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Search of human proteins with 4504835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504835 potassium inwardly-rectifying channel J2 [Homo
sapiens]
(427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 867 0.0
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 624 e-179
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 613 e-176
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 593 e-169
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 593 e-169
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 593 e-169
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 523 e-148
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 523 e-148
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 504 e-143
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 504 e-143
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 387 e-108
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 382 e-106
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 381 e-106
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 379 e-105
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 335 6e-92
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 332 4e-91
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 322 3e-88
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 322 3e-88
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 322 3e-88
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 322 3e-88
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 322 3e-88
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 321 9e-88
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 321 9e-88
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 321 9e-88
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 274 1e-73
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 274 1e-73
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 274 1e-73
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 268 9e-72
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 197 1e-50
gi|194239633 solute carrier family 44, member 5 isoform B [Homo ... 34 0.22
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 867 bits (2240), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN 60
MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
Sbjct: 1 MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN 60
Query: 61 VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK 120
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK
Sbjct: 61 VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK 120
Query: 121 ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM 180
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
Sbjct: 121 ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM 180
Query: 181 AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG 240
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
Sbjct: 181 AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG 240
Query: 241 EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG 300
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
Sbjct: 241 EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG 300
Query: 301 MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD 360
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
Sbjct: 301 MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD 360
Query: 361 LAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRP 420
LAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRP
Sbjct: 361 LAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRP 420
Query: 421 LRRESEI 427
LRRESEI
Sbjct: 421 LRRESEI 427
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 624 bits (1610), Expect = e-179
Identities = 305/431 (70%), Positives = 361/431 (83%), Gaps = 11/431 (2%)
Query: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
R N YSIVSSEEDG+ L TM+ ANGFGNGK VHTR++CR+RFVKK+G CN++F N+ EK
Sbjct: 6 RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIEFANMDEK 63
Query: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121
QRYLAD+FTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+
Sbjct: 64 SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPA-EGRGRTP 122
Query: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181
CV +V+ F AAFLFSIETQTTIGYG RCVT+ECP+AVFMVV QSIVGCIID+F+IGA+MA
Sbjct: 123 CVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMA 182
Query: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241
KMA+PKKR +TL+FSHNAV+A+RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 183 KMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGE 242
Query: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301
YIPLDQIDI+VGFD G+DRIFLVSPITI+HEIDE SPL+ +S+QD++ DFEIVVILEGM
Sbjct: 243 YIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGM 302
Query: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361
VEATAMTTQ RSSYLANEILWGHR+EPVLFEEK+ YK+DYS FHKTYEVP+TP CSA+DL
Sbjct: 303 VEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDL 362
Query: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416
E K++L +ANSFCYENE+A S++E+D +G + S D D D L
Sbjct: 363 VENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVL 422
Query: 417 EPRPLRRESEI 427
E RP RRESEI
Sbjct: 423 EQRPYRRESEI 433
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 613 bits (1581), Expect = e-176
Identities = 302/430 (70%), Positives = 355/430 (82%), Gaps = 9/430 (2%)
Query: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
R N YSIVS EEDG+ L TM+ ANGFGNGK VHTR++CR+RFVKK+G CN+ F N+ EK
Sbjct: 6 RANPYSIVSLEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIAFANMDEK 63
Query: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLD-ASKEGKA-C 122
QRYLAD+FTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ A G+ C
Sbjct: 64 SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGRTPC 123
Query: 123 VSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAK 182
V +V+ F AAFLFSIETQTTIGYG RCVT+EC +AVFMVV QSIVGCIID+F+IGA+MAK
Sbjct: 124 VMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAK 183
Query: 183 MAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEY 242
MA+PKKR TL+FSHNAV+A+RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K R+T EGEY
Sbjct: 184 MARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEY 243
Query: 243 IPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMV 302
IPLDQIDI+VGFD G+DRIFLVSPITI+HEIDE SPL+ +S+QD++ DFEIVVILEGMV
Sbjct: 244 IPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMV 303
Query: 303 EATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLA 362
EATAMTTQ RSSYLANEILWGHR+EPVLFEEK+ YK+DYS FHKTYEVP+TP CSA+DL
Sbjct: 304 EATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLV 363
Query: 363 EKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPLE 417
E K++L +ANSFCYENE+A S++E+D +G + S D D D LE
Sbjct: 364 ENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLE 423
Query: 418 PRPLRRESEI 427
RP RR SEI
Sbjct: 424 QRPYRRGSEI 433
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 593 bits (1528), Expect = e-169
Identities = 291/431 (67%), Positives = 350/431 (81%), Gaps = 12/431 (2%)
Query: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
R N YSIVSSEEDG+ L TM+ ANGFGNGK VHTR++C +RFVKK+G CN++F N+ EK
Sbjct: 6 RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCHNRFVKKNGQCNIEFANMDEK 63
Query: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121
QRYLADIFTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+
Sbjct: 64 SQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPA-EGRGRTP 122
Query: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181
CV +V+ F AAFLFSI+TQ TI YG RCVT+ECP+AVFMVV QSIVGCII++F+IGA+MA
Sbjct: 123 CVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMA 182
Query: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241
KM +PKKR +TL+FSHNAV+A+RDGKLC MWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 183 KMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGE 242
Query: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301
YIPLDQIDI+VGFD G+D FLVSPITI+HEIDE SPL+ +S+QD+ DFEIV+ILEG+
Sbjct: 243 YIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGI 302
Query: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361
VEATAMTTQ RSSYLANEILWGHR+EPVLF EK+ YK+DY FHKTYEVP+TP CSA+DL
Sbjct: 303 VEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDL 361
Query: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416
E K++L ANSFCY+NE+A S++E+D +G + S + D D L
Sbjct: 362 VENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVL 421
Query: 417 EPRPLRRESEI 427
E RP RRESEI
Sbjct: 422 EQRPYRRESEI 432
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 593 bits (1528), Expect = e-169
Identities = 291/431 (67%), Positives = 350/431 (81%), Gaps = 12/431 (2%)
Query: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
R N YSIVSSEEDG+ L TM+ ANGFGNGK VHTR++C +RFVKK+G CN++F N+ EK
Sbjct: 108 RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCHNRFVKKNGQCNIEFANMDEK 165
Query: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121
QRYLADIFTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+
Sbjct: 166 SQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPA-EGRGRTP 224
Query: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181
CV +V+ F AAFLFSI+TQ TI YG RCVT+ECP+AVFMVV QSIVGCII++F+IGA+MA
Sbjct: 225 CVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMA 284
Query: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241
KM +PKKR +TL+FSHNAV+A+RDGKLC MWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 285 KMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGE 344
Query: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301
YIPLDQIDI+VGFD G+D FLVSPITI+HEIDE SPL+ +S+QD+ DFEIV+ILEG+
Sbjct: 345 YIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGI 404
Query: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361
VEATAMTTQ RSSYLANEILWGHR+EPVLF EK+ YK+DY FHKTYEVP+TP CSA+DL
Sbjct: 405 VEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDL 463
Query: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416
E K++L ANSFCY+NE+A S++E+D +G + S + D D L
Sbjct: 464 VENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVL 523
Query: 417 EPRPLRRESEI 427
E RP RRESEI
Sbjct: 524 EQRPYRRESEI 534
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 593 bits (1528), Expect = e-169
Identities = 291/431 (67%), Positives = 350/431 (81%), Gaps = 12/431 (2%)
Query: 5 RTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEK 64
R N YSIVSSEEDG+ L TM+ ANGFGNGK VHTR++C +RFVKK+G CN++F N+ EK
Sbjct: 6 RANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCHNRFVKKNGQCNIEFANMDEK 63
Query: 65 GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGKA--- 121
QRYLADIFTTCVDIRWR+ML+IF LAF+ SWL FG +FW+IA+ HGDL+ + EG+
Sbjct: 64 SQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPA-EGRGRTP 122
Query: 122 CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMA 181
CV +V+ F AAFLFSI+TQ TI YG RCVT+ECP+AVFMVV QSIVGCII++F+IGA+MA
Sbjct: 123 CVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMA 182
Query: 182 KMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGE 241
KM +PKKR +TL+FSHNAV+A+RDGKLC MWRVGNLRKSH+VEAHVRAQL+K R+T EGE
Sbjct: 183 KMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGE 242
Query: 242 YIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGM 301
YIPLDQIDI+VGFD G+D FLVSPITI+HEIDE SPL+ +S+QD+ DFEIV+ILEG+
Sbjct: 243 YIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGI 302
Query: 302 VEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDL 361
VEATAMTTQ RSSYLANEILWGHR+EPVLF EK+ YK+DY FHKTYEVP+TP CSA+DL
Sbjct: 303 VEATAMTTQARSSYLANEILWGHRFEPVLF-EKNQYKIDYLHFHKTYEVPSTPRCSAKDL 361
Query: 362 AEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD-----TPPDIDLHNQASVPL 416
E K++L ANSFCY+NE+A S++E+D +G + S + D D L
Sbjct: 362 VENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGGVL 421
Query: 417 EPRPLRRESEI 427
E RP RRESEI
Sbjct: 422 EQRPYRRESEI 432
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 523 bits (1347), Expect = e-148
Identities = 266/440 (60%), Positives = 325/440 (73%), Gaps = 45/440 (10%)
Query: 32 NGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLA 91
NG++ V R++ R+RFVKK+G CNV F N+ K QRY+ADIFTTCVD RWR+ML+IF A
Sbjct: 7 NGQAHVPRRKR-RNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAA 65
Query: 92 FVLSWLFFGCVFWLIALLHGDLDASK------------------EGKACVSEVNSFTAAF 133
F++SWLFFG +FW IA HGDL+AS K C+ VN F AF
Sbjct: 66 FLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAF 125
Query: 134 LFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETL 193
LFS+ETQTTIGYGFRCVT+ECP+AV VV QSIVGC+ID+F+IG +MAKMA+PKKR +TL
Sbjct: 126 LFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTL 185
Query: 194 VFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVG 253
+FSH+AVI++RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K +T EGEY+PLDQ D+NVG
Sbjct: 186 LFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVG 245
Query: 254 FDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRS 313
+D G+DRIFLVSPI IVHEIDEDSPLY + K+++++ DFEIVVILEGMVEATAMTTQ RS
Sbjct: 246 YDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARS 305
Query: 314 SYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNA-- 371
SYLA+EILWGHR+EPV+FEEK +YKVDYSRFHKTYEV TP CSAR+L E K + A
Sbjct: 306 SYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPP 365
Query: 372 ---NSFCYENEVALTSKEEDDSENGVPESTST--------------------DTPPDIDL 408
++FCYENE+AL S+EE++ E + + + +DL
Sbjct: 366 PPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDL 425
Query: 409 HN-QASVPLEPRPLRRESEI 427
QAS+PL+ RRES I
Sbjct: 426 ERMQASLPLDNISYRRESAI 445
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 523 bits (1347), Expect = e-148
Identities = 266/440 (60%), Positives = 325/440 (73%), Gaps = 45/440 (10%)
Query: 32 NGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLA 91
NG++ V R++ R+RFVKK+G CNV F N+ K QRY+ADIFTTCVD RWR+ML+IF A
Sbjct: 7 NGQAHVPRRKR-RNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAA 65
Query: 92 FVLSWLFFGCVFWLIALLHGDLDASK------------------EGKACVSEVNSFTAAF 133
F++SWLFFG +FW IA HGDL+AS K C+ VN F AF
Sbjct: 66 FLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAF 125
Query: 134 LFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETL 193
LFS+ETQTTIGYGFRCVT+ECP+AV VV QSIVGC+ID+F+IG +MAKMA+PKKR +TL
Sbjct: 126 LFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTL 185
Query: 194 VFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVG 253
+FSH+AVI++RDGKLCLMWRVGNLRKSH+VEAHVRAQL+K +T EGEY+PLDQ D+NVG
Sbjct: 186 LFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVG 245
Query: 254 FDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRS 313
+D G+DRIFLVSPI IVHEIDEDSPLY + K+++++ DFEIVVILEGMVEATAMTTQ RS
Sbjct: 246 YDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARS 305
Query: 314 SYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNA-- 371
SYLA+EILWGHR+EPV+FEEK +YKVDYSRFHKTYEV TP CSAR+L E K + A
Sbjct: 306 SYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLPAPP 365
Query: 372 ---NSFCYENEVALTSKEEDDSENGVPESTST--------------------DTPPDIDL 408
++FCYENE+AL S+EE++ E + + + +DL
Sbjct: 366 PPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDL 425
Query: 409 HN-QASVPLEPRPLRRESEI 427
QAS+PL+ RRES I
Sbjct: 426 ERMQASLPLDNISYRRESAI 445
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 504 bits (1298), Expect = e-143
Identities = 239/368 (64%), Positives = 290/368 (78%), Gaps = 9/368 (2%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R RFVKKDGHCNV+F+N+G +G RYL+D+FTTCVD+RWRWM ++F +F+ SWL FG F
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 104 WLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF 163
WLIA LHGDL A C S V SF AAFLF++ETQT+IGYG R VT+ECP AV VV
Sbjct: 109 WLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVL 168
Query: 164 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV 223
Q I GC++DAF++GAVMAKMAKPKKRNETLVFS NAV+A+RD +LCLMWRVGNLR+SHLV
Sbjct: 169 QCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLV 228
Query: 224 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS 283
EAHVRAQLL+ R+T EGEYIPLD D++VGFD G DRIFLVSPITIVHEID SPLY+L
Sbjct: 229 EAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELG 288
Query: 284 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR 343
+ ++ ADFE+VVILEGMVEATAMTTQCRSSYL E+LWGHR+EPVLF+ Y+VDY
Sbjct: 289 RAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRH 348
Query: 344 FHKTYEVPNTPLCSARDLAEKKYILSNA---------NSFCYENEVALTSKEEDDSENGV 394
FH+TYEVP TP+CSA++L E+ S++ +FCYENE+AL+ +E+D ++
Sbjct: 349 FHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDET 408
Query: 395 PESTSTDT 402
E +T
Sbjct: 409 EEGNGVET 416
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 504 bits (1298), Expect = e-143
Identities = 239/368 (64%), Positives = 290/368 (78%), Gaps = 9/368 (2%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R RFVKKDGHCNV+F+N+G +G RYL+D+FTTCVD+RWRWM ++F +F+ SWL FG F
Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108
Query: 104 WLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF 163
WLIA LHGDL A C S V SF AAFLF++ETQT+IGYG R VT+ECP AV VV
Sbjct: 109 WLIASLHGDLAAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVL 168
Query: 164 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV 223
Q I GC++DAF++GAVMAKMAKPKKRNETLVFS NAV+A+RD +LCLMWRVGNLR+SHLV
Sbjct: 169 QCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLV 228
Query: 224 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS 283
EAHVRAQLL+ R+T EGEYIPLD D++VGFD G DRIFLVSPITIVHEID SPLY+L
Sbjct: 229 EAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELG 288
Query: 284 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR 343
+ ++ ADFE+VVILEGMVEATAMTTQCRSSYL E+LWGHR+EPVLF+ Y+VDY
Sbjct: 289 RAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRH 348
Query: 344 FHKTYEVPNTPLCSARDLAEKKYILSNA---------NSFCYENEVALTSKEEDDSENGV 394
FH+TYEVP TP+CSA++L E+ S++ +FCYENE+AL+ +E+D ++
Sbjct: 349 FHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDET 408
Query: 395 PESTSTDT 402
E +T
Sbjct: 409 EEGNGVET 416
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 387 bits (995), Expect = e-108
Identities = 183/324 (56%), Positives = 253/324 (78%), Gaps = 4/324 (1%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R R+++K G CNV NV E RYL+D+FTT VD++WR+ L++F + + ++WLFFG ++
Sbjct: 50 RQRYMEKSGKCNVHHGNVQET-YRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIW 108
Query: 104 WLIALLHGDLD--ASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMV 161
WLIA + GDLD +E CV ++ F +AFLFSIET+TTIGYGFR +T++CP + ++
Sbjct: 109 WLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILL 168
Query: 162 VFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSH 221
+ Q+I+G I++AF++G + K+++PKKR ETL+FS+NAVI+MRD KLCLM+RVG+LR SH
Sbjct: 169 LVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSH 228
Query: 222 LVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYD 281
+VEA +RA+L+KSR T EGE+IPL+Q DINVGFD+G DR+FLVSP+ I HEI++ SP ++
Sbjct: 229 IVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWE 288
Query: 282 LSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDY 341
+S+ + +FE+VVILEGMVEAT MT Q RSSY+ E+LWGHR+ PVL EK +Y+VDY
Sbjct: 289 MSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDY 348
Query: 342 SRFHKTYEVPNTPLCSARDLAEKK 365
+ FH TYE NTP C A++LAE K
Sbjct: 349 NTFHDTYET-NTPSCCAKELAEMK 371
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 382 bits (982), Expect = e-106
Identities = 185/326 (56%), Positives = 253/326 (77%), Gaps = 4/326 (1%)
Query: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
R++ R R+V+KDG CNVQ NV E RYL D+FTT VD++WR L+ F LA+ L+WLFF
Sbjct: 17 RRRGRQRYVEKDGRCNVQQGNVRET-YRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFF 75
Query: 100 GCVFWLIALLHGDLDASKEGK--ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIA 157
G ++WLIA GDL+ ++ CV+ +N F AAFLFSIET+TTIGYG R +TD+CP
Sbjct: 76 GAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135
Query: 158 VFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNL 217
+ +++ Q+I+G +++AF++G + K+++P KR TLVFS +AV+++RDG+LCLM+RVG+L
Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195
Query: 218 RKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDS 277
R SH+VEA +RA+L++SR T EGE+IPL Q D++VGFD+G DR+FLVSP+ I HEID S
Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255
Query: 278 PLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYY 337
P ++ S++ ++ DFEIVVILEGMVEAT MT Q RSSYL +E+LWGHR+ VL E +Y
Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFY 315
Query: 338 KVDYSRFHKTYEVPNTPLCSARDLAE 363
+VDY+ FH+T+EVP TP CSAR+LAE
Sbjct: 316 EVDYASFHETFEVP-TPSCSARELAE 340
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 381 bits (979), Expect = e-106
Identities = 182/320 (56%), Positives = 252/320 (78%), Gaps = 4/320 (1%)
Query: 46 RFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWL 105
R+V+KDG CNV NV E RYL DIFTT VD++WR+ L+IF + + ++WLFFG ++WL
Sbjct: 55 RYVRKDGKCNVHHGNVRET-YRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWL 113
Query: 106 IALLHGDLDASKEGK--ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF 163
IA + GD+D ++ CV+ +N F +AFLFSIET+TTIGYG+R +TD+CP + +++
Sbjct: 114 IAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLI 173
Query: 164 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV 223
QS++G I++AF++G + K+++PKKR ETLVFS +AVI+MRDGKLCLM+RVG+LR SH+V
Sbjct: 174 QSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIV 233
Query: 224 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS 283
EA +RA+L+KS+ TSEGE+IPL+Q DINVG+ +G DR+FLVSP+ I HEI++ SP +++S
Sbjct: 234 EASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEIS 293
Query: 284 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR 343
K + + EIVVILEGMVEAT MT Q RSSY+ +EILWG+R+ PVL E +Y+VDY+
Sbjct: 294 KAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNS 353
Query: 344 FHKTYEVPNTPLCSARDLAE 363
FH+TYE +TP SA++LAE
Sbjct: 354 FHETYET-STPSLSAKELAE 372
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 379 bits (973), Expect = e-105
Identities = 182/348 (52%), Positives = 250/348 (71%), Gaps = 6/348 (1%)
Query: 9 YSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRY 68
Y +V++ G L G G + ++ R RFV K+G CNVQ N+G + RY
Sbjct: 12 YQVVTTSSSGSGLQPQ----GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRY 67
Query: 69 LADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK--ACVSEV 126
L+D+FTT VD++WRW L IF L + ++WLF ++W+IA GDL+ + G CV+ V
Sbjct: 68 LSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANV 127
Query: 127 NSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKP 186
+F +AFLF IET+ TIGYG+R +TD+CP + + +FQSI+G I+DAF+IG + KM++P
Sbjct: 128 YNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQP 187
Query: 187 KKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLD 246
KKR ETL+FS +AVI+MRDGKL LM+RVGNLR SH+V A +R +LLKSR T EGE++PLD
Sbjct: 188 KKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLD 247
Query: 247 QIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATA 306
Q++++VGF +G D++FLVSP+TI H ID SP YDLS++ + FEIVVILEG+VE T
Sbjct: 248 QLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTG 307
Query: 307 MTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTP 354
MT Q R+SY +E+LWGHR+ PV+ E+ ++KVDYS+FH T+EVP P
Sbjct: 308 MTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPP 355
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 335 bits (858), Expect = 6e-92
Identities = 168/335 (50%), Positives = 233/335 (69%), Gaps = 12/335 (3%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
++RF+ K G CN+ N+ E+G R+L DIFTT VD++WR LVIF ++F+ SWL F ++
Sbjct: 33 KARFIAKSGACNLAHKNIREQG-RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91
Query: 104 WLIALLHGDLDA----------SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
WL+A HGD+ A E CV+ V SFT+AFLFSIE Q TIG+G R +T+E
Sbjct: 92 WLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEE 151
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
CP+A+ +++ Q+IVG II+A ++G + K A+ +R ETL+FS +AVIA+R+GKLC M+R
Sbjct: 152 CPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFR 211
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
VG+LRKS ++ A VR Q++K T EGE +P+ Q+DI V + IFLV+P+ I H I
Sbjct: 212 VGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVI 271
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D+ SPLYD+S D+ N D E++VILEG+VE T +TTQ R+SY+A EI WGHR+ ++ EE
Sbjct: 272 DKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEE 331
Query: 334 KHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYIL 368
+ Y VDYS+F T +V P CSAR+L EK IL
Sbjct: 332 EGVYSVDYSKFGNTVKVA-APRCSARELDEKPSIL 365
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 332 bits (851), Expect = 4e-91
Identities = 171/338 (50%), Positives = 240/338 (71%), Gaps = 7/338 (2%)
Query: 34 KSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFV 93
K + RQ+ R+RFV K G+CNV N+ E+G R+L D+FTT VD++W L+IF ++F+
Sbjct: 23 KPRYRARQR-RARFVSKKGNCNVAHKNIREQG-RFLQDVFTTLVDLKWPHTLLIFTMSFL 80
Query: 94 LSWLFFGCVFWLIALLHGDLDASKEGKA--CVSEVNSFTAAFLFSIETQTTIGYGFRCVT 151
SWL F +WLIA HGDL A EG A CV+ ++SF++AFLFSIE Q TIG+G R VT
Sbjct: 81 CSWLLFAMAWWLIAFAHGDL-APSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVT 139
Query: 152 DECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLM 211
+ECP+A+ +++ Q+IVG +I+A ++G + K A+ +R ETL+FS +AVIA+R G+LC M
Sbjct: 140 EECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFM 199
Query: 212 WRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVH 271
RVG+LRKS ++ A + Q+++ + EGE +PL Q+DI + G + IFLV+P+ I H
Sbjct: 200 LRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYH 259
Query: 272 EIDEDSPLYDLSKQDI-DNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVL 330
ID +SPLYDL+ D+ + D EI+VILEG+VE T +TTQ R+SYLA+EILWG R+ P++
Sbjct: 260 VIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIV 319
Query: 331 FEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYIL 368
EE Y VDYS+F T +VP TPLC+AR L E +L
Sbjct: 320 AEEDGRYSVDYSKFGNTVKVP-TPLCTARQLDEDHSLL 356
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 322 bits (826), Expect = 3e-88
Identities = 163/359 (45%), Positives = 241/359 (67%), Gaps = 8/359 (2%)
Query: 38 HTRQQCRSRFVKKDGHCNVQFINVGEKGQR-YLADIFTTCVDIRWRWMLVIFCLAFVLSW 96
H+RQ R+R V KDG CN++F NV + + + DI+TT +D++WR+ + IF AF+ SW
Sbjct: 16 HSRQ--RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 97 LFFGCVFWLIALLHGDLDA---SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
FFG +++ +A +H DL S CV +N T+AFLFS+ETQ TIGYGFRCVT++
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
C A+F+++FQSI+G II++F+ GA++AK+++PKKR +T+ FS NAVI+ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
V NLRKS L+ +H+ +LLK+ +T EGE I LDQI+IN D+G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D +SP + ++ + + DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+R+ P++ +
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 334 KH-YYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSE 391
K Y+VD+ F KT EV TP C+ EK + N + E DD++
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTK 371
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 322 bits (826), Expect = 3e-88
Identities = 163/359 (45%), Positives = 241/359 (67%), Gaps = 8/359 (2%)
Query: 38 HTRQQCRSRFVKKDGHCNVQFINVGEKGQR-YLADIFTTCVDIRWRWMLVIFCLAFVLSW 96
H+RQ R+R V KDG CN++F NV + + + DI+TT +D++WR+ + IF AF+ SW
Sbjct: 16 HSRQ--RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 97 LFFGCVFWLIALLHGDLDA---SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
FFG +++ +A +H DL S CV +N T+AFLFS+ETQ TIGYGFRCVT++
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
C A+F+++FQSI+G II++F+ GA++AK+++PKKR +T+ FS NAVI+ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
V NLRKS L+ +H+ +LLK+ +T EGE I LDQI+IN D+G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D +SP + ++ + + DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+R+ P++ +
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 334 KH-YYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSE 391
K Y+VD+ F KT EV TP C+ EK + N + E DD++
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTK 371
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 322 bits (826), Expect = 3e-88
Identities = 163/359 (45%), Positives = 241/359 (67%), Gaps = 8/359 (2%)
Query: 38 HTRQQCRSRFVKKDGHCNVQFINVGEKGQR-YLADIFTTCVDIRWRWMLVIFCLAFVLSW 96
H+RQ R+R V KDG CN++F NV + + + DI+TT +D++WR+ + IF AF+ SW
Sbjct: 35 HSRQ--RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 92
Query: 97 LFFGCVFWLIALLHGDLDA---SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
FFG +++ +A +H DL S CV +N T+AFLFS+ETQ TIGYGFRCVT++
Sbjct: 93 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 152
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
C A+F+++FQSI+G II++F+ GA++AK+++PKKR +T+ FS NAVI+ R GKLCL+ R
Sbjct: 153 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 212
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
V NLRKS L+ +H+ +LLK+ +T EGE I LDQI+IN D+G + +F +SP+TI H I
Sbjct: 213 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 272
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D +SP + ++ + + DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+R+ P++ +
Sbjct: 273 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 332
Query: 334 KH-YYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSE 391
K Y+VD+ F KT EV TP C+ EK + N + E DD++
Sbjct: 333 KEGKYRVDFHNFSKTVEV-ETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTK 390
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 322 bits (826), Expect = 3e-88
Identities = 163/359 (45%), Positives = 241/359 (67%), Gaps = 8/359 (2%)
Query: 38 HTRQQCRSRFVKKDGHCNVQFINVGEKGQR-YLADIFTTCVDIRWRWMLVIFCLAFVLSW 96
H+RQ R+R V KDG CN++F NV + + + DI+TT +D++WR+ + IF AF+ SW
Sbjct: 16 HSRQ--RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 97 LFFGCVFWLIALLHGDLDA---SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
FFG +++ +A +H DL S CV +N T+AFLFS+ETQ TIGYGFRCVT++
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
C A+F+++FQSI+G II++F+ GA++AK+++PKKR +T+ FS NAVI+ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
V NLRKS L+ +H+ +LLK+ +T EGE I LDQI+IN D+G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D +SP + ++ + + DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+R+ P++ +
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 334 KH-YYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSE 391
K Y+VD+ F KT EV TP C+ EK + N + E DD++
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTK 371
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 322 bits (826), Expect = 3e-88
Identities = 163/359 (45%), Positives = 241/359 (67%), Gaps = 8/359 (2%)
Query: 38 HTRQQCRSRFVKKDGHCNVQFINVGEKGQR-YLADIFTTCVDIRWRWMLVIFCLAFVLSW 96
H+RQ R+R V KDG CN++F NV + + + DI+TT +D++WR+ + IF AF+ SW
Sbjct: 16 HSRQ--RARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSW 73
Query: 97 LFFGCVFWLIALLHGDLDA---SKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDE 153
FFG +++ +A +H DL S CV +N T+AFLFS+ETQ TIGYGFRCVT++
Sbjct: 74 FFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQ 133
Query: 154 CPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWR 213
C A+F+++FQSI+G II++F+ GA++AK+++PKKR +T+ FS NAVI+ R GKLCL+ R
Sbjct: 134 CATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIR 193
Query: 214 VGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEI 273
V NLRKS L+ +H+ +LLK+ +T EGE I LDQI+IN D+G + +F +SP+TI H I
Sbjct: 194 VANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVI 253
Query: 274 DEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEE 333
D +SP + ++ + + DFE+VV L+G VE+T+ T Q R+SY+ E+LWG+R+ P++ +
Sbjct: 254 DHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT 313
Query: 334 KH-YYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSE 391
K Y+VD+ F KT EV TP C+ EK + N + E DD++
Sbjct: 314 KEGKYRVDFHNFSKTVEV-ETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTK 371
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 321 bits (822), Expect = 9e-88
Identities = 166/322 (51%), Positives = 222/322 (68%), Gaps = 6/322 (1%)
Query: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
+++ R R + KDG CNV F ++ + Y+ DIFTT VD +WR M VIF L+++LSWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 100 GCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVF 159
G VFWLIA HGDL + CV V+SFT AFLFS+ETQTTIGYG+RCVT+EC +AV
Sbjct: 89 GSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 160 MVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRK 219
MV+ QSI+ CII+ FIIGA +AKMA +KR +T+ FS+ A+I MRDGKLCLMWR+G+ R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 220 SHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPL 279
+H+VE VRAQLL+ SEG + + D+ + D+I LV+P+TIVHEID +SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 280 YDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKV 339
Y L ++ + +FEI+V ++T + Q RSSY+ EILWGHR+ VL ++ YYKV
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKV 323
Query: 340 DYSRFHKTYEVPNTPLCSARDL 361
+ +F + EV P CSA+ L
Sbjct: 324 NCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 321 bits (822), Expect = 9e-88
Identities = 166/322 (51%), Positives = 222/322 (68%), Gaps = 6/322 (1%)
Query: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
+++ R R + KDG CNV F ++ + Y+ DIFTT VD +WR M VIF L+++LSWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 100 GCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVF 159
G VFWLIA HGDL + CV V+SFT AFLFS+ETQTTIGYG+RCVT+EC +AV
Sbjct: 89 GSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 160 MVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRK 219
MV+ QSI+ CII+ FIIGA +AKMA +KR +T+ FS+ A+I MRDGKLCLMWR+G+ R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 220 SHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPL 279
+H+VE VRAQLL+ SEG + + D+ + D+I LV+P+TIVHEID +SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 280 YDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKV 339
Y L ++ + +FEI+V ++T + Q RSSY+ EILWGHR+ VL ++ YYKV
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKV 323
Query: 340 DYSRFHKTYEVPNTPLCSARDL 361
+ +F + EV P CSA+ L
Sbjct: 324 NCLQFEGSVEV-YAPFCSAKQL 344
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 321 bits (822), Expect = 9e-88
Identities = 166/322 (51%), Positives = 222/322 (68%), Gaps = 6/322 (1%)
Query: 40 RQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFF 99
+++ R R + KDG CNV F ++ + Y+ DIFTT VD +WR M VIF L+++LSWL F
Sbjct: 29 KRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIF 88
Query: 100 GCVFWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVF 159
G VFWLIA HGDL + CV V+SFT AFLFS+ETQTTIGYG+RCVT+EC +AV
Sbjct: 89 GSVFWLIAFHHGDLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVL 148
Query: 160 MVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRK 219
MV+ QSI+ CII+ FIIGA +AKMA +KR +T+ FS+ A+I MRDGKLCLMWR+G+ R
Sbjct: 149 MVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRP 208
Query: 220 SHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPL 279
+H+VE VRAQLL+ SEG + + D+ + D+I LV+P+TIVHEID +SPL
Sbjct: 209 NHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 280 YDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKV 339
Y L ++ + +FEI+V ++T + Q RSSY+ EILWGHR+ VL ++ YYKV
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKV 323
Query: 340 DYSRFHKTYEVPNTPLCSARDL 361
+ +F + EV P CSA+ L
Sbjct: 324 NCLQFEGSVEV-YAPFCSAKQL 344
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 274 bits (700), Expect = 1e-73
Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R R + K GH NV+ V YL D++TT +D++WR+ L +F FV++W FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
+ IA +HGDL+ + C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
+V Q ++ +I+ FI G +AK+A+PKKR ET+ FSH AVI ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
L++ + +LL++ +T EGE I L+Q + DS + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339
DL+ Q++ +FE+VV+L VE+T+ Q R+SY+ EI WG + PV+ K+ Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366
D+S+F + + P+ T C S + E+KY
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 274 bits (700), Expect = 1e-73
Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R R + K GH NV+ V YL D++TT +D++WR+ L +F FV++W FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
+ IA +HGDL+ + C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
+V Q ++ +I+ FI G +AK+A+PKKR ET+ FSH AVI ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
L++ + +LL++ +T EGE I L+Q + DS + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339
DL+ Q++ +FE+VV+L VE+T+ Q R+SY+ EI WG + PV+ K+ Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366
D+S+F + + P+ T C S + E+KY
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 274 bits (700), Expect = 1e-73
Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R R + K GH NV+ V YL D++TT +D++WR+ L +F FV++W FG ++
Sbjct: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85
Query: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
+ IA +HGDL+ + C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+
Sbjct: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
+V Q ++ +I+ FI G +AK+A+PKKR ET+ FSH AVI ++GKLCL+ +V N+RKS
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
L++ + +LL++ +T EGE I L+Q + DS + FL+ P+T H +DE SPL
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265
Query: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339
DL+ Q++ +FE+VV+L VE+T+ Q R+SY+ EI WG + PV+ K+ Y
Sbjct: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325
Query: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366
D+S+F + + P+ T C S + E+KY
Sbjct: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 268 bits (684), Expect = 9e-72
Identities = 135/311 (43%), Positives = 202/311 (64%), Gaps = 5/311 (1%)
Query: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103
R R + KDG NV+ ++ +K YL D++TT +D++WR+ L++F F +W FG V+
Sbjct: 27 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVW 86
Query: 104 WLIALLHGDL---DASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
+L+A+ HGDL D CV +V++ T AFLFS+E+QTTIGYGFR +++ECP+A+ +
Sbjct: 87 YLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVL 146
Query: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
++ Q ++ I++ FI G +AK+A+PKKR ET+ FS +AV+A +GK CLM RV N+RKS
Sbjct: 147 LIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKS 206
Query: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
L+ V +LL++ T EGE I L+Q+++ D+ D FL+ P+T H +DE SPL
Sbjct: 207 LLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLK 266
Query: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVL-FEEKHYYKV 339
DL + DFE+V+IL G VE+T+ T Q R+SYL EILWG+ + P + Y
Sbjct: 267 DLPLRS-GEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIA 325
Query: 340 DYSRFHKTYEV 350
D+S F + +V
Sbjct: 326 DFSLFDQVVKV 336
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 197 bits (502), Expect = 1e-50
Identities = 119/318 (37%), Positives = 181/318 (56%), Gaps = 11/318 (3%)
Query: 46 RFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWL 105
R V KDGH +Q ++ ++G YL D + +D+RWRWM+++F +FV+ WL F ++++
Sbjct: 19 RMVTKDGHSTLQ-MDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
Query: 106 IALLHGDL----DASKEGKA-CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
+A ++GDL DA E CV + SFTAAF FS+ETQ TIGYG + +CP A+ +
Sbjct: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
Query: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
+ Q ++G +++AFI GA +AK+A+PK R ++ F+ AV+A DGK L+++V N R S
Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
Query: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
L V A L + R E + +D ++ S + F + P+T H I SPL
Sbjct: 198 PLTSVRVSAVLYQER---ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPLA 254
Query: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFE-EKHYYKV 339
L + + + + FE+VV L M E T Q R+SYL +EI+ H + +L K Y++
Sbjct: 255 TLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQI 313
Query: 340 DYSRFHKTYEVPNTPLCS 357
F KT TPL S
Sbjct: 314 KMENFDKTVPEFPTPLVS 331
>gi|194239633 solute carrier family 44, member 5 isoform B [Homo
sapiens]
Length = 717
Score = 34.3 bits (77), Expect = 0.22
Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 7/35 (20%)
Query: 81 WRWMLVIFCLAFVLSWLFF-------GCVFWLIAL 108
W W+L+ +A VLSW+F GC+FW+ +
Sbjct: 242 WYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,528,410
Number of Sequences: 37866
Number of extensions: 662169
Number of successful extensions: 1903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1806
Number of HSP's gapped (non-prelim): 49
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.