Search of human proteins with 4506061

Search of human proteins with 4506061

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1
subunit isoform 1 [Homo sapiens]
         (331 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1 su...   652   0.0  
gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1 s...   486   e-137
gi|100913192 AMP-activated protein kinase gamma2 subunit isoform...   473   e-134
gi|100913189 AMP-activated protein kinase gamma2 subunit isoform...   473   e-134
gi|33186925 AMP-activated protein kinase gamma2 subunit isoform ...   473   e-134
gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3 ...   396   e-110
gi|170763513 ATP/GTP binding protein 1 [Homo sapiens]                  30   3.9  
gi|157388965 schlafen family member 11 [Homo sapiens]                  29   5.1  
gi|157388963 schlafen family member 11 [Homo sapiens]                  29   5.1  
gi|157388961 schlafen family member 11 [Homo sapiens]                  29   5.1  
gi|157388959 schlafen family member 11 [Homo sapiens]                  29   5.1  
gi|157388957 schlafen family member 11 [Homo sapiens]                  29   5.1  
gi|56119108 schlafen family member 13 [Homo sapiens]                   29   5.1  

>gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 1 [Homo sapiens]
          Length = 331

 Score =  652 bits (1681), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA 60
           METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
Sbjct: 1   METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA 60

Query: 61  FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV 120
           FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV
Sbjct: 61  FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV 120

Query: 121 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI 180
           YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI
Sbjct: 121 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI 180

Query: 181 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI 240
           TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI
Sbjct: 181 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI 240

Query: 241 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL 300
           YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL
Sbjct: 241 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL 300

Query: 301 VVVDENDVVKGIVSLSDILQALVLTGGEKKP 331
           VVVDENDVVKGIVSLSDILQALVLTGGEKKP
Sbjct: 301 VVVDENDVVKGIVSLSDILQALVLTGGEKKP 331


>gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 2 [Homo sapiens]
          Length = 247

 Score =  486 bits (1250), Expect = e-137
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 85  MLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSS 144
           MLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSS
Sbjct: 1   MLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSS 60

Query: 145 LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANI 204
           LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANI
Sbjct: 61  LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANI 120

Query: 205 AMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTK 264
           AMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTK
Sbjct: 121 AMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTK 180

Query: 265 ALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 324
           ALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL
Sbjct: 181 ALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 240

Query: 325 TGGEKKP 331
           TGGEKKP
Sbjct: 241 TGGEKKP 247


>gi|100913192 AMP-activated protein kinase gamma2 subunit isoform c
           [Homo sapiens]
          Length = 525

 Score =  473 bits (1218), Expect = e-134
 Identities = 233/303 (76%), Positives = 270/303 (89%)

Query: 23  ESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSF 82
           +S + VY  FM+SH+CYD++PTSSKLVVFDT+LQVKKAFFALV NGVRAAPLW+SKKQSF
Sbjct: 211 DSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSF 270

Query: 83  VGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAV 142
           VGMLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV
Sbjct: 271 VGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAV 330

Query: 143 SSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202
            SLI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY 
Sbjct: 331 YSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYH 390

Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262
           NIA +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++V
Sbjct: 391 NIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITV 450

Query: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322
           T+ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL
Sbjct: 451 TQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQAL 510

Query: 323 VLT 325
           +LT
Sbjct: 511 ILT 513


>gi|100913189 AMP-activated protein kinase gamma2 subunit isoform b
           [Homo sapiens]
          Length = 328

 Score =  473 bits (1218), Expect = e-134
 Identities = 233/303 (76%), Positives = 270/303 (89%)

Query: 23  ESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSF 82
           +S + VY  FM+SH+CYD++PTSSKLVVFDT+LQVKKAFFALV NGVRAAPLW+SKKQSF
Sbjct: 14  DSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSF 73

Query: 83  VGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAV 142
           VGMLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV
Sbjct: 74  VGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAV 133

Query: 143 SSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202
            SLI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY 
Sbjct: 134 YSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYH 193

Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262
           NIA +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++V
Sbjct: 194 NIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITV 253

Query: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322
           T+ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL
Sbjct: 254 TQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQAL 313

Query: 323 VLT 325
           +LT
Sbjct: 314 ILT 316


>gi|33186925 AMP-activated protein kinase gamma2 subunit isoform a
           [Homo sapiens]
          Length = 569

 Score =  473 bits (1218), Expect = e-134
 Identities = 233/303 (76%), Positives = 270/303 (89%)

Query: 23  ESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSF 82
           +S + VY  FM+SH+CYD++PTSSKLVVFDT+LQVKKAFFALV NGVRAAPLW+SKKQSF
Sbjct: 255 DSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSF 314

Query: 83  VGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAV 142
           VGMLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV
Sbjct: 315 VGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAV 374

Query: 143 SSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202
            SLI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY 
Sbjct: 375 YSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYH 434

Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262
           NIA +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++V
Sbjct: 435 NIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITV 494

Query: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322
           T+ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL
Sbjct: 495 TQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQAL 554

Query: 323 VLT 325
           +LT
Sbjct: 555 ILT 557


>gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3
           subunit [Homo sapiens]
          Length = 489

 Score =  396 bits (1017), Expect = e-110
 Identities = 193/298 (64%), Positives = 246/298 (82%)

Query: 28  VYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLT 87
           +Y  FM+ H CYD + TSSKLV+FDT L++KKAFFALV NGVRAAPLWDSKKQSFVGMLT
Sbjct: 183 IYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLT 242

Query: 88  ITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIR 147
           ITDFI +LHRYY+S LVQIYE+E+HKIETWRE+YLQ  FKPLV ISPN SLF+AV +LI+
Sbjct: 243 ITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPLVSISPNDSLFEAVYTLIK 302

Query: 148 NKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMV 207
           N+IHRLPV+DP SGN L+ILTHKR+LKFL +F +  P+P F+ +++++L IGT+ ++A+V
Sbjct: 303 NRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVV 362

Query: 208 RTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQ 267
             T P+  AL IFV  RVSALPVV+E G+VV +YS+FDVI+LAA++TYN+LD+SV +AL+
Sbjct: 363 LETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALR 422

Query: 268 HRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLT 325
            R+   EGVL C  HE+L  +I+R+   +VHRLV+VDE   + G+VSLSDILQALVL+
Sbjct: 423 QRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLS 480


>gi|170763513 ATP/GTP binding protein 1 [Homo sapiens]
          Length = 1186

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 39/195 (20%), Positives = 82/195 (42%), Gaps = 17/195 (8%)

Query: 140 DAVSSLIRNKIHRLPVIDPESGN---TLYILTHKRILKFLKLFITEFPKPEFMSKSLEEL 196
           D +++L+++K +    +D        T+Y+  H+   +   + I +        KS+  +
Sbjct: 225 DTLAALLKSKTNARRAVDRGYVQVLLTIYVDWHRHDNRHRNMLIRKGILQSL--KSVTNI 282

Query: 197 QIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYN 256
           ++G  A I           A G+ + +  S LPV+   G V  +YS    ++   +++ +
Sbjct: 283 KLGRKAFID----------ANGMKILYNTSQLPVIPVTGPVAQLYSLPPEVDDVVDESDD 332

Query: 257 NLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLS 316
           N D+ V    ++ +   + + + + ++ +ET IN+L   +     + D          L 
Sbjct: 333 NDDIDV--EAENETENEDDLDQNFKNDDIETDINKLKPQQEPGRTIEDLKMYEHLFPELV 390

Query: 317 DILQALVLTGGEKKP 331
           D  Q   L   E KP
Sbjct: 391 DDFQDYDLISKEPKP 405


>gi|157388965 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


>gi|157388963 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


>gi|157388961 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


>gi|157388959 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


>gi|157388957 schlafen family member 11 [Homo sapiens]
          Length = 901

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


>gi|56119108 schlafen family member 13 [Homo sapiens]
          Length = 897

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 19/77 (24%), Positives = 34/77 (44%)

Query: 245 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVD 304
           +V+NL   + Y     S+ K  +   H   G  K  +   +   I  +   E HR++ V 
Sbjct: 572 EVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVC 631

Query: 305 ENDVVKGIVSLSDILQA 321
           EN  ++  +S  +I +A
Sbjct: 632 ENQPLRNFISDRNICRA 648


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,439,484
Number of Sequences: 37866
Number of extensions: 465269
Number of successful extensions: 996
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 981
Number of HSP's gapped (non-prelim): 13
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.