Search of human proteins with 4504333

Search of human proteins with 4504333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504333 histidine ammonia-lyase [Homo sapiens]
         (657 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504333 histidine ammonia-lyase [Homo sapiens]                    1310   0.0  
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ...    36   0.098
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ...    36   0.098
gi|119120897 par-3 partitioning defective 3 homolog B isoform b ...    36   0.098
gi|16445033 ACRC protein [Homo sapiens]                                34   0.37 
gi|16933565 protocadherin 21 precursor [Homo sapiens]                  34   0.49 
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        33   1.1  
gi|48928029 trafficking protein particle complex 10 [Homo sapiens]     32   1.4  
gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]          31   4.1  
gi|17196626 patatin-like phospholipase domain containing 3 [Homo...    30   5.4  

>gi|4504333 histidine ammonia-lyase [Homo sapiens]
          Length = 657

 Score = 1310 bits (3389), Expect = 0.0
 Identities = 657/657 (100%), Positives = 657/657 (100%)

Query: 1   MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKG 60
           MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKG
Sbjct: 1   MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKG 60

Query: 61  LGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDR 120
           LGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDR
Sbjct: 61  LGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDR 120

Query: 121 LTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKFARTVIPI 180
           LTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKFARTVIPI
Sbjct: 121 LTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKFARTVIPI 180

Query: 181 NKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEMFNAS 240
           NKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEMFNAS
Sbjct: 181 NKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEMFNAS 240

Query: 241 CLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSGWADAKYVLEAHGLKPVILKPK 300
           CLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSGWADAKYVLEAHGLKPVILKPK
Sbjct: 241 CLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSGWADAKYVLEAHGLKPVILKPK 300

Query: 301 EGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRG 360
           EGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRG
Sbjct: 301 EGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRG 360

Query: 361 QIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITT 420
           QIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITT
Sbjct: 361 QIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITT 420

Query: 421 ELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYLAIGIHELAAISERRIERLCNPSLS 480
           ELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYLAIGIHELAAISERRIERLCNPSLS
Sbjct: 421 ELNSATDNPMVFANRGETVSGGNFHGEYPAKALDYLAIGIHELAAISERRIERLCNPSLS 480

Query: 481 ELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAAR 540
           ELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAAR
Sbjct: 481 ELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAAR 540

Query: 541 KALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDI 600
           KALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDI
Sbjct: 541 KALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDI 600

Query: 601 EAAHRLLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLQFLHKKSTKIPESEDL 657
           EAAHRLLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLQFLHKKSTKIPESEDL
Sbjct: 601 EAAHRLLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLQFLHKKSTKIPESEDL 657


>gi|119120907 par-3 partitioning defective 3 homolog B isoform a
          [Homo sapiens]
          Length = 1104

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 13 LAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKGLGLLDNEDRLEV 72
          + VPC++ QL VG L ++A++RY+K +    G+      H L       G+LD +D L  
Sbjct: 12 IVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWV--KIHHL--EYTDGGILDPDDVLAD 67

Query: 73 ALENNEFVEVVIE 85
           +E+ + +  V E
Sbjct: 68 VVEDKDKLIAVFE 80


>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
          [Homo sapiens]
          Length = 1136

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 13 LAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKGLGLLDNEDRLEV 72
          + VPC++ QL VG L ++A++RY+K +    G+      H L       G+LD +D L  
Sbjct: 12 IVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWV--KIHHL--EYTDGGILDPDDVLAD 67

Query: 73 ALENNEFVEVVIE 85
           +E+ + +  V E
Sbjct: 68 VVEDKDKLIAVFE 80


>gi|119120897 par-3 partitioning defective 3 homolog B isoform b
          [Homo sapiens]
          Length = 1143

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 13 LAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKGLGLLDNEDRLEV 72
          + VPC++ QL VG L ++A++RY+K +    G+      H L       G+LD +D L  
Sbjct: 12 IVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWV--KIHHL--EYTDGGILDPDDVLAD 67

Query: 73 ALENNEFVEVVIE 85
           +E+ + +  V E
Sbjct: 68 VVEDKDKLIAVFE 80


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 24/226 (10%)

Query: 71  EVALENNEFVEVVIE-GDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDRLTTED---- 125
           ++A +  E VE         S D    Q  G  L     +PE   E+   +L TE+    
Sbjct: 346 QIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAP 405

Query: 126 -LVNLGKGRYKIK-LTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKF-ART----VI 178
            +   GK + K K +     KR  K++ +++   K +T    I     K  A+T    V 
Sbjct: 406 VVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVT 465

Query: 179 PINKLQELQVNLVRSHSSGVGKPLSPERCRML-LALRINVLAKGYSGISL-----ETLKQ 232
           P +K +        +      K  +P +C++    L+    +K YSG +L     E +++
Sbjct: 466 PGHKKRGPSKKKPGAAKVEKRKTRTP-KCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQR 524

Query: 233 VIEMFNAS-CLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPK 277
           + ++FN S C   +PEK  +G +  +   +    GL   G+MW PK
Sbjct: 525 IYDLFNRSVCDKKLPEKLRIGWNNKMVKTA----GLCSTGEMWYPK 566


>gi|16933565 protocadherin 21 precursor [Homo sapiens]
          Length = 859

 Score = 33.9 bits (76), Expect = 0.49
 Identities = 50/214 (23%), Positives = 78/214 (36%), Gaps = 48/214 (22%)

Query: 177 VIPINKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGIS-----LETLK 231
           V+P   L E QV ++  +S+ +    S      LLA+ +N   K  S        L+T  
Sbjct: 408 VVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTND 467

Query: 232 QVIEMFNASCLPYVPEKGTVGASGDLAPLSHLALGLVGEGKMWSPKSG-WADAKYVLEAH 290
            V +  +   +  +PE    G+       S +A+  V       P +G W + KY     
Sbjct: 468 NVPKFDSLYYVARIPENAPGGS-------SVVAVTAV------DPDTGPWGEVKYSTYGT 514

Query: 291 GLKPVILKPKEGLALINGTQMITSLGCEAVERASAIARQADIVAALTLEVLKGTTKAFDT 350
           G    ++ P  GL     TQ   SL  EA  R +   +  D+                  
Sbjct: 515 GADLFLIHPSTGLIY---TQPWASLDAEATARYNFYVKAEDM------------------ 553

Query: 351 DIHALRPHRGQIEVAFRFRSLLDSDHHPSEIAES 384
                    G+  VA  F +LLD + HP +  +S
Sbjct: 554 --------EGKYSVAEVFITLLDVNDHPPQFGKS 579


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 57  RCKGLGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIEL 116
           R   + L + E +L+ A  N E    + E DA+  + +    E   +     E  K I  
Sbjct: 115 RENSIELRELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAE---IAKTMMEEHKRIIK 171

Query: 117 DGDRLTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVV 163
           + +    ED  N  K +Y + L    E++ +K +E  + ++KEK ++
Sbjct: 172 EEN--AAEDKRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMI 216


>gi|48928029 trafficking protein particle complex 10 [Homo sapiens]
          Length = 1259

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 358 HRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQD 393
           H GQIE   +  SLL SDHH +E    H FC  + D
Sbjct: 531 HLGQIENYLQTSSLLASDHHLTEEERKH-FCQEILD 565


>gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]
          Length = 992

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 4/99 (4%)

Query: 318 EAVERASAIARQADIVAALTLEVLKGTTKAFDTDIHALRPHRGQIEVAFRFRSLLDSDHH 377
           +A+ER    A  A ++  L L+V + T        H L    G+ +++ R +  L +  H
Sbjct: 367 DALERTMGRAHMAKVIEFLKLQVQEETRCRLAAISHGLELLAGEGKLSGRQKEELLTQQH 426

Query: 378 PSEIAESHR----FCDRVQDAYTLRCCPQVHGVVNDTIA 412
            +   E+ R    F  R +D  T     QV G    T+A
Sbjct: 427 KAFWQEAERFSREFVQRGKDLVTASLAHQVEGTAKLTLA 465


>gi|17196626 patatin-like phospholipase domain containing 3 [Homo
           sapiens]
          Length = 481

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 44/203 (21%), Positives = 79/203 (38%), Gaps = 25/203 (12%)

Query: 342 KGTTKAFDTDIHALRPHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRC-C 400
           +G  K    ++H L    G+I +     SL       + +    R  D V DA    C  
Sbjct: 96  QGLCKCLPANVHQLIS--GKIGI-----SLTRVSDGENVLVSDFRSKDEVVDALVCSCFI 148

Query: 401 PQVHGVVNDTIAFVKNIITTELNSATDNPMVFANRGETVSGGNFHGEYP----AKALDYL 456
           P   G++  +   V+ +     +    + + F +   T++   F+GEY      K+ ++L
Sbjct: 149 PFYSGLIPPSFRGVRYV-----DGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFL 203

Query: 457 AIGIHELAAISERRIERLCNPSLSELP-AFLVAEGGLNSGFMIAHCTAAALVSENKALCH 515
            + I +L+        RLC  +L  L  AF+  +  +     +     A    E K +C+
Sbjct: 204 HVDITKLSL-------RLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICN 256

Query: 516 PSSVDSLSTSAATEDHVSMGGWA 538
                  S+S   +  V+M  WA
Sbjct: 257 RPQPGLKSSSEGMDPEVAMPSWA 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,944,259
Number of Sequences: 37866
Number of extensions: 1034755
Number of successful extensions: 2070
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2062
Number of HSP's gapped (non-prelim): 13
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.