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Search of human proteins with 4503417
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo
sapiens]
(394 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 794 0.0
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 514 e-146
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 456 e-128
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 286 3e-77
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 281 6e-76
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 182 5e-46
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 176 3e-44
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 169 4e-42
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 168 9e-42
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 167 2e-41
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 163 2e-40
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 111 1e-24
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 110 3e-24
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 110 3e-24
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 102 8e-22
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 102 8e-22
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 102 8e-22
gi|37674210 slingshot 2 [Homo sapiens] 99 5e-21
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 95 1e-19
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 91 2e-18
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 88 1e-17
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 85 1e-16
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 84 2e-16
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 84 2e-16
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 84 3e-16
gi|239582767 slingshot homolog 3 [Homo sapiens] 83 5e-16
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 81 1e-15
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 81 1e-15
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 81 1e-15
gi|56237018 testis and skeletal muscle-specific dual specificity... 80 2e-15
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 794 bits (2050), Expect = 0.0
Identities = 394/394 (100%), Positives = 394/394 (100%)
Query: 1 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY 60
MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
Sbjct: 1 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY 60
Query: 61 ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE 120
ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
Sbjct: 61 ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE 120
Query: 121 DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD 180
DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
Sbjct: 121 DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD 180
Query: 181 LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY 240
LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
Sbjct: 181 LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY 240
Query: 241 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR 300
QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
Sbjct: 241 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR 300
Query: 301 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP 360
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
Sbjct: 301 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP 360
Query: 361 TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC 394
TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
Sbjct: 361 TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC 394
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 514 bits (1325), Expect = e-146
Identities = 250/251 (99%), Positives = 251/251 (100%)
Query: 144 KGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFL 203
+GGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFL
Sbjct: 53 QGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFL 112
Query: 204 YLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAI 263
YLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAI
Sbjct: 113 YLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAI 172
Query: 264 EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF 323
EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF
Sbjct: 173 EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF 232
Query: 324 MGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPY 383
MGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPY
Sbjct: 233 MGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPY 292
Query: 384 LHSPITTSPSC 394
LHSPITTSPSC
Sbjct: 293 LHSPITTSPSC 303
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 456 bits (1172), Expect = e-128
Identities = 233/369 (63%), Positives = 275/369 (74%), Gaps = 7/369 (1%)
Query: 26 GGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQ 85
G G LG +CLLLDCR F A +AG+I GSVNVR +TIVRRRAKG++ LE
Sbjct: 6 GTLDAGGLRALLG-ERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEH 64
Query: 86 ILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKG 145
I+P E+R RL +G Y AV++ DERS + + D T++L AL R A + LKG
Sbjct: 65 IVP-NAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKG 123
Query: 146 GYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYL 205
GYE FS+ PE CSK + P+ S + + GCSSC TPL+DQGGPVEILPFLYL
Sbjct: 124 GYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYL 183
Query: 206 GSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEY 265
GSAYHA+R+DMLDALGITAL+NVS++CPNHFEGHYQYK IPVEDNHKADISSWF EAI++
Sbjct: 184 GSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDF 243
Query: 266 IDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMG 325
ID++K+ GRV VHCQAGISRSATICLAYLM RV+L+EAFEFVKQRRSIISPNFSFMG
Sbjct: 244 IDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMG 303
Query: 326 QLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLH 385
QLLQFESQVLA C+AEA SP+ + +RG + T VF+FPVS+ VHS S+L YL
Sbjct: 304 QLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTT-----VFNFPVSIPVHSTNSALSYLQ 358
Query: 386 SPITTSPSC 394
SPITTSPSC
Sbjct: 359 SPITTSPSC 367
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 286 bits (731), Expect = 3e-77
Identities = 175/376 (46%), Positives = 226/376 (60%), Gaps = 32/376 (8%)
Query: 41 SGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKG-SVSLEQILPAEEEVRARLRS 99
+ +C++LDCRP+LA +A + GS+NV N++V RRA+G +VS +LP +E RARL
Sbjct: 19 AAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLP-DEAARARLLQ 77
Query: 100 ---GLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTD-ICLLKGGYERFSSEYP 155
G +AV+V D+ S + LRE+S +V+ +L + LKGGYE F SEYP
Sbjct: 78 EGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYP 137
Query: 156 EFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPL--------HDQGGPVEILPFLYLGS 207
E C K P+ E S CG P+ +DQGGPVEILPFLYLGS
Sbjct: 138 ECCVDVK-------PISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGS 190
Query: 208 AYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYID 267
AYHA++ + L L ITALLNVS H YK IPVED+H ADISS F EAI++ID
Sbjct: 191 AYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFID 250
Query: 268 AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL 327
V++ G+VLVHC+AGISRS TIC+AYLM K+ RL+EAF+++KQRRS++SPNF FMGQL
Sbjct: 251 CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQL 310
Query: 328 LQFESQVLAT-------SCAAEAASPS--GPLRERGKTPATPTSQFVFSFPVSVGVHSAP 378
LQ+ES++L + SC EAA S G L+ F S V HS
Sbjct: 311 LQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTV 370
Query: 379 SSLPYLHSPITTSPSC 394
S L SP+ T+ SC
Sbjct: 371 SELS--RSPVATATSC 384
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 281 bits (720), Expect = 6e-76
Identities = 162/336 (48%), Positives = 211/336 (62%), Gaps = 30/336 (8%)
Query: 4 MEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILG 63
+E RE++C+ L L+ RD + LLLDCRPFLA ++
Sbjct: 3 LEAARELECAALGTLL-RDPR----------------EAERTLLLDCRPFLAFCRRHVRA 45
Query: 64 SVNVRCNTIVRRRAKG--SVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRED 121
+ V N ++RRRA+G + L +LP + +R RL G + +V DE S LR D
Sbjct: 46 ARPVPWNALLRRRARGPPAAVLACLLP-DRALRTRLVRGELARAVVLDEGSASVAELRPD 104
Query: 122 STVSLVVQAL--RRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPL 179
S +++ AL A T + L+GG++ F P+ CS+ A P +PP+ +
Sbjct: 105 SPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPA-----PALPPTGDKT- 158
Query: 180 DLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGH 239
S P++DQGGPVEILP+L+LGS H++ L A GITA+LNVS+ CPNHFEG
Sbjct: 159 --SRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGL 216
Query: 240 YQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKK 299
++YK IPVEDN +IS+WF EAI +ID VK+ GRVLVHCQAGISRSATICLAYLM +
Sbjct: 217 FRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSR 276
Query: 300 RVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVL 335
RVRL+EAF+FVKQRR +ISPNFSFMGQLLQFE+QVL
Sbjct: 277 RVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVL 312
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 182 bits (462), Expect = 5e-46
Identities = 125/365 (34%), Positives = 187/365 (51%), Gaps = 47/365 (12%)
Query: 24 NGGGAGGSGSHGTLGLP--------------SGGKCLLLDCRPFLAHSAGYILGSVNVRC 69
+G G G + G +P G LLLDCRP + +I ++N+
Sbjct: 37 SGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAI 96
Query: 70 -NTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSP--RAESLREDSTVSL 126
++RR KG++ + I+P + + V++YDE + + E S + L
Sbjct: 97 PGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGL 156
Query: 127 VVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLG---- 182
++Q LR + L+GG+ +F +EY E C ++ P PP T L LG
Sbjct: 157 LLQKLRDDG--CQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPP--TSVLGLGGLRI 212
Query: 183 ---CS--------------SCGTPLHDQ--GGPVEILPFLYLGSAYHAARRDMLDALGIT 223
CS S G+P+ PV+ILP+LYLG A + D+L GI
Sbjct: 213 SSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIK 272
Query: 224 ALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 281
+LNV+ + PN FE G + YK IP+ D+ ++S +F EAI +ID + + VLVHC
Sbjct: 273 YILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCL 332
Query: 282 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV-LATSCA 340
AGISRS T+ +AYLM K + L +A++FVK+++S ISPNF+FMGQLL FE + L++ C
Sbjct: 333 AGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCD 392
Query: 341 AEAAS 345
A+S
Sbjct: 393 NHASS 397
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 176 bits (447), Expect = 3e-44
Identities = 130/372 (34%), Positives = 186/372 (50%), Gaps = 54/372 (14%)
Query: 40 PSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLR 98
P + LLLDCR + + I G+++V ++ RR + GS+S+ +LP L+
Sbjct: 17 PPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPP-----LQ 71
Query: 99 SGLYSAVIVYDERSPR---------AESLREDSTVSLVVQALRRNAERTDICLLKGGYER 149
+ V++YD+ R AE +S + ++Q LR L+GG+ R
Sbjct: 72 PPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA--YYLQGGFSR 129
Query: 150 FSSEYPEFCSKTKA------LAAIPPPVPPSATEPLDLG--CS-----------SCGTPL 190
F +E P C + A +A +P PVP L LG CS SCG L
Sbjct: 130 FQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCG--L 187
Query: 191 HDQGG-----------PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE-- 237
+G PV+ILP LYLGSA +A + L LGI +LNV+ + PN FE
Sbjct: 188 DSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKN 247
Query: 238 GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMM 297
G + YK IP+ D+ ++S +F EAIE+ID VLVHC AG+SRS T+ +AYLM
Sbjct: 248 GDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQ 307
Query: 298 KKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTP 357
K + L +A++ VK+++S ISPNF+FMGQLL FE + ++ G P
Sbjct: 308 KLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPP 367
Query: 358 A---TPTSQFVF 366
+ TPTS F
Sbjct: 368 SFFTTPTSDGAF 379
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 169 bits (428), Expect = 4e-42
Identities = 118/349 (33%), Positives = 183/349 (52%), Gaps = 34/349 (9%)
Query: 44 KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRA-KGSVSLEQILPAEEEVRARLRSGLY 102
+ LL+DCRP + + +I ++NV I+ RR KG++ + + E+ R
Sbjct: 33 RLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGT 92
Query: 103 SAVIVYDERSPR-AESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKT 161
V++YDE S E+ +S + L+++ L+ R L+GG+ +F +E+ C
Sbjct: 93 DTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRA--FYLEGGFSKFQAEFSLHCETN 150
Query: 162 K--ALAAIPPPVPPSATEPLDLGCSSC------------------GTPLHDQ--GGPVEI 199
+ ++ PP+P L + S G+PL + PVEI
Sbjct: 151 LDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEI 210
Query: 200 LPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISS 257
LPFLYLG A + D+L+ GI +LNV+ + PN FE G ++YK IP+ D+ ++S
Sbjct: 211 LPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQ 270
Query: 258 WFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSII 317
+F EAI +ID + VLVHC AGISRS T+ +AYLM K + + +A++ VK ++S I
Sbjct: 271 FFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNI 330
Query: 318 SPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVF 366
SPNF+FMGQLL FE + L S + P+ L TP++Q V+
Sbjct: 331 SPNFNFMGQLLDFE-RTLGLSSPCDNRVPAQQLYF-----TTPSNQNVY 373
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 168 bits (425), Expect = 9e-42
Identities = 108/323 (33%), Positives = 175/323 (54%), Gaps = 28/323 (8%)
Query: 43 GKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLRSGL 101
G L++D R F+ +++ ++L SVN+ C+ +V+RR + G V++ +++ + R+++ +
Sbjct: 25 GGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELI--QPAARSQVEATE 82
Query: 102 YSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKT 161
V+VYD+ + A L DS +S+++ L + + +L GG+ FSS +P C
Sbjct: 83 PQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFD--SVAILTGGFATFSSCFPGLCEGK 140
Query: 162 KALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALG 221
P+A P+ L P G ILP LYLGS +D++ G
Sbjct: 141 -----------PAALLPMSLSQPCLPVP---SVGLTRILPHLYLGSQKDVLNKDLMTQNG 186
Query: 222 ITALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHC 280
I+ +LN S+ CP F ++ +P+ DN+ + W ++IE+ID K +V+VHC
Sbjct: 187 ISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHC 246
Query: 281 QAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFE-SQVLATSC 339
AGISRSATI +AY+M + ++A+ FVK RR ISPNF+F+GQLL++E S L +
Sbjct: 247 LAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAAL 306
Query: 340 AAEAASPSGPLRERGKTPATPTS 362
+ +PSG TP P S
Sbjct: 307 QGDPGTPSG-------TPEPPPS 322
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 167 bits (422), Expect = 2e-41
Identities = 101/314 (32%), Positives = 167/314 (53%), Gaps = 36/314 (11%)
Query: 39 LPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRA--KGSVSLEQILPAEEEVRAR 96
LPS G +++DCRPF+ ++ +I G+V++ C + RR +G +++ ++ E +
Sbjct: 167 LPSQGP-VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREG-KDS 224
Query: 97 LRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPE 156
+ +IVYDE + + + +V+++L+R E + +LKGG F +
Sbjct: 225 FKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKR--EGKEPLVLKGGLSSFKQNHEN 282
Query: 157 FCSKTKAL--------------AAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPF 202
C + L + +P P+P TP + ILPF
Sbjct: 283 LCDNSLQLQECREVGGGASAASSLLPQPIPT--------------TPDIENAELTPILPF 328
Query: 203 LYLGSAYHAARRDMLDALGITALLNVSSDCP-NHFE-GHYQYKCIPVEDNHKADISSWFM 260
L+LG+ A D + L I ++NV++ P H+E G + YK +P D++K ++ +F
Sbjct: 329 LFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFE 388
Query: 261 EAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPN 320
EA E+I+ C +L+HCQAG+SRSATI +AYLM R+ + +A++FVK +R IISPN
Sbjct: 389 EAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPN 448
Query: 321 FSFMGQLLQFESQV 334
+FMGQLL+FE +
Sbjct: 449 LNFMGQLLEFEEDL 462
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 163 bits (413), Expect = 2e-40
Identities = 113/365 (30%), Positives = 187/365 (51%), Gaps = 43/365 (11%)
Query: 44 KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLRSGLY 102
K LL+D RPF+ ++ +IL ++N+ C+ +++RR + V + +++ + + ++
Sbjct: 25 KVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELI--QHSAKHKVDIDCS 82
Query: 103 SAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTK 162
V+VYD+ S SL D +++++ L ++ + LL GG+ FS +P C
Sbjct: 83 QKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFN--SVHLLAGGFAEFSRCFPGLCEGKS 140
Query: 163 ALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGI 222
L VP ++P P+ + G P ILP LYLG ++++ GI
Sbjct: 141 TL------VPTCISQPC--------LPVANIG-PTRILPNLYLGCQRDVLNKELMQQNGI 185
Query: 223 TALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 281
+LN S+ CP F + +PV D+ I W +++++I+ K G VLVHC
Sbjct: 186 GYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCL 245
Query: 282 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAA 341
AGISRSATI +AY+M + + L+EA+ FVK++R ISPNF+F+GQLL +E ++ + A+
Sbjct: 246 AGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGAS 305
Query: 342 EAAS---------PSGPL------RERGKTPATP------TSQFVFSFPV-SVGVHSAPS 379
S P+ P+ ++ +TP +P TS+ PV V S PS
Sbjct: 306 GPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPS 365
Query: 380 SLPYL 384
P L
Sbjct: 366 VQPSL 370
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 111 bits (278), Expect = 1e-24
Identities = 61/157 (38%), Positives = 86/157 (54%)
Query: 192 DQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNH 251
D GG +I L+LG A+ R +L A GIT ++N + + PN ++Y +P+ D
Sbjct: 23 DIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMP 82
Query: 252 KADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 311
A I +F + I +V G LVHC AG+SRSAT+C+AYLM V L EA+ +VK
Sbjct: 83 HAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVK 142
Query: 312 QRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
RR +I PN F QL+ +E Q+ S +P G
Sbjct: 143 ARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYG 179
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 110 bits (274), Expect = 3e-24
Identities = 54/120 (45%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Query: 217 LDALGITALLNVSSDCP-NHFE-GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRG 274
+ L I ++NV++ P H+E G + YK +P D++K ++ +F EA E+I+ C
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 275 RVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 334
+L+HCQAG+SRSATI +AYLM R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 110 bits (274), Expect = 3e-24
Identities = 54/120 (45%), Positives = 82/120 (68%), Gaps = 2/120 (1%)
Query: 217 LDALGITALLNVSSDCP-NHFE-GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRG 274
+ L I ++NV++ P H+E G + YK +P D++K ++ +F EA E+I+ C
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 275 RVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 334
+L+HCQAG+SRSATI +AYLM R+ + +A++FVK +R IISPN +FMGQLL+FE +
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 102 bits (253), Expect = 8e-22
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 15/186 (8%)
Query: 196 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 255
P I LYLGS ++A+ + L G+ +LNV+ + N F G + Y I V D D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368
Query: 256 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 315
+ + EA +I+ K + LVHC+ G+SRSA+ +AY M + LE+A+ +VKQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428
Query: 316 IISPNFSFMGQLLQFES--------------QVLATSCAAEAASPSGPLRERGKTP-ATP 360
I PN FM QL ++E Q +S P+GP +TP TP
Sbjct: 429 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 488
Query: 361 TSQFVF 366
SQ F
Sbjct: 489 ESQLPF 494
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 102 bits (253), Expect = 8e-22
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 15/186 (8%)
Query: 196 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 255
P I LYLGS ++A+ + L G+ +LNV+ + N F G + Y I V D D+
Sbjct: 320 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 379
Query: 256 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 315
+ + EA +I+ K + LVHC+ G+SRSA+ +AY M + LE+A+ +VKQ+RS
Sbjct: 380 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 439
Query: 316 IISPNFSFMGQLLQFES--------------QVLATSCAAEAASPSGPLRERGKTP-ATP 360
I PN FM QL ++E Q +S P+GP +TP TP
Sbjct: 440 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 499
Query: 361 TSQFVF 366
SQ F
Sbjct: 500 ESQLPF 505
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 102 bits (253), Expect = 8e-22
Identities = 65/186 (34%), Positives = 94/186 (50%), Gaps = 15/186 (8%)
Query: 196 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI 255
P I LYLGS ++A+ + L G+ +LNV+ + N F G + Y I V D D+
Sbjct: 309 PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDL 368
Query: 256 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS 315
+ + EA +I+ K + LVHC+ G+SRSA+ +AY M + LE+A+ +VKQ+RS
Sbjct: 369 LAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS 428
Query: 316 IISPNFSFMGQLLQFES--------------QVLATSCAAEAASPSGPLRERGKTP-ATP 360
I PN FM QL ++E Q +S P+GP +TP TP
Sbjct: 429 ITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTP 488
Query: 361 TSQFVF 366
SQ F
Sbjct: 489 ESQLPF 494
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 99.4 bits (246), Expect = 5e-21
Identities = 49/148 (33%), Positives = 87/148 (58%)
Query: 190 LHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVED 249
L P +I ++LGS ++A+ + L G+ +LNV+ + N F G ++Y I V D
Sbjct: 302 LGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYD 361
Query: 250 NHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309
D+ +++ + ++I K + LVHC+ G+SRSA+ +AY M + L+ A+++
Sbjct: 362 EEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
Query: 310 VKQRRSIISPNFSFMGQLLQFESQVLAT 337
VK+RR++ PN SFM QL +++ +LA+
Sbjct: 422 VKERRTVTKPNPSFMRQLEEYQGILLAS 449
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 95.1 bits (235), Expect = 1e-19
Identities = 57/168 (33%), Positives = 88/168 (52%), Gaps = 4/168 (2%)
Query: 185 SCGTPLHDQ----GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY 240
SC P+ + G +I LY+ + A + ML + IT ++NVS + N
Sbjct: 5 SCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI 64
Query: 241 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR 300
QY +PV D+ + + +F ++I +V+ +GR L+HC AG+SRSA +CLAYLM
Sbjct: 65 QYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHA 124
Query: 301 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
+ L +A + K R II PN F QL+ +E Q+ + +SP G
Sbjct: 125 MSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVG 172
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 90.5 bits (223), Expect = 2e-18
Identities = 53/141 (37%), Positives = 73/141 (51%)
Query: 199 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 258
I P+L LGS A D L +T +LNV+ N F + YK I + D + +I S+
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
Query: 259 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 318
F E E+I+ K G VLVHC AG+SR+A I + +LM ++ AF VK R I
Sbjct: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
Query: 319 PNFSFMGQLLQFESQVLATSC 339
PN FM QL ++ + C
Sbjct: 189 PNSGFMEQLRTYQEGKESNKC 209
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 88.2 bits (217), Expect = 1e-17
Identities = 52/151 (34%), Positives = 80/151 (52%)
Query: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISS 257
+I L+L + A + +L + ITA++N S + N F QY +PV D + +
Sbjct: 24 QITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYD 83
Query: 258 WFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSII 317
+F + I + +GR L+HC AG+SRSA++CLAYLM + L +A + K RR II
Sbjct: 84 FFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPII 143
Query: 318 SPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
PN F QL+ +E ++ + SP G
Sbjct: 144 RPNNGFWEQLINYEFKLFNNNTVRMINSPVG 174
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 84.7 bits (208), Expect = 1e-16
Identities = 63/176 (35%), Positives = 89/176 (50%), Gaps = 15/176 (8%)
Query: 166 AIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITAL 225
A P P E L G SSC E+ P L++G A A R L LGIT +
Sbjct: 15 ATPCPSILELEELLRAGKSSCSRV-------DEVWPNLFIGDAATANNRFELWKLGITHV 67
Query: 226 LNVSSD---C---PNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRG-RVLV 278
LN + C P+ + Y +P D DIS++F A ++I + G +VLV
Sbjct: 68 LNAAHKGLYCQGGPDFYGSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLV 127
Query: 279 HCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV 334
HC G+SRSAT+ LAYLM+ +R+ L +A V+Q R + PN F+ QL + + Q+
Sbjct: 128 HCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVF-PNRGFLHQLCRLDQQL 182
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 84.0 bits (206), Expect = 2e-16
Identities = 57/143 (39%), Positives = 78/143 (54%), Gaps = 7/143 (4%)
Query: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSD----CPNHFEG-HYQYKCIPVEDNHK 252
E+ P LYLG A R L LGIT +LN S P +EG +Y + D+
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
Query: 253 ADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVK 311
D+S F A ++I A+ G++LVHC G+SRSAT+ LAYLM+ + L EA + VK
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
Query: 312 QRRSIISPNFSFMGQLLQFESQV 334
R II PN F+ QLL + ++
Sbjct: 184 DHRGII-PNRGFLRQLLALDRRL 205
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 84.0 bits (206), Expect = 2e-16
Identities = 49/143 (34%), Positives = 71/143 (49%)
Query: 197 VEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADIS 256
V + P L+LGSA A + L G+T +NVS P +PV D+ D+
Sbjct: 20 VRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLL 79
Query: 257 SWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSI 316
+ ++A G LV+C+ G SRSA +C AYLM + + L +AF+ VK R +
Sbjct: 80 AHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPV 139
Query: 317 ISPNFSFMGQLLQFESQVLATSC 339
PN F QL ++E + A SC
Sbjct: 140 AEPNPGFWSQLQKYEEALQAQSC 162
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 83.6 bits (205), Expect = 3e-16
Identities = 51/147 (34%), Positives = 82/147 (55%), Gaps = 11/147 (7%)
Query: 198 EILPFLYLGSAYHAARRDMLDALGITALLN---------VSSDCPNHFEGHYQYKCIPVE 248
E+ P +Y+G+A A L LGIT +LN V+++ + + Y I
Sbjct: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
Query: 249 DNHKADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAF 307
D + ++S++F A ++ID A+ GRVLVHC+ G SRS T+ +AYLMM++++ ++ A
Sbjct: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
Query: 308 EFVKQRRSIISPNFSFMGQLLQFESQV 334
V+Q R I PN F+ QL Q ++
Sbjct: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 82.8 bits (203), Expect = 5e-16
Identities = 46/139 (33%), Positives = 74/139 (53%)
Query: 199 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 258
I P LYLGS ++AA + L +T +LN++ + N + + Y + + D A +
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
Query: 259 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 318
+ E +I+A + VLVHC+ G+SRSA LAY M + LE+A V++ R I
Sbjct: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
Query: 319 PNFSFMGQLLQFESQVLAT 337
PN F+ QL ++ + A+
Sbjct: 452 PNPGFLRQLQIYQGILTAS 470
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 1e-15
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)
Query: 198 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 248
EILP L+LG Y +A + L L GIT ++ + + PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 249 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 308
DN +I +F E+ID G+VLVH AGISRSA +AY+M ++ +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 309 FVKQRRSIISPNFSFMGQLLQFESQVLA 336
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 1e-15
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)
Query: 198 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 248
EILP L+LG Y +A + L L GIT ++ + + PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 249 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 308
DN +I +F E+ID G+VLVH AGISRSA +AY+M ++ +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 309 FVKQRRSIISPNFSFMGQLLQFESQVLA 336
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 81.3 bits (199), Expect = 1e-15
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)
Query: 198 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 248
EILP L+LG Y +A + L L GIT ++ + + PN F+ ++Y + +
Sbjct: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
Query: 249 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 308
DN +I +F E+ID G+VLVH AGISRSA +AY+M ++ +AF
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 309 FVKQRRSIISPNFSFMGQLLQFESQVLA 336
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 80.5 bits (197), Expect = 2e-15
Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 9/145 (6%)
Query: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDC------PNHFEG-HYQYKCIPVEDN 250
E+ P L+LG AY A + L LGIT ++N ++ + G +Y I +DN
Sbjct: 48 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 107
Query: 251 HKADISSWFMEAIEYIDAVKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309
D+S +F+ YI A +GRVLVHC G+SRSAT+ LA+LM+ + + L EA +
Sbjct: 108 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 167
Query: 310 VKQRRSIISPNFSFMGQLLQFESQV 334
V+ R+ I PN F+ QL ++++
Sbjct: 168 VQAHRN-ICPNSGFLRQLQVLDNRL 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,502,664
Number of Sequences: 37866
Number of extensions: 822023
Number of successful extensions: 4610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 4481
Number of HSP's gapped (non-prelim): 145
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.