Search of human proteins with 4505469

Search of human proteins with 4505469

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo
sapiens]
         (257 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens]    523   e-149
gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens]      523   e-149
gi|70995319 nerve growth factor, beta polypeptide precursor [Hom...   183   1e-46
gi|219842314 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842312 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842309 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842306 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842303 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842300 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842298 brain-derived neurotrophic factor isoform e [Homo s...   172   3e-43
gi|219842296 brain-derived neurotrophic factor isoform d preprop...   172   3e-43
gi|219842294 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842292 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842290 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|219842288 brain-derived neurotrophic factor isoform a preprop...   172   3e-43
gi|25306264 brain-derived neurotrophic factor isoform a prepropr...   172   3e-43
gi|25306261 brain-derived neurotrophic factor isoform c prepropr...   172   3e-43
gi|25306267 brain-derived neurotrophic factor isoform a prepropr...   172   3e-43
gi|25306257 brain-derived neurotrophic factor isoform a prepropr...   172   3e-43
gi|25306253 brain-derived neurotrophic factor isoform a prepropr...   172   3e-43
gi|25306235 brain-derived neurotrophic factor isoform b prepropr...   172   3e-43
gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]                167   8e-42
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            32   0.71 
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    32   0.71 
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    32   0.71 
gi|31581524 cordon-bleu homolog [Homo sapiens]                         30   2.1  
gi|46276868 hypothetical protein LOC9710 [Homo sapiens]                30   2.7  
gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens]          29   3.5  
gi|40789270 zinc finger protein 573 [Homo sapiens]                     29   3.5  
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13...    28   6.0  

>gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens]
          Length = 270

 Score =  523 bits (1346), Expect = e-149
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 60
           MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ
Sbjct: 14  MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 73

Query: 61  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 120
           STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM
Sbjct: 74  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 133

Query: 121 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 180
           EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK
Sbjct: 134 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 193

Query: 181 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 240
           TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI
Sbjct: 194 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 253

Query: 241 RIDTSCVCALSRKIGRT 257
           RIDTSCVCALSRKIGRT
Sbjct: 254 RIDTSCVCALSRKIGRT 270


>gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens]
          Length = 257

 Score =  523 bits (1346), Expect = e-149
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 60
           MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ
Sbjct: 1   MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 60

Query: 61  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 120
           STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM
Sbjct: 61  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 120

Query: 121 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 180
           EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK
Sbjct: 121 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 180

Query: 181 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 240
           TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI
Sbjct: 181 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 240

Query: 241 RIDTSCVCALSRKIGRT 257
           RIDTSCVCALSRKIGRT
Sbjct: 241 RIDTSCVCALSRKIGRT 257


>gi|70995319 nerve growth factor, beta polypeptide precursor [Homo
           sapiens]
          Length = 241

 Score =  183 bits (464), Expect = 1e-46
 Identities = 110/258 (42%), Positives = 148/258 (57%), Gaps = 21/258 (8%)

Query: 1   MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 60
           MS+LFY +  A+L GIQ     + ++P          + QA   K         ++ +  
Sbjct: 1   MSMLFYTLITAFLIGIQAEPHSESNVPAGHT------IPQAHWTK---------LQHSLD 45

Query: 61  STLPKAEAPREPERGGPAKSAFQPV-IAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYL 119
           + L +A +   P     A+ A Q   I +D  L ++ RR  SPRVL S   P E      
Sbjct: 46  TALRRARSA--PAAAIAARVAGQTRNITVDPRLFKK-RRLRSPRVLFSTQPPREAADTQD 102

Query: 120 MEDYVGSPVVANRTSRRKRYAEHKS-HRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGE 178
           ++  VG     NRT R KR + H   HRGE+SVCDS S+WV DK++A DI+G +V VLGE
Sbjct: 103 LDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGE 162

Query: 179 IKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWR 238
           +   NS  KQYF+ET+C++  PV +GCRGID KHWNS C T+ T+V+ALT +  K   WR
Sbjct: 163 VNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMD-GKQAAWR 221

Query: 239 WIRIDTSCVCALSRKIGR 256
           +IRIDT+CVC LSRK  R
Sbjct: 222 FIRIDTACVCVLSRKAVR 239


>gi|219842314 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842312 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842309 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842306 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842303 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842300 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842298 brain-derived neurotrophic factor isoform e [Homo
           sapiens]
          Length = 329

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 175 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 233

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 234 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 293

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 294 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 329


>gi|219842296 brain-derived neurotrophic factor isoform d
           preproprotein [Homo sapiens]
          Length = 276

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 122 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 180

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 181 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 240

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 241 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 276


>gi|219842294 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842292 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842290 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842288 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306264 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306261 brain-derived neurotrophic factor isoform c
           preproprotein [Homo sapiens]
          Length = 262

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 108 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 166

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 167 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 226

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 227 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 262


>gi|25306267 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306257 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306253 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306235 brain-derived neurotrophic factor isoform b
           preproprotein [Homo sapiens]
          Length = 255

 Score =  172 bits (435), Expect = 3e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 103 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 160
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 101 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 159

Query: 161 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 160 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 219

Query: 221 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 256
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 220 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 255


>gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]
          Length = 210

 Score =  167 bits (423), Expect = 8e-42
 Identities = 91/201 (45%), Positives = 120/201 (59%), Gaps = 22/201 (10%)

Query: 69  PREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLME-----DY 123
           P  P    P  S   P +A + +LL       SPRV+LS   P  PP L+L+E     + 
Sbjct: 18  PSVPIESQPPPSTLPPFLAPEWDLL-------SPRVVLSRGAPAGPPLLFLLEAGAFRES 70

Query: 124 VGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKT-G 182
            G+P  ANR+ R        S RGE +VCD+ S WVTD+ +A+D+RG +V VLGE+   G
Sbjct: 71  AGAP--ANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAG 128

Query: 183 NSPVKQYFYETRCKEARPVKNG-------CRGIDDKHWNSQCKTSQTYVRALTSENNKLV 235
            SP++QYF+ETRCK     + G       CRG+D +HW S+CK  Q+YVRALT++    V
Sbjct: 129 GSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRV 188

Query: 236 GWRWIRIDTSCVCALSRKIGR 256
           GWRWIRIDT+CVC L  + GR
Sbjct: 189 GWRWIRIDTACVCTLLSRTGR 209


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 31.6 bits (70), Expect = 0.71
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 7/116 (6%)

Query: 78  AKSAFQPVIAMDTELLRQQR---RYNSPRVLLSDSTPLEPPPLYLMEDYVGSPVVANRTS 134
           +K   + ++  + +LLR  R   R +S + + S S P   PP    ED  GS    + + 
Sbjct: 633 SKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPP----EDPFGSVPFISHSG 688

Query: 135 RRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYF 190
             ++ AEH S   E    +      T  +S     G + +V G+++ GN   +  F
Sbjct: 689 SPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDF 744


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
           sapiens]
          Length = 3667

 Score = 31.6 bits (70), Expect = 0.71
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 113 EPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGE-YSVCDSESLWVTDKSSAIDIRGH 171
           EPP ++L    +  P+++N+   R  +    +HR   +S     S  +T  +S  ++  H
Sbjct: 261 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH 320

Query: 172 QVTVLGEIKTGNSP 185
             T  G I   ++P
Sbjct: 321 NRTTTGAIAVASTP 334


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo
           sapiens]
          Length = 3707

 Score = 31.6 bits (70), Expect = 0.71
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 113 EPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGE-YSVCDSESLWVTDKSSAIDIRGH 171
           EPP ++L    +  P+++N+   R  +    +HR   +S     S  +T  +S  ++  H
Sbjct: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH 360

Query: 172 QVTVLGEIKTGNSP 185
             T  G I   ++P
Sbjct: 361 NRTTTGAIAVASTP 374


>gi|31581524 cordon-bleu homolog [Homo sapiens]
          Length = 1261

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 13/78 (16%)

Query: 60  QSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYL 119
           +S + K  AP  P  G P +      +++ +++  Q+++  +P    +   P  PPP   
Sbjct: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAP----APPPPQPPPP--- 346

Query: 120 MEDYVGSPVVANRTSRRK 137
                 SP++ NRT  ++
Sbjct: 347 ------SPLIPNRTEDKE 358


>gi|46276868 hypothetical protein LOC9710 [Homo sapiens]
          Length = 1070

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 48  LSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQR-RYNSPRVLL 106
           +++Q     +  Q +LP    PR P+ G       QP +A   +  +QQ+ +    + LL
Sbjct: 679 VTEQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLL 738

Query: 107 SDSTPLEPPP 116
               P +PPP
Sbjct: 739 QPIGPQQPPP 748


>gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens]
          Length = 190

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 14  RGIQGNNMDQRSLPEDSLNSLIIKLIQA------DILKNKLSKQMVDVKENYQSTL-PKA 66
           R  Q    +  S PE SL +  I+L++       D+    L   +VD+  N    +  K 
Sbjct: 14  RQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVDLTHNDSVVIVDKR 73

Query: 67  EAPREPERGGPAKSAFQPVIAMDTELLRQQR 97
             PR   R  P   A   +++ D ELL + R
Sbjct: 74  RRPRRNARRLPQDHADSSMVSSDDELLSRDR 104


>gi|40789270 zinc finger protein 573 [Homo sapiens]
          Length = 607

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 30/112 (26%)

Query: 134 SRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYET 193
           SRR    EH    G++     E  ++ +K      RGHQ+TV   + TG  P     YE 
Sbjct: 226 SRRSNLVEH----GQFHT--DEKPYICEKCGKAFRRGHQLTVHQRVHTGKKP-----YE- 273

Query: 194 RCKEA-------------RPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENN 232
            CKE              + +  G +  + K    +CK + T  R LT   N
Sbjct: 274 -CKECGKGYTTASYFLLHQRIHKGGKPYECK----ECKKTFTLYRNLTRHQN 320


>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
            [Homo sapiens]
          Length = 5058

 Score = 28.5 bits (62), Expect = 6.0
 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 163  SSAIDIRGH-QVTVLGEIKTGNSPV-KQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 220
            S+A+ + G   + +L E  +G  P  K+Y ++T  KE   V+ GC  +   H   +C+  
Sbjct: 4866 STALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKE---VREGCAAVLTSHSMEECEAL 4922

Query: 221  QTYVRALTSENNKLVG 236
             T +  + + + K +G
Sbjct: 4923 CTRLAIMVNGSFKCLG 4938


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,234,612
Number of Sequences: 37866
Number of extensions: 464994
Number of successful extensions: 1394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1326
Number of HSP's gapped (non-prelim): 44
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.