Search of human proteins with 4506489

Search of human proteins with 4506489

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
         (356 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]            717   0.0  
gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]          593   e-170
gi|31881687 replication factor C 4 [Homo sapiens]                     113   3e-25
gi|4506491 replication factor C 4 [Homo sapiens]                      113   3e-25
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]            104   1e-22
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]           103   3e-22
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]          100   3e-21
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]          100   3e-21
gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]           71   2e-12
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]            58   1e-08
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]                     39   0.009
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]                     39   0.009
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]                     39   0.009
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]                     39   0.009
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]                      39   0.009
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]                     39   0.009
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ...    31   1.9  
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ...    31   1.9  
gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sa...    30   2.5  
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]             29   5.6  
gi|4505187 small inducible cytokine B9 precursor [Homo sapiens]        29   7.4  
gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens]     29   7.4  
gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens]     29   7.4  
gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens]      29   7.4  
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap...    28   9.6  
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]    28   9.6  
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]    28   9.6  
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]    28   9.6  
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]    28   9.6  

>gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
          Length = 356

 Score =  717 bits (1852), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 60
           MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY
Sbjct: 1   MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 60

Query: 61  GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 120
           GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ
Sbjct: 61  GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 120

Query: 121 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 180
           LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL
Sbjct: 121 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 180

Query: 181 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 240
           AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF
Sbjct: 181 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 240

Query: 241 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL 300
           TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL
Sbjct: 241 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL 300

Query: 301 HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF 356
           HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF
Sbjct: 301 HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF 356


>gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]
          Length = 305

 Score =  593 bits (1529), Expect = e-170
 Identities = 296/304 (97%), Positives = 297/304 (97%), Gaps = 1/304 (0%)

Query: 1   MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 60
           MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY
Sbjct: 1   MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 60

Query: 61  GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 120
           GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ
Sbjct: 61  GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 120

Query: 121 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 180
           LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL
Sbjct: 121 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 180

Query: 181 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 240
           AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF
Sbjct: 181 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 240

Query: 241 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL 300
           TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMK    E  
Sbjct: 241 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKACKEE-S 299

Query: 301 HNCD 304
            +CD
Sbjct: 300 RSCD 303


>gi|31881687 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  113 bits (282), Expect = 3e-25
 Identities = 77/233 (33%), Positives = 113/233 (48%), Gaps = 29/233 (12%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
           WV+KYRP  +  + + +E  A L+  ++  D P+LL YGP G GK + I+   REL+G  
Sbjct: 40  WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPE 99

Query: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
           + +LR+                       LE+N SD       V++E +K  AQ     +
Sbjct: 100 LFRLRV-----------------------LELNASDERGIQ--VVREKVKNFAQLTVSGS 134

Query: 124 NSQRD----FKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRC 179
            S       FK+V+L E D +T  AQ ALRRTMEK   T R  L CN  S++I P+ SRC
Sbjct: 135 RSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 194

Query: 180 LAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEA 232
              R    S +     L  + KKE + +  +    L + S  +LRKA+   ++
Sbjct: 195 SKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS 247


>gi|4506491 replication factor C 4 [Homo sapiens]
          Length = 363

 Score =  113 bits (282), Expect = 3e-25
 Identities = 77/233 (33%), Positives = 113/233 (48%), Gaps = 29/233 (12%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
           WV+KYRP  +  + + +E  A L+  ++  D P+LL YGP G GK + I+   REL+G  
Sbjct: 40  WVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPE 99

Query: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
           + +LR+                       LE+N SD       V++E +K  AQ     +
Sbjct: 100 LFRLRV-----------------------LELNASDERGIQ--VVREKVKNFAQLTVSGS 134

Query: 124 NSQRD----FKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRC 179
            S       FK+V+L E D +T  AQ ALRRTMEK   T R  L CN  S++I P+ SRC
Sbjct: 135 RSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRC 194

Query: 180 LAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEA 232
              R    S +     L  + KKE + +  +    L + S  +LRKA+   ++
Sbjct: 195 SKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQS 247


>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
          Length = 340

 Score =  104 bits (259), Expect = 1e-22
 Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 28/224 (12%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
           WV+KYRP +L  L  H++  + ++  +     PHLL+YGP G GK + I+   ++LY   
Sbjct: 22  WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY--- 78

Query: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
                           K  E  ++     LE+N SD    D  +I+  + + A ++   T
Sbjct: 79  ----------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---T 113

Query: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183
             ++ FK+V+L E D +T+DAQ+ALRR +EK+    R  L CN  SK+IP ++SRC   R
Sbjct: 114 IFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFR 173

Query: 184 VPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227
               + E +   L  V ++E +++       L   S  ++R+AL
Sbjct: 174 FGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 217


>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
          Length = 354

 Score =  103 bits (256), Expect = 3e-22
 Identities = 65/200 (32%), Positives = 99/200 (49%), Gaps = 28/200 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
           WV+KYRP  L  +  +++  ++L    + G+ P++++ GP G GK T I+C+ R L G  
Sbjct: 38  WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97

Query: 64  VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
           ++                           LE+N S+    D  V++  +K  AQ  Q  T
Sbjct: 98  LKDAM------------------------LELNASNDRGID--VVRNKIKMFAQ--QKVT 129

Query: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183
             +   K+++L E D +T  AQ ALRRTME Y  T R  L CN++ K+I PI+SRC  +R
Sbjct: 130 LPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLR 189

Query: 184 VPAPSIEDICHVLSTVCKKE 203
               +   I   L  V +KE
Sbjct: 190 YTKLTDAQILTRLMNVIEKE 209


>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/223 (30%), Positives = 113/223 (50%), Gaps = 28/223 (12%)

Query: 5   VDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGV 64
           V+KYRP +L  L  H++  + ++  +     PHLL+YGP G GK + I+   ++LY    
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY---- 57

Query: 65  EKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETN 124
                          K  E  ++     LE+N SD    D  +I+  + + A ++   T 
Sbjct: 58  ---------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---TI 93

Query: 125 SQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRV 184
            ++ FK+V+L E D +T+DAQ+ALRR +EK+    R  L CN  SK+IP ++SRC   R 
Sbjct: 94  FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 153

Query: 185 PAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227
              + E +   L  V ++E +++       L   S  ++R+AL
Sbjct: 154 GPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 196


>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/223 (30%), Positives = 113/223 (50%), Gaps = 28/223 (12%)

Query: 5   VDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGV 64
           V+KYRP +L  L  H++  + ++  +     PHLL+YGP G GK + I+   ++LY    
Sbjct: 2   VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY---- 57

Query: 65  EKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETN 124
                          K  E  ++     LE+N SD    D  +I+  + + A ++   T 
Sbjct: 58  ---------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---TI 93

Query: 125 SQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRV 184
            ++ FK+V+L E D +T+DAQ+ALRR +EK+    R  L CN  SK+IP ++SRC   R 
Sbjct: 94  FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRF 153

Query: 185 PAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227
              + E +   L  V ++E +++       L   S  ++R+AL
Sbjct: 154 GPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 196


>gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]
          Length = 255

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 46/135 (34%), Positives = 75/135 (55%), Gaps = 5/135 (3%)

Query: 93  LEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTM 152
           LE+N SD    D  +I+  + + A ++   T  ++ FK+V+L E D +T+DAQ+ALRR +
Sbjct: 3   LELNASDDRGID--IIRGPILSFASTR---TIFKKGFKLVILDEADAMTQDAQNALRRVI 57

Query: 153 EKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLA 212
           EK+    R  L CN  SK+IP ++SRC   R    + E +   L  V ++E +++     
Sbjct: 58  EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 117

Query: 213 HRLAEKSCRNLRKAL 227
             L   S  ++R+AL
Sbjct: 118 KALVTLSSGDMRRAL 132


>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
          Length = 320

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 32/77 (41%), Positives = 42/77 (54%)

Query: 127 RDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPA 186
           +D  + L    D +T  AQ ALRRTME Y  T R  L CN++ K+I PI+SRC  +R   
Sbjct: 99  KDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTK 158

Query: 187 PSIEDICHVLSTVCKKE 203
            +   I   L  V +KE
Sbjct: 159 LTDAQILTRLMNVIEKE 175



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 8/104 (7%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
           WV+KYRP  L  +  +++  ++L    + G+ P++++ GP G GK T I+C+ R L G  
Sbjct: 38  WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97

Query: 64  VE----KLRIEHQTITTPS----KKKIEISTIASNYHLEVNPSD 99
           ++    +L   + ++T  +    ++ +EI +  + + L  N SD
Sbjct: 98  LKDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASD 141


>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 80  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 140 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 189

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 190 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 244


>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 80  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 140 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 189

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 190 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 244


>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 80  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 140 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 189

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 190 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 244


>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 80  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 140 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 189

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 190 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 244


>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
          Length = 670

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 80  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 140 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 189

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 190 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 244


>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
          Length = 681

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 4   WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPH--------LLVYGPSGAGKKTRIMCI 55
           WVDKY+P +   L  HK++  ++   ++              LL+ GP G GK T +  +
Sbjct: 91  WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 150

Query: 56  LRELYGVGVEKLRIEHQTITTPSKKKIEIS---TIASNYHLEVNPSDAGNSDRVVIQEML 112
            +E +G+ V+    E      P  +K +        S++H+    S        V +E L
Sbjct: 151 SKE-HGIQVQ----EWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQI-----AVFKEFL 200

Query: 113 KTVA---QSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKY--MSTCRLI 162
                  + Q L  + + D K++L+ ++        H L   + KY  +  C LI
Sbjct: 201 LRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLI 255


>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 22  QAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKK 81
           Q   LR+L++  + P L+++GP G GK T     L  +     +K  I   T++  + K 
Sbjct: 248 QDTLLRSLLETNEIPSLILWGPPGCGKTT-----LAHIIASNSKKHSIRFVTLSATNAKT 302

Query: 82  IEISTI 87
            ++  +
Sbjct: 303 NDVRDV 308


>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 22  QAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKK 81
           Q   LR+L++  + P L+++GP G GK T     L  +     +K  I   T++  + K 
Sbjct: 248 QDTLLRSLLETNEIPSLILWGPPGCGKTT-----LAHIIASNSKKHSIRFVTLSATNAKT 302

Query: 82  IEISTI 87
            ++  +
Sbjct: 303 NDVRDV 308


>gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo
           sapiens]
          Length = 842

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 8/62 (12%)

Query: 38  LLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNP 97
           L + GPSGAGK T I+ +L   Y +    +RI+ Q I+       +++  +   H+ V P
Sbjct: 619 LALVGPSGAGKST-ILRLLFRFYDISSGCIRIDGQDIS-------QVTQASLRSHIGVVP 670

Query: 98  SD 99
            D
Sbjct: 671 QD 672


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 38   LLVYGPSGAGKKTRIMCILRELYGVGV--EKLRIEHQTITTP 77
            ++  GPSGAGK T I  ++R +   G    ++R+  + IT P
Sbjct: 2258 MMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAP 2299


>gi|4505187 small inducible cytokine B9 precursor [Homo sapiens]
          Length = 125

 Score = 28.9 bits (63), Expect = 7.4
 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 3/87 (3%)

Query: 48  KKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIE-ISTIASNYHLEVNPSDAGNSDRV 106
           +K R  CI      + ++ L+   Q   +PS +KIE I+T+ +     +NP  A   +  
Sbjct: 27  RKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKNGVQTCLNPDSADVKE-- 84

Query: 107 VIQEMLKTVAQSQQLETNSQRDFKVVL 133
           +I++  K V+Q ++ +   +   K VL
Sbjct: 85  LIKKWEKQVSQKKKQKNGKKHQKKKVL 111


>gi|116284382 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score = 28.9 bits (63), Expect = 7.4
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%)

Query: 180 LAVRVPAPS---IEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEAC 233
           L+VRV A +   ++DIC +   VC+ E    PS LA  L  +  R    A+L+   C
Sbjct: 184 LSVRVLATAHRQLQDICRLERAVCRDE----PSALARALTWRQARAQAGAMLLFGLC 236


>gi|116284384 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score = 28.9 bits (63), Expect = 7.4
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%)

Query: 180 LAVRVPAPS---IEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEAC 233
           L+VRV A +   ++DIC +   VC+ E    PS LA  L  +  R    A+L+   C
Sbjct: 184 LSVRVLATAHRQLQDICRLERAVCRDE----PSALARALTWRQARAQAGAMLLFGLC 236


>gi|24850109 G protein-coupled bile acid receptor 1 [Homo sapiens]
          Length = 330

 Score = 28.9 bits (63), Expect = 7.4
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%)

Query: 180 LAVRVPAPS---IEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEAC 233
           L+VRV A +   ++DIC +   VC+ E    PS LA  L  +  R    A+L+   C
Sbjct: 184 LSVRVLATAHRQLQDICRLERAVCRDE----PSALARALTWRQARAQAGAMLLFGLC 236


>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
           sapiens]
          Length = 1025

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 174 PIRSRCLAVRVPAPSIEDIC-HVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEA 232
           P++  C   + P P+I+D+    L  +     L+   Q+   + E+ C N  K  + C  
Sbjct: 906 PLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCYMTCND 965

Query: 233 CRVQQYPFTADQEIP 247
              Q   F  +  +P
Sbjct: 966 SGYQAIQFDPETHLP 980


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 51/210 (24%)

Query: 85  STIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDA 144
           ST+  N H+       G    V+    LK    ++ L+T S+  F +         T +A
Sbjct: 112 STVPQNQHIT-----NGTLTGVLSLSELKRSELNKTLQTLSETYFIMCA-------TAEA 159

Query: 145 QHALRRT----MEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVC 200
           Q  L  T    +   M+ C +I         I P+   C +VR+P PS            
Sbjct: 160 QSTLNCTFTIKLNNTMNACAVIAALERVK--IRPMEHCCCSVRIPCPS------------ 205

Query: 201 KKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETAN 260
                  P +L     EK   +L+   ++C A   +  PF++ Q IP       L +   
Sbjct: 206 ------SPEEL-----EKLQCDLQDP-IVCLADHPRGPPFSSSQSIPVVPRATVLSQVPK 253

Query: 261 AIVSQQTPQRLLEVRGRLYELLTHCIPPEI 290
           A    + P          Y  +TH +P  I
Sbjct: 254 ATSFAEPPD---------YSPVTHNVPSPI 274


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 51/210 (24%)

Query: 85  STIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDA 144
           ST+  N H+       G    V+    LK    ++ L+T S+  F +         T +A
Sbjct: 120 STVPQNQHIT-----NGTLTGVLSLSELKRSELNKTLQTLSETYFIMCA-------TAEA 167

Query: 145 QHALRRT----MEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVC 200
           Q  L  T    +   M+ C +I         I P+   C +VR+P PS            
Sbjct: 168 QSTLNCTFTIKLNNTMNACAVIAALERVK--IRPMEHCCCSVRIPCPS------------ 213

Query: 201 KKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETAN 260
                  P +L     EK   +L+   ++C A   +  PF++ Q IP       L +   
Sbjct: 214 ------SPEEL-----EKLQCDLQDP-IVCLADHPRGPPFSSSQSIPVVPRATVLSQVPK 261

Query: 261 AIVSQQTPQRLLEVRGRLYELLTHCIPPEI 290
           A    + P          Y  +TH +P  I
Sbjct: 262 ATSFAEPPD---------YSPVTHNVPSPI 282


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 51/210 (24%)

Query: 85  STIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDA 144
           ST+  N H+       G    V+    LK    ++ L+T S+  F +         T +A
Sbjct: 134 STVPQNQHIT-----NGTLTGVLSLSELKRSELNKTLQTLSETYFIMCA-------TAEA 181

Query: 145 QHALRRT----MEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVC 200
           Q  L  T    +   M+ C +I         I P+   C +VR+P PS            
Sbjct: 182 QSTLNCTFTIKLNNTMNACAVIAALERVK--IRPMEHCCCSVRIPCPS------------ 227

Query: 201 KKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETAN 260
                  P +L     EK   +L+   ++C A   +  PF++ Q IP       L +   
Sbjct: 228 ------SPEEL-----EKLQCDLQDP-IVCLADHPRGPPFSSSQSIPVVPRATVLSQVPK 275

Query: 261 AIVSQQTPQRLLEVRGRLYELLTHCIPPEI 290
           A    + P          Y  +TH +P  I
Sbjct: 276 ATSFAEPPD---------YSPVTHNVPSPI 296


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 51/210 (24%)

Query: 85  STIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDA 144
           ST+  N H+       G    V+    LK    ++ L+T S+  F +         T +A
Sbjct: 131 STVPQNQHIT-----NGTLTGVLSLSELKRSELNKTLQTLSETYFIMCA-------TAEA 178

Query: 145 QHALRRT----MEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVC 200
           Q  L  T    +   M+ C +I         I P+   C +VR+P PS            
Sbjct: 179 QSTLNCTFTIKLNNTMNACAVIAALERVK--IRPMEHCCCSVRIPCPS------------ 224

Query: 201 KKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETAN 260
                  P +L     EK   +L+   ++C A   +  PF++ Q IP       L +   
Sbjct: 225 ------SPEEL-----EKLQCDLQDP-IVCLADHPRGPPFSSSQSIPVVPRATVLSQVPK 272

Query: 261 AIVSQQTPQRLLEVRGRLYELLTHCIPPEI 290
           A    + P          Y  +TH +P  I
Sbjct: 273 ATSFAEPPD---------YSPVTHNVPSPI 293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,212,365
Number of Sequences: 37866
Number of extensions: 569344
Number of successful extensions: 1471
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1440
Number of HSP's gapped (non-prelim): 30
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.