BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507011 glucose transporter 4 [Homo sapiens] (509 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507011 glucose transporter 4 [Homo sapiens] 992 0.0 gi|166795299 solute carrier family 2 (facilitated glucose transp... 641 0.0 gi|5902090 solute carrier family 2 (facilitated glucose transpor... 559 e-159 gi|23592238 glucose transporter 14 [Homo sapiens] 541 e-154 gi|4557851 solute carrier family 2 (facilitated glucose transpor... 520 e-147 gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 387 e-107 gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 382 e-106 gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 339 4e-93 gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 339 4e-93 gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 315 5e-86 gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 312 4e-85 gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 312 4e-85 gi|21361449 solute carrier family 2 (facilitated glucose transpo... 191 2e-48 gi|223029432 solute carrier family 2 (facilitated glucose transp... 161 1e-39 gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 160 3e-39 gi|223029430 solute carrier family 2 (facilitated glucose transp... 155 1e-37 gi|203098995 solute carrier family 2 (facilitated glucose transp... 152 7e-37 gi|21553331 solute carrier family 2 (facilitated glucose transpo... 130 2e-30 gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 108 9e-24 gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 60 5e-09 gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 57 4e-08 gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 56 7e-08 gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 56 9e-08 gi|213021148 SVOP-like isoform 1 [Homo sapiens] 55 2e-07 gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 51 2e-06 gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 50 6e-06 gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 49 8e-06 gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 49 8e-06 gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 49 1e-05 gi|24308167 SV2 related protein [Homo sapiens] 49 1e-05 >gi|4507011 glucose transporter 4 [Homo sapiens] Length = 509 Score = 992 bits (2564), Expect = 0.0 Identities = 509/509 (100%), Positives = 509/509 (100%) Query: 1 MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW 60 MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW Sbjct: 1 MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW 60 Query: 61 LGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV 120 LGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV Sbjct: 61 LGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV 120 Query: 121 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI 180 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI Sbjct: 121 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI 180 Query: 181 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA 240 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA Sbjct: 181 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA 240 Query: 241 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL 300 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL Sbjct: 241 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL 300 Query: 301 SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM 360 SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM Sbjct: 301 SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM 360 Query: 361 CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM 420 CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM Sbjct: 361 CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM 420 Query: 421 AVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS 480 AVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS Sbjct: 421 AVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS 480 Query: 481 AAFHRTPSLLEQEVKPSTELEYLGPDEND 509 AAFHRTPSLLEQEVKPSTELEYLGPDEND Sbjct: 481 AAFHRTPSLLEQEVKPSTELEYLGPDEND 509 >gi|166795299 solute carrier family 2 (facilitated glucose transporter), member 1 [Homo sapiens] Length = 492 Score = 641 bits (1653), Expect = 0.0 Identities = 323/493 (65%), Positives = 395/493 (80%), Gaps = 5/493 (1%) Query: 14 EPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73 EP +++TG L+LAV AVLGSLQFGYN GVINAPQKVIE+ YN+TW+ R G SI Sbjct: 2 EPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYG----ESIL 57 Query: 74 PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133 P TLTTLW+LSVAIFSVGGMI SF +G+ GR+ +ML+ N+LA + LMG + Sbjct: 58 PTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGK 117 Query: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193 S+EMLILGRF+IG Y GLT+G VPMYVGE++PT LRGALGTL+QL IV+GILIAQV GL+ Sbjct: 118 SFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLD 177 Query: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253 S++G LWPLLL + +PALLQ ++LPFCPESPR+L I +N E A+ LK+L G ADV Sbjct: 178 SIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADV 237 Query: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313 + L E+K+E R++ RE+ +++L+L S +RQP++IAVVLQLSQQLSGINAVFYYSTSI Sbjct: 238 THDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSI 297 Query: 314 FETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLL 373 FE AGV QP YATIG+G+VNT FT+VS+ +VERAGRRTLHL+GLAGM GCAILMT+AL L Sbjct: 298 FEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALAL 357 Query: 374 LERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFI 433 LE++P MSY+SIVAIFGFVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAGFSNWTSNFI Sbjct: 358 LEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFI 417 Query: 434 IGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQE 493 +GM FQYV + GPYVF++F VLL+ FFIFT+ +VPET+GRTFD+I++ F R + + Sbjct: 418 VGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF-RQGGASQSD 476 Query: 494 VKPSTELEYLGPD 506 P LG D Sbjct: 477 KTPEELFHPLGAD 489 >gi|5902090 solute carrier family 2 (facilitated glucose transporter), member 3 [Homo sapiens] Length = 496 Score = 559 bits (1440), Expect = e-159 Identities = 284/466 (60%), Positives = 356/466 (76%), Gaps = 4/466 (0%) Query: 18 QRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTL 77 Q+VT L+ A+ A +GS QFGYN GVINAP+K+I++ N+T L +G PS + L Sbjct: 4 QKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKT-LTDKGNAPPSEV---LL 59 Query: 78 TTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEM 137 T+LW+LSVAIFSVGGMI SF +G+ GR+ +ML+ N+LAV GG MGL A S EM Sbjct: 60 TSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEM 119 Query: 138 LILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG 197 LILGR +IG + GL +G VPMY+GEI+PT LRGA GTLNQL IV+GIL+AQ+ GLE +LG Sbjct: 120 LILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILG 179 Query: 198 TASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVL 257 + LWPLLLG T+LPA+LQ LPFCPESPR+L I + E A++ L+RL G DVS + Sbjct: 180 SEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDI 239 Query: 258 AELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETA 317 E+KDE ++ +E+ +++L+L ++RQP+II++VLQLSQQLSGINAVFYYST IF+ A Sbjct: 240 QEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA 299 Query: 318 GVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERV 377 GV +P YATIGAGVVNT+FT+VS+ LVERAGRRTLH++GL GM C+ LMTV+LLL + Sbjct: 300 GVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNY 359 Query: 378 PAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMG 437 MS+V I AI FVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAG SNWTSNF++G+ Sbjct: 360 NGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLL 419 Query: 438 FQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483 F A +G YVF++F L+ F FTF +VPETRGRTF+ I+ AF Sbjct: 420 FPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465 >gi|23592238 glucose transporter 14 [Homo sapiens] Length = 520 Score = 541 bits (1395), Expect = e-154 Identities = 280/470 (59%), Positives = 348/470 (74%), Gaps = 4/470 (0%) Query: 14 EPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73 +P VT L+ A+ A +GS QFGYN GVINAP+ +I++ N+T L + PS + Sbjct: 24 KPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKT-LTDKANAPPSEV- 81 Query: 74 PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133 LT LW+LSVAIFSVGGMI SF +G+ GR+ +ML+ N+LA GG LMGL A Sbjct: 82 --LLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAE 139 Query: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193 S EMLILGR +IG + GL +G VPMY+GEI+PT LRGA GTLNQL IVIGIL+AQ+ GLE Sbjct: 140 SVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLE 199 Query: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253 +LG+ LWP+LLG T+LPA+LQ LP CPESPR+L I + E A + L+RL G DV Sbjct: 200 LILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV 259 Query: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313 S + E+KDE ++ +E+ +++L+L ++RQP+II++VLQLSQQLSGINAVFYYST I Sbjct: 260 SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 319 Query: 314 FETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLL 373 F+ AGV QP YATI AGVVNT+FTL+S+ LVERAGRRTLH++GL GM C+ LMTV+LLL Sbjct: 320 FKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 379 Query: 374 LERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFI 433 MS+V I AI FVA FEIGPGPIPWFIVAELFSQGPRPAAMAVAG SNWTSNF+ Sbjct: 380 KNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL 439 Query: 434 IGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483 +G+ F A +G YVF++F L+ F FTF +VPETRGRTF+ I+ AF Sbjct: 440 VGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489 >gi|4557851 solute carrier family 2 (facilitated glucose transporter), member 2 [Homo sapiens] Length = 524 Score = 520 bits (1340), Expect = e-147 Identities = 273/521 (52%), Positives = 368/521 (70%), Gaps = 31/521 (5%) Query: 17 QQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNET-------------WLGR 63 + +VTGTLV V +AVLGS QFGY+IGVINAPQ+VI Y ++ Sbjct: 3 EDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVIN 62 Query: 64 QGPEGP----SSIPPGT-------------LTTLWALSVAIFSVGGMISSFLIGIISQWL 106 E P S P T +T LW+LSV+ F+VGGM +SF G + L Sbjct: 63 STDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTL 122 Query: 107 GRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPT 166 GR +AMLV N+L+++G LMG + S+ ++I GR + G Y GL SGLVPMY+GEIAPT Sbjct: 123 GRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPT 182 Query: 167 HLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPES 226 LRGALGT +QLAIV GILI+Q++GLE +LG LW +LLGL+ + A+LQ +LL FCPES Sbjct: 183 ALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPES 242 Query: 227 PRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQ 286 PRYLYI + E A++SLKRL G+ DV+ + E++ E+ + E+ +S++QL + ++RQ Sbjct: 243 PRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQ 302 Query: 287 PLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVER 346 P+++A++L ++QQ SGIN +FYYSTSIF+TAG+ +P YATIG G VN VFT VSV LVE+ Sbjct: 303 PILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEK 362 Query: 347 AGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFI 406 AGRR+L L+G++GM CAI M+V L+LL + MSYVS++AIF FV+FFEIGPGPIPWF+ Sbjct: 363 AGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFM 422 Query: 407 VAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFL 466 VAE FSQGPRPAA+A+A FSNWT NFI+ + FQY+A+ GPYVF LFA +LL F +FTF Sbjct: 423 VAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFF 482 Query: 467 RVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDE 507 +VPET+G++F++I+A F + + K + E+++LG E Sbjct: 483 KVPETKGKSFEEIAAEFQKKSGSAHRP-KAAVEMKFLGATE 522 >gi|4507013 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 1 [Homo sapiens] Length = 501 Score = 387 bits (995), Expect = e-107 Identities = 210/492 (42%), Positives = 305/492 (61%), Gaps = 9/492 (1%) Query: 11 EDGEPPQQRVTGTLVLAVFSAVLGS-LQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGP 69 +D + R+T L LA A GS Q+GYN+ +N+P +++Q YNET+ GR G E Sbjct: 4 QDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTG-EFM 62 Query: 70 SSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLA 129 P LT LW+++V++F GG I S L+G + GRK A+L NN+ +++ LMG + Sbjct: 63 EDFP---LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCS 119 Query: 130 NAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQV 189 A S+E++I+ R L+G +G++S +VPMY+GE+AP +LRGALG + QL I +GIL+AQ+ Sbjct: 120 RVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQI 179 Query: 190 LGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTG 249 GL +LL WP+LLGLT +PA LQL+LLPF PESPRYL I + E A+K+L+ L G Sbjct: 180 FGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRG 239 Query: 250 WADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYY 309 W V +AE++ E + +S+L+L R+ R L+ +VL QQLSG+NA++YY Sbjct: 240 WDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYY 299 Query: 310 STSIFETAGVGQP--AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILM 367 + I+ +AGV + Y T G G VN V T +V +VE GRR L LLG + ++ Sbjct: 300 ADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVL 359 Query: 368 TVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSN 427 T AL L + V M Y+SIV + +V +GP PIP ++ E+F Q RP+A V G + Sbjct: 360 TAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVH 419 Query: 428 WTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTP 487 W SNF +G+ F ++ E +GPY F++FAV+ L I+ FL VPET+ +TF +I+ F + Sbjct: 420 WLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMN 479 Query: 488 SLLEQEVKPSTE 499 + EV P E Sbjct: 480 KV--SEVYPEKE 489 >gi|134053883 intestinal facilitative glucose transporter 7 [Homo sapiens] Length = 512 Score = 382 bits (982), Expect = e-106 Identities = 202/497 (40%), Positives = 311/497 (62%), Gaps = 14/497 (2%) Query: 11 EDGEPP-----QQRVTGTLVLAVFSAVLGS-LQFGYNIGVINAPQKVIEQSYNETWLGRQ 64 E G PP + R+ TL+LA SA GS Q+GYN+ V+N P KV + YNET+ R Sbjct: 5 EAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERH 64 Query: 65 GPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGS 124 + + LW+ +V++F +GG++ S L+G++ GRK +L+NN+ A++ Sbjct: 65 ATFMDGKL----MLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAI 120 Query: 125 LMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGI 184 LMG++ A ++E+++ R ++G +G++ +PMY+GE+AP +LRG +GT+ ++ +++G+ Sbjct: 121 LMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV 180 Query: 185 LIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSL 244 +AQ+ L+++LG + WP+LL LT +PALLQL+ LPF PESPRY I + E AR++L Sbjct: 181 FLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQAL 240 Query: 245 KRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGIN 304 +RL G D+ L +++ E R E LS+L L R+ R L+ +VL QQLSGIN Sbjct: 241 RRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300 Query: 305 AVFYYSTSIFETAGV--GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCG 362 A+ YY+ +I+ +AGV Y T+G+GVVN V T+ S +LVER GRR L L G G+CG Sbjct: 301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGY-GICG 359 Query: 363 CA-ILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMA 421 A +++TV LL RVP +SY+ I+ +F ++A IGP P+P + E+F Q R AA Sbjct: 360 SACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFM 419 Query: 422 VAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISA 481 V G +W +NFIIG F + EA+G Y F++FA + L I+ ++ +PET+G+TF +I+ Sbjct: 420 VDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINR 479 Query: 482 AFHRTPSLLEQEVKPST 498 F + + E K T Sbjct: 480 IFAKRNRVKLPEEKEET 496 >gi|47933389 solute carrier family 2, member 9 protein isoform 2 [Homo sapiens] Length = 511 Score = 339 bits (869), Expect = 4e-93 Identities = 183/475 (38%), Positives = 283/475 (59%), Gaps = 8/475 (1%) Query: 24 LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83 LV ++ A S +GYN+ V+NAP I+ YNE+W R G I P TLT LW++ Sbjct: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHG----RPIDPDTLTLLWSV 83 Query: 84 SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143 +V+IF++GG++ + ++ +I + LGRK +L NN A+ LM + A ++EMLI+GRF Sbjct: 84 TVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143 Query: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203 ++G G+ ++PMY+ EI+P +RG+LG + + I IG+ Q+LGL LLG S WP Sbjct: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203 Query: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263 L G+ V+PA++QL+ LPF P+SPRYL + ++ E A K+ + G ADVS + E+ E Sbjct: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAE 263 Query: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV--GQ 321 R R +S+L+LL + R ++ +V QL G+NA+++Y+ SIF AG+ + Sbjct: 264 SRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK 323 Query: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAI-LMTVALLLLERVPAM 380 Y T+ G + T+ + S L++E GRR L L+G G+ G +T+ L L + P + Sbjct: 324 IPYVTLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWV 382 Query: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Y+SIV I +A F GPG IP+ + E F Q RPAA +AG NW SNF +G+ F + Sbjct: 383 PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPF 442 Query: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVK 495 + +++ Y FL+FA + + I+ + +PET+ RT+ +IS AF + E K Sbjct: 443 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497 >gi|47933387 solute carrier family 2, member 9 protein isoform 1 [Homo sapiens] Length = 540 Score = 339 bits (869), Expect = 4e-93 Identities = 183/475 (38%), Positives = 283/475 (59%), Gaps = 8/475 (1%) Query: 24 LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83 LV ++ A S +GYN+ V+NAP I+ YNE+W R G I P TLT LW++ Sbjct: 57 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHG----RPIDPDTLTLLWSV 112 Query: 84 SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143 +V+IF++GG++ + ++ +I + LGRK +L NN A+ LM + A ++EMLI+GRF Sbjct: 113 TVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 172 Query: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203 ++G G+ ++PMY+ EI+P +RG+LG + + I IG+ Q+LGL LLG S WP Sbjct: 173 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 232 Query: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263 L G+ V+PA++QL+ LPF P+SPRYL + ++ E A K+ + G ADVS + E+ E Sbjct: 233 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAE 292 Query: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV--GQ 321 R R +S+L+LL + R ++ +V QL G+NA+++Y+ SIF AG+ + Sbjct: 293 SRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK 352 Query: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAI-LMTVALLLLERVPAM 380 Y T+ G + T+ + S L++E GRR L L+G G+ G +T+ L L + P + Sbjct: 353 IPYVTLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWV 411 Query: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Y+SIV I +A F GPG IP+ + E F Q RPAA +AG NW SNF +G+ F + Sbjct: 412 PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPF 471 Query: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVK 495 + +++ Y FL+FA + + I+ + +PET+ RT+ +IS AF + E K Sbjct: 472 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526 >gi|190684655 glucose transporter protein 10 isoform a [Homo sapiens] Length = 503 Score = 315 bits (808), Expect = 5e-86 Identities = 181/497 (36%), Positives = 279/497 (56%), Gaps = 16/497 (3%) Query: 16 PQQRVTGTLVLAVFSA--VLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIP 73 P+ ++ G ++L A + G+ QFGYN+ +INAP I++ NETW R G +P Sbjct: 11 PRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLP 66 Query: 74 PGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA 133 + +W+L V+++ +GG+ + L G ++ LGRK+++LVNN+ V L G + A Sbjct: 67 DHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAG 126 Query: 134 SYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLE 193 S+EM++LGR L+G +G++ + PMY+GE AP LRGA+ + + +GI++ QV+GL Sbjct: 127 SFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLR 186 Query: 194 SLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV 253 LLG WPLLL ++P LQL LP PESPRYL I +L+RL G D+ Sbjct: 187 ELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDL 246 Query: 254 SGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSI 313 +G L EL++E+ + R +L R R+ + VVL + +L G ++V+ Y++S+ Sbjct: 247 AGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSV 306 Query: 314 FETAGVGQP--AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVAL 371 F AGV + YA IG G + +VS +++ER GRR L + G + M + TVAL Sbjct: 307 FRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVAL 366 Query: 372 LLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSN 431 L P Y+++ IF F+ F IGP + + ELF Q RPAA V G W Sbjct: 367 CLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIML 426 Query: 432 FIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT----- 486 ++G+GF ++ EA+ ++++ F + + I+T L +PET+G+TF +IS HR Sbjct: 427 ILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRR 486 Query: 487 ---PSLLEQEVKPSTEL 500 P+ EV STEL Sbjct: 487 AQGPTWRSLEVIQSTEL 503 >gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] Length = 496 Score = 312 bits (800), Expect = 4e-85 Identities = 180/488 (36%), Positives = 276/488 (56%), Gaps = 15/488 (3%) Query: 24 LVLAVFSAVLG-SLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWA 82 L+L + +A +G + QFGYN+ +INAP I++ NETW R G +P + +W+ Sbjct: 13 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLPDHLVLLMWS 68 Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142 L V+++ +GG+ + L G ++ LGRK+++LVNN+ V L G + A S+EM++LGR Sbjct: 69 LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 128 Query: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202 L+G +G++ + PMY+GE AP LRGA+ + + +GI++ QV+GL LLG W Sbjct: 129 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 188 Query: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKD 262 PLLL ++P LQL LP PESPRYL I +L+RL G D++G L EL++ Sbjct: 189 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEE 248 Query: 263 EKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQP 322 E+ + R +L R R+ + VVL + +L G ++V+ Y++S+F AGV + Sbjct: 249 ERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 308 Query: 323 --AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAM 380 YA IG G + +VS +++ER GRR L + G + M + TVAL L P Sbjct: 309 KIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWT 368 Query: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Y+++ IF F+ F IGP + + ELF Q RPAA V G W ++G+GF + Sbjct: 369 LYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPF 428 Query: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT--------PSLLEQ 492 + EA+ ++++ F + + I+T L +PET+G+TF +IS HR P+ Sbjct: 429 IMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTWRSL 488 Query: 493 EVKPSTEL 500 EV STEL Sbjct: 489 EVIQSTEL 496 >gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] Length = 499 Score = 312 bits (800), Expect = 4e-85 Identities = 180/488 (36%), Positives = 276/488 (56%), Gaps = 15/488 (3%) Query: 24 LVLAVFSAVLG-SLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWA 82 L+L + +A +G + QFGYN+ +INAP I++ NETW R G +P + +W+ Sbjct: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTG----EPLPDHLVLLMWS 71 Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142 L V+++ +GG+ + L G ++ LGRK+++LVNN+ V L G + A S+EM++LGR Sbjct: 72 LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131 Query: 143 FLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202 L+G +G++ + PMY+GE AP LRGA+ + + +GI++ QV+GL LLG W Sbjct: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191 Query: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKD 262 PLLL ++P LQL LP PESPRYL I +L+RL G D++G L EL++ Sbjct: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEE 251 Query: 263 EKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQP 322 E+ + R +L R R+ + VVL + +L G ++V+ Y++S+F AGV + Sbjct: 252 ERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311 Query: 323 --AYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAM 380 YA IG G + +VS +++ER GRR L + G + M + TVAL L P Sbjct: 312 KIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWT 371 Query: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Y+++ IF F+ F IGP + + ELF Q RPAA V G W ++G+GF + Sbjct: 372 LYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPF 431 Query: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRT--------PSLLEQ 492 + EA+ ++++ F + + I+T L +PET+G+TF +IS HR P+ Sbjct: 432 IMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTWRSL 491 Query: 493 EVKPSTEL 500 EV STEL Sbjct: 492 EVIQSTEL 499 >gi|21361449 solute carrier family 2 (facilitated glucose transporter), member 8 [Homo sapiens] Length = 477 Score = 191 bits (484), Expect = 2e-48 Identities = 150/498 (30%), Positives = 243/498 (48%), Gaps = 58/498 (11%) Query: 8 IGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPE 67 +G G P+ R + LA F+A LG L FG+ +G + ++ R P Sbjct: 13 LGPPGGSAPRGR---RVFLAAFAAALGPLSFGFALGYSSPAIPSLQ---------RAAPP 60 Query: 68 GPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMG 127 P + + A+ + GG++ +L+ GRK ++L+ +V V G +++ Sbjct: 61 APR-LDDAAASWFGAVVTLGAAAGGVLGGWLV----DRAGRKLSLLLCSVPFVAGFAVI- 114 Query: 128 LANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIA 187 AA ML+ GR L G G+ S + P+Y+ EIA +RG LG+ QL +V+GIL+A Sbjct: 115 --TAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA 172 Query: 188 QVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRL 247 L G W L L +P L L+L+ F PE+PR+L + Q+ A +L+ L Sbjct: 173 Y------LAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFL-LTQHRRQEAMAALRFL 225 Query: 248 TGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVF 307 W G +D E+ L+LL+ G +P II V L QQLSG+NAV Sbjct: 226 --WGSEQG----WEDPPIGAEQSFHLALLRQPGIY---KPFIIGVSLMAFQQLSGVNAVM 276 Query: 308 YYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLL------------ 355 +Y+ +IFE A + A++ GV+ +FT V+ L+++RAGRR L +L Sbjct: 277 FYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAF 336 Query: 356 ---------GLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFI 406 G AI V+ ++ ++++++ ++ F+A F +G GPIPW + Sbjct: 337 GAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLL 396 Query: 407 VAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPY-VFLLFAVLLLGFFIFTF 465 ++E+F + A + +NW F++ F + E + PY F L + + +FT Sbjct: 397 MSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTL 456 Query: 466 LRVPETRGRTFDQISAAF 483 VPET+G+T +QI+A F Sbjct: 457 FCVPETKGKTLEQITAHF 474 >gi|223029432 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 1 [Homo sapiens] Length = 507 Score = 161 bits (407), Expect = 1e-39 Identities = 141/487 (28%), Positives = 225/487 (46%), Gaps = 57/487 (11%) Query: 26 LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV 85 LA F+AVLG+ FGY + + +E+S + P LT A Sbjct: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLD---------------PDLHLTKSQASWF 84 Query: 86 -AIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFL 144 ++F++G I++ LGRK +++ + V + G +LM A ML+LGR L Sbjct: 85 GSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTL 141 Query: 145 IGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPL 204 G GLT+ +P+YV EIAP +RGALG QL V G L LGL LL W Sbjct: 142 TGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRW 195 Query: 205 LLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGW-ADVSGVLAELKDE 263 L P L+ ++LL F P SPR+L + + + A ++L L G DV +++D Sbjct: 196 LAVAGEAPVLIMILLLSFMPNSPRFL-LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN 254 Query: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPA 323 R+ + +S + R P+ +A++++L QQL+GI + Y SIF++ V P Sbjct: 255 VRR--QSSRVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPP 311 Query: 324 YATIG-AGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLER------ 376 G V + L++ L ++ AGR+ L + A M + + + + R Sbjct: 312 KDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNS 371 Query: 377 -----------------VPA--MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRP 417 PA ++ V ++A F+ + +G GPI W +++E+ R Sbjct: 372 TAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARG 431 Query: 418 AAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYV-FLLFAVLLLGFFIFTFLRVPETRGRTF 476 A + ++W + F++ F V G V F FA + L +FT VPET+GR+ Sbjct: 432 VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSL 491 Query: 477 DQISAAF 483 +QI + F Sbjct: 492 EQIESFF 498 >gi|207447703 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 2 [Homo sapiens] Length = 244 Score = 160 bits (404), Expect = 3e-39 Identities = 82/187 (43%), Positives = 123/187 (65%), Gaps = 5/187 (2%) Query: 11 EDGEPPQQRVTGTLVLAVFSAVLGS-LQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGP 69 +D + R+T L LA A GS Q+GYN+ +N+P +++Q YNET+ GR G E Sbjct: 4 QDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTG-EFM 62 Query: 70 SSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLA 129 P LT LW+++V++F GG I S L+G + GRK A+L NN+ +++ LMG + Sbjct: 63 EDFP---LTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCS 119 Query: 130 NAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQV 189 A S+E++I+ R L+G +G++S +VPMY+GE+AP +LRGALG + QL I +GIL+AQ+ Sbjct: 120 RVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQI 179 Query: 190 LGLESLL 196 GL +LL Sbjct: 180 FGLRNLL 186 >gi|223029430 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 2 [Homo sapiens] Length = 445 Score = 155 bits (391), Expect = 1e-37 Identities = 135/462 (29%), Positives = 210/462 (45%), Gaps = 69/462 (14%) Query: 26 LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSV 85 LA F+AVLG+ FGY + + +E+S + P LT A Sbjct: 40 LATFAAVLGNFSFGYALVYTSPVIPALERSLD---------------PDLHLTKSQASWF 84 Query: 86 -AIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFL 144 ++F++G I++ LGRK +++ + V + G +LM A ML+LGR L Sbjct: 85 GSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTL 141 Query: 145 IGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPL 204 G GLT+ +P+YV EIAP +RGALG QL V G L LGL LL W Sbjct: 142 TGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LLP----WRW 195 Query: 205 LLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGW-ADVSGVLAELKDE 263 L P L+ ++LL F P SPR+L + + + A ++L L G DV +++D Sbjct: 196 LAVAGEAPVLIMILLLSFMPNSPRFL-LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN 254 Query: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPA 323 R+ + +S + R P+ +A++++L QQL+GI + Y SIF++ V P Sbjct: 255 VRR--QSSRVSWAEARAPHVCR-PITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPP 311 Query: 324 YATIG-AGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSY 382 G V + L++ L ++ AGR+ L Sbjct: 312 KDDAAIVGAVRLLSVLIAALTMDLAGRKVLL----------------------------- 342 Query: 383 VSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVA 442 FV+ + +G GPI W +++E+ R A + ++W + F++ F V Sbjct: 343 --------FVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVV 394 Query: 443 EAMGPYV-FLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483 G V F FA + L +FT VPET+GR+ +QI + F Sbjct: 395 STFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436 >gi|203098995 solute carrier family 2 (facilitated glucose transporter), member 13 [Homo sapiens] Length = 648 Score = 152 bits (384), Expect = 7e-37 Identities = 123/384 (32%), Positives = 194/384 (50%), Gaps = 46/384 (11%) Query: 25 VLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALS 84 V+AVFSA LG FGY+ GV++ ++++ + L LW Sbjct: 83 VVAVFSA-LGGFLFGYDTGVVSGAMLLLKRQLS-------------------LDALWQEL 122 Query: 85 VAIFSVGGM-ISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143 + +VG +S+ G ++ GR+ A+L+ + L G +++ AN + E L+ GR Sbjct: 123 LVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN---NKETLLAGRL 179 Query: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVL-GLESLLGTASLW 202 ++G G+ S VP+Y+ E++P +LRG L T+N L I G A V+ G S L W Sbjct: 180 VVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-W 238 Query: 203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADV----SGVLA 258 +LGL +PA++Q F PESPR+L I + AR+ L ++ G + + Sbjct: 239 RYMLGLAAVPAVIQFFGFLFLPESPRWL-IQKGQTQKARRILSQMRGNQTIDEEYDSIKN 297 Query: 259 ELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAG 318 +++E++++ P+ + ++L R+ LI+ LQ+ QQLSGIN + YYS +I + +G Sbjct: 298 NIEEEEKEVGSAGPV-ICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSG 356 Query: 319 VGQPAYATIGAGV---VNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLE 375 V A A V N +FTLV V LVE+ GRR L LAG TVAL++L Sbjct: 357 VEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAG-------TTVALIIL- 408 Query: 376 RVPAMSYVSIVAIFGFVAFFEIGP 399 A+ +V + + F I P Sbjct: 409 ---ALGFVLSAQVSPRITFKPIAP 429 Score = 58.2 bits (139), Expect = 2e-08 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Query: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 S+ +++ + ++ FF G GP+PW + +E++ R A + NW N ++ + F + Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565 Query: 441 VAEAMGPY-VFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483 AE + Y F L+A +F + +PET+G+ ++I + F Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLF 609 >gi|21553331 solute carrier family 2 (facilitated glucose transporter), member 12 [Homo sapiens] Length = 617 Score = 130 bits (328), Expect = 2e-30 Identities = 108/376 (28%), Positives = 178/376 (47%), Gaps = 45/376 (11%) Query: 9 GSEDGEPPQQRVTGTLV-LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPE 67 GS PP R G L+ +A + L GY +G+I+ I+ Sbjct: 24 GSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIK-------------- 69 Query: 68 GPSSIPPGTLTTLWALS-------VAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV 120 TL ALS V+ +G +++S G++ GR+ A+++++ L Sbjct: 70 -----------TLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLG 118 Query: 121 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI 180 LG ++ L+ SY +LI+GR IG L+S +Y+ EIAP H RG L +LN+L I Sbjct: 119 LGSLVLILS---LSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMI 175 Query: 181 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA 240 VIGIL A + + W + GL + +LQ + + F P SPR+L +++ EG A Sbjct: 176 VIGILSAYISNY-AFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFL-VMKGQEGAA 233 Query: 241 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTH-RQPLIIAVVLQLSQQ 299 K L RL +D + EL K L+ E S L S+ + R ++I + L Q Sbjct: 234 SKVLGRLRALSDTT---EELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQ 290 Query: 300 LSGINAVFYYSTSIFETAGVGQ---PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLG 356 ++G + +Y++++ ++ G + A+ G GVV + T+ + LLV+ G +T +G Sbjct: 291 ITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIG 350 Query: 357 LAGMCGCAILMTVALL 372 + M + M + L Sbjct: 351 SSVMAASLVTMGIVNL 366 Score = 79.3 bits (194), Expect = 7e-15 Identities = 38/106 (35%), Positives = 66/106 (62%), Gaps = 2/106 (1%) Query: 377 VPA-MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIG 435 VPA + ++S+ ++ +VA F IG GP+PW +++E+F G R AMA+ NW N +I Sbjct: 456 VPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLIS 515 Query: 436 MGFQYVAEAMG-PYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS 480 + F V + +G P+V ++ ++ L +F + +PET+G + +QIS Sbjct: 516 LTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561 >gi|13540547 solute carrier family 2 member 10 [Homo sapiens] Length = 541 Score = 108 bits (271), Expect = 9e-24 Identities = 101/342 (29%), Positives = 154/342 (45%), Gaps = 47/342 (13%) Query: 24 LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83 L L ++LG L FGY + VI+ ++ + + L ++ Sbjct: 8 LPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQE------------------F 49 Query: 84 SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143 V +G +++S + G + GRK+A+L +N++ + G +GLA + A L+LGR Sbjct: 50 LVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLA---WLVLGRA 106 Query: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203 ++G L+S +YV E+ RG L +L + I +GIL++ L +L GT W Sbjct: 107 VVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNY-ALAGTPWGWR 165 Query: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263 + G PA+LQ + L F P E K L L G E Sbjct: 166 HMFGWATAPAVLQSLSLLFLPAGTD--------ETATHKDLIPLQG------------GE 205 Query: 264 KRKLERERP-LSLLQLLGSRTH-RQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV-- 319 KL RP S L L +R + R + + L L QQL+G V Y+++IF + G Sbjct: 206 APKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265 Query: 320 -GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM 360 A++G G V TL ++ LV+RAGRR L L G A M Sbjct: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALM 307 Score = 60.1 bits (144), Expect = 5e-09 Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 7/110 (6%) Query: 380 MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQ 439 + + +++ + FV+ F G GP+ W +++E++ R A A NW +N I + F Sbjct: 408 LRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFL 467 Query: 440 YVAEAMG-PYVFLLF---AVLLLGFFIFTFLRVPETRGRTFDQISAAFHR 485 + +G + FLL+ AVL LGF +L VPET+G++ +I F + Sbjct: 468 DLIGTIGLSWTFLLYGLTAVLGLGFI---YLFVPETKGQSLAEIDQQFQK 514 >gi|170650643 solute carrier family 22, member 23 isoform a [Homo sapiens] Length = 686 Score = 60.1 bits (144), Expect = 5e-09 Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 19/225 (8%) Query: 81 WALSVAIFSV-GGMISSFLI-GIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEML 138 W + +A FS+ G+I +LI G I+ W+GR+ +L + + ++ G + L+ + L Sbjct: 227 WKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTL 286 Query: 139 ILGRFLIG-AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG 197 RF G +G+ L + + E+ P R + + + G + + L Sbjct: 287 ---RFFEGFCLAGIILTLYALRI-ELCPPGKRFMITMVASFVAMAGQFL-----MPGLAA 337 Query: 198 TASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSL-----KRLTGWAD 252 W +L L + P LL L+ PES R+L Q E R L R+ D Sbjct: 338 LCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGD 397 Query: 253 VSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLS 297 + GV+ EL EK R + + +++++G+R + +++ V L+ Sbjct: 398 IKGVIPEL--EKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLT 440 >gi|24497497 solute carrier family 22 member 7 isoform a [Homo sapiens] Length = 546 Score = 57.0 bits (136), Expect = 4e-08 Identities = 115/471 (24%), Positives = 190/471 (40%), Gaps = 73/471 (15%) Query: 64 QGPEGPSSIPPGTLTTLWAL----------SVAIFSVGGMISSFLIGIISQWLGRKRAML 113 QG E S T+ T W L + F G ++ + G +S GR+R +L Sbjct: 115 QGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLL 174 Query: 114 VNNVLAVLGGSLMGLANAAA-SYEMLILGRFLIG-AYSGLTSGLVPMYVGEIAPTHLRGA 171 V A + ++GLA+AA+ SY M + R L G A +G T ++P+ + + H R Sbjct: 175 V----AYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEH-RTV 229 Query: 172 LGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLY 231 G L+ G+++ ++G W LL LP ++ L + PES R+L Sbjct: 230 AGVLSSTFWTGGVMLLALVGY-----LIRDWRWLLLAVTLPCAPGILSLWWVPESARWLL 284 Query: 232 IIQNLEGPARKSLKRLTGWADVSG-----------VLAELKDEKRKLERERPLSLLQLLG 280 +G +++ + L A ++G ++++ +R + R S L L Sbjct: 285 ----TQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRP---SYLDLFR 337 Query: 281 SRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYAT-IGAGVVNTVFTLV 339 + R + VV+ S YY S+ + +G+G Y T + G V L+ Sbjct: 338 TPRLRHISLCCVVVWFGVNFS------YYGLSL-DVSGLGLNVYQTQLLFGAVELPSKLL 390 Query: 340 SVLLVERAGRRTLH---LLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFE 396 L V AGRR LLG A G +L++ + S+ +++A+ G AF E Sbjct: 391 VYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDM--------KSWSTVLAVMG-KAFSE 441 Query: 397 IGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVL 456 F A LF+ P + G +G +A A+ V+L L Sbjct: 442 AA------FTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLA-ALLDGVWLSLPKL 494 Query: 457 LLGFFIF----TFLRVPETRGRTFDQISAAFHR--TPSLLEQEVKPSTELE 501 G T L +PETR + R P+ L++E P +++ Sbjct: 495 TYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEMPMKQVQ 545 >gi|24497499 solute carrier family 22 member 8 [Homo sapiens] Length = 542 Score = 56.2 bits (134), Expect = 7e-08 Identities = 77/314 (24%), Positives = 128/314 (40%), Gaps = 25/314 (7%) Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142 ++ +IF G +I ++G +S GR+ + + +L GS A + ++ + ++ R Sbjct: 124 MAQSIFMAGILIGGLVLGDLSDRFGRRPILTCSYLLLAASGS---GAAFSPTFPIYMVFR 180 Query: 143 FLIG-AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASL 201 FL G SG+T V + V E PT +R + T G I L L Sbjct: 181 FLCGFGISGITLSTVILNV-EWVPTRMRAIMSTALGYCYTFGQFI-----LPGLAYAIPQ 234 Query: 202 WPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAE-- 259 W L +P + + + PES R+L L G + K+LK L A +G E Sbjct: 235 WRWLQLTVSIPFFVFFLSSWWTPESIRWLV----LSGKSSKALKILRRVAVFNGKKEEGE 290 Query: 260 ---LKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFET 316 L++ K L++E L+ + S R P++ + LS +Y E Sbjct: 291 RLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFATGFAYYSLAMGVEE 350 Query: 317 AGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLER 376 GV I G V+ +++L + GR T L G + +T L L+ Sbjct: 351 FGVNLYILQIIFGG-VDVPAKFITILSLSYLGRHTTQAAALLLAGGAILALTFVPLDLQT 409 Query: 377 VPAMSYVSIVAIFG 390 V +++A+FG Sbjct: 410 VR-----TVLAVFG 418 >gi|90669191 solute carrier family 22 member 7 isoform b [Homo sapiens] Length = 548 Score = 55.8 bits (133), Expect = 9e-08 Identities = 107/437 (24%), Positives = 180/437 (41%), Gaps = 63/437 (14%) Query: 88 FSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAA-SYEMLILGRFLIG 146 F G ++ + G +S GR+R +LV A + ++GLA+AA+ SY M + R L G Sbjct: 151 FFAGVLVGAVAFGYLSDRFGRRRLLLV----AYVSTLVLGLASAASVSYVMFAITRTLTG 206 Query: 147 -AYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLL 205 A +G T ++P+ + + H R G L+ G+++ ++G W L Sbjct: 207 SALAGFTIIVMPLELEWLDVEH-RTVAGVLSSTFWTGGVMLLALVGY-----LIRDWRWL 260 Query: 206 LGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSG---------- 255 L LP ++ L + PES R+L +G +++ + L A ++G Sbjct: 261 LLAVTLPCAPGILSLWWVPESARWLL----TQGHVKEAHRYLLHCARLNGRPVCEDSFSQ 316 Query: 256 -VLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIF 314 ++++ +R + R S L L + R + VV+ S YY S+ Sbjct: 317 EAVSKVAAGERVVRRP---SYLDLFRTPRLRHISLCCVVVWFGVNFS------YYGLSL- 366 Query: 315 ETAGVGQPAYAT-IGAGVVNTVFTLVSVLLVERAGRRTLH---LLGLAGMCGCAILMTVA 370 + +G+G Y T + G V L+ L V AGRR LLG A G +L++ Sbjct: 367 DVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSD 426 Query: 371 LLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTS 430 + S+ +++A+ G AF E F A LF+ P + G Sbjct: 427 M--------KSWSTVLAVMG-KAFSEAA------FTTAYLFTSELYPTVLRQTGMGLTAL 471 Query: 431 NFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIF----TFLRVPETRGRTFDQISAAFHR- 485 +G +A A+ V+L L G T L +PETR + R Sbjct: 472 VGRLGGSLAPLA-ALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERK 530 Query: 486 -TPSLLEQEVKPSTELE 501 P+ L++E P +++ Sbjct: 531 SAPTSLQEEEMPMKQVQ 547 >gi|213021148 SVOP-like isoform 1 [Homo sapiens] Length = 492 Score = 54.7 bits (130), Expect = 2e-07 Identities = 42/149 (28%), Positives = 74/149 (49%), Gaps = 8/149 (5%) Query: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141 AL + G M+ S L G+++ GR + +L++ + G L + A SY + Sbjct: 87 ALVTTMVFFGYMVFSILFGLLADRYGRWKILLIS---FLWGAYFSLLTSFAPSYIWFVFL 143 Query: 142 RFLIGA-YSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTAS 200 R ++G SG + GL+ E PT RG + L+Q+ + G L+ ++GL S++ Sbjct: 144 RTMVGCGVSGHSQGLI--IKTEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199 Query: 201 LWPLLLGLTVLPALLQLVLLPFCPESPRY 229 W L+ + +P ++ +V F PES R+ Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARF 228 Score = 34.7 bits (78), Expect = 0.21 Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 9/109 (8%) Query: 98 LIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVP 157 ++GI +LGR+ ++ + L L+ + ++A LI F++ A V Sbjct: 362 ILGI--NFLGRRLSLSITMGCTALFFLLLNICTSSAG---LIGFLFMLRALVAANFNTVY 416 Query: 158 MYVGEIAPTHLR----GALGTLNQLAIVIGILIAQVLGLESLLGTASLW 202 +Y E+ PT +R G G+L ++ ++ I+QVL S+LG L+ Sbjct: 417 IYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSASILGALCLF 465 >gi|4507005 solute carrier family 22 member 5 [Homo sapiens] Length = 557 Score = 51.2 bits (121), Expect = 2e-06 Identities = 108/429 (25%), Positives = 187/429 (43%), Gaps = 58/429 (13%) Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMG---LANAAASYEMLI 139 L++++F VG ++ SF+ G +S GRK NVL V G G L + ++EM + Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRK------NVLFVTMGMQTGFSFLQIFSKNFEMFV 197 Query: 140 LGRFLIGAYSGLTSGLVPMYV--GEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG 197 + L+G G S V +V EI +R TL G+ I G L Sbjct: 198 VLFVLVG--MGQISNYVAAFVLGTEILGKSVRIIFSTL-------GVCIFYAFGYMVLPL 248 Query: 198 TASL---WPLLLGLTVLPALLQLVLLPFCPESPRYLYI---IQNLEGPARKSLKRLTGWA 251 A W +LL +P +L + L F PESPR+L + E RK+ K G Sbjct: 249 FAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAK-ANGIV 307 Query: 252 DVSGVL--AELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYY 309 S + +EL+D K +++ ++L LL + R I++++L ++ +V Y+ Sbjct: 308 VPSTIFDPSELQDLSSK--KQQSHNILDLLRTWNIRMVTIMSIMLWMT------ISVGYF 359 Query: 310 STSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTV 369 S+ G + +V +++ LL++ RR + + A G ++L+ + Sbjct: 360 GLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRR--YSMATALFLGGSVLLFM 417 Query: 370 ALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWT 429 L+ + + + +V FG A F + + AEL+ R + V+ ++ Sbjct: 418 QLVPPDLYYLATVLVMVGKFGVTAAFS-----MVYVYTAELYPTVVRNMGVGVSSTASRL 472 Query: 430 SNFIIGMGFQYVA--EAMGPYVFLLFAVLLLGFFIFTFLRVPETRGR----TFDQ---IS 480 + I+ F Y+ + PY+ L+ ++ +L + FL PE+ G T DQ + Sbjct: 473 GS-ILSPYFVYLGAYDRFLPYI-LMGSLTILTAILTLFL--PESFGTPLPDTIDQMLRVK 528 Query: 481 AAFHR-TPS 488 HR TPS Sbjct: 529 GMKHRKTPS 537 >gi|24497490 solute carrier family 22 member 4 [Homo sapiens] Length = 551 Score = 49.7 bits (117), Expect = 6e-06 Identities = 88/402 (21%), Positives = 172/402 (42%), Gaps = 34/402 (8%) Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142 L+ ++F VG ++ SF+ G +S GRK + +AV G L + S+EM + Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFAT--MAVQTGFSF-LQIFSISWEMFTV-L 199 Query: 143 FLIGAYSGLTSGLVPMYVG-EIAPTHLRGALGTLNQLAI-VIGILIAQVLGLESLLGTAS 200 F+I +++ +V +G EI +R TL +G ++ + Sbjct: 200 FVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAY-----FIR 254 Query: 201 LWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVS--GVLA 258 W +LL +P +L + L F PESPR+L I Q A +++ +++ V+ Sbjct: 255 DWRMLLLALTVPGVLCVPLWWFIPESPRWL-ISQRRFREAEDIIQKAAKMNNIAVPAVIF 313 Query: 259 ELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAG 318 + +E L++++ +L L +R IA++ +S L + +V Y++ S+ Sbjct: 314 DSVEELNPLKQQKAF-ILDLFRTRN------IAIMTIMSLLLWMLTSVGYFALSLDAPNL 366 Query: 319 VGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVP 378 G + ++ + + LL+ RR +++ G +L+ + L+ ++ Sbjct: 367 HGDAYLNCFLSALIEIPAYITAWLLLRTLPRR--YIIAAVLFWGGGVLLFIQLVPVDYYF 424 Query: 379 AMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGF 438 + ++ FG + F + + AEL+ R A+ V ++ + II F Sbjct: 425 LSIGLVMLGKFGITSAFS-----MLYVFTAELYPTLVRNMAVGVTSTASRVGS-IIAPYF 478 Query: 439 QYVA--EAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQ 478 Y+ M PY+ + +L+G F PE+ G T + Sbjct: 479 VYLGAYNRMLPYIVMGSLTVLIGILTLFF---PESLGMTLPE 517 >gi|166197673 solute carrier family 22, member 15 [Homo sapiens] Length = 547 Score = 49.3 bits (116), Expect = 8e-06 Identities = 42/147 (28%), Positives = 62/147 (42%), Gaps = 10/147 (6%) Query: 86 AIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANA-AASYEMLILGRFL 144 + F G + G +S GRK+ L L +L +AN + SYE + RFL Sbjct: 116 SFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDIL----FAIANGFSPSYEFFAVTRFL 171 Query: 145 IGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPL 204 +G +G S + + + E T G++ L +GI +LG W Sbjct: 172 VGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGY-----FIRSWRT 226 Query: 205 LLGLTVLPALLQLVLLPFCPESPRYLY 231 L L L + +L F PESPR+LY Sbjct: 227 LAILVNLQGTVVFLLSLFIPESPRWLY 253 >gi|11415038 solute carrier family 22 member 3 [Homo sapiens] Length = 556 Score = 49.3 bits (116), Expect = 8e-06 Identities = 74/296 (25%), Positives = 128/296 (43%), Gaps = 31/296 (10%) Query: 83 LSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANA-AASYEMLILG 141 L+ AI ++G + +F +G + GR +V +L+ LG + G+ A A ++ + ++ Sbjct: 156 LTQAILNLGFLTGAFTLGYAADRYGR----IVIYLLSCLGVGVTGVVVAFAPNFPVFVIF 211 Query: 142 RFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASL 201 RFL G + T + V EI + R +G + Q+ +GI+I L G A Sbjct: 212 RFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIII--------LPGIAYF 263 Query: 202 WPLLLGLTV---LPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLT--GWADVSGV 256 P G+ + LP+ L L+ PESPR+L I + A + L+R+ +S Sbjct: 264 IPNWQGIQLAITLPSFLFLLYYWVVPESPRWL-ITRKKGDKALQILRRIAKCNGKYLSSN 322 Query: 257 LAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFET 316 +E+ ++ S L L+ + R+ +I + + + Y + Sbjct: 323 YSEITVTDEEVSNP---SFLDLVRTPQMRKCTLILM-------FAWFTSAVVYQGLVMRL 372 Query: 317 AGVGQPAYATIG-AGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVAL 371 +G Y +GVV L+ +L +ER GRR L + G A L+T L Sbjct: 373 GIIGGNLYIDFFISGVVELPGALLILLTIERLGRR-LPFAASNIVAGVACLVTAFL 427 >gi|4507001 solute carrier family 22 member 2 [Homo sapiens] Length = 555 Score = 48.9 bits (115), Expect = 1e-05 Identities = 47/182 (25%), Positives = 77/182 (42%), Gaps = 12/182 (6%) Query: 89 SVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAY 148 +VG I S IG I+ GRK +L ++ G LM + + +Y +++ R + G Sbjct: 157 NVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAI---SPTYTWMLIFRLIQGLV 213 Query: 149 SGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGL 208 S + + + E R +G Q+A +G+L+ L + W L Sbjct: 214 SKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLLV-----LAGVAYALPHWRWLQFT 268 Query: 209 TVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLE 268 LP L+ PESPR+L I QN A + +K + A +G ++ +LE Sbjct: 269 VALPNFFFLLYYWCIPESPRWL-ISQNKNAEAMRIIKHI---AKKNGKSLPASLQRLRLE 324 Query: 269 RE 270 E Sbjct: 325 EE 326 >gi|24308167 SV2 related protein [Homo sapiens] Length = 548 Score = 48.9 bits (115), Expect = 1e-05 Identities = 52/166 (31%), Positives = 75/166 (45%), Gaps = 7/166 (4%) Query: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141 AL ++ VG M SS L G IS GRK + ++ + + G L A Y +++ Sbjct: 123 ALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPV---YSWILVL 179 Query: 142 RFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASL 201 R L+G G V +Y E P R L ++ IG + VL + + Sbjct: 180 RGLVGFGIGGVPQSVTLYA-EFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLG-- 236 Query: 202 WPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRL 247 W LL L+ +P LL VL + PES RY + N E A +LKR+ Sbjct: 237 WRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQE-KAIATLKRI 281 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,746,681 Number of Sequences: 37866 Number of extensions: 811207 Number of successful extensions: 2185 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 2082 Number of HSP's gapped (non-prelim): 69 length of query: 509 length of database: 18,247,518 effective HSP length: 107 effective length of query: 402 effective length of database: 14,195,856 effective search space: 5706734112 effective search space used: 5706734112 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.