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Search of human proteins with 13128968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
(211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 434 e-122
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 196 9e-51
gi|51491914 dual specificity phosphatase and pro isomerase domai... 175 3e-44
gi|56117822 testis and skeletal muscle-specific dual specificity... 167 6e-42
gi|56237018 testis and skeletal muscle-specific dual specificity... 167 8e-42
gi|56117820 testis and skeletal muscle-specific dual specificity... 167 8e-42
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 147 5e-36
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 124 4e-29
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 94 1e-19
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 91 7e-19
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 89 4e-18
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 87 8e-18
gi|239582767 slingshot homolog 3 [Homo sapiens] 84 9e-17
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 84 9e-17
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 84 9e-17
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 83 2e-16
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 82 3e-16
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 80 1e-15
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 78 5e-15
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 75 4e-14
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 75 4e-14
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 75 4e-14
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 75 4e-14
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 74 7e-14
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 73 2e-13
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 72 3e-13
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 72 3e-13
gi|37674210 slingshot 2 [Homo sapiens] 71 6e-13
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 71 8e-13
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 70 1e-12
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 434 bits (1115), Expect = e-122
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACN 60
MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACN
Sbjct: 1 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACN 60
Query: 61 HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD 120
HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD
Sbjct: 61 HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD 120
Query: 121 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK 180
SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK
Sbjct: 121 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK 180
Query: 181 KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA 211
KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
Sbjct: 181 KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA 211
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 196 bits (499), Expect = 9e-51
Identities = 99/168 (58%), Positives = 124/168 (73%), Gaps = 3/168 (1%)
Query: 41 PFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRW- 99
P ++ ELE LL GK++C+ DEVWP L++GD ANNR EL +LGITHVLNA+H
Sbjct: 17 PCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLY 76
Query: 100 -RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSR 158
+G P+ Y G + YLGV AHD P FD+S +F +AADFIHRAL+ PG K+LVHC VGVSR
Sbjct: 77 CQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSR 135
Query: 159 SATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLR 206
SATLVLAYLML+ L+L +A+ V+ HR + PNRGFL QL LD++LR
Sbjct: 136 SATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQLR 183
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 175 bits (443), Expect = 3e-44
Identities = 89/164 (54%), Positives = 115/164 (70%), Gaps = 2/164 (1%)
Query: 46 FELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT--P 103
FELERL + G H +EVWP LY+GD+ A +R L++ G THVLNA+H RW P
Sbjct: 39 FELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGP 98
Query: 104 EAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLV 163
+ Y + I+Y GVEA D P FD+S+ F AA FI RALS KILVHC +G SRSATLV
Sbjct: 99 DYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLV 158
Query: 164 LAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQ 207
LAYLM++ +TLV+AI++V +R ++PNRGFL+QL LD++L Q
Sbjct: 159 LAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQ 202
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 167 bits (423), Expect = 6e-42
Identities = 96/202 (47%), Positives = 131/202 (64%), Gaps = 8/202 (3%)
Query: 8 WASMTF-MARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTAC-NHADEV 65
WA + M + R P + G ++ P Q P L L+RLL+ + A NH DEV
Sbjct: 87 WARYSHRMDSLQKQDLRRP-KIHGAVQASP-YQPPTLA--SLQRLLWVRQAATLNHIDEV 142
Query: 66 WPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA--YEGLGIRYLGVEAHDSPA 123
WP L+LGD A ++ +L +LGITHV+NA+ +++ A Y G+ + Y G+EA D+P
Sbjct: 143 WPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPF 202
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
FD+S++F A +I ALS P G++LVHCA+GVSRSATLVLA+LM+ ++TLVEAI+ V+
Sbjct: 203 FDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQ 262
Query: 184 DHRGIIPNRGFLRQLLALDRRL 205
HR I PN GFLRQL LD RL
Sbjct: 263 AHRNICPNSGFLRQLQVLDNRL 284
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 167 bits (422), Expect = 8e-42
Identities = 86/161 (53%), Positives = 116/161 (72%), Gaps = 3/161 (1%)
Query: 48 LERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA- 105
L+RLL+ + A NH DEVWP L+LGD A ++ +L +LGITHV+NA+ +++ A
Sbjct: 31 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK 90
Query: 106 -YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVL 164
Y G+ + Y G+EA D+P FD+S++F A +I ALS P G++LVHCA+GVSRSATLVL
Sbjct: 91 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL 150
Query: 165 AYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205
A+LM+ ++TLVEAI+ V+ HR I PN GFLRQL LD RL
Sbjct: 151 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 191
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 167 bits (422), Expect = 8e-42
Identities = 86/161 (53%), Positives = 116/161 (72%), Gaps = 3/161 (1%)
Query: 48 LERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA- 105
L+RLL+ + A NH DEVWP L+LGD A ++ +L +LGITHV+NA+ +++ A
Sbjct: 81 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK 140
Query: 106 -YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVL 164
Y G+ + Y G+EA D+P FD+S++F A +I ALS P G++LVHCA+GVSRSATLVL
Sbjct: 141 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL 200
Query: 165 AYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205
A+LM+ ++TLVEAI+ V+ HR I PN GFLRQL LD RL
Sbjct: 201 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 241
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/55 (41%), Positives = 35/55 (63%)
Query: 41 PFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNAS 95
P ++ ELE LL GK++C+ DEVWP L++GD + +++LRR I + AS
Sbjct: 17 PCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRRPKIHGAVQAS 71
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 147 bits (372), Expect = 5e-36
Identities = 76/169 (44%), Positives = 111/169 (65%), Gaps = 3/169 (1%)
Query: 45 VFELERLLYTGKTAC--NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT 102
V +L+R L + N DEVWP +++ ++ +A N+ L+RLGITH+LNA+H T
Sbjct: 115 VLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYT 174
Query: 103 -PEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSAT 161
PE Y GL I+YLGVE D P D+S HF+ A++F+ AL GK+LV +G+SRSA
Sbjct: 175 GPEFYTGLEIQYLGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAV 234
Query: 162 LVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLE 210
LV+AYLM++H++ ++EA+ V+ R I PN GFL+QL L+ +L + E
Sbjct: 235 LVVAYLMIFHNMAILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEERE 283
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 124 bits (312), Expect = 4e-29
Identities = 72/171 (42%), Positives = 106/171 (61%), Gaps = 8/171 (4%)
Query: 43 LNVFELERLLYTGKTACN----HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSR 98
L+V +L LL G + +EV P +Y+G+ +A + +L++LGITHVLNA+ R
Sbjct: 7 LSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGR 66
Query: 99 W----RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAV 154
Y+ GI YLG++A+D+ F++S +F+ AADFI +AL+Q G++LVHC
Sbjct: 67 SFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCRE 126
Query: 155 GVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205
G SRS TLV+AYLM+ + + A+ V+ +R I PN GFL QL L+ RL
Sbjct: 127 GYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRL 177
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 93.6 bits (231), Expect = 1e-19
Identities = 59/143 (41%), Positives = 85/143 (59%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
++ L+LG +A+NR L+ GIT ++NA+ +E Y+ V D P
Sbjct: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFE-----YVKVPLADMPH 83
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
+ ++F T AD IH ++S+ G LVHCA GVSRSATL +AYLM +H++ L+EA VK
Sbjct: 84 APIGLYFDTVADKIH-SVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R +I PN GF RQL+ +R+L
Sbjct: 143 ARRPVIRPNVGFWRQLIDYERQL 165
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 90.9 bits (224), Expect = 7e-19
Identities = 58/143 (40%), Positives = 81/143 (56%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
E+ P L+LG +++ + L+ GIT VLN S S P +EGL RY + D+
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSAS----CPNHFEGL-FRYKSIPVEDNQM 229
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
++S FQ A FI + GG++LVHC G+SRSAT+ LAYLM + L EA VK
Sbjct: 230 VEISAWFQEAIGFIDW-VKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVK 288
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
RG+I PN F+ QLL + ++
Sbjct: 289 QRRGVISPNFSFMGQLLQFETQV 311
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 88.6 bits (218), Expect = 4e-18
Identities = 58/143 (40%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
E+ P LYLG A+ L L IT +LN S R T EA + Y + DS
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVS----RRTSEAC-ATHLHYKWIPVEDSHT 235
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
D+S HFQ A DFI + + GGK+LVHC G+SRS T+ +AYLM L EA +K
Sbjct: 236 ADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIK 294
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R ++ PN GF+ QLL + +
Sbjct: 295 QRRSMVSPNFGFMGQLLQYESEI 317
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 87.4 bits (215), Expect = 8e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
E+ P LYLG A+ + L LGIT ++N S + P +EG +Y + D+
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSAN----CPNHFEG-HYQYKSIPVEDNHK 230
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
D+S F A DFI ++ GG++ VHC G+SRSAT+ LAYLM + + L EA + VK
Sbjct: 231 ADISSWFNEAIDFID-SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVK 289
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R II PN F+ QLL + ++
Sbjct: 290 QRRSIISPNFSFMGQLLQFESQV 312
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 84.0 bits (206), Expect = 9e-17
Identities = 54/140 (38%), Positives = 77/140 (55%), Gaps = 7/140 (5%)
Query: 60 NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAH 119
+ A ++P LYLG + A N EL+R +TH+LN + PE + Y V
Sbjct: 327 DRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFT-----YHNVRLW 381
Query: 120 DSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAI 179
D + + H++ FI A +Q G +LVHC +GVSRSA VLAY M + +L +A+
Sbjct: 382 DEESAQLLPHWKETHRFIEAARAQ-GTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQAL 440
Query: 180 KKVKDHRGII-PNRGFLRQL 198
+ V++ R I PN GFLRQL
Sbjct: 441 RHVQELRPIARPNPGFLRQL 460
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 84.0 bits (206), Expect = 9e-17
Identities = 57/143 (39%), Positives = 78/143 (54%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
E+ P LYLG A R L LGIT +LN S P +EG +Y + D+
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSD----CPNHFEG-HYQYKCIPVEDNHK 252
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
D+S F A ++I A+ G++LVHC G+SRSAT+ LAYLM+ + L EA + VK
Sbjct: 253 ADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 311
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R II PN F+ QLL + ++
Sbjct: 312 QRRSIISPNFSFMGQLLQFESQV 334
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 84.0 bits (206), Expect = 9e-17
Identities = 57/143 (39%), Positives = 78/143 (54%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
E+ P LYLG A R L LGIT +LN S P +EG +Y + D+
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLNVSSD----CPNHFEG-HYQYKCIPVEDNHK 161
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
D+S F A ++I A+ G++LVHC G+SRSAT+ LAYLM+ + L EA + VK
Sbjct: 162 ADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 220
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R II PN F+ QLL + ++
Sbjct: 221 QRRSIISPNFSFMGQLLQFESQV 243
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 82.8 bits (203), Expect = 2e-16
Identities = 52/145 (35%), Positives = 80/145 (55%), Gaps = 8/145 (5%)
Query: 60 NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAH 119
N +++ PGLY+G+ A + +L + +TH+L+ H R E G++YL + A
Sbjct: 3 NGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSV-HDSARPMLE-----GVKYLCIPAA 56
Query: 120 DSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAI 179
DSP+ +++ HF+ + FIH + G LVHC GVSRS TLV+AY+M +A+
Sbjct: 57 DSPSQNLTRHFKESIKFIHECRLR-GESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDAL 115
Query: 180 KKVKDHRGII-PNRGFLRQLLALDR 203
V+ R PN GF RQL ++
Sbjct: 116 HTVRAGRSCANPNVGFQRQLQEFEK 140
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 82.4 bits (202), Expect = 3e-16
Identities = 57/145 (39%), Positives = 79/145 (54%), Gaps = 7/145 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLG-IRYLGVEAHDSP 122
++ P LYLG + N L +LGI ++LN + + P +E G Y + D
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPN----LPNFFEKNGDFHYKQIPISDHW 261
Query: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
+ ++S F A +FI ALSQ G +LVHC GVSRS T+ +AYLM HL+L +A V
Sbjct: 262 SQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
Query: 183 KDHR-GIIPNRGFLRQLLALDRRLR 206
K + I PN F+ QLL +R LR
Sbjct: 321 KRKKSNISPNFNFMGQLLDFERSLR 345
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 80.5 bits (197), Expect = 1e-15
Identities = 54/146 (36%), Positives = 81/146 (55%), Gaps = 5/146 (3%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
+ P L+LG++ A + ++RL I +V+N + YE Y + A DS
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHL---PLYHYEKGLFNYKRLPATDSNKQ 381
Query: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
++ +F+ A +FI A Q G +L+HC GVSRSAT+V+AYLM + +T+ +A K VK
Sbjct: 382 NLRQYFEEAFEFIEEA-HQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKG 440
Query: 185 HRGII-PNRGFLRQLLALDRRLRQGL 209
R II PN F+ QLL + L G+
Sbjct: 441 KRPIISPNLNFMGQLLEFEEDLNNGV 466
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 78.2 bits (191), Expect = 5e-15
Identities = 56/143 (39%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
++ LY+ + ANN+ L IT V+N S YE I+Y+ V DSP
Sbjct: 22 QITKSLYISNGVAANNKLMLSSNQITMVINVSVEV---VNTLYED--IQYMQVPVADSPN 76
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
+ F AD IH ++ G+ L+HCA GVSRSA L LAYLM YH ++L++A K
Sbjct: 77 SRLCDFFDPIADHIH-SVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTK 135
Query: 184 DHRGII-PNRGFLRQLLALDRRL 205
R II PN GF QL+ + +L
Sbjct: 136 SCRPIIRPNSGFWEQLIHYEFQL 158
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 75.1 bits (183), Expect = 4e-14
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 7/135 (5%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
++ LYLG + A+N EL+ G+ ++LN + R + GL Y + +D
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVT----REIDNFFPGL-FAYHNIRVYDEETT 366
Query: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
D+ H+ A FI++A + K LVHC +GVSRSA+ V+AY M L +A VK
Sbjct: 367 DLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQ 425
Query: 185 HRGII-PNRGFLRQL 198
R I PN GF+RQL
Sbjct: 426 KRSITRPNAGFMRQL 440
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 75.1 bits (183), Expect = 4e-14
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 7/135 (5%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
++ LYLG + A+N EL+ G+ ++LN + R + GL Y + +D
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVT----REIDNFFPGL-FAYHNIRVYDEETT 377
Query: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
D+ H+ A FI++A + K LVHC +GVSRSA+ V+AY M L +A VK
Sbjct: 378 DLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQ 436
Query: 185 HRGII-PNRGFLRQL 198
R I PN GF+RQL
Sbjct: 437 KRSITRPNAGFMRQL 451
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 75.1 bits (183), Expect = 4e-14
Identities = 50/135 (37%), Positives = 72/135 (53%), Gaps = 7/135 (5%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
++ LYLG + A+N EL+ G+ ++LN + R + GL Y + +D
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVT----REIDNFFPGL-FAYHNIRVYDEETT 366
Query: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
D+ H+ A FI++A + K LVHC +GVSRSA+ V+AY M L +A VK
Sbjct: 367 DLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQ 425
Query: 185 HRGII-PNRGFLRQL 198
R I PN GF+RQL
Sbjct: 426 KRSITRPNAGFMRQL 440
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 75.1 bits (183), Expect = 4e-14
Identities = 52/145 (35%), Positives = 83/145 (57%), Gaps = 10/145 (6%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT--PEAYEGLGIRYLGVEAHDSP 122
+ P LYLG Q N+ +++ GI +VLNAS++ + PE++ +L V +DS
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH------FLRVPVNDSF 215
Query: 123 AFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKV 182
+ + DFI +A + G +LVHC G+SRSAT+ +AY+M ++L EA + V
Sbjct: 216 CEKILPWLDKSVDFIEKAKAS-NGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFV 274
Query: 183 KDHRGII-PNRGFLRQLLALDRRLR 206
K+ R I PN FL QLL +++++
Sbjct: 275 KEKRPTISPNFNFLGQLLDYEKKIK 299
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 74.3 bits (181), Expect = 7e-14
Identities = 55/156 (35%), Positives = 79/156 (50%), Gaps = 12/156 (7%)
Query: 60 NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAH 119
N +V PGLYLG+ A + +L R ITH+++ S + I YL +
Sbjct: 3 NGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQD------ITYLRIPVA 56
Query: 120 DSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAI 179
D+P + HF+ +FIH GG LVHC G+SRS T+V AY+M L + +
Sbjct: 57 DTPEVPIKKHFKECINFIH-CCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVL 115
Query: 180 KKVKDHRGII-PNRGFLRQL----LALDRRLRQGLE 210
+ +K R I PN GF +QL A ++LR+ LE
Sbjct: 116 EAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQLE 151
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 73.2 bits (178), Expect = 2e-13
Identities = 55/146 (37%), Positives = 78/146 (53%), Gaps = 13/146 (8%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGV---EAHD 120
++ L+L + AN++ L IT ++NAS E GI+Y+ V +A D
Sbjct: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE-----GIQYIKVPVTDARD 78
Query: 121 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK 180
S +D F AD IH + G+ L+HC GVSRSA+L LAYLM YH ++L++A
Sbjct: 79 SRLYDF---FDPIADLIH-TIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHT 134
Query: 181 KVKDHRGII-PNRGFLRQLLALDRRL 205
K R II PN GF QL+ + +L
Sbjct: 135 WTKSRRPIIRPNNGFWEQLINYEFKL 160
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 72.0 bits (175), Expect = 3e-13
Identities = 49/128 (38%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Query: 83 LRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALS 142
++RL I +V+N + YE Y + A DS ++ +F+ A +FI A
Sbjct: 1 MQRLNIGYVINVTTHL---PLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEA-H 56
Query: 143 QPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGII-PNRGFLRQLLAL 201
Q G +L+HC GVSRSAT+V+AYLM + +T+ +A K VK R II PN F+ QLL
Sbjct: 57 QCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEF 116
Query: 202 DRRLRQGL 209
+ L G+
Sbjct: 117 EEDLNNGV 124
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 72.0 bits (175), Expect = 3e-13
Identities = 49/128 (38%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Query: 83 LRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALS 142
++RL I +V+N + YE Y + A DS ++ +F+ A +FI A
Sbjct: 1 MQRLNIGYVINVTTHL---PLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEA-H 56
Query: 143 QPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGII-PNRGFLRQLLAL 201
Q G +L+HC GVSRSAT+V+AYLM + +T+ +A K VK R II PN F+ QLL
Sbjct: 57 QCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEF 116
Query: 202 DRRLRQGL 209
+ L G+
Sbjct: 117 EEDLNNGV 124
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 71.2 bits (173), Expect = 6e-13
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Query: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
+++ ++LG + A+N +L+ G+ ++LN + P +E Y + +D A
Sbjct: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFE-----YHNIRVYDEEA 364
Query: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
D+ ++ FI +A + G K LVHC +GVSRSA+ V+AY M + L A VK
Sbjct: 365 TDLLAYWNDTYKFISKA-KKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVK 423
Query: 184 DHRGII-PNRGFLRQL 198
+ R + PN F+RQL
Sbjct: 424 ERRTVTKPNPSFMRQL 439
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 70.9 bits (172), Expect = 8e-13
Identities = 48/146 (32%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 67 PGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDM 126
P L LG QD A++ L++ +TH+LN ++ G A+ Y + D P ++
Sbjct: 71 PWLLLGSQDAAHDLDTLKKNKVTHILNVAY----GVENAFLS-DFTYKSISILDLPETNI 125
Query: 127 SIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 186
+F +FI A + G +LVHC GVSR+A +V+ +LM + A VK+ R
Sbjct: 126 LSYFPECFEFIEEA-KRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNAR 184
Query: 187 -GIIPNRGFLRQLLALDRRLRQGLEA 211
I PN GF+ QL R ++G E+
Sbjct: 185 PSICPNSGFMEQL----RTYQEGKES 206
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 70.5 bits (171), Expect = 1e-12
Identities = 49/143 (34%), Positives = 78/143 (54%), Gaps = 6/143 (4%)
Query: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
+ P LYLG Q N+ + + GI++VLNAS+S P+ R++ V +D+
Sbjct: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNS----CPKPDFICESRFMRVPINDNYCE 219
Query: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
+ + +FI +A +++VHC G+SRSAT+ +AY+M ++ +A + VKD
Sbjct: 220 KLLPWLDKSIEFIDKA-KLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKD 278
Query: 185 HR-GIIPNRGFLRQLLALDRRLR 206
R I PN FL QLL +R L+
Sbjct: 279 RRPSISPNFNFLGQLLEYERSLK 301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,906,744
Number of Sequences: 37866
Number of extensions: 324147
Number of successful extensions: 952
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 828
Number of HSP's gapped (non-prelim): 84
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.