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Search of human proteins with 4507009
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507009 solute carrier family 25, member 14 isoform UCP5L
[Homo sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 648 0.0
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 637 0.0
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 478 e-135
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 214 1e-55
gi|13259541 uncoupling protein 2 [Homo sapiens] 199 2e-51
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 196 2e-50
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 189 2e-48
gi|11225256 uncoupling protein 1 [Homo sapiens] 172 5e-43
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 158 5e-39
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic... 134 1e-31
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 115 5e-26
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 107 2e-23
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 106 3e-23
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 106 3e-23
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 106 3e-23
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 106 3e-23
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 106 3e-23
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 106 3e-23
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 106 3e-23
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 106 3e-23
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 104 9e-23
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 104 9e-23
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 104 9e-23
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 101 8e-22
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 100 2e-21
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 99 4e-21
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 99 7e-21
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 99 7e-21
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 96 3e-20
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 96 3e-20
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 648 bits (1672), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP
Sbjct: 1 MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
Query: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI
Sbjct: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
Query: 121 KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM 180
KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM
Sbjct: 121 KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM 180
Query: 181 IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV 240
IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV
Sbjct: 181 IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV 240
Query: 241 SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW 300
SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW
Sbjct: 241 SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW 300
Query: 301 PNWLRLGPWNIIFFITYEQLKRLQI 325
PNWLRLGPWNIIFFITYEQLKRLQI
Sbjct: 301 PNWLRLGPWNIIFFITYEQLKRLQI 325
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 637 bits (1644), Expect = 0.0
Identities = 322/325 (99%), Positives = 322/325 (99%), Gaps = 3/325 (0%)
Query: 1 MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
MGIFPGIILIFLRVKFATAAVI HQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP
Sbjct: 1 MGIFPGIILIFLRVKFATAAVI---HQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 57
Query: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI
Sbjct: 58 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 117
Query: 121 KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM 180
KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM
Sbjct: 118 KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSM 177
Query: 181 IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV 240
IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV
Sbjct: 178 IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFV 237
Query: 241 SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW 300
SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW
Sbjct: 238 SSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW 297
Query: 301 PNWLRLGPWNIIFFITYEQLKRLQI 325
PNWLRLGPWNIIFFITYEQLKRLQI
Sbjct: 298 PNWLRLGPWNIIFFITYEQLKRLQI 322
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 478 bits (1231), Expect = e-135
Identities = 234/291 (80%), Positives = 262/291 (90%), Gaps = 1/291 (0%)
Query: 36 MSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRIC 95
MS LNWKPFVYGGLASI AE GTFP+DLTKTRLQ+QGQ+ DA+FKEI+YRGM HAL RI
Sbjct: 1 MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIG 60
Query: 96 KEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVIS 155
+EEG+ ALYSGIAPA+LRQASYGTIKIG YQSLKRLF+ER EDETL IN+ICG++SGVIS
Sbjct: 61 REEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVIS 120
Query: 156 STIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVEL 215
STIANPTDVLKIRMQAQ + QG MIG+F++IYQQEGTRGLW+GV TAQRAAIVVGVEL
Sbjct: 121 STIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVEL 180
Query: 216 PVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAI-VGHVD 274
PVYDITKKHLILSG+MGDT+ THF+SSFTCGLAGALASNPVDVVRTRMMNQR + G
Sbjct: 181 PVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCS 240
Query: 275 LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325
Y GT+D +L+ WK+EGFFALYKGFWPNWLRLGPWNIIFF+TYEQLK+L +
Sbjct: 241 GYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 214 bits (544), Expect = 1e-55
Identities = 118/296 (39%), Positives = 181/296 (61%), Gaps = 17/296 (5%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARF-----KEIKYRGMFHALFRICKEE 98
F+ G A+ VAE TFP+DLTKTRLQ+QG++ AR + YRGM I +EE
Sbjct: 23 FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82
Query: 99 GVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDE--TLLINMICGVVSGVISS 156
G L L+ G+ PA+ R Y ++ Y+ L+ + + EDE L ++I G+++GVI
Sbjct: 83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVIGQ 142
Query: 157 TIANPTDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
+ANPTD++K++MQ +G F+G + +F I + G RGLW G VP QRAA
Sbjct: 143 FLANPTDLVKVQMQMEGKRKLEGKPLRFRG-VHHAFAKILAEGGIRGLWAGWVPNIQRAA 201
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ-R 267
+V +L YD K +L+L+ + D I+TH +SS GL ++ P DV+++R+MNQ R
Sbjct: 202 LVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQPR 261
Query: 268 AIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
G LYK + D +++ + EGF +LYKGF P+WLR+ PW+++F++TYE+++ +
Sbjct: 262 DKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREM 317
Score = 77.4 bits (189), Expect = 2e-14
Identities = 46/171 (26%), Positives = 88/171 (51%), Gaps = 10/171 (5%)
Query: 41 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 100
WK + G +A ++ +F P DL K ++Q++G+ K +++RG+ HA +I E G+
Sbjct: 128 WKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKR-KLEGKPLRFRGVHHAFAKILAEGGI 186
Query: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLE-DETLLINMICGVVSGVISSTIA 159
L++G P + R A + Y ++K V ++ ++ + + + SG+++S +
Sbjct: 187 RGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILG 246
Query: 160 NPTDVLKIRM-------QAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPT 203
P DV+K R+ Q +G L++ S I Q EG L++G +P+
Sbjct: 247 TPADVIKSRIMNQPRDKQGRGLLYKSS-TDCLIQAVQGEGFMSLYKGFLPS 296
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 199 bits (507), Expect = 2e-51
Identities = 107/285 (37%), Positives = 164/285 (57%), Gaps = 11/285 (3%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDA--RFKEIKYRGMFHALFRICKEEGVL 101
F+ G A+ +A+ TFP+D K RLQ+QG+S +YRG+ + + + EG
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPR 76
Query: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANP 161
+LY+G+ L RQ S+ +++IG+Y S+K+ + + E ++ ++ G +G ++ +A P
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQP 136
Query: 162 TDVLKIRMQAQGSLFQG----SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPV 217
TDV+K+R QAQ G S + ++ I ++EG RGLW+G P R AIV EL
Sbjct: 137 TDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVT 196
Query: 218 YDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYK 277
YD+ K L+ + +M D + HF S+F G + ++PVDVV+TR MN + Y
Sbjct: 197 YDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSA-----LGQYS 251
Query: 278 GTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
L M + EG A YKGF P++LRLG WN++ F+TYEQLKR
Sbjct: 252 SAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
Score = 69.7 bits (169), Expect = 3e-12
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 12/192 (6%)
Query: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQG----------SLFQGSMIGSFIDIYQ 189
T + + + I+ I P D K+R+Q QG S ++G+ + + +
Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVR 71
Query: 190 QEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAG 249
EG R L+ G+V QR V + +YD + K G +I + ++ T G
Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYD-SVKQFYTKGSEHASIGSRLLAGSTTGALA 130
Query: 250 ALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPW 309
+ P DVV+ R Q A G Y+ TV+ + + EGF L+KG PN R
Sbjct: 131 VAVAQPTDVVKVRFQAQ-ARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIV 189
Query: 310 NIIFFITYEQLK 321
N +TY+ +K
Sbjct: 190 NCAELVTYDLIK 201
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 196 bits (499), Expect = 2e-50
Identities = 108/289 (37%), Positives = 170/289 (58%), Gaps = 16/289 (5%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKE-IKYRGMFHALFRICKEEGVLA 102
F+ G A+ A+ TFP+D K RLQ+QG++ + ++YRG+ + + + EG +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 103 LYSGIAPALLRQASYGTIKIGIYQSLKRLFVER-LEDETLLINMICGVVSGVISSTIANP 161
Y+G+ L RQ S+ +I+IG+Y S+K+++ + ++ +L ++ G +G ++ T A P
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Query: 162 TDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGV 213
TDV+K+R QA L + G+M ++ I ++EG RGLW+G +P R AIV
Sbjct: 137 TDVVKVRFQASIHLGPSRSDRKYSGTM-DAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
Query: 214 ELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHV 273
E+ YDI K+ L+ ++ D HFVS+F G + ++PVDVV+TR MN
Sbjct: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP----- 250
Query: 274 DLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Y +D ++KM EG A YKGF P++LRLG WN++ F+TYEQLKR
Sbjct: 251 GQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Score = 63.2 bits (152), Expect = 3e-10
Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS---------LFQGSMIGSFIDIYQQ 190
T+ + + + + + P D K+R+Q QG + ++G+ + + +
Sbjct: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
Query: 191 EGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGA 250
EG + G+V QR + + +YD K+ G ++ T ++ T G
Sbjct: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
Query: 251 LASNPVDVVRTRMMNQRAIVGHVD------LYKGTVDGILKMWKHEGFFALYKGFWPNWL 304
+ P DVV+ R Q +I H+ Y GT+D + + EG L+KG PN +
Sbjct: 132 TCAQPTDVVKVRF--QASI--HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIM 187
Query: 305 RLGPWNIIFFITYEQLK 321
R N +TY+ LK
Sbjct: 188 RNAIVNCAEVVTYDILK 204
Score = 37.7 bits (86), Expect = 0.014
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F G A++VA PVD+ KTR +Y + ++ +EG A
Sbjct: 225 FGAGFCATVVAS----PVDVVKTRYMNSPPG--------QYFSPLDCMIKMVAQEGPTAF 272
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVE 134
Y G P+ LR S+ + Y+ LKR ++
Sbjct: 273 YKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 189 bits (481), Expect = 2e-48
Identities = 114/309 (36%), Positives = 168/309 (54%), Gaps = 20/309 (6%)
Query: 29 STTVSHEMSGLNWKP--------FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFK 80
+ T S G++ KP F++GGLA + A P+DL K R+Q+ G+ R
Sbjct: 2 AATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTR-- 59
Query: 81 EIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSL-KRLFVERLEDE 139
+Y+ FHAL I K EG+ +Y+G++ LLRQA+Y T ++GIY L +RL
Sbjct: 60 --EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPP 117
Query: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIG------SFIDIYQQEGT 193
L+ + G+ +G + + P +V IRM A G L G + I I ++EG
Sbjct: 118 GFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGV 177
Query: 194 RGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALAS 253
LWRG +PT RA +V +L Y +K+ L+ SG D IL HF +S GL AS
Sbjct: 178 LTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAAS 237
Query: 254 NPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIF 313
PVD+ +TR+ N R I G + YK +D + K+ ++EGFF+L+KGF P + RLGP ++
Sbjct: 238 MPVDIAKTRIQNMRMIDGKPE-YKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLT 296
Query: 314 FITYEQLKR 322
FI EQ+ +
Sbjct: 297 FIFLEQMNK 305
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 172 bits (435), Expect = 5e-43
Identities = 97/282 (34%), Positives = 157/282 (55%), Gaps = 15/282 (5%)
Query: 48 GLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGI 107
G+A+ +A+ TFP+D K RLQVQG+ + I+Y+G+ + + K EG + LYSG+
Sbjct: 21 GIAACLADVITFPLDTAKVRLQVQGECPTSSV--IRYKGVLGTITAVVKTEGRMKLYSGL 78
Query: 108 APALLRQASYGTIKIGIYQSLKRLFVERLEDETLL-INMICGVVSGVISSTIANPTDVLK 166
L RQ S +++IG+Y +++ E L ++ G+ +G ++ I PT+V+K
Sbjct: 79 PAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVK 138
Query: 167 IRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
+R+QAQ L + G+ ++ I EG GLW+G P R+ I+ EL YD+
Sbjct: 139 VRLQAQSHLHGIKPRYTGTY-NAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDL 197
Query: 221 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTV 280
K+ + + ++ D + H VS+ G S+PVDVV+TR +N YK
Sbjct: 198 MKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPP-----GQYKSVP 252
Query: 281 DGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
+ +K++ +EG A +KG P++LRLG WN+I F+ +EQLKR
Sbjct: 253 NCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKR 294
Score = 67.0 bits (162), Expect = 2e-11
Identities = 45/188 (23%), Positives = 80/188 (42%), Gaps = 6/188 (3%)
Query: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMI------GSFIDIYQQEGT 193
TL + + ++ ++ I P D K+R+Q QG S+I G+ + + EG
Sbjct: 12 TLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGR 71
Query: 194 RGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALAS 253
L+ G+ QR + + +YD ++ L ++ + ++ T G
Sbjct: 72 MKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIG 131
Query: 254 NPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIF 313
P +VV+ R+ Q + G Y GT + + EG L+KG PN +R N
Sbjct: 132 QPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTE 191
Query: 314 FITYEQLK 321
+TY+ +K
Sbjct: 192 LVTYDLMK 199
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 158 bits (400), Expect = 5e-39
Identities = 92/265 (34%), Positives = 149/265 (56%), Gaps = 16/265 (6%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKE-IKYRGMFHALFRICKEEGVLA 102
F+ G A+ A+ TFP+D K RLQ+QG++ + ++YRG+ + + + EG +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 103 LYSGIAPALLRQASYGTIKIGIYQSLKRLFVER-LEDETLLINMICGVVSGVISSTIANP 161
Y+G+ L RQ S+ +I+IG+Y S+K+++ + ++ +L ++ G +G ++ T A P
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Query: 162 TDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGV 213
TDV+K+R QA L + G+M ++ I ++EG RGLW+G +P R AIV
Sbjct: 137 TDVVKVRFQASIHLGPSRSDRKYSGTM-DAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
Query: 214 ELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHV 273
E+ YDI K+ L+ ++ D HFVS+F G + ++PVDVV+TR MN
Sbjct: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP----- 250
Query: 274 DLYKGTVDGILKMWKHEGFFALYKG 298
Y +D ++KM EG A YKG
Sbjct: 251 GQYFSPLDCMIKMVAQEGPTAFYKG 275
Score = 63.2 bits (152), Expect = 3e-10
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 21/198 (10%)
Query: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS----------LFQGSMIGSFIDIYQ 189
T+ + + + + + P D K+R+Q QG ++G ++G+ + + +
Sbjct: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG-VLGTILTMVR 70
Query: 190 QEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAG 249
EG + G+V QR + + +YD K+ G ++ T ++ T G
Sbjct: 71 TEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMA 130
Query: 250 ALASNPVDVVRTRMMNQRAIVGHVD------LYKGTVDGILKMWKHEGFFALYKGFWPNW 303
+ P DVV+ R Q +I H+ Y GT+D + + EG L+KG PN
Sbjct: 131 VTCAQPTDVVKVRF--QASI--HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186
Query: 304 LRLGPWNIIFFITYEQLK 321
+R N +TY+ LK
Sbjct: 187 MRNAIVNCAEVVTYDILK 204
>gi|20149598 solute carrier family 25 (mitochondrial carrier;
dicarboxylate transporter), member 10 [Homo sapiens]
Length = 287
Score = 134 bits (337), Expect = 1e-31
Identities = 90/284 (31%), Positives = 144/284 (50%), Gaps = 23/284 (8%)
Query: 46 YGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYS 105
+GGLAS A T P+DL K LQ Q +E+K R AL R+ + +G+LALYS
Sbjct: 12 FGGLASCGAACCTHPLDLLKVHLQTQ--------QEVKLRMTGMAL-RVVRTDGILALYS 62
Query: 106 GIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN-MICGVVSGVISSTIANPTDV 164
G++ +L RQ +Y + IY++++ + + ++ G VSG+ + P D+
Sbjct: 63 GLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADL 122
Query: 165 LKIRMQAQGSLFQGSM------IGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVY 218
+ +RMQ L QG + + ++EG R L+ G + R A+V +L Y
Sbjct: 123 VNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCY 182
Query: 219 DITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKG 278
D K+ ++ +G + D I THFV+SF G P+DV++TR+MN + Y+G
Sbjct: 183 DQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSKG------EYQG 236
Query: 279 TVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
++ K G A YKG P +RL P ++ F+ EQL++
Sbjct: 237 VFHCAVETAK-LGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRK 279
Score = 37.0 bits (84), Expect = 0.024
Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 19/116 (16%)
Query: 17 ATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSID 76
A V+ +G+ +H ++ F+ GG A+ + + P+D+ KTRL
Sbjct: 185 AKQLVLSTGYLSDNIFTHFVAS-----FIAGGCATFLCQ----PLDVLKTRLMNS----- 230
Query: 77 ARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLF 132
+ +Y+G+FH K G LA Y G+ PA +R + + + L++ F
Sbjct: 231 ----KGEYQGVFHCAVETAKL-GPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNF 281
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 115 bits (288), Expect = 5e-26
Identities = 79/289 (27%), Positives = 139/289 (48%), Gaps = 14/289 (4%)
Query: 45 VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104
V G A +A T P+++ KTRLQ+QG+ Y G ++ + + +G+ L
Sbjct: 11 VLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQ 70
Query: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDV 164
G+A LL Q ++ Y + + + T+ + G V+G + + + +P +
Sbjct: 71 KGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTV----VAGAVAGALGAFVGSPAYL 126
Query: 165 LKIRMQAQ--GSLFQG------SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
+K ++QAQ ++ G +++G+ I++Q+G GLW+GV R + +L
Sbjct: 127 IKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLA 186
Query: 217 VYDITKKHLILSGMMG-DTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRA-IVGHVD 274
+ K + + D+ L +A + P DVV TR+ NQ G
Sbjct: 187 TFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQ 246
Query: 275 LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
LY G D ++K+W+ EG ALYKG P +LRLGP I+ + +++L++L
Sbjct: 247 LYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKL 295
Score = 50.1 bits (118), Expect = 3e-06
Identities = 37/168 (22%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 143 INMICGVVSGVISSTIANPTDVLKIRMQAQGSL---------FQGSMIGSFIDIYQQEGT 193
++++ G + ++ NP +V+K R+Q QG L + G I S + + +G
Sbjct: 8 VDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHG-FIASVAAVARADGL 66
Query: 194 RGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALAS 253
GL +G+ ++ GV Y + + L+ G T+ V+ G GA
Sbjct: 67 WGLQKGLAAGLLYQGLMNGVRFYCYSLACQ-AGLTQQPGGTV----VAGAVAGALGAFVG 121
Query: 254 NPVDVVRTRMMNQ---RAIVGHVDLYKGTVDGILKMWKHEGFFALYKG 298
+P +++T++ Q VGH ++ + + +W+ +G L++G
Sbjct: 122 SPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQG 169
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 107 bits (266), Expect = 2e-23
Identities = 79/284 (27%), Positives = 131/284 (46%), Gaps = 12/284 (4%)
Query: 41 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 100
WK + G +A V+ GT P+D K +QV + + + L + +E G
Sbjct: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN-------FTNLLGGLQSMVQEGGF 145
Query: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 160
+L+ G +L+ A IK +++ K F ++ G ++ IS T+ N
Sbjct: 146 RSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLIN 205
Query: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
P +VLK R+ + + ++ I Q+EGTR L+RG +P +L VY++
Sbjct: 206 PMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
Query: 221 TKKHLILSGM-MGDTILTHFVSSFTCG-LAGALASNPVDVVRTRMMNQRAIVGHVDLYKG 278
+ + SG MGD +SS T G +AS P+ +VRTRM Q + G +G
Sbjct: 266 LQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRG 325
Query: 279 TVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
+ IL +G+ LY+G P L++ P I ++ YE +K+
Sbjct: 326 VLQRIL---AQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/185 (27%), Positives = 90/185 (48%), Gaps = 15/185 (8%)
Query: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106
G LA +++ P+++ KTRL ++ +Y+G+ +I + EG ALY G
Sbjct: 193 GSLAVAISQTLINPMEVLKTRLTLRRTG--------QYKGLLDCARQILQREGTRALYRG 244
Query: 107 IAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANPTD 163
P +L Y + +Y+ L+ +V+ + D + L+++ +S + P
Sbjct: 245 YLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLT 304
Query: 164 VLKIRMQAQGSLFQGS---MIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
+++ RMQAQ ++ +GS M G I Q+G GL+RG+ PT + G+ VY+
Sbjct: 305 LVRTRMQAQDTV-EGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEA 363
Query: 221 TKKHL 225
KK L
Sbjct: 364 MKKTL 368
Score = 65.5 bits (158), Expect = 6e-11
Identities = 53/191 (27%), Positives = 88/191 (46%), Gaps = 21/191 (10%)
Query: 139 ETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQ-GSMIGSFIDIYQQEGTRGLW 197
E L ++ G ++G +S T P D K+ MQ S +++G + Q+ G R LW
Sbjct: 90 EALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLW 149
Query: 198 RGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALAS---- 253
RG + A ++ V++ K + G+ G + LAG+LA
Sbjct: 150 RGNGINVLKIAPEYAIKFSVFEQCKNYFC--GIQGSPPFQERL------LAGSLAVAISQ 201
Query: 254 ---NPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWN 310
NP++V++TR+ +R YKG +D ++ + EG ALY+G+ PN L + P+
Sbjct: 202 TLINPMEVLKTRLTLRRT-----GQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYA 256
Query: 311 IIFFITYEQLK 321
YE L+
Sbjct: 257 CTDLAVYEMLQ 267
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 211 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 266
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 267 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 321
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 322 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 381
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 382 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 440
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 441 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 278
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 279 GNGINVLKIAPESAIKFMAYEQIKRL 304
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 106 bits (264), Expect = 3e-23
Identities = 85/296 (28%), Positives = 135/296 (45%), Gaps = 22/296 (7%)
Query: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
K F+ GG+A+ +++ P++ K LQVQ S + +Y+G+ + RI KE+GVL
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADK-QYKGIVDCIVRIPKEQGVL 68
Query: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 156
+ + G ++R + K++F+ ++ T N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSL 128
Query: 157 TIANPTDVLKIRMQAQ----GSLFQGSMIGS-FIDIYQQEGTRGLWRGVVPTAQRAAIVV 211
P D + R+ A G+ + +G + I + +G RGL++G + Q I
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYR 188
Query: 212 GVELPVYDITKKHLILSGMMGDTILTHFVSSF----TCGLAGALASNPVDVVRTRMMNQR 267
VYD K GM+ D TH V S+ T + S P D VR RMM Q
Sbjct: 189 AAYFGVYDTAK------GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQS 242
Query: 268 AIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
G +Y GTVD K+++ EG A +KG W N LR G + Y++LK++
Sbjct: 243 GRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDELKKV 297
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 197 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 252
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 253 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 307
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 308 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 367
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 368 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 426
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 427 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 209 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 264
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 265 GNGINVLKIAPESAIKFMAYEQIKRL 290
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 74 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 129
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 130 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 184
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 185 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 244
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 245 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 303
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 304 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 86 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 141
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 142 GNGINVLKIAPESAIKFMAYEQIKRL 167
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 106 bits (264), Expect = 3e-23
Identities = 80/293 (27%), Positives = 139/293 (47%), Gaps = 16/293 (5%)
Query: 35 EMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRI 94
+++G+ WK V G +A V+ GT P+D K +QV + + L +
Sbjct: 180 KLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL-------NILGGLRSM 232
Query: 95 CKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVI 154
E G+ +L+ G +L+ A IK Y+ +KR + + E + + G ++G
Sbjct: 233 VLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGAT 292
Query: 155 SSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 214
+ TI P +VLK R+ + + ++ I ++EG R +RG +P G++
Sbjct: 293 AQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGID 352
Query: 215 LPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQRAIV 270
L VY+ T K+ L D+ + CG G +AS P+ +VRTRM Q +I
Sbjct: 353 LAVYE-TLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
Query: 271 GHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
G L ++ G+L+ + EG LY+G PN++++ P I ++ YE +K+
Sbjct: 412 GGPQL---SMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 94.0 bits (232), Expect = 2e-19
Identities = 58/189 (30%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
FV G LA A+ +P+++ KTRL ++ +Y+G+ RI + EG A
Sbjct: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG--------QYKGLLDCARRILEREGPRAF 334
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLE----DETLLINMICGVVSGVISSTIA 159
Y G P +L Y I + +Y++LK ++++ D +L+ + CG +S +
Sbjct: 335 YRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIAS 394
Query: 160 NPTDVLKIRMQAQGSLFQG---SMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
P +++ RMQAQ S+ G SM+G I QEG RGL+RG+ P + V +
Sbjct: 395 YPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYV 454
Query: 217 VYDITKKHL 225
VY+ K+ L
Sbjct: 455 VYENMKQAL 463
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 106 bits (264), Expect = 3e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 211 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 266
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 267 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 321
Query: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 322 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 381
Query: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 382 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 440
Query: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 441 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 37.7 bits (86), Expect = 0.014
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 223 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 278
Query: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
G N L++ P + I F+ YEQ+KRL
Sbjct: 279 GNGINVLKIAPESAIKFMAYEQIKRL 304
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 104 bits (260), Expect = 9e-23
Identities = 83/295 (28%), Positives = 134/295 (45%), Gaps = 22/295 (7%)
Query: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
K F+ GG+A+ +++ P++ K LQVQ S + +Y+G+ + RI KE+GVL
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK-QYKGIIDCVVRIPKEQGVL 68
Query: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 156
+ + G ++R + K++F+ ++ T N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
Query: 157 TIANPTDVLKIRMQAQ----GSLFQGSMIGS-FIDIYQQEGTRGLWRGVVPTAQRAAIVV 211
P D + R+ A G+ + +G + IY+ +G +GL++G + Q I
Sbjct: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
Query: 212 GVELPVYDITKKHLILSGMMGDTILTHFVSSF----TCGLAGALASNPVDVVRTRMMNQR 267
+YD K GM+ D TH V S+ T L S P D VR RMM Q
Sbjct: 189 AAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQS 242
Query: 268 AIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
G +Y GT+D K+ + EG A +KG W N LR G + Y+++K+
Sbjct: 243 GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 104 bits (260), Expect = 9e-23
Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
T + SG W+ + GG+A V+ T P+D K +QV G D +F
Sbjct: 185 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 237
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 150
++ KE G+ +L+ G +++ A +K Y+ K+L E + I G +
Sbjct: 238 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 297
Query: 151 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 210
+G + T P +V+K R+ + + I + EG ++G VP
Sbjct: 298 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 357
Query: 211 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 266
G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q
Sbjct: 358 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 416
Query: 267 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
+ G L V ++ EG LY+G PN++++ P I ++ YE +K+
Sbjct: 417 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 88.6 bits (218), Expect = 7e-18
Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 343
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 159
Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S +
Sbjct: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403
Query: 160 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+
Sbjct: 404 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 463
Query: 217 VYDITKKHL 225
VY+ K+ L
Sbjct: 464 VYENMKQTL 472
Score = 31.6 bits (70), Expect = 1.0
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 246 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 302
G+AGA++ P+D ++ M + ++++ G +M K G +L++G N
Sbjct: 202 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 257
Query: 303 WLRLGPWNIIFFITYEQLKRL 323
+++ P + F YEQ K+L
Sbjct: 258 VIKIAPETAVKFWAYEQYKKL 278
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 104 bits (260), Expect = 9e-23
Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%)
Query: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
T + SG W+ + GG+A V+ T P+D K +QV G D +F
Sbjct: 166 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 218
Query: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 150
++ KE G+ +L+ G +++ A +K Y+ K+L E + I G +
Sbjct: 219 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 278
Query: 151 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 210
+G + T P +V+K R+ + + I + EG ++G VP
Sbjct: 279 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 338
Query: 211 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 266
G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q
Sbjct: 339 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 397
Query: 267 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
+ G L V ++ EG LY+G PN++++ P I ++ YE +K+
Sbjct: 398 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 88.6 bits (218), Expect = 7e-18
Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 324
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 159
Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S +
Sbjct: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Query: 160 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+
Sbjct: 385 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 444
Query: 217 VYDITKKHL 225
VY+ K+ L
Sbjct: 445 VYENMKQTL 453
Score = 31.6 bits (70), Expect = 1.0
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 246 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 302
G+AGA++ P+D ++ M + ++++ G +M K G +L++G N
Sbjct: 183 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 238
Query: 303 WLRLGPWNIIFFITYEQLKRL 323
+++ P + F YEQ K+L
Sbjct: 239 VIKIAPETAVKFWAYEQYKKL 259
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 101 bits (252), Expect = 8e-22
Identities = 78/280 (27%), Positives = 124/280 (44%), Gaps = 7/280 (2%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F G +A V +P+DL KTR+Q Q S + E+ Y+ F ++ + EG L
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGS-GSVVGELMYKNSFDCFKKVLRYEGFFGL 388
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163
Y G+ P L+ A IK+ + ++ F R L ++ G +G NP +
Sbjct: 389 YRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLE 448
Query: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223
++KIR+Q G + G + S +++ + G GL++G R + PVY K
Sbjct: 449 IVKIRLQVAGEITTGPRV-SALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCK- 506
Query: 224 HLILSGMMGDT-ILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282
L+L+ G L + G+ A P DV++TR+ Q A Y G +D
Sbjct: 507 -LLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 563
Query: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
K+ + EG A +KG R P + +TYE L+R
Sbjct: 564 FRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
Score = 59.3 bits (142), Expect = 4e-09
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 16/184 (8%)
Query: 148 GVVSGVISSTIANPTDVLKIRMQAQ-------GSLFQGSMIGSFIDIYQQEGTRGLWRGV 200
G V+G + +T P D++K RMQ Q G L + F + + EG GL+RG+
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 201 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC-GLAGALASNPVDVV 259
+P A ++L V D + G L V + C G + + +NP+++V
Sbjct: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRD--GSVPLPAEVLAGGCAGGSQVIFTNPLEIV 450
Query: 260 RTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ 319
+ R+ + G + G L + + G F LYKG +LR P++ I+F Y
Sbjct: 451 KIRLQ----VAGEITT--GPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAH 504
Query: 320 LKRL 323
K L
Sbjct: 505 CKLL 508
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 10/134 (7%)
Query: 2 GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHE--MSGLNWKPFVYGGLASIVAEFGT 58
G++ G FLR + F+ V H K + GLN G +A + A
Sbjct: 479 GLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNL--LAAGAMAGVPAASLV 536
Query: 59 FPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYG 118
P D+ KTRLQV AR + Y G+ +I +EEG A + G A + R +
Sbjct: 537 TPADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQF 591
Query: 119 TIKIGIYQSLKRLF 132
+ + Y+ L+R F
Sbjct: 592 GVTLVTYELLQRWF 605
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 100 bits (248), Expect = 2e-21
Identities = 81/285 (28%), Positives = 135/285 (47%), Gaps = 18/285 (6%)
Query: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
+ V GG A +V P+D+ KTR Q+Q + D Y+ + + I + EG+
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPN----SYKSLVDSFRMIFQMEGLF 70
Query: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANP 161
Y GI P +L + +K ++ K+L + + L I G+ SG+ + + NP
Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKL-LGYVSLSPALTFAIAGLGSGLTEAIVVNP 129
Query: 162 TDVLKIRMQAQGSLF--QGSMIGSFIDIYQQEG--TRGLWRGVVPTAQRAAIVVGVELPV 217
+V+K+ +QA + F Q S +G I ++EG +GL +G+ T R + V
Sbjct: 130 FEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGF 189
Query: 218 YDITKKHLILSGMMGDTILTHFVSSFTCGL-AGALASN---PVDVVRTRMMNQRAIVGHV 273
Y K + ++ D IL F F GL +G +AS P DV ++R+ + + G +
Sbjct: 190 YYNVKNMIPVNK---DPIL-EFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEI 245
Query: 274 DLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318
Y+ + +++ EG ALYKG P +RLGP + + YE
Sbjct: 246 K-YRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289
Score = 55.8 bits (133), Expect = 5e-08
Identities = 46/183 (25%), Positives = 80/183 (43%), Gaps = 7/183 (3%)
Query: 145 MICGVVSGVISSTIANPTDVLKIRMQAQGSLFQG----SMIGSFIDIYQQEGTRGLWRGV 200
++ G +G++ + +P DV+K R Q Q S++ SF I+Q EG G ++G+
Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGI 76
Query: 201 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVR 260
+P V+ ++ KK +L + LT ++ GL A+ NP +VV+
Sbjct: 77 LPPILAETPKRAVKFFTFEQYKK--LLGYVSLSPALTFAIAGLGSGLTEAIVVNPFEVVK 134
Query: 261 TRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 320
+ R G I+K + G L KG R G +N+++F Y +
Sbjct: 135 VGLQANRNTFAEQPSTVGYARQIIKK-EGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNV 193
Query: 321 KRL 323
K +
Sbjct: 194 KNM 196
Score = 54.7 bits (130), Expect = 1e-07
Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 41 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 100
W+ F G L+ +A P D+ K+R+Q Q + EIKYR F + + +EEG+
Sbjct: 208 WRKFGIGLLSGTIASVINIPFDVAKSRIQGP-QPVPG---EIKYRTCFKTMATVYQEEGI 263
Query: 101 LALYSGIAPALLRQASYGTIKIGIYQ 126
LALY G+ P ++R G + + +Y+
Sbjct: 264 LALYKGLLPKIMRLGPGGAVMLLVYE 289
Score = 49.7 bits (117), Expect = 4e-06
Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 16/187 (8%)
Query: 44 FVYGGLASIVAE-FGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEG--V 100
F GL S + E P ++ K LQ + + + Y +I K+EG +
Sbjct: 112 FAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYAR------QIIKKEGWGL 165
Query: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTI 158
L G+ L R + + G Y ++K + +D L G++SG I+S I
Sbjct: 166 QGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVN-KDPILEFWRKFGIGLLSGTIASVI 224
Query: 159 ANPTDVLKIRMQAQ----GSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVE 214
P DV K R+Q G + + + +YQ+EG L++G++P R V
Sbjct: 225 NIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVM 284
Query: 215 LPVYDIT 221
L VY+ T
Sbjct: 285 LLVYEYT 291
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 99.4 bits (246), Expect = 4e-21
Identities = 85/297 (28%), Positives = 130/297 (43%), Gaps = 26/297 (8%)
Query: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
K F+ GG+A+ V++ P++ K LQVQ S E +Y+G+ + RI KE+G L
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQIS-AEKQYKGIIDCVVRIPKEQGFL 68
Query: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI-----NMICGVVSGVISS 156
+ + G ++R + K+LF+ ++ N+ G +G S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSL 128
Query: 157 TIANPTDVLKIRMQAQGSLFQGSMIGSF-------IDIYQQEGTRGLWRGVVPTAQRAAI 209
P D + R+ A + +G+ F I I++ +G RGL++G + Q I
Sbjct: 129 CFVYPLDFARTRLAAD--VGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
Query: 210 VVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLA----GALASNPVDVVRTRMMN 265
VYD K GM+ D H S+ + L S P D VR RMM
Sbjct: 187 YRAAYFGVYDTAK------GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMM 240
Query: 266 QRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Q G +Y GTVD K+ K EG A +KG W N LR G + Y+++K+
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Score = 35.8 bits (81), Expect = 0.053
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 231 MGDTILTHFVSSFTCGLAGALASN---PVDVVRTRMMNQRAI--VGHVDLYKGTVDGILK 285
MGD + G+A A++ P++ V+ + Q A + YKG +D +++
Sbjct: 1 MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVR 60
Query: 286 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
+ K +GF + ++G N +R P + F ++ K+L
Sbjct: 61 IPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQL 98
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 98.6 bits (244), Expect = 7e-21
Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F G +A V +P+DL KTR+Q Q +S + E+ Y+ F ++ + EG L
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163
Y G+ P LL A IK+ + ++ F+ + L ++ G +G NP +
Sbjct: 391 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 450
Query: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223
++KIR+Q G + G + S + + + G G+++G R + P Y K
Sbjct: 451 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 509
Query: 224 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282
G + L ++ G+ A P DV++TR+ Q A Y G +D
Sbjct: 510 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 565
Query: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
K+ + EG AL+KG R P + +TYE L+R
Sbjct: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
Score = 46.2 bits (108), Expect = 4e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 6/132 (4%)
Query: 2 GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
GI+ G FLR + F+ H K++ + + + G +A + A P
Sbjct: 481 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 540
Query: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
D+ KTRLQV AR + Y G+ +I +EEG AL+ G + R + +
Sbjct: 541 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 595
Query: 121 KIGIYQSLKRLF 132
+ Y+ L+R F
Sbjct: 596 TLLTYELLQRWF 607
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 98.6 bits (244), Expect = 7e-21
Identities = 75/280 (26%), Positives = 123/280 (43%), Gaps = 7/280 (2%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
F G +A V +P+DL KTR+Q Q +S + E+ Y+ F ++ + EG L
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQ-RSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTD 163
Y G+ P LL A IK+ + ++ F+ + L ++ G +G NP +
Sbjct: 392 YRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLE 451
Query: 164 VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223
++KIR+Q G + G + S + + + G G+++G R + P Y K
Sbjct: 452 IVKIRLQVAGEITTGPRV-SALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKA 510
Query: 224 HLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDG 282
G + L ++ G+ A P DV++TR+ Q A Y G +D
Sbjct: 511 SFANEDGQVSPGSL--LLAGAIAGMPAASLVTPADVIKTRL--QVAARAGQTTYSGVIDC 566
Query: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
K+ + EG AL+KG R P + +TYE L+R
Sbjct: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606
Score = 46.2 bits (108), Expect = 4e-05
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 6/132 (4%)
Query: 2 GIFPGIILIFLR-VKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
GI+ G FLR + F+ H K++ + + + G +A + A P
Sbjct: 482 GIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTP 541
Query: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
D+ KTRLQV AR + Y G+ +I +EEG AL+ G + R + +
Sbjct: 542 ADVIKTRLQVA-----ARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGV 596
Query: 121 KIGIYQSLKRLF 132
+ Y+ L+R F
Sbjct: 597 TLLTYELLQRWF 608
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 96.3 bits (238), Expect = 3e-20
Identities = 71/287 (24%), Positives = 128/287 (44%), Gaps = 15/287 (5%)
Query: 45 VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104
V G ++ +V P D+ K R Q+Q + + KY G+ A +I +EEG A +
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANP 161
G PA + YG ++ ++ L L V R + ++ +CG ++ +++ +P
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTEL-VHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 162 TDVLKIRMQAQGS-LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
DVL+ R AQG ++ + +Y+ EG + ++G+ PT G++ Y
Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS- 197
Query: 221 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASN----PVDVVRTRMM-----NQRAIVG 271
+ KHL + + + + CG + S P+D+ + R+ + RA G
Sbjct: 198 SLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
Query: 272 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318
V YKG +D ++ + EG +KG P+ L+ F +YE
Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 23/184 (12%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
FV GGLA+ +A PVD+ +TR QG+ Y + HA+ + + EG
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLF-----VERLEDETLLINMICGVVSGVISSTI 158
Y G+AP L+ Y ++ Y SLK L+ E ++E L N++CG +GVIS T+
Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQ-NLLCGSGAGVISKTL 233
Query: 159 ANPTDVLKIRMQAQGSLFQGSMIGSF----------IDIYQQEGTRGLWRGVVPTAQRAA 208
P D+ K R+Q G + G + Q+EG G ++G+ P+ +AA
Sbjct: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
Query: 209 IVVG 212
+ G
Sbjct: 294 LSTG 297
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/78 (32%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Query: 40 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQG-QSIDARFKEI-KYRGMFHALFRICKE 97
N + + G A ++++ T+P+DL K RLQV G + A F ++ +Y+G+ ++ ++
Sbjct: 216 NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQK 275
Query: 98 EGVLALYSGIAPALLRQA 115
EG L + G++P+LL+ A
Sbjct: 276 EGALGFFKGLSPSLLKAA 293
Score = 29.6 bits (65), Expect = 3.8
Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 240 VSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD---LYKGTVDGILKMWKHEGFFALY 296
V+ GL +P DV++ R Q + D Y G + ++ + EG A +
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 297 KGFWPNWLRLGPWNIIFFITYEQLKRL 323
KG P + + + F+++E L L
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTEL 106
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 96.3 bits (238), Expect = 3e-20
Identities = 71/287 (24%), Positives = 128/287 (44%), Gaps = 15/287 (5%)
Query: 45 VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104
V G ++ +V P D+ K R Q+Q + + KY G+ A +I +EEG A +
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVER---LEDETLLINMICGVVSGVISSTIANP 161
G PA + YG ++ ++ L L V R + ++ +CG ++ +++ +P
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTEL-VHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 162 TDVLKIRMQAQGS-LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220
DVL+ R AQG ++ + +Y+ EG + ++G+ PT G++ Y
Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS- 197
Query: 221 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASN----PVDVVRTRMM-----NQRAIVG 271
+ KHL + + + + CG + S P+D+ + R+ + RA G
Sbjct: 198 SLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
Query: 272 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318
V YKG +D ++ + EG +KG P+ L+ F +YE
Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 84.3 bits (207), Expect = 1e-16
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 23/184 (12%)
Query: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
FV GGLA+ +A PVD+ +TR QG+ Y + HA+ + + EG
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
Query: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLF-----VERLEDETLLINMICGVVSGVISSTI 158
Y G+AP L+ Y ++ Y SLK L+ E ++E L N++CG +GVIS T+
Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQ-NLLCGSGAGVISKTL 233
Query: 159 ANPTDVLKIRMQAQGSLFQGSMIGSF----------IDIYQQEGTRGLWRGVVPTAQRAA 208
P D+ K R+Q G + G + Q+EG G ++G+ P+ +AA
Sbjct: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
Query: 209 IVVG 212
+ G
Sbjct: 294 LSTG 297
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/78 (32%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Query: 40 NWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQG-QSIDARFKEI-KYRGMFHALFRICKE 97
N + + G A ++++ T+P+DL K RLQV G + A F ++ +Y+G+ ++ ++
Sbjct: 216 NLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQK 275
Query: 98 EGVLALYSGIAPALLRQA 115
EG L + G++P+LL+ A
Sbjct: 276 EGALGFFKGLSPSLLKAA 293
Score = 29.6 bits (65), Expect = 3.8
Identities = 21/87 (24%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 240 VSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVD---LYKGTVDGILKMWKHEGFFALY 296
V+ GL +P DV++ R Q + D Y G + ++ + EG A +
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 297 KGFWPNWLRLGPWNIIFFITYEQLKRL 323
KG P + + + F+++E L L
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTEL 106
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,557,164
Number of Sequences: 37866
Number of extensions: 404581
Number of successful extensions: 1826
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1089
Number of HSP's gapped (non-prelim): 209
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.