Guide to the Human Genome
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Search of human proteins with 4505235

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505235 mannose-6- phosphate isomerase [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505235 mannose-6- phosphate isomerase [Homo sapiens]              848   0.0  
gi|48717285 hypothetical protein LOC389763 [Homo sapiens]              32   1.1  
gi|221219015 olfactory receptor, family 52, subfamily L, member ...    32   1.1  
gi|155029539 alpha accessory factor 132 [Homo sapiens]                 31   1.9  
gi|166795280 forkhead box N4 [Homo sapiens]                            30   3.2  
gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens]        30   4.1  
gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens]      30   4.1  
gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   7.1  
gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   7.1  
gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   7.1  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    29   7.1  
gi|46240864 sperm associated antigen 17 [Homo sapiens]                 29   9.2  
gi|55770834 centromere protein F [Homo sapiens]                        29   9.2  
gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]          29   9.2  

>gi|4505235 mannose-6- phosphate isomerase [Homo sapiens]
          Length = 423

 Score =  848 bits (2191), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 60
           MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
Sbjct: 1   MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK 60

Query: 61  ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 120
           ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
Sbjct: 61  ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK 120

Query: 121 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 180
           LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
Sbjct: 121 LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK 180

Query: 181 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 240
           QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
Sbjct: 181 QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ 240

Query: 241 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 300
           LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
Sbjct: 241 LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP 300

Query: 301 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 360
           KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
Sbjct: 301 KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK 360

Query: 361 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 420
           VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
Sbjct: 361 VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC 420

Query: 421 CLL 423
           CLL
Sbjct: 421 CLL 423


>gi|48717285 hypothetical protein LOC389763 [Homo sapiens]
          Length = 1576

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 5/70 (7%)

Query: 124  QAPQHYP----DANHKPEMAIALTPFQGL-CGFRPVEEIVTFLKKVPEFQFLIGDEAATH 178
            Q P  +P     A H PE+ +   P QG  C +R     VT  K   +    +G    T 
Sbjct: 1429 QEPLSFPVGLGKAQHNPEVHVRAEPVQGCPCNYRAPSCKVTRTKSCSQQAIFVGQNYPTR 1488

Query: 179  LKQTMSHDSQ 188
            ++Q +  D Q
Sbjct: 1489 IRQIIDKDRQ 1498


>gi|221219015 olfactory receptor, family 52, subfamily L, member 1
           [Homo sapiens]
          Length = 329

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 10/65 (15%)

Query: 245 YPGDIGCFAIYFL--NLLTLKP-----GEAMFLEANV-PHAYLKGDCVECMACSDNTVRA 296
           +PG IGC  +  L   LL L P     G+ +F +A +  HAY +   V  +ACS+ TV  
Sbjct: 155 HPGVIGCIGMVVLVRGLLLLIPFPILLGKLIFCQATIIGHAYCEHMAVVKLACSETTVNR 214

Query: 297 --GLT 299
             GLT
Sbjct: 215 AYGLT 219


>gi|155029539 alpha accessory factor 132 [Homo sapiens]
          Length = 1217

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)

Query: 329 SQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQ 374
           S  + +L ++D PVP F +  T  PG VT   VL  +SAS LL ++
Sbjct: 173 SSGEGHLELWDAPVPVFPL--TISPGPVTPIPVLYPESASCLLRLR 216


>gi|166795280 forkhead box N4 [Homo sapiens]
          Length = 517

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 16/110 (14%)

Query: 110 QAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQF 169
           Q H     +++LH   P+HYP   +     IA+       G  PV EI +F+K+     F
Sbjct: 175 QPHVAVHSSQELH---PKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKE----HF 227

Query: 170 LIGDEAATHLKQTMSHDSQAVASSLQSCF----SHLMKSEKKVVVEQLNL 215
                A    K ++ H+      SL  CF    + +  S +K  +  LNL
Sbjct: 228 PYFKTAPDGWKNSVRHN-----LSLNKCFEKVENKMSGSSRKGCLWALNL 272


>gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 18/156 (11%)

Query: 69  KTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQH 128
           K L +    N+ S+    K   +  L  L   L V+  L  +    KEL E+L  + P  
Sbjct: 214 KRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIK 273

Query: 129 YPDANHKPEMAIALTPFQGLCG--FRPVEEIVTFLKKVPEFQFLIGDEAATHLKQ----- 181
                 K EM     P   + G  +  +   V + KK    + L+ ++A  HLKQ     
Sbjct: 274 EVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKK----EELVAEQALKHLKQYAPLL 329

Query: 182 -TMSHDSQAVASSLQS----CFS--HLMKSEKKVVV 210
              S   Q+    LQ     C+   H MK+ +K+VV
Sbjct: 330 AVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVV 365


>gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 18/156 (11%)

Query: 69  KTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQH 128
           K L +    N+ S+    K   +  L  L   L V+  L  +    KEL E+L  + P  
Sbjct: 214 KRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIK 273

Query: 129 YPDANHKPEMAIALTPFQGLCG--FRPVEEIVTFLKKVPEFQFLIGDEAATHLKQ----- 181
                 K EM     P   + G  +  +   V + KK    + L+ ++A  HLKQ     
Sbjct: 274 EVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKK----EELVAEQALKHLKQYAPLL 329

Query: 182 -TMSHDSQAVASSLQS----CFS--HLMKSEKKVVV 210
              S   Q+    LQ     C+   H MK+ +K+VV
Sbjct: 330 AVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVV 365


>gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 130 PDANHKPEMAIALTPFQGLCGFRPVEE-IVTFLKKVPEFQFLIGDEAAT 177
           P    KP  A+A  P   +CG RP++    + L K P     +GD+  T
Sbjct: 402 PHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFT 450


>gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 130 PDANHKPEMAIALTPFQGLCGFRPVEE-IVTFLKKVPEFQFLIGDEAAT 177
           P    KP  A+A  P   +CG RP++    + L K P     +GD+  T
Sbjct: 402 PHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFT 450


>gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 130 PDANHKPEMAIALTPFQGLCGFRPVEE-IVTFLKKVPEFQFLIGDEAAT 177
           P    KP  A+A  P   +CG RP++    + L K P     +GD+  T
Sbjct: 402 PHGGGKPSQALAAGPTVSMCGMRPLQGWSRSLLPKWPPATLWLGDDLFT 450


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 10/163 (6%)

Query: 69   KTLSQWIAENQDSL--GSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAP 126
            K L+QWIAE Q+ L    + K         L K  S++  +       K + EK      
Sbjct: 3811 KALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALL- 3869

Query: 127  QHYPDANHKPEMAIALTPFQGLC--GFRPVEEIVTFLKKVPEFQF----LIGDEAATHLK 180
            +   D   K ++    + +Q LC  G   +EEI  F  ++   Q     LIG + A HL+
Sbjct: 3870 ELVQDVTLKDKIDQLQSDYQDLCSIGKAMMEEIAGFEDRLNNLQMKGDTLIG-QCADHLQ 3928

Query: 181  QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQ 223
              +  +  A     +  +S +  + +++     + L K +S+Q
Sbjct: 3929 AKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQ 3971


>gi|46240864 sperm associated antigen 17 [Homo sapiens]
          Length = 2223

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 69   KTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKEL-AEKLHLQAPQ 127
            K L  +  +N+D+  + V+DT + NL F    +S +   S+ + P  E+ A+K    A  
Sbjct: 1932 KKLPSFTKKNEDANETAVQDTSDLNLDFKPHKVSEQKSSSVPSLPKPEISADKKDFTAQN 1991

Query: 128  HYPDANHKPEMAIALTP 144
               +    PE A +  P
Sbjct: 1992 QTENLTKSPEEAESYEP 2008


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 18/51 (35%), Positives = 26/51 (50%)

Query: 77   ENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQ 127
            E+  +L  +VK+T N NL  L  +   +  +    +  KEL  KLHLQ  Q
Sbjct: 1767 EDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQ 1817


>gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]
          Length = 581

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 118 AEKLHLQAPQHYPDANHKPEMAIALTPFQGL--CG--FRPV--EEIVTFLKKVPEFQFLI 171
           AE LH Q PQH     ++P+ +      + L  CG  + P+  E+    LK  P+  FL+
Sbjct: 365 AESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLV 424

Query: 172 GDEAATHLKQTMSHDSQAV 190
            D +      ++S  SQ +
Sbjct: 425 RDSSDPRYILSLSFRSQGI 443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,355,064
Number of Sequences: 37866
Number of extensions: 720219
Number of successful extensions: 1692
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 18
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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