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Search of human proteins with 4505651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505651 phosphate cytidylyltransferase 2, ethanolamine [Homo
sapiens]
(389 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505651 phosphate cytidylyltransferase 2, ethanolamine [Homo ... 801 0.0
gi|253795516 choline phosphate cytidylyltransferase 1 beta isofo... 104 2e-22
gi|253795514 choline phosphate cytidylyltransferase 1 beta isofo... 104 2e-22
gi|21361202 choline phosphate cytidylyltransferase 1 beta isofor... 104 2e-22
gi|31543385 choline phosphate cytidylyltransferase 1 alpha [Homo... 103 3e-22
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 35 0.088
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 35 0.088
gi|188595687 gamma filamin isoform b [Homo sapiens] 33 0.57
gi|116805322 gamma filamin isoform a [Homo sapiens] 33 0.57
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 32 0.75
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 30 3.7
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 30 4.9
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 30 4.9
>gi|4505651 phosphate cytidylyltransferase 2, ethanolamine [Homo
sapiens]
Length = 389
Score = 801 bits (2070), Expect = 0.0
Identities = 389/389 (100%), Positives = 389/389 (100%)
Query: 1 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDE 60
MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDE
Sbjct: 1 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDE 60
Query: 61 EIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTV 120
EIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTV
Sbjct: 61 EIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTV 120
Query: 121 DGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKC 180
DGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKC
Sbjct: 121 DGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKC 180
Query: 181 PGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLA 240
PGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLA
Sbjct: 181 PGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLA 240
Query: 241 ERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHF 300
ERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHF
Sbjct: 241 ERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHF 300
Query: 301 KVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARN 360
KVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARN
Sbjct: 301 KVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARN 360
Query: 361 QKKEAKELAFLEAARQQAAQPLGERDGDF 389
QKKEAKELAFLEAARQQAAQPLGERDGDF
Sbjct: 361 QKKEAKELAFLEAARQQAAQPLGERDGDF 389
>gi|253795516 choline phosphate cytidylyltransferase 1 beta isoform
3 [Homo sapiens]
Length = 330
Score = 104 bits (259), Expect = 2e-22
Identities = 52/141 (36%), Positives = 85/141 (60%), Gaps = 2/141 (1%)
Query: 16 GPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAM--GDYLIVGVHTDEEIAKHKGPPVFTQ 73
G R VRV+ DG +D+ H GH+ L QA+ + YL+VGV +D+ K KG V +
Sbjct: 70 GTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNE 129
Query: 74 EERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAG 133
ERY+ ++ ++VDEV+ AP+ T E L+K+ DF H + + D Y+ +K+AG
Sbjct: 130 AERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAG 189
Query: 134 RYRECKRTQGVSTTDLVGRML 154
+ +RT+G+ST+D++ R++
Sbjct: 190 MFVPTQRTEGISTSDIITRIV 210
Score = 82.4 bits (202), Expect = 6e-16
Identities = 54/156 (34%), Positives = 79/156 (50%), Gaps = 7/156 (4%)
Query: 216 IYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSV 275
+Y G FDLFH GH L + L Y++ G+ D + +KG + +MN ER ++
Sbjct: 79 VYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKG--FTVMNEAERYEAL 136
Query: 276 LACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQI 334
CRYV EV+ AP+ +T E L K+D V H +I GSD Y+ K G+F
Sbjct: 137 RHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAH--DDIPYSSAGSDDVYKHIKEAGMFVPT 194
Query: 335 DSGSNLTTDLIVQRIITNRLEYEARNQKK--EAKEL 368
++T I+ RI+ + Y RN ++ AKEL
Sbjct: 195 QRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 230
>gi|253795514 choline phosphate cytidylyltransferase 1 beta isoform
2 [Homo sapiens]
Length = 351
Score = 104 bits (259), Expect = 2e-22
Identities = 52/141 (36%), Positives = 85/141 (60%), Gaps = 2/141 (1%)
Query: 16 GPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAM--GDYLIVGVHTDEEIAKHKGPPVFTQ 73
G R VRV+ DG +D+ H GH+ L QA+ + YL+VGV +D+ K KG V +
Sbjct: 52 GTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNE 111
Query: 74 EERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAG 133
ERY+ ++ ++VDEV+ AP+ T E L+K+ DF H + + D Y+ +K+AG
Sbjct: 112 AERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAG 171
Query: 134 RYRECKRTQGVSTTDLVGRML 154
+ +RT+G+ST+D++ R++
Sbjct: 172 MFVPTQRTEGISTSDIITRIV 192
Score = 82.4 bits (202), Expect = 6e-16
Identities = 54/156 (34%), Positives = 79/156 (50%), Gaps = 7/156 (4%)
Query: 216 IYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSV 275
+Y G FDLFH GH L + L Y++ G+ D + +KG + +MN ER ++
Sbjct: 61 VYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKG--FTVMNEAERYEAL 118
Query: 276 LACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQI 334
CRYV EV+ AP+ +T E L K+D V H +I GSD Y+ K G+F
Sbjct: 119 RHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAH--DDIPYSSAGSDDVYKHIKEAGMFVPT 176
Query: 335 DSGSNLTTDLIVQRIITNRLEYEARNQKK--EAKEL 368
++T I+ RI+ + Y RN ++ AKEL
Sbjct: 177 QRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 212
>gi|21361202 choline phosphate cytidylyltransferase 1 beta isoform 1
[Homo sapiens]
Length = 369
Score = 104 bits (259), Expect = 2e-22
Identities = 52/141 (36%), Positives = 85/141 (60%), Gaps = 2/141 (1%)
Query: 16 GPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAM--GDYLIVGVHTDEEIAKHKGPPVFTQ 73
G R VRV+ DG +D+ H GH+ L QA+ + YL+VGV +D+ K KG V +
Sbjct: 70 GTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNE 129
Query: 74 EERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAG 133
ERY+ ++ ++VDEV+ AP+ T E L+K+ DF H + + D Y+ +K+AG
Sbjct: 130 AERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAG 189
Query: 134 RYRECKRTQGVSTTDLVGRML 154
+ +RT+G+ST+D++ R++
Sbjct: 190 MFVPTQRTEGISTSDIITRIV 210
Score = 82.4 bits (202), Expect = 6e-16
Identities = 54/156 (34%), Positives = 79/156 (50%), Gaps = 7/156 (4%)
Query: 216 IYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSV 275
+Y G FDLFH GH L + L Y++ G+ D + +KG + +MN ER ++
Sbjct: 79 VYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKG--FTVMNEAERYEAL 136
Query: 276 LACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQI 334
CRYV EV+ AP+ +T E L K+D V H +I GSD Y+ K G+F
Sbjct: 137 RHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAH--DDIPYSSAGSDDVYKHIKEAGMFVPT 194
Query: 335 DSGSNLTTDLIVQRIITNRLEYEARNQKK--EAKEL 368
++T I+ RI+ + Y RN ++ AKEL
Sbjct: 195 QRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 230
>gi|31543385 choline phosphate cytidylyltransferase 1 alpha [Homo
sapiens]
Length = 367
Score = 103 bits (256), Expect = 3e-22
Identities = 54/136 (39%), Positives = 81/136 (59%), Gaps = 2/136 (1%)
Query: 21 RAVRVWCDGCYDMVHYGHSNQLRQARAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYK 78
R VRV+ DG +D+ H GH+ L QA+ + YLIVGV +DE KG V + ERY
Sbjct: 75 RPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYD 134
Query: 79 MVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYREC 138
VQ ++VDEVV AP+ T E L ++ DF H + + D Y+ +K+AG +
Sbjct: 135 AVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPT 194
Query: 139 KRTQGVSTTDLVGRML 154
+RT+G+ST+D++ R++
Sbjct: 195 QRTEGISTSDIITRIV 210
Score = 88.2 bits (217), Expect = 1e-17
Identities = 56/156 (35%), Positives = 83/156 (53%), Gaps = 7/156 (4%)
Query: 216 IYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSV 275
+Y G FDLFH GH L + L Y+I G+ D+ +++KG + +MN +ER +V
Sbjct: 79 VYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAV 136
Query: 276 LACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQI 334
CRYV EVV AP+ +T E L+ ++D V H +I GSD Y+ K G+F
Sbjct: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAH--DDIPYSSAGSDDVYKHIKEAGMFAPT 194
Query: 335 DSGSNLTTDLIVQRIITNRLEYEARNQKK--EAKEL 368
++T I+ RI+ + Y RN ++ AKEL
Sbjct: 195 QRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 230
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 35.4 bits (80), Expect = 0.088
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 15 PGPGGRRAVRVWCDGC-YDMVHYGHSNQLRQ--ARAMGDYLIVGVH-----TDEEIAKHK 66
PGPG A +V G + G + ++A + L+VGVH +E + KH
Sbjct: 2550 PGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHV 2609
Query: 67 GPPVFTQ----EERYKMVQAIKWVDEVVPAAPY 95
G +++ +++ + +KW DE +P +PY
Sbjct: 2610 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2642
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 35.4 bits (80), Expect = 0.088
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 15 PGPGGRRAVRVWCDGC-YDMVHYGHSNQLRQ--ARAMGDYLIVGVH-----TDEEIAKHK 66
PGPG A +V G + G + ++A + L+VGVH +E + KH
Sbjct: 2542 PGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHV 2601
Query: 67 GPPVFTQ----EERYKMVQAIKWVDEVVPAAPY 95
G +++ +++ + +KW DE +P +PY
Sbjct: 2602 GSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPY 2634
>gi|188595687 gamma filamin isoform b [Homo sapiens]
Length = 2692
Score = 32.7 bits (73), Expect = 0.57
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 9/60 (15%)
Query: 45 ARAMGDYLIVGVH-----TDEEIAKHKGPPVF----TQEERYKMVQAIKWVDEVVPAAPY 95
++A + ++VGVH +E KH G V+ T +E+ + +KW DE VP +P+
Sbjct: 2628 SKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPF 2687
>gi|116805322 gamma filamin isoform a [Homo sapiens]
Length = 2725
Score = 32.7 bits (73), Expect = 0.57
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 9/60 (15%)
Query: 45 ARAMGDYLIVGVH-----TDEEIAKHKGPPVF----TQEERYKMVQAIKWVDEVVPAAPY 95
++A + ++VGVH +E KH G V+ T +E+ + +KW DE VP +P+
Sbjct: 2661 SKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPF 2720
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 32.3 bits (72), Expect = 0.75
Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 9/64 (14%)
Query: 45 ARAMGDYLIVGVH-----TDEEIAKHKGPP----VFTQEERYKMVQAIKWVDEVVPAAPY 95
++A + L++GVH +E KH G + +ER V A+KW +E +P +P+
Sbjct: 2538 SKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPF 2597
Query: 96 VTTL 99
T+
Sbjct: 2598 HVTV 2601
>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo
sapiens]
Length = 1079
Score = 30.0 bits (66), Expect = 3.7
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 174 ADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIG---HV 230
+ SFG+ P G+ W S T +++ Q +G E G+ + GA + + H+
Sbjct: 71 SSSFGRWPKGQTMWAQTSTLTLTEEELGQSQAGGESGSGQLLDQENGAGESALVSVYVHL 130
Query: 231 DFLEK 235
DF +K
Sbjct: 131 DFPDK 135
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 29.6 bits (65), Expect = 4.9
Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 285 VIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDL 344
++G+P T+ ++ G + + D SD + +RR R I +GS L+
Sbjct: 1472 LVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESE 1531
Query: 345 IVQRIITNRLEYEARNQKKEAKE 367
+ + T+ L A + +E+KE
Sbjct: 1532 VEDSLATS-LSSSASSSSEESKE 1553
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 29.6 bits (65), Expect = 4.9
Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 285 VIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDL 344
++G+P T+ ++ G + + D SD + +RR R I +GS L+
Sbjct: 1472 LVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESE 1531
Query: 345 IVQRIITNRLEYEARNQKKEAKE 367
+ + T+ L A + +E+KE
Sbjct: 1532 VEDSLATS-LSSSASSSSEESKE 1553
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,445,484
Number of Sequences: 37866
Number of extensions: 678011
Number of successful extensions: 2007
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1975
Number of HSP's gapped (non-prelim): 20
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.