isoform a [Homo...    65   2e-10
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6...    62   2e-09
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1...    62   2e-09
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    62   2e-09
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    62   2e-09
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        61   2e-09
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    59   1e-08

>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  979 bits (2530), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE 60
           MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE
Sbjct: 1   MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE 60

Query: 61  FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR 120
           FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR
Sbjct: 61  FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR 120

Query: 121 VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF 180
           VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF
Sbjct: 121 VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF 180

Query: 181 GLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGW 240
           GLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGW
Sbjct: 181 GLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGW 240

Query: 241 DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA 300
           DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA
Sbjct: 241 DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA 300

Query: 301 DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT 360
           DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT
Sbjct: 301 DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT 360

Query: 361 AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW 420
           AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW
Sbjct: 361 AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW 420

Query: 421 LSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNK 480
           LSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNK
Sbjct: 421 LSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNK 480

Query: 481 VSEVYPEKEELKELPPVTSEQ 501
           VSEVYPEKEELKELPPVTSEQ
Sbjct: 481 VSEVYPEKEELKELPPVTSEQ 501


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  598 bits (1542), Expect = e-171
 Identities = 296/491 (60%), Positives = 377/491 (76%), Gaps = 1/491 (0%)

Query: 9   KEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLT 68
           +EGRL   L LATL AAFGS+FQYGYN++ VN+P  + + FYNETY+ R   FM+   + 
Sbjct: 15  REGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLML 74

Query: 69  LLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELI 128
           LLWS TVSMFP GG +GSLLVG LV+  GRKG LL NNIF+I+PAILMG S+VA +FELI
Sbjct: 75  LLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELI 134

Query: 129 IISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188
           + SR+++G+CAG+S + +PMYLGELAPKNLRG +G + ++F+ VG+ +AQIF L+ +L N
Sbjct: 135 VFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGN 194

Query: 189 VDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVA 248
             GWP+LL LTGVPA LQLL LPFFPESPRY LIQK DEA A++AL+ LRG   ++ E+ 
Sbjct: 195 PAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELE 254

Query: 249 EIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAG 308
           ++R E  AE+A G +SVL L  +RSLRWQLLSIIVLM GQQLSG+NAI YYAD IY SAG
Sbjct: 255 DMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAG 314

Query: 309 VPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDT 368
           V   H QYVT G+G VN+VMT  +  +VE LGRR LLL G+ IC  AC VLT  L  Q+ 
Sbjct: 315 VEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNR 374

Query: 369 VSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGL 428
           V  + Y+ I+CV +Y+ GH++GPSP+P+++ TEIFLQSSR +AFMV G+VHWL+NF +G 
Sbjct: 375 VPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGF 434

Query: 429 IFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEK 488
           +FP IQE +G YSFI+FA ICLLT IYI++++PETK KTF+EIN+IF K N+V ++  EK
Sbjct: 435 LFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRV-KLPEEK 493

Query: 489 EELKELPPVTS 499
           EE  +  P T+
Sbjct: 494 EETIDAGPPTA 504


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  439 bits (1128), Expect = e-123
 Identities = 221/490 (45%), Positives = 319/490 (65%), Gaps = 3/490 (0%)

Query: 2   EQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEF 61
           E+ D + K+   +  L +A+L  AFGSSF YGYN++ VN+P   ++ FYNE++  R G  
Sbjct: 12  EESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRP 71

Query: 62  MEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRV 121
           ++   LTLLWSVTVS+F  GG +G+L+V  +    GRK  LL NN F+I  A+LM CS  
Sbjct: 72  IDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQ 131

Query: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181
           A +FE++I+ R ++GI  GV+ +V+PMYL E++PK +RG+LG V  +FI +G+   Q+ G
Sbjct: 132 AGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLG 191

Query: 182 LRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD 241
           L  LL     WP L G+  VPA +QLL LPF P+SPRYLL++K +EA A KA QT  G  
Sbjct: 192 LPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKA 251

Query: 242 SVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYAD 301
            V +EV E+  E   +++   +SVL+L R   +RWQ++++IV M   QL G+NAI++Y +
Sbjct: 252 DVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTN 311

Query: 302 QIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTA 361
            I+  AG+P   + YVT  TG +  +    +  V+E LGRR LL+ GF +  +    LT 
Sbjct: 312 SIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 371

Query: 362 ALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWL 421
            L LQD   W+PY+SIV +++ +     GP  IP +L  E F QS RP+AF++ G+V+WL
Sbjct: 372 TLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWL 431

Query: 422 SNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKV 481
           SNF VGL+FPFIQ+ L  Y F+VFA IC+   IY++ ++PETK +T+ EI+Q F+K NK 
Sbjct: 432 SNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNK- 490

Query: 482 SEVYPEKEEL 491
              YP +E++
Sbjct: 491 --AYPPEEKI 498


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score =  435 bits (1119), Expect = e-122
 Identities = 218/475 (45%), Positives = 312/475 (65%), Gaps = 3/475 (0%)

Query: 17  LALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVS 76
           L +A+L  AFGSSF YGYN++ VN+P   ++ FYNE++  R G  ++   LTLLWSVTVS
Sbjct: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115

Query: 77  MFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVG 136
           +F  GG +G+L+V  +    GRK  LL NN F+I  A+LM CS  A +FE++I+ R ++G
Sbjct: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175

Query: 137 ICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILL 196
           I  GV+ +V+PMYL E++PK +RG+LG V  +FI +G+   Q+ GL  LL     WP L 
Sbjct: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235

Query: 197 GLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEA 256
           G+  VPA +QLL LPF P+SPRYLL++K +EA A KA QT  G   V +EV E+  E   
Sbjct: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295

Query: 257 EKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQY 316
           +++   +SVL+L R   +RWQ++++IV M   QL G+NAI++Y + I+  AG+P   + Y
Sbjct: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355

Query: 317 VTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYIS 376
           VT  TG +  +    +  V+E LGRR LL+ GF +  +    LT  L LQD   W+PY+S
Sbjct: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415

Query: 377 IVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEG 436
           IV +++ +     GP  IP +L  E F QS RP+AF++ G+V+WLSNF VGL+FPFIQ+ 
Sbjct: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475

Query: 437 LGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEKEEL 491
           L  Y F+VFA IC+   IY++ ++PETK +T+ EI+Q F+K NK    YP +E++
Sbjct: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNK---AYPPEEKI 527


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  393 bits (1009), Expect = e-109
 Identities = 198/461 (42%), Positives = 296/461 (64%), Gaps = 7/461 (1%)

Query: 11  GRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL 70
           GRL L +  A L      S Q+GYN   +N+P  ++++FYN+T+  R GE +    LT L
Sbjct: 10  GRLMLAVGGAVL-----GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64

Query: 71  WSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIII 130
           WS++V++F  GG IGS  VG  VN+FGR+ ++L  N+ + V A+LMG S++  SFE++I+
Sbjct: 65  WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124

Query: 131 SRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD 190
            R ++G+  G+++  VPMY+GE++P  LRGALG + QL I VGIL+AQ+FGL +++ N D
Sbjct: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184

Query: 191 GWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEI 250
            WP+LL +  +PA LQ ++LPF PESPR+LLI + +E  AK  L+ LRG   V  ++ E+
Sbjct: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244

Query: 251 RQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVP 310
           ++E         +++L+LFR  + R  +L  +VL   QQLSG+NA++YY+  I+  AGV 
Sbjct: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV- 303

Query: 311 EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVS 370
            +   Y T G+G VN   T  ++FVVE  GRR L L+G +       ++T ALAL + + 
Sbjct: 304 -QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLP 362

Query: 371 WMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIF 430
           WM Y+SIV +  +V    +GP PIP  ++ E+F Q  RP+A  V G  +W SNF VG+ F
Sbjct: 363 WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCF 422

Query: 431 PFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEI 471
            ++++  GPY FI+F V+ +L  I+ +  VPETK +TF EI
Sbjct: 423 QYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEI 463


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  389 bits (999), Expect = e-108
 Identities = 202/472 (42%), Positives = 295/472 (62%), Gaps = 3/472 (0%)

Query: 8   MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPL 67
           M +GR+ L+   A   A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  +
Sbjct: 10  MIQGRILLLTICA---AGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLV 66

Query: 68  TLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127
            L+WS+ VS++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+
Sbjct: 67  LLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEM 126

Query: 128 IIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLA 187
           I++ RLLVG+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL 
Sbjct: 127 IMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLG 186

Query: 188 NVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREV 247
               WP+LL    VP ALQL  LP  PESPRYLLI   D  A   AL+ LRG   +  E+
Sbjct: 187 GPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGEL 246

Query: 248 AEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSA 307
            E+ +E  A +        +LF+ R+LR Q+ S++VL    +L G +++Y YA  ++  A
Sbjct: 247 EELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKA 306

Query: 308 GVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQD 367
           GVPE  +QY   GTG+  ++    +  V+E +GRR+LL+ G+S+      + T AL LQ 
Sbjct: 307 GVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQS 366

Query: 368 TVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVG 427
           +  W  Y+++ C+ ++++   +GP+ +  +L TE+F Q +RP+A MV G++ W+    VG
Sbjct: 367 SFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVG 426

Query: 428 LIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479
           L FPFI E L  + ++ F  +C+   IY  L +PETK KTF EI++   ++N
Sbjct: 427 LGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  389 bits (998), Expect = e-108
 Identities = 199/464 (42%), Positives = 290/464 (62%)

Query: 16  VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75
           +L L    A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  + L+WS+ V
Sbjct: 19  ILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIV 78

Query: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
           S++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+I++ RLLV
Sbjct: 79  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 138

Query: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
           G+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL     WP+L
Sbjct: 139 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLL 198

Query: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDE 255
           L    VP ALQL  LP  PESPRYLLI   D  A   AL+ LRG   +  E+ E+ +E  
Sbjct: 199 LASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERA 258

Query: 256 AEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQ 315
           A +        +LF+ R+LR Q+ S++VL    +L G +++Y YA  ++  AGVPE  +Q
Sbjct: 259 ACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQ 318

Query: 316 YVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYI 375
           Y   GTG+  ++    +  V+E +GRR+LL+ G+S+      + T AL LQ +  W  Y+
Sbjct: 319 YAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYL 378

Query: 376 SIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQE 435
           ++ C+ ++++   +GP+ +  +L TE+F Q +RP+A MV G++ W+    VGL FPFI E
Sbjct: 379 AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIME 438

Query: 436 GLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479
            L  + ++ F  +C+   IY  L +PETK KTF EI++   ++N
Sbjct: 439 ALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 482


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  389 bits (998), Expect = e-108
 Identities = 199/464 (42%), Positives = 290/464 (62%)

Query: 16  VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75
           +L L    A  G +FQ+GYN++ +N+P L +Q+F NET+  RTGE + D  + L+WS+ V
Sbjct: 12  ILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIV 71

Query: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
           S++P GG  G+LL GPL    GRK +LL NNIF +  AIL G SR A SFE+I++ RLLV
Sbjct: 72  SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLV 131

Query: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
           G+ AGVS N+ PMYLGE APK LRGA+ +   +F  +GI++ Q+ GLR LL     WP+L
Sbjct: 132 GVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLL 191

Query: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDE 255
           L    VP ALQL  LP  PESPRYLLI   D  A   AL+ LRG   +  E+ E+ +E  
Sbjct: 192 LASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERA 251

Query: 256 AEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQ 315
           A +        +LF+ R+LR Q+ S++VL    +L G +++Y YA  ++  AGVPE  +Q
Sbjct: 252 ACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQ 311

Query: 316 YVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYI 375
           Y   GTG+  ++    +  V+E +GRR+LL+ G+S+      + T AL LQ +  W  Y+
Sbjct: 312 YAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYL 371

Query: 376 SIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQE 435
           ++ C+ ++++   +GP+ +  +L TE+F Q +RP+A MV G++ W+    VGL FPFI E
Sbjct: 372 AMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIME 431

Query: 436 GLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479
            L  + ++ F  +C+   IY  L +PETK KTF EI++   ++N
Sbjct: 432 ALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 475


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  387 bits (995), Expect = e-107
 Identities = 210/492 (42%), Positives = 305/492 (61%), Gaps = 9/492 (1%)

Query: 4   QDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTG-EFM 62
           +D    + R+T  L LA   A  GS  Q+GYN+  +N+P  +++Q YNET+ GR G E  
Sbjct: 11  EDGEPPQQRVTGTLVLAVFSAVLGS-LQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGP 69

Query: 63  EDFP---LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCS 119
              P   LT LW+++V++F  GG I S L+G +    GRK A+L NN+ +++   LMG +
Sbjct: 70  SSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLA 129

Query: 120 RVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQI 179
             A S+E++I+ R L+G  +G++S +VPMY+GE+AP +LRGALG + QL I +GIL+AQ+
Sbjct: 130 NAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQV 189

Query: 180 FGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRG 239
            GL +LL     WP+LLGLT +PA LQL+LLPF PESPRYL I +  E  A+K+L+ L G
Sbjct: 190 LGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTG 249

Query: 240 WDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYY 299
           W  V   +AE++ E    +    +S+L+L   R+ R  L+  +VL   QQLSG+NA++YY
Sbjct: 250 WADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYY 309

Query: 300 ADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL 359
           +  I+ +AGV +    Y T G G VN V T  +V +VE  GRR L LLG +       ++
Sbjct: 310 STSIFETAGVGQP--AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILM 367

Query: 360 TAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVH 419
           T AL L + V  M Y+SIV +  +V    +GP PIP  ++ E+F Q  RP+A  V G  +
Sbjct: 368 TVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSN 427

Query: 420 WLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479
           W SNF +G+ F ++ E +GPY F++FAV+ L   I+ FL VPET+ +TF +I+  F +  
Sbjct: 428 WTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTP 487

Query: 480 KV--SEVYPEKE 489
            +   EV P  E
Sbjct: 488 SLLEQEVKPSTE 499


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  373 bits (958), Expect = e-103
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 1   MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE 60
           MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE
Sbjct: 1   MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGE 60

Query: 61  FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR 120
           FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR
Sbjct: 61  FMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR 120

Query: 121 VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF 180
           VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF
Sbjct: 121 VATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIF 180

Query: 181 GLRNLLANVDG 191
           GLRNLLANVDG
Sbjct: 181 GLRNLLANVDG 191


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  363 bits (933), Expect = e-100
 Identities = 190/464 (40%), Positives = 282/464 (60%), Gaps = 3/464 (0%)

Query: 12  RLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLW 71
           ++T  L  A  +A  GS FQ+GYN   +N+P  ++++F N+T   +      +  LT LW
Sbjct: 5   KVTPALIFAITVATIGS-FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW 63

Query: 72  SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIIS 131
           S++V++F  GG IGS  VG  VN+FGR+ ++L  N+ ++     MG  +VA S E++I+ 
Sbjct: 64  SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILG 123

Query: 132 RLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDG 191
           RL++G+  G+ +  VPMY+GE++P  LRGA G + QL I VGILVAQIFGL  +L + + 
Sbjct: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEEL 183

Query: 192 WPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR 251
           WP+LLG T +PA LQ   LPF PESPR+LLI +K+E  AK+ LQ L G   V +++ E++
Sbjct: 184 WPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMK 243

Query: 252 QEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPE 311
            E         ++VL+LFR+ S R  ++  IVL   QQLSG+NA++YY+  I+  AGV E
Sbjct: 244 DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQE 303

Query: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSW 371
               Y T G G VN + T  ++F+VE  GRR L ++G         ++T +L L+D  + 
Sbjct: 304 P--IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNG 361

Query: 372 MPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFP 431
           M ++ I  ++ +V    +GP PIP  ++ E+F Q  RP+A  V G  +W SNF VGL+FP
Sbjct: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421

Query: 432 FIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
                LG Y FI+F    +    + F  VPET+ +TF +I + F
Sbjct: 422 SAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  350 bits (899), Expect = 1e-96
 Identities = 184/463 (39%), Positives = 277/463 (59%), Gaps = 3/463 (0%)

Query: 13  LTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWS 72
           +T  L  A  +A  GS FQ+GYN   +N+P  ++++F N+T   +      +  LT LWS
Sbjct: 30  VTPALIFAITVATIGS-FQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWS 88

Query: 73  VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
           ++V++F  GG IGS  VG  VN+FGR+ ++L  N+ +     LMG  ++A S E++I+ R
Sbjct: 89  LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGR 148

Query: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGW 192
           L++G+  G+ +  VPMY+GE++P  LRGA G + QL I +GILVAQIFGL  +L + + W
Sbjct: 149 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELW 208

Query: 193 PILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQ 252
           P+LLG T +PA LQ   LP  PESPR+LLI +K E  A + LQ L G   V +++ E++ 
Sbjct: 209 PVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKD 268

Query: 253 EDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEE 312
           E         ++VL+LFR+ S R  ++  IVL   QQLSG+NA++YY+  I+  AGV  +
Sbjct: 269 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--Q 326

Query: 313 HVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWM 372
              Y T   G VN + T  ++F+VE  GRR L ++G         ++T +L L++  + M
Sbjct: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGM 386

Query: 373 PYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPF 432
            ++ I  ++ +V    +GP PIP  ++ E+F Q  RP+A  V G  +W SNF VGL+FP 
Sbjct: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446

Query: 433 IQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
               LG Y FI+F    +    + F  VPET+ +TF +I + F
Sbjct: 447 AAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  341 bits (874), Expect = 1e-93
 Identities = 199/504 (39%), Positives = 281/504 (55%), Gaps = 37/504 (7%)

Query: 8   MKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFY--------------NET 53
           M E ++T  L    + A  GS FQ+GY++  +N+P  ++   Y              N  
Sbjct: 1   MTEDKVTGTLVFTVITAVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNY 59

Query: 54  YYGRTGEF------MEDFP--------------LTLLWSVTVSMFPFGGFIGSLLVGPLV 93
               T E       M   P              +T+LWS++VS F  GG   S   G L 
Sbjct: 60  VINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLG 119

Query: 94  NKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGEL 153
           +  GR  A+L  NI S+V A+LMG S++  S  LII  R + G+  G+ S +VPMY+GE+
Sbjct: 120 DTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEI 179

Query: 154 APKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFF 213
           AP  LRGALG   QL I  GIL++QI GL  +L N D W ILLGL+GV A LQ LLL F 
Sbjct: 180 APTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFC 239

Query: 214 PESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRS 273
           PESPRYL I+  +E  AK++L+ LRG+D V +++ E+R+E E   +   +S+++LF   S
Sbjct: 240 PESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSS 299

Query: 274 LRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAV 333
            R  +L  ++L   QQ SG+N I+YY+  I+ +AG+ +    Y T G GAVN+V T  +V
Sbjct: 300 YRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKP--VYATIGVGAVNMVFTAVSV 357

Query: 334 FVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSP 393
           F+VE  GRR L L+G S   +    ++  L L +  SWM Y+S++ +  +V    +GP P
Sbjct: 358 FLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGP 417

Query: 394 IPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTT 453
           IP  ++ E F Q  RP+A  +    +W  NF V L F +I +  GPY F +FA + L  T
Sbjct: 418 IPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFT 477

Query: 454 IYIFLIVPETKAKTFIEINQIFTK 477
           ++ F  VPETK K+F EI   F K
Sbjct: 478 LFTFFKVPETKGKSFEEIAAEFQK 501


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  153 bits (386), Expect = 4e-37
 Identities = 145/497 (29%), Positives = 228/497 (45%), Gaps = 69/497 (13%)

Query: 7   SMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFP 66
           S   GR   + A A  +      F  GY+  A+ S    +Q+             ++D  
Sbjct: 19  SAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPS----LQRA------APPAPRLDDAA 68

Query: 67  LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNI-----FSIVPAILMGCSRV 121
            +   +V       G   G +L G LV++ GRK +LL  ++     F+++ A        
Sbjct: 69  ASWFGAVVT----LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITA-------- 116

Query: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181
           A    +++  RLL G+  GV+S V P+Y+ E+A   +RG LG   QL + VGIL+A + G
Sbjct: 117 AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG 176

Query: 182 LRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQ-KKDEAAAKKALQTLRGW 240
                  V  W  L  L  VP +L LLL+ F PE+PR+LL Q ++ EA A  AL+ L G 
Sbjct: 177 W------VLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWG- 227

Query: 241 DSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA 300
                  +E   ED    A      L L R   +    +  + LM  QQLSGVNA+ +YA
Sbjct: 228 -------SEQGWEDPPIGAEQSFH-LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYA 279

Query: 301 DQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL- 359
           + I+  A   +  +  V    G + V+ T  A  +++  GRRLLL+L   + + +     
Sbjct: 280 ETIFEEAKFKDSSLASVV--VGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG 337

Query: 360 ------------TAALALQDTVSWMP--------YISIVCVISYVIGHALGPSPIPALLI 399
                       ++ +A+   VS  P        ++++  +  ++ G A+G  PIP LL+
Sbjct: 338 AYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLM 397

Query: 400 TEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY-SFIVFAVICLLTTIYIFL 458
           +EIF    +  A  +    +WL  F V   F  + E L PY +F + +  C+ + ++   
Sbjct: 398 SEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLF 457

Query: 459 IVPETKAKTFIEINQIF 475
            VPETK KT  +I   F
Sbjct: 458 CVPETKGKTLEQITAHF 474


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score =  145 bits (365), Expect = 1e-34
 Identities = 109/361 (30%), Positives = 171/361 (47%), Gaps = 28/361 (7%)

Query: 18  ALATLIAAFGS--SFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTV 75
           A   ++A F +   F +GY+   V+   LL+++                  L  LW   +
Sbjct: 79  AFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDALWQELL 123

Query: 76  SMFPFGGFIGSLLVGPLVNK-FGRKGALLFNN-IFSIVPAILMGCSRVATSFELIIISRL 133
                G    S L G  +N  FGR+ A+L  + +F+   A+L      A + E ++  RL
Sbjct: 124 VSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAA----ANNKETLLAGRL 179

Query: 134 LVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWP 193
           +VG+  G++S  VP+Y+ E++P NLRG L  +  LFIT G   A +          DGW 
Sbjct: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWR 239

Query: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR-- 251
            +LGL  VPA +Q     F PESPR+ LIQK     A++ L  +RG  ++D E   I+  
Sbjct: 240 YMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNN 298

Query: 252 -QEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVP 310
            +E+E E  +    + ++      R  L+    L   QQLSG+N I YY+  I   +GV 
Sbjct: 299 IEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVE 358

Query: 311 EEHVQ-YVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTV 369
           ++ +  ++ + T   N + T   V++VE +GRR L     +   +A  +L     L   V
Sbjct: 359 DDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQV 418

Query: 370 S 370
           S
Sbjct: 419 S 419



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 1/103 (0%)

Query: 374 YISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFI 433
           + +++ +I Y++  A G  P+P  + +EI+   +R +       ++W+ N  V L F   
Sbjct: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566

Query: 434 QEGLGPY-SFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
            E L  Y +F ++A    +  ++I+  +PETK K   EI  +F
Sbjct: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  134 bits (338), Expect = 1e-31
 Identities = 120/430 (27%), Positives = 196/430 (45%), Gaps = 47/430 (10%)

Query: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
           S+F  G   G L    L +  GRK +++F+ + S     LM     A    ++++ R L 
Sbjct: 86  SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142

Query: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
           G   G+++  +P+Y+ E+AP  +RGALG  PQL    G L     GL  LL     W  L
Sbjct: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRWL 196

Query: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD-SVDREVAEIRQED 254
                 P  + +LLL F P SPR+LL + +DE A  +AL  LRG D  V  E  +I  +D
Sbjct: 197 AVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL-RALAWLRGTDVDVHWEFEQI--QD 253

Query: 255 EAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV---PE 311
              + +  +S  +       R   +++++ +  QQL+G+  I  Y   I+ S  V   P+
Sbjct: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRL-LQQLTGITPILVYLQSIFDSTAVLLPPK 312

Query: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL------------ 359
           +    V    GAV ++    A   ++L GR++LL +  +I   A   L            
Sbjct: 313 DDAAIV----GAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLS 368

Query: 360 ---TAAL----------ALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQS 406
              TA L           L     ++  + ++  + +++G+A+G  PI  LL++E+    
Sbjct: 369 PNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLR 428

Query: 407 SRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKA 465
           +R  A  +     WL+ F +   F  +    G    F  FA ICL++ ++    VPETK 
Sbjct: 429 ARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKG 488

Query: 466 KTFIEINQIF 475
           ++  +I   F
Sbjct: 489 RSLEQIESFF 498


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  124 bits (311), Expect = 2e-28
 Identities = 114/405 (28%), Positives = 180/405 (44%), Gaps = 59/405 (14%)

Query: 76  SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
           S+F  G   G L    L +  GRK +++F+ + S     LM     A    ++++ R L 
Sbjct: 86  SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAG---AHGLWMLLLGRTLT 142

Query: 136 GICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPIL 195
           G   G+++  +P+Y+ E+AP  +RGALG  PQL    G L     GL  LL     W  L
Sbjct: 143 GFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRWL 196

Query: 196 LGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD-SVDREVAEIRQED 254
                 P  + +LLL F P SPR+LL + +DE A  +AL  LRG D  V  E  +I  +D
Sbjct: 197 AVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEAL-RALAWLRGTDVDVHWEFEQI--QD 253

Query: 255 EAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV---PE 311
              + +  +S  +       R   +++++ +  QQL+G+  I  Y   I+ S  V   P+
Sbjct: 254 NVRRQSSRVSWAEARAPHVCRPITVALLMRL-LQQLTGITPILVYLQSIFDSTAVLLPPK 312

Query: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSW 371
           +    V    GAV ++    A   ++L GR++LL                          
Sbjct: 313 DDAAIV----GAVRLLSVLIAALTMDLAGRKVLL-------------------------- 342

Query: 372 MPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFP 431
                      +V G+A+G  PI  LL++E+    +R  A  +     WL+ F +   F 
Sbjct: 343 -----------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFL 391

Query: 432 FIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
            +    G    F  FA ICL++ ++    VPETK ++  +I   F
Sbjct: 392 PVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score =  114 bits (285), Expect = 2e-25
 Identities = 82/282 (29%), Positives = 142/282 (50%), Gaps = 12/282 (4%)

Query: 73  VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
           + VS    G  + SL  G L++++GR+ A++ ++    + ++++  S    S+ ++I+ R
Sbjct: 81  MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILS---LSYTVLIVGR 137

Query: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANV-DG 191
           + +G+   +SS    +Y+ E+AP++ RG L  + +L I +GIL A I       ANV  G
Sbjct: 138 IAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY--AFANVFHG 195

Query: 192 WPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR 251
           W  + GL      LQ + + F P SPR+ L+ K  E AA K L  LR       E+  I+
Sbjct: 196 WKYMFGLVIPLGVLQAIAMYFLPPSPRF-LVMKGQEGAASKVLGRLRALSDTTEELTVIK 254

Query: 252 QEDEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV- 309
              + E    F     LFR + ++R +++  + L+   Q++G   I +YA  +  S G  
Sbjct: 255 SSLKDEYQYSF---WDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQ 311

Query: 310 PEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSI 351
             E     + G G V V+ T  A  +V+ +G +  L +G S+
Sbjct: 312 SNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSV 353



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 29/116 (25%), Positives = 65/116 (56%), Gaps = 1/116 (0%)

Query: 367 DTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTV 426
           D  +++ ++S+  ++ YV   ++G  P+P L+++EIF    R  A  +  S++W  N  +
Sbjct: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514

Query: 427 GLIFPFIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKV 481
            L F  + + +G P+   ++ ++ L + +++ + +PETK  +  +I+    K+N V
Sbjct: 515 SLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYV 570


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 99/344 (28%), Positives = 152/344 (44%), Gaps = 44/344 (12%)

Query: 16  VLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLL-WSVT 74
           VL L   ++  G    +GY +A ++   L +Q                DF L+ L     
Sbjct: 7   VLPLCASVSLLGG-LTFGYELAVISGALLPLQL---------------DFGLSCLEQEFL 50

Query: 75  VSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLL 134
           V     G  + SL+ G L++ +GRK A+L +N+  +  ++ +G   +A S   +++ R +
Sbjct: 51  VGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAV 107

Query: 135 VGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVD-GWP 193
           VG    +SS    +Y+ EL     RG L  + +  ITVGIL++  + L   LA    GW 
Sbjct: 108 VGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLS--YALNYALAGTPWGWR 165

Query: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQE 253
            + G    PA LQ L L F P           DE A  K L  L+G ++        R  
Sbjct: 166 HMFGWATAPAVLQSLSLLFLPAG--------TDETATHKDLIPLQGGEAPKLGPGRPR-- 215

Query: 254 DEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV-PE 311
                     S L LFR R ++R +    + L+  QQL+G   +  YA  I+ S G    
Sbjct: 216 ---------YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266

Query: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIA 355
                 + G GAV V  T  A+ +V+  GRR LLL G ++  ++
Sbjct: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALS 310



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 30/105 (28%), Positives = 60/105 (57%), Gaps = 1/105 (0%)

Query: 374 YISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFI 433
           + +++C++ +V   + G  P+  L+++EI+    R  AF    S +W +N  + L F  +
Sbjct: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469

Query: 434 QEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTK 477
              +G  ++F+++ +  +L   +I+L VPETK ++  EI+Q F K
Sbjct: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQK 514


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 101/424 (23%), Positives = 181/424 (42%), Gaps = 45/424 (10%)

Query: 81  GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAG 140
           G FIGS+ +G + ++FGRK  LL   + +    +LM    ++ ++  ++I RL+ G+ + 
Sbjct: 159 GFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMA---ISPTYTWMLIFRLIQGLVSK 215

Query: 141 VSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTG 200
               +  + + E   +  R  +G+  Q+  TVG+LV     L  +   +  W  L     
Sbjct: 216 AGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV-----LAGVAYALPHWRWLQFTVA 270

Query: 201 VPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTL--RGWDSVDREVAEIRQEDEAEK 258
           +P    LL     PESPR+L+ Q K+ A A + ++ +  +   S+   +  +R E+E  K
Sbjct: 271 LPNFFFLLYYWCIPESPRWLISQNKN-AEAMRIIKHIAKKNGKSLPASLQRLRLEEETGK 329

Query: 259 AAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVT 318
                S L L R   +R   +   +LM     S V  +Y     + +  G+  +++    
Sbjct: 330 KLN-PSFLDLVRTPQIRKHTM---ILMYNWFTSSV--LY---QGLIMHMGLAGDNIYLDF 380

Query: 319 AGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIV 378
             +  V     F  +  ++ +GRR        +   AC    A++ +   + W+  I I 
Sbjct: 381 FYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAAC---LASVFIPGDLQWLKII-IS 436

Query: 379 CVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNF--TVGLIFPFIQEG 436
           C+    I  A     I  L+  E++        F+    VH  S+     G+I PF+   
Sbjct: 437 CLGRMGITMAY---EIVCLVNAELY------PTFIRNLGVHICSSMCDIGGIITPFLVYR 487

Query: 437 LG----PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEI-----NQIFTKMNKVSEVYPE 487
           L         +VF V+ L+    + L++PETK K   E      N    + NK   +Y +
Sbjct: 488 LTNIWLELPLMVFGVLGLVAG-GLVLLLPETKGKALPETIEEAENMQRPRKNKEKMIYLQ 546

Query: 488 KEEL 491
            ++L
Sbjct: 547 VQKL 550


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 98/391 (25%), Positives = 170/391 (43%), Gaps = 38/391 (9%)

Query: 81  GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAG 140
           G   GSL VG   ++FGRK  LL   + + V  +LM  S    ++  +++ RLL G+ + 
Sbjct: 158 GFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSMLLFRLLQGLVSK 214

Query: 141 VSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTG 200
            +       + E      R  + ++ Q+  TVG++      L  L   +  W  L     
Sbjct: 215 GNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVA-----LTGLAYALPHWRWLQLAVS 269

Query: 201 VPAALQLLLLPFFPESPRYLLIQKKDEAAAK---KALQTLRGWDSVDREVAEIRQEDEAE 257
           +P  L LL     PESPR+LL QK++  A K      Q        D ++  + +ED  E
Sbjct: 270 LPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSL-EEDVTE 328

Query: 258 KAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYV 317
           K +   S   LFR   LR +   ++ L         +++ Y    +++ A     ++ ++
Sbjct: 329 KLSP--SFADLFRTPRLRKRTFILMYLW------FTDSVLYQGLILHMGATSGNLYLDFL 380

Query: 318 TAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISI 377
              +  V +   F A+  ++ +GR   + +   +   AC V+   + +   + W+  I I
Sbjct: 381 Y--SALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM---IFISPDLHWLNII-I 434

Query: 378 VCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFI---- 433
           +CV    I  A+    +  L+  E++    R    MV  S+  +     G+I PFI    
Sbjct: 435 MCVGRMGITIAI---QMICLVNAELYPTFVRNLGVMVCSSLCDIG----GIITPFIVFRL 487

Query: 434 QEGLGPYSFIVFAVICLLTTIYIFLIVPETK 464
           +E       I+FAV+ LL    + L++PETK
Sbjct: 488 REVWQALPLILFAVLGLLAA-GVTLLLPETK 517


>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
          Length = 556

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 87/339 (25%), Positives = 150/339 (44%), Gaps = 46/339 (13%)

Query: 73  VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
           +T ++   G   G+  +G   +++GR    L + +   V  +++     A +F + +I R
Sbjct: 156 LTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVA---FAPNFPVFVIFR 212

Query: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGW 192
            L G+    +     + + E+     R  +G+V Q+F T+GI++    G+   + N  G 
Sbjct: 213 FLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILP--GIAYFIPNWQG- 269

Query: 193 PILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR-----GWDSVDREV 247
            I L +T +P+ L LL     PESPR+L+ +KK +    KALQ LR         +    
Sbjct: 270 -IQLAIT-LPSFLFLLYYWVVPESPRWLITRKKGD----KALQILRRIAKCNGKYLSSNY 323

Query: 248 AEIRQEDEAEKAAGFISVLKLFRMRSLRWQLL-----SIIVLMGGQQLSGVNAIYYYADQ 302
           +EI   DE      F+ +++  +MR     L+     S +V  G     G+     Y D 
Sbjct: 324 SEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYID- 382

Query: 303 IYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAA 362
            +  +GV E          GA+ +++T      +E LGRRL       +  +AC V TA 
Sbjct: 383 -FFISGVVEL--------PGALLILLT------IERLGRRLPFAASNIVAGVACLV-TAF 426

Query: 363 LA-----LQDTVSWMPYISIVCV--ISYVIGHALGPSPI 394
           L      L+ TV+ +  + I     I Y++   L P+ +
Sbjct: 427 LPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTL 465


>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
          Length = 547

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 101/406 (24%), Positives = 160/406 (39%), Gaps = 33/406 (8%)

Query: 72  SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIIS 131
           S   S F  G F+G +  G L ++FGRK   L      I+ AI  G S    S+E   ++
Sbjct: 112 SAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFS---PSYEFFAVT 168

Query: 132 RLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDG 191
           R LVG+  G  S V  + L E          G +  LF  VGI    + G       +  
Sbjct: 169 RFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGY-----FIRS 223

Query: 192 WPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR 251
           W  L  L  +   +  LL  F PESPR+L  Q +   A +      +    +    +   
Sbjct: 224 WRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTH 283

Query: 252 QEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPE 311
             + + +  G  S L LFR R L    L ++ +        V ++ YY   + LSAG   
Sbjct: 284 PANRSCRETG--SFLDLFRYRVLLGHTLILMFIW------FVCSLVYYG--LTLSAGDLG 333

Query: 312 EHVQYVTAGTGAVNVVMTFCAVFVV--ELLGRRLLLLLGFSICLIACCVLTAALALQDTV 369
             +    A +G + +      ++++  +  GR+  L     +  +AC ++      +DT 
Sbjct: 334 GSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDT- 392

Query: 370 SWMPYISIVCVISYVIGHALGPSPIPALL-ITEIFLQSSRPSAFM-VGGSVHWLSNFTVG 427
                  +  V++      LG   I A   I  I+     P+    VG     + +   G
Sbjct: 393 ------GVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGG 446

Query: 428 LIFPFI---QEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIE 470
           +I PFI   +       FIVF     LT+  + L++PET     +E
Sbjct: 447 IIAPFIPSLKYVQWSLPFIVFGATG-LTSGLLSLLLPETLNSPLLE 491


>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
           sapiens]
          Length = 686

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 98/424 (23%), Positives = 171/424 (40%), Gaps = 46/424 (10%)

Query: 71  WSVTVSMFPF--GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELI 128
           W V ++ F    G   G L+ G + +  GR+  LLF+ IF ++  + +  S   T F  +
Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286

Query: 129 IISRLLVGIC-AGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLA 187
              R   G C AG+   +  + + EL P   R  + +V        + +A  F +  L A
Sbjct: 287 ---RFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASF-----VAMAGQFLMPGLAA 337

Query: 188 NVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQ-TLRGWDSVDRE 246
               W +L  L   P  L LL    FPES R+L+  ++ E+A +  L  T +   + + +
Sbjct: 338 LCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397

Query: 247 VAEI--RQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYA-DQI 303
           +  +    E E  +    + ++K+   R+L W+    IV++    L+G    + +A   +
Sbjct: 398 IKGVIPELEKELSRRPKKVCIVKVVGTRNL-WK---NIVVLCVNSLTGYGIHHCFARSMM 453

Query: 304 YLSAGVP---EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT 360
                VP     +  Y T  T ++ +V       VV  LGRR  LLL   +  +A  +  
Sbjct: 454 GHEVKVPLLENFYADYYT--TASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 511

Query: 361 AALALQDTVSWMP-----------YISIVCVISYVIGHALGPSPIPALLITEIFLQSSRP 409
             L L    S  P           +     ++     HA+G        ++  F     P
Sbjct: 512 GLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGS-------LSVFFCAEITP 564

Query: 410 SAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVI---CLLTTIYIFLIVPETKAK 466
           +    GG    L++   G++   I E      + +  +I   C L  I   L++PE++ +
Sbjct: 565 TVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQ 624

Query: 467 TFIE 470
              E
Sbjct: 625 NLPE 628


>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
           [Homo sapiens]
          Length = 560

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 111/445 (24%), Positives = 189/445 (42%), Gaps = 61/445 (13%)

Query: 81  GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR-VATSFELIIISRLLVGICA 139
           G  +G +++G   ++FGR+       + S+V    +G S  +A SF  +++ RLL G   
Sbjct: 141 GWLLGCVILGAGCDRFGRRAVF----VASLVLTTGLGASEALAASFPTLLVLRLLHG--G 194

Query: 140 GVSSNVVPMYLG--ELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLG 197
            ++  ++ +YL   EL     R A  +   LF  VG L+     L  L A V  W +L G
Sbjct: 195 TLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLL-----LPGLAALVQDWRLLQG 249

Query: 198 LTGVPAALQLLLLPF---FPESPRYLLIQKKDEAAAK------KALQTLRGWDSVDRE-- 246
           L  + + L LL   F   FPESP +LL   +   A K      +A     G  S++    
Sbjct: 250 LGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSL 309

Query: 247 --VAEIRQEDEAEKAAGFISVLKLFRMRSLRWQ---LLSIIVLMGGQQLSGVNAIYYYAD 301
               E+           + S L L R R + W+   +L    L+GG    G+ A +  + 
Sbjct: 310 ATATELTMLSARSPQPRYHSPLGLLRTR-VTWRNGLILGFSSLVGG----GIRASFRRS- 363

Query: 302 QIYLSAGVPEEHVQY-VTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT 360
              L+  VP  ++ Y + AG  A  +V     +   +  GRR +LLLG  +  +A  +L 
Sbjct: 364 ---LAPQVPTFYLPYFLEAGLEAAALVFL---LLTADCCGRRPVLLLGTMVTGLASLLLL 417

Query: 361 AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW 420
           A    Q    W   +  + V+  +   A+  S + +L   E+F     P+     G    
Sbjct: 418 A--GAQYLPGWT--VLFLSVLGLLASRAV--SALSSLFAAEVF-----PTVIRGAGLGLV 466

Query: 421 LSNFTVGLIFPFIQEGLGPYSF----IVFAVICLLTTIYIFLIVPETKAKTFIEINQIFT 476
           L    +G     +    G   F    +VFA + +L  + + L++PE++++   +  Q   
Sbjct: 467 LGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCV-LLLPESRSRGLPQSLQDAD 525

Query: 477 KMNK--VSEVYPEKEELKELPPVTS 499
           ++ +  +    P ++ L  LPP  S
Sbjct: 526 RLRRSPLLRGRPRQDHLPLLPPSNS 550


>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
           [Homo sapiens]
          Length = 558

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 112/454 (24%), Positives = 192/454 (42%), Gaps = 79/454 (17%)

Query: 81  GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSR-VATSFELIIISRLLVGICA 139
           G  +G +++G   ++FGR+       + S+V    +G S  +A SF  +++ RLL G   
Sbjct: 139 GWLLGCVILGAGCDRFGRRAVF----VASLVLTTGLGASEALAASFPTLLVLRLLHG--G 192

Query: 140 GVSSNVVPMYLG--ELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLG 197
            ++  ++ +YL   EL     R A  +   LF  VG L+     L  L A V  W +L G
Sbjct: 193 TLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLL-----LPGLAALVQDWRLLQG 247

Query: 198 LTGVPAALQLLLLPF---FPESPRYLLIQKKDEAAAK------KALQTLRGWDSVDRE-- 246
           L  + + L LL   F   FPESP +LL   +   A K      +A     G  S++    
Sbjct: 248 LGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSL 307

Query: 247 --VAEIRQEDEAEKAAGFISVLKLFRMRSLRWQ---LLSIIVLMGGQQLSGVNAIYYYAD 301
               E+           + S L L R R + W+   +L    L+GG    G+ A +  + 
Sbjct: 308 ATATELTMLSARSPQPRYHSPLGLLRTR-VTWRNGLILGFSSLVGG----GIRASFRRS- 361

Query: 302 QIYLSAGVPEEHVQY-VTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT 360
              L+  VP  ++ Y + AG  A  +V     +   +  GRR +LLLG  +  +A  +L 
Sbjct: 362 ---LAPQVPTFYLPYFLEAGLEAAALVFL---LLTADCCGRRPVLLLGTMVTGLASLLLL 415

Query: 361 AALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHW 420
           A    Q    W   +  + V+  +   A+  S + +L   E+F     P+     G    
Sbjct: 416 A--GAQYLPGWT--VLFLSVLGLLASRAV--SALSSLFAAEVF-----PTVIRGAG---- 460

Query: 421 LSNFTVGLIF--PFIQEGLGPYSF-----------IVFAVICLLTTIYIFLIVPETKAKT 467
                +GL+    F+ +  GP              +VFA + +L  + + L++PE++++ 
Sbjct: 461 -----LGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCV-LLLPESRSRG 514

Query: 468 FIEINQIFTKMNK--VSEVYPEKEELKELPPVTS 499
             +  Q   ++ +  +    P ++ L  LPP  S
Sbjct: 515 LPQSLQDADRLRRSPLLRGRPRQDHLPLLPPSNS 548



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 14  TLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSV 73
           T+V  LA+L+   G+ +  G+ V  ++   LL  +  +      +  F  +   T++   
Sbjct: 404 TMVTGLASLLLLAGAQYLPGWTVLFLSVLGLLASRAVSAL----SSLFAAEVFPTVIRGA 459

Query: 74  TVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGC 118
            + +    GF+G    GPL    GR+G  L   +F+ +  + + C
Sbjct: 460 GLGLVLGAGFLGQA-AGPLDTLHGRQGFFLQQVVFASLAVLALLC 503


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 90/315 (28%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 76  SMFPFGG-FIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLL 134
           S F F G  +G++  G L ++FGR+  LL   + ++V  +    S  + S+ +  I+R L
Sbjct: 148 STFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGL---ASAASVSYVMFAITRTL 204

Query: 135 VGIC-AGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWP 193
            G   AG +  V+P+ L  L  ++ R   GV+   F T G+++  + G       +  W 
Sbjct: 205 TGSALAGFTIIVMPLELEWLDVEH-RTVAGVLSSTFWTGGVMLLALVGYL-----IRDWR 258

Query: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAE--IR 251
            LL    +P A  +L L + PES R+LL Q   + A +  L   R      R V E    
Sbjct: 259 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCAR---LNGRPVCEDSFS 315

Query: 252 QEDEAEKAAG-----FISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLS 306
           QE  ++ AAG       S L LFR   LR   L  +V+       GVN  YY        
Sbjct: 316 QEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVW-----FGVNFSYYGLSLDVSG 370

Query: 307 AGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLL---LLLGFSICLIACCVLTAAL 363
            G+     Q +    GAV +         V   GRRL     LLG      A    T  L
Sbjct: 371 LGLNVYQTQLL---FGAVELPSKLLVYLSVRYAGRRLTQAGTLLG-----TALAFGTRLL 422

Query: 364 ALQDTVSWMPYISIV 378
              D  SW   ++++
Sbjct: 423 VSSDMKSWSTVLAVM 437


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 90/315 (28%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 76  SMFPFGG-FIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLL 134
           S F F G  +G++  G L ++FGR+  LL   + ++V  +    S  + S+ +  I+R L
Sbjct: 146 STFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGL---ASAASVSYVMFAITRTL 202

Query: 135 VGIC-AGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWP 193
            G   AG +  V+P+ L  L  ++ R   GV+   F T G+++  + G       +  W 
Sbjct: 203 TGSALAGFTIIVMPLELEWLDVEH-RTVAGVLSSTFWTGGVMLLALVGYL-----IRDWR 256

Query: 194 ILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAE--IR 251
            LL    +P A  +L L + PES R+LL Q   + A +  L   R      R V E    
Sbjct: 257 WLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCAR---LNGRPVCEDSFS 313

Query: 252 QEDEAEKAAG-----FISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLS 306
           QE  ++ AAG       S L LFR   LR   L  +V+       GVN  YY        
Sbjct: 314 QEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVW-----FGVNFSYYGLSLDVSG 368

Query: 307 AGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLL---LLLGFSICLIACCVLTAAL 363
            G+     Q +    GAV +         V   GRRL     LLG      A    T  L
Sbjct: 369 LGLNVYQTQLL---FGAVELPSKLLVYLSVRYAGRRLTQAGTLLG-----TALAFGTRLL 420

Query: 364 ALQDTVSWMPYISIV 378
              D  SW   ++++
Sbjct: 421 VSSDMKSWSTVLAVM 435


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 96/436 (22%), Positives = 169/436 (38%), Gaps = 63/436 (14%)

Query: 71  WSVTV--SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELI 128
           W V +  +M  FG  + S+L G L +++GR   LL + ++    ++L   +  A S+   
Sbjct: 84  WQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLL---TSFAPSYIWF 140

Query: 129 IISRLLVGICAGVSSNVVPMYLG-ELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLA 187
           +  R +VG   GVS +   + +  E  P   RG +  + Q+F   G L+  I GL +++ 
Sbjct: 141 VFLRTMVG--CGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVII 196

Query: 188 NVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREV 247
              GW  L+ +  +P  + ++   F PES R+           + AL TL     ++R V
Sbjct: 197 PTIGWRWLIRVASIPGIILIVAFKFIPESARF----NVSTGNTRAALATLERVAKMNRSV 252

Query: 248 AEIRQ--EDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIY- 304
               +  E   EK   F  +L    +R+     L I V+  G   +    I   A+ +  
Sbjct: 253 MPEGKLVEPVLEKRGRFADLLDAKYLRT----TLQIWVIWLGISFAYYGVILASAELLER 308

Query: 305 -LSAGVPEEHVQYVTAGTGAVNVVMTFCAVFV------------------------VELL 339
            L  G   +    VT G    +    +C +F                         +  L
Sbjct: 309 DLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFL 368

Query: 340 GRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLI 399
           GRRL      S+ +   C     L L    S    I  + ++  ++        I     
Sbjct: 369 GRRL------SLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVYI---YT 419

Query: 400 TEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFI----VFAVICLLTTIY 455
            E++  + R       GS+  +      ++ PFI + L   S +    +F+ +C++  I 
Sbjct: 420 AEVYPTTMRALGMGTSGSLCRIG----AMVAPFISQVLMSASILGALCLFSSVCVVCAIS 475

Query: 456 IFLIVPETKAKTFIEI 471
            F +  ETK +   +I
Sbjct: 476 AFTLPIETKGRALQQI 491


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 73/303 (24%), Positives = 131/303 (43%), Gaps = 26/303 (8%)

Query: 81  GGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAG 140
           G   GSL VG   ++FGRK  LL   + + V  +LM  S    ++  +++ RLL G+ + 
Sbjct: 158 GFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFS---PNYMSMLLFRLLQGLVSK 214

Query: 141 VSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTG 200
            +       + E      R  + ++ Q+  TVG++      L  L   +  W  L     
Sbjct: 215 GNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVA-----LTGLAYALPHWRWLQLAVS 269

Query: 201 VPAALQLLLLPFFPESPRYLLIQKKDEAAAK---KALQTLRGWDSVDREVAEIRQEDEAE 257
           +P  L LL     PESPR+LL QK++  A K      Q        D ++  + +ED  E
Sbjct: 270 LPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSL-EEDVTE 328

Query: 258 KAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYV 317
           K +   S   LFR   LR +   ++ L         +++ Y    +++ A     ++ ++
Sbjct: 329 KLSP--SFADLFRTPRLRKRTFILMYLW------FTDSVLYQGLILHMGATSGNLYLDFL 380

Query: 318 TAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYISI 377
              +  V +   F A+  ++ +GR   + +   +   AC V+   + +   + W+  I I
Sbjct: 381 Y--SALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM---IFISPDLHWLNII-I 434

Query: 378 VCV 380
           +CV
Sbjct: 435 MCV 437


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,730,098
Number of Sequences: 37866
Number of extensions: 687937
Number of successful extensions: 2149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2036
Number of HSP's gapped (non-prelim): 80
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.